{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T22:51:24Z","timestamp":1785279084430,"version":"3.55.0"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2006,2,21]],"date-time":"2006-02-21T00:00:00Z","timestamp":1140480000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Langenbecks Arch Surg"],"published-print":{"date-parts":[[2006,6]]},"DOI":"10.1007\/s00423-005-0015-3","type":"journal-article","created":{"date-parts":[[2006,2,20]],"date-time":"2006-02-20T14:41:46Z","timestamp":1140446506000},"page":"195-202","source":"Crossref","is-referenced-by-count":52,"title":["Early and enduring nutritional and functional results of pylorus preservation vs classic Whipple procedure for pancreatic cancer"],"prefix":"10.1007","volume":"391","author":[{"given":"Marco","family":"Niedergethmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Farag Soliman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Saar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salih","family":"Berisha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Willeke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Post","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,2,21]]},"reference":[{"key":"15_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1072-7515(99)00075-7","volume":"189","author":"SF Sener","year":"1999","unstructured":"Sener SF, Fremgen A, Menck HR, Winchester DP (1999) Pancreatic cancer: a report of treatment and survival trends for 100,313 patients diagnosed from 1985\u20131995, using the National Cancer Database. J Am Coll Surg 189:1\u20137","journal-title":"J Am Coll Surg"},{"key":"15_CR2","first-page":"6","volume":"168","author":"A Richter","year":"2002","unstructured":"Richter A, Niedergethmann M, Hartel M, Sturm JW, Lorenz D, Trede M, Post S (2002) Resection for malignancies of the pancreatic head in patients over 70 years. Eur J Surg 168:6","journal-title":"Eur J Surg"},{"key":"15_CR3","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1097\/00000658-199004000-00011","volume":"211","author":"M Trede","year":"1990","unstructured":"Trede M, Schwall G, Saeger HD (1990) Survival after pancreatduodenectomy. 118 consecutive resections without an operative mortality. Ann Surg 211:447\u2013451","journal-title":"Ann Surg"},{"key":"15_CR4","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/S0039-6109(05)70146-8","volume":"81","author":"M Trede","year":"2001","unstructured":"Trede M, Richter A, Wendl K (2001) Personal observations, opinions, and approaches to cancer of the pancreas and the periampullary area. Surg Clin North Am 81:595\u2013610","journal-title":"Surg Clin North Am"},{"key":"15_CR5","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s004230050004","volume":"385","author":"C Gebhardt","year":"2000","unstructured":"Gebhardt C, Meyer W, Reichel M, W\u00fcnsch PH (2000) Prognostic factors in the operative treatment of ductal pancreatic carcinoma. Langenbecks Arch Surg 385:14","journal-title":"Langenbecks Arch Surg"},{"key":"15_CR6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1097\/00000658-199709000-00004","volume":"226","author":"CJ Yeo","year":"1997","unstructured":"Yeo CJ, Cameron JL, Sohn TA, Lillemoe KD, Pitt HA, Talamini MA et al (1997) Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Ann Surg 226:248\u2013257","journal-title":"Ann Surg"},{"issue":"95","key":"15_CR7","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1002\/cncr.10758","volume":"15","author":"H Oettle","year":"2002","unstructured":"Oettle H, Riess H (2002) Gemcitabine in combination with 5-fluorouracil with or without folinic acid in the treatment of pancreatic cancer. Cancer 15(95):912\u2013922","journal-title":"Cancer"},{"key":"15_CR8","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1097\/00000658-200112000-00007","volume":"234","author":"JP Neoptolemos","year":"2001","unstructured":"Neoptolemos JP, Stocken DD, Dunn JA, Almond J, Beger HG, Pederzoli P et al (2001) Influence of resection margins on survival for patients with pancreatic cancer treated by adjuvant chemoradiation and\/or chemotherapy in the ESPAC-1 randomized controlled trial. Ann Surg 234:758\u2013768","journal-title":"Ann Surg"},{"key":"15_CR9","first-page":"175","volume":"59","author":"M Niedergethmann","year":"2004","unstructured":"Niedergethmann M, Farag-Soliman M, Post S (2004) Postoperative complications of pancreatic cancer surgery. Minerva Chir 59:175\u2013183","journal-title":"Minerva Chir"},{"key":"15_CR10","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1097\/00000658-200012000-00007","volume":"232","author":"DJ Gouma","year":"2000","unstructured":"Gouma DJ, van Geenen RC, van Gulik TM, de Haan RJ, de Wit LT, Busch OR et al (2000) Rates of complications and death after pancreaticoduodenectomy: risk factors and the impact of hospital volume. Ann Surg 232:786\u2013795","journal-title":"Ann Surg"},{"key":"15_CR11","first-page":"846","volume":"50","author":"T Ohtsuka","year":"2003","unstructured":"Ohtsuka T, Yamaguchi K, Ohuchida J, Inoue K, Nagai E, Chijiwa K, Tanaka M (2003) Comparison of quality of life after pylorus-preserving pancreatoduodenectomy and Whipple resection. Hepatogastroenterology 50:846\u2013850","journal-title":"Hepatogastroenterology"},{"key":"15_CR12","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/00006676-200401000-00011","volume":"28","author":"O Horstmann","year":"2004","unstructured":"Horstmann O, Markus P, Ghadimi M, Becker H (2004) Pylorus preservation has no impact on delayed gastric emptying after pancreatic head resection. Pancreas 28:69\u201374","journal-title":"Pancreas"},{"key":"15_CR13","first-page":"443","volume":"178","author":"W Kozuscheck","year":"1994","unstructured":"Kozuscheck W, Reith HB, Waleczek H, Haarmann W, Edelmann M, Sonntag D (1994) A comparison of long-term results of the standard Whipple procedure and the pylorus preserving pancreatoduodenectomy. J Am Coll Surg 178:443","journal-title":"J Am Coll Surg"},{"key":"15_CR14","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1007\/PL00002580","volume":"70","author":"FA Wenger","year":"1999","unstructured":"Wenger FA, Jacobi CA, Haubold K, Zieren HU, M\u00fcller JM (1999) Gastrointestinal quality of life after duodenopancreatectomy in pancreatic carcinoma. Preliminary results of a prospective randomized study: pancreatoduodenectomy or pylorus-preserving pancreatoduodenectomy. Chirurg 70:1454\u20131459","journal-title":"Chirurg"},{"key":"15_CR15","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1159\/000050193","volume":"18","author":"C Bassi","year":"2001","unstructured":"Bassi C, Falconi M, Salvia R, Mascetta G, Molinari E, Pederzoli P (2001) Management of complications after pancreaticoduodectomy in a high volume centre: results on 150 consecutive patients. Dig Surg 18:453\u2013458","journal-title":"Dig Surg"},{"key":"15_CR16","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1097\/00000658-199510000-00014","volume":"222","author":"CJ Yeo","year":"1995","unstructured":"Yeo CJ, Cameron JL, Maher MM, Sauter PK, Zahurak ML, Talamini MA et al (1995) A prospective randomized trial of pancreaticogastrostomy versus pancreaticojejunostomy after pancreaticoduodenectomy. Ann Surg 222:580\u2013588","journal-title":"Ann Surg"},{"key":"15_CR17","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1097\/01.sla.0000143248.71964.29","volume":"240","author":"KT Tran","year":"2004","unstructured":"Tran KT, Smeenk HG, van Eijck CH, Kazemier G, Hop WC, Greve JW, Terpstra OT, Zijlstra JA, Klinkert P, Jeekel H (2004) Pylorus preserving pancreaticoduodenectomy versus standard Whipple procedure: a prospective, randomized, multicenter analysis of 170 patients with pancreatic and periampullary tumors. Ann Surg 240:738\u2013745","journal-title":"Ann Surg"},{"key":"15_CR18","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1007\/s002689900600","volume":"23","author":"V Carlo Di","year":"1999","unstructured":"Di Carlo V, Zerbi A, Balzano G, Corso V (1999) Pylorus-preserving pancreaticoduodenectomy versus conventional Whipple operation. World J Surg 23:920\u2013929","journal-title":"World J Surg"},{"key":"15_CR19","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/00000658-199208000-00004","volume":"216","author":"JHG Klinkenbijl","year":"1992","unstructured":"Klinkenbijl JHG, van der Schelling GP, Hop WCJ, van Pel R, Bruining HA, Jeekel J (1992) The advantages of pylorus preserving pancreatoduodenectomy in malignant disease of the pancreas and periampullary region. Ann Surg 216:142\u2013147","journal-title":"Ann Surg"},{"key":"15_CR20","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1046\/j.1365-2168.1999.01074.x","volume":"86","author":"PW Lin","year":"1999","unstructured":"Lin PW, Lin YJ (1999) Prospective randomized comparison between pylorus-preserving and standard pancreaticoduodenectomy. Br J Surg 86:603\u2013607","journal-title":"Br J Surg"},{"key":"15_CR21","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S1091-255X(00)80084-0","volume":"4","author":"CA Seiler","year":"2000","unstructured":"Seiler CA, Wagner M, Sadowski C, Kulli C, B\u00fcchler MW (2000) Randomized prospective trial of pylorus-preserving vs. classic duodenopancreatectomy (Whipple procedure): initial clinical results. J Gastrointest Surg 4:443\u2013452","journal-title":"J Gastrointest Surg"},{"key":"15_CR22","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/s004230050213","volume":"384","author":"O Horstmann","year":"1999","unstructured":"Horstmann O, Becker H, Post S, Nustede R (1999) Is delayed gastric emptying following pancreaticoduodenectomy related to pylorus preservation? Langenbecks Arch Surg 384:354\u2013359","journal-title":"Langenbecks Arch Surg"},{"key":"15_CR23","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1002\/bjs.18003112406","volume":"31","author":"K Watson","year":"1944","unstructured":"Watson K (1944) Carcinoma of ampulla of Vater. Successful radical resection. Br J Surg 31:368","journal-title":"Br J Surg"},{"key":"15_CR24","first-page":"959","volume":"146","author":"LW Traverso","year":"1978","unstructured":"Traverso LW, Longmire WP (1978) Preservation of the pylorus in pancreaticoduodenectomy. Surg Gynecol Obstet 146:959\u2013962","journal-title":"Surg Gynecol Obstet"},{"key":"15_CR25","first-page":"124","volume-title":"Das Pankreaskarzinom","author":"S Post","year":"2003","unstructured":"Post S, Niedergethmann M (2003) Die Resektion des Pankreaskopftumors. In: B\u00fcchler MW, L\u00f6hr JM (eds) Das Pankreaskarzinom. Unimed Verlag, Bremen, pp 124\u2013140"},{"key":"15_CR26","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1159\/000172291","volume":"11","author":"CA Seiler","year":"1994","unstructured":"Seiler CA, Wagner M, B\u00fcchler MW (1994) The role of pylorus-preserving duodenopancreatectomy in pancreatic cancer. Dig Surg 11:390\u2013396","journal-title":"Dig Surg"},{"key":"15_CR27","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1097\/01.sla.0000144690.54204.d3","volume":"240","author":"RH Bell","year":"2004","unstructured":"Bell RH (2004) Save the pylori. Ann Surg 240:746\u2013747","journal-title":"Ann Surg"},{"key":"15_CR28","first-page":"1","volume":"160","author":"AL Warshaw","year":"1985","unstructured":"Warshaw AL, Torchiana DL (1985) Delayed gastric emptying after pylorus preserving pancreaticoduodenectomy. Surg Gynecol Obstet 160:1","journal-title":"Surg Gynecol Obstet"},{"key":"15_CR29","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1002\/bjs.1800821235","volume":"82","author":"JD Roder","year":"1995","unstructured":"Roder JD, Stein HJ, Huttl W, Siewert JR (1995) Pylorus preserving versus standard pancreatoduodenectomy. Br J Surg 82:975","journal-title":"Br J Surg"},{"key":"15_CR30","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1097\/00000658-200202000-00012","volume":"235","author":"H Murakami","year":"2002","unstructured":"Murakami H, Suzuki H, Nakamura T (2002) Pancreatic fibrosis correlates with delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy with pancreaticogastrostomy. Ann Surg 235:240\u2013245","journal-title":"Ann Surg"},{"key":"15_CR31","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/S1091-255X(03)00109-4","volume":"7","author":"H Riediger","year":"2003","unstructured":"Riediger H, Makowiec F, Schareck WD, Hopt UT, Adam U (2003) Delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy is strongly related to other postoperative complications. J Gastrointest Surg 7:758\u2013765","journal-title":"J Gastrointest Surg"},{"issue":"358","key":"15_CR32","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1016\/S0140-6736(01)06666-1","volume":"10","author":"RA Abrams","year":"2001","unstructured":"Abrams RA, Lillemoe KD, Piantadosi S (2001) Continuing controversy over adjuvant therapy of pancreatic cancer. Lancet 10(358):1565\u20131566","journal-title":"Lancet"},{"key":"15_CR33","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S1072-7515(97)00078-1","volume":"185","author":"MI Berge Henegouwen Van","year":"1997","unstructured":"Van Berge Henegouwen MI, van Gulik TM, DeWit LT, Allema JH, Rauws EA, Obertop H (1997) Delayed gastric emptying after standard pancreaticoduodenectomy versus pylorus-preserving pancreaticoduodenectomy: an analysis of 200 consecutive patients. J Am Coll Surg 185:373\u2013379","journal-title":"J Am Coll Surg"},{"key":"15_CR34","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1097\/00000658-199305010-00002","volume":"217","author":"JL Cameron","year":"1993","unstructured":"Cameron JL, Pitt HA, Yeo CJ, Lillemoe KD, Kaufman HS, Coleman J (1993) One hundred and forty-five consecutive pancreaticoduodenectomies without mortality. Ann Surg 217:430\u2013435","journal-title":"Ann Surg"},{"key":"15_CR35","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/0022-4804(87)90022-9","volume":"42","author":"M Tanaka","year":"1987","unstructured":"Tanaka M, Sarr MG (1987) Total duodenectomy: effect on canine gastrointestinal motility. J Surg Res 42:483\u2013493","journal-title":"J Surg Res"},{"key":"15_CR36","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1002\/bjs.1800730824","volume":"73","author":"PA Grace","year":"1986","unstructured":"Grace PA, Pitt HA, Longmire WP (1986) Pancreaticoduodenectomy with pylorus preservation for adenocarcinoma of the head of the pancreas. Br J Surg 73:647\u2013650","journal-title":"Br J Surg"},{"key":"15_CR37","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1097\/00000658-198612000-00007","volume":"204","author":"KM Itani","year":"1986","unstructured":"Itani KM, Coleman RE, Meyers WC (1986) Pylorus-preserving pancreaticoduodenectomy. A clinical and physiological appraisal. Ann Surg 204:655\u2013664","journal-title":"Ann Surg"},{"key":"15_CR38","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1097\/00000658-200111000-00013","volume":"234","author":"S Ohwada","year":"2001","unstructured":"Ohwada S, Satoh Y, Kawate S, Yamada T, Kawamura O, Koyama T et al (2001) Low-dose erythromycin reduces delayed gastric emptying and improves gastric motility after Billroth I pylorus-preserving-pancreaticoduodenectomy. Ann Surg 234:668\u2013674","journal-title":"Ann Surg"},{"key":"15_CR39","doi-asserted-by":"crossref","unstructured":"Boettger TC, Engelmann R, Junginger T (2002) Ante-oder retrokolische Duodenojejunostomie nach pyloruserhaltender Duodenopankreatektomie\u2014eine prospektiv randomisierte Studie. Langenbecks Arch Surg","DOI":"10.1007\/978-3-642-55715-6_23"},{"key":"15_CR40","first-page":"208","volume":"78","author":"T Ohta","year":"1993","unstructured":"Ohta T, Nagakawa Z, Ueno K (1993) The mode of lymphatic and local spread of pancreatic carcinoma less than 4.0 in size. Int Surg 78:208","journal-title":"Int Surg"},{"issue":"8","key":"15_CR41","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S0748-7983(03)00124-0","volume":"29","author":"R Gupta","year":"2003","unstructured":"Gupta R, Ihmaidat H (2003) Nutritional effects of oesophageal, gastric and pancreatic carcinoma. Eur J Surg Oncol 29(8):634\u2013643","journal-title":"Eur J Surg Oncol"},{"issue":"1","key":"15_CR42","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/bjc.1997.17","volume":"75","author":"SJ Wigmore","year":"1997","unstructured":"Wigmore SJ, Plester CE, Richardson RA, Fearon KC (1997) Changes in nutritional status associated with unresectable pancreatic cancer. Br J Cancer 75(1):106\u2013109","journal-title":"Br J Cancer"},{"issue":"4","key":"15_CR43","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1001\/jama.1980.03310040056033","volume":"244","author":"WD Wys De","year":"1980","unstructured":"De Wys WD (1980) Nutritional care of the cancer patient. JAMA 244(4):374\u2013376","journal-title":"JAMA"},{"key":"15_CR44","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1097\/00000658-199410000-00003","volume":"220","author":"MF Brennan","year":"1994","unstructured":"Brennan MF, Pisters PW, Posner M et al (1994) A prospective randomized trial of total parenteral nutrition after major pancreatic resection for malignancy. Ann Surg 220:436\u2013441","journal-title":"Ann Surg"},{"key":"15_CR45","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/0899-9007(95)00065-8","volume":"12","author":"A Giacosa","year":"1996","unstructured":"Giacosa A, Frascio F, Sukkar SG, Roncella S (1996) Food intake and body composition in cancer cachexia. Nutrition 12:20\u201323","journal-title":"Nutrition"},{"issue":"3","key":"15_CR46","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1177\/0148607188012003286","volume":"12","author":"KA Kern","year":"1988","unstructured":"Kern KA, Norton JA (1988) Cancer cachexia. JPEN J Parenter Enteral Nutr 12(3):286\u2013298","journal-title":"JPEN J Parenter Enteral Nutr"}],"container-title":["Langenbeck's Archives of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-005-0015-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00423-005-0015-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-005-0015-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T20:36:53Z","timestamp":1559075813000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00423-005-0015-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2,21]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["15"],"URL":"https:\/\/doi.org\/10.1007\/s00423-005-0015-3","relation":{},"ISSN":["1435-2443","1435-2451"],"issn-type":[{"value":"1435-2443","type":"print"},{"value":"1435-2451","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2,21]]}}}