{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T01:07:10Z","timestamp":1715562430327},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2005,2,18]],"date-time":"2005-02-18T00:00:00Z","timestamp":1108684800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Occup Environ Health"],"published-print":{"date-parts":[[2005,4]]},"DOI":"10.1007\/s00420-005-0605-y","type":"journal-article","created":{"date-parts":[[2005,2,17]],"date-time":"2005-02-17T19:13:55Z","timestamp":1108667635000},"page":"171-177","source":"Crossref","is-referenced-by-count":15,"title":["Functional adrenergic receptor polymorphisms and idiopathic orthostatic intolerance"],"prefix":"10.1007","volume":"78","author":[{"given":"R.","family":"Winker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Barth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Valic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Maier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Osterode","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Pilger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. W.","family":"R\ufffddiger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2005,2,18]]},"reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"2877","DOI":"10.1161\/01.CIR.101.25.2877","volume":"101","author":"MS Bray","year":"2000","unstructured":"Bray MS, Krushkal J, Li L, Ferrell R, Kardia S, Sing CF, Turner ST, Boerwinkle E (2000) Positional genomic analysis identifies the beta(2)-adrenergic receptor gene as a susceptibility locus for human hypertension. Circulation 101:2877?2882","journal-title":"Circulation"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1161\/01.CIR.103.8.1048","volume":"103","author":"OE Brodde","year":"2001","unstructured":"Brodde O E, Buscher R, Tellkamp R, Radke J, Dhein S, Insel P A (2001) Blunted cardiac responses to receptor activation in subjects with Thr164Ile beta(2)-adrenoceptors. Circulation 103:1048?1050","journal-title":"Circulation"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1056\/NEJMoa010819","volume":"345","author":"V Dishy","year":"2001","unstructured":"Dishy V, Sofowora GG, Xie HG, Kim RB, Byrne DW, Stein CM, Wood AJ (2001) The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization. N Engl J Med 345:1030?1035","journal-title":"N Engl J Med"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"10483","DOI":"10.1073\/pnas.97.19.10483","volume":"97","author":"CM Drysdale","year":"2000","unstructured":"Drysdale CM, McGraw DW, Stack CB, Stephens JC, Judson RS, Nandabalan K, Arnold K, Ruano G, Liggett SB (2000) Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness. Proc Natl Acad Sci U S A 97:10483?10488","journal-title":"Proc Natl Acad Sci U S A"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"3086","DOI":"10.1161\/01.CIR.102.25.3086","volume":"102","author":"WB Farquhar","year":"2000","unstructured":"Farquhar W B, Taylor J A, Darling S E, Chase K P, Freeman R (2000) Abnormal baroreflex responses in patients with idiopathic orthostatic intolerance. Circulation 102:3086?3091","journal-title":"Circulation"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0010-4825(98)00005-5","volume":"28","author":"G Gratze","year":"1998","unstructured":"Gratze G, Fortin J, Holler A, Grasenick K, Pfurtscheller G, Wach P, Schonegger J, Kotanko P, Skrabal F (1998) A software package for non-invasive, real-time beat-to-beat monitoring of stroke volume, blood pressure, total peripheral resistance and for assessment of autonomic function. Comput Biol Med 28:121?142","journal-title":"Comput Biol Med"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"23116","DOI":"10.1016\/S0021-9258(19)49434-9","volume":"268","author":"SA Green","year":"1993","unstructured":"Green SA, Cole G, Jacinto M, Innis M, Liggett SB (1993) A polymorphism of the human beta 2-adrenergic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor. J Biol Chem 268:23116?23121","journal-title":"J Biol Chem"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"9414","DOI":"10.1021\/bi00198a006","volume":"33","author":"SA Green","year":"1994","unstructured":"Green SA, Turki J, Innis M, Liggett SB (1994) Amino-terminal polymorphisms of the human beta 2-adrenergic receptor impart distinct agonist-promoted regulatory properties. Biochemistry 33:9414?9419","journal-title":"Biochemistry"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1046\/j.1460-9592.2003.t01-1-00155.x","volume":"26","author":"BP Grubb","year":"2003","unstructured":"Grubb BP, Kosinski DJ, Kanjwal Y (2003) Orthostatic hypotension: causes, classification, and treatment. Pacing Clin Electrophysiol 26:892?901","journal-title":"Pacing Clin Electrophysiol"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1042\/cs1030517","volume":"103","author":"P Heinonen","year":"2002","unstructured":"Heinonen P, Jartti L, Jarvisalo MJ, Pesonen U, Kaprio JA, Ronnemaa T, Raitakari OT, Scheinin M (2002) Deletion polymorphism in the alpha2B-adrenergic receptor gene is associated with flow-mediated dilatation of the brachial artery. Clin Sci Lond 103:517?524","journal-title":"Clin Sci Lond"},{"key":"CR11","first-page":"537","volume":"139","author":"BD Hoit","year":"2000","unstructured":"Hoit BD, Suresh DP, Craft L, Walsh RA, Liggett SB (2000) Beta2-adrenergic receptor polymorphisms at amino acid 16 differentially influence agonist-stimulated blood pressure and peripheral blood flow in normal individuals. Am Heart J 139:537?542","journal-title":"Am Heart J"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/S0002-9629(15)40482-3","volume":"317","author":"G Jacob","year":"1999","unstructured":"Jacob G, Biaggioni I (1999) Idiopathic orthostatic intolerance and postural tachycardia syndromes. Am J Med Sci 317:88?101","journal-title":"Am J Med Sci"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/sj.bjp.0701658","volume":"123","author":"B January","year":"1998","unstructured":"January B, Seibold A, Allal C, Whaley BS, Knoll BJ, Moore RH, Dickey BF, Barber R, Clark RB (1998) Salmeterol-induced desensitization, internalization and phosphorylation of the human beta2-adrenoceptor. Br J Pharmacol 123:701?711","journal-title":"Br J Pharmacol"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S0009-9236(03)00068-7","volume":"74","author":"JA Johnson","year":"2003","unstructured":"Johnson JA, Zineh I, Puckett BJ, McGorray SP, Yarandi HN, Pauly DF (2003) Beta 1-adrenergic receptor polymorphisms and antihypertensive response to metoprolol. Clin Pharmacol Ther 74:44?52","journal-title":"Clin Pharmacol Ther"},{"key":"CR15","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/S0002-9629(15)40642-1","volume":"318","author":"J Jordan","year":"1999","unstructured":"Jordan J, Shannon JR, Jacob G, Pohar B, Robertson D (1999) Interaction of genetic predisposition and environmental factors in the pathogenesis of idiopathic orthostatic intolerance. Am J Med Sci 318:298?303","journal-title":"Am J Med Sci"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1161\/hy1201.097202","volume":"39","author":"J Jordan","year":"2002","unstructured":"Jordan J, Shannon JR, Diedrich A, Black BK, Robertson D (2002) Increased sympathetic activation in idiopathic orthostatic intolerance: role of systemic adrenoreceptor sensitivity. Hypertension 39:173?178","journal-title":"Hypertension"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1172\/JCI4059","volume":"102","author":"SB Liggett","year":"1998","unstructured":"Liggett S B, Wagoner LE, Craft LL, Hornung RW, Hoit BD, McIntosh TC, Walsh RA (1998) The Ile164 beta2-adrenergic receptor polymorphism adversely affects the outcome of congestive heart failure. J Clin Invest 102:1534?1539","journal-title":"J Clin Invest"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"12670","DOI":"10.1074\/jbc.274.18.12670","volume":"274","author":"DA Mason","year":"1999","unstructured":"Mason DA, Moore JD, Green SA, Liggett SB (1999) A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor. J Biol Chem 274:12670?12674","journal-title":"J Biol Chem"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1038\/nm930","volume":"9","author":"J Mialet Perez","year":"2003","unstructured":"Mialet Perez J, Rathz DA, Petrashevskaya NN, Hahn HS, Wagoner LE, Schwartz A, Dorn GW, Liggett SB (2003) Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure. Nat Med 9:1300?1305","journal-title":"Nat Med"},{"key":"CR20","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1086\/339621","volume":"70","author":"K Ranade","year":"2002","unstructured":"Ranade K, Jorgenson E, Sheu WH, Pei D, Hsiung CA, Chiang FT, Chen YD, Pratt R, Olshen RA, Curb D, Cox DR, Botstein D, Risch N (2002) A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate. Am J Hum Genet 70:935?942","journal-title":"Am J Hum Genet"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1097\/00005344-200202000-00001","volume":"39","author":"DA Rathz","year":"2002","unstructured":"Rathz DA, Brown KM, Kramer LA, Liggett SB (2002) Amino acid 49 polymorphisms of the human beta1-adrenergic receptor affect agonist-promoted trafficking. J Cardiovasc Pharmacol 39:155?160","journal-title":"J Cardiovasc Pharmacol"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1056\/NEJM200002243420803","volume":"342","author":"JR Shannon","year":"2000","unstructured":"Shannon JR, Flattem NL, Jordan J, Jacob G, Black BK, Biaggioni I, Blakely RD, Robertson D (2000) Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency. N Engl J Med 342:541?549","journal-title":"N Engl J Med"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1111\/j.1476-5381.1996.tb15552.x","volume":"118","author":"K Shibata","year":"1996","unstructured":"Shibata K, Hirasawa A, Moriyama N, Kawabe K, Ogawa S, Tsujimoto G (1996) Alpha 1a-adrenoceptor polymorphism: pharmacological characterization and association with benign prostatic hypertrophy. Br J Pharmacol 118:1403?1408","journal-title":"Br J Pharmacol"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0165-6147(00)01758-2","volume":"22","author":"KM Small","year":"2001","unstructured":"Small KM, Liggett SB (2001) Identification and functional characterization of alpha(2)-adrenoceptor polymorphisms. Trends Pharmacol Sci 22:471?477","journal-title":"Trends Pharmacol Sci"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"38518","DOI":"10.1074\/jbc.M004550200","volume":"275","author":"KM Small","year":"2000","unstructured":"Small KM, Forbes SL, Brown KM, Liggett SB (2000a) An asn to lys polymorphism in the third intracellular loop of the human alpha 2A-adrenergic receptor imparts enhanced agonist-promoted Gi coupling. J Biol Chem 275:38518?38523","journal-title":"J Biol Chem"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"23059","DOI":"10.1074\/jbc.M000796200","volume":"275","author":"KM Small","year":"2000","unstructured":"Small KM, Forbes SL, Rahman FF, Bridges KM, Liggett SB (2000b) A four amino acid deletion polymorphism in the third intracellular loop of the human alpha 2C-adrenergic receptor confers impaired coupling to multiple effectors. J Biol Chem 275:23059?23064","journal-title":"J Biol Chem"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"4917","DOI":"10.1074\/jbc.M008118200","volume":"276","author":"KM Small","year":"2001","unstructured":"Small KM, Brown KM, Forbes SL, Liggett SB (2001) Polymorphic deletion of three intracellular acidic residues of the alpha 2B-adrenergic receptor decreases G protein-coupled receptor kinase-mediated phosphorylation and desensitization. J Biol Chem 276:4917?4922","journal-title":"J Biol Chem"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S0076-6879(02)43152-7","volume":"343","author":"KM Small","year":"2002","unstructured":"Small KM, Rathz DA, Liggett SB (2002a) Identification of adrenergic receptor polymorphisms. Methods Enzymol 343:459?475","journal-title":"Methods Enzymol"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1056\/NEJMoa020803","volume":"347","author":"KM Small","year":"2002","unstructured":"Small KM, Wagoner LE, Levin AM, Kardia SL, Liggett SB (2002b) Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure. N Engl J Med 347:1135?1142","journal-title":"N Engl J Med"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1146\/annurev.pharmtox.43.100901.135823","volume":"43","author":"KM Small","year":"2003","unstructured":"Small KM, McGraw DW, Liggett SB (2003) Pharmacology and physiology of human adrenergic receptor polymorphisms. Annu Rev Pharmacol Toxicol 43:381?411","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1378\/chest.109.6.1636","volume":"109","author":"EM Tschernko","year":"1996","unstructured":"Tschernko EM, Hofer S, Bieglmayer C, Wisser W, Haider W (1996) Early postoperative stress: video-assisted wedge resection\/lobectomy vs conventional axillary thoracotomy. Chest 109:1636?1642","journal-title":"Chest"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"10483","DOI":"10.1073\/pnas.93.19.10483","volume":"93","author":"J Turki","year":"1996","unstructured":"Turki J, Lorenz JN, Green SA, Donnelly ET, Jacinto M, Liggett SB (1996) Myocardial signaling defects and impaired cardiac function of a human beta 2-adrenergic receptor polymorphism expressed in transgenic mice. Proc Natl Acad Sci U S A 93:10483?10488","journal-title":"Proc Natl Acad Sci U S A"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1161\/01.RES.86.8.834","volume":"86","author":"LE Wagoner","year":"2000","unstructured":"Wagoner LE, Craft LL, Singh B, Suresh DP, Zengel PW, McGuire N, Abraham WT, Chenier TC, Dorn GW II, Liggett SB (2000) Polymorphisms of the beta(2)-adrenergic receptor determine exercise capacity in patients with heart failure. Circ Res 86:834?840","journal-title":"Circ Res"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1067\/mhj.2002.125325","volume":"144","author":"LE Wagoner","year":"2002","unstructured":"Wagoner LE, Craft LL, Zengel P, McGuire N, Rathz DA, Dorn GW II, Liggett SB (2002) Polymorphisms of the beta1-adrenergic receptor predict exercise capacity in heart failure. Am Heart J 144:840?846","journal-title":"Am Heart J"},{"key":"CR35","first-page":"325","volume":"36","author":"R Winker","year":"2001","unstructured":"Winker R, R\u00fcdiger H (2001) Orthostatische Intoleranz - Bedeutung in der Arbeitsmedizin. ASU 36:325?331","journal-title":"ASU"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s00420-002-0395-4","volume":"76","author":"R Winker","year":"2003","unstructured":"Winker R, Barth A, Dorner W, Mayr O, Pilger A, Ivancsits S, Ponocny I, Heider A, Wolf C, Rudiger HW (2003) Diagnostic management of orthostatic intolerance in the workplace. Int Arch Occup Environ Health 76:143?150","journal-title":"Int Arch Occup Environ Health"}],"container-title":["International Archives of Occupational and Environmental Health"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00420-005-0605-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00420-005-0605-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00420-005-0605-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T05:01:48Z","timestamp":1625461308000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00420-005-0605-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,18]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["605"],"URL":"https:\/\/doi.org\/10.1007\/s00420-005-0605-y","relation":{},"ISSN":["0340-0131","1432-1246"],"issn-type":[{"value":"0340-0131","type":"print"},{"value":"1432-1246","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2,18]]}}}