{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T04:57:51Z","timestamp":1793163471031,"version":"4.5.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T00:00:00Z","timestamp":1775347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T00:00:00Z","timestamp":1775347200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Histochem Cell Biol"],"DOI":"10.1007\/s00418-026-02464-y","type":"journal-article","created":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T15:44:56Z","timestamp":1775403896000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Targeting SAT1 alleviates high glucose-induced tubular ferroptosis and fibrosis: implications for diabetic kidney disease"],"prefix":"10.1007","volume":"164","author":[{"given":"Yingqi","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunhua","family":"Di","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,5]]},"reference":[{"key":"2464_CR1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/360438","author":"A Ayala","year":"2014","unstructured":"Ayala A, Mu\u00f1oz MF, Arg\u00fcelles S (2014) Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal. Oxid Med Cell Longev. https:\/\/doi.org\/10.1155\/2014\/360438","journal-title":"Oxid Med Cell Longev"},{"issue":"11","key":"2464_CR2","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1261\/rna.078796.121","volume":"27","author":"M Baker","year":"2021","unstructured":"Baker M, Petasny M, Taqatqa N, Bentata M, Kay G, Engal E et al (2021) KDM3A regulates alternative splicing of cell-cycle genes following DNA damage. RNA 27(11):1353\u20131362. https:\/\/doi.org\/10.1261\/rna.078796.121","journal-title":"RNA"},{"issue":"6","key":"2464_CR3","doi-asserted-by":"publisher","first-page":"1615","DOI":"10.2337\/diabetes.54.6.1615","volume":"54","author":"M Brownlee","year":"2005","unstructured":"Brownlee M (2005) The pathobiology of diabetic complications: a unifying mechanism. Diabetes 54(6):1615\u20131625. https:\/\/doi.org\/10.2337\/diabetes.54.6.1615","journal-title":"Diabetes"},{"issue":"1","key":"2464_CR4","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1039\/c7fo00983f","volume":"9","author":"Z Chen","year":"2018","unstructured":"Chen Z, Wang C, Pan Y, Gao X, Chen H (2018) Hypoglycemic and hypolipidemic effects of anthocyanins extract from black soybean seed coat in high fat diet and streptozotocin-induced diabetic mice. Food Funct 9(1):426\u2013439. https:\/\/doi.org\/10.1039\/c7fo00983f","journal-title":"Food Funct"},{"issue":"5","key":"2464_CR5","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","volume":"149","author":"SJ Dixon","year":"2012","unstructured":"Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE et al (2012) Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 149(5):1060\u20131072. https:\/\/doi.org\/10.1016\/j.cell.2012.03.042","journal-title":"Cell"},{"key":"2464_CR6","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.626390","volume":"12","author":"X Feng","year":"2021","unstructured":"Feng X, Wang S, Sun Z, Dong H, Yu H, Huang M et al (2021) Ferroptosis enhanced diabetic renal tubular injury via HIF-1\u03b1\/HO-1 pathway in db\/db mice. Front Endocrinol (Lausanne) 12:626390. https:\/\/doi.org\/10.3389\/fendo.2021.626390","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"2464_CR7","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1142\/s0192415x23500465","volume":"51","author":"Q Feng","year":"2023","unstructured":"Feng Q, Yang Y, Qiao Y, Zheng Y, Yu X, Liu F et al (2023) Quercetin ameliorates diabetic kidney injury by inhibiting ferroptosis via activating Nrf2\/HO-1 signaling pathway. Am J Chin Med 51(4):997\u20131018. https:\/\/doi.org\/10.1142\/s0192415x23500465","journal-title":"Am J Chin Med"},{"issue":"5","key":"2464_CR8","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1038\/nrneph.2018.9","volume":"14","author":"JM Forbes","year":"2018","unstructured":"Forbes JM, Thorburn DR (2018) Mitochondrial dysfunction in diabetic kidney disease. Nat Rev Nephrol 14(5):291\u2013312. https:\/\/doi.org\/10.1038\/nrneph.2018.9","journal-title":"Nat Rev Nephrol"},{"issue":"12","key":"2464_CR9","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1038\/ncb3064","volume":"16","author":"JP Friedmann Angeli","year":"2014","unstructured":"Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ et al (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol 16(12):1180\u20131191. https:\/\/doi.org\/10.1038\/ncb3064","journal-title":"Nat Cell Biol"},{"key":"2464_CR10","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.redox.2018.02.013","volume":"16","author":"Y Han","year":"2018","unstructured":"Han Y, Xu X, Tang C, Gao P, Chen X, Xiong X et al (2018) Reactive oxygen species promote tubular injury in diabetic nephropathy: the role of the mitochondrial ROS-TXNIP-NLRP3 biological axis. Redox Biol 16:32\u201346. https:\/\/doi.org\/10.1016\/j.redox.2018.02.013","journal-title":"Redox Biol"},{"key":"2464_CR11","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.68603","author":"S Ide","year":"2021","unstructured":"Ide S, Kobayashi Y, Ide K, Strausser SA, Abe K, Herbek S et al (2021) Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair. Elife. https:\/\/doi.org\/10.7554\/eLife.68603","journal-title":"Elife"},{"issue":"4","key":"2464_CR12","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1038\/s41580-020-00324-8","volume":"22","author":"X Jiang","year":"2021","unstructured":"Jiang X, Stockwell BR, Conrad M (2021) Ferroptosis: mechanisms, biology and role in disease. Nat Rev Mol Cell Biol 22(4):266\u2013282. https:\/\/doi.org\/10.1038\/s41580-020-00324-8","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2464_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2022.112892","author":"T Jin","year":"2022","unstructured":"Jin T, Chen C (2022) Umbelliferone delays the progression of diabetic nephropathy by inhibiting ferroptosis through activation of the Nrf-2\/HO-1 pathway. Food Chem Toxicol. https:\/\/doi.org\/10.1016\/j.fct.2022.112892","journal-title":"Food Chem Toxicol"},{"key":"2464_CR14","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/j.freeradbiomed.2018.05.074","volume":"133","author":"R Kang","year":"2019","unstructured":"Kang R, Kroemer G, Tang D (2019) The tumor suppressor protein p53 and the ferroptosis network. Free Radic Biol Med 133:162\u2013168. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2018.05.074","journal-title":"Free Radic Biol Med"},{"issue":"1","key":"2464_CR15","doi-asserted-by":"publisher","first-page":"4","DOI":"10.3181\/0705-mr-134","volume":"233","author":"YS Kanwar","year":"2008","unstructured":"Kanwar YS, Wada J, Sun L, Xie P, Wallner EI, Chen S et al (2008) Diabetic nephropathy: mechanisms of renal disease progression. Exp Biol Med (Maywood) 233(1):4\u201311. https:\/\/doi.org\/10.3181\/0705-mr-134","journal-title":"Exp Biol Med (Maywood)"},{"issue":"2","key":"2464_CR16","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-03452-x","volume":"12","author":"S Kim","year":"2021","unstructured":"Kim S, Kang SW, Joo J, Han SH, Shin H, Nam BY et al (2021) Characterization of ferroptosis in kidney tubular cell death under diabetic conditions. Cell Death Dis 12(2):160. https:\/\/doi.org\/10.1038\/s41419-021-03452-x","journal-title":"Cell Death Dis"},{"issue":"7495","key":"2464_CR17","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1038\/nature13198","volume":"508","author":"D Kraus","year":"2014","unstructured":"Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT et al (2014) Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature 508(7495):258\u2013262. https:\/\/doi.org\/10.1038\/nature13198","journal-title":"Nature"},{"key":"2464_CR18","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/j.freeradbiomed.2020.10.323","volume":"162","author":"S Li","year":"2021","unstructured":"Li S, Zheng L, Zhang J, Liu X, Wu Z (2021) Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy. Free Radic Biol Med 162:435\u2013449. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2020.10.323","journal-title":"Free Radic Biol Med"},{"key":"2464_CR19","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1294317","volume":"14","author":"J Li","year":"2023","unstructured":"Li J, Li L, Zhang Z, Chen P, Shu H, Yang C et al (2023) Ferroptosis: an important player in the inflammatory response in diabetic nephropathy. Front Immunol 14:1294317. https:\/\/doi.org\/10.3389\/fimmu.2023.1294317","journal-title":"Front Immunol"},{"issue":"6","key":"2464_CR20","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-024-06780-w","volume":"15","author":"X Li","year":"2024","unstructured":"Li X, Ma TK, Wang P, Shi H, Hai S, Qin Y et al (2024) HOXD10 attenuates renal fibrosis by inhibiting NOX4-induced ferroptosis. Cell Death Dis 15(6):398. https:\/\/doi.org\/10.1038\/s41419-024-06780-w","journal-title":"Cell Death Dis"},{"issue":"12","key":"2464_CR21","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1038\/nrneph.2011.149","volume":"7","author":"Y Liu","year":"2011","unstructured":"Liu Y (2011) Cellular and molecular mechanisms of renal fibrosis. Nat Rev Nephrol 7(12):684\u2013696. https:\/\/doi.org\/10.1038\/nrneph.2011.149","journal-title":"Nat Rev Nephrol"},{"key":"2464_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2022.102260","author":"L Liu","year":"2022","unstructured":"Liu L, Bai F, Song H, Xiao R, Wang Y, Yang H et al (2022) Upregulation of TIPE1 in tubular epithelial cell aggravates diabetic nephropathy by disrupting PHB2 mediated mitophagy. Redox Biol. https:\/\/doi.org\/10.1016\/j.redox.2022.102260","journal-title":"Redox Biol"},{"issue":"4","key":"2464_CR23","doi-asserted-by":"publisher","first-page":"631","DOI":"10.3390\/cells4040631","volume":"4","author":"I Loeffler","year":"2015","unstructured":"Loeffler I, Wolf G (2015) Epithelial-to-mesenchymal transition in diabetic nephropathy: fact or fiction? Cells 4(4):631\u2013652. https:\/\/doi.org\/10.3390\/cells4040631","journal-title":"Cells"},{"issue":"5","key":"2464_CR24","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1097\/01.asn.0000065640.77499.d7","volume":"14","author":"RM Mason","year":"2003","unstructured":"Mason RM, Wahab NA (2003) Extracellular matrix metabolism in diabetic nephropathy. J Am Soc Nephrol 14(5):1358\u20131373. https:\/\/doi.org\/10.1097\/01.asn.0000065640.77499.d7","journal-title":"J Am Soc Nephrol"},{"issue":"8","key":"2464_CR25","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1159\/000524900","volume":"47","author":"L Ni","year":"2022","unstructured":"Ni L, Bai R, Zhou Q, Yuan C, Zhou LT, Wu X (2022) The correlation between ferroptosis and m6A methylation in patients with acute kidney injury. Kidney Blood Press Res 47(8):523\u2013533. https:\/\/doi.org\/10.1159\/000524900","journal-title":"Kidney Blood Press Res"},{"issue":"44","key":"2464_CR26","doi-asserted-by":"publisher","first-page":"E6806","DOI":"10.1073\/pnas.1607152113","volume":"113","author":"Y Ou","year":"2016","unstructured":"Ou Y, Wang SJ, Li D, Chu B, Gu W (2016) Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses. Proc Natl Acad Sci U S A 113(44):E6806-e6812. https:\/\/doi.org\/10.1073\/pnas.1607152113","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"11","key":"2464_CR27","doi-asserted-by":"publisher","first-page":"1390","DOI":"10.1053\/meta.2000.17721","volume":"49","author":"MJ Reed","year":"2000","unstructured":"Reed MJ, Meszaros K, Entes LJ, Claypool MD, Pinkett JG, Gadbois TM et al (2000) A new rat model of type\u00a02 diabetes: the fat-fed, streptozotocin-treated rat. Metabolism 49(11):1390\u20131394. https:\/\/doi.org\/10.1053\/meta.2000.17721","journal-title":"Metabolism"},{"issue":"Suppl 1","key":"2464_CR28","doi-asserted-by":"publisher","first-page":"S30","DOI":"10.1681\/asn.2004110970","volume":"16","author":"FP Schena","year":"2005","unstructured":"Schena FP, Gesualdo L (2005) Pathogenetic mechanisms of diabetic nephropathy. J Am Soc Nephrol 16(Suppl 1):S30-33. https:\/\/doi.org\/10.1681\/asn.2004110970","journal-title":"J Am Soc Nephrol"},{"issue":"1","key":"2464_CR29","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-22617-y","volume":"12","author":"SP Srivastava","year":"2021","unstructured":"Srivastava SP, Zhou H, Setia O, Liu B, Kanasaki K, Koya D et al (2021) Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy. Nat Commun 12(1):2368. https:\/\/doi.org\/10.1038\/s41467-021-22617-y","journal-title":"Nat Commun"},{"issue":"21","key":"2464_CR30","doi-asserted-by":"publisher","first-page":"R1292","DOI":"10.1016\/j.cub.2020.09.068","volume":"30","author":"D Tang","year":"2020","unstructured":"Tang D, Kroemer G (2020) Ferroptosis. Curr Biol 30(21):R1292-r1297. https:\/\/doi.org\/10.1016\/j.cub.2020.09.068","journal-title":"Curr Biol"},{"issue":"8","key":"2464_CR31","doi-asserted-by":"publisher","first-page":"3049","DOI":"10.1093\/ndt\/gfs260","volume":"27","author":"SC Tang","year":"2012","unstructured":"Tang SC, Lai KN (2012) The pathogenic role of the renal proximal tubular cell in diabetic nephropathy. Nephrol Dial Transplant 27(8):3049\u20133056. https:\/\/doi.org\/10.1093\/ndt\/gfs260","journal-title":"Nephrol Dial Transplant"},{"issue":"2","key":"2464_CR32","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1038\/s41422-020-00441-1","volume":"31","author":"D Tang","year":"2021","unstructured":"Tang D, Chen X, Kang R, Kroemer G (2021) Ferroptosis: molecular mechanisms and health implications. Cell Res 31(2):107\u2013125. https:\/\/doi.org\/10.1038\/s41422-020-00441-1","journal-title":"Cell Res"},{"key":"2464_CR33","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10123270","author":"C Tang","year":"2022","unstructured":"Tang C, Wang M, Liu J, Zhang C, Li L, Wu Y et al (2022) A cyclopentanone compound attenuates the over-accumulation of extracellular matrix and fibrosis in diabetic nephropathy via downregulating the TGF-\u03b2\/p38MAPK axis. Biomedicines. https:\/\/doi.org\/10.3390\/biomedicines10123270","journal-title":"Biomedicines"},{"issue":"1","key":"2464_CR34","doi-asserted-by":"publisher","DOI":"10.1080\/13510002.2025.2528334","volume":"30","author":"YC Tsai","year":"2025","unstructured":"Tsai YC, Huang JC, Yu PS, Kuo MC, Wu LY, Chang WA et al (2025) Sodium-glucose cotransporter 2 inhibitors ameliorate glutathione cysteine ligase modifier-mediated oxidative stress and subsequent ferroptosis in proximal tubules of diabetic kidney disease. Redox Rep 30(1):2528334. https:\/\/doi.org\/10.1080\/13510002.2025.2528334","journal-title":"Redox Rep"},{"key":"2464_CR35","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2022.102262","author":"Y Wang","year":"2022","unstructured":"Wang Y, Zhang M, Bi R, Su Y, Quan F, Lin Y et al (2022) ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury. Redox Biol. https:\/\/doi.org\/10.1016\/j.redox.2022.102262","journal-title":"Redox Biol"},{"issue":"10","key":"2464_CR36","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202305563","volume":"11","author":"H Wang","year":"2024","unstructured":"Wang H, Yu X, Liu D, Qiao Y, Huo J, Pan S et al (2024) VDR activation attenuates renal tubular epithelial cell ferroptosis by regulating Nrf2\/HO-1 signaling pathway in diabetic nephropathy. Adv Sci (Weinh) 11(10):e2305563. https:\/\/doi.org\/10.1002\/advs.202305563","journal-title":"Adv Sci (Weinh)"},{"issue":"3","key":"2464_CR37","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1302\/2046-3758.133.Bjr-2023-0250.R1","volume":"13","author":"J Xu","year":"2024","unstructured":"Xu J, Ruan Z, Guo Z, Hou L, Wang G, Zheng Z et al (2024) Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway. Bone Joint Res 13(3):110\u2013123. https:\/\/doi.org\/10.1302\/2046-3758.133.Bjr-2023-0250.R1","journal-title":"Bone Joint Res"},{"issue":"1","key":"2464_CR38","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1080\/13510002.2022.2134755","volume":"27","author":"H Yao","year":"2022","unstructured":"Yao H, Kong M, Du D, Ai F, Li J, Li Y (2022) Swinhoeic acid from Potentilla fragarioides ameliorates high glucose-induced oxidative stress and accumulation of ECM in mesangial cells via Keap1-dependent activation of Nrf2. Redox Rep 27(1):230\u2013238. https:\/\/doi.org\/10.1080\/13510002.2022.2134755","journal-title":"Redox Rep"},{"key":"2464_CR39","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.114925","author":"Z Ye","year":"2023","unstructured":"Ye Z, Xia Y, Li L, Li B, Chen L, Yu W et al (2023) p53 deacetylation alleviates calcium oxalate deposition-induced renal fibrosis by inhibiting ferroptosis. Biomed Pharmacother. https:\/\/doi.org\/10.1016\/j.biopha.2023.114925","journal-title":"Biomed Pharmacother"},{"key":"2464_CR40","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines12030640","author":"K Zahedi","year":"2024","unstructured":"Zahedi K, Barone S, Brooks M, Stewart TM, Foley JR, Nwafor A et al (2024) Polyamine catabolism and its role in renal injury and fibrosis in mice subjected to repeated low-dose cisplatin treatment. Biomedicines. https:\/\/doi.org\/10.3390\/biomedicines12030640","journal-title":"Biomedicines"},{"key":"2464_CR41","doi-asserted-by":"publisher","DOI":"10.1155\/2008\/704045","author":"M Zhang","year":"2008","unstructured":"Zhang M, Lv XY, Li J, Xu ZG, Chen L (2008) The characterization of high-fat diet and multiple low-dose streptozotocin induced type\u00a02 diabetes rat model. Exp Diabetes Res. https:\/\/doi.org\/10.1155\/2008\/704045","journal-title":"Exp Diabetes Res"},{"issue":"11","key":"2464_CR42","doi-asserted-by":"publisher","first-page":"3055","DOI":"10.2337\/db11-0807","volume":"60","author":"H Zheng","year":"2011","unstructured":"Zheng H, Whitman SA, Wu W, Wondrak GT, Wong PK, Fang D et al (2011) Therapeutic potential of Nrf2 activators in streptozotocin-induced diabetic nephropathy. Diabetes 60(11):3055\u20133066. https:\/\/doi.org\/10.2337\/db11-0807","journal-title":"Diabetes"}],"container-title":["Histochemistry and Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-026-02464-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00418-026-02464-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-026-02464-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T15:44:57Z","timestamp":1775403897000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00418-026-02464-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,5]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["2464"],"URL":"https:\/\/doi.org\/10.1007\/s00418-026-02464-y","relation":{},"ISSN":["1432-119X"],"issn-type":[{"value":"1432-119X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,5]]},"assertion":[{"value":"4 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"19"}}