{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T09:22:40Z","timestamp":1787563360776,"version":"build-2736575974"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2013,7,5]],"date-time":"2013-07-05T00:00:00Z","timestamp":1372982400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Langenbecks Arch Surg"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1007\/s00423-013-1097-y","type":"journal-article","created":{"date-parts":[[2013,7,4]],"date-time":"2013-07-04T03:49:02Z","timestamp":1372909742000},"page":"881-886","source":"Crossref","is-referenced-by-count":22,"title":["Risk factors for \u201cPTH spikes\u201d during surgery for primary hyperparathyroidism"],"prefix":"10.1007","volume":"398","author":[{"given":"Philipp","family":"Riss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Krall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Scheuba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Bieglmayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Niederle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,7,5]]},"reference":[{"key":"1097_CR1","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1001\/archsurg.137.6.659","volume":"137","author":"NT Jaskowiak","year":"2002","unstructured":"Jaskowiak NT, Sugg SL, Helke J, Koka MR, Kaplan EL (2002) Pitfalls of intraoperative quick parathyroid hormone monitoring and gamma probe localization in surgery for primary hyperparathyroidism. Arch Surg 137:659\u2013668, discussion 668\u20139","journal-title":"Arch Surg"},{"key":"1097_CR2","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1007\/BF03345256","volume":"26","author":"J Horanyi","year":"2003","unstructured":"Horanyi J, Duffek L, Szlavik R, Darvas K, Lakatos P, Toth M, Racz K (2003) Parathyroid surgical failures with misleading falls of intraoperative parathyroid hormone levels. J Endocrinol Investig 26:1095\u20131099","journal-title":"J Endocrinol Investig"},{"key":"1097_CR3","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1258\/000456305774538283","volume":"42","author":"IJ Phillips","year":"2005","unstructured":"Phillips IJ, Kurzawinski TR, Honour JW (2005) Potential pitfalls in intraoperative parathyroid hormone measurements during parathyroid surgery. Ann Clin Biochem 42:453\u2013458","journal-title":"Ann Clin Biochem"},{"key":"1097_CR4","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s00423-006-0125-6","volume":"392","author":"P Riss","year":"2007","unstructured":"Riss P, Kaczirek K, Bieglmayer C, Niederle B (2007) PTH spikes during parathyroid exploration\u2014a possible pitfall during PTH monitoring? Langenbeck\u2019s arch surg\/Deutsche Gesellschaft f\u00fcr Chirurgie 392:427\u2013430","journal-title":"Langenbeck\u2019s arch surg\/Deutsche Gesellschaft f\u00fcr Chirurgie"},{"key":"1097_CR5","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.amjoto.2009.07.003","volume":"31","author":"D Sidell","year":"2010","unstructured":"Sidell D, Wang J, Sercarz J (2010) Spurious decline in intraoperative parathyroid hormone: false positives in parathyroid surgery. Am J Otolaryngol 31:479\u2013481","journal-title":"Am J Otolaryngol"},{"key":"1097_CR6","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1007\/s00423-009-0532-6","volume":"394","author":"BJ Harrison","year":"2009","unstructured":"Harrison BJ, Triponez F (2009) Intraoperative adjuncts in surgery for primary hyperparathyroidism. Langenbeck\u2019s arch surg\/Deutsche Gesellschaft f\u00fcr Chirurgie 394:799\u2013809","journal-title":"Langenbeck\u2019s arch surg\/Deutsche Gesellschaft f\u00fcr Chirurgie"},{"key":"1097_CR7","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1093\/clinchem\/44.4.805","volume":"44","author":"R Lepage","year":"1998","unstructured":"Lepage R, Roy L, Brossard JH, Rousseau L, Dorais C, Lazure C, D\u2019Amour P (1998) A non-(1\u201384) circulating parathyroid hormone (PTH) fragment interferes significantly with intact PTH commercial assay measurements in uremic samples. Clin Chem 44:805\u2013809","journal-title":"Clin Chem"},{"key":"1097_CR8","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.surg.2006.07.016","volume":"140","author":"BS Miller","year":"2006","unstructured":"Miller BS, England BG, Nehs M, Burney RE, Doherty GM, Gauger PG (2006) Interpretation of intraoperative parathyroid hormone monitoring in patients with baseline parathyroid hormone levels of <100 pg\/mL. Surgery 140:883\u2013889, discussion 889\u201390","journal-title":"Surgery"},{"key":"1097_CR9","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1097\/SLA.0b013e3181d3d264","volume":"251","author":"MR Cook","year":"2010","unstructured":"Cook MR, Pitt SC, Schaefer S, Sippel R, Chen H (2010) A rising ioPTH level immediately after parathyroid resection: are additional hyperfunctioning glands always present? An application of the Wisconsin Criteria. Ann Surg 251:1127\u20131130","journal-title":"Ann Surg"},{"key":"1097_CR10","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1001\/archsurg.136.8.945","volume":"136","author":"GP Yang","year":"2001","unstructured":"Yang GP, Levine S, Weigel RJ (2001) A spike in parathyroid hormone during neck exploration may cause a false-negative intraoperative assay result. Arch Surg 136:945\u2013949, Chicago, Ill : 1960","journal-title":"Arch Surg"},{"key":"1097_CR11","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/s00423-009-0495-7","volume":"394","author":"P Riss","year":"2009","unstructured":"Riss P, Asari R, Scheuba C, Bieglmayer C, Niederle B (2009) PTH secretion of \u201cmanipulated\u201d parathyroid adenomas. Langenbeck\u2019s arch surg\/Deutsche Gesellschaft f\u00fcr Chirurgie 394:891\u2013895","journal-title":"Langenbeck\u2019s arch surg\/Deutsche Gesellschaft f\u00fcr Chirurgie"},{"key":"1097_CR12","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1007\/s001040050869","volume":"70","author":"G Prager","year":"1999","unstructured":"Prager G, Czerny C, Kurtaran A, Passler C, Scheuba C, Niederle B (1999) The value of preoperative localization studies in primary hyperparathyroidism. Der Chirurg; Zeitschrift f\u00fcr alle Gebiete der operativen Medizen 70:1082\u20131088","journal-title":"Der Chirurg; Zeitschrift f\u00fcr alle Gebiete der operativen Medizen"},{"key":"1097_CR13","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1001\/archsurg.136.7.810","volume":"136","author":"G Prager","year":"2001","unstructured":"Prager G, Czerny C, Kurtaran A, Passler C, Scheuba C, Bieglmayer C, Niederle B (2001) Minimally invasive open parathyroidectomy in an endemic goiter area: a prospective study. Arch Surg 136:810\u2013816, Chicago, Ill : 1960","journal-title":"Arch Surg"},{"key":"1097_CR14","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S1072-7515(02)01897-5","volume":"196","author":"G Prager","year":"2003","unstructured":"Prager G, Czerny C, Ofluoglu S, Kurtaran A, Passler C, Kaczirek K, Scheuba C, Niederle B (2003) Impact of localization studies on feasibility of minimally invasive parathyroidectomy in an endemic goiter region. J Am Coll Surg 196:541\u2013548","journal-title":"J Am Coll Surg"},{"key":"1097_CR15","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.surg.2007.05.004","volume":"142","author":"P Riss","year":"2007","unstructured":"Riss P, Kaczirek K, Heinz G, Bieglmayer C, Niederle B (2007) A \u201cdefined baseline\u201d in PTH monitoring increases surgical success in patients with multiple gland disease. Surgery 142:398\u2013404","journal-title":"Surgery"},{"key":"1097_CR16","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1093\/clinchem\/48.10.1731","volume":"48","author":"C Bieglmayer","year":"2002","unstructured":"Bieglmayer C, Prager G, Niederle B (2002) Kinetic analyses of parathyroid hormone clearance as measured by three rapid immunoassays during parathyroidectomy. Clin Chem 48:1731\u20131738","journal-title":"Clin Chem"},{"key":"1097_CR17","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/j.surg.2004.06.043","volume":"136","author":"DT Woodrum","year":"2004","unstructured":"Woodrum DT, Saunders BD, England BG, Burney RE, Doherty GM, Gauger PG (2004) The influence of sample site on intraoperative PTH monitoring during parathyroidectomy. Surgery 136:1169\u20131175","journal-title":"Surgery"},{"key":"1097_CR18","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0002-9610(91)90135-Z","volume":"162","author":"GL Irvin","year":"1991","unstructured":"Irvin GL, Dembrow VD, Prudhomme DL (1991) Operative monitoring of parathyroid gland hyperfunction. Am J Surg 162:299\u2013302","journal-title":"Am J Surg"},{"issue":"636","key":"1097_CR19","first-page":"638","volume":"81","author":"K Lorenz","year":"2010","unstructured":"Lorenz K, Dralle H (2010) Intraoperative parathyroid hormone determination for primary hyperparathyroidism. Der Chirurg; Zeitschrift f\u00fcr alle Gebiete der operativen Medizen 81(636):638\u2013642","journal-title":"Der Chirurg; Zeitschrift f\u00fcr alle Gebiete der operativen Medizen"},{"key":"1097_CR20","first-page":"1121","volume":"104","author":"SR Nussbaum","year":"1988","unstructured":"Nussbaum SR, Thompson AR, Hutcheson KA, Gaz RD, Wang CA (1988) Intraoperative measurement of parathyroid hormone in the surgical management of hyperparathyroidism. Surgery 104:1121\u20131127","journal-title":"Surgery"},{"key":"1097_CR21","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1007\/s00423-009-0505-9","volume":"394","author":"P Riss","year":"2009","unstructured":"Riss P, Scheuba C, Asari R, Bieglmayer C, Niederle B (2009) Is minimally invasive parathyroidectomy without QPTH monitoring justified? Langenbeck\u2019s arch surg\/Deutsche Gesellschaft f\u00fcr Chirurgie 394:875\u2013880","journal-title":"Langenbeck\u2019s arch surg\/Deutsche Gesellschaft f\u00fcr Chirurgie"},{"key":"1097_CR22","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1097\/SLA.0b013e3181dd4ee1","volume":"251","author":"RS Hwang","year":"2010","unstructured":"Hwang RS, Morris LF, Ro K, Park S, Ituarte PHG, Hong JC, Yeh MW (2010) A selective, Bayesian approach to intraoperative PTH monitoring. Ann Surg 251:1122\u20131126","journal-title":"Ann Surg"},{"key":"1097_CR23","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1002\/hed.21666","volume":"33","author":"G Bachar","year":"2011","unstructured":"Bachar G, Mizrachi A, Hadar T, Feinmesser R, Shpitzer T (2011) Role of parathyroid hormone monitoring during parathyroidectomy. Head & neck 33:1754\u20131757","journal-title":"Head & neck"},{"key":"1097_CR24","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1245\/s10434-009-0773-1","volume":"17","author":"LF Morris","year":"2010","unstructured":"Morris LF, Zanocco K, Ituarte PHG, Ro K, Duh Q-Y, Sturgeon C, Yeh MW (2010) The value of intraoperative parathyroid hormone monitoring in localized primary hyperparathyroidism: a cost analysis. Ann Surg Oncol 17:679\u2013685","journal-title":"Ann Surg Oncol"},{"key":"1097_CR25","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/j.surg.2011.09.008","volume":"150","author":"JC Hong","year":"2011","unstructured":"Hong JC, Morris LF, Park EJ, Ituarte PHG, Lee CH, Yeh MW (2011) Transient increases in intraoperative parathyroid levels related to anesthetic technique. Surgery 150:1069\u20131075","journal-title":"Surgery"},{"key":"1097_CR26","doi-asserted-by":"crossref","first-page":"3450","DOI":"10.1245\/s10434-009-0699-7","volume":"16","author":"AK Cayo","year":"2009","unstructured":"Cayo AK, Sippel RS, Schaefer S, Chen H (2009) Utility of intraoperative PTH for primary hyperparathyroidism due to multigland disease. Ann Surg Oncol 16:3450\u20133454","journal-title":"Ann Surg Oncol"},{"key":"1097_CR27","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1097\/SLA.0b013e3182306682","volume":"254","author":"P Riss","year":"2011","unstructured":"Riss P, Niederle B, Bieglmayer C (2011) A rising ioPTH level immediately after parathyroid resection: are additional hyperfunctioning glands always present? An application of the Wisconsin Criteria. Ann Surg 254:670\u2013671","journal-title":"Ann Surg"},{"key":"1097_CR28","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1007\/s00423-009-0510-z","volume":"394","author":"M Barczynski","year":"2009","unstructured":"Barczynski M, Konturek A, Hubalewska-Dydejczyk A, Cichon S, Nowak W (2009) Evaluation of Halle, Miami, Rome, and Vienna intraoperative iPTH assay criteria in guiding minimally invasive parathyroidectomy. Langenbeck\u2019s arch surg\/Deutsche Gesellschaft fur Chirurgie 394:843\u2013849","journal-title":"Langenbeck\u2019s arch surg\/Deutsche Gesellschaft fur Chirurgie"},{"key":"1097_CR29","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1245\/s10434-011-2192-3","volume":"19","author":"AE Reiher","year":"2012","unstructured":"Reiher AE, Schaefer S, Chen H, Sippel RS (2012) Does the final intraoperative PTH level really have to fall into the normal range to signify cure? Ann Surg Oncol 19:1862\u20131867","journal-title":"Ann Surg Oncol"},{"key":"1097_CR30","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1007\/s00268-005-7751-y","volume":"29","author":"I Emmolo","year":"2005","unstructured":"Emmolo I, Corso HD, Borretta G, Visconti G, Piovesan A, Cesario F, Borghi F (2005) Unexpected results using rapid intraoperative parathyroid hormone monitoring during parathyroidectomy for primary hyperparathyroidism. World J surg 29:785\u2013788","journal-title":"World J surg"},{"key":"1097_CR31","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1001\/archsurg.2011.5","volume":"146","author":"ML Richards","year":"2011","unstructured":"Richards ML, Thompson GB, Farley DR, Grant CS (2011) An optimal algorithm for intraoperative parathyroid hormone monitoring. Arch Surg 146:280\u2013285, Chicago, Ill : 1960","journal-title":"Arch Surg"},{"key":"1097_CR32","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1245\/s10434-011-2185-2","volume":"19","author":"E Kandil","year":"2012","unstructured":"Kandil E, Majid DS, Carson KA, Tufano RP (2012) A comparison of outcomes for younger and older adult patients undergoing surgery for primary hyperparathyroidism. Ann Surg Oncol 19:1897\u20131901","journal-title":"Ann Surg Oncol"},{"key":"1097_CR33","doi-asserted-by":"crossref","first-page":"2958","DOI":"10.1245\/s10434-010-1125-x","volume":"17","author":"JT Adler","year":"2010","unstructured":"Adler JT, Sippel RS, Chen H (2010) 25-hydroxyvitamin D status does not affect intraoperative parathyroid hormone dynamics in patients with primary hyperparathyroidism. Ann Surg Oncol 17:2958\u20132962","journal-title":"Ann Surg Oncol"}],"container-title":["Langenbeck's Archives of Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-013-1097-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00423-013-1097-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-013-1097-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T14:46:24Z","timestamp":1596033984000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00423-013-1097-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,5]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["1097"],"URL":"https:\/\/doi.org\/10.1007\/s00423-013-1097-y","relation":{},"ISSN":["1435-2443","1435-2451"],"issn-type":[{"value":"1435-2443","type":"print"},{"value":"1435-2451","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,5]]}}}