{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T17:55:43Z","timestamp":1775670943213,"version":"3.50.1"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2009,12,6]],"date-time":"2009-12-06T00:00:00Z","timestamp":1260057600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Appl Physiol"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1007\/s00421-009-1294-0","type":"journal-article","created":{"date-parts":[[2009,12,5]],"date-time":"2009-12-05T06:04:58Z","timestamp":1259993098000},"page":"987-997","source":"Crossref","is-referenced-by-count":32,"title":["HPA and SAS responses to increasing core temperature during uncompensable exertional heat stress in trained and untrained males"],"prefix":"10.1007","volume":"108","author":[{"given":"Heather E.","family":"Wright","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glen A.","family":"Selkirk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom M.","family":"McLellan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,12,6]]},"reference":[{"key":"1294_CR1","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1530\/eje.0.1330635","volume":"133","author":"CJ Auernhammer","year":"1995","unstructured":"Auernhammer CJ, Strasburger CJ (1995) Effects of growth hormone and insulin-like growth factor I on the immune system. Eur J Endocrinol 133:635\u2013645","journal-title":"Eur J Endocrinol"},{"key":"1294_CR2","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1055\/s-2007-971895","volume":"19","author":"I Brenner","year":"1998","unstructured":"Brenner I, Shek PN, Zamecnik J, Shephard RJ (1998) Stress hormones and the immunological responses to heat and exercise. Int J Sports Med 19:130\u2013143","journal-title":"Int J Sports Med"},{"key":"1294_CR3","first-page":"193","volume":"19","author":"JMH Buckler","year":"1973","unstructured":"Buckler JMH (1973) The relationship between changes in plasma growth hormone levels and body temperature occurring with exercise in man. Biomedicine 19:193\u2013197","journal-title":"Biomedicine"},{"key":"1294_CR4","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1123\/ijsnem.10.4.361","volume":"10","author":"DJ Casa","year":"2000","unstructured":"Casa DJ, Maresh CM, Armstrong LE, Kavouras SA, Herrera-Soto JA, Hacker FT Jr, Scheett TP, Stoppani J (2000) Intravenous versus oral rehydration during a brief period: stress hormone responses to subsequent exhaustive exercise in the heat. Int J Sport Nutr Exerc Metab 10:361\u2013374","journal-title":"Int J Sport Nutr Exerc Metab"},{"key":"1294_CR5","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1152\/jappl.1998.84.5.1731","volume":"84","author":"SS Cheung","year":"1998","unstructured":"Cheung SS, McLellan TM (1998) Heat acclimation, aerobic fitness, and hydration effects on tolerance during uncompensable heat stress. J Appl Physiol 84:1731\u20131739","journal-title":"J Appl Physiol"},{"key":"1294_CR6","doi-asserted-by":"crossref","first-page":"329","DOI":"10.2165\/00007256-200029050-00004","volume":"29","author":"SS Cheung","year":"2000","unstructured":"Cheung SS, McLellan TM, Tenaglia S (2000) The thermophysiology of uncompensable heat stress. Physiological manipulations and individual characteristics. Sports Med 29:329\u2013359","journal-title":"Sports Med"},{"key":"1294_CR7","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1152\/jappl.1996.81.2.822","volume":"81","author":"MC Cross","year":"1996","unstructured":"Cross MC, Radomski MW, VanHelder WP, Rhind SG, Shephard RJ (1996) Endurance exercise with and without a thermal clamp: effects on leukocytes and leukocyte subsets. J Appl Physiol 81:822\u2013829","journal-title":"J Appl Physiol"},{"key":"1294_CR8","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0026-0495(89)90253-9","volume":"38","author":"PA Deuster","year":"1989","unstructured":"Deuster PA, Chrousos GP, Luger A, DeBolt JE, Bernier LL, Trostmann UH, Kyle SB, Montgomery LC, Loriaux DL (1989) Hormonal and metabolic responses of untrained, moderately trained, and highly trained men to three exercise intensities. Metabolism 38:141\u2013148","journal-title":"Metabolism"},{"key":"1294_CR9","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1046\/j.1365-2265.1998.00334.x","volume":"48","author":"M Duclos","year":"1998","unstructured":"Duclos M, Corcuff JB, Arsac L, Moreau-Gaudry F, Rashedi M, Roger P, Tabarin A, Manier G (1998) Corticotroph axis sensitivity after exercise in endurance-trained athletes. Clin Endocrinol (Oxf) 48:493\u2013501","journal-title":"Clin Endocrinol (Oxf)"},{"key":"1294_CR10","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1530\/eje.0.1440363","volume":"144","author":"M Duclos","year":"2001","unstructured":"Duclos M, Corcuff JB, Pehourcq F, Tabarin A (2001) Decreased pituitary sensitivity to glucocorticoids in endurance-trained men. Eur J Endocrinol 144:363\u2013368","journal-title":"Eur J Endocrinol"},{"key":"1294_CR11","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1152\/jappl.1997.82.4.1126","volume":"82","author":"CW Ho","year":"1997","unstructured":"Ho CW, Beard JL, Farrell PA, Minson CT, Kenney WL (1997) Age, fitness, and regional blood flow during exercise in the heat. J Appl Physiol 82:1126\u20131135","journal-title":"J Appl Physiol"},{"key":"1294_CR12","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s004210050321","volume":"77","author":"M Kjaer","year":"1998","unstructured":"Kjaer M (1998) Adrenal medulla and exercise training. Eur J Appl Physiol Occup Physiol 77:195\u2013199","journal-title":"Eur J Appl Physiol Occup Physiol"},{"key":"1294_CR13","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1152\/jappl.1985.59.4.1061","volume":"59","author":"M Kjaer","year":"1985","unstructured":"Kjaer M, Christensen NJ, Sonne B, Richter EA, Galbo H (1985) Effect of exercise on epinephrine turnover in trained and untrained male subjects. J Appl Physiol 59:1061\u20131067","journal-title":"J Appl Physiol"},{"key":"1294_CR14","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.1152\/jappl.1991.71.6.2138","volume":"71","author":"KK Kraning II","year":"1991","unstructured":"Kraning KK II, Gonzalez RR (1991) Physiological consequences of intermittent exercise during compensable and uncompensable heat stress. J Appl Physiol 71:2138\u20132145","journal-title":"J Appl Physiol"},{"key":"1294_CR15","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S0031-6997(25)06843-7","volume":"32","author":"SZ Langer","year":"1980","unstructured":"Langer SZ (1980) Presynaptic regulation of the release of catecholamines. Pharmacol Rev 32:337\u2013362","journal-title":"Pharmacol Rev"},{"key":"1294_CR16","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1210\/jcem-66-2-343","volume":"66","author":"MH Laudat","year":"1988","unstructured":"Laudat MH, Cerdas S, Fournier C, Guiban D, Guilhaume B, Luton JP (1988) Salivary cortisol measurement: a practical approach to assess pituitary-adrenal function. J Clin Endocrinol Metab 66:343\u2013348","journal-title":"J Clin Endocrinol Metab"},{"key":"1294_CR17","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1152\/jappl.1993.75.2.668","volume":"75","author":"U Leuenberger","year":"1993","unstructured":"Leuenberger U, Sinoway L, Gubin S, Gaul L, Davis D, Zelis R (1993) Effects of exercise intensity and duration on norepinephrine spillover and clearance in humans. J Appl Physiol 75:668\u2013674","journal-title":"J Appl Physiol"},{"key":"1294_CR18","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1159\/000126912","volume":"56","author":"A Luger","year":"1992","unstructured":"Luger A, Watschinger B, Deuster P, Svoboda T, Clodi M, Chrousos GP (1992) Plasma growth hormone and prolactin responses to graded levels of acute exercise and to a lactate infusion. Neuroendocrinology 56:112\u2013117","journal-title":"Neuroendocrinology"},{"key":"1294_CR19","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/BF02376767","volume":"74","author":"TM McLellan","year":"1996","unstructured":"McLellan TM, Pope JI, Cain JB, Cheung SS (1996) Effects of metabolic rate and ambient vapour pressure on heat strain in protective clothing. Eur J Appl Physiol Occup Physiol 74:518\u2013527","journal-title":"Eur J Appl Physiol Occup Physiol"},{"key":"1294_CR20","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.1365-2265.1989.tb00271.x","volume":"30","author":"N Moller","year":"1989","unstructured":"Moller N, Beckwith R, Butler PC, Christensen NJ, Orskov H, Alberti KG (1989) Metabolic and hormonal responses to exogenous hyperthermia in man. Clin Endocrinol (Oxf) 30:651\u2013660","journal-title":"Clin Endocrinol (Oxf)"},{"key":"1294_CR21","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1113\/jphysiol.2002.030023","volume":"545","author":"L Nybo","year":"2002","unstructured":"Nybo L, Secher NH, Nielsen B (2002) Inadequate heat release from the human brain during prolonged exercise with hyperthermia. J Physiol 545:697\u2013704","journal-title":"J Physiol"},{"key":"1294_CR22","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/00140137708931642","volume":"20","author":"KB Pandolf","year":"1977","unstructured":"Pandolf KB, Burse RL, Goldman RF (1977) Role of physical fitness in heat acclimatisation, decay and reinduction. Ergonomics 20:399\u2013408","journal-title":"Ergonomics"},{"key":"1294_CR23","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1249\/00005768-199410000-00015","volume":"26","author":"GA Ponjee","year":"1994","unstructured":"Ponjee GA, De Rooy HA, Vader HL (1994) Androgen turnover during marathon running. Med Sci Sports Exerc 26:1274\u20131277","journal-title":"Med Sci Sports Exerc"},{"key":"1294_CR24","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1139\/y98-045","volume":"76","author":"MW Radomski","year":"1998","unstructured":"Radomski MW, Cross M, Buguet A (1998) Exercise-induced hyperthermia and hormonal responses to exercise. Can J Physiol Pharmacol 76:547\u2013552","journal-title":"Can J Physiol Pharmacol"},{"key":"1294_CR25","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1152\/jappl.1999.87.3.1178","volume":"87","author":"SG Rhind","year":"1999","unstructured":"Rhind SG, Gannon GA, Shek PN, Brenner IK, Severs Y, Zamecnik J, Buguet A, Natale VM, Shephard RJ, Radomski MW (1999) Contribution of exertional hyperthermia to sympathoadrenal-mediated lymphocyte subset redistribution. J Appl Physiol 87:1178\u20131185","journal-title":"J Appl Physiol"},{"key":"1294_CR26","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1080\/02656730410001670651","volume":"20","author":"SG Rhind","year":"2004","unstructured":"Rhind SG, Gannon GA, Shephard RJ, Buguet A, Shek PN, Radomski MW (2004) Cytokine induction during exertional hyperthermia is abolished by core temperature clamping: neuroendocrine regulatory mechanisms. Int J Hyperthermia 20:503\u2013516","journal-title":"Int J Hyperthermia"},{"key":"1294_CR27","first-page":"189","volume":"15","author":"D Robertshaw","year":"1977","unstructured":"Robertshaw D (1977) Role of the adrenal medulla in thermoregulation. Int Rev Physiol 15:189\u2013215","journal-title":"Int Rev Physiol"},{"key":"1294_CR28","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1152\/jappl.1966.21.6.1757","volume":"21","author":"B Saltin","year":"1966","unstructured":"Saltin B, Hermansen L (1966) Esophageal, rectal, and muscle temperature during exercise. J Appl Physiol 21:1757\u20131762","journal-title":"J Appl Physiol"},{"key":"1294_CR29","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1152\/jappl.2001.91.5.2055","volume":"91","author":"GA Selkirk","year":"2001","unstructured":"Selkirk GA, McLellan TM (2001) Influence of aerobic fitness and body fatness on tolerance to uncompensable heat stress. J Appl Physiol 91:2055\u20132063","journal-title":"J Appl Physiol"},{"key":"1294_CR30","doi-asserted-by":"crossref","first-page":"R611","DOI":"10.1152\/ajpregu.00917.2007","volume":"295","author":"GA Selkirk","year":"2008","unstructured":"Selkirk GA, McLellan TM, Wright HE, Rhind SG (2008) Mild endotoxemia, NF-kappaB translocation, and cytokine increase during exertional heat stress in trained and untrained individuals. Am J Physiol Regul Integr Comp Physiol 295:R611\u2013R623","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"1294_CR31","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1080\/00140130412331303911","volume":"48","author":"DL Smith","year":"2005","unstructured":"Smith DL, Petruzzello SJ, Chludzinski MA, Reed JJ, Woods JA (2005) Selected hormonal and immunological responses to strenuous live-fire firefighting drills. Ergonomics 48:55\u201365","journal-title":"Ergonomics"},{"issue":"Suppl 2","key":"1294_CR32","first-page":"333","volume":"3","author":"CA Stratakis","year":"2006","unstructured":"Stratakis CA (2006) Cortisol and growth hormone: clinical implications of a complex, dynamic relationship. Pediatr Endocrinol Rev 3(Suppl 2):333\u2013338","journal-title":"Pediatr Endocrinol Rev"},{"key":"1294_CR33","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.cardiores.2003.11.037","volume":"61","author":"AD Struthers","year":"2004","unstructured":"Struthers AD, MacDonald TM (2004) Review of aldosterone- and angiotensin II-induced target organ damage and prevention. Cardiovasc Res 61:663\u2013670","journal-title":"Cardiovasc Res"},{"key":"1294_CR34","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s004210100420","volume":"85","author":"O Tissandier","year":"2001","unstructured":"Tissandier O, Peres G, Fiet J, Piette F (2001) Testosterone, dehydroepiandrosterone, insulin-like growth factor 1, and insulin in sedentary and physically trained aged men. Eur J Appl Physiol 85:177\u2013184","journal-title":"Eur J Appl Physiol"},{"key":"1294_CR35","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s00421-005-1380-x","volume":"94","author":"MS Tremblay","year":"2005","unstructured":"Tremblay MS, Copeland JL, Van Helder W (2005) Influence of exercise duration on post-exercise steroid hormone responses in trained males. Eur J Appl Physiol 94:505\u2013513","journal-title":"Eur J Appl Physiol"},{"key":"1294_CR36","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1152\/japplphysiol.00484.2007","volume":"103","author":"M Whitham","year":"2007","unstructured":"Whitham M, Laing SJ, Jackson A, Maassen N, Walsh NP (2007) Effect of exercise with and without a thermal clamp on the plasma heat shock protein 72 response. J Appl Physiol 103:1251\u20131256","journal-title":"J Appl Physiol"},{"key":"1294_CR37","first-page":"106","volume":"42","author":"J Zamecnik","year":"1997","unstructured":"Zamecnik J (1997) Quantitation of Epinephrine, Norepinephrine, Dopamine, Metanephrine, and Normetanephrine in human plasma using negative ion chemical ionization GC-MS. Can J Anal Sci Spectroscopy 42:106\u2013112","journal-title":"Can J Anal Sci Spectroscopy"}],"container-title":["European Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00421-009-1294-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00421-009-1294-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00421-009-1294-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T16:58:52Z","timestamp":1739465932000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00421-009-1294-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12,6]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["1294"],"URL":"https:\/\/doi.org\/10.1007\/s00421-009-1294-0","relation":{},"ISSN":["1439-6319","1439-6327"],"issn-type":[{"value":"1439-6319","type":"print"},{"value":"1439-6327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12,6]]}}}