{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:44:16Z","timestamp":1790232256868,"version":"4.1.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T00:00:00Z","timestamp":1693180800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T00:00:00Z","timestamp":1693180800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100007102","name":"Zagazig University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007102","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Langenbecks Arch Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Most patients with sigmoid volvulus are of old age with multiple comorbidities. So, the risk of surgery for those elderly patients is usually associated with increased rates of morbidity and mortality. Early intervention is required for managing sigmoid volvulus to avoid its serious complications; therefore, early endoscopic untwist of sigmoid colon can be performed followed by endoscopic fixation of sigmoid colon under sedation in this category of the patients to avoid development of high risk surgical complications following surgical fixation of sigmoid colon or sigmoidectomy after initial simple loop colostomy procedure to relieve obstruction.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This prospective randomized controlled clinical trial included all patients who developed acute sigmoid volvulus and were referred to the Zagazig University Hospital Emergency Department between December 2020 and August 2022. The study was prospectively approved by Zagazig University Faculty of Medicine Institutional Review Board (Approval Number: 9989\/23-10-2022) and was retrospectively submitted in <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/clinicaltrials.gov\">http:\/\/clinicaltrials.gov<\/jats:ext-link> in November 2022 (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/clinicaltrials.gov\">http:\/\/clinicaltrials.gov<\/jats:ext-link> ID: NCT05620446). Included eligible patients were simply randomized at a 1:1 ratio to \u201cEndoscopic Group (EG)\u201d or \u201cSurgical Group (SG)\u201d via drawing of sealed envelopes containing computer-generated random numbers prepared by a third party before start of intervention.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Sample size included 18 patients divided into 2 equal groups. (1) Endoscopic group included 9 patients who were subjected to endoscopic untwist of sigmoid colon followed by endoscopic fixation of sigmoid colon under sedation; (2) Surgical group included 9 patients who were subjected to surgical fixation of sigmoid colon or sigmoidectomy after initial simple loop colostomy under general anesthesia. In comparison between both groups, there were statistically significant differences regarding length of hospital stay and procedure time. Unfortunately, there were no statistically significant differences regarding postoperative complications and co-morbidities. Eight patients in the endoscopy group demonstrated excellent quality of life, and one demonstrated good quality of life; unlike the surgical group, there were 3 patients with excellent quality of life, 5 patients with good quality of life, and 1 patient with poor quality of life. So there was statistically significant difference regarding quality of life between both groups. During the 9-month follow-up period, both groups demonstrated no cases of recurrence post-fixation.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Endoscopic management of acute sigmoid volvulus is effective and safe in elderly high risk surgical patients (either in managing the intestinal obstruction caused by volvulus or in definitive treatment of volvulus).<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00423-023-03071-4","type":"journal-article","created":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T02:01:36Z","timestamp":1693188096000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Endoscopic management of acute sigmoid volvulus in high risk surgical elderly patients: a randomized controlled trial"],"prefix":"10.1007","volume":"408","author":[{"given":"Said","family":"Negm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Farag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Shafiq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel","family":"Moursi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr A.","family":"Abdelghani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,8,28]]},"reference":[{"key":"3071_CR1","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1111\/j.1463-1318.2010.02262.x","volume":"12","author":"V Raveenthiran","year":"2010","unstructured":"Raveenthiran V, Madiba TE, Atamanalp SS et al (2010) Volvulus of the sigmoid colon. Colorectal Dis 12:e1\u2013e17","journal-title":"Colorectal Dis"},{"key":"3071_CR2","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1177\/000313481207800331","volume":"78","author":"SB Osiro","year":"2012","unstructured":"Osiro SB, Cunningham D, Shoja MM et al (2012) The twisted colon: a review of sigmoid volvulus. Am Surg 78:271\u2013279","journal-title":"Am Surg"},{"issue":"5","key":"3071_CR3","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1007\/DCR.0b013e31820b8071","volume":"54","author":"AN Gordon-Weeks","year":"2011","unstructured":"Gordon-Weeks AN, Lorenzi B, Lim J, Cristaldi M (2011) Laparoscopic-assisted endoscopic sigmoidopexy: a new surgical option for sigmoid volvulus. Dis Colon Rectum 54(5):645\u2013647. https:\/\/doi.org\/10.1007\/DCR.0b013e31820b8071","journal-title":"Dis Colon Rectum"},{"key":"3071_CR4","doi-asserted-by":"publisher","first-page":"e331","DOI":"10.1055\/s-0032-1309858","volume":"44","author":"J Molina-Infante","year":"2012","unstructured":"Molina-Infante J, Fernandez-Bermejo M, Mateos-Rodriguez JM (2012) Recurrent rectosigmoid volvulus and fatal peritonitis after percutaneousendoscopic sigmoidostomy. Endoscopy 44:e331\u2013e332","journal-title":"Endoscopy"},{"key":"3071_CR5","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1111\/codi.12959","volume":"17","author":"M Bruzzi","year":"2015","unstructured":"Bruzzi M, Lef\u00e8vre JH, Desaint B et al (2015) Management of acute sigmoid volvulus: short- and long-term results. Colorectal Dis 17:922\u2013928","journal-title":"Colorectal Dis"},{"key":"3071_CR6","doi-asserted-by":"publisher","first-page":"18384","DOI":"10.3748\/wjg.v20.i48.18384","volume":"20","author":"AK Ifversen","year":"2014","unstructured":"Ifversen AK, Kjaer DW (2014) More patients should undergo surgery after sigmoid volvulus. World J Gastroenterol 20:18384\u201318389","journal-title":"World J Gastroenterol"},{"key":"3071_CR7","first-page":"806","volume":"23","author":"MA Khan","year":"2013","unstructured":"Khan MA, Ullah S, Beckly D, Oppong FC (2013) Percutaneous endoscopic colostomy (PEC): an effective alternative in high risk patients with recurrent sigmoid volvulus. J Coll Physicians Surg Pak 23:806\u2013808","journal-title":"J Coll Physicians Surg Pak"},{"key":"3071_CR8","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1097\/DCR.0000000000000602","volume":"59","author":"JD Vogel","year":"2016","unstructured":"Vogel JD, Feingold DL, Stewart DB et al (2016) Clinical practice guidelines for colon volvulus and acute colonic pseudo-obstruction. Dis Colon Rectum 59:589\u2013600","journal-title":"Dis Colon Rectum"},{"key":"3071_CR9","doi-asserted-by":"crossref","unstructured":"Chase TJ, Luck J, Harris LS, Bashir G (2017) Conservative management of migrated percutaneous endoscopic colostomy tube. J Surg Case Rep:rjw227","DOI":"10.1093\/jscr\/rjw227"},{"key":"3071_CR10","doi-asserted-by":"crossref","unstructured":"Pinedo G, Kirberg A (2001) Percutaneous endoscopic sigmoidopexy in sigmoid volvulus with T-fasteners. Dis Colon Rectum J (44):1867\u20131869","DOI":"10.1007\/BF02234469"},{"key":"3071_CR11","doi-asserted-by":"publisher","first-page":"16694","DOI":"10.1038\/s41598-021-96357-w","volume":"11","author":"T Kamada","year":"2021","unstructured":"Kamada T, Ohdaira H, Takahashi J et al (2021) Minimally invasive colostomy with endoscopy as a novel technique for creation of a trephine stoma. Sci Rep 11:16694. https:\/\/doi.org\/10.1038\/s41598-021-96357-w","journal-title":"Sci Rep"},{"key":"3071_CR12","unstructured":"M. Clinton Miller, Ph.D, Rebecca G. Knapp: Clinical epidemiology and biostatistics, published by Williams & Wilkins, Maryland: 3rd edition 1992."},{"issue":"4","key":"3071_CR13","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.afju.2015.06.003","volume":"21","author":"V Singh","year":"2015","unstructured":"Singh V, Jhanwar A, Mehrotra S, Sinha RJ (2015) A comparison of quality of life before and after successful repair of genitourinary fistula: Is there improvement across all the domains of WHOQOL-BREF questionnaire? Afr J Urol 21(4):230\u2013234","journal-title":"Afr J Urol"},{"key":"3071_CR14","doi-asserted-by":"publisher","first-page":"5812","DOI":"10.3748\/wjg.v18.i40.5812","volume":"18","author":"S Toebosch","year":"2012","unstructured":"Toebosch S, Tudyka V, Masclee A, Koek G (2012) Treatment of recurrent sigmoid volvulus in Parkinson\u2019s disease by percutaneous endoscopic colostomy. World J Gastroenterol 18:5812\u20135915","journal-title":"World J Gastroenterol"},{"issue":"Suppl 1","key":"3071_CR15","first-page":"40","volume":"11","author":"N Johns","year":"2009","unstructured":"Johns N, Speakman CT, Fellows I (2009) Percutaneous endoscopic colostomy (PEC) technique and audit. Colorectal Dis 11(Suppl 1):40","journal-title":"Colorectal Dis"},{"key":"3071_CR16","volume-title":"Percutaneous endoscopic colostomy (IPG161)","author":"National Institute for Health and Clinical Excellence","year":"2006","unstructured":"National Institute for Health and Clinical Excellence (2006) Percutaneous endoscopic colostomy (IPG161). NICE, London"},{"issue":"3","key":"3071_CR17","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/j.gie.2019.04.246","volume":"90","author":"T Imakita","year":"2019","unstructured":"Imakita T, Suzuki Y, Ohdaira H, Urashima M (2019) Colonscopy- assisted percutaneous sigmoidopexy: a novel , simple , safe , and efficient treatment for inoperable sigmoid volvulus. Gastrointest Endosc 90(3):514\u2013520. https:\/\/doi.org\/10.1016\/j.gie.2019.04.246","journal-title":"Gastrointest Endosc"}],"container-title":["Langenbeck's Archives of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-023-03071-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00423-023-03071-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-023-03071-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T00:11:06Z","timestamp":1705623066000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00423-023-03071-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,28]]},"references-count":17,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["3071"],"URL":"https:\/\/doi.org\/10.1007\/s00423-023-03071-4","relation":{},"ISSN":["1435-2451"],"issn-type":[{"value":"1435-2451","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,28]]},"assertion":[{"value":"6 December 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 August 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was prospectively approved by Zagazig University Faculty of Medicine Institutional Review Board (Approval Number: 9989\/23-10-2022), and was retrospectively submitted in  in November 2022 ( ID: NCT05620446). The study was performed in accordance with the code of ethics of the World Medical Association (Declaration of Helsinki) for studies involving human subjects. Written informed consent was obtained from all participants after explaining to them all the study procedures with its benefits and hazards.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}},{"value":"Obtained.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"338"}}