{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:07:28Z","timestamp":1785416848845,"version":"3.56.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2021,1,8]],"date-time":"2021-01-08T00:00:00Z","timestamp":1610064000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,8]],"date-time":"2021-01-08T00:00:00Z","timestamp":1610064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Langenbecks Arch Surg"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s00423-020-02042-3","type":"journal-article","created":{"date-parts":[[2021,1,8]],"date-time":"2021-01-08T07:15:59Z","timestamp":1610090159000},"page":"1341-1351","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Early versus delayed (interval) appendicectomy for the management of appendicular abscess and phlegmon: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"406","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0325-8440","authenticated-orcid":false,"given":"Akinfemi A.","family":"Akingboye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1776-8828","authenticated-orcid":false,"given":"Fahad","family":"Mahmood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shafquat","family":"Zaman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima","family":"Mannan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1219-7571","authenticated-orcid":false,"given":"Ali Yasen Y.","family":"Mohamedahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,8]]},"reference":[{"issue":"8","key":"2042_CR1","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1002\/bjs.10151","volume":"103","author":"GlobalSurg_Collaborative","year":"2016","unstructured":"GlobalSurg_Collaborative (2016) Mortality of emergency abdominal surgery in high-, middle- and low-income countries. Br J Surg 103(8):971\u2013988","journal-title":"Br J Surg"},{"issue":"1","key":"2042_CR2","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.amjsurg.2019.04.018","volume":"219","author":"S Hajibandeh","year":"2020","unstructured":"Hajibandeh S, Hajibandeh S, Hobbs N, Mansour M (2020) Neutrophil-to-lymphocyte ratio predicts acute appendicitis and distinguishes between complicated and uncomplicated appendicitis: a systematic review and meta-analysis. Am J Surg 219(1):154\u2013163","journal-title":"Am J Surg"},{"issue":"5","key":"2042_CR3","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1093\/oxfordjournals.aje.a115734","volume":"132","author":"DG Addiss","year":"1990","unstructured":"Addiss DG, Shaffer N, Fowler BS, Tauxe RV (1990) The epidemiology of appendicitis and appendectomy in the United States. Am J Epidemiol 132(5):910\u2013925","journal-title":"Am J Epidemiol"},{"issue":"6","key":"2042_CR4","first-page":"CD011670","volume":"6","author":"Y Cheng","year":"2017","unstructured":"Cheng Y, Xiong X, Lu J, Wu S, Zhou R, Cheng N (2017) Early versus delayed appendicectomy for appendiceal phlegmon or abscess. Cochrane Database Syst Rev 6(6):CD011670","journal-title":"Cochrane Database Syst Rev"},{"issue":"5","key":"2042_CR5","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1097\/SLA.0b013e31811f3f9f","volume":"246","author":"RE Andersson","year":"2007","unstructured":"Andersson RE, Petzold MG (2007) Nonsurgical treatment of appendiceal abscess or phlegmon: a systematic review and meta-analysis. Ann Surg 246(5):741\u2013748","journal-title":"Ann Surg"},{"issue":"3","key":"2042_CR6","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1308\/1478708051649","volume":"87","author":"I Ahmed","year":"2005","unstructured":"Ahmed I, Deakin D, Parsons SL (2005) Appendix mass: do we know how to treat it? Ann R Coll Surg Engl 87(3):191\u2013195","journal-title":"Ann R Coll Surg Engl"},{"issue":"6","key":"2042_CR7","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1016\/j.surg.2009.11.013","volume":"147","author":"C Simillis","year":"2010","unstructured":"Simillis C, Symeonides P, Shorthouse AJ, Tekkis PP (2010) A meta-analysis comparing conservative treatment versus acute appendectomy for complicated appendicitis (abscess or phlegmon). Surgery. 147(6):818\u2013829","journal-title":"Surgery."},{"issue":"9","key":"2042_CR8","doi-asserted-by":"publisher","first-page":"2026","DOI":"10.1007\/s00268-010-0669-z","volume":"34","author":"G Markides","year":"2010","unstructured":"Markides G, Subar D, Riyad K (2010) Laparoscopic versus open appendectomy in adults with complicated appendicitis: systematic review and meta-analysis. World J Surg 34(9):2026\u20132040","journal-title":"World J Surg"},{"issue":"7","key":"2042_CR9","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1007\/BF02235479","volume":"44","author":"D Oliak","year":"2001","unstructured":"Oliak D, Yamini D, Udani VM, Lewis RJ, Arnell T, Vargas H, Stamos MJ (2001) Initial nonoperative management for periappendiceal abscess. Dis Colon Rectum 44(7):936\u2013941","journal-title":"Dis Colon Rectum"},{"key":"2042_CR10","first-page":"CD010168","volume":"2","author":"Y Cheng","year":"2015","unstructured":"Cheng Y, Zhou S, Zhou R, Lu J, Wu S, Xiong X et al (2015) Abdominal drainage to prevent intra-peritoneal abscess after open appendectomy for complicated appendicitis. Cochrane Database Syst Rev 2:CD010168","journal-title":"Cochrane Database Syst Rev"},{"issue":"5","key":"2042_CR11","first-page":"465","volume":"10","author":"A Tekin","year":"2008","unstructured":"Tekin A, Kurto\u011flu HC, Can I, Oztan S (2008) Routine interval appendectomy is unnecessary after conservative treatment of appendiceal mass. Color Dis Off J Assoc Coloproctology Gt Britain Irel 10(5):465\u2013468","journal-title":"Color Dis Off J Assoc Coloproctology Gt Britain Irel"},{"issue":"2","key":"2042_CR12","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.surge.2016.08.002","volume":"15","author":"J Forsyth","year":"2017","unstructured":"Forsyth J, Lasithiotakis K, Peter M (2017) The evolving management of the appendix mass in the era of laparoscopy and interventional radiology. Surgeon. 15(2):109\u2013115","journal-title":"Surgeon."},{"key":"2042_CR13","doi-asserted-by":"crossref","unstructured":"Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ et al (2019) Cochrane handbook for systematic reviews of interventions. Wiley","DOI":"10.1002\/9781119536604"},{"key":"2042_CR14","unstructured":"Prisma (2015) PRISMA: transparent reporting of systematic reviews and meta-analyses. Ottawa Hospital Research Institute and University of Oxford"},{"issue":"1","key":"2042_CR15","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1007\/s00423-017-1646-x","volume":"403","author":"K Goossen","year":"2018","unstructured":"Goossen K, Tenckhoff S, Probst P, Grummich K, Mihaljevic AL, Buechler MW et al (2018) Optimal literature search for systematic reviews in surgery. Langenbeck\u2019s Arch Surg 403(1):119\u2013129","journal-title":"Langenbeck\u2019s Arch Surg"},{"key":"2042_CR16","doi-asserted-by":"publisher","first-page":"d5928","DOI":"10.1136\/bmj.d5928","volume":"343","author":"JPT Higgins","year":"2011","unstructured":"Higgins JPT, Altman DG, G\u00f8tzsche PC, J\u00fcni P, Moher D, Oxman AD et al (2011) The Cochrane Collaboration\u2019s tool for assessing risk of bias in randomised trials. Bmj. 343:d5928","journal-title":"Bmj."},{"key":"2042_CR17","unstructured":"Wells GA, Shea B, O\u2019Connell D, Peterson J, Welch V, Losos M et al (2000) The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses, Oxford"},{"issue":"1","key":"2042_CR18","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/1471-2288-5-13","volume":"5","author":"SP Hozo","year":"2005","unstructured":"Hozo SP, Djulbegovic B, Hozo I (2005) Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol 5(1):13","journal-title":"BMC Med Res Methodol"},{"issue":"7249","key":"2042_CR19","doi-asserted-by":"publisher","first-page":"1574","DOI":"10.1136\/bmj.320.7249.1574","volume":"320","author":"AJ Sutton","year":"2000","unstructured":"Sutton AJ, Duval SJ, Tweedie RL, Abrams KR, Jones DR (2000) Empirical assessment of effect of publication bias on meta-analyses. Bmj. 320(7249):1574\u20131577","journal-title":"Bmj."},{"key":"2042_CR20","unstructured":"Collaboration C (2014) Review manager (RevMan) [computer program]. Version"},{"key":"2042_CR21","first-page":"165","volume":"23","author":"S Kumar","year":"2004","unstructured":"Kumar S, Jain S (2004) Treatment of appendiceal mass: prospective, randomized clinical trial. Indian J Gastroenterol 23:165\u2013167","journal-title":"Indian J Gastroenterol"},{"issue":"6","key":"2042_CR22","doi-asserted-by":"publisher","first-page":"413","DOI":"10.3393\/jksc.2010.26.6.413","volume":"26","author":"J-K Kim","year":"2010","unstructured":"Kim J-K, Ryoo S, Oh H-K, Kim JS, Shin R, Choe EK, Jeong SY, Park KJ (2010) Management of appendicitis presenting with abscess or mass. J Korean Soc Coloproctol 26(6):413","journal-title":"J Korean Soc Coloproctol"},{"issue":"1","key":"2042_CR23","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1016\/j.jpedsurg.2009.10.039","volume":"45","author":"SDS Peter","year":"2010","unstructured":"Peter SDS, Aguayo P, Fraser JD, Keckler SJ, Sharp SW, Leys CM et al (2010) Initial laparoscopic appendectomy versus initial nonoperative management and interval appendectomy for perforated appendicitis with abscess: a prospective, randomized trial. J Pediatr Surg 45(1):236\u2013240","journal-title":"J Pediatr Surg"},{"issue":"6","key":"2042_CR24","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.9738\/INTSURG-D-14-00179.1","volume":"100","author":"Z Demetrashvili","year":"2015","unstructured":"Demetrashvili Z, Kenchadze G, Pipia I, Ekaladze E, Kamkamidze G (2015) Management of appendiceal mass and abscess. An 11-year experience. Int Surg 100(6):1021\u20131025","journal-title":"Int Surg"},{"issue":"7","key":"2042_CR25","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1016\/j.jpedsurg.2017.09.012","volume":"53","author":"S Saluja","year":"2018","unstructured":"Saluja S, Sun T, Mao J, Steigman SA, Oh PS, Yeo HL, Sedrakyan A, Merianos DJ (2018) Early versus late surgical management of complicated appendicitis in children: a statewide database analysis with one-year follow-up. J Pediatr Surg 53(7):1339\u20131344","journal-title":"J Pediatr Surg"},{"issue":"2","key":"2042_CR26","doi-asserted-by":"publisher","first-page":"103","DOI":"10.4174\/astr.2019.97.2.103","volume":"97","author":"JY Kim","year":"2019","unstructured":"Kim JY, Kim JW, Park JH, Kim BC, Yoon SN (2019) Early versus late surgical management for complicated appendicitis in adults: a multicenter propensity score matching study. Ann Surg Treat Res 97(2):103\u2013111","journal-title":"Ann Surg Treat Res"},{"issue":"12","key":"2042_CR27","first-page":"1433","volume":"21","author":"Y Dong","year":"2018","unstructured":"Dong Y, Tan S, Fang Y, Yu W, Li N (2018) Meta-analysis of laparoscopic surgery versus conservative treatment for appendiceal abscess. Zhonghua Wei Chang Wai Ke Za Zhi 21(12):1433\u20131438","journal-title":"Zhonghua Wei Chang Wai Ke Za Zhi"},{"key":"2042_CR28","doi-asserted-by":"crossref","unstructured":"van Amstel P, Sluckin TC, van Amstel T, van der Lee JH, de Vries R, Derikx JP, Bakx R, van Heurn LE, Gorter RR (2020) Management of appendiceal mass and abscess in children; early appendectomy or initial non-operative treatment? A systematic review and meta-analysis. Surgical endoscopy. Jul 24:1\u20136","DOI":"10.1007\/s00464-020-07822-y"},{"key":"2042_CR29","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.amsu.2019.10.016","volume":"48","author":"Z Demetrashvili","year":"2019","unstructured":"Demetrashvili Z, Kenchadze G, Pipia I, Khutsishvili K, Loladze D, Ekaladze E, Merabishvili G, Kamkamidze G (2019) Comparison of treatment methods of appendiceal mass and abscess: a prospective cohort study. Ann Med Surg 48:48\u201352","journal-title":"Ann Med Surg"}],"container-title":["Langenbeck's Archives of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-020-02042-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00423-020-02042-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-020-02042-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,18]],"date-time":"2021-08-18T04:40:03Z","timestamp":1629261603000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00423-020-02042-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,8]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["2042"],"URL":"https:\/\/doi.org\/10.1007\/s00423-020-02042-3","relation":{},"ISSN":["1435-2443","1435-2451"],"issn-type":[{"value":"1435-2443","type":"print"},{"value":"1435-2451","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,8]]},"assertion":[{"value":"21 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}]}}