{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T09:22:18Z","timestamp":1758705738603},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T00:00:00Z","timestamp":1547769600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"German Ministry of Education and Research","award":["01 EE 9411-3"],"award-info":[{"award-number":["01 EE 9411-3"]}]},{"name":"German Ministry for Economy and Labour"},{"name":"German Federal Institute for Occupational Safety and Health"},{"name":"German Ministry of Labour and Social Affairs"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Arch Occup Environ Health"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1007\/s00420-019-01402-x","type":"journal-article","created":{"date-parts":[[2019,1,17]],"date-time":"2019-01-17T22:43:54Z","timestamp":1547765034000},"page":"673-681","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Work-related stress and incident asthma and rhinitis: results from the SOLAR study"],"prefix":"10.1007","volume":"92","author":[{"given":"Felix","family":"Forster","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Weinmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Gerlich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolff","family":"Schlotz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gudrun","family":"Weinmayr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jon","family":"Genuneit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doris","family":"Windstetter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Vogelberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"von Mutius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis","family":"Nowak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katja","family":"Radon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,1,18]]},"reference":[{"issue":"1","key":"1402_CR1","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.iac.2004.09.001","volume":"25","author":"GR Bloomberg","year":"2005","unstructured":"Bloomberg GR, Chen E (2005) The relationship of psychologic stress with childhood asthma. Immunol Allergy Clin N Am 25(1):83\u2013105","journal-title":"Immunol Allergy Clin N Am"},{"issue":"9","key":"1402_CR2","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1164\/rccm.201307-1349OC","volume":"189","author":"WM Brunner","year":"2014","unstructured":"Brunner WM, Schreiner PJ, Sood A, Jacobs DR, JR (2014) Depression and risk of incident asthma in adults. The CARDIA study. Am J Respir Crit Care Med 189(9):1044\u20131051","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"1402_CR3","doi-asserted-by":"publisher","first-page":"1360","DOI":"10.1016\/j.jaci.2007.09.019","volume":"120","author":"L Cazzoletti","year":"2007","unstructured":"Cazzoletti L, Marcon A, Janson C, Corsico A, Jarvis D, Pin I, Accordini S, Almar E, Bugiani M, Carolei A, Cerveri I, Duran-Tauleria E, Gislason D, Gulsvik A, Jogi R, Marinoni A, Martinez-Moratalla J, Vermeire P, Marco R de (2007) Asthma control in Europe: a real-world evaluation based on an international population-based study. J Allergy Clin Immunol 120(6):1360\u20131367","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"1402_CR4","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.iac.2010.09.009","volume":"31","author":"ND Dave","year":"2011","unstructured":"Dave ND, Xiang L, Rehm KE, Marshall GD, JR (2011) Stress and allergic diseases. Immunol Allergy Clin N Am 31(1):55\u201368","journal-title":"Immunol Allergy Clin N Am"},{"issue":"127","key":"1402_CR5","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1183\/09059180.00007112","volume":"22","author":"SB Nijs de","year":"2013","unstructured":"de Nijs SB, Venekamp LN, Bel EH (2013) Adult-onset asthma: is it really different? Eur Respir Rev Off J Eur Respir Soc 22(127):44\u201352","journal-title":"Eur Respir Rev Off J Eur Respir Soc"},{"issue":"8","key":"1402_CR6","doi-asserted-by":"publisher","first-page":"783","DOI":"10.3109\/02770903.2011.608459","volume":"48","author":"A Eng","year":"2011","unstructured":"Eng A, Mannetje A, Pearce N, Douwes J (2011) Work-related stress and asthma: results from a workforce survey in New Zealand. J Asthma Off J Assoc Care Asthma 48(8):783\u2013789","journal-title":"J Asthma Off J Assoc Care Asthma"},{"key":"1402_CR7","volume-title":"Sixth European working conditions survey\u2014overview report","author":"Eurofound","year":"2016","unstructured":"Eurofound (2016) Sixth European working conditions survey\u2014overview report. Publications Office of the European Union, Luxembourg"},{"issue":"4","key":"1402_CR8","doi-asserted-by":"publisher","first-page":"256","DOI":"10.2500\/aap.2015.36.3847","volume":"36","author":"M Frieri","year":"2015","unstructured":"Frieri M, O\u2019Connor M, Nassef M (2015) Asthma, stress, and depression in women. Allergy Asthma Proc 36(4):256\u2013261","journal-title":"Allergy Asthma Proc"},{"key":"1402_CR9","unstructured":"Health and Safety Executive (2016) Work related stress, anxiety and depression statistics in Great Britain 2016. \n                    http:\/\/www.hse.gov.uk\/statistics\/\n                    \n                  . Accessed 19 Oct 2017"},{"issue":"6","key":"1402_CR10","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1111\/all.12381","volume":"69","author":"K Heikkil\u00e4","year":"2014","unstructured":"Heikkil\u00e4 K, Madsen IEH, Nyberg ST, Fransson EI, Westerlund H, Westerholm PJM, Virtanen M, Vahtera J, Vaananen A, Theorell T, Suominen SB, Shipley MJ, Salo P, Rugulies R, Pentti J, Pejtersen JH, Oksanen T, Nordin M, Nielsen ML, Kouvonen A, Koskinen A, Koskenvuo M, Knutsson A, Ferrie JE, Dragano N, Burr H, Borritz M, Bjorner JB, Alfredsson L, Batty GD, Singh-Manoux A, Kivimaki M (2014) Job strain and the risk of severe asthma exacerbations: a meta-analysis of individual-participant data from 100 000 European men and women. Allergy 69(6):775\u2013783","journal-title":"Allergy"},{"key":"1402_CR11","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1186\/1471-2458-11-298","volume":"11","author":"S Heinrich","year":"2011","unstructured":"Heinrich S, Peters A, Kellberger J, Ellenberg D, Genuneit J, Nowak D, Vogelberg C, Mutius E von, Weinmayr G, Radon K (2011) Study on occupational allergy risks (SOLAR II) in Germany: design and methods. BMC Public Health 11:298","journal-title":"BMC Public Health"},{"issue":"1","key":"1402_CR12","first-page":"1","volume":"45","author":"J Honaker","year":"2011","unstructured":"Honaker J, King G, Blackwell M (2011) Amelia II: a program for missing data. J Stat Softw 45(1):1\u201347","journal-title":"J Stat Softw"},{"issue":"8","key":"1402_CR13","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1093\/occmed\/kqq138","volume":"60","author":"J Houdmont","year":"2010","unstructured":"Houdmont J, Cox T, Griffiths A (2010) Work-related stress case definitions and prevalence rates in national surveys. Occup Med (Oxf Engl) 60(8):658\u2013661","journal-title":"Occup Med (Oxf Engl)"},{"issue":"12","key":"1402_CR14","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1176\/ajp.144.12.1561","volume":"144","author":"K Hsu","year":"1987","unstructured":"Hsu K, Marshall V (1987) Prevalence of depression and distress in a large sample of Canadian residents, interns, and fellows. Am J Psychiatry 144(12):1561\u20131566","journal-title":"Am J Psychiatry"},{"issue":"10","key":"1402_CR15","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1034\/j.1398-9995.2001.00112.x","volume":"56","author":"E Huovinen","year":"2001","unstructured":"Huovinen E, Kaprio J, Koskenvuo M (2001) Asthma in relation to personality traits, life satisfaction, and stress: a prospective study among 11,000 adults. Allergy 56(10):971\u2013977","journal-title":"Allergy"},{"issue":"9","key":"1402_CR16","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1136\/oem.57.9.635","volume":"57","author":"SM Kennedy","year":"2000","unstructured":"Kennedy SM, Le Moual N, Choudat D, Kauffmann F (2000) Development of an asthma specific job exposure matrix and its application in the epidemiological study of genetics and environment in asthma (EGEA). Occup Environ Med 57(9):635\u2013641","journal-title":"Occup Environ Med"},{"issue":"5","key":"1402_CR17","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1016\/j.psyneuen.2008.11.010","volume":"34","author":"JK Kiecolt-Glaser","year":"2009","unstructured":"Kiecolt-Glaser JK, Heffner KL, Glaser R, Malarkey WB, Porter K, Atkinson C, Laskowski B, Lemeshow S, Marshall GD (2009) How stress and anxiety can alter immediate and late phase skin test responses in allergic rhinitis. Psychoneuroendocrinology 34(5):670\u2013680","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"1402_CR18","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1017\/S0003055401000235","volume":"95","author":"G King","year":"2001","unstructured":"King G, Honaker J, Joseph A, Scheve K (2001) Analyzing incomplete political science data: an alternative algorithm for multiple imputation. Am Polit Sci Rev 95(1):49\u201369","journal-title":"Am Polit Sci Rev"},{"issue":"7","key":"1402_CR19","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1007\/s00103-010-1083-2","volume":"53","author":"B-M Kurth","year":"2010","unstructured":"Kurth B-M, Schaffrath Rosario A (2010) \u00dcbergewicht und Adipositas bei Kindern und Jugendlichen in Deutschland (Overweight and obesity in children and adolescents in Germany). Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 53(7):643\u2013652","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"issue":"2","key":"1402_CR20","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1183\/09031936.00034913","volume":"43","author":"N Moual Le","year":"2014","unstructured":"Le Moual N, Carsin A-E, Siroux V, Radon K, Norback D, Toren K, Olivieri M, Urrutia I, Cazzoletti L, Jacquemin B, Benke G, Kromhout H, Mirabelli MC, Mehta AJ, Schlunssen V, Sigsgaard T, Blanc PD, Kogevinas M, Anto JM, Zock J-P (2014) Occupational exposures and uncontrolled adult-onset asthma in the European Community Respiratory Health Survey II. Eur Respir J 43(2):374\u2013386","journal-title":"Eur Respir J"},{"issue":"10","key":"1402_CR21","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1111\/j.1398-9995.2010.02375.x","volume":"65","author":"A Loerbroks","year":"2010","unstructured":"Loerbroks A, Gadinger MC, Bosch JA, Sturmer T, Amelang M (2010) Work-related stress, inability to relax after work and risk of adult asthma: a population-based cohort study. Allergy 65(10):1298\u20131305","journal-title":"Allergy"},{"issue":"3","key":"1402_CR22","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1007\/s00420-014-0962-5","volume":"88","author":"A Loerbroks","year":"2015","unstructured":"Loerbroks A, Herr RM, Li J, Bosch JA, Seegel M, Schneider M, Angerer P, Schmidt B (2015) The association of effort-reward imbalance and asthma: findings from two cross-sectional studies. Int Arch Occup Environ Health 88(3):351\u2013358","journal-title":"Int Arch Occup Environ Health"},{"issue":"4","key":"1402_CR23","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/s00420-017-1201-7","volume":"90","author":"A Loerbroks","year":"2017","unstructured":"Loerbroks A, Ding H, Han W, Wang H, Wu J-P, Yang L, Angerer P, Li J (2017) Work stress, family stress and asthma: a cross-sectional study among women in China. Int Arch Occup Environ Health 90(4):349\u2013356","journal-title":"Int Arch Occup Environ Health"},{"issue":"6","key":"1402_CR24","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1016\/j.jaci.2006.03.019","volume":"117","author":"R Marco de","year":"2006","unstructured":"Marco R de, Marcon A, Jarvis D, Accordini S, Almar E, Bugiani M, Carolei A, Cazzoletti L, Corsico A, Gislason D, Gulsvik A, Jogi R, Marinoni A, Martinez-Moratalla J, Pin I, Janson C (2006) Prognostic factors of asthma severity: a 9-year international prospective cohort study. J Allergy Clin Immunol 117(6):1249\u20131256","journal-title":"J Allergy Clin Immunol"},{"issue":"5\u20136","key":"1402_CR25","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1007\/s00103-012-1656-3","volume":"56","author":"GBM Mensink","year":"2013","unstructured":"Mensink GBM, Schienkiewitz A, Haftenberger M, Lampert T, Ziese T, Scheidt-Nave C (2013) \u00dcbergewicht und Adipositas in Deutschland: Ergebnisse der Studie zur Gesundheit Erwachsener in Deutschland (DEGS1) (Overweight and obesity in Germany: results of the German Health Interview and Examination Survey for Adults (DEGS1)). Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56(5\u20136):786\u2013794","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"issue":"1","key":"1402_CR26","doi-asserted-by":"publisher","first-page":"29","DOI":"10.2332\/allergolint.O-06-435","volume":"56","author":"K Okuyama","year":"2007","unstructured":"Okuyama K, Ohwada K, Sakurada S, Sato N, Sora I, Tamura G, Takayanagi M, Ohno I (2007) The distinctive effects of acute and chronic psychological stress on airway inflammation in a murine model of allergic asthma. Allergol Int Off J Jpn Soc Allergol 56(1):29\u201335","journal-title":"Allergol Int Off J Jpn Soc Allergol"},{"issue":"4","key":"1402_CR27","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1034\/j.1399-3003.1999.14d37.x","volume":"14","author":"J Pekkanen","year":"1999","unstructured":"Pekkanen J, Pearce N (1999) Defining asthma in epidemiological studies. Eur Respir J 14(4):951\u2013957","journal-title":"Eur Respir J"},{"issue":"3","key":"1402_CR28","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1002\/smi.1244","volume":"25","author":"K Peltzer","year":"2009","unstructured":"Peltzer K, Shisana O, Zuma K, van Wyk B, Zungu-Dirwayi N (2009) Job stress, job satisfaction and stress-related illnesses among South African educators. Stress Health 25(3):247\u2013257","journal-title":"Stress Health"},{"issue":"5","key":"1402_CR29","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1093\/occmed\/kqm055","volume":"57","author":"S Phillips","year":"2007","unstructured":"Phillips S, Sen D, McNamee R (2007) Prevalence and causes of self-reported work-related stress in head teachers. Occup Med (Oxf Engl) 57(5):367\u2013376","journal-title":"Occup Med (Oxf Engl)"},{"issue":"2","key":"1402_CR30","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1093\/occmed\/kqq200","volume":"61","author":"R Preece","year":"2011","unstructured":"Preece R (2011) Work-related stress: case definitions, prevalence and the NHS national surveys. Occup Med (Oxf Engl) 61(2):136\u2013137","journal-title":"Occup Med (Oxf Engl)"},{"key":"1402_CR31","unstructured":"R Core Team (2017) R: a language and environment for statistical computing, Vienna, Austria. \n                    https:\/\/www.R-project.org\/\n                    \n                  . Accessed 17 Jan 2018"},{"issue":"31\u201332","key":"1402_CR32","first-page":"519","volume":"113","author":"K Radon","year":"2016","unstructured":"Radon K, Nowak D, Vogelberg C, Rueff F (2016) Career advice for young allergy patients. Dtsch Arztebl Int 113(31\u201332):519\u2013524","journal-title":"Dtsch Arztebl Int"},{"issue":"11","key":"1402_CR33","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1111\/j.1398-9995.2012.02882.x.","volume":"67","author":"NH Rod","year":"2012","unstructured":"Rod NH, Kristensen TS, Lange P, Prescott E, Diderichsen F (2012) Perceived stress and risk of adult-onset asthma and other atopic disorders: a longitudinal cohort study. Allergy 67(11):1408\u20131414","journal-title":"Allergy"},{"issue":"5","key":"1402_CR34","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1016\/j.jaci.2014.07.005","volume":"134","author":"SL Rosenberg","year":"2014","unstructured":"Rosenberg SL, Miller GE, Brehm JM, Celedon JC (2014) Stress and asthma: novel insights on genetic, epigenetic, and immunologic mechanisms. J Allergy Clin Immunol 134(5):1009\u20131015","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"1402_CR35","doi-asserted-by":"publisher","first-page":"377","DOI":"10.2466\/15.14.PR0.114k20w3","volume":"114","author":"R Runeson-Broberg","year":"2014","unstructured":"Runeson-Broberg R, Norback D (2014) Work-related psychosocial stress as a risk factor for asthma, allergy, and respiratory infections in the Swedish workforce. Psychol Rep 114(2):377\u2013389","journal-title":"Psychol Rep"},{"issue":"7","key":"1402_CR36","first-page":"12","volume":"8","author":"RA Sansone","year":"2011","unstructured":"Sansone RA, Sansone LA (2011) Allergic rhinitis: relationships with anxiety and mood syndromes. Innov Clin Neurosci 8(7):12\u201317","journal-title":"Innov Clin Neurosci"},{"issue":"1","key":"1402_CR37","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1026\/\/0012-1924.45.1.8","volume":"45","author":"P Schulz","year":"1999","unstructured":"Schulz P, Schlotz W (1999) Trierer Inventar zur Erfassung von chronischem Stre\u00df (TICS): Skalenkonstruktion, teststatistische \u00dcberpr\u00fcfung und Validierung der Skala Arbeits\u00fcberlastung. Diagnostica 45(1):8\u201319","journal-title":"Diagnostica"},{"key":"1402_CR38","volume-title":"TICS: Trierer Inventar zum chronischen Stress. Manual f\u00fcr Version 3","author":"P Schulz","year":"2004","unstructured":"Schulz P, Schlotz W, Becker P (2004) TICS: Trierer Inventar zum chronischen Stress. Manual f\u00fcr Version 3. Hogrefe, G\u00f6ttingen"},{"key":"1402_CR39","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1186\/s12889-015-1954-4","volume":"15","author":"T Theorell","year":"2015","unstructured":"Theorell T, Hammarstrom A, Aronsson G, Traskman Bendz L, Grape T, Hogstedt C, Marteinsdottir I, Skoog I, Hall C (2015) A systematic review including meta-analysis of work environment and depressive symptoms. BMC Public Health 15:738","journal-title":"BMC Public Health"},{"issue":"2","key":"1402_CR40","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1378\/chest.104.2.600","volume":"104","author":"K Toren","year":"1993","unstructured":"Toren K, Brisman J, Jarvholm B (1993) Asthma and asthma-like symptoms in adults assessed by questionnaires. A literature review. Chest 104(2):600\u2013608","journal-title":"Chest"},{"key":"1402_CR41","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1196\/annals.1366.023","volume":"1088","author":"RS Vig","year":"2006","unstructured":"Vig RS, Forsythe P, Vliagoftis H (2006) The role of stress in asthma: insight from studies on the effect of acute and chronic stressors in models of airway inflammation. Ann N Y Acad Sci 1088:65\u201377","journal-title":"Ann N Y Acad Sci"},{"issue":"3","key":"1402_CR42","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1183\/09031936.04.00090303","volume":"24","author":"SK Weiland","year":"2004","unstructured":"Weiland SK, Bjorksten B, Brunekreef B, Cookson WOC, Mutius E von, Strachan DP (2004) Phase II of the international study of asthma and allergies in childhood (ISAAC II): rationale and methods. Eur Respir J 24(3):406\u2013412","journal-title":"Eur Respir J"},{"issue":"1","key":"1402_CR43","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1097\/00130832-200502000-00006","volume":"5","author":"RJ Wright","year":"2005","unstructured":"Wright RJ, Cohen RT, Cohen S (2005) The impact of stress on the development and expression of atopy. Curr Opin Allergy Clin Immunol 5(1):23\u201329","journal-title":"Curr Opin Allergy Clin Immunol"}],"container-title":["International Archives of Occupational and Environmental Health"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00420-019-01402-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00420-019-01402-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00420-019-01402-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,17]],"date-time":"2020-01-17T19:08:32Z","timestamp":1579288112000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00420-019-01402-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,18]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["1402"],"URL":"https:\/\/doi.org\/10.1007\/s00420-019-01402-x","relation":{},"ISSN":["0340-0131","1432-1246"],"issn-type":[{"value":"0340-0131","type":"print"},{"value":"1432-1246","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,18]]},"assertion":[{"value":"2 February 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 January 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 January 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"CV, DN, DW, FF, GW, JGen, JGer, KR, and TW: none. EvM: grants from German Ministry of Education and Research, during the conduct of the study; personal fees from Massachusetts Medical Society, personal fees from American Academy of Allergy, Asthma and Immunology, personal fees from Novartis Pharma SAS, personal fees from PharmaVentures, personal fees from OM Pharma, personal fees from Decision Resources, personal fees from The Chinese University of Hong Kong, personal fees from University of Copenhagen, personal fees from HAL Allergie GmbH, personal fees from \u00d6kosoziales Forum Ober\u00f6sterreich, personal fees from Mundipharma, personal fees from American Thoracic Society, personal fees from AbbVie Deutschland GmbH & Co. KG, personal fees from University of Tampere, personal fees from European Commission, personal fees from University of Turku, personal fees from University Helsinki, personal fees from Peptinnovate, outside the submitted work. WS: personal fees from Hogrefe Publishers, outside the submitted work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study was approved by the Ethical Committee of the Medical Faculty of the University of Dresden (Dresden, Germany), the Ethical Committee of the Bavarian Chamber of Physicians (Munich, Germany) and by the Ethical Committee of Ulm University (Ulm, Germany).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all study participants, or their guardians if the participants were younger than 18\u00a0years.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}