{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T19:00:37Z","timestamp":1787857237575,"version":"build-2784847793"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:00:00Z","timestamp":1733788800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:00:00Z","timestamp":1733788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Appl Physiol"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1007\/s00421-024-05684-z","type":"journal-article","created":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T03:51:32Z","timestamp":1733802692000},"page":"1311-1322","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The first case of a competitive basketball player affected by carnitine palmitoyl transferase II deficiency presenting an undescribed compound heterozygous genetic mutation"],"prefix":"10.1007","volume":"125","author":[{"given":"Oscar","family":"Crisafulli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venere","family":"Quintiero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Grattarola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Bottoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Giovanetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Negro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuela","family":"Lavaselli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0683-5565","authenticated-orcid":false,"given":"Giuseppe","family":"D\u2019Antona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,10]]},"reference":[{"issue":"1","key":"5684_CR1","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1097\/00005768-200201000-00015","volume":"34","author":"J Achten","year":"2002","unstructured":"Achten J, Gleeson M, Jeukendrup AE (2002) Determination of the exercise intensity that elicits maximal fat oxidation. Med Sci Sports Exerc 34(1):92\u201397. https:\/\/doi.org\/10.1097\/00005768-200201000-00015","journal-title":"Med Sci Sports Exerc"},{"issue":"6","key":"5684_CR2","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1016\/s0026-0495(03)00068-4","volume":"52","author":"J Achten","year":"2003","unstructured":"Achten J, Venables MC, Jeukendrup AE (2003) Fat oxidation rates are higher during running compared with cycling over a wide range of intensities. Metabolism 52(6):747\u2013752. https:\/\/doi.org\/10.1016\/s0026-0495(03)00068-4","journal-title":"Metabolism"},{"key":"5684_CR3","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201600772","author":"S Andres","year":"2017","unstructured":"Andres S, Ziegenhagen R, Trefflich I, Pevny S, Schultrich K, Braun H, Sch\u00e4nzer W, Hirsch-Ernst KI, Sch\u00e4fer B, Lampen A (2017) Creatine and creatine forms intended for sports nutrition. Mol Nutr Food Res. https:\/\/doi.org\/10.1002\/mnfr.201600772","journal-title":"Mol Nutr Food Res"},{"key":"5684_CR4","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.937084","volume":"23","author":"R Arbab","year":"2022","unstructured":"Arbab R, Erb C, Joy J, Zainah H, Samarneh MM (2022) Physiologic response to exercise or rhabdomyolysis? Creatine phosphokinase elevation in 16 asymptomatic firefighters. Am J Case Rep 23:e937084. https:\/\/doi.org\/10.12659\/AJCR.937084","journal-title":"Am J Case Rep"},{"issue":"2","key":"5684_CR5","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1097\/JSM.0000000000001082","volume":"33","author":"HC B\u00e4cker","year":"2023","unstructured":"B\u00e4cker HC, Richards JT, Kienzle A, Cunningham J, Braun KF (2023) Exertional rhabdomyolysis in athletes: systematic review and current perspectives. Clin J Sport Med 33(2):187\u2013194. https:\/\/doi.org\/10.1097\/JSM.0000000000001082","journal-title":"Clin J Sport Med"},{"issue":"6","key":"5684_CR6","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.medcli.2021.09.025","volume":"158","author":"R Baeza-Trinidad","year":"2022","unstructured":"Baeza-Trinidad R (2022) Rhabdomyolysis: a syndrome to be considered. Med Clin (Barc) 158(6):277\u2013283. https:\/\/doi.org\/10.1016\/j.medcli.2021.09.025","journal-title":"Med Clin (Barc)"},{"issue":"11","key":"5684_CR7","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1136\/bjsm.2007.043786","volume":"42","author":"A Bessa","year":"2008","unstructured":"Bessa A, Nissenbaum M, Monteiro A, Gandra PG, Nunes LS, Bassini-Cameron A, Werneck-de-Castro JP, de Macedo DV, Cameron LC (2008) High-intensity ultraendurance promotes early release of muscle injury markers. Br J Sports Med 42(11):889\u2013893. https:\/\/doi.org\/10.1136\/bjsm.2007.043786","journal-title":"Br J Sports Med"},{"issue":"2","key":"5684_CR8","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1097\/00002480-200103000-00205","volume":"47","author":"S Biasioli","year":"2001","unstructured":"Biasioli S, Foroni R, Cavallini L, Petrosino L (2001) Long term analysis changes of 35 biochemicals and bioelectrical parameters in a dialytic population. ASAIO J 47(2):152","journal-title":"ASAIO J"},{"issue":"5\u20136","key":"5684_CR9","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1016\/j.mam.2004.06.004","volume":"25","author":"JP Bonnefont","year":"2004","unstructured":"Bonnefont JP, Djouadi F, Prip-Buus C, Gobin S, Munnich A, Bastin J (2004) Carnitine palmitoyltransferases 1 and 2: biochemical, molecular and medical aspects. Mol Aspects Med 25(5\u20136):495\u2013520. https:\/\/doi.org\/10.1016\/j.mam.2004.06.004","journal-title":"Mol Aspects Med"},{"issue":"2","key":"5684_CR10","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1002\/cphy.c110025","volume":"2","author":"FW Booth","year":"2012","unstructured":"Booth FW, Roberts CK, Laye MJ (2012) Lack of exercise is a major cause of chronic diseases. Compr Physiol 2(2):1143\u20131211. https:\/\/doi.org\/10.1002\/cphy.c110025","journal-title":"Compr Physiol"},{"issue":"1","key":"5684_CR11","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1080\/00913847.2016.1102033","volume":"44","author":"J Calleja-Gonz\u00e1lez","year":"2016","unstructured":"Calleja-Gonz\u00e1lez J, Terrados N, Mielgo-Ayuso J, Delextrat A, Jukic I, Vaquera A, Torres L, Schelling X, Stojanovic M, Ostojic SM (2016) Evidence-based post-exercise recovery strategies in basketball. Phys Sportsmed 44(1):74\u201378. https:\/\/doi.org\/10.1080\/00913847.2016.1102033","journal-title":"Phys Sportsmed"},{"issue":"3","key":"5684_CR12","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1249\/mss.0000000000001472","volume":"50","author":"B Cheval","year":"2018","unstructured":"Cheval B, Sieber S, Guessous I, Orsholits D, Courvoisier DS, Kliegel M, Stringhini S, Swinnen SP, Burton-Jeangros C, Cullati S, Boisgontier MP (2018) Effect of early- and adult-life socioeconomic circumstances on physical inactivity. Med Sci Sports Exerc 50(3):476\u2013485. https:\/\/doi.org\/10.1249\/mss.0000000000001472","journal-title":"Med Sci Sports Exerc"},{"issue":"7","key":"5684_CR13","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1111\/1756-185x.14104","volume":"24","author":"I CoskunBenlidayi","year":"2021","unstructured":"CoskunBenlidayi I, Gupta L (2021) The pathophysiological effects of exercise in the management of idiopathic inflammatory myopathies: a scoping review. Int J Rheum Dis 24(7):896\u2013903. https:\/\/doi.org\/10.1111\/1756-185x.14104","journal-title":"Int J Rheum Dis"},{"key":"5684_CR14","doi-asserted-by":"publisher","first-page":"1035255","DOI":"10.3389\/fphys.2022.1035255","volume":"13","author":"O Crisafulli","year":"2022","unstructured":"Crisafulli O, Baroscelli M, Grattarola L, Tansini G, Zampella C, D\u2019Antona G (2022) Case report: Personalized adapted motor activity in a COVID-19 patient complicated by critical illness polyneuropathy and myopathy. Front Physiol 13:1035255. https:\/\/doi.org\/10.3389\/fphys.2022.1035255","journal-title":"Front Physiol"},{"key":"5684_CR15","doi-asserted-by":"publisher","first-page":"1404657","DOI":"10.3389\/fphys.2024.1404657","volume":"15","author":"O Crisafulli","year":"2024","unstructured":"Crisafulli O, Lacetera J, Bottoni G, Berardinelli A, Grattarola L, Veltroni M, Acquadro S, Negro M, Lavaselli E, D\u2019Antona G (2024) Case report: A creatine kinase-borg scale values-based approach to tailor physical training in a central core myopathy patient. Front Physiol 15:1404657. https:\/\/doi.org\/10.3389\/fphys.2024.1404657","journal-title":"Front Physiol"},{"key":"5684_CR16","doi-asserted-by":"publisher","first-page":"103","DOI":"10.2478\/hukin-2013-0073","volume":"39","author":"M Czuba","year":"2013","unstructured":"Czuba M, Zaj\u0105c A, Maszczyk A, Roczniok R, Poprz\u0119cki S, Garbaciak W, Zaj\u0105c T (2013) The effects of high intensity interval training in normobaric hypoxia on aerobic capacity in basketball players. J Hum Kinet 39:103\u2013114. https:\/\/doi.org\/10.2478\/hukin-2013-0073","journal-title":"J Hum Kinet"},{"issue":"7","key":"5684_CR17","doi-asserted-by":"publisher","first-page":"1882","DOI":"10.1519\/jsc.0000000000002570","volume":"32","author":"A Delextrat","year":"2018","unstructured":"Delextrat A, Gruet M, Bieuzen F (2018) Effects of small-sided games and high-intensity interval training on aerobic and repeated sprint performance and peripheral muscle oxygenation changes in Elite junior basketball players. J Strength Cond Res 32(7):1882\u20131891. https:\/\/doi.org\/10.1519\/jsc.0000000000002570","journal-title":"J Strength Cond Res"},{"issue":"1","key":"5684_CR18","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1001\/archneur.62.1.37","volume":"62","author":"M Deschauer","year":"2005","unstructured":"Deschauer M, Wieser T, Zierz S (2005) Muscle carnitine palmitoyltransferase II deficiency: clinical and molecular genetic features and diagnostic aspects. Arch Neurol 62(1):37\u201341. https:\/\/doi.org\/10.1001\/archneur.62.1.37","journal-title":"Arch Neurol"},{"key":"5684_CR19","unstructured":"DRI Dietary Reference Intakes (2000) Applications in Dietary Assessment. National Academies Press (US), Washington (DC)"},{"issue":"3","key":"5684_CR20","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1111\/j.1399-0004.2011.01786.x","volume":"82","author":"M Fanin","year":"2012","unstructured":"Fanin M, Anichini A, Cassandrini D, Fiorillo C, Scapolan S, Minetti C, Cassanello M, Donati MA, Siciliano G, D\u2019Amico A, Lilliu F, Bruno C, Angelini C (2012) Allelic and phenotypic heterogeneity in 49 Italian patients with the muscle form of CPT-II deficiency. Clin Genet 82(3):232\u2013239. https:\/\/doi.org\/10.1111\/j.1399-0004.2011.01786.x","journal-title":"Clin Genet"},{"key":"5684_CR21","doi-asserted-by":"publisher","first-page":"181","DOI":"10.2478\/hukin-2020-0048","volume":"77","author":"B Figueira","year":"2021","unstructured":"Figueira B, Gon\u00e7alves B, Abade E, Paulauskas R, Masiulis N, Kamarauskas P, Sampaio J (2021) Repeated Sprint Ability in Elite basketball players: the effects of 10 \u00d7 30 m vs. 20 \u00d7 15 m exercise protocols on physiological variables and sprint performance. J Hum Kinet 77:181\u2013189. https:\/\/doi.org\/10.2478\/hukin-2020-0048","journal-title":"J Hum Kinet"},{"issue":"2","key":"5684_CR22","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1152\/jappl.1983.55.2.628","volume":"55","author":"KN Frayn","year":"1983","unstructured":"Frayn KN (1983) Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol Respir Environ Exerc Physiol 55(2):628\u2013634. https:\/\/doi.org\/10.1152\/jappl.1983.55.2.628","journal-title":"J Appl Physiol Respir Environ Exerc Physiol"},{"issue":"3","key":"5684_CR23","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/s12020-018-1580-x","volume":"61","author":"D Giugliano","year":"2018","unstructured":"Giugliano D, Maiorino MI, Bellastella G, Esposito K (2018) More sugar? No, thank you! The elusive nature of low carbohydrate diets. Endocrine 61(3):383\u2013387. https:\/\/doi.org\/10.1007\/s12020-018-1580-x","journal-title":"Endocrine"},{"key":"5684_CR24","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1111\/j.1753-4887.1964.tb04848.x","volume":"22","author":"N Guthrie","year":"1964","unstructured":"Guthrie N, Runyan JW, Clark G, Marvin O (1964) Carbohydrate intake and respiratory quotient. Nutr Rev 22:105\u2013107. https:\/\/doi.org\/10.1111\/j.1753-4887.1964.tb04848.x","journal-title":"Nutr Rev"},{"issue":"8","key":"5684_CR25","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a029744","volume":"8","author":"M Hargreaves","year":"2018","unstructured":"Hargreaves M, Spriet LL (2018) Exercise metabolism: fuels for the fire. Cold Spring Harb Perspect Med 8(8):a029744. https:\/\/doi.org\/10.1101\/cshperspect.a029744","journal-title":"Cold Spring Harb Perspect Med"},{"issue":"4","key":"5684_CR26","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/j.ymgme.2006.08.004","volume":"89","author":"PJ Isackson","year":"2006","unstructured":"Isackson PJ, Bennett MJ, Vladutiu GD (2006) Identification of 16 new disease-causing mutations in the CPT2 gene resulting in carnitine palmitoyltransferase II deficiency. Mol Genet Metab 89(4):323\u2013331. https:\/\/doi.org\/10.1016\/j.ymgme.2006.08.004","journal-title":"Mol Genet Metab"},{"issue":"1","key":"5684_CR27","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1111\/j.1467-789x.2011.00931.x","volume":"13","author":"I Ismail","year":"2012","unstructured":"Ismail I, Keating SE, Baker MK, Johnson NA (2012) A systematic review and meta-analysis of the effect of aerobic vs. resistance exercise training on visceral fat. Obes Rev 13(1):68\u201391. https:\/\/doi.org\/10.1111\/j.1467-789x.2011.00931.x","journal-title":"Obes Rev"},{"issue":"3","key":"5684_CR28","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1093\/ajcn\/67.3.397","volume":"67","author":"AE Jeukendrup","year":"1998","unstructured":"Jeukendrup AE, Thielen JJ, Wagenmakers AJ, Brouns F, Saris WH (1998) Effect of medium-chain triacylglycerol and carbohydrate ingestion during exercise on substrate utilization and subsequent cycling performance. Am J Clin Nutr 67(3):397\u2013404. https:\/\/doi.org\/10.1093\/ajcn\/67.3.397","journal-title":"Am J Clin Nutr"},{"issue":"8","key":"5684_CR29","doi-asserted-by":"publisher","first-page":"1784","DOI":"10.3390\/molecules25081784","volume":"25","author":"PR Joshi","year":"2020","unstructured":"Joshi PR, Zierz S (2020) Muscle carnitine palmitoyltransferase II (CPT II) deficiency: a conceptual approach. Molecules 25(8):1784. https:\/\/doi.org\/10.3390\/molecules25081784","journal-title":"Molecules"},{"issue":"1\u20132","key":"5684_CR30","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.jns.2013.12.026","volume":"338","author":"PR Joshi","year":"2014","unstructured":"Joshi PR, Deschauer M, Zierz S (2014) Carnitine palmitoyltransferase II (CPT II) deficiency: genotype-phenotype analysis of 50 patients. J Neurol Sci 338(1\u20132):107\u2013111. https:\/\/doi.org\/10.1016\/j.jns.2013.12.026","journal-title":"J Neurol Sci"},{"issue":"3","key":"5684_CR31","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1002\/jimd.12480","volume":"45","author":"A Karunanidhi","year":"2022","unstructured":"Karunanidhi A, Van\u2019t Land C, Rajasundaram D, Grings M, Vockley J, Mohsen AW (2022) Medium branched chain fatty acids improve the profile of tricarboxylic acid cycle intermediates in mitochondrial fatty acid \u03b2-oxidation deficient cells: a comparative study. J Inherit Metab Dis 45(3):541\u2013556. https:\/\/doi.org\/10.1002\/jimd.12480","journal-title":"J Inherit Metab Dis"},{"issue":"1","key":"5684_CR32","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s12970-018-0242-y","volume":"15","author":"CM Kerksick","year":"2018","unstructured":"Kerksick CM, Wilborn CD, Roberts MD, Smith-Ryan A, Kleiner SM, J\u00e4ger R, Collins R, Cooke M, Davis JN, Galvan E, Greenwood M, Lowery LM, Wildman R, Antonio J, Kreider RB (2018) ISSN exercise & sports nutrition review update: research & recommendations. J Int Soc Sports Nutr 15(1):38. https:\/\/doi.org\/10.1186\/s12970-018-0242-y","journal-title":"J Int Soc Sports Nutr"},{"issue":"1","key":"5684_CR33","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.jsams.2007.10.004","volume":"12","author":"FL Lazarim","year":"2009","unstructured":"Lazarim FL, Antunes-Neto JM, da Silva FO, Nunes LA, Bassini-Cameron A, Cameron LC, Alves AA, Brenzikofer R, de Macedo DV (2009) The upper values of plasma creatine kinase of professional soccer players during the Brazilian National Championship. J Sci Med Sport 12(1):85\u201390. https:\/\/doi.org\/10.1016\/j.jsams.2007.10.004","journal-title":"J Sci Med Sport"},{"issue":"21","key":"5684_CR34","doi-asserted-by":"publisher","first-page":"11323","DOI":"10.3390\/ijerph182111323","volume":"18","author":"M Lecina","year":"2021","unstructured":"Lecina M, L\u00f3pez I, Castellar C, Pradas F (2021) Extreme ultra-trail race induces muscular damage, risk for acute kidney injury and hyponatremia: a case report. Int J Environ Res Public Health 18(21):11323. https:\/\/doi.org\/10.3390\/ijerph182111323","journal-title":"Int J Environ Res Public Health"},{"issue":"11","key":"5684_CR35","first-page":"22","volume":"97","author":"G Lee","year":"2014","unstructured":"Lee G (2014) Exercise-induced rhabdomyolysis. R I Med J (2013) 97(11):22\u201324","journal-title":"R I Med J (2013)"},{"issue":"10","key":"5684_CR36","doi-asserted-by":"publisher","first-page":"2920","DOI":"10.1519\/jsc.0000000000002122","volume":"31","author":"EC Lee","year":"2017","unstructured":"Lee EC, Fragala MS, Kavouras SA, Queen RM, Pryor JL, Casa DJ (2017) Biomarkers in sports and exercise: tracking health, performance, and recovery in athletes. J Strength Cond Res 31(10):2920\u20132937. https:\/\/doi.org\/10.1519\/jsc.0000000000002122","journal-title":"J Strength Cond Res"},{"issue":"1\u20132","key":"5684_CR37","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.jns.2014.02.011","volume":"339","author":"D Lehmann","year":"2014","unstructured":"Lehmann D, Zierz S (2014) Normal protein content but abnormally inhibited enzyme activity in muscle carnitine palmitoyltransferase II deficiency. J Neurol Sci 339(1\u20132):183\u2013188. https:\/\/doi.org\/10.1016\/j.jns.2014.02.011","journal-title":"J Neurol Sci"},{"issue":"10","key":"5684_CR38","doi-asserted-by":"publisher","first-page":"2098","DOI":"10.1249\/mss.0000000000002033","volume":"51","author":"JJ Matthews","year":"2019","unstructured":"Matthews JJ, Artioli GG, Turner MD, Sale C (2019) The physiological roles of carnosine and \u03b2-alanine in exercising human skeletal muscle. Med Sci Sports Exerc 51(10):2098\u20132108. https:\/\/doi.org\/10.1249\/mss.0000000000002033","journal-title":"Med Sci Sports Exerc"},{"issue":"10","key":"5684_CR39","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2021.102897","volume":"20","author":"RG Misse","year":"2021","unstructured":"Misse RG, Borges IBP, Dos Santos AM, Gupta L, Shinjo SK (2021) Effect of exercise training on fatigue and pain in patients with systemic autoimmune myopathies: a systematic review. Autoimmun Rev 20(10):102897. https:\/\/doi.org\/10.1016\/j.autrev.2021.102897","journal-title":"Autoimmun Rev"},{"key":"5684_CR40","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/bs.pmbts.2015.07.020","volume":"135","author":"JD Mul","year":"2015","unstructured":"Mul JD, Stanford KI, Hirshman MF, Goodyear LJ (2015) Exercise and regulation of carbohydrate metabolism. Prog Mol Biol Transl Sci 135:17\u201337. https:\/\/doi.org\/10.1016\/bs.pmbts.2015.07.020","journal-title":"Prog Mol Biol Transl Sci"},{"key":"5684_CR41","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.704290","volume":"12","author":"M Negro","year":"2021","unstructured":"Negro M, Cerullo G, Parimbelli M, Ravazzani A, Feletti F, Berardinelli A, Cena H, D\u2019Antona G (2021) Exercise, nutrition, and supplements in the muscle carnitine palmitoyl-transferase II deficiency: new theoretical bases for potential applications. Front Physiol 12:704290. https:\/\/doi.org\/10.3389\/fphys.2021.704290","journal-title":"Front Physiol"},{"key":"5684_CR42","doi-asserted-by":"publisher","first-page":"1150265","DOI":"10.3389\/fphys.2023.1150265","volume":"14","author":"TD Noakes","year":"2023","unstructured":"Noakes TD, Prins PJ, Volek JS, D\u2019Agostino DP, Koutnik AP (2023) Low carbohydrate high fat ketogenic diets on the exercise crossover point and glucose homeostasis. Front Physiol 14:1150265. https:\/\/doi.org\/10.3389\/fphys.2023.1150265","journal-title":"Front Physiol"},{"issue":"4","key":"5684_CR43","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1212\/01.wnl.0000078195.05396.20","volume":"61","author":"MC \u00d8rngreen","year":"2003","unstructured":"\u00d8rngreen MC, Ejstrup R, Vissing J (2003) Effect of diet on exercise tolerance in carnitine palmitoyltransferase II deficiency. Neurology 61(4):559\u2013561. https:\/\/doi.org\/10.1212\/01.wnl.0000078195.05396.20","journal-title":"Neurology"},{"issue":"1","key":"5684_CR44","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1002\/ana.20320","volume":"57","author":"MC \u00d8rngreen","year":"2005","unstructured":"\u00d8rngreen MC, Dun\u00f8 M, Ejstrup R, Christensen E, Schwartz M, Sacchetti M, Vissing J (2005) Fuel utilization in subjects with carnitine palmitoyltransferase 2 gene mutations. Ann Neurol 57(1):60\u201366. https:\/\/doi.org\/10.1002\/ana.20320","journal-title":"Ann Neurol"},{"key":"5684_CR45","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.637406","volume":"12","author":"M Parimbelli","year":"2021","unstructured":"Parimbelli M, Pezzotti E, Negro M, Calanni L, Allemano S, Bernardi M, Berardinelli A, D\u2019Antona G (2021) Nutrition and exercise in a case of carnitine palmitoyl-transferase II deficiency. Front Physiol 12:637406. https:\/\/doi.org\/10.3389\/fphys.2021.637406","journal-title":"Front Physiol"},{"issue":"1","key":"5684_CR46","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1249\/mss.0000000000001084","volume":"49","author":"RK Randell","year":"2017","unstructured":"Randell RK, Rollo I, Roberts TJ, Dalrymple KJ, Jeukendrup AE, Carter JM (2017) Maximal fat oxidation rates in an athletic population. Med Sci Sports Exerc 49(1):133\u2013140. https:\/\/doi.org\/10.1249\/mss.0000000000001084","journal-title":"Med Sci Sports Exerc"},{"issue":"1","key":"5684_CR47","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1159\/000194056","volume":"38","author":"U Reinhard","year":"1979","unstructured":"Reinhard U, M\u00fcller PH, Schm\u00fclling RM (1979) Determination of anaerobic threshold by the ventilation equivalent in normal individuals. Respiration 38(1):36\u201342. https:\/\/doi.org\/10.1159\/000194056","journal-title":"Respiration"},{"issue":"10","key":"5684_CR48","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1089\/omi.2011.0010","volume":"15","author":"NM Resende","year":"2011","unstructured":"Resende NM, de Magalh\u00e3esNeto AM, Bachini F, de Castro LE, Bassini A, Cameron LC (2011) Metabolic changes during a field experiment in a world-class windsurfing athlete: a trial with multivariate analyses. OMICS 15(10):695\u2013704. https:\/\/doi.org\/10.1089\/omi.2011.0010","journal-title":"OMICS"},{"issue":"4","key":"5684_CR49","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1212\/01.wnl.0000318283.42961.e9","volume":"71","author":"CR Roe","year":"2008","unstructured":"Roe CR, Yang BZ, Brunengraber H, Roe DS, Wallace M, Garritson BK (2008) Carnitine palmitoyltransferase II deficiency: successful anaplerotic diet therapy. Neurology 71(4):260\u2013264. https:\/\/doi.org\/10.1212\/01.wnl.0000318283.42961.e9","journal-title":"Neurology"},{"issue":"9","key":"5684_CR50","doi-asserted-by":"publisher","first-page":"e419","DOI":"10.1016\/s2468-2667(18)30135-x","volume":"3","author":"SB Seidelmann","year":"2018","unstructured":"Seidelmann SB, Claggett B, Cheng S, Henglin M, Shah A, Steffen LM, Folsom AR, Rimm EB, Willett WC, Solomon SD (2018) Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis. Lancet Public Health 3(9):e419\u2013e428. https:\/\/doi.org\/10.1016\/s2468-2667(18)30135-x","journal-title":"Lancet Public Health"},{"issue":"1","key":"5684_CR51","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1152\/jappl.1983.54.1.13","volume":"54","author":"J Simon","year":"1983","unstructured":"Simon J, Young JL, Gutin B, Blood DK, Case RB (1983) Lactate accumulation relative to the anaerobic and respiratory compensation thresholds. J Appl Physiol Respir Environ Exerc Physiol 54(1):13\u201317. https:\/\/doi.org\/10.1152\/jappl.1983.54.1.13","journal-title":"J Appl Physiol Respir Environ Exerc Physiol"},{"issue":"8","key":"5684_CR52","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1093\/qjmed\/hcab077","volume":"114","author":"A Tan","year":"2021","unstructured":"Tan A, Stepien KM, Narayana STK (2021) Carnitine palmitoyltransferase II deficiency and post-COVID vaccination rhabdomyolysis. QJM 114(8):596\u2013597. https:\/\/doi.org\/10.1093\/qjmed\/hcab077","journal-title":"QJM"},{"issue":"4","key":"5684_CR53","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1123\/ijsnem.10.4.452","volume":"10","author":"MA Tarnopolsky","year":"2000","unstructured":"Tarnopolsky MA, MacLennan DP (2000) Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females. Int J Sport Nutr Exerc Metab 10(4):452\u2013463. https:\/\/doi.org\/10.1123\/ijsnem.10.4.452","journal-title":"Int J Sport Nutr Exerc Metab"},{"issue":"1","key":"5684_CR54","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1152\/japplphysiol.00662.2003","volume":"98","author":"MC Venables","year":"2005","unstructured":"Venables MC, Achten J, Jeukendrup AE (2005) Determinants of fat oxidation during exercise in healthy men and women: a cross-sectional study. J Appl Physiol 98(1):160\u2013167. https:\/\/doi.org\/10.1152\/japplphysiol.00662.2003","journal-title":"J Appl Physiol"},{"issue":"1","key":"5684_CR55","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/jimd.12313","volume":"44","author":"J Vockley","year":"2021","unstructured":"Vockley J, Burton B, Berry G, Longo N, Phillips J, Sanchez-Valle A, Chapman K, Tanpaiboon P, Grunewald S, Murphy E, Lu X, Cataldo J (2021) Effects of triheptanoin (UX007) in patients with long-chain fatty acid oxidation disorders: results from an open-label, long-term extension study. J Inherit Metab Dis 44(1):253\u2013263. https:\/\/doi.org\/10.1002\/jimd.12313","journal-title":"J Inherit Metab Dis"},{"key":"5684_CR56","doi-asserted-by":"publisher","first-page":"1190109","DOI":"10.3389\/fphys.2023.1190109","volume":"14","author":"D Wang","year":"2023","unstructured":"Wang D, Zhang P, Li J (2023) Crossover point and maximal fat oxidation training effects on blood lipid metabolism in young overweight women: a pilot study. Front Physiol 14:1190109. https:\/\/doi.org\/10.3389\/fphys.2023.1190109","journal-title":"Front Physiol"},{"issue":"1","key":"5684_CR57","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1054\/clnu.2000.0362","volume":"20","author":"LC Ward","year":"2001","unstructured":"Ward LC, Heitmann BL (2001) Assessment of body composition by bioelectrical impedance analysis without the need for measurement of height. Clin Nutr 20(1):21\u201326. https:\/\/doi.org\/10.1054\/clnu.2000.0362","journal-title":"Clin Nutr"},{"issue":"8","key":"5684_CR58","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1212\/01.wnl.0000055901.58642.48","volume":"60","author":"T Wieser","year":"2003","unstructured":"Wieser T, Deschauer M, Olek K, Hermann T, Zierz S (2003) Carnitine palmitoyltransferase II deficiency: molecular and biochemical analysis of 32 patients. Neurology 60(8):1351\u20131353. https:\/\/doi.org\/10.1212\/01.wnl.0000055901.58642.48","journal-title":"Neurology"}],"container-title":["European Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00421-024-05684-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00421-024-05684-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00421-024-05684-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T11:37:01Z","timestamp":1746531421000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00421-024-05684-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,10]]},"references-count":58,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["5684"],"URL":"https:\/\/doi.org\/10.1007\/s00421-024-05684-z","relation":{},"ISSN":["1439-6319","1439-6327"],"issn-type":[{"value":"1439-6319","type":"print"},{"value":"1439-6327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,10]]},"assertion":[{"value":"2 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None of the authors declare has any conflict of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}