{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T19:39:56Z","timestamp":1777059596199,"version":"3.51.4"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,12,24]],"date-time":"2023-12-24T00:00:00Z","timestamp":1703376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,12,24]],"date-time":"2023-12-24T00:00:00Z","timestamp":1703376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100007259","name":"Stony Brook University","doi-asserted-by":"publisher","award":["Stony Brook Cancer Center Medical Student Summer Research Fellowship"],"award-info":[{"award-number":["Stony Brook Cancer Center Medical Student Summer Research Fellowship"]}],"id":[{"id":"10.13039\/100007259","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007259","name":"Stony Brook University","doi-asserted-by":"publisher","award":["Stony Brook Cancer Center Medical Student Summer Research Fellowship"],"award-info":[{"award-number":["Stony Brook Cancer Center Medical Student Summer Research Fellowship"]}],"id":[{"id":"10.13039\/100007259","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Arch Occup Environ Health"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1007\/s00420-023-02034-y","type":"journal-article","created":{"date-parts":[[2023,12,24]],"date-time":"2023-12-24T06:01:27Z","timestamp":1703397687000},"page":"165-177","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Occupational-related exposure to diesel exhaust and risk of leukemia: systematic review and meta-analysis of cohort studies"],"prefix":"10.1007","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6784-0058","authenticated-orcid":false,"given":"Darshi","family":"Shah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"DeStefano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Collatuzzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Teglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Boffetta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,12,24]]},"reference":[{"issue":"1","key":"2034_CR1","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s12989-019-0306-4","volume":"16","author":"MHG Andersen","year":"2019","unstructured":"Andersen MHG, Frederiksen M, Saber AT et al (2019) Health effects of exposure to diesel exhaust in diesel-powered trains. Part Fibre Toxicol 16(1):21","journal-title":"Part Fibre Toxicol"},{"issue":"11","key":"2034_CR2","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1093\/jnci\/djs035","volume":"104","author":"MD Attfield","year":"2012","unstructured":"Attfield MD, Schleiff PL, Lubin JH et al (2012) The diesel exhaust in miners study: a cohort mortality study with emphasis on lung cancer. J Natl Cancer Inst 104(11):869\u2013883","journal-title":"J Natl Cancer Inst"},{"issue":"7","key":"2034_CR3","first-page":"483","volume":"45","author":"R Balarajan","year":"1988","unstructured":"Balarajan R, McDowall ME (1988) Professional drivers in London: a mortality study. Br J Ind Med 45(7):483\u2013486","journal-title":"Br J Ind Med"},{"issue":"5","key":"2034_CR4","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1002\/ajim.4700150507","volume":"15","author":"AP Bender","year":"1989","unstructured":"Bender AP, Parker DL, Johnson RA et al (1989) Minnesota highway maintenance worker study: cancer mortality. Am J Ind Med 15(5):545\u2013556","journal-title":"Am J Ind Med"},{"issue":"11","key":"2034_CR5","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1177\/216507991005801104","volume":"58","author":"J Birdsey","year":"2010","unstructured":"Birdsey J, Alterman T, Li J, Petersen MR, Sestito J (2010) Mortality among members of a truck driver trade association. AAOHN J 58(11):473\u2013480","journal-title":"AAOHN J"},{"key":"2034_CR6","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1097\/01.jom.0000141669.08765.ab","volume":"46","author":"P Boffetta","year":"2004","unstructured":"Boffetta P (2004) Risk of acute myeloid leukemia after exposure to diesel exhaust: a review of the epidemiologic evidence. J Occup Environ Med 46:1076\u20131083","journal-title":"J Occup Environ Med"},{"issue":"4","key":"2034_CR7","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1002\/ajim.4700140405","volume":"14","author":"P Boffetta","year":"1988","unstructured":"Boffetta P, Stellman SD, Garfinkel L (1988) Diesel exhaust exposure and mortality among males in the American cancer society prospective study. Am J Ind Med 14(4):403\u2013415","journal-title":"Am J Ind Med"},{"issue":"4","key":"2034_CR8","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1023\/A:1011262105972","volume":"12","author":"P Boffetta","year":"2001","unstructured":"Boffetta P, Dosemeci M, Gridley G, Bath H, Moradi T, Silverman D (2001) Occupational exposure to diesel engine emissions and risk of cancer in Swedish men and women. Cancer Causes Control 12(4):365\u2013374","journal-title":"Cancer Causes Control"},{"issue":"22","key":"2034_CR9","doi-asserted-by":"publisher","first-page":"6589","DOI":"10.3390\/s20226589","volume":"20","author":"A Bogdanowicz","year":"2020","unstructured":"Bogdanowicz A, Kniaziewicz T (2020) Marine diesel engine exhaust emissions measured in ship\u2019s dynamic operating conditions. Sensors (basel) 20(22):6589","journal-title":"Sensors (basel)"},{"issue":"24","key":"2034_CR10","doi-asserted-by":"publisher","first-page":"1827","DOI":"10.1093\/jnci\/djr483","volume":"103","author":"VJ Cogliano","year":"2011","unstructured":"Cogliano VJ, Baan R, Straif K et al (2011) Preventable exposures associated with human cancers. J Natl Cancer Inst 103(24):1827\u20131839","journal-title":"J Natl Cancer Inst"},{"key":"2034_CR11","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.ED000142","author":"M Cumpston","year":"2019","unstructured":"Cumpston M, Li T, Page MJ et al (2019) Updated guidance for trusted systematic reviews: a new edition of the cochrane handbook for systematic reviews of interventions. Cochrane Database Syst Rev. https:\/\/doi.org\/10.1002\/14651858.ED000142","journal-title":"Cochrane Database Syst Rev"},{"issue":"3","key":"2034_CR12","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","volume":"7","author":"R DerSimonian","year":"1986","unstructured":"DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7(3):177\u2013188","journal-title":"Control Clin Trials"},{"issue":"7109","key":"2034_CR13","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","volume":"315","author":"M Egger","year":"1997","unstructured":"Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315(7109):629\u2013634","journal-title":"BMJ"},{"issue":"5","key":"2034_CR14","first-page":"337","volume":"49","author":"E Gub\u00e9ran","year":"1992","unstructured":"Gub\u00e9ran E, Usel M, Raymond L, Bolay J, Fioretta G, Puissant J (1992) Increased risk for lung cancer and for cancer of the gastrointestinal tract among Geneva professional drivers. Br J Ind Med 49(5):337\u2013344","journal-title":"Br J Ind Med"},{"issue":"2","key":"2034_CR15","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1002\/ijc.20263","volume":"111","author":"J Guo","year":"2004","unstructured":"Guo J, Kauppinen T, Kyyr\u00f6nen P, Heikkil\u00e4 P, Lindbohm ML, Pukkala E (2004) Risk of esophageal, ovarian, testicular, kidney and bladder cancers and leukemia among finnish workers exposed to diesel or gasoline engine exhaust. Int J Cancer 111(2):286\u2013292","journal-title":"Int J Cancer"},{"issue":"1","key":"2034_CR16","doi-asserted-by":"publisher","first-page":"22","DOI":"10.5271\/sjweh.2178","volume":"12","author":"L Gustafsson","year":"1986","unstructured":"Gustafsson L, Wall S, Larsson LG, Skog B (1986) Mortality and cancer incidence among Swedish dock workers\u2013a retrospective cohort study. Scand J Work Environ Health 12(1):22\u201326","journal-title":"Scand J Work Environ Health"},{"issue":"5","key":"2034_CR17","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1002\/ajim.4700230514","volume":"23","author":"ES Hansen","year":"1993","unstructured":"Hansen ES (1993) A follow-up study on the mortality of truck drivers. Am J Ind Med 23(5):811\u2013821","journal-title":"Am J Ind Med"},{"issue":"11","key":"2034_CR18","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1002\/sim.1186","volume":"21","author":"JP Higgins","year":"2002","unstructured":"Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21(11):1539\u20131558","journal-title":"Stat Med"},{"issue":"6","key":"2034_CR19","first-page":"1015","volume":"70","author":"GR Howe","year":"1983","unstructured":"Howe GR, Fraser D, Lindsay J, Presnal B, Yu SZ (1983) Cancer mortality (1965\u201377) in relation to diesel fume and coal exposure in a cohort of retired railway workers. J Natl Cancer Inst 70(6):1015\u20131019","journal-title":"J Natl Cancer Inst"},{"issue":"11","key":"2034_CR20","doi-asserted-by":"publisher","first-page":"777","DOI":"10.7326\/M14-2385","volume":"162","author":"B Hutton","year":"2015","unstructured":"Hutton B, Salanti G, Caldwell DM et al (2015) The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Ann Intern Med 162(11):777\u2013784","journal-title":"Ann Intern Med"},{"key":"2034_CR21","unstructured":"International Agency for Research on Cancer. (2014) Diesel and gasoline engine exhaust. In: IARC Monographs on the evaluation of carcinogenic risks to humans, Diesel and gasoline engine exhaust and some nitroarenes. Lyon: International Agency for Research on Cancer, Vol. 105. p. 39\u2013486."},{"key":"2034_CR22","unstructured":"Kennedy D, Bates RR, Watson AY (1988) Assessment of carcinogenicity: generic issues and their application to diesel exhaust. In: Air pollution, the automobile, and public health. National Academies Press"},{"key":"2034_CR23","doi-asserted-by":"publisher","DOI":"10.5620\/eht.e2014009","volume":"29","author":"JH Leem","year":"2014","unstructured":"Leem JH, Jang YK (2014) Increase of diesel car raises health risk in spite of recent development in engine technology. Environ Health Toxicol 29:e2014009","journal-title":"Environ Health Toxicol"},{"issue":"2","key":"2034_CR24","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1093\/carcin\/bgr297","volume":"33","author":"CM McHale","year":"2012","unstructured":"McHale CM, Zhang L, Smith MT (2012) Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessment. Carcinogenesis 33(2):240\u2013252","journal-title":"Carcinogenesis"},{"issue":"9","key":"2034_CR25","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1136\/oem.2009.050377","volume":"67","author":"DF Merlo","year":"2010","unstructured":"Merlo DF, Stagi E, Fontana V et al (2010) A historical mortality study among bus drivers and bus maintenance workers exposed to urban air pollutants in the city of Genoa. Italy Occup Environ Med 67(9):611\u2013619","journal-title":"Italy Occup Environ Med"},{"issue":"1","key":"2034_CR26","doi-asserted-by":"publisher","first-page":"e14","DOI":"10.1016\/S2352-3026(17)30232-6","volume":"5","author":"A Miranda-Filho","year":"2018","unstructured":"Miranda-Filho A, Pi\u00f1eros M, Ferlay J, Soerjomataram I, Monnereau A, Bray F (2018) Epidemiological patterns of leukaemia in 184 countries: a population-based study. Lancet Haematol 5(1):e14\u2013e24","journal-title":"Lancet Haematol"},{"issue":"7","key":"2034_CR27","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1097\/01.NAJ.0000451683.66447.89","volume":"114","author":"Z Munn","year":"2014","unstructured":"Munn Z, Tufanaru C, Aromataris E (2014) JBI\u2019s systematic reviews: data extraction and synthesis. Am J Nurs 114(7):49\u201354","journal-title":"Am J Nurs"},{"issue":"5","key":"2034_CR28","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1136\/oem.51.5.330","volume":"51","author":"P Nokso-Koivisto","year":"1994","unstructured":"Nokso-Koivisto P, Pukkala E (1994) Past exposure to asbestos and combustion products and incidence of cancer among Finnish locomotive drivers. Occup Environ Med 51(5):330\u2013334","journal-title":"Occup Environ Med"},{"issue":"2","key":"2034_CR29","doi-asserted-by":"publisher","first-page":"203","DOI":"10.15283\/ijsc21178","volume":"15","author":"HS Park","year":"2022","unstructured":"Park HS, Oh MK, Lee JW et al (2022) Diesel exhaust particles impair therapeutic effect of human Wharton\u2019s Jelly-derived mesenchymal stem cells against experimental colitis through ROS\/ERK\/cFos Signaling pathway. Int J Stem Cells 15(2):203\u2013216","journal-title":"Int J Stem Cells"},{"issue":"6","key":"2034_CR30","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1097\/01.NAJ.0000450430.97383.64","volume":"114","author":"K Porritt","year":"2014","unstructured":"Porritt K, Gomersall J, Lockwood C (2014) JBI\u2019s Systematic reviews: study selection and critical appraisal. Am J Nurs 114(6):47\u201352","journal-title":"Am J Nurs"},{"issue":"5","key":"2034_CR31","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1080\/02841860902913546","volume":"48","author":"E Pukkala","year":"2009","unstructured":"Pukkala E, Martinsen JI, Lynge E et al (2009) Occupation and cancer \u2013 follow-up of 15 million people in five Nordic countries. Acta Oncol 48(5):646\u2013790","journal-title":"Acta Oncol"},{"issue":"5","key":"2034_CR32","doi-asserted-by":"publisher","first-page":"312","DOI":"10.5271\/sjweh.1697","volume":"17","author":"V Rafnsson","year":"1991","unstructured":"Rafnsson V, Gunnarsd\u00f3ttir H (1991) Mortality among professional drivers. Scand J Work Environ Health 17(5):312\u2013317","journal-title":"Scand J Work Environ Health"},{"issue":"3","key":"2034_CR33","first-page":"340","volume":"40","author":"L Rushton","year":"1983","unstructured":"Rushton L, Alderson MR, Nagarajah CR (1983) Epidemiological survey of maintenance workers in London transport executive bus garages and Chiswick Works. Br J Ind Med 40(3):340\u2013345","journal-title":"Br J Ind Med"},{"issue":"3","key":"2034_CR34","first-page":"320","volume":"41","author":"MB Schenker","year":"1984","unstructured":"Schenker MB, Smith T, Mu\u00f1oz A, Woskie S, Speizer FE (1984) Diesel exposure and mortality among railway workers: results of a pilot study. Br J Ind Med 41(3):320\u2013327","journal-title":"Br J Ind Med"},{"issue":"12","key":"2034_CR35","doi-asserted-by":"publisher","first-page":"4398","DOI":"10.3390\/ijerph17124398","volume":"17","author":"J Shin","year":"2020","unstructured":"Shin J, Kim B, Kim HR (2020) Characteristics of occupational exposure to diesel engine exhaust for shipyard transporter signal workers. Int J Environ Res Public Health 17(12):4398","journal-title":"Int J Environ Res Public Health"},{"issue":"9","key":"2034_CR36","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1136\/oem.55.9.594","volume":"55","author":"H Soll-Johanning","year":"1998","unstructured":"Soll-Johanning H, Bach E, Olsen JH, T\u00fcchsen F (1998) Cancer incidence in urban bus drivers and tramway employees: a retrospective cohort study. Occup Environ Med 55(9):594\u2013598","journal-title":"Occup Environ Med"},{"issue":"3","key":"2034_CR37","first-page":"307","volume":"35","author":"SK Van Den Eeden","year":"1993","unstructured":"Van Den Eeden SK, Friedman GD (1993) Exposure to engine exhaust and risk of subsequent cancer. J Occup Med 35(3):307\u2013311","journal-title":"J Occup Med"},{"issue":"11","key":"2034_CR38","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1136\/oemed-2019-105847","volume":"76","author":"J Volk","year":"2019","unstructured":"Volk J, Heck JE, Schmiegelow K, Hansen J (2019) Parental occupational exposure to diesel engine exhaust in relation to childhood leukaemia and central nervous system cancers: a register-based nested case-control study in Denmark 1968\u20132016. Occup Environ Med 76(11):809\u2013817","journal-title":"Occup Environ Med"},{"issue":"4","key":"2034_CR39","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","volume":"61","author":"E von Elm","year":"2008","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP (2008) The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol 61(4):344\u2013349","journal-title":"J Clin Epidemiol"},{"key":"2034_CR40","volume-title":"Diesel exhaust reference module in biomedical sciences","author":"MJ Wernke","year":"2022","unstructured":"Wernke MJ (2022) Diesel exhaust reference module in biomedical sciences. Elsevier"},{"issue":"7","key":"2034_CR41","first-page":"435","volume":"42","author":"O Wong","year":"1985","unstructured":"Wong O, Morgan RW, Kheifets L, Larson SR, Whorton MD (1985) Mortality among members of a heavy construction equipment operators union with potential exposure to diesel exhaust emissions. Br J Ind Med 42(7):435\u2013448","journal-title":"Br J Ind Med"}],"container-title":["International Archives of Occupational and Environmental Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00420-023-02034-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00420-023-02034-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00420-023-02034-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T08:05:26Z","timestamp":1708675526000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00420-023-02034-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,24]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["2034"],"URL":"https:\/\/doi.org\/10.1007\/s00420-023-02034-y","relation":{},"ISSN":["0340-0131","1432-1246"],"issn-type":[{"value":"0340-0131","type":"print"},{"value":"1432-1246","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,24]]},"assertion":[{"value":"4 September 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 November 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 December 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"PB acted as expert witness in litigation involving DE exposure and leukemia risk, unrelated to current work. Other authors have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This project was based on publicly available data; no permission was needed from an institutional review board.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}