{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T21:21:59Z","timestamp":1788211319223,"version":"build-2803163510"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Appl Physiol"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s00421-025-06019-2","type":"journal-article","created":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T15:17:54Z","timestamp":1762269474000},"page":"2051-2061","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Physiological responses to cardiopulmonary and field exercise tests in primary ciliary dyskinesia compared with healthy peers"],"prefix":"10.1007","volume":"126","clinical-trial-number":[{"clinical-trial-number":"nct05712798","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2474-8000","authenticated-orcid":false,"given":"Aslihan","family":"Cakmak-Onal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5650-8992","authenticated-orcid":false,"given":"Elif","family":"Kocaaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7815-4072","authenticated-orcid":false,"given":"Hazal","family":"Sonbahar-Ulu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5215-5125","authenticated-orcid":false,"given":"Ebru","family":"Calik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0218-140X","authenticated-orcid":false,"given":"Naciye","family":"Vardar-Yagli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5323-1943","authenticated-orcid":false,"given":"Melda","family":"Saglam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9818-8782","authenticated-orcid":false,"given":"Birce","family":"Sunman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1405-8401","authenticated-orcid":false,"given":"Nagehan","family":"Emiralioglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1587-5216","authenticated-orcid":false,"given":"Ugur","family":"Ozcelik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8151-0664","authenticated-orcid":false,"given":"Deniz","family":"Inal-Ince","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,4]]},"reference":[{"issue":"10","key":"6019_CR1","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1136\/hrt.2007.121558","volume":"93","author":"K Albouaini","year":"2007","unstructured":"Albouaini K, Egred M, Alahmar A, Wright DJ (2007) Cardiopulmonary exercise testing and its application. Heart 93(10):1285\u20131292. https:\/\/doi.org\/10.1136\/hrt.2007.121558","journal-title":"Heart"},{"issue":"2","key":"6019_CR2","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1164\/rccm.167.2.211","volume":"167","author":"American Thoracic Society; American College of Chest Physicians","year":"2003","unstructured":"American Thoracic Society; American College of Chest Physicians (2003) ATS\/ACCP statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med 167(2):211\u2013277. https:\/\/doi.org\/10.1164\/rccm.167.2.211","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"6019_CR3","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1002\/ppul.20942","volume":"44","author":"H Ben Saad","year":"2009","unstructured":"Ben Saad H, Prefaut C, Missaoui R, Mohamed IH, Tabka Z, Hayot M (2009) Reference equation for 6-min walk distance in healthy North African children 6\u201316 years old. Pediatr Pulmonol 44(4):316\u2013324. https:\/\/doi.org\/10.1002\/ppul.20942","journal-title":"Pediatr Pulmonol"},{"issue":"6","key":"6019_CR4","doi-asserted-by":"publisher","first-page":"1802","DOI":"10.1016\/j.athoracsur.2012.03.022","volume":"93","author":"A Brunelli","year":"2012","unstructured":"Brunelli A, Belardinelli R, Pompili C, Xiume F, Refai M, Salati M, Sabbatini A (2012) Minute ventilation-to-carbon dioxide output (VE\/VCO2) slope is the strongest predictor of respiratory complications and death after pulmonary resection. Ann Thorac Surg 93(6):1802\u20131806. https:\/\/doi.org\/10.1016\/j.athoracsur.2012.03.022","journal-title":"Ann Thorac Surg"},{"issue":"18","key":"6019_CR5","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1056\/Nejm199910283411804","volume":"341","author":"CR Cole","year":"1999","unstructured":"Cole CR, Blackstone EH, Pashkow FJ, Snader CE, Lauer MS (1999) Heart-rate recovery immediately after exercise as a predictor of mortality. N Engl J Med 341(18):1351\u20131357. https:\/\/doi.org\/10.1056\/Nejm199910283411804","journal-title":"N Engl J Med"},{"issue":"10","key":"6019_CR6","doi-asserted-by":"publisher","first-page":"1726","DOI":"10.1513\/AnnalsATS.201603-198OC","volume":"13","author":"SD Dell","year":"2016","unstructured":"Dell SD, Leigh MW, Lucas JS, Ferkol TW, Knowles MR, Alpern A, Behan L, Morris AM, Hogg C, DunnGalvin A, Quittner AL (2016) Primary ciliary dyskinesia: first health-related quality-of-life measures for pediatric patients. Ann Am Thorac Soc 13(10):1726\u20131735. https:\/\/doi.org\/10.1513\/AnnalsATS.201603-198OC","journal-title":"Ann Am Thorac Soc"},{"issue":"2","key":"6019_CR7","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1002\/ppul.10217","volume":"35","author":"R Dom\u00e8nech-Clar","year":"2003","unstructured":"Dom\u00e8nech-Clar R, L\u00f3pez-Andreu JA, Compte-Torrero L, De Diego-Dami\u00e1 A, Maci\u00e1n-Gisbert V, Perpi\u00f1\u00e1-Tordera M, Roqu\u00e9s-Serradilla JM (2003) Maximal static respiratory pressures in children and adolescents. Pediatr Pulmonol 35(2):126\u2013132. https:\/\/doi.org\/10.1002\/ppul.10217","journal-title":"Pediatr Pulmonol"},{"issue":"1","key":"6019_CR8","doi-asserted-by":"publisher","first-page":"19","DOI":"10.5152\/TurkThoracJ.2017.16049","volume":"18","author":"N Emiralioglu","year":"2017","unstructured":"Emiralioglu N, Karadag B, Ozcelik HU (2017) Quality of life questionnaire for Turkish patients with primary ciliary dyskinesia. Turk Thorac J 18(1):19\u201322. https:\/\/doi.org\/10.5152\/TurkThoracJ.2017.16049","journal-title":"Turk Thorac J"},{"issue":"6","key":"6019_CR9","doi-asserted-by":"publisher","first-page":"68","DOI":"10.3810\/pgm.2010.11.2225","volume":"122","author":"DE Forman","year":"2010","unstructured":"Forman DE, Myers J, Lavie CJ, Guazzi M, Celli B, Arena R (2010) Cardiopulmonary exercise testing: relevant but underused. Postgrad Med 122(6):68\u201386. https:\/\/doi.org\/10.3810\/pgm.2010.11.2225","journal-title":"Postgrad Med"},{"issue":"8","key":"6019_CR10","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201908-1590ST","volume":"200","author":"BL Graham","year":"2019","unstructured":"Graham BL, Steenbruggen I, Miller MR, Barjaktarevic IZ, Cooper BG, Hall GL, Hallstrand TS, Kaminsky DA, McCarthy K, McCormack MC, Oropez CE, Rosenfeld M, Stanojevic S, Swanney MP, Thompson BR (2019) Standardization of spirometry 2019 update. An official American Thoracic Society and European Respiratory Society technical statement. Am J Respir Crit Care Med 200(8):e70. https:\/\/doi.org\/10.1164\/rccm.201908-1590ST","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"6019_CR11","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1183\/09031936.00150314","volume":"44","author":"AE Holland","year":"2014","unstructured":"Holland AE, Spruit MA, Troosters T, Puhan MA, Pepin V, Saey D, McCormack MC, Carlin BW, Sciurba FC, Pitta F, Wanger J, MacIntyre N, Kaminsky DA, Culver BH, Revill SM, Hernandes NA, Andrianopoulos V, Camillo CA, Mitchell KE, Lee AL, Hill CJ, Singh SJ (2014) An official European Respiratory Society\/American Thoracic Society technical standard: field walking tests in chronic respiratory disease. Eur Respir J 44(6):1428\u20131446. https:\/\/doi.org\/10.1183\/09031936.00150314","journal-title":"Eur Respir J"},{"issue":"4","key":"6019_CR12","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1159\/000485464","volume":"95","author":"E Hulzebos","year":"2018","unstructured":"Hulzebos E, Takken T, Reijneveld EA, Mulder MMG, Bongers BC (2018) Reference values for respiratory muscle strength in children and adolescents. Respiration 95(4):235\u2013243. https:\/\/doi.org\/10.1159\/000485464","journal-title":"Respiration"},{"issue":"2","key":"6019_CR13","doi-asserted-by":"publisher","first-page":"104","DOI":"10.5152\/akd.2010.032","volume":"10","author":"D Inal-Ince","year":"2010","unstructured":"Inal-Ince D, Savci S, Arikan H, Saglam M, Bosnak-Guclu M, Tokgozoglu L, Coplu L (2010) Cardiac autonomic responses to exercise testing in patients with chronic obstructive pulmonary disease. Anadolu Kardiyol Derg 10(2):104\u2013110. https:\/\/doi.org\/10.5152\/akd.2010.032","journal-title":"Anadolu Kardiyol Derg"},{"key":"6019_CR14","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.congress-2016.PA531","author":"D Inal-Ince","year":"2016","unstructured":"Inal-Ince D, Simsek S, Saglam M, Sonbahar-Ulu H, Cakmak A, Calik-Kutukcu E, Vardar-Yagli N, Bozdemir-Ozel C, Emiralioglu N, Ozcelik U, Kiper N, Arikan H (2016) Presence of Kartagener syndrome reduces exercise capacity in primary ciliary dyskinesia. Eur Respir J\u00a0https:\/\/doi.org\/10.1183\/13993003.congress-2016.PA531","journal-title":"Eur Respir J"},{"key":"6019_CR15","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.974363","volume":"10","author":"T Jones","year":"2022","unstructured":"Jones T, Baque E, O\u2019Grady KAF, Goyal V, Chang AB, Trost SG (2022) Barriers and facilitators of physical activity in children with bronchiectasis: perspectives from children and parents. Front Pediatr 10:974363. https:\/\/doi.org\/10.3389\/fped.2022.974363","journal-title":"Front Pediatr"},{"issue":"3","key":"6019_CR16","doi-asserted-by":"publisher","first-page":"309","DOI":"10.24953\/turkjpediatr.2024.4581","volume":"66","author":"Y Kartal","year":"2024","unstructured":"Kartal Y, Bozdemir Ozel C, Cakmak A, Sonbahar Ulu H, Inal Ince D, Ademhan Tural D, Eryilmaz Polat S, Hizal M, Ozcelik U, Karahan S, Budak MT, Girgin G, Arikan H, Sabuncuoglu S (2024) The relationship between lung function, exercise capacity, oxidant and antioxidant response in primary ciliary dyskinesia and cystic fibrosis. Turk J Pediatr 66(3):309\u2013322. https:\/\/doi.org\/10.24953\/turkjpediatr.2024.4581","journal-title":"Turk J Pediatr"},{"issue":"8","key":"6019_CR17","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1164\/rccm.201301-0059CI","volume":"188","author":"MR Knowles","year":"2013","unstructured":"Knowles MR, Daniels LA, Davis SD, Zariwala MA, Leigh MW (2013) Primary ciliary dyskinesia. Recent advances in diagnostics, genetics, and characterization of clinical disease. Am J Respir Crit Care Med 188(8):913\u2013922. https:\/\/doi.org\/10.1164\/rccm.201301-0059CI","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"6019_CR18","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/j.ccm.2016.04.008","volume":"37","author":"MR Knowles","year":"2016","unstructured":"Knowles MR, Zariwala M, Leigh M (2016) Primary ciliary dyskinesia. Clin Chest Med 37(3):449\u2013461. https:\/\/doi.org\/10.1016\/j.ccm.2016.04.008","journal-title":"Clin Chest Med"},{"issue":"6","key":"6019_CR19","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1001\/jama.281.6.524","volume":"281","author":"MS Lauer","year":"1999","unstructured":"Lauer MS, Francis GS, Okin PM, Pashkow FJ, Snader CE, Marwick TH (1999) Impaired chronotropic response to exercise stress testing as a predictor of mortality. Jama-J Am Med Assoc 281(6):524\u2013529. https:\/\/doi.org\/10.1001\/jama.281.6.524","journal-title":"Jama-J Am Med Assoc"},{"issue":"2","key":"6019_CR20","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1183\/09031936.00216214","volume":"46","author":"JS Lucas","year":"2015","unstructured":"Lucas JS, Behan L, Dunn Galvin A, Alpern A, Morris AM, Carroll MP, Knowles MR, Leigh MW, Quittner AL (2015) A quality-of-life measure for adults with primary ciliary dyskinesia: QOL-PCD. Eur Respir J 46(2):375\u2013383. https:\/\/doi.org\/10.1183\/09031936.00216214","journal-title":"Eur Respir J"},{"issue":"2","key":"6019_CR21","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1590\/s0066-782x2011005000078","volume":"97","author":"FA Machado","year":"2011","unstructured":"Machado FA, Denadai BS (2011) Validity of maximum heart rate prediction equations for children and adolescents. Arq Bras Cardiol 97(2):136\u2013140. https:\/\/doi.org\/10.1590\/s0066-782x2011005000078","journal-title":"Arq Bras Cardiol"},{"issue":"8","key":"6019_CR22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071409","volume":"8","author":"A Madsen","year":"2013","unstructured":"Madsen A, Green K, Buchvald F, Hanel B, Nielsen KG (2013) Aerobic fitness in children and young adults with primary ciliary dyskinesia. PLoS ONE 8(8):e71409. https:\/\/doi.org\/10.1371\/journal.pone.0071409","journal-title":"PLoS ONE"},{"issue":"12","key":"6019_CR23","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1080\/17476348.2016.1258305","volume":"10","author":"CF Mylius","year":"2016","unstructured":"Mylius CF, Paap D, Takken T (2016) Reference value for the 6-minute walk test in children and adolescents: a systematic review. Expert Rev Respir Med 10(12):1335\u20131352. https:\/\/doi.org\/10.1080\/17476348.2016.1258305","journal-title":"Expert Rev Respir Med"},{"issue":"1","key":"6019_CR24","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1002\/ajmg.c.31967","volume":"190","author":"KG Nielsen","year":"2022","unstructured":"Nielsen KG, Holgersen MG, Crowley S, Marthin JK (2022) Chronic airway disease in primary ciliary dyskinesia-spiced with geno-phenotype associations. Am J Med Genet C Semin Med Genet 190(1):20\u201335. https:\/\/doi.org\/10.1002\/ajmg.c.31967","journal-title":"Am J Med Genet C Semin Med Genet"},{"issue":"4","key":"6019_CR25","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.pulmoe.2019.02.009","volume":"25","author":"T Pinho","year":"2019","unstructured":"Pinho T, Jacome C, Pinto J, Marques A (2019) Reference equation for the incremental shuttle walk test in Portuguese children and adolescents. Pulmonology 25(4):208\u2013214. https:\/\/doi.org\/10.1016\/j.pulmoe.2019.02.009","journal-title":"Pulmonology"},{"issue":"1","key":"6019_CR26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0209897","volume":"14","author":"JM Rossi Neto","year":"2019","unstructured":"Rossi Neto JM, Tebexreni AS, Alves ANF, Smanio PEP, de Abreu FB, Thomazi MC, Nishio PA, Cuninghant IA (2019) Cardiorespiratory fitness data from 18,189 participants who underwent treadmill cardiopulmonary exercise testing in a Brazilian population. PLoS ONE 14(1):e0209897. https:\/\/doi.org\/10.1371\/journal.pone.0209897","journal-title":"PLoS ONE"},{"issue":"9","key":"6019_CR27","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1111\/ped.12919","volume":"58","author":"M Saglam","year":"2016","unstructured":"Saglam M, Vardar-Yagli N, Savci S, Inal-Ince D, Aribas Z, Bosnak-Guclu M, Arikan H, Calik-Kutukcu E, Gunes-Yalcin E (2016) Six minute walk test versus incremental shuttle walk test in cystic fibrosis. Pediatr Int 58(9):887\u2013893. https:\/\/doi.org\/10.1111\/ped.12919","journal-title":"Pediatr Int"},{"issue":"5","key":"6019_CR28","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1007\/s00431-018-3121-2","volume":"177","author":"S Simsek","year":"2018","unstructured":"Simsek S, Inal-Ince D, Cakmak A, Emiralioglu N, Calik-Kutukcu E, Saglam M, Vardar-Yagli N, Ozcelik HU, Sonbahar-Ulu H, Bozdemir-Ozel C, Kiper N, Arikan H (2018) Reduced anaerobic and aerobic performance in children with primary ciliary dyskinesia. Eur J Pediatr 177(5):765\u2013773. https:\/\/doi.org\/10.1007\/s00431-018-3121-2","journal-title":"Eur J Pediatr"},{"issue":"11","key":"6019_CR29","doi-asserted-by":"publisher","first-page":"2016","DOI":"10.1183\/09031936.94.07112016","volume":"7","author":"SJ Singh","year":"1994","unstructured":"Singh SJ, Morgan MD, Hardman AE, Rowe C, Bardsley PA (1994) Comparison of oxygen uptake during a conventional treadmill test and the shuttle walking test in chronic airflow limitation. Eur Respir J 7(11):2016\u20132020","journal-title":"Eur Respir J"},{"issue":"6","key":"6019_CR30","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1183\/09031936.00150414","volume":"44","author":"SJ Singh","year":"2014","unstructured":"Singh SJ, Puhan MA, Andrianopoulos V, Hernandes NA, Mitchell KE, Hill CJ, Lee AL, Camillo CA, Troosters T, Spruit MA, Carlin BW, Wanger J, Pepin V, Saey D, Pitta F, Kaminsky DA, McCormack MC, MacIntyre N, Culver BH, Sciurba FC, Revill SM, Delafosse V, Holland AE (2014) An official systematic review of the European Respiratory Society\/American Thoracic Society: measurement properties of field walking tests in chronic respiratory disease. Eur Respir J 44(6):1447\u20131478. https:\/\/doi.org\/10.1183\/09031936.00150414","journal-title":"Eur Respir J"},{"issue":"1","key":"6019_CR31","doi-asserted-by":"publisher","DOI":"10.1111\/ped.14979","volume":"64","author":"H Sonbahar-Ulu","year":"2022","unstructured":"Sonbahar-Ulu H, Cakmak A, Inal-Ince D, Vardar-Yagli N, Yatar I, Calik-Kutukcu E, Saglam M, Tekerlek H, Bozdemir-Ozel C, Arikan H, Emiralioglu N, Ozcelik U (2022) Physical fitness and activities of daily living in primary ciliary dyskinesia: a retrospective study. Pediatr Int 64(1):e14979. https:\/\/doi.org\/10.1111\/ped.14979","journal-title":"Pediatr Int"},{"key":"6019_CR32","doi-asserted-by":"publisher","first-page":"PA5047","DOI":"10.1183\/13993003.congress-2023.PA5047","volume":"62","author":"H Sonbahar-Ulu","year":"2023","unstructured":"Sonbahar-Ulu H, Inal-Ince D, Cakmak A, Saglam M, Yagli NV, Kutukcu EC, Ozcelik U (2023) Inspiratory muscle strength is an independent predictor for six-minute walk distance in primary ciliary dyskinesia. Eur Respir J 62:PA5047. https:\/\/doi.org\/10.1183\/13993003.congress-2023.PA5047","journal-title":"Eur Respir J"},{"issue":"7","key":"6019_CR33","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1080\/17476348.2020.1752195","volume":"14","author":"T Takken","year":"2020","unstructured":"Takken T, Ulu HS, Hulzebos EHJ (2020) Clinical recommendations for cardiopulmonary exercise testing in children with respiratory diseases. Expert Rev Respir Med 14(7):691\u2013701. https:\/\/doi.org\/10.1080\/17476348.2020.1752195","journal-title":"Expert Rev Respir Med"},{"issue":"6","key":"6019_CR34","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1111\/j.1365-2362.2011.02626.x","volume":"42","author":"G Valerio","year":"2012","unstructured":"Valerio G, Giallauria F, Montella S, Vaino N, Vigorito C, Mirra V, Santamaria F (2012) Cardiopulmonary assessment in primary ciliary dyskinesia. Eur J Clin Invest 42(6):617\u2013622. https:\/\/doi.org\/10.1111\/j.1365-2362.2011.02626.x","journal-title":"Eur J Clin Invest"},{"issue":"3","key":"6019_CR35","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.hrtlng.2016.03.001","volume":"45","author":"EH Van Iterson","year":"2016","unstructured":"Van Iterson EH, Wheatley CM, Baker SE, Morgan WJ, Snyder EM (2016) The relationship between cardiac hemodynamics and exercise tolerance in cystic fibrosis. Heart Lung 45(3):283\u2013290. https:\/\/doi.org\/10.1016\/j.hrtlng.2016.03.001","journal-title":"Heart Lung"},{"issue":"1","key":"6019_CR36","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1203\/PDR.0b013e3181fff35f","volume":"69","author":"GD Wells","year":"2011","unstructured":"Wells GD, Wilkes DL, Schneiderman JE, Rayner T, Elmi M, Selvadurai H, Dell SD, Noseworthy MD, Ratjen F, Tein I, Coates AL (2011) Skeletal muscle metabolism in cystic fibrosis and primary ciliary dyskinesia. Pediatr Res 69(1):40\u201345. https:\/\/doi.org\/10.1203\/PDR.0b013e3181fff35f","journal-title":"Pediatr Res"}],"container-title":["European Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00421-025-06019-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00421-025-06019-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00421-025-06019-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T12:12:07Z","timestamp":1778674327000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00421-025-06019-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,4]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["6019"],"URL":"https:\/\/doi.org\/10.1007\/s00421-025-06019-2","relation":{},"ISSN":["1439-6319","1439-6327"],"issn-type":[{"value":"1439-6319","type":"print"},{"value":"1439-6327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,4]]},"assertion":[{"value":"30 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Hacettepe University's Non-Interventional Clinical Research Ethical Board approved the study with approval number GO 20\/647. This study was conducted in accordance with the Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All participants and their parents were informed about the study protocol and signed an informed consent form.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}