{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:12:42Z","timestamp":1792782762322,"version":"4.5.0"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2018,7,26]],"date-time":"2018-07-26T00:00:00Z","timestamp":1532563200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"FWF Austria","award":["PIR7"],"award-info":[{"award-number":["PIR7"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Histochem Cell Biol"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1007\/s00418-018-1699-0","type":"journal-article","created":{"date-parts":[[2018,7,25]],"date-time":"2018-07-25T20:59:31Z","timestamp":1532552371000},"page":"361-370","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":161,"title":["Human trophoblast invasion: new and unexpected routes and functions"],"prefix":"10.1007","volume":"150","author":[{"given":"Gerit","family":"Moser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Windsperger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Pollheimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana Chuva","family":"de Sousa Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4814-2158","authenticated-orcid":false,"given":"Berthold","family":"Huppertz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,7,26]]},"reference":[{"key":"1699_CR1","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1071\/RD01063","volume":"13","author":"WR Allen","year":"2001","unstructured":"Allen WR, Stewart F (2001) Equine placentation. Reprod Fertil Dev 13:623\u2013634","journal-title":"Reprod Fertil Dev"},{"key":"1699_CR2","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1002\/path.1926","volume":"208","author":"E Ball","year":"2006","unstructured":"Ball E, Robson SC, Ayis S, Lyall F, Bulmer JN (2006) Early embryonic demise: no evidence of abnormal spiral artery transformation or trophoblast invasion. J Pathol 208:528\u2013534","journal-title":"J Pathol"},{"key":"1699_CR3","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/978-3-642-23941-0_9","volume-title":"Pathology of the human placenta","author":"K Benirschke","year":"2012","unstructured":"Benirschke K, Burton GJ, Baergen RN (2012) Nonvillous parts and trophoblast invasion. In: Pathology of the human placenta. Springer, New York, pp\u00a0157\u2013240"},{"key":"1699_CR4","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1038\/211988a0","volume":"211","author":"WD Billington","year":"1966","unstructured":"Billington WD (1966) Vascular migration of transplanted trophoblast in the golden hamster. Nature 211:988\u2013989","journal-title":"Nature"},{"key":"1699_CR5","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1177\/1933719116632922","volume":"23","author":"AD Bolnick","year":"2016","unstructured":"Bolnick AD, Fritz R, Jain C, Kadam L, Bolnick JM, Kilburn BA, Singh M, Diamond MP, Drewlo S, Armant DR (2016a) Trophoblast retrieval and isolation from the cervix for noninvasive, first trimester, fetal gender determination in a carrier of congenital adrenal hyperplasia. Reprod Sci Thousand Oaks Calif 23:717\u2013722","journal-title":"Reprod Sci Thousand Oaks Calif"},{"key":"1699_CR6","doi-asserted-by":"publisher","first-page":"32382","DOI":"10.1038\/srep32382","volume":"6","author":"JM Bolnick","year":"2016","unstructured":"Bolnick JM, Kohan-Ghadr H-R, Fritz R, Bolnick AD, Kilburn BA, Diamond MP, Armant DR, Drewlo S (2016b) Altered biomarkers in trophoblast cells obtained noninvasively prior to clinical manifestation of perinatal disease. Sci Rep 6:32382","journal-title":"Sci Rep"},{"key":"1699_CR7","doi-asserted-by":"publisher","first-page":"1416","DOI":"10.1067\/mob.2002.127305","volume":"187","author":"JJ Brosens","year":"2002","unstructured":"Brosens JJ, Pijnenborg R, Brosens IA (2002) The myometrial junctional zone spiral arteries in normal and abnormal pregnancies: a review of the literature. Am J Obstet Gynecol 187:1416\u20131423","journal-title":"Am J Obstet Gynecol"},{"key":"1699_CR8","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.placenta.2017.06.007","volume":"60","author":"GJ Burton","year":"2017","unstructured":"Burton GJ, Jauniaux E (2017) The cytotrophoblastic shell and complications of pregnancy. Placenta 60:134\u2013139","journal-title":"Placenta"},{"key":"1699_CR9","doi-asserted-by":"publisher","first-page":"2954","DOI":"10.1210\/jcem.87.6.8563","volume":"87","author":"GJ Burton","year":"2002","unstructured":"Burton GJ, Watson AL, Hempstock J, Skepper JN, Jauniaux E (2002) Uterine glands provide histiotrophic nutrition for the human fetus during the first trimester of pregnancy. J Clin Endocrinol Metab 87:2954\u20132959","journal-title":"J Clin Endocrinol Metab"},{"key":"1699_CR10","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1016\/j.placenta.2009.02.009","volume":"30","author":"GJ Burton","year":"2009","unstructured":"Burton GJ, Woods AW, Jauniaux E, Kingdom JCP (2009) Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy. Placenta 30:473\u2013482","journal-title":"Placenta"},{"key":"1699_CR11","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1126\/science.aam8940","volume":"357","author":"J Cao","year":"2017","unstructured":"Cao J, Packer JS, Ramani V, Cusanovich DA, Huynh C, Daza R, Qiu X, Lee C, Furlan SN, Steemers FJ et al (2017) Comprehensive single-cell transcriptional profiling of a multicellular organism. Science 357:661\u2013667","journal-title":"Science"},{"key":"1699_CR12","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.jri.2011.01.002","volume":"88","author":"LW Chamley","year":"2011","unstructured":"Chamley LW, Chen Q, Ding J, Stone PR, Abumaree M (2011) Trophoblast deportation: just a waste disposal system or antigen sharing? J Reprod Immunol 88:99\u2013105","journal-title":"J Reprod Immunol"},{"issue":"Suppl","key":"1699_CR13","doi-asserted-by":"publisher","first-page":"S74","DOI":"10.1016\/j.placenta.2013.10.014","volume":"35","author":"LW Chamley","year":"2014","unstructured":"Chamley LW, Holland OJ, Chen Q, Viall CA, Stone PR, Abumaree M (2014) Review: where is the maternofetal interface? Placenta 35(Suppl):S74\u2013S80","journal-title":"Placenta"},{"key":"1699_CR14","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/S0301-2115(99)00281-X","volume":"92","author":"J Delmis","year":"2000","unstructured":"Delmis J, Pfeifer D, Ivanisevic M, Forko JI, Hlupic L (2000) Sudden death from trophoblastic embolism in pregnancy. Eur J Obstet Gynecol Reprod Biol 92:225\u2013227","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"Suppl 1","key":"1699_CR15","doi-asserted-by":"publisher","first-page":"S27","DOI":"10.1016\/j.placenta.2017.04.021","volume":"60","author":"S Drewlo","year":"2017","unstructured":"Drewlo S, Armant DR (2017) Quo vadis, trophoblast? Exploring the new ways of an old cell lineage. Placenta 60(Suppl 1):S27\u2013S31","journal-title":"Placenta"},{"key":"1699_CR16","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1093\/humrep\/17.4.1072","volume":"17","author":"PM Emmer","year":"2002","unstructured":"Emmer PM, Steegers EAP, Kerstens HMJ, Bulten J, Nelen WLDM, Boer K, Joosten I (2002) Altered phenotype of HLA-G expressing trophoblast and decidual natural killer cells in pathological pregnancies. Hum Reprod 17:1072\u20131080","journal-title":"Hum Reprod"},{"key":"1699_CR17","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.placenta.2004.11.007","volume":"27","author":"D Goswami","year":"2006","unstructured":"Goswami D, Tannetta DS, Magee LA, Fuchisawa A, Redman CWG, Sargent IL, von Dadelszen P (2006) Excess syncytiotrophoblast microparticle shedding is a feature of early-onset pre-eclampsia, but not normotensive intrauterine growth restriction. Placenta 27:56\u201361","journal-title":"Placenta"},{"key":"1699_CR18","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1038\/nmeth.4407","volume":"14","author":"N Habib","year":"2017","unstructured":"Habib N, Avraham-Davidi I, Basu A, Burks T, Shekhar K, Hofree M, Choudhury SR, Aguet F, Gelfand E, Ardlie K et al (2017) Massively parallel single-nucleus RNA-seq with DroNc-sEq. Nat Methods 14:955\u2013958","journal-title":"Nat Methods"},{"key":"1699_CR19","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.jri.2011.05.001","volume":"90","author":"A Hammer","year":"2011","unstructured":"Hammer A (2011) Immunological regulation of trophoblast invasion. J Reprod Immunol 90:21\u201328","journal-title":"J Reprod Immunol"},{"issue":"Suppl","key":"1699_CR20","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.placenta.2009.12.012","volume":"31","author":"LK Harris","year":"2010","unstructured":"Harris LK (2010) Review: trophoblast-vascular cell interactions in early pregnancy: how to remodel a vessel. Placenta 31(Suppl):93\u201398","journal-title":"Placenta"},{"key":"1699_CR21","doi-asserted-by":"publisher","first-page":"e0169849","DOI":"10.1371\/journal.pone.0169849","volume":"12","author":"N He","year":"2017","unstructured":"He N, van Iperen L, de Jong D, Szuhai K, Helmerhorst FM, van der Westerlaken LAJ, Lopes SM (2017) Human extravillous trophoblasts penetrate decidual veins and lymphatics before remodeling spiral arteries during early pregnancy. PLoS One 12:e0169849","journal-title":"PLoS One"},{"issue":"Suppl","key":"1699_CR22","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.placenta.2009.12.001","volume":"31","author":"B Huppertz","year":"2010","unstructured":"Huppertz B (2010) IFPA award in placentology lecture: biology of the placental syncytiotrophoblast\u2013myths and facts. Placenta 31(Suppl):75\u201381","journal-title":"Placenta"},{"key":"1699_CR23","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/s004410050987","volume":"291","author":"B Huppertz","year":"1998","unstructured":"Huppertz B, Kertschanska S, Demir AY, Frank HG, Kaufmann P (1998a) Immunohistochemistry of matrix metalloproteinases (MMP), their substrates, and their inhibitors (TIMP) during trophoblast invasion in the human placenta. Cell Tissue Res 291:133\u2013148","journal-title":"Cell Tissue Res"},{"key":"1699_CR24","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1007\/s004180050311","volume":"110","author":"B Huppertz","year":"1998","unstructured":"Huppertz B, Frank HG, Kingdom JC, Reister F, Kaufmann P (1998b) Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta. Histochem Cell Biol 110:495\u2013508","journal-title":"Histochem Cell Biol"},{"key":"1699_CR25","first-page":"62","volume":"20","author":"FA Ikle","year":"1964","unstructured":"Ikle FA (1964) Dissemination of syncytial trophoblast cells in the maternal blood stream during pregnancy. Bull Schweiz Akad Med Wiss 20:62\u201372","journal-title":"Bull Schweiz Akad Med Wiss"},{"key":"1699_CR26","doi-asserted-by":"publisher","first-page":"2111","DOI":"10.1016\/S0002-9440(10)64849-3","volume":"157","author":"E Jauniaux","year":"2000","unstructured":"Jauniaux E, Watson AL, Hempstock J, Bao Y-P, Skepper JN, Burton GJ (2000) Onset of maternal arterial blood flow and placental oxidative stress. Am J Pathol 157:2111\u20132122","journal-title":"Am J Pathol"},{"key":"1699_CR27","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1053\/plac.1999.0422","volume":"20","author":"M Johansen","year":"1999","unstructured":"Johansen M, Redman CW, Wilkins T, Sargent IL (1999) Trophoblast deportation in human pregnancy\u2014its relevance for pre-eclampsia. Placenta 20:531\u2013539","journal-title":"Placenta"},{"key":"1699_CR28","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/S0940-9602(96)80102-6","volume":"178","author":"P Kaufmann","year":"1996","unstructured":"Kaufmann P, Huppertz B, Frank HG (1996) The fibrinoids of the human placenta: origin, composition and functional relevance. Ann Anat 178:485\u2013501","journal-title":"Ann Anat"},{"key":"1699_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1095\/biolreprod.102.014977","volume":"69","author":"P Kaufmann","year":"2003","unstructured":"Kaufmann P, Black S, Huppertz B (2003) Endovascular trophoblast invasion: implications for the pathogenesis of intrauterine growth retardation and preeclampsia. Biol Reprod 69:1\u20137","journal-title":"Biol Reprod"},{"key":"1699_CR30","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1007\/s00418-002-0396-0","volume":"117","author":"B Kemp","year":"2002","unstructured":"Kemp B, Kertschanska S, Kadyrov M, Rath W, Kaufmann P, Huppertz B (2002) Invasive depth of extravillous trophoblast correlates with cellular phenotype: a comparison of intra- and extrauterine implantation sites. Histochem Cell Biol 117:401\u2013414","journal-title":"Histochem Cell Biol"},{"key":"1699_CR31","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.fertnstert.2010.05.045","volume":"95","author":"B Kemp","year":"2011","unstructured":"Kemp B, Schmitz S, Krusche CA, Rath W, von Rango U (2011) Dendritic cells are equally distributed in intrauterine and tubal ectopic pregnancies. Fertil Steril 95:28\u201332","journal-title":"Fertil Steril"},{"key":"1699_CR32","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1016\/j.placenta.2015.08.002","volume":"36","author":"P Li","year":"2015","unstructured":"Li P, Peng H, Lu W-H, Shuai H-L, Zha Q-B, Yeung C-K, Li H, Wang L-J, Lee KK, Zhu W-J et al (2015) Role of Slit2\/Robo1 in trophoblast invasion and vascular remodeling during ectopic tubal pregnancy. Placenta 36:1087\u20131094","journal-title":"Placenta"},{"key":"1699_CR33","doi-asserted-by":"crossref","first-page":"3771","DOI":"10.4049\/jimmunol.154.8.3771","volume":"154","author":"MT McMaster","year":"1995","unstructured":"McMaster MT, Librach CL, Zhou Y, Lim KH, Janatpour MJ, DeMars R, Kovats S, Damsky C, Fisher SJ (1995) Human placental HLA-G expression is restricted to differentiated cytotrophoblasts. J Immunol 154:3771\u20133778","journal-title":"J Immunol"},{"key":"1699_CR34","doi-asserted-by":"publisher","first-page":"e111874","DOI":"10.1371\/journal.pone.0111874","volume":"9","author":"A Mezger","year":"2014","unstructured":"Mezger A, \u00d6hrmalm C, Herthnek D, Blomberg J, Nilsson M (2014) Detection of rotavirus using padlock probes and rolling circle amplification. PloS One 9:e111874","journal-title":"PloS One"},{"key":"1699_CR35","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1111\/j.1471-0528.1990.tb02468.x","volume":"97","author":"MZ Michel","year":"1990","unstructured":"Michel MZ, Khong TY, Clark DA, Beard RW (1990) A morphological and immunological study of human placental bed biopsies in miscarriage. Br J Obstet Gynaecol 97:984\u2013988","journal-title":"Br J Obstet Gynaecol"},{"key":"1699_CR36","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.placenta.2017.02.007","volume":"56","author":"G Moser","year":"2017","unstructured":"Moser G, Huppertz B (2017) Implantation and extravillous trophoblast invasion: from rare archival specimens to modern biobanking. Placenta 56:19\u201326","journal-title":"Placenta"},{"key":"1699_CR37","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1093\/humrep\/deq035","volume":"25","author":"G Moser","year":"2010","unstructured":"Moser G, Gauster M, Orendi K, Glasner A, Theuerkauf R, Huppertz B (2010) Endoglandular trophoblast, an alternative route of trophoblast invasion? Analysis with novel confrontation co-culture models. Hum Reprod 25:1127\u20131136","journal-title":"Hum Reprod"},{"key":"1699_CR38","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.placenta.2010.11.008","volume":"32","author":"G Moser","year":"2011","unstructured":"Moser G, Orendi K, Gauster M, Siwetz M, Helige C, Huppertz B (2011) The art of identification of extravillous trophoblast. Placenta 32:197\u2013199","journal-title":"Placenta"},{"key":"1699_CR39","doi-asserted-by":"publisher","first-page":"2747","DOI":"10.1093\/humrep\/dev266","volume":"30","author":"G Moser","year":"2015","unstructured":"Moser G, Weiss G, Gauster M, Sundl M, Huppertz B (2015) Evidence from the very beginning: endoglandular trophoblasts penetrate and replace uterine glands in situ and in vitro. Hum Reprod 30:2747\u20132757","journal-title":"Hum Reprod"},{"key":"1699_CR40","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s00418-016-1509-5","volume":"147","author":"G Moser","year":"2017","unstructured":"Moser G, Weiss G, Sundl M, Gauster M, Siwetz M, Lang-Olip I, Huppertz B (2017) Extravillous trophoblasts invade more than uterine arteries: evidence for the invasion of uterine veins. Histochem Cell Biol 147:353\u2013366","journal-title":"Histochem Cell Biol"},{"key":"1699_CR41","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1093\/humupd\/dmy008","volume":"24","author":"G Moser","year":"2018","unstructured":"Moser G, Drewlo S, Huppertz B, Armant DR (2018) Trophoblast retrieval and isolation from the cervix: origins of cervical trophoblasts and their potential value for risk assessment of ongoing pregnancies. Hum Reprod Update 24:484\u2013496","journal-title":"Hum Reprod Update"},{"key":"1699_CR42","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1093\/humrep\/den296","volume":"24","author":"M Plaisier","year":"2009","unstructured":"Plaisier M, Dennert I, Rost E, Koolwijk P, van Hinsbergh VWM, Helmerhorst FM (2009) Decidual vascularization and the expression of angiogenic growth factors and proteases in first trimester spontaneous abortions. Hum Reprod 24:185\u2013197","journal-title":"Hum Reprod"},{"key":"1699_CR43","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1093\/humrep\/den348","volume":"24","author":"S Quenby","year":"2009","unstructured":"Quenby S, Nik H, Innes B, Lash G, Turner M, Drury J, Bulmer J (2009) Uterine natural killer cells and angiogenesis in recurrent reproductive failure. Hum Reprod 24:45\u201354","journal-title":"Hum Reprod"},{"key":"1699_CR44","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1111\/j.1749-6632.1959.tb44586.x","volume":"75","author":"EM Ramsey","year":"1959","unstructured":"Ramsey EM (1959) Vascular adaptations of the uterus to pregnancy. Ann N Y Acad Sci 75:726\u2013745","journal-title":"Ann N Y Acad Sci"},{"key":"1699_CR45","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1097\/00004347-198706000-00005","volume":"6","author":"S Randall","year":"1987","unstructured":"Randall S, Buckley CH, Fox H (1987) Placentation in the fallopian tube. Int J Gynecol Pathol 6:132\u2013139","journal-title":"Int J Gynecol Pathol"},{"key":"1699_CR46","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1053\/plac.2000.0560","volume":"21","author":"CW Redman","year":"2000","unstructured":"Redman CW, Sargent IL (2000) Placental debris, oxidative stress and pre-eclampsia. Placenta 21:597\u2013602","journal-title":"Placenta"},{"key":"1699_CR47","doi-asserted-by":"publisher","first-page":"2382","DOI":"10.1093\/humrep\/dex301","volume":"32","author":"VHJ Roberts","year":"2017","unstructured":"Roberts VHJ, Morgan TK, Bednarek P, Morita M, Burton GJ, Lo JO, Frias AE (2017) Early first trimester uteroplacental flow and the progressive disintegration of spiral artery plugs: new insights from contrast-enhanced ultrasound and tissue histopathology. Hum Reprod 32:2382\u20132393","journal-title":"Hum Reprod"},{"key":"1699_CR48","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1186\/1479-5876-12-204","volume":"12","author":"S Sarker","year":"2014","unstructured":"Sarker S, Scholz-Romero K, Perez A, Illanes SE, Mitchell MD, Rice GE, Salomon C (2014) Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. J Transl Med 12:204","journal-title":"J Transl Med"},{"key":"1699_CR49","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1093\/humrep\/17.4.1067","volume":"17","author":"NJ Sebire","year":"2002","unstructured":"Sebire NJ, Fox H, Backos M, Rai R, Paterson C, Regan L (2002) Defective endovascular trophoblast invasion in primary antiphospholipid antibody syndrome-associated early pregnancy failure. Hum Reprod 17:1067\u20131071","journal-title":"Hum Reprod"},{"key":"1699_CR50","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1038\/labinvest.2015.159","volume":"96","author":"M Siwetz","year":"2016","unstructured":"Siwetz M, Blaschitz A, El-Heliebi A, Hiden U, Desoye G, Huppertz B, Gauster M (2016) TNF-\u03b1 alters the inflammatory secretion profile of human first trimester placenta. Lab Investig 96:428\u2013438","journal-title":"Lab Investig"},{"key":"1699_CR51","doi-asserted-by":"publisher","first-page":"1628","DOI":"10.1093\/humrep\/14.6.1628","volume":"14","author":"B Vailh\u00e9","year":"1999","unstructured":"Vailh\u00e9 B, Dietl J, Kapp M, Toth B, Arck P (1999) Increased blood vessel density in decidua parietalis is associated with spontaneous human first trimester abortion. Hum Reprod 14:1628\u20131634","journal-title":"Hum Reprod"},{"key":"1699_CR52","first-page":"323","volume":"18","author":"SC Putte van der","year":"1980","unstructured":"van der Putte SC, van Limborgh J (1980) The embryonic development of the main lymphatics in man. Acta Morphol Neerl Scand 18:323\u2013335","journal-title":"Acta Morphol Neerl Scand"},{"key":"1699_CR53","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1007\/s00418-016-1474-z","volume":"146","author":"G Weiss","year":"2016","unstructured":"Weiss G, Sundl M, Glasner A, Huppertz B, Moser G (2016) The trophoblast plug during early pregnancy: a deeper insight. Histochem Cell Biol 146:749\u2013756","journal-title":"Histochem Cell Biol"},{"key":"1699_CR54","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1093\/humrep\/dex058","volume":"32","author":"K Windsperger","year":"2017","unstructured":"Windsperger K, Dekan S, Pils S, Golletz C, Kunihs V, Fiala C, Kristiansen G, Kn\u00f6fler M, Pollheimer J (2017) Extravillous trophoblast invasion of venous as well as lymphatic vessels is altered in idiopathic, recurrent, spontaneous abortions. Hum Reprod 32:1208\u20131217","journal-title":"Hum Reprod"}],"container-title":["Histochemistry and Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00418-018-1699-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-018-1699-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-018-1699-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T19:33:35Z","timestamp":1693769615000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00418-018-1699-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,26]]},"references-count":54,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["1699"],"URL":"https:\/\/doi.org\/10.1007\/s00418-018-1699-0","relation":{},"ISSN":["0948-6143","1432-119X"],"issn-type":[{"value":"0948-6143","type":"print"},{"value":"1432-119X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,26]]},"assertion":[{"value":"20 July 2018","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2018","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"No competing financial interests exist.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}