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We examined whether muscle quality indices were significant predictors of the whole-body reaction time (WBRT) in healthy female and male adults aged 20\u201391\u00a0years.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Data from 5164 adults (2869 women and 2295 men; mean age\u2009\u00b1\u2009standard deviation, 60.9\u2009\u00b1\u200915.6\u00a0years) were analyzed. Height and weight were measured, and body mass index was calculated. ALM was estimated using a previously validated 8-electrode multi-frequency BIA. PhA was measured at 50\u00a0kHz using a BIA device. Knee extension strength (KES), leg extension power (LEP), and flexibility were examined. The ALM to weight (ALM\/weight), KES to ALM (KES\/ALM), and LEP to KES (LEP\/KES) ratios were calculated. In the WBRT test, participants were asked to stand on a force plate and jump upright as quickly as possible in response to a light stimulus. The WBRT was divided into the response initiation and motion execution phases.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>ALM\/weight, KES\/ALM, LEP\/KES, PhA, and flexibility were significant independent predictors of WBRT and the time of the motion execution phase (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). However, PhA was not a significant predictor of the time of response initiation phase.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Muscle quantity (ALM\/weight), muscle quality (KES\/ALM and LEP\/KES), PhA, and flexibility are determinants of WBRT test performance, particularly in the motion execution phase.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00421-024-05591-3","type":"journal-article","created":{"date-parts":[[2024,9,8]],"date-time":"2024-09-08T11:01:48Z","timestamp":1725793308000},"page":"167-173","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effects of muscle quantity, muscle quality, and phase angle on whole-body reaction time in 5164 adults aged 20\u201391\u00a0years"],"prefix":"10.1007","volume":"125","author":[{"given":"Wataru","family":"Fukuda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Yoshihisa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4284-6317","authenticated-orcid":false,"given":"Yosuke","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,8]]},"reference":[{"issue":"1","key":"5591_CR1","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1002\/jcsm.12860","volume":"13","author":"Y Akamatsu","year":"2022","unstructured":"Akamatsu Y, Kusakabe T, Arai H, Yamamoto Y, Nakao K, Ikeue K, Ishihara Y, Tagami T, Yasoda A, Ishii K, Satoh-Asahara N (2022) Phase angle from bioelectrical impedance analysis is a useful indicator of muscle quality. 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