{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T13:12:49Z","timestamp":1791724369262,"version":"4.3.4"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2024,7,28]],"date-time":"2024-07-28T00:00:00Z","timestamp":1722124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,28]],"date-time":"2024-07-28T00:00:00Z","timestamp":1722124800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Appl Physiol"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p>Sodium bicarbonate (NaHCO<jats:sub>3<\/jats:sub>) ingestion has been found to be ergogenic in high-intensity exercise that ranges from 1 to 10\u00a0min; however, limited studies have investigated high-intensity exercise beyond this duration.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>The present study aimed to determine the effect of NaHCO<jats:sub>3<\/jats:sub> ingested using a carbohydrate hydrogel delivery system on 40\u00a0km time trial (TT) performance in trained male cyclists.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Fourteen trained male cyclists ingested 0.3\u00a0g\u00a0kg<jats:sup>\u22121<\/jats:sup> BM NaHCO<jats:sub>3<\/jats:sub> (Maurten AB, Sweden) to determine individualised peak alkalosis, which established time of ingestion prior to exercise. Participants completed a 40\u00a0km familiarisation TT, and two 40\u00a0km experimental TTs after ingestion of either NaHCO<jats:sub>3<\/jats:sub> or placebo in a randomised, double-blind, crossover design.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>NaHCO<jats:sub>3<\/jats:sub> supplementation improved performance (mean improvement\u2009=\u200954.14\u00a0s\u2009\u00b1\u200918.16\u00a0s; <jats:italic>p<\/jats:italic>\u2009=\u20090.002, <jats:italic>g<\/jats:italic>\u2009=\u20090.22) and increased blood buffering capacity prior to (HCO<jats:sub>3<\/jats:sub><jats:sup>\u2212<\/jats:sup> mean increase\u2009=\u20095.6\u2009\u00b1\u20090.2\u00a0mmol\u00a0L<jats:sup>\u22121<\/jats:sup>, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and throughout exercise (<jats:italic>f<\/jats:italic>\u2009=\u200984.82, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, p\u03b7<jats:sup>2<\/jats:sup>\u2009=\u20090.87) compared to placebo. There were no differences in total gastrointestinal symptoms (GIS) between conditions either pre- (NaHCO<jats:sub>3<\/jats:sub>, 22 AU; Placebo, 44 AU; <jats:italic>p<\/jats:italic>\u2009=\u20090.088, <jats:italic>r<\/jats:italic>\u2009=\u20090.46) or post-exercise (NaHCO<jats:sub>3<\/jats:sub>, 76 AU; Placebo, 63 AU; <jats:italic>p<\/jats:italic>\u2009=\u20090.606, <jats:italic>r<\/jats:italic>\u2009=\u20090.14).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The present study suggests that ingesting NaHCO<jats:sub>3<\/jats:sub> mini-tablets in a carbohydrate hydrogel can enhance 40\u00a0km TT performance in trained male cyclists, with minimal GIS. This ingestion strategy could therefore be considered by cyclists looking for a performance enhancing ergogenic aid.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00421-024-05567-3","type":"journal-article","created":{"date-parts":[[2024,7,28]],"date-time":"2024-07-28T09:01:43Z","timestamp":1722157303000},"page":"3671-3682","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The effect of sodium bicarbonate mini-tablets ingested in a carbohydrate hydrogel system on 40\u00a0km cycling time trial performance and metabolism in trained male cyclists"],"prefix":"10.1007","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-8889-6420","authenticated-orcid":false,"given":"Eli Spencer","family":"Shannon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0995-3877","authenticated-orcid":false,"given":"Amanda","family":"Regnier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0413-878X","authenticated-orcid":false,"given":"Ben","family":"Dobson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7286-5108","authenticated-orcid":false,"given":"Xiaolin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0910-2225","authenticated-orcid":false,"given":"S. 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