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Main endpoints were the correlation of intraoperative ICG values to postoperative complications (Comprehensive Complication Index (CCI\u00ae)) at discharge and 90\u00a0days after surgery, and to postoperative liver function.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Median intraoperative R15 (ICG retention rate at 15\u00a0min) correlated significantly with CCI\u00ae at discharge (<jats:italic>p<\/jats:italic>\u2009=\u20090.05) and with CCI\u00ae at 90\u00a0days (<jats:italic>p<\/jats:italic>\u2009=\u20090.0036). Preoperative ICG, volumetry, and scintigraphy did not correlate to postoperative outcome. ROC curve analysis revealed a cutoff value of 11.4 for the intraoperative R15 to predict major complications (Clavien-Dindo\u2009\u2265\u2009III) with 100% sensitivity and 63% specificity. No patient with R15\u2009\u2264\u200911 developed major complications.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This pilot study suggests that intraoperative ICG clearance determines the functional capacity of the future liver remnant more accurately than preoperative tests. This may further reduce the number of postoperative liver failures, even if it means intraoperative abortion of hepatectomy in individual cases.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00423-023-02983-5","type":"journal-article","created":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T23:02:19Z","timestamp":1688511739000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The value of intraoperative dynamic liver function test ICG in predicting postoperative complications in patients undergoing staged hepatectomy: a pilot study"],"prefix":"10.1007","volume":"408","author":[{"given":"Karoline","family":"Horisberger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"R\u00f6ssler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian E.","family":"Oberkofler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitri","family":"Raptis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Petrowsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre-Alain","family":"Clavien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,7,5]]},"reference":[{"issue":"2","key":"2983_CR1","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s00534-008-0017-y","volume":"16","author":"G Garcea","year":"2009","unstructured":"Garcea G, Maddern GJ (2009) Liver failure after major hepatic resection. 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