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Blood samples and resting expired air samples were collected throughout each condition. Statistical analyses were completed using linear mixed models.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>In participants with overweight\/obesity, postprandial glucose, triglycerides (TAG) and metabolic load index (MLI) over time were lower, whereas resting substrate utilisation and resting energy expenditure (REE) were higher, in INT-SIT than SIT (all <jats:italic>p<\/jats:italic>\u2009\u2264\u20090.05). Compared with SIT (0.18 [95% CI 0.13, 0.22] kcal<jats:sup>.<\/jats:sup>min<jats:sup>\u22121<\/jats:sup>), INT-SIT (0.23 [95% CI 0.18, 0.27] kcal<jats:sup>.<\/jats:sup>min<jats:sup>\u22121<\/jats:sup>) increased postprandial REE iAUC in participants with overweight\/obesity (<jats:italic>p<\/jats:italic>\u2009=\u20090.04, <jats:italic>d<\/jats:italic>\u2009=\u20090.51). Postprandial TAG concentrations over time were lower in INT-SIT versus SIT (<jats:italic>p<\/jats:italic>\u2009=\u20090.01, <jats:italic>d<\/jats:italic>\u2009=\u200930) in normal-weight participants, with no differences in any other outcomes for this sample group.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>These findings suggest that interrupting sitting with 5-min bouts of light walking every 30-min acutely attenuates cardiometabolic risk markers among South Asians living with overweight\/obesity, whereas limited effects may be seen in individuals with normal-weight.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00421-023-05345-7","type":"journal-article","created":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T06:01:30Z","timestamp":1699682490000},"page":"1163-1174","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Interrupting sitting acutely attenuates cardiometabolic risk markers in South Asian adults living with overweight and obesity"],"prefix":"10.1007","volume":"124","author":[{"given":"Kamalesh Chandra","family":"Dey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia K.","family":"Zakrzewski-Fruer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsey R.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca L.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3772-630X","authenticated-orcid":false,"given":"Daniel P.","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,11,11]]},"reference":[{"key":"5345_CR1","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.diabres.2010.04.012","volume":"89","author":"A Abdullah","year":"2010","unstructured":"Abdullah A, Peeters A, de Courten M, Stoelwinder J (2010) The magnitude of association between overweight and obesity and the risk of diabetes: a meta-analysis of prospective cohort studies. 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