{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T17:10:10Z","timestamp":1750180210445,"version":"3.41.0"},"reference-count":85,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T00:00:00Z","timestamp":1490227200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Histochem Cell Biol"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1007\/s00418-017-1555-7","type":"journal-article","created":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T13:51:19Z","timestamp":1490277079000},"page":"189-206","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Homer1 (VesL-1) in the rat esophagus: focus on myenteric plexus and neuromuscular junction"],"prefix":"10.1007","volume":"148","author":[{"given":"J.","family":"Zimmermann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. L.","family":"Neuhuber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Raab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,3,23]]},"reference":[{"issue":"2","key":"1555_CR1","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.jneumeth.2011.11.014","volume":"204","author":"R Ayala","year":"2012","unstructured":"Ayala R, Kett LR, Leach TL, Young AB, Dunah AW, Orlando LR (2012) Metabotropic glutamate receptor 1 (mGluR1): antibody specificity and receptor expression in cultured primary neurons. J Neurosci Methods 204(2):221\u2013226. doi: 10.1016\/j.jneumeth.2011.11.014","journal-title":"J Neurosci Methods"},{"issue":"2","key":"1555_CR2","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s004290050037","volume":"195","author":"HR Berthoud","year":"1997","unstructured":"Berthoud HR, Patterson LM, Neumann F, Neuhuber WL (1997) Distribution and structure of vagal afferent intraganglionic laminar endings (IGLEs) in the rat gastrointestinal tract. Anat Embryol (Berl) 195(2):183\u2013191","journal-title":"Anat Embryol (Berl)"},{"issue":"Pt 2","key":"1555_CR3","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1113\/jphysiol.2004.074799","volume":"562","author":"GS Bewick","year":"2005","unstructured":"Bewick GS, Reid B, Richardson C, Banks RW (2005) Autogenic modulation of mechanoreceptor excitability by glutamate release from synaptic-like vesicles: evidence from the rat muscle spindle primary sensory ending. J Physiol 562(Pt 2):381\u2013394. doi: 10.1113\/jphysiol.2004.074799","journal-title":"J Physiol"},{"issue":"4","key":"1555_CR4","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1038\/86075","volume":"4","author":"G Bhave","year":"2001","unstructured":"Bhave G, Karim F, Carlton SM, Gereau RWt (2001) Peripheral group I metabotropic glutamate receptors modulate nociception in mice. Nat Neurosci 4(4):417\u2013423. doi: 10.1038\/86075","journal-title":"Nat Neurosci"},{"issue":"2","key":"1555_CR5","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s00441-006-0274-5","volume":"326","author":"TM B\u00f6ckers","year":"2006","unstructured":"B\u00f6ckers TM (2006) The postsynaptic density. Cell Tissue Res 326(2):409\u2013422","journal-title":"Cell Tissue Res"},{"issue":"1","key":"1555_CR6","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1006\/bbrc.1999.1489","volume":"264","author":"TM B\u00f6ckers","year":"1999","unstructured":"B\u00f6ckers TM, Winter C, Smalla KH, Kreutz MR, Bockmann J, Seidenbecher C, Garner CC, Gundelfinger ED (1999) Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP\/GKAP family. Biochem Biophys Res Commun 264(1):247\u2013252","journal-title":"Biochem Biophys Res Commun"},{"issue":"4","key":"1555_CR7","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1046\/j.1471-4159.2002.01204.x","volume":"83","author":"J Bockmann","year":"2002","unstructured":"Bockmann J, Kreutz MR, Gundelfinger ED, B\u00f6ckers TM (2002) ProSAP\/Shank postsynaptic density proteins interact with insulin receptor tyrosine kinase substrate IRSp53. J Neurochem 83(4):1013\u20131017","journal-title":"J Neurochem"},{"issue":"6622","key":"1555_CR8","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1038\/386284a0","volume":"386","author":"PR Brakeman","year":"1997","unstructured":"Brakeman PR, Lanahan AA, O\u2019Brien R, Roche K, Barnes CA, Huganir RL, Worley PF (1997) Homer: a protein that selectively binds metabotropic glutamate receptors. Nature 386(6622):284\u2013288. doi: 10.1038\/386284a0","journal-title":"Nature"},{"issue":"4","key":"1555_CR9","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/cne.20194","volume":"475","author":"JH Brandst\u00e4tter","year":"2004","unstructured":"Brandst\u00e4tter JH, Dick O, B\u00f6ckers TM (2004) The postsynaptic scaffold proteins ProSAP1\/Shank2 and Homer1 are associated with glutamate receptor complexes at rat retinal synapses. J Comp Neurol 475(4):551\u2013563","journal-title":"J Comp Neurol"},{"issue":"2","key":"1555_CR10","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/(SICI)1096-9861(19980824)398:2<289::AID-CNE9>3.0.CO;2-X","volume":"398","author":"M D\u00fctsch","year":"1998","unstructured":"D\u00fctsch M, Eichhorn U, W\u00f6rl J, Wank M, Berthoud HR, Neuhuber WL (1998) Vagal and spinal afferent innervation of the rat esophagus: a combined retrograde tracing and immunocytochemical study with special emphasis on calcium-binding proteins. J Comp Neurol 398(2):289\u2013307","journal-title":"J Comp Neurol"},{"issue":"3","key":"1555_CR11","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1385\/MN:29:3:213","volume":"29","author":"M Ehrengruber","year":"2004","unstructured":"Ehrengruber M, Kato A, Inokuchi K, Hennou S (2004) Homer\/vesl proteins and their roles in CNS neurons. Mol Neurobiol 29(3):213\u2013227. doi: 10.1385\/MN:29:3:213","journal-title":"Mol Neurobiol"},{"issue":"4","key":"1555_CR12","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s00418-005-0083-z","volume":"125","author":"P Ewald","year":"2006","unstructured":"Ewald P, Neuhuber WL, Raab M (2006) Vesicular glutamate transporter 1 immunoreactivity in extrinsic and intrinsic innervation of the rat esophagus. Histochem Cell Biol 125(4):377\u2013395","journal-title":"Histochem Cell Biol"},{"issue":"47","key":"1555_CR13","doi-asserted-by":"publisher","first-page":"44722","DOI":"10.1074\/jbc.M207675200","volume":"277","author":"W Feng","year":"2002","unstructured":"Feng W, Tu J, Yang T, Vernon PS, Allen PD, Worley PF, Pessah IN (2002) Homer regulates gain of ryanodine receptor type 1 channel complex. J Biol Chem 277(47):44722\u201344730. doi: 10.1074\/jbc.M207675200","journal-title":"J Biol Chem"},{"issue":"1","key":"1555_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1471-4159.2008.05726.x","volume":"108","author":"L Foa","year":"2009","unstructured":"Foa L, Gasperini R (2009) Developmental roles for Homer: more than just a pretty scaffold. J Neurochem 108(1):1\u201310. doi: 10.1111\/j.1471-4159.2008.05726.x","journal-title":"J Neurochem"},{"issue":"1\u20132","key":"1555_CR15","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0014-2999(03)02147-2","volume":"476","author":"C Giaroni","year":"2003","unstructured":"Giaroni C, Zanetti E, Chiaravalli AM, Albarello L, Dominioni L, Capella C, Lecchini S, Frigo G (2003) Evidence for a glutamatergic modulation of the cholinergic function in the human enteric nervous system via NMDA receptors. Eur J Pharmacol 476(1\u20132):63\u201369","journal-title":"Eur J Pharmacol"},{"issue":"1","key":"1555_CR16","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.cell.2009.01.050","volume":"137","author":"MK Hayashi","year":"2009","unstructured":"Hayashi MK, Tang C, Verpelli C, Narayanan R, Stearns MH, Xu R-M, Li H, Sala C, Hayashi Y (2009) The postsynaptic density proteins Homer and Shank form a polymeric network structure. Cell 137(1):159\u2013171. doi: 10.1016\/j.cell.2009.01.050","journal-title":"Cell"},{"issue":"1","key":"1555_CR17","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.jneumeth.2011.11.009","volume":"204","author":"L Horling","year":"2012","unstructured":"Horling L, Neuhuber WL, Raab M (2012) Pitfalls using tyramide signal amplification (TSA) in the mouse gastrointestinal tract: endogenous streptavidin-binding sites lead to false positive staining. J Neurosci Methods 204(1):124\u2013132. doi: 10.1016\/j.jneumeth.2011.11.009","journal-title":"J Neurosci Methods"},{"issue":"19","key":"1555_CR18","doi-asserted-by":"publisher","first-page":"14283","DOI":"10.1074\/jbc.M611529200","volume":"282","author":"G Huang","year":"2007","unstructured":"Huang G, Kim JY, Dehoff M, Mizuno Y, Kamm KE, Worley PF, Muallem S, Zeng W (2007) Ca2+ signaling in microdomains: Homer1 Mediates The Interaction Between RyR2 and Cav1.2 to regulate excitation-contraction coupling. J Biol Chem 282(19):14283\u201314290. doi: 10.1074\/jbc.M611529200","journal-title":"J Biol Chem"},{"issue":"5862","key":"1555_CR19","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1126\/science.1151227","volume":"319","author":"GN Huang","year":"2008","unstructured":"Huang GN, Huso DL, Bouyain S, Tu J, McCorkell KA, May MJ, Zhu Y, Lutz M, Collins S, Dehoff M, Kang S, Whartenby K, Powell J, Leahy D, Worley PF (2008) NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins. Science 319(5862):476\u2013481. doi: 10.1126\/science.1151227","journal-title":"Science"},{"issue":"2","key":"1555_CR20","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/S0143-4160(03)00082-4","volume":"34","author":"S-Y Hwang","year":"2003","unstructured":"Hwang S-Y, Wei J, Westhoff JH, Duncan RS, Ozawa F, Volpe P, Inokuchi K, Koulen P (2003) Differential functional interaction of two Vesl\/Homer protein isoforms with ryanodine receptor type 1: a novel mechanism for control of intracellular calcium signaling. Cell Calcium 34(2):177\u2013184. doi: 10.1016\/S0143-4160(03)00082-4","journal-title":"Cell Calcium"},{"issue":"1\u20132","key":"1555_CR21","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.ejphar.2005.07.007","volume":"519","author":"J Jensen","year":"2005","unstructured":"Jensen J, Lehmann A, Uvebrant A, Carlsson A, Jerndal G, Nilsson K, Frisby C, Blackshaw LA, Mattsson JP (2005) Transient lower esophageal sphincter relaxations in dogs are inhibited by a metabotropic glutamate receptor 5 antagonist. Eur J Pharmacol 519(1\u20132):154\u2013157. doi: 10.1016\/j.ejphar.2005.07.007","journal-title":"Eur J Pharmacol"},{"issue":"19","key":"1555_CR22","doi-asserted-by":"crossref","first-page":"7238","DOI":"10.1523\/JNEUROSCI.20-19-07238.2000","volume":"20","author":"PJ Kammermeier","year":"2000","unstructured":"Kammermeier PJ, Xiao B, Tu JC, Worley PF, Ikeda SR (2000) Homer proteins regulate coupling of group I metabotropic glutamate receptors to N-type calcium and M-type potassium channels. J Neurosci 20(19):7238\u20137245","journal-title":"J Neurosci"},{"issue":"37","key":"1555_CR23","doi-asserted-by":"publisher","first-page":"23969","DOI":"10.1074\/jbc.273.37.23969","volume":"273","author":"A Kato","year":"1998","unstructured":"Kato A, Ozawa F, Saitoh Y, Fukazawa Y, Sugiyama H, Inokuchi K (1998) Novel members of the Vesl\/Homer family of PDZ proteins that bind metabotropic glutamate receptors. J Biol Chem 273(37):23969\u201323975. doi: 10.1074\/jbc.273.37.23969","journal-title":"J Biol Chem"},{"issue":"6","key":"1555_CR24","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/S0166-2236(96)01033-8","volume":"20","author":"MB Kennedy","year":"1997","unstructured":"Kennedy MB (1997) The postsynaptic density at glutamatergic synapses. Trends Neurosci 20(6):264\u2013268","journal-title":"Trends Neurosci"},{"issue":"5492","key":"1555_CR25","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1126\/science.290.5492.750","volume":"290","author":"MB Kennedy","year":"2000","unstructured":"Kennedy MB (2000) Signal-processing machines at the postsynaptic density. Science 290(5492):750\u2013754. doi: 10.1126\/science.290.5492.750","journal-title":"Science"},{"key":"1555_CR26","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s00418-008-0498-4","volume":"131","author":"C Kestler","year":"2009","unstructured":"Kestler C, Neuhuber W, Raab M (2009) Distribution of P2X3 receptor immunoreactivity in myenteric ganglia of the mouse esophagus. Histochem Cell Biol 131:13\u201327. doi: 10.1007\/s00418-008-0498-4 doi","journal-title":"Histochem Cell Biol"},{"issue":"6","key":"1555_CR27","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S1471-4892(01)00101-1","volume":"1","author":"AL Kirchgessner","year":"2001","unstructured":"Kirchgessner AL (2001) Glutamate in the enteric nervous system. Curr Opin Pharmacol 1(6):591\u2013596","journal-title":"Curr Opin Pharmacol"},{"issue":"22","key":"1555_CR28","doi-asserted-by":"crossref","first-page":"8804","DOI":"10.1523\/JNEUROSCI.17-22-08804.1997","volume":"17","author":"AL Kirchgessner","year":"1997","unstructured":"Kirchgessner AL, Liu MT, Alcantara F (1997) Excitotoxicity in the enteric nervous system. J Neurosci 17(22):8804\u20138816","journal-title":"J Neurosci"},{"key":"1555_CR29","volume-title":"Lokalisation und Verteilung von GluR2\/3-Rezeptorimmunit\u00e4t im \u00d6sophagus der Maus","author":"S K\u00f6nig","year":"2012","unstructured":"K\u00f6nig S (2012) Lokalisation und Verteilung von GluR2\/3-Rezeptorimmunit\u00e4t im \u00d6sophagus der Maus. Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen"},{"issue":"1\u20132","key":"1555_CR30","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.neulet.2004.02.039","volume":"360","author":"T Kraus","year":"2004","unstructured":"Kraus T, Neuhuber WL, Raab M (2004) Vesicular glutamate transporter 1 immunoreactivity in motor endplates of striated esophageal but not skeletal muscles in the mouse. Neurosci Lett 360(1\u20132):53\u201356","journal-title":"Neurosci Lett"},{"issue":"2","key":"1555_CR31","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s00441-007-0392-8","volume":"329","author":"T Kraus","year":"2007","unstructured":"Kraus T, Neuhuber WL, Raab M (2007) Distribution of vesicular glutamate transporter 1 (VGLUT1) in the mouse esophagus. Cell Tissue Res 329(2):205\u2013219","journal-title":"Cell Tissue Res"},{"issue":"1","key":"1555_CR32","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0306-4522(96)00280-1","volume":"75","author":"HC Liou","year":"1996","unstructured":"Liou HC, Yang RS, Fu WM (1996) Potentiation of spontaneous acetylcholine release from motor nerve terminals by glutamate in Xenopus tadpoles. Neuroscience 75(1):325\u2013331","journal-title":"Neuroscience"},{"issue":"9","key":"1555_CR33","doi-asserted-by":"crossref","first-page":"3200","DOI":"10.1523\/JNEUROSCI.20-09-03200.2000","volume":"20","author":"M Liu","year":"2000","unstructured":"Liu M, Kirchgessner AL (2000) Agonist- and reflex-evoked internalization of metabotropic glutamate receptor 5 in enteric neurons. J Neurosci 20(9):3200\u20133205","journal-title":"J Neurosci"},{"issue":"12","key":"1555_CR34","doi-asserted-by":"crossref","first-page":"4764","DOI":"10.1523\/JNEUROSCI.17-12-04764.1997","volume":"17","author":"MT Liu","year":"1997","unstructured":"Liu MT, Rothstein JD, Gershon MD, Kirchgessner AL (1997) Glutamatergic enteric neurons. J Neurosci 17(12):4764\u20134784","journal-title":"J Neurosci"},{"issue":"3","key":"1555_CR35","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0891-0618(96)00189-5","volume":"12","author":"PT Mann","year":"1997","unstructured":"Mann PT, Southwell BR, Young HM, Furness JB (1997) Appositions made by axons of descending interneurons in the guinea-pig small intestine, investigated by confocal microscopy. J Chem Neuroanat 12(3):151\u2013164","journal-title":"J Chem Neuroanat"},{"issue":"1","key":"1555_CR36","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1016\/j.neuroscience.2007.05.036","volume":"148","author":"JCG Marviz\u00f3n","year":"2007","unstructured":"Marviz\u00f3n JCG, P\u00e9rez OA, Song B, Chen W, Bunnett NW, Grady EF, Todd AJ (2007) Calcitonin receptor-like receptor and receptor activity modifying protein 1 in the rat dorsal horn: localization in glutamatergic presynaptic terminals containing opioids and adrenergic \u03b12 C receptors. Neuroscience 148(1):250\u2013265. doi: 10.1016\/j.neuroscience.2007.05.036","journal-title":"Neuroscience"},{"issue":"1","key":"1555_CR37","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1152\/jn.1998.79.1.379","volume":"79","author":"BA McCool","year":"1998","unstructured":"McCool BA, Pin J-P, Harpold MM, Brust PF, Stauderman KA, Lovinger DM (1998) Rat group I metabotropic glutamate receptors inhibit neuronal Ca2+ channels via multiple signal transduction pathways in HEK 293 cells. J Neurophysiol 79(1):379\u2013391","journal-title":"J Neurophysiol"},{"issue":"7","key":"1555_CR38","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1053\/gast.2001.24848","volume":"120","author":"JA McRoberts","year":"2001","unstructured":"McRoberts JA, Coutinho SV, Marvizon JC, Grady EF, Tognetto M, Sengupta JN, Ennes HS, Chaban VV, Amadesi S, Creminon C, Lanthorn T, Geppetti P, Bunnett NW, Mayer EA (2001) Role of peripheral N-methyl-d-aspartate (NMDA) receptors in visceral nociception in rats. Gastroenterology 120(7):1737\u20131748","journal-title":"Gastroenterology"},{"issue":"10","key":"1555_CR39","doi-asserted-by":"publisher","first-page":"e26128","DOI":"10.1371\/journal.pone.0026128","volume":"6","author":"I Nepliouev","year":"2011","unstructured":"Nepliouev I, Zhang Z-S, Stiber JA (2011) Effect of oxidative stress on Homer scaffolding proteins. PloS One 6(10):e26128. doi: 10.1371\/journal.pone.0026128","journal-title":"PloS One"},{"issue":"3","key":"1555_CR40","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0165-1838(87)90153-6","volume":"20","author":"WL Neuhuber","year":"1987","unstructured":"Neuhuber WL (1987) Sensory vagal innervation of the rat esophagus and cardia: a light and electron microscopic anterograde tracing study. J Auton Nerv Syst 20(3):243\u2013255","journal-title":"J Auton Nerv Syst"},{"key":"1555_CR41","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/978-1-4613-0579-8_9","volume-title":"The primary afferent neuron","author":"WL Neuhuber","year":"1990","unstructured":"Neuhuber WL, Clerc N (1990) Afferent innervation of the esophagus in cat and rat. In: Zenker W, Neuhuber WL. (eds) The primary afferent neuron. Plenum Press, New York, pp\u00a093\u2013107"},{"issue":"6","key":"1555_CR100","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1007\/s00418-016-1500-1","volume":"146","author":"WL Neuhuber","year":"2016","unstructured":"Neuhuber WL, W\u00f6rl J (2016) Enteric co-innervation of striated muscle in the esophagus: still enigmatic? Histochem Cell Biol 146(6):721\u2013735. doi: 10.1007\/s00418-016-1500-1","journal-title":"Histochem Cell Biol"},{"issue":"1","key":"1555_CR42","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/BF00354780","volume":"276","author":"WL Neuhuber","year":"1994","unstructured":"Neuhuber WL, W\u00f6rl J, Berthoud HR, Conte B (1994) NADPH-diaphorase-positive nerve fibers associated with motor endplates in the rat esophagus: new evidence for co-innervation of striated muscle by enteric neurons. Cell Tissue Res 276(1):23\u201330","journal-title":"Cell Tissue Res"},{"key":"1555_CR43","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/cne.900850204","volume":"85","author":"JF Nonidez","year":"1946","unstructured":"Nonidez JF (1946) Afferent nerves in the intermuscular plexus of the dog\u2019s oesophagus. J Comp Neurol 85:177\u2013189","journal-title":"J Comp Neurol"},{"issue":"3","key":"1555_CR44","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/S0959-4388(98)80062-7","volume":"8","author":"RJ O\u2019Brien","year":"1998","unstructured":"O\u2019Brien RJ, Lau L-F, Huganir RL (1998) Molecular mechanisms of glutamate receptor clustering at excitatory synapses. Curr Opin Neurobiol 8(3):364","journal-title":"Curr Opin Neurobiol"},{"issue":"2","key":"1555_CR45","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1053\/j.gastro.2004.11.062","volume":"128","author":"AJ Page","year":"2005","unstructured":"Page AJ, Young RL, Martin CM, Umaerus M, O\u2019Donnell TA, Cooper NJ, Coldwell JR, Hulander M, Mattsson JP, Lehmann A, Blackshaw LA (2005) Metabotropic glutamate receptors inhibit mechanosensitivity in vagal sensory neurons. Gastroenterology 128(2):402\u2013410","journal-title":"Gastroenterology"},{"issue":"4","key":"1555_CR46","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1007\/s00424-009-0664-0","volume":"458","author":"P Pouliquin","year":"2009","unstructured":"Pouliquin P, Pace S, Dulhunty A (2009) In vitro modulation of the cardiac ryanodine receptor activity by Homer1. Pflugers Arch Eur J Physiol 458(4):723\u2013732. doi: 10.1007\/s00424-009-0664-0","journal-title":"Pflugers Arch Eur J Physiol"},{"key":"1555_CR47","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1111\/j.1365-2982.2007.00990.x","volume":"20","author":"TL Powley","year":"2008","unstructured":"Powley TL, Wang XY, Fox EA, Phillips RJ, Liu LWC, Huizinga JD (2008) Ultrastructural evidence for communication betweenbintramuscular vagal mechanoreceptors and interstitial cells of Cajal in the rat fundus. Neurogastroenterol Motil 20:69\u201379. doi: 10.1111\/j.1365-2982.2007.00990.x","journal-title":"Neurogastroenterol Motil"},{"issue":"2","key":"1555_CR48","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s00441-003-0721-5","volume":"312","author":"M Raab","year":"2003","unstructured":"Raab M, Neuhuber WL (2003) Vesicular glutamate transporter 2 immunoreactivity in putative vagal mechanosensor terminals of mouse and rat esophagus: indication of a local effector function? Cell Tissue Res 312(2):141\u2013148","journal-title":"Cell Tissue Res"},{"issue":"5","key":"1555_CR49","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/s00418-004-0703-z","volume":"122","author":"M Raab","year":"2004","unstructured":"Raab M, Neuhuber WL (2004) Intraganglionic laminar endings and their relationships with neuronal and glial structures of myenteric ganglia in the esophagus of rat and mouse. Histochem Cell Biol 122(5):445\u2013459","journal-title":"Histochem Cell Biol"},{"issue":"8","key":"1555_CR50","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1369\/jhc.4A6582.2005","volume":"53","author":"M Raab","year":"2005","unstructured":"Raab M, Neuhuber WL (2005) Number and distribution of intraganglionic laminar endings in the mouse esophagus as demonstrated with two different immunohistochemical markers. J Histochem Cytochem 53(8):1023\u20131031","journal-title":"J Histochem Cytochem"},{"key":"1555_CR51","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0074-7696(07)56007-9","volume":"256","author":"M Raab","year":"2007","unstructured":"Raab M, Neuhuber WL (2007) Glutamatergic functions of primary afferent neurons with special emphasis on vagal afferents. Int Rev Cytol 256:223\u2013275","journal-title":"Int Rev Cytol"},{"issue":"2","key":"1555_CR52","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.neuroscience.2010.08.041","volume":"171","author":"M Raab","year":"2010","unstructured":"Raab M, Boeckers TM, Neuhuber WL (2010) Proline-rich synapse-associated protein-1 and 2 (ProSAP1\/Shank2 and ProSAP2\/Shank3)\u2013scaffolding proteins are also present in postsynaptic specializations of the peripheral nervous system. Neuroscience 171(2):421\u2013433. doi: 10.1016\/j.neuroscience.2010.08.041","journal-title":"Neuroscience"},{"issue":"36","key":"1555_CR53","doi-asserted-by":"publisher","first-page":"25953","DOI":"10.1074\/jbc.274.36.25953","volume":"274","author":"KW Roche","year":"1999","unstructured":"Roche KW, Tu JC, Petralia RS, Xiao B, Wenthold RJ, Worley PF (1999) Homer 1b regulates the trafficking of group I metabotropic glutamate receptors. J Biol Chem 274(36):25953\u201325957. doi: 10.1074\/jbc.274.36.25953","journal-title":"J Biol Chem"},{"key":"1555_CR54","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1159\/000144431","volume":"92","author":"J Rodrigo","year":"1975","unstructured":"Rodrigo J, Hernandez J, Vidal MA, Pedrosa JA (1975) Vegetative innervation of the esophagus. II. Intraganglionic laminar endings. Acta Anat 92:79\u2013100","journal-title":"Acta Anat"},{"issue":"1","key":"1555_CR55","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1159\/000145496","volume":"112","author":"J Rodrigo","year":"1982","unstructured":"Rodrigo J, de Felipe J, Robles-Chillida EM, Perez Anton JA, Mayo I, Gomez A (1982) Sensory vagal nature and anatomical access paths to esophagus laminar nerve endings in myenteric ganglia. Determination by surgical degeneration methods. Acta Anat (Basel) 112 (1):47\u201357","journal-title":"Acta Anat (Basel)"},{"issue":"4","key":"1555_CR56","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1111\/j.1365-2982.2011.01868.x","volume":"24","author":"WO Rohof","year":"2012","unstructured":"Rohof WO, Aronica E, Beaumont H, Troost D, Boeckxstaens GE (2012) Localization of mGluR5, GABAB, GABAA, and cannabinoid receptors on the vago-vagal reflex pathway responsible for transient lower esophageal sphincter relaxation in humans: an immunohistochemical study. Neurogastroenterol Motil 24(4):383\u2013173. doi: 10.1111\/j.1365-2982.2011.01868.x","journal-title":"Neurogastroenterol Motil"},{"issue":"12","key":"1555_CR57","doi-asserted-by":"publisher","first-page":"4312","DOI":"10.1096\/fj.11-186049","volume":"25","author":"M Salanova","year":"2011","unstructured":"Salanova M, Bortoloso E, Schiffl G, Gutsmann M, Belav\u00fd DL, Felsenberg D, Furlan S, Volpe P, Blottner D (2011) Expression and regulation of Homer in human skeletal muscle during neuromuscular junction adaptation to disuse and exercise. FASEB J 25(12):4312\u20134325. doi: 10.1096\/fj.11-186049","journal-title":"FASEB J"},{"issue":"9","key":"1555_CR58","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1002\/iub.1198","volume":"65","author":"M Salanova","year":"2013","unstructured":"Salanova M, Volpe P, Blottner D (2013) Homer protein family regulation in skeletal muscle and neuromuscular adaptation. IUBMB Life 65(9):769\u2013776. doi: 10.1002\/iub.1198","journal-title":"IUBMB Life"},{"issue":"2","key":"1555_CR59","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1006\/bbrc.2000.3948","volume":"279","author":"D Sandon\u00e0","year":"2000","unstructured":"Sandon\u00e0 D, Tibaldo E, Volpe P (2000) Evidence for the presence of two Homer 1 transcripts in skeletal and cardiac muscles. Biochem Biophys Res Commun 279(2):348\u2013353. doi: 10.1006\/bbrc.2000.3948","journal-title":"Biochem Biophys Res Commun"},{"issue":"2","key":"1555_CR60","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0006-8993(98)00893-2","volume":"809","author":"Q Sang","year":"1998","unstructured":"Sang Q, Young HM (1998) The origin and development of the vagal and spinal innervation of the external muscle of the mouse esophagus. Brain Res 809(2):253\u2013268","journal-title":"Brain Res"},{"issue":"1","key":"1555_CR61","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1152\/jn.2000.84.1.415","volume":"84","author":"NE Schwartz","year":"2000","unstructured":"Schwartz NE, Alford S (2000) Physiological activation of presynaptic metabotropic glutamate receptors increases intracellular calcium and glutamate release. J Neurophysiol 84(1):415\u2013427","journal-title":"J Neurophysiol"},{"issue":"2","key":"1555_CR62","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1186\/gb-2007-8-2-206","volume":"8","author":"Y Shiraishi-Yamaguchi","year":"2007","unstructured":"Shiraishi-Yamaguchi Y, Furuichi T (2007) The Homer family proteins. Genome Biol 8(2):206\u2013206. doi: 10.1186\/gb-2007-8-2-206","journal-title":"Genome Biol"},{"issue":"5","key":"1555_CR63","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1006\/jmbi.1999.3436","volume":"295","author":"M Soloviev","year":"2000","unstructured":"Soloviev M, Ciruela F, Chan W-Y, McIlhinney RAJ (2000a) Molecular characterisation of two structurally distinct groups of human homers, generated by extensive alternative splicing1. J Mol Biol 295(5):1185\u20131200. doi: 10.1006\/jmbi.1999.3436","journal-title":"J Mol Biol"},{"issue":"3","key":"1555_CR64","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1046\/j.1432-1327.2000.01078.x","volume":"267","author":"MM Soloviev","year":"2000","unstructured":"Soloviev MM, Ciruela F, Chan W-Y, McIlhinney RAJ (2000b) Mouse brain and muscle tissues constitutively express high levels of Homer proteins. Eur J Biochem 267(3):634\u2013639. doi: 10.1046\/j.1432-1327.2000.01078.x","journal-title":"Eur J Biochem"},{"issue":"2","key":"1555_CR65","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.ydbio.2005.06.030","volume":"287","author":"JA Stiber","year":"2005","unstructured":"Stiber JA, Tabatabaei N, Hawkins AF, Hawke T, Worley PF, Williams RS, Rosenberg P (2005) Homer modulates NFAT-dependent signaling during muscle differentiation. Dev Biol 287(2):213\u2013224. doi: 10.1016\/j.ydbio.2005.06.030","journal-title":"Dev Biol"},{"issue":"8","key":"1555_CR66","doi-asserted-by":"publisher","first-page":"2637","DOI":"10.1128\/MCB.01601-07","volume":"28","author":"JA Stiber","year":"2008","unstructured":"Stiber JA, Zhang ZS, Burch J, Eu JP, Zhang S, Truskey GA, Seth M, Yamaguchi N, Meissner G, Shah R, Worley PF, Williams RS, Rosenberg PB (2008) Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity. Mol Cell Biol 28(8):2637\u20132647. doi: 10.1128\/MCB.01601-07","journal-title":"Mol Cell Biol"},{"key":"1555_CR67","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.neuroscience.2014.01.066","volume":"266","author":"J-H Tao-Cheng","year":"2014","unstructured":"Tao-Cheng J-H, Thein S, Yang Y, Reese TS, Gallant PE (2014) Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation. Neuroscience 266:80\u201390. doi: 10.1016\/j.neuroscience.2014.01.066","journal-title":"Neuroscience"},{"issue":"5","key":"1555_CR68","doi-asserted-by":"crossref","first-page":"G992","DOI":"10.1152\/ajpgi.00118.2003","volume":"285","author":"Q Tong","year":"2003","unstructured":"Tong Q, Kirchgessner AL (2003) Localization and function of metabotropic glutamate receptor 8 in the enteric nervous system. Am J Physiol Gastrointest Liver Physiol 285(5):G992\u2013G1003","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"4","key":"1555_CR69","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/S0896-6273(00)80589-9","volume":"21","author":"JC Tu","year":"1998","unstructured":"Tu JC, Xiao B, Yuan JP, Lanahan AA, Leoffert K, Li M, Linden DJ, Worley PF (1998) Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors. Neuron 21(4):717\u2013726. doi: 10.1016\/S0896-6273(00)80589-9","journal-title":"Neuron"},{"issue":"3","key":"1555_CR70","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0896-6273(00)80810-7","volume":"23","author":"JC Tu","year":"1999","unstructured":"Tu JC, Xiao B, Naisbitt S, Yuan JP, Petralia RS, Brakeman P, Doan A, Aakalu VK, Lanahan AA, Sheng M, Worley PF (1999) Coupling of mGluR\/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins. Neuron 23(3):583\u2013592","journal-title":"Neuron"},{"issue":"3","key":"1555_CR71","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/S0022-3565(25)11127-0","volume":"261","author":"IH Ulus","year":"1992","unstructured":"Ulus IH, Buyukuysal RL, Wurtman RJ (1992) N-methyl-d-aspartate increases acetylcholine release from rat striatum and cortex: its effect is augmented by choline. J Pharmacol Exp Ther 261(3):1122\u20131128","journal-title":"J Pharmacol Exp Ther"},{"issue":"3\u20134","key":"1555_CR72","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1023\/A:1022833709448","volume":"28","author":"F Vyskocil","year":"2003","unstructured":"Vyskocil F (2003) Early postdenervation depolarization is controlled by acetylcholine and glutamate via nitric oxide regulation of the chloride transporter. Neurochem Res 28(3\u20134):575\u2013585","journal-title":"Neurochem Res"},{"issue":"7","key":"1555_CR73","doi-asserted-by":"crossref","first-page":"5781","DOI":"10.1074\/jbc.M311422200","volume":"279","author":"CW Ward","year":"2004","unstructured":"Ward CW, Feng W, Tu J, Pessah IN, Worley PK, Schneider MF (2004) Homer protein increases activation of Ca2 + sparks in permeabilized skeletal muscle. J Biol Chem 279(7):5781\u20135787","journal-title":"J Biol Chem"},{"issue":"3","key":"1555_CR74","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/S0143-4160(03)00112-X","volume":"34","author":"JH Westhoff","year":"2003","unstructured":"Westhoff JH, Hwang S-Y, Scott Duncan R, Ozawa F, Volpe P, Inokuchi K, Koulen P (2003) Vesl\/Homer proteins regulate ryanodine receptor type 2 function and intracellular calcium signaling. Cell Calcium 34(3):261\u2013269. doi: 10.1016\/S0143-4160(03)00112-X","journal-title":"Cell Calcium"},{"issue":"4 Pt 1","key":"1555_CR75","first-page":"G693","volume":"261","author":"JW Wiley","year":"1991","unstructured":"Wiley JW, Lu YX, Owyang C (1991) Evidence for a glutamatergic neural pathway in the myenteric plexus. Am J Physiol 261(4 Pt 1):G693\u2013G700","journal-title":"Am J Physiol"},{"issue":"2","key":"1555_CR76","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s00418-005-0764-7","volume":"123","author":"J W\u00f6rl","year":"2005","unstructured":"W\u00f6rl J, Neuhuber WL (2005) Enteric co-innervation of motor endplates in the esophagus: state of the art ten years after. Histochem Cell Biol 123(2):117\u2013130","journal-title":"Histochem Cell Biol"},{"issue":"3","key":"1555_CR77","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0165-1838(94)90169-4","volume":"49","author":"J W\u00f6rl","year":"1994","unstructured":"W\u00f6rl J, Mayer B, Neuhuber WL (1994) Nitrergic innervation of the rat esophagus: focus on motor endplates. J Auton Nerv Syst 49(3):227\u2013233","journal-title":"J Auton Nerv Syst"},{"issue":"4\u20135","key":"1555_CR78","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/j.ceca.2007.05.007","volume":"42","author":"PF Worley","year":"2007","unstructured":"Worley PF, Zeng W, Huang G, Kim JY, Shin DM, Kim MS, Yuan JP, Kiselyov K, Muallem S (2007) Homer proteins in Ca(2+) signaling by excitable and non-excitable cells. Cell Calcium 42(4\u20135):363\u2013371. doi: 10.1016\/j.ceca.2007.05.007","journal-title":"Cell Calcium"},{"issue":"4","key":"1555_CR79","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0896-6273(00)80588-7","volume":"21","author":"B Xiao","year":"1998","unstructured":"Xiao B, Tu JC, Petralia RS, Yuan JP, Doan A, Breder CD, Ruggiero A, Lanahan AA, Wenthold RJ, Worley PF (1998) Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. Neuron 21(4):707\u2013716","journal-title":"Neuron"},{"issue":"6","key":"1555_CR80","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1016\/S0092-8674(03)00716-5","volume":"114","author":"JP Yuan","year":"2003","unstructured":"Yuan JP, Kiselyov K, Shin DM, Chen J, Shcheynikov N, Kang SH, Dehoff MH, Schwarz MK, Seeburg PH, Muallem S, Worley PF (2003) Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell 114(6):777\u2013789. doi: 10.1016\/S0092-8674(03)00716-5","journal-title":"Cell"},{"issue":"2","key":"1555_CR81","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1111\/j.1748-1716.2011.02319.x","volume":"204","author":"JP Yuan","year":"2012","unstructured":"Yuan JP, Lee KP, Hong JH, Muallem S (2012) The closing and opening of TRPC channels by Homer1 and STIM1. Acta Physiol (Oxf) 204(2):238\u2013247. doi: 10.1111\/j.1748-1716.2011.02319.x","journal-title":"Acta Physiol (Oxf)"},{"issue":"16","key":"1555_CR82","doi-asserted-by":"crossref","first-page":"6249","DOI":"10.1523\/JNEUROSCI.20-16-06249.2000","volume":"20","author":"VP Zagorodnyuk","year":"2000","unstructured":"Zagorodnyuk VP, Brookes SJ (2000) Transduction sites of vagal mechanoreceptors in the guinea pig esophagus. J Neurosci 20(16):6249\u20136255","journal-title":"J Neurosci"},{"issue":"1","key":"1555_CR83","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1469-7793.2001.00255.x","volume":"534","author":"VP Zagorodnyuk","year":"2001","unstructured":"Zagorodnyuk VP, Chen BN, Brookes SJ (2001) Intraganglionic laminar endings are mechano-transduction sites of vagal tension receptors in the guinea-pig stomach. J Physiol 534(Pt 1):255\u2013268","journal-title":"J Physiol"},{"issue":"6","key":"1555_CR84","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/S0896-6273(00)80409-2","volume":"19","author":"EB Ziff","year":"1997","unstructured":"Ziff EB (1997) Enlightening the postsynaptic density. Neuron 19(6):1163\u20131174","journal-title":"Neuron"}],"container-title":["Histochemistry and Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00418-017-1555-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-017-1555-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-017-1555-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T16:32:56Z","timestamp":1750177976000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00418-017-1555-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,23]]},"references-count":85,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["1555"],"URL":"https:\/\/doi.org\/10.1007\/s00418-017-1555-7","relation":{},"ISSN":["0948-6143","1432-119X"],"issn-type":[{"type":"print","value":"0948-6143"},{"type":"electronic","value":"1432-119X"}],"subject":[],"published":{"date-parts":[[2017,3,23]]}}}