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Fifty-four male albino Wistar rats were divided into nine groups of six animals each. No treatment or surgery was applied to the control (CONT) group. The sciatic nerve was crushed for 5\u00a0s in the short-term injury (STI) and for 60\u00a0s in the long-term injury (LTI) groups. In the STI\u2009+\u2009BZ group and the LTI\u2009+\u2009BZ group, the rats received 25\u00a0mg\/kg\/day of BZ via oral gavage for 28\u00a0days. In the STI\u2009+\u2009ES and LTI\u2009+\u2009ES groups, a 3-V current was applied for 20\u00a0min daily for 28\u00a0days. In the STI\u2009+\u2009BZ\u2009+\u2009ES group and the LTI\u2009+\u2009BZ\u2009+\u2009ES groups, 3-V ES was applied for 20\u00a0min per day for 28\u00a0days following oral administration of BZ at 25\u00a0mg\/kg\/day for 28\u00a0days. All groups were subjected to electrophysiological, electron microscopic, stereological, and statistical analyses. The stereological analyses revealed a significant increases in the numbers of myelinated axons in the STI\u2009+\u2009ES groups compared with the STI (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.01). BZ treatment yielded no significant differences in the numbers of myelinated axons in the groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&gt;\u20090.05). Histological evaluation of the STI and LTI groups showed that ES and BZ treatment positively affect the histological structure of the nerve.\n                  <\/jats:p>","DOI":"10.1007\/s00418-025-02380-7","type":"journal-article","created":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T03:03:42Z","timestamp":1746068622000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The effects of benzimidazole and electrical stimulation on peripheral nerve regeneration after short- and long-term injury"],"prefix":"10.1007","volume":"163","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5359-1823","authenticated-orcid":false,"given":"Abubaker El","family":"Elhaj","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1424-501X","authenticated-orcid":false,"given":"Abdalla Ahmed Eldaw","family":"Elamin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1477-5002","authenticated-orcid":false,"given":"S\u00fcleyman","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"key":"2380_CR1","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1002\/(sici)1097-4598(199910)22:10","volume":"22","author":"WF Agnew","year":"1999","unstructured":"Agnew WF, Mccreery DB, Yuen TG, Bullara LA (1999) Evolution and resolution of stimulation-induced axonal injury in peripheral nerve. 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