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Male sex [odds ratio (OR) 2.32], body mass index (BMI) \u2265\u200925\u00a0kg\/m<jats:sup>2<\/jats:sup> (OR 3.70), absence of diabetes mellitus (DM; HbA1c \u2264\u20096.2%; OR 3.62), and pancreatoduodenectomy (OR 3.06) were risk factors for PPH after all pancreatectomies. The PPH incidence was 0%, 1%, 2%, 6%, and 20% in patients with risk scores of 0 (<jats:italic>n<\/jats:italic>\u2009=\u200965), 1 (<jats:italic>n<\/jats:italic>\u2009=\u2009325), 2 (<jats:italic>n<\/jats:italic>\u2009=\u2009455), 3 (<jats:italic>n<\/jats:italic>\u2009=\u2009299), and 4 (<jats:italic>n<\/jats:italic>\u2009=\u200925), respectively. The differences between risk-score groups 0\u20132 (2%) and 3\u20134 (7%) were significant (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05, OR 4.7). In patients who had undergone pancreatoduodenectomy, postoperative pancreatic fistula (POPF; OR 31.7) and absence of DM (OR 3.45) were risk factors for PPH. There was no significant association between POPF and PPH after distal pancreatectomy (<jats:italic>P<\/jats:italic>\u2009=\u20090.28). The incidence of POPF post-pancreatoduodenectomy was 20%. BMI \u2265\u200925\u00a0kg\/m<jats:sup>2<\/jats:sup> (OR 3.17), serum albumin &lt;\u20093.5\u00a0g\/dl (OR 1.77), absence of DM (OR 1.75), distal extrahepatic bile duct carcinoma (OR 4.05), and carcinoma of the papilla of Vater (OR 5.19) were risk factors for POPF post-pancreatoduodenectomy.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Our study clarified the preoperative risk factors for PPH and recommends using a risk scoring system that includes \u201cabsence of DM\u201d for predicting PPH.<\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s00423-019-01830-w","type":"journal-article","created":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T03:58:13Z","timestamp":1571975893000},"page":"967-974","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Evaluation of preoperative risk factors for postpancreatectomy hemorrhage"],"prefix":"10.1007","volume":"404","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7348-1616","authenticated-orcid":false,"given":"Wataru","family":"Izumo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2423-4154","authenticated-orcid":false,"given":"Ryota","family":"Higuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takehisa","family":"Yazawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuichiro","family":"Uemura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Shiihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masakazu","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,10,24]]},"reference":[{"issue":"3","key":"1830_CR1","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1007\/s00534-007-1305-7","volume":"15","author":"W Kimura","year":"2008","unstructured":"Kimura W (2008) Strategies for the treatment of invasive ductal carcinoma of the pancreas and how to achieve zero mortality for pancreaticoduodenectomy. 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All procedures involving human participants were conducted in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration. This article does not contain any studies with animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}