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Eligible patients were stratified into two groups according to positive or negative PWC. Recurrence-free survival and overall survival were compared between the two groups. Independent factors associated with positive PWC were investigated using multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 284 patients analyzed, all 53 patients with ampullary carcinoma showed negative PWC and these patients were excluded. Among the remaining eligible 231 patients, 41 patients had intrahepatic cholangiocarcinoma, 55 had gall bladder carcinoma, 72 had hilar cholangiocarcinoma, and 63 had distal cholangiocarcinoma. Eleven (4.8%) patients had positive PWC, and 220 (95.2%) had negative PWC. The median recurrence-free survival in the positive and negative PWC groups were 12.0<jats:italic>vs.<\/jats:italic>60.7\u00a0months (<jats:italic>p<\/jats:italic>\u2009=\u20090.005); the median overall survival times were 17.0<jats:italic>vs.<\/jats:italic>60.6\u00a0months (<jats:italic>p<\/jats:italic>\u2009=\u20090.008), respectively. Multivariate analysis revealed that serum carbohydrate antigen 19\u20139 level over 80 U\/mL and multiple lymph node metastasis were independently associated with positive PWC (odds ratio [OR]: 5.84,<jats:italic>p<\/jats:italic>\u2009=\u20090.031; OR: 5.28,<jats:italic>p<\/jats:italic>\u2009=\u20090.021, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with positive PWC exhibited earlier recurrence and shorter survival times compared with those with negative PWC.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00423-024-03233-y","type":"journal-article","created":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T08:02:41Z","timestamp":1705910561000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prognostic impact of peritoneal washing cytology in patients with biliary tract cancer"],"prefix":"10.1007","volume":"409","author":[{"given":"Tatsuaki","family":"Sumiyoshi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichiro","family":"Uemura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuta","family":"Shintakuya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenjiro","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenta","family":"Baba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takumi","family":"Harada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Serikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasutaka","family":"Ishii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Arihiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiaki","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,22]]},"reference":[{"key":"3233_CR1","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1097\/00000658-200110000-00010","volume":"234","author":"WR Jarnagin","year":"2001","unstructured":"Jarnagin WR, Fong Y, DeMatteo RP, Gonen M, Burke EC, Bodniewicz BSJ et al (2001) Staging, resectability, and outcome in 225 patients with hilar cholangiocarcinoma. 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