{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T22:37:27Z","timestamp":1788907047874,"version":"build-2803163510"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2018,7,9]],"date-time":"2018-07-09T00:00:00Z","timestamp":1531094400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2018,7,9]],"date-time":"2018-07-09T00:00:00Z","timestamp":1531094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20614473"],"award-info":[{"award-number":["20614473"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Appl Physiol"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1007\/s00421-018-3933-9","type":"journal-article","created":{"date-parts":[[2018,7,9]],"date-time":"2018-07-09T09:25:05Z","timestamp":1531128305000},"page":"1997-2005","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Contralateral repeated bout effect after eccentric exercise on muscular activation"],"prefix":"10.1007","volume":"118","author":[{"given":"Yosuke","family":"Tsuchiya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Nakazato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2497-0250","authenticated-orcid":false,"given":"Eisuke","family":"Ochi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,7,9]]},"reference":[{"issue":"4","key":"3933_CR1","doi-asserted-by":"publisher","first-page":"1578","DOI":"10.1152\/jappl.1992.73.4.1578","volume":"73","author":"GR Adams","year":"1992","unstructured":"Adams GR, Duvoisin MR, Dudley GA (1992) Magnetic resonance imaging and electromyography as indexes of muscle function. J Appl Physiol (1985) 73(4):1578\u20131583","journal-title":"J Appl Physiol (1985)"},{"issue":"2","key":"3933_CR2","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1152\/jappl.1993.74.2.532","volume":"74","author":"GR Adams","year":"1993","unstructured":"Adams GR, Harris RT, Woodard D, Dudley GA (1993) Mapping of electrical muscle stimulation using MRI. J Appl Physiol (1985) 74(2):532\u2013537. \n                    https:\/\/doi.org\/10.1152\/jappl.1993.74.2.532","journal-title":"J Appl Physiol (1985)"},{"issue":"4","key":"3933_CR3","doi-asserted-by":"publisher","first-page":"621","DOI":"10.7600\/jpfsm.1.621","volume":"1","author":"H Akima","year":"2012","unstructured":"Akima H (2012) Evaluation of functional properties of skeletal muscle using functional magnetic resonance imaging (fMRI). J Phys Fit Sports Med 1(4):621\u2013630","journal-title":"J Phys Fit Sports Med"},{"issue":"5","key":"3933_CR4","doi-asserted-by":"publisher","first-page":"1514","DOI":"10.1152\/japplphysiol.00531.2006","volume":"101","author":"TJ Carroll","year":"2006","unstructured":"Carroll TJ, Herbert RD, Munn J, Lee M, Gandevia SC (2006) Contralateral effects of unilateral strength training: evidence and possible mechanisms. J Appl Physiol (1985) 101(5):1514\u20131522. \n                    https:\/\/doi.org\/10.1152\/japplphysiol.00531.2006","journal-title":"J Appl Physiol (1985)"},{"issue":"2","key":"3933_CR5","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s00421-009-1016-7","volume":"106","author":"TC Chen","year":"2009","unstructured":"Chen TC, Chen HL, Lin MJ, Wu CJ, Nosaka K (2009) Muscle damage responses of the elbow flexors to four maximal eccentric exercise bouts performed every 4 weeks. Eur J Appl Physiol 106(2):267\u2013275. \n                    https:\/\/doi.org\/10.1007\/s00421-009-1016-7","journal-title":"Eur J Appl Physiol"},{"issue":"2","key":"3933_CR6","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1007\/s00421-010-1648-7","volume":"111","author":"TC Chen","year":"2011","unstructured":"Chen TC, Lin KY, Chen HL, Lin MJ, Nosaka K (2011) Comparison in eccentric exercise-induced muscle damage among four limb muscles. Eur J Appl Physiol 111(2):211\u2013223. \n                    https:\/\/doi.org\/10.1007\/s00421-010-1648-7","journal-title":"Eur J Appl Physiol"},{"issue":"10","key":"3933_CR7","doi-asserted-by":"publisher","first-page":"2030","DOI":"10.1249\/MSS.0000000000000991","volume":"48","author":"TC Chen","year":"2016","unstructured":"Chen TC, Chen HL, Lin MJ, Yu HI, Nosaka K (2016) Contralateral repeated bout effect of eccentric exercise of the elbow flexors. Med Sci Sports Exerc 48(10):2030\u20132039. \n                    https:\/\/doi.org\/10.1249\/MSS.0000000000000991","journal-title":"Med Sci Sports Exerc"},{"issue":"11 Suppl","key":"3933_CR8","doi-asserted-by":"publisher","first-page":"S52","DOI":"10.1097\/00002060-200211001-00007","volume":"81","author":"PM Clarkson","year":"2002","unstructured":"Clarkson PM, Hubal MJ (2002) Exercise-induced muscle damage in humans. Am J Phys Med Rehabil 81(11 Suppl):S52\u2013S69. \n                    https:\/\/doi.org\/10.1097\/01.phm.0000029772.45258.43","journal-title":"Am J Phys Med Rehabil"},{"issue":"3","key":"3933_CR9","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1139\/h99-020","volume":"24","author":"PM Clarkson","year":"1999","unstructured":"Clarkson PM, Sayers SP (1999) Etiology of exercise-induced muscle damage. Can J Appl Physiol 24(3):234\u2013248","journal-title":"Can J Appl Physiol"},{"issue":"5","key":"3933_CR10","first-page":"512","volume":"24","author":"PM Clarkson","year":"1992","unstructured":"Clarkson PM, Nosaka K, Braun B (1992) Muscle function after exercise-induced muscle damage and rapid adaptation. Med Sci Sports Exerc 24(5):512\u2013520","journal-title":"Med Sci Sports Exerc"},{"issue":"11","key":"3933_CR11","doi-asserted-by":"publisher","first-page":"1407","DOI":"10.1152\/japplphysiol.00069.2013","volume":"116","author":"W Herzog","year":"2014","unstructured":"Herzog W (2014) Mechanisms of enhanced force production in lengthening (eccentric) muscle contractions. J Appl Physiol (1985) 116(11):1407\u20131417. \n                    https:\/\/doi.org\/10.1152\/japplphysiol.00069.2013","journal-title":"J Appl Physiol (1985)"},{"issue":"2","key":"3933_CR12","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/s00421-007-0489-5","volume":"101","author":"G Howatson","year":"2007","unstructured":"Howatson G, van Someren KA (2007) Evidence of a contralateral repeated bout effect after maximal eccentric contractions. Eur J Appl Physiol 101(2):207\u2013214. \n                    https:\/\/doi.org\/10.1007\/s00421-007-0489-5","journal-title":"Eur J Appl Physiol"},{"issue":"1","key":"3933_CR13","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1249\/JES.0000000000000095","volume":"45","author":"RD Hyldahl","year":"2017","unstructured":"Hyldahl RD, Chen TC, Nosaka K (2017) Mechanisms and mediators of the skeletal muscle repeated bout effect. Exerc Sport Sci Rev 45(1):24\u201333. \n                    https:\/\/doi.org\/10.1249\/jes.0000000000000095","journal-title":"Exerc Sport Sci Rev"},{"issue":"6","key":"3933_CR14","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1007\/s40279-013-0052-y","volume":"43","author":"ME Isner-Horobeti","year":"2013","unstructured":"Isner-Horobeti ME, Dufour SP, Vautravers P, Geny B, Coudeyre E, Richard R (2013) Eccentric exercise training: modalities, applications and perspectives. Sports Med 43(6):483\u2013512. \n                    https:\/\/doi.org\/10.1007\/s40279-013-0052-y","journal-title":"Sports Med"},{"key":"3933_CR15","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1016\/j.neuroscience.2015.05.057","volume":"300","author":"DJ Kidgell","year":"2015","unstructured":"Kidgell DJ, Frazer AK, Daly RM, Rantalainen T, Ruotsalainen I, Ahtiainen J, Avela J, Howatson G (2015) Increased cross-education of muscle strength and reduced corticospinal inhibition following eccentric strength training. Neuroscience 300:566\u2013575. \n                    https:\/\/doi.org\/10.1016\/j.neuroscience.2015.05.057","journal-title":"Neuroscience"},{"issue":"5","key":"3933_CR16","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.mri.2006.01.002","volume":"24","author":"R Kinugasa","year":"2006","unstructured":"Kinugasa R, Kawakami Y, Fukunaga T (2006) Quantitative assessment of skeletal muscle activation using muscle functional MRI. Magn Reson Imaging 24(5):639\u2013644. \n                    https:\/\/doi.org\/10.1016\/j.mri.2006.01.002","journal-title":"Magn Reson Imaging"},{"issue":"9","key":"3933_CR17","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1113\/expphysiol.2011.057562","volume":"96","author":"R Kinugasa","year":"2011","unstructured":"Kinugasa R, Kawakami Y, Sinha S, Fukunaga T (2011) Unique spatial distribution of in vivo human muscle activation. Exp Physiol 96(9):938\u2013948. \n                    https:\/\/doi.org\/10.1113\/expphysiol.2011.057562","journal-title":"Exp Physiol"},{"issue":"5","key":"3933_CR18","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1007\/s00421-016-3358-2","volume":"116","author":"K Kouzaki","year":"2016","unstructured":"Kouzaki K, Nosaka K, Ochi E, Nakazato K (2016) Increases in M-wave latency of biceps brachii after elbow flexor eccentric contractions in women. Eur J Appl Physiol 116(5):939\u2013946. \n                    https:\/\/doi.org\/10.1007\/s00421-016-3358-2","journal-title":"Eur J Appl Physiol"},{"issue":"1","key":"3933_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2165\/00007256-200737010-00001","volume":"37","author":"M Lee","year":"2007","unstructured":"Lee M, Carroll TJ (2007) Cross education: possible mechanisms for the contralateral effects of unilateral resistance training. Sports Med 37(1):1\u201314","journal-title":"Sports Med"},{"issue":"2","key":"3933_CR20","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1034\/j.1600-0838.2003.02477.x","volume":"13","author":"MP McHugh","year":"2003","unstructured":"McHugh MP (2003) Recent advances in the understanding of the repeated bout effect: the protective effect against muscle damage from a single bout of eccentric exercise. Scand J Med Sci Sports 13(2):88\u201397","journal-title":"Scand J Med Sci Sports"},{"issue":"3","key":"3933_CR21","doi-asserted-by":"publisher","first-page":"157","DOI":"10.2165\/00007256-199927030-00002","volume":"27","author":"MP McHugh","year":"1999","unstructured":"McHugh MP, Connolly DA, Eston RG, Gleim GW (1999) Exercise-induced muscle damage and potential mechanisms for the repeated bout effect. Sports Medicine 27(3):157\u2013170","journal-title":"Sports Medicine"},{"issue":"5","key":"3933_CR22","doi-asserted-by":"publisher","first-page":"1861","DOI":"10.1152\/japplphysiol.00541.2003","volume":"96","author":"J Munn","year":"2004","unstructured":"Munn J, Herbert RD, Gandevia SC (2004) Contralateral effects of unilateral resistance training: a meta-analysis. J Appl Physiol (1985) 96(5):1861\u20131866. \n                    https:\/\/doi.org\/10.1152\/japplphysiol.00541.2003","journal-title":"J Appl Physiol (1985)"},{"issue":"5","key":"3933_CR23","doi-asserted-by":"publisher","first-page":"1880","DOI":"10.1152\/japplphysiol.00559.2005","volume":"99","author":"J Munn","year":"2005","unstructured":"Munn J, Herbert RD, Hancock MJ, Gandevia SC (2005) Training with unilateral resistance exercise increases contralateral strength. J Appl Physiol (1985) 99(5):1880\u20131884. \n                    https:\/\/doi.org\/10.1152\/japplphysiol.00559.2005","journal-title":"J Appl Physiol (1985)"},{"issue":"2","key":"3933_CR24","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1519\/JSC.0b013e3181660003","volume":"22","author":"MJ Newton","year":"2008","unstructured":"Newton MJ, Morgan GT, Sacco P, Chapman DW, Nosaka K (2008) Comparison of responses to strenuous eccentric exercise of the elbow flexors between resistance-trained and untrained men. J Strength Cond Res 22(2):597\u2013607. \n                    https:\/\/doi.org\/10.1519\/JSC.0b013e3181660003","journal-title":"J Strength Cond Res"},{"issue":"2","key":"3933_CR25","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.jsams.2012.06.001","volume":"16","author":"MJ Newton","year":"2013","unstructured":"Newton MJ, Sacco P, Chapman D, Nosaka K (2013) Do dominant and non-dominant arms respond similarly to maximal eccentric exercise of the elbow flexors? J Sci Med Sport 16(2):166\u2013171. \n                    https:\/\/doi.org\/10.1016\/j.jsams.2012.06.001","journal-title":"J Sci Med Sport"},{"issue":"8","key":"3933_CR26","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1097\/00005768-199608000-00003","volume":"28","author":"K Nosaka","year":"1996","unstructured":"Nosaka K, Clarkson PM (1996) Changes in indicators of inflammation after eccentric exercise of the elbow flexors. Med Sci Sports Exerc 28(8):953\u2013961","journal-title":"Med Sci Sports Exerc"},{"issue":"1","key":"3933_CR27","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1097\/00005768-200101000-00005","volume":"33","author":"K Nosaka","year":"2001","unstructured":"Nosaka K, Sakamoto K (2001) Effect of elbow joint angle on the magnitude of muscle damage to the elbow flexors. Med Sci Sports Exerc 33(1):22\u201329","journal-title":"Med Sci Sports Exerc"},{"issue":"11\u201312","key":"3933_CR28","doi-asserted-by":"publisher","first-page":"2145","DOI":"10.1007\/s00421-016-3462-3","volume":"116","author":"E Ochi","year":"2016","unstructured":"Ochi E, Tsuchiya Y, Nosaka K (2016) Differences in post-exercise T2 relaxation time changes between eccentric and concentric contractions of the elbow flexors. Eur J Appl Physiol 116(11\u201312):2145\u20132154. \n                    https:\/\/doi.org\/10.1007\/s00421-016-3462-3","journal-title":"Eur J Appl Physiol"},{"key":"3933_CR29","first-page":"64","volume":"11","author":"J Peake","year":"2005","unstructured":"Peake J, Nosaka K, Suzuki K (2005) Characterization of inflammatory responses to eccentric exercise in humans. Exerc Immunol Rev 11:64\u201385","journal-title":"Exerc Immunol Rev"},{"issue":"22","key":"3933_CR30","doi-asserted-by":"publisher","first-page":"5631","DOI":"10.1523\/JNEUROSCI.0093-08.2008","volume":"28","author":"MA Perez","year":"2008","unstructured":"Perez MA, Cohen LG (2008) Mechanisms underlying functional changes in the primary motor cortex ipsilateral to an active hand. J Neurosci 28(22):5631\u20135640. \n                    https:\/\/doi.org\/10.1523\/jneurosci.0093-08.2008","journal-title":"J Neurosci"},{"issue":"3","key":"3933_CR31","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1007\/s00421-011-2053-6","volume":"112","author":"C Starbuck","year":"2012","unstructured":"Starbuck C, Eston RG (2012) Exercise-induced muscle damage and the repeated bout effect: evidence for cross transfer. Eur J Appl Physiol 112(3):1005\u20131013. \n                    https:\/\/doi.org\/10.1007\/s00421-011-2053-6","journal-title":"Eur J Appl Physiol"},{"issue":"3","key":"3933_CR32","doi-asserted-by":"publisher","first-page":"169","DOI":"10.3233\/IES-150578","volume":"23","author":"Y Tsuchiya","year":"2015","unstructured":"Tsuchiya Y, Kikuchi N, Shirato M, Ochi E (2015) Differences of activation pattern and damage in elbow flexor muscle after isokinetic eccentric contractions. Isokinet Exerc Sci 23(3):169\u2013175","journal-title":"Isokinet Exerc Sci"},{"issue":"6","key":"3933_CR33","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1007\/s00421-016-3373-3","volume":"116","author":"Y Tsuchiya","year":"2016","unstructured":"Tsuchiya Y, Yanagimoto K, Nakazato K, Hayamizu K, Ochi E (2016) Eicosapentaenoic and docosahexaenoic acids-rich fish oil supplementation attenuates strength loss and limited joint range of motion after eccentric contractions: a randomized, double-blind, placebo-controlled, parallel-group trial. Eur J Appl Physiol 116(6):1179\u20131188. \n                    https:\/\/doi.org\/10.1007\/s00421-016-3373-3","journal-title":"Eur J Appl Physiol"},{"key":"3933_CR34","doi-asserted-by":"publisher","first-page":"985","DOI":"10.3389\/fphys.2017.00985","volume":"8","author":"AD Vigotsky","year":"2017","unstructured":"Vigotsky AD, Halperin I, Lehman GJ, Trajano GS, Vieira TM (2017) Interpreting signal amplitudes in surface electromyography studies in sport and rehabilitation sciences. Front Physiol 8:985. \n                    https:\/\/doi.org\/10.3389\/fphys.2017.00985","journal-title":"Front Physiol"},{"issue":"4","key":"3933_CR35","doi-asserted-by":"publisher","first-page":"820","DOI":"10.1097\/00005768-200004000-00015","volume":"32","author":"GL Warren","year":"2000","unstructured":"Warren GL, Hermann KM, Ingalls CP, Masselli MR, Armstrong RB (2000) Decreased EMG median frequency during a second bout of eccentric contractions. Med Sci Sports Exerc 32(4):820\u2013829","journal-title":"Med Sci Sports Exerc"},{"issue":"11","key":"3933_CR36","doi-asserted-by":"publisher","first-page":"1473","DOI":"10.1152\/japplphysiol.00133.2013","volume":"116","author":"L Xin","year":"2014","unstructured":"Xin L, Hyldahl RD, Chipkin SR, Clarkson PM (2014) A contralateral repeated bout effect attenuates induction of NF-kappaB DNA binding following eccentric exercise. J Appl Physiol (1985) 116(11):1473\u20131480. \n                    https:\/\/doi.org\/10.1152\/japplphysiol.00133.2013","journal-title":"J Appl Physiol (1985)"}],"container-title":["European Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00421-018-3933-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00421-018-3933-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00421-018-3933-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T13:08:13Z","timestamp":1589634493000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00421-018-3933-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,9]]},"references-count":36,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["3933"],"URL":"https:\/\/doi.org\/10.1007\/s00421-018-3933-9","relation":{},"ISSN":["1439-6319","1439-6327"],"issn-type":[{"value":"1439-6319","type":"print"},{"value":"1439-6327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,9]]},"assertion":[{"value":"24 January 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 July 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}