{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T20:37:06Z","timestamp":1762375026909},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2005,10,20]],"date-time":"2005-10-20T00:00:00Z","timestamp":1129766400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Occup Environ Health"],"published-print":{"date-parts":[[2006,5]]},"DOI":"10.1007\/s00420-005-0053-8","type":"journal-article","created":{"date-parts":[[2005,10,19]],"date-time":"2005-10-19T13:20:38Z","timestamp":1129728038000},"page":"299-307","source":"Crossref","is-referenced-by-count":12,"title":["Setting occupational exposure limits in humans: contributions from the field of experimental psychology"],"prefix":"10.1007","volume":"79","author":[{"given":"Monique A.M.","family":"Smeets","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan H.A.","family":"Kroeze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela H.","family":"Dalton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2005,10,20]]},"reference":[{"key":"53_CR1","unstructured":"American Conference of Governmental and Industrial Hygienists (1998) Threshold limit values for chemical substances and physical agents"},{"key":"53_CR2","first-page":"53","volume":"80","author":"WS Cain","year":"1974","unstructured":"Cain WS (1974) Perception of odor intensity and the time-course of olfactory adaptation. ASHRAE Transactions 80:53\u201375","journal-title":"ASHRAE Transactions"},{"key":"53_CR3","unstructured":"Sherrick CE, Cholewak RW (1986) Cutaneous sensitivity. In: Boff KF, Kaufman L, Thomas JP (eds) Handbook of Perception and Human Performance. Vol. I: Sensory Processes and Perception. Wiley Interscience, New York, pp. 12-11\u201312-13"},{"key":"53_CR4","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1093\/chemse\/19.6.583","volume":"19","author":"CC Clark","year":"1994","unstructured":"Clark CC, Lawless HT (1994) Limiting response alternatives in time-intensity scaling: an examination of the halo-dumping effect. Chem Senses 19:583\u2013594","journal-title":"Chem Senses"},{"key":"53_CR5","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1093\/chemse\/8.4.315","volume":"8","author":"JE Cometto-Mu\u0148iz","year":"1984","unstructured":"Cometto-Mu\u0148iz JE, Cain WS (1984). Temporal integration of pungency. Chem Senses 8:315\u2013327","journal-title":"Chem Senses"},{"key":"53_CR6","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/0031-9384(90)90217-R","volume":"48","author":"JE Cometto-Mu\u0148iz","year":"1990","unstructured":"Cometto-Mu\u0148iz JE, Cain WS (1990). Threshold for odor and nasal pungency. Physiol Behav 48:719\u2013725","journal-title":"Physiol Behav"},{"key":"53_CR7","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/0091-3057(91)90063-8","volume":"39","author":"JE Cometto-Mu\u0148iz","year":"1991","unstructured":"Cometto-Mu\u0148iz JE, Cain WS (1991). Nasal pungency, odor, and eye irritation thresholds for homologous acetates. Pharmacol Biochem Behav 39:983\u2013989","journal-title":"Pharmacol Biochem Behav"},{"key":"53_CR8","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s004200050256","volume":"71","author":"JE Cometto-Mu\u0148iz","year":"1998","unstructured":"Cometto-Mu\u0148iz JE, Cain WS (1998) Trigeminal and olfactory sensitivity: comparison of modalities and methods of measurement. Int Arch Occup Environ Health 71:105\u2013110","journal-title":"Int Arch Occup Environ Health"},{"key":"53_CR9","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1111\/j.1749-6632.1998.tb10640.x","volume":"855","author":"JE Cometto-Mu\u0148iz","year":"1998","unstructured":"Cometto-Mu\u0148iz JE, Cain WS, Abraham MH, Kumarsingh R (1998a). Sensory properties of selected terpenes. Thresholds for odor, nasal pungency, nasal localization, and eye irritation. Ann NY Acad Sci 855:648\u2013651","journal-title":"Ann NY Acad Sci"},{"key":"53_CR10","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0091-3057(98)00054-9","volume":"60","author":"JE Cometto-Mu\u0148iz","year":"1998","unstructured":"Cometto-Mu\u0148iz JE, Cain WS, Abraham MH, Kumarsingh R (1998b).Trigeminal and olfactory chemosensory impact of selected terpenes. Pharmacol Biochem Behav 60:765\u2013770","journal-title":"Pharmacol Biochem Behav"},{"key":"53_CR11","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s004200050168","volume":"69","author":"P Dalton","year":"1997","unstructured":"Dalton P, Wysocki CJ, Brody MJ, Lawley HJ (1997) The influence of cognitive bias on the perceived odor, irritation and health symptoms from chemical exposure. Int Arch Occup Environ Health 69:407\u2013417","journal-title":"Int Arch Occup Environ Health"},{"key":"53_CR12","first-page":"340","volume":"61","author":"PH Dalton","year":"2000","unstructured":"Dalton PH, Dilks DD, Banton MI (2000) Evaluation of odor and sensory irritation thresholds for methyl isobutyl ketone in humans. Am Ind Hyg Assoc J 61:340\u2013350","journal-title":"Am Ind Hyg Assoc J"},{"key":"53_CR13","volume-title":"Psychology of Perception,","author":"WN Dember","year":"1979","unstructured":"Dember WN, Warm JS (1979) Psychology of Perception, 2 ed. Holt, Rinehart and Winston, New York","edition":"2"},{"key":"53_CR14","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1002\/(SICI)1097-0274(199805)33:5<439::AID-AJIM3>3.0.CO;2-N","volume":"33","author":"RB Dick","year":"1998","unstructured":"Dick RB, Ahlers H (1998) Chemicals in the workplace: incorporating human neurobehavioral testing into the regulatory process. Am J Ind Med 33:439\u2013453","journal-title":"Am J Ind Med"},{"key":"53_CR15","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0031-9384(78)90070-7","volume":"20","author":"RL Doy","year":"1978","unstructured":"Doy RL, Brugger WE, Jurs PC, Orndorff MA, Snyder PJ, Dale Lowry L (1978) Intranasal trigeminal stimulation from odorous volatiles: Psychometric responses from anosmic and normal humans. Physiol & Behav 20:175\u2013185","journal-title":"Physiol & Behav"},{"key":"53_CR16","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1080\/10408440490269586","volume":"34","author":"RL Doty","year":"2004","unstructured":"Doty RL, Cometto-Mu\u0148iz JE, Jalowayski AA, Dalton P, Kendal-Reed M, Hodgson M (2004) Assessment of upper respiratory tract and ocular irritative effects of volatile chemicals in humans. Crit Rev Toxicol 34:85\u2013142","journal-title":"Crit Rev Toxicol"},{"key":"53_CR17","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1093\/chemse\/20.6.645","volume":"20","author":"RL Doty","year":"1995","unstructured":"Doty RL, McKeown DA, Lee WW, Shaman P (1995). A study of the test-retest reliability of ten olfactory tests. Chem Senses 20:645\u2013656","journal-title":"Chem Senses"},{"key":"53_CR18","volume-title":"Woodworth\u2019s & Schlosberg\u2019s Experimental Psychology","author":"T Engen","year":"1971","unstructured":"Engen T (1971) Psychophysics I Discrimination and detection. In: Kling J, Riggs L (eds) Woodworth\u2019s & Schlosberg\u2019s Experimental Psychology, Holt, Rinehart & Winston, New York"},{"key":"53_CR19","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/978-94-015-9101-0_5","volume-title":"The politics of chemical risk: Scenarios for a regulatory future","author":"VJ Feron","year":"1998","unstructured":"Feron VJ (1998) Recommending health-based exposure limits in the national and international arena: a personal view. In: Bal R, Halffman W (eds) The politics of chemical risk: Scenarios for a regulatory future. Kluwer Academic Publishers, Dordrecht, pp 121\u2013129"},{"key":"53_CR20","first-page":"575","volume":"Pharmacol","author":"J Frasnelli","year":"2005","unstructured":"Frasnelli J, Hummel T (2005) Intranasal trigeminal threshold in healthy subjects. Environ Toxicol Pharmacol:575\u2013580","journal-title":"Environ Toxicol"},{"key":"53_CR21","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1365-2621.1982.tb11045.x","volume":"47","author":"JER Frijters","year":"1981","unstructured":"Frijters JER (1981) Expanded tables for conversion of a proportion of correct responses (Pc) to the measure of sensory difference (d\u2019) for the triangular method and the 3-alternative forced choice procedure. J Food Sci 47:139\u2013143","journal-title":"J Food Sci"},{"key":"53_CR22","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3758\/BF03205007","volume":"48","author":"BG Green","year":"1990","unstructured":"Green BG (1990) Spatial summation of chemical irritation and itch produced by topical application of capsaicin. Percept Psychophys 48:12\u201318","journal-title":"Percept Psychophys"},{"key":"53_CR23","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1080\/00039899909602241","volume":"Health54","author":"A Hempel-J\u00f8rgensen","year":"1999","unstructured":"Hempel-J\u00f8rgensen A, Kjaergaard SK, M\u00f8lhave L, Hudnell HK (1999) Time course of sensory eye irritation in humans exposed to N-butanol and 1-Octene. Arch Environ Health54:86\u201394","journal-title":"Arch Environ"},{"issue":"1","key":"53_CR24","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1093\/chemse\/21.1.75","volume":"21","author":"T Hummel","year":"1996","unstructured":"Hummel T, Barz S, Lotsch J, Roscher S, Kettenmann B, Kobal G (1996) Loss of olfactory function leads to a decrease of trigeminal sensitivity. Chem Senses 21(1):75\u201380","journal-title":"Chem Senses"},{"key":"53_CR25","unstructured":"Johanson G (2001) Basic concepts in toxicological risk assessment. Paper presented at the Occupational exposure limits - approaches and criteria, In: Proceedings from a NIVA course, Uppsala, Sweden"},{"key":"53_CR26","doi-asserted-by":"crossref","first-page":"796","DOI":"10.3758\/BF03205405","volume":"10","author":"H Kaplan","year":"1978","unstructured":"Kaplan H, MacMillan N, Creelman C (1978) Tables of d\u2019 for variable-standard discrimination paradigms. Behav Res Meth Instr 10:796\u2013813","journal-title":"Behav Res Meth Instr"},{"key":"53_CR27","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1093\/chemse\/23.1.71","volume":"23","author":"M Kendal-Reed","year":"1998","unstructured":"Kendal-Reed M, Walker J, Morgan WT, LaMacchio M, Lutz RW (1998) Human responses to proprionic acid. I . Quantification of within- and between-participant variation in perception by normosmics and anosmics. Chem Senses 23:71\u201382","journal-title":"Chem Senses"},{"key":"53_CR28","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.etap.2004.12.056","volume":"19","author":"E Kieswetter","year":"2005","unstructured":"Kieswetter E, Von Thriel C, Sch\u00e4per M, Blaskwewicz M, Seeber A (2005) Eye blinks as indicator for sensory irritation during constant and peak exposures to 2-ethylhexanol. Environ Tox Pharm 19:531\u2013541","journal-title":"Environ Tox Pharm"},{"key":"53_CR29","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.3758\/BF03194552","volume":"63","author":"SA Klein","year":"2001","unstructured":"Klein SA (2001) Measuring, estimating, and understanding the psychometric function: A commentary. Percept & Psychophys 63:1421\u20131455","journal-title":"Percept & Psychophys"},{"key":"53_CR30","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s00420-003-0502-1","volume":"77","author":"J Klen\u00f8","year":"2004","unstructured":"Klen\u00f8 J, Wolkoff P (2004) Changes in eye blink frequency as a measure of trigeminal stimulation by exposure to limonene oxidation products, isoprene oxidation products and nitrate radicals. Int Arch Occup Environ Health 77:235\u2013243","journal-title":"Int Arch Occup Environ Health"},{"key":"53_CR31","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1111\/j.1559-1816.1990.tb01476.x","volume":"20","author":"SC Knasko","year":"1990","unstructured":"Knasko SC, Gilbert AN (1990) Emotional state, physical well-being, and performance in the presence of feigned ambient odor. J Appl Social Psychol 20:1345\u20131357","journal-title":"J Appl Social Psychol"},{"key":"53_CR32","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/BF01954845","volume":"45","author":"G Kobal","year":"1989","unstructured":"Kobal G, Van Toller S, Hummel T (1989) Is there directional smelling? Experientia 45:130\u2013132","journal-title":"Experientia"},{"key":"53_CR33","volume-title":"Sensoryrocesses: The newsychophysics","author":"LE Marks","year":"1974","unstructured":"Marks LE (1974) Sensory processes: The new psychophysics. Academic Press, New York"},{"key":"53_CR34","first-page":"13","volume-title":"Artifact in Behavioral Research","author":"WJ McGuire","year":"1969","unstructured":"McGuire WJ (1969) Suspiciousness of experimenter\u2019s intent. In: Rosenthal R, Rosnow RL (eds) Artifact in Behavioral Research, Academic Press, New York, pp 13\u201357"},{"key":"53_CR35","volume-title":"Sensory Evaluation Techniques","author":"M Meilgaard","year":"1987","unstructured":"Meilgaard M, Civille GV, Carr BT (1987) Sensory Evaluation Techniques. CRC Press, Boca Raton"},{"key":"53_CR36","unstructured":"Opiekun RE, McDermott R, Dalton PH (2003) Gender differences and nasal integration studies using an ocular exposure device for detection or irritation thresholds: The T.I.D.E. System. Poster presented at Achems Conference, Sarasota, Fl"},{"key":"53_CR37","first-page":"143","volume-title":"Artifact in Behavioral Research","author":"MT Orne","year":"1969","unstructured":"Orne MT (1969) Demand Characteristics and the Concept of Quasi-Controls. In: Rosenthal R, Rosnow RL (eds) Artifact in Behavioral Research. Academic Press, New York, pp 143\u2013179"},{"key":"53_CR38","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1202\/0002-8894(2001)062<0697:AACFSO>2.0.CO;2","volume":"62","author":"D Paustenbach","year":"2001","unstructured":"Paustenbach D (2001) Approaches and considerations for setting occupational exposure limits for sensory irritants: report of recent symposia. Am Ind Hyg Assoc J 62:697\u2013704","journal-title":"Am Ind Hyg Assoc J"},{"key":"53_CR39","volume-title":"Bias in quantifying judgments","author":"EC Poulton","year":"1989","unstructured":"Poulton EC (1989) Bias in quantifying judgments. Lawrence Erlbaum, Hove, UK"},{"key":"53_CR40","doi-asserted-by":"crossref","unstructured":"Porter J, Anand T, Johnson B, Khan RM, Sobel N (2005) Brain mechanisms for extracting spatial information from smell. Neuron:581\u2013592","DOI":"10.1016\/j.neuron.2005.06.028"},{"key":"53_CR41","unstructured":"Sherrick CE, Cholewak RW (1986) Cuteanous sensitivity. In: KR Boff, L Kaufman, and Thomans, JP (eds) Handbook of perception and human performance. Vol I: Sensory processes and perception. New York: Wiley Interscience, pp 12\u201311 \u2013 12\u201313"},{"key":"53_CR42","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1093\/chemse\/26.3.339","volume":"26","author":"D Shusterman","year":"2001","unstructured":"Shusterman D (2001) Odor-associated health complaints: competing explanatory models. Chem Senses 26:339\u2013343","journal-title":"Chem Senses"},{"key":"53_CR43","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s00420-003-0459-0","volume":"76","author":"D Shusterman","year":"2003","unstructured":"Shusterman D, Murphy MA, Balmes J (2003) Differences in nasal irritant sensitivity by age, gender, and allergic rhinitis status. Int Arch Occup Environ Health 76:577\u2013583","journal-title":"Int Arch Occup Environ Health"},{"key":"53_CR44","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s00420-002-0364-y","volume":"75","author":"M Smeets","year":"2002","unstructured":"Smeets M, Dalton P (2002) Perceived odor and irritation of isopropanol: a comparison between naive controls and occupationally exposed workers. Int Arch Occup Environ Health 75:541\u2013548","journal-title":"Int Arch Occup Environ Health"},{"key":"53_CR45","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s00420-002-0311-y","volume":"75","author":"G Triebig","year":"2002","unstructured":"Triebig G (2002) Chemosensory irritation and the setting of occupational exposure limits. Int Arch Occup Environ Health 75:281\u2013282","journal-title":"Int Arch Occup Environ Health"},{"key":"53_CR46","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.1016\/j.visres.2003.08.002","volume":"43","author":"A Vassilev","year":"2003","unstructured":"Vassilev A, Mihaylova MS, Racheva K, Zlatkova M, Anderson RS (2003) Spatial summation of S-cone ON and OFF signals: effects of retinal eccentricity. Vision Res 43:2875\u20132884","journal-title":"Vision Res"},{"key":"53_CR47","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.etap.2004.12.024","volume":"19","author":"C Thriel Van","year":"2005","unstructured":"Van Thriel C, Kieswetter E, Sch\u00e4per M, Blaskewicz M, Golka K, Seeber A (2005) An integrative approach considering acute symptoms and intensity ratings of chemosensory sensations during experimental exposures. Environ Tox Pharm 19:589\u2013598","journal-title":"Environ Tox Pharm"},{"key":"53_CR48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.2044-8317.1965.tb00689.x","volume":"18","author":"GB Wetherill","year":"1965","unstructured":"Wetherill GB, Levitt H (1965) Sequential estimation of points on a psychometric function. Br J Math Stat Psychol 18:1\u201310","journal-title":"Br J Math Stat Psychol"},{"key":"53_CR49","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1093\/chemse\/bjh018","volume":"29","author":"PM Wise","year":"2004","unstructured":"Wise PM, Radil T, Wysocki CJ (2004) Temporal integration in nasal lateralization and nasal detection of carbon dioxide. Chem Senses 29:137\u2013142","journal-title":"Chem Senses"},{"key":"53_CR50","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/toxsci\/kfi229","volume":"87","author":"PM Wise","year":"2005","unstructured":"Wise PM, Canty TM, Wysocki CJ (2005) Temporal integration of nasal irritation from ammonia at threshold and supra-threshold levels. Toxicol Sci 87:223\u201331","journal-title":"Toxicol Sci"},{"key":"53_CR51","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1080\/15428119791012342","volume":"58","author":"CJ Wysocki","year":"1997","unstructured":"Wysocki CJ, Dalton P, Brody MJ, Lawley HJ (1997) Acetone odor and irritation thresholds obtained from acetone-exposed factory workers and from control (occupationally unexposed) subjects. Am Ind Hyg Assoc J 58:704\u2013712","journal-title":"Am Ind Hyg Assoc J"},{"key":"53_CR52","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3758\/BF03194788","volume":"65","author":"CJ Wysocki","year":"2003","unstructured":"Wysocki CJ, Cowart BJ & Radil T (2003) Nasal trigeminal chemosensitivity across the adult lifespan. Percept & Psychophys 65:115\u2013122","journal-title":"Percept & Psychophys"}],"container-title":["International Archives of Occupational and Environmental Health"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00420-005-0053-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00420-005-0053-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00420-005-0053-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T20:11:29Z","timestamp":1559074289000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00420-005-0053-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10,20]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["53"],"URL":"https:\/\/doi.org\/10.1007\/s00420-005-0053-8","relation":{},"ISSN":["0340-0131","1432-1246"],"issn-type":[{"value":"0340-0131","type":"print"},{"value":"1432-1246","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,10,20]]}}}