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This study aimed to determine the influence of intraday repeated hand cooling on cold-induced vasodilation (CIVD), sympathetic activation, and finger\/hand temperature recovery. Eight males and two females (mean\u2009\u00b1\u2009SD age: 28\u2009\u00b1\u20095\u00a0year; height: 181\u2009\u00b1\u20099\u00a0cm; weight: 79.9\u2009\u00b1\u200910.4\u00a0kg) performed two 30-min hand immersions in cold (4.3\u2009\u00b1\u20090.92\u00a0\u00b0C) water in an indoor environment (18\u00a0\u00b0C). Both immersions (Imm1; Imm2) were performed on the same day and both allowed for a 10-min recovery. CIVD components were calculated for each finger (index, middle, ring) during each immersion. CIVD onset time (index, <jats:italic>p<\/jats:italic>\u2009=\u20090.546; middle, <jats:italic>p<\/jats:italic>\u2009=\u20090.727; ring, <jats:italic>p<\/jats:italic>\u2009=\u20090.873), minimum finger temperature (index, <jats:italic>p<\/jats:italic>\u2009=\u20090.634; middle, <jats:italic>p<\/jats:italic>\u2009=\u20090.493; ring, <jats:italic>p<\/jats:italic>\u2009=\u20090.575), and mean finger temperature (index, <jats:italic>p<\/jats:italic>\u2009=\u20090.986; middle, <jats:italic>p<\/jats:italic>\u2009=\u20090.953; ring, <jats:italic>p<\/jats:italic>\u2009=\u20090.637) were all similar between immersions. Recovery rates generally demonstrated similar responses as well. Findings suggest that two sequential CIVD tests analyzing the effect of prior cold exposure of the hand does not impair the CIVD response or recovery. Such findings appear promising for those venturing into cold environments where hands are likely to be repeatedly exposed to cold temperatures.<\/jats:p>","DOI":"10.1007\/s00421-023-05304-2","type":"journal-article","created":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T01:02:10Z","timestamp":1697850130000},"page":"775-781","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cold-induced vasodilation during sequential immersions of the hand"],"prefix":"10.1007","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-9301-2003","authenticated-orcid":false,"given":"Rebecca S.","family":"Weller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hein A.","family":"Daanen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca J.","family":"McClintock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas A.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy L.","family":"Dunn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas M.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,21]]},"reference":[{"issue":"8","key":"5304_CR1","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.1113\/EP087718","volume":"104","author":"B Alba","year":"2019","unstructured":"Alba B, Castellani J, Charkoudian N (2019) Cold-induced cutaneous vasoconstriction in humans: function, dysfunction and the distinctly counterproductive. 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