{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:45:36Z","timestamp":1763747136363},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2012,7,31]],"date-time":"2012-07-31T00:00:00Z","timestamp":1343692800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Histochem Cell Biol"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1007\/s00418-012-0997-1","type":"journal-article","created":{"date-parts":[[2012,7,30]],"date-time":"2012-07-30T04:41:20Z","timestamp":1343623280000},"page":"925-932","source":"Crossref","is-referenced-by-count":20,"title":["Human placental transthyretin in fetal growth restriction in combination with preeclampsia and the HELLP syndrome"],"prefix":"10.1007","volume":"138","author":[{"given":"Arrigo","family":"Fruscalzo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Schmitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Klockenbusch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"K\u00f6hler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. P.","family":"Londero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Siwetz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Huppertz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,7,31]]},"reference":[{"key":"997_CR1","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1007\/s004150170109","volume":"248","author":"D Adams","year":"2001","unstructured":"Adams D (2001) Hereditary and acquired amyloid neuropathies. J Neurol 248:647\u2013657","journal-title":"J Neurol"},{"key":"997_CR2","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/sj.jp.7211398","volume":"25","author":"N Ambalavanan","year":"2005","unstructured":"Ambalavanan N, Ross AC, Carlo WA (2005) Retinol-binding protein, transthyretin, and C-reactive protein in extremely low birth weight (ELBW) infants. J Perinatol 25:714\u2013719","journal-title":"J Perinatol"},{"key":"997_CR3","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1001\/archneur.62.7.1057","volume":"62","author":"Y Ando","year":"2005","unstructured":"Ando Y, Nakamura M, Araki S (2005) Transthyretin-related familial amyloidotic polyneuropathy. Arch Neurol 62:1057\u20131062","journal-title":"Arch Neurol"},{"key":"997_CR4","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1194\/jlr.M800296-JLR200","volume":"50","author":"KR Atkinson","year":"2009","unstructured":"Atkinson KR, Blumenstein M, Black MA, Wu SH, Kasabov N, Taylor RS, Cooper GJ, North RA (2009) An altered pattern of circulating apolipoprotein E3 isoforms is implicated in preeclampsia. J Lipid Res 50:71\u201380","journal-title":"J Lipid Res"},{"key":"997_CR5","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1097\/01.ogx.0000146948.19308.c5","volume":"59","author":"JK Baxter","year":"2004","unstructured":"Baxter JK, Weinstein L (2004) HELLP syndrome: the state of the art. Obstet Gynecol Surv 59:838\u2013845","journal-title":"Obstet Gynecol Surv"},{"key":"997_CR6","doi-asserted-by":"crossref","first-page":"IX","DOI":"10.3109\/10641950109152635","volume":"20","author":"MA Brown","year":"2001","unstructured":"Brown MA, Lindheimer MD, de Swiet M, Van Assche A, Moutquin JM (2001) The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy 20:IX\u2013XIV","journal-title":"Hypertens Pregnancy"},{"issue":"551","key":"997_CR7","first-page":"e516","volume":"199","author":"IA Buhimschi","year":"2008","unstructured":"Buhimschi IA, Zhao G, Funai EF, Harris N, Sasson IE, Bernstein IM, Saade GR, Buhimschi CS (2008) Proteomic profiling of urine identifies specific fragments of SERPINA1 and albumin as biomarkers of preeclampsia. Am J Obstet Gynecol 199(551):e516\u2013e551","journal-title":"Am J Obstet Gynecol"},{"key":"997_CR8","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1007\/s00018-009-0109-0","volume":"66","author":"JN Buxbaum","year":"2009","unstructured":"Buxbaum JN, Reixach N (2009) Transthyretin: the servant of many masters. Cell Mol Life Sci 66:3095\u20133101","journal-title":"Cell Mol Life Sci"},{"key":"997_CR9","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.mehy.2010.08.017","volume":"76","author":"Y Chen","year":"2011","unstructured":"Chen Y, Zhang Z (2011) Does transthyretin function as one of contributors for preeclampsia? Med Hypotheses 76:8\u201310","journal-title":"Med Hypotheses"},{"key":"997_CR10","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.placenta.2009.11.004","volume":"31","author":"B Gharesi-Fard","year":"2010","unstructured":"Gharesi-Fard B, Zolghadri J, Kamali-Sarvestani E (2010) Proteome differences of placenta between pre-eclampsia and normal pregnancy. Placenta 31:121\u2013125","journal-title":"Placenta"},{"key":"997_CR11","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jchromb.2006.06.002","volume":"840","author":"JC Heitner","year":"2006","unstructured":"Heitner JC, Koy C, Kreutzer M, Gerber B, Reimer T, Glocker MO (2006) Differentiation of HELLP patients from healthy pregnant women by proteome analysis\u2013on the way towards a clinical marker set. J Chromatogr B Anal Technol Biomed Life Sci 840:10\u201319","journal-title":"J Chromatogr B Anal Technol Biomed Life Sci"},{"key":"997_CR12","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1161\/HYPERTENSIONAHA.107.107607","volume":"51","author":"B Huppertz","year":"2008","unstructured":"Huppertz B (2008) Placental origins of preeclampsia: challenging the current hypothesis. Hypertension 51:970\u2013975","journal-title":"Hypertension"},{"key":"997_CR13","first-page":"417","volume":"300","author":"NS Jeyashekar","year":"2005","unstructured":"Jeyashekar NS, Sadana A, Vo-Dinh T (2005) Protein amyloidose misfolding: mechanisms, detection, and pathological implications. Methods Mol Biol 300:417\u2013435","journal-title":"Methods Mol Biol"},{"key":"997_CR14","doi-asserted-by":"crossref","first-page":"2610","DOI":"10.1210\/jc.2009-0048","volume":"94","author":"KA Landers","year":"2009","unstructured":"Landers KA, McKinnon BD, Li H, Subramaniam VN, Mortimer RH, Richard K (2009) Carrier-mediated thyroid hormone transport into placenta by placental transthyretin. J Clin Endocrinol Metab 94:2610\u20132616","journal-title":"J Clin Endocrinol Metab"},{"key":"997_CR15","doi-asserted-by":"crossref","first-page":"6714","DOI":"10.1210\/jc.2005-0696","volume":"90","author":"B McKinnon","year":"2005","unstructured":"McKinnon B, Li H, Richard K, Mortimer R (2005) Synthesis of thyroid hormone binding proteins transthyretin and albumin by human trophoblast. J Clin Endocrinol Metab 90:6714\u20136720","journal-title":"J Clin Endocrinol Metab"},{"key":"997_CR16","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1056\/NEJMra023144","volume":"349","author":"G Merlini","year":"2003","unstructured":"Merlini G, Bellotti V (2003) Molecular mechanisms of amyloidosis. N Engl J Med 349:583\u2013596","journal-title":"N Engl J Med"},{"key":"997_CR17","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1002\/1520-6661(200009\/10)9:5<282::AID-MFM5>3.0.CO;2-J","volume":"9","author":"SC Mitra","year":"2000","unstructured":"Mitra SC, Seshan SV, Riachi LE (2000) Placental vessel morphometry in growth retardation and increased resistance of the umbilical artery Doppler flow. J Matern Fetal Med 9:282\u2013286","journal-title":"J Matern Fetal Med"},{"key":"997_CR18","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0167-4838(00)00140-0","volume":"1482","author":"HL Monaco","year":"2000","unstructured":"Monaco HL (2000) The transthyretin-retinol-binding protein complex. Biochim Biophys Acta 1482:65\u201372","journal-title":"Biochim Biophys Acta"},{"key":"997_CR19","volume-title":"Diagnostic imaging of fetal anomalies","year":"2003","unstructured":"Nyberg DA, McGahan JP, Pretorius DH, Pilu G (eds) (2003) Diagnostic imaging of fetal anomalies. Lippinkott Williams & Wilkins, Baltimore"},{"key":"997_CR20","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1447-0756.2000.tb01343.x","volume":"26","author":"P Panburana","year":"2000","unstructured":"Panburana P, Phuapradit W, Puchaiwatananon O (2000) Antioxidant nutrients and lipid peroxide levels in Thai preeclamptic pregnant women. J Obstet Gynaecol Res 26:377\u2013381","journal-title":"J Obstet Gynaecol Res"},{"key":"997_CR21","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.placenta.2011.09.007","volume":"32","author":"J Patel","year":"2011","unstructured":"Patel J, Landers KA, Li H, Mortimer RH, Richard K (2011) Ontogenic changes in placental transthyretin. Placenta 32:817\u2013822","journal-title":"Placenta"},{"key":"997_CR22","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1530\/JOE-11-0348","volume":"212","author":"J Patel","year":"2012","unstructured":"Patel J, Landers KA, Mortimer RH, Richard K (2012) Expression and uptake of the thyroxine-binding protein transthyretin is regulated by oxygen in primary trophoblast placental cells. J Endocrinol 212:159\u2013167","journal-title":"J Endocrinol"},{"key":"997_CR23","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1016\/j.jasms.2009.12.013","volume":"21","author":"U Pecks","year":"2010","unstructured":"Pecks U, Seidenspinner F, Rower C, Reimer T, Rath W, Glocker MO (2010) Multifactorial analysis of affinity-mass spectrometry data from serum protein samples: a strategy to distinguish patients with preeclampsia from matching control individuals. J Am Soc Mass Spectrom 21:1699\u20131711","journal-title":"J Am Soc Mass Spectrom"},{"key":"997_CR24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbapap.2004.09.023","volume":"1703","author":"P Raghu","year":"2004","unstructured":"Raghu P, Sivakumar B (2004) Interactions amongst plasma retinol-binding protein, transthyretin and their ligands: implications in vitamin A homeostasis and transthyretin amyloidosis. Biochim Biophys Acta 1703:1\u20139","journal-title":"Biochim Biophys Acta"},{"key":"997_CR25","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1126\/science.1111726","volume":"308","author":"CW Redman","year":"2005","unstructured":"Redman CW, Sargent IL (2005) Latest advances in understanding preeclampsia. Science 308:1592\u20131594","journal-title":"Science"},{"key":"997_CR26","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1073\/pnas.0400062101","volume":"101","author":"N Reixach","year":"2004","unstructured":"Reixach N, Deechongkit S, Jiang X, Kelly JW, Buxbaum JN (2004) Tissue damage in the amyloidoses: transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture. Proc Natl Acad Sci USA 101:2817\u20132822","journal-title":"Proc Natl Acad Sci USA"},{"key":"997_CR27","doi-asserted-by":"crossref","first-page":"5342","DOI":"10.1111\/j.1742-4658.2009.07244.x","volume":"276","author":"SJ Richardson","year":"2009","unstructured":"Richardson SJ (2009) Evolutionary changes to transthyretin: evolution of transthyretin biosynthesis. FEBS J 276:5342\u20135356","journal-title":"FEBS J"},{"key":"997_CR28","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.bpobgyn.2009.05.003","volume":"23","author":"S Sankaran","year":"2009","unstructured":"Sankaran S, Kyle PM (2009) Aetiology and pathogenesis of IUGR. Best Pract Res Clin Obstet Gynaecol 23:765\u2013777","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"Suppl 1","key":"997_CR29","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/13506129.2003.12088562","volume":"10","author":"MJ Saraiva","year":"2003","unstructured":"Saraiva MJ (2003) Cellular consequences of transthyretin deposition. Amyloid 10(Suppl 1):13\u201316","journal-title":"Amyloid"},{"key":"997_CR30","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.cca.2009.06.031","volume":"407","author":"X Shangguan","year":"2009","unstructured":"Shangguan X, Liu F, Wang H, He J, Dong M (2009) Alterations in serum adipocyte fatty acid binding protein and retinol binding protein-4 in normal pregnancy and preeclampsia. Clin Chim Acta 407:58\u201361","journal-title":"Clin Chim Acta"},{"key":"997_CR31","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0140-6736(05)71003-5","volume":"365","author":"B Sibai","year":"2005","unstructured":"Sibai B, Dekker G, Kupferminc M (2005) Pre-eclampsia. Lancet 365:785\u2013799","journal-title":"Lancet"},{"key":"997_CR32","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/j.bbrc.2008.10.121","volume":"377","author":"K Sorgjerd","year":"2008","unstructured":"Sorgjerd K, Klingstedt T, Lindgren M, Kagedal K, Hammarstrom P (2008) Prefibrillar transthyretin oligomers and cold stored native tetrameric transthyretin are cytotoxic in cell culture. Biochem Biophys Res Commun 377:1072\u20131078","journal-title":"Biochem Biophys Res Commun"},{"key":"997_CR33","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1016\/S0002-9440(10)63050-7","volume":"159","author":"MM Sousa","year":"2001","unstructured":"Sousa MM, Cardoso I, Fernandes R, Guimaraes A, Saraiva MJ (2001) Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: evidence for toxicity of nonfibrillar aggregates. Am J Pathol 159:1993\u20132000","journal-title":"Am J Pathol"},{"key":"997_CR34","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1159\/000292616","volume":"36","author":"J Uotila","year":"1993","unstructured":"Uotila J, Tuimala R, Pyykko K, Ahotupa M (1993) Pregnancy-induced hypertension is associated with changes in maternal and umbilical blood antioxidants. Gynecol Obstet Invest 36:153\u2013157","journal-title":"Gynecol Obstet Invest"},{"key":"997_CR35","first-page":"129","volume":"38","author":"E Vaisbuch","year":"2010","unstructured":"Vaisbuch E, Romero R, Mazaki-Tovi S, Erez O, Kim SK, Chaiworapongsa T, Gotsch F, Than NG, Dong Z, Pacora P, Lamont R, Yeo L, Hassan SS, Kusanovic JP (2010) Retinol binding protein 4\u2014a novel association with early-onset preeclampsia. J Perinat Med 38:129\u2013139","journal-title":"J Perinat Med"},{"key":"997_CR36","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1021\/pr060315z","volume":"6","author":"C Vascotto","year":"2007","unstructured":"Vascotto C, Salzano AM, D\u2019Ambrosio C, Fruscalzo A, Marchesoni D, di Loreto C, Scaloni A, Tell G, Quadrifoglio F (2007) Oxidized transthyretin in amniotic fluid as an early marker of preeclampsia. J Proteome Res 6:160\u2013170","journal-title":"J Proteome Res"},{"issue":"Suppl 1","key":"997_CR37","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1080\/13506129.2003.12088568","volume":"10","author":"P Westermark","year":"2003","unstructured":"Westermark P, Bergstrom J, Solomon A, Murphy C, Sletten K (2003) Transthyretin-derived senile systemic amyloidosis: clinicopathologic and structural considerations. Amyloid 10(Suppl 1):48\u201354","journal-title":"Amyloid"}],"container-title":["Histochemistry and Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-012-0997-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00418-012-0997-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-012-0997-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,12]],"date-time":"2020-07-12T02:57:41Z","timestamp":1594522661000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00418-012-0997-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,31]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["997"],"URL":"https:\/\/doi.org\/10.1007\/s00418-012-0997-1","relation":{},"ISSN":["0948-6143","1432-119X"],"issn-type":[{"value":"0948-6143","type":"print"},{"value":"1432-119X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,31]]}}}