{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T20:13:32Z","timestamp":1784232812955,"version":"3.55.0"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Langenbecks Arch Surg"],"DOI":"10.1007\/s00423-024-03486-7","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T22:01:50Z","timestamp":1727820110000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Predicting the resolution of hypertension following adrenalectomy in primary aldosteronism: Controversies and unresolved issues a narrative review"],"prefix":"10.1007","volume":"409","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7375-555X","authenticated-orcid":false,"given":"Luigi","family":"Marzano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,1]]},"reference":[{"issue":"4","key":"3486_CR1","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1152\/physrev.00026.2015","volume":"96","author":"M Stowasser","year":"2016","unstructured":"Stowasser M, Gordon RD (2016) Primary aldosteronism: changing definitions and new concepts of physiology and pathophysiology both inside and outside the kidney. Physiol Rev 96(4):1327\u20131384","journal-title":"Physiol Rev"},{"issue":"11","key":"3486_CR2","doi-asserted-by":"publisher","first-page":"2293","DOI":"10.1016\/j.jacc.2006.07.059","volume":"48","author":"GP Rossi","year":"2006","unstructured":"Rossi GP et al (2006) A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients. J Am Coll Cardiol 48(11):2293\u20132300","journal-title":"J Am Coll Cardiol"},{"issue":"14","key":"3486_CR3","doi-asserted-by":"publisher","first-page":"1811","DOI":"10.1016\/j.jacc.2017.01.052","volume":"69","author":"S Monticone","year":"2017","unstructured":"Monticone S et al (2017) Prevalence and clinical manifestations of primary aldosteronism encountered in primary care practice. J Am Coll Cardiol 69(14):1811\u20131820","journal-title":"J Am Coll Cardiol"},{"issue":"7","key":"3486_CR4","doi-asserted-by":"publisher","first-page":"2826","DOI":"10.1210\/jc.2016-1472","volume":"101","author":"SC Kayser","year":"2016","unstructured":"Kayser SC et al (2016) Study heterogeneity and estimation of prevalence of primary aldosteronism: a systematic review and meta-regression analysis. J Clin Endocrinol Metab 101(7):2826\u20132835","journal-title":"J Clin Endocrinol Metab"},{"issue":"9628","key":"3486_CR5","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.1016\/S0140-6736(08)60834-X","volume":"371","author":"S Douma","year":"2008","unstructured":"Douma S et al (2008) Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study. Lancet 371(9628):1921\u20131926","journal-title":"Lancet"},{"issue":"9","key":"3486_CR6","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1097\/HJH.0000000000002441","volume":"38","author":"M Parasiliti-Caprino","year":"2020","unstructured":"Parasiliti-Caprino M et al (2020) Prevalence of primary aldosteronism and association with cardiovascular complications in patients with resistant and refractory hypertension. J Hypertens 38(9):1841\u20131848","journal-title":"J Hypertens"},{"issue":"5","key":"3486_CR7","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.1210\/jc.2015-4061","volume":"101","author":"JW Funder","year":"2016","unstructured":"Funder JW et al (2016) The management of primary aldosteronism: case detection, diagnosis, and treatment: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 101(5):1889\u2013916","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"3486_CR8","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1055\/s-0031-1291318","volume":"44","author":"C Catena","year":"2012","unstructured":"Catena C, Colussi G, Marzano L, Sechi LA (2012) Aldosterone and the heart: from basic research to clinical evidence. Horm Metab Res 44(3):181\u2013187","journal-title":"Horm Metab Res"},{"issue":"1","key":"3486_CR9","doi-asserted-by":"publisher","first-page":"47","DOI":"10.5603\/AH.a2021.0006","volume":"25","author":"L Marzano","year":"2021","unstructured":"Marzano L (2021) Primary aldosteronism and coronary-pulmonary artery fistula: coincidence or causal link? A case report and literature review. Arterial Hypertens 25(1):47\u201352","journal-title":"Arterial Hypertens"},{"key":"3486_CR10","doi-asserted-by":"publisher","DOI":"10.1111\/cen.14918","author":"L Marzano","year":"2023","unstructured":"Marzano L, Kazory A, Husain-Syed F, Ronco C (2023) Prognostic models to predict complete resolution of hypertension after adrenalectomy in primary aldosteronism: a systematic review and meta-analysis. Clin Endocrinol (Oxf). https:\/\/doi.org\/10.1111\/cen.14918","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"3","key":"3486_CR11","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1093\/ajh\/hpu154","volume":"28","author":"L Marzano","year":"2015","unstructured":"Marzano L, Colussi G, Sechi LA, Catena C (2015) Adrenalectomy is comparable with medical treatment for reduction of left ventricular mass in primary aldosteronism: meta-analysis of long-term studies. Am J Hypertens 28(3):312\u2013318","journal-title":"Am J Hypertens"},{"issue":"12","key":"3486_CR12","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1038\/ajh.2010.169","volume":"23","author":"LA Sechi","year":"2010","unstructured":"Sechi LA, Colussi G, Di Fabio A, Catena C (2010) Cardiovascular and renal damage in primary aldosteronism: outcomes after treatment. Am J Hypertens 23(12):1253\u20131260","journal-title":"Am J Hypertens"},{"issue":"1","key":"3486_CR13","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/S2213-8587(17)30319-4","volume":"6","author":"S Monticone","year":"2018","unstructured":"Monticone S et al (2018) Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis. Lancet Diabetes Endocrinol 6(1):41\u201350","journal-title":"Lancet Diabetes Endocrinol"},{"key":"3486_CR14","doi-asserted-by":"publisher","first-page":"100029","DOI":"10.1016\/j.ijchy.2020.100029","volume":"5","author":"GP Rossi","year":"2020","unstructured":"Rossi GP et al (2020) The 2020 Italian society of arterial hypertension (SIIA) practical guidelines for the management of primary aldosteronism. Int J Cardiol Hypertens 5:100029","journal-title":"Int J Cardiol Hypertens"},{"key":"3486_CR15","doi-asserted-by":"publisher","first-page":"916744","DOI":"10.3389\/fendo.2022.916744","volume":"13","author":"TH Puar","year":"2022","unstructured":"Puar TH et al (2022) Treatment of primary aldosteronism and reversal of renin suppression improves left ventricular systolic function. Front Endocrinol (Lausanne) 13:916744","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"6","key":"3486_CR16","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1001\/archsurg.134.6.628","volume":"134","author":"WT Shen","year":"1999","unstructured":"Shen WT et al (1999) Laparoscopic vs open adrenalectomy for the treatment of primary hyperaldosteronism. Arch Surg 134(6):628\u201331","journal-title":"Arch Surg"},{"issue":"4","key":"3486_CR17","doi-asserted-by":"publisher","first-page":"e185842","DOI":"10.1001\/jamasurg.2018.5842","volume":"154","author":"W Vorselaars","year":"2019","unstructured":"Vorselaars W et al (2019) Clinical outcomes after unilateral adrenalectomy for primary aldosteronism. JAMA Surg 154(4):e185842","journal-title":"JAMA Surg"},{"issue":"9","key":"3486_CR18","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1016\/S2213-8587(17)30135-3","volume":"5","author":"TA Williams","year":"2017","unstructured":"Williams TA et al (2017) Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort. Lancet Diabetes Endocrinol 5(9):689\u2013699","journal-title":"Lancet Diabetes Endocrinol"},{"key":"3486_CR19","doi-asserted-by":"publisher","DOI":"10.1038\/s41371-022-00731-8","author":"L Marzano","year":"2022","unstructured":"Marzano L, Husain-Syed F, Reis T, Ronco C, Zanella M (2022) Assessment of performance of stratum-specific likelihood ratios of the aldosteronoma resolution score for predicting hypertension cure after adrenalectomy for primary aldosteronism: a systematic review and meta-analysis. J Hum Hypertens. https:\/\/doi.org\/10.1038\/s41371-022-00731-8","journal-title":"J Hum Hypertens"},{"issue":"3","key":"3486_CR20","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1038\/s41440-023-01554-x","volume":"47","author":"L Marzano","year":"2024","unstructured":"Marzano L, Ronco C (2024) Clinical and biochemical outcomes after adrenalectomy for primary aldosteronism in tertiary and quaternary referral centers: data from SOPRANO study. Hypertens Res 47(3):721\u2013734","journal-title":"Hypertens Res"},{"key":"3486_CR21","doi-asserted-by":"publisher","first-page":"925591","DOI":"10.3389\/fendo.2022.925591","volume":"13","author":"W Manosroi","year":"2022","unstructured":"Manosroi W, Atthakomol P, Phinyo P, Inthaphan P (2022) Predictive factors of clinical success after adrenalectomy in primary aldosteronism: a systematic review and meta-analysis. Front Endocrinol (Lausanne) 13:925591","journal-title":"Front Endocrinol (Lausanne)"},{"key":"3486_CR22","doi-asserted-by":"publisher","first-page":"861581","DOI":"10.3389\/fendo.2022.861581","volume":"13","author":"S Ahmed","year":"2022","unstructured":"Ahmed S, Hundemer GL (2022) Benefits of surgical over medical treatment for unilateral primary aldosteronism. Front Endocrinol (Lausanne) 13:861581","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"6","key":"3486_CR23","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1055\/s-0029-1246185","volume":"42","author":"C Catena","year":"2010","unstructured":"Catena C et al (2010) Mineralocorticoid antagonists treatment versus surgery in primary aldosteronism. Horm Metab Res 42(6):440\u2013445","journal-title":"Horm Metab Res"},{"issue":"12","key":"3486_CR24","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1046\/j.1365-2168.2002.02261.x","volume":"89","author":"M Sywak","year":"2002","unstructured":"Sywak M, Pasieka JL (2002) Long-term follow-up and cost benefit of adrenalectomy in patients with primary hyperaldosteronism. Br J Surg 89(12):1587\u20131593","journal-title":"Br J Surg"},{"issue":"3","key":"3486_CR25","doi-asserted-by":"publisher","first-page":"e1280","DOI":"10.1210\/clinem\/dgad654","volume":"109","author":"S Samnani","year":"2024","unstructured":"Samnani S et al (2024) Time to benefit of surgery vs targeted medical therapy for patients with primary aldosteronism: a meta-analysis. J Clin Endocrinol Metab 109(3):e1280\u2013e1289","journal-title":"J Clin Endocrinol Metab"},{"key":"3486_CR26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2023.11.005","author":"YY Chen","year":"2023","unstructured":"Chen YY et al (2023) The predictors of long-term outcomes after targeted therapy for primary aldosteronism. J Formos Med Assoc. https:\/\/doi.org\/10.1016\/j.jfma.2023.11.005","journal-title":"J Formos Med Assoc"},{"issue":"11","key":"3486_CR27","doi-asserted-by":"publisher","first-page":"2012","DOI":"10.1210\/js.2019-00295","volume":"3","author":"M Morisaki","year":"2019","unstructured":"Morisaki M et al (2019) Predictors of clinical success after surgery for primary aldosteronism in the Japanese nationwide cohort. J Endocr Soc 3(11):2012\u20132022","journal-title":"J Endocr Soc"},{"issue":"3","key":"3486_CR28","first-page":"138","volume":"25","author":"H-T Leung","year":"2021","unstructured":"Leung H-T et al (2021) Unilateral adrenalectomy for aldosterone-producing adenoma in Hong Kong: Outcomes and factors predicting resolution of hypertension. Surg Pract, Original Article 25(3):138\u2013145","journal-title":"Surg Pract, Original Article"},{"issue":"6","key":"3486_CR29","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1097\/SLA.0000000000003200","volume":"272","author":"J Burrello","year":"2020","unstructured":"Burrello J et al (2020) The primary aldosteronism surgical outcome score for the prediction of clinical outcomes after adrenalectomy for unilateral primary aldosteronism. Ann Surg 272(6):1125\u20131132","journal-title":"Ann Surg"},{"issue":"3","key":"3486_CR30","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1097\/SLA.0b013e318165c075","volume":"247","author":"R Zarnegar","year":"2008","unstructured":"Zarnegar R et al (2008) The aldosteronoma resolution score: predicting complete resolution of hypertension after adrenalectomy for aldosteronoma. Ann Surg 247(3):511\u2013518","journal-title":"Ann Surg"},{"issue":"6","key":"3486_CR31","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1016\/j.surg.2014.08.021","volume":"156","author":"H Wachtel","year":"2014","unstructured":"Wachtel H et al (2014) Long-term blood pressure control in patients undergoing adrenalectomy for primary hyperaldosteronism. Surgery 156(6):1394\u2013402 (discussion1402-3)","journal-title":"Surgery"},{"issue":"10","key":"3486_CR32","doi-asserted-by":"publisher","first-page":"2640","DOI":"10.1007\/s00268-014-2612-1","volume":"38","author":"T Utsumi","year":"2014","unstructured":"Utsumi T et al (2014) Development of a novel nomogram to predict hypertension cure after laparoscopic adrenalectomy in patients with primary aldosteronism. World J Surg 38(10):2640\u20132644","journal-title":"World J Surg"},{"issue":"42","key":"3486_CR33","first-page":"3379","volume":"96","author":"XQ He","year":"2016","unstructured":"He XQ et al (2016) A Fisher discriminant model to predict the outcome of postoperative blood pressure in primary aldosteronism. Zhonghua Yi Xue Za Zhi 96(42):3379\u20133383 (in Chinese)","journal-title":"Zhonghua Yi Xue Za Zhi"},{"issue":"12","key":"3486_CR34","doi-asserted-by":"publisher","first-page":"e4382","DOI":"10.1210\/clinem\/dgaa634","volume":"105","author":"Y Yang","year":"2020","unstructured":"Yang Y et al (2020) Nomogram-based preoperative score for predicting clinical outcome in unilateral primary aldosteronism. J Clin Endocrinol Metab 105(12):e4382\u2013e4392","journal-title":"J Clin Endocrinol Metab"},{"key":"3486_CR35","first-page":"102333","volume":"65","author":"DPD Suurd","year":"2021","unstructured":"Suurd DPD et al (2021) A simplified primary aldosteronism surgical outcome score is a useful prediction model when target organ damage is unknown - retrospective cohort study. Ann Med Surg (Lond) 65:102333","journal-title":"Ann Med Surg (Lond)"},{"issue":"12","key":"3486_CR36","doi-asserted-by":"publisher","first-page":"2486","DOI":"10.1097\/HJH.0000000000003284","volume":"40","author":"M Araujo-Castro","year":"2022","unstructured":"Araujo-Castro M et al (2022) Predictive model of hypertension resolution after adrenalectomy in primary aldosteronism: the SPAIN-ALDO score. J Hypertens 40(12):2486\u20132493","journal-title":"J Hypertens"},{"key":"3486_CR37","doi-asserted-by":"publisher","first-page":"e074819","DOI":"10.1136\/bmj-2023-074819","volume":"384","author":"GS Collins","year":"2024","unstructured":"Collins GS et al (2024) Evaluation of clinical prediction models (part 1): from development to external validation. BMJ 384:e074819","journal-title":"BMJ"},{"key":"3486_CR38","doi-asserted-by":"publisher","first-page":"e074820","DOI":"10.1136\/bmj-2023-074820","volume":"384","author":"RD Riley","year":"2024","unstructured":"Riley RD et al (2024) Evaluation of clinical prediction models (part 2): how to undertake an external validation study. BMJ 384:e074820","journal-title":"BMJ"},{"issue":"1","key":"3486_CR39","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1186\/s12874-022-01801-8","volume":"22","author":"MAE Binuya","year":"2022","unstructured":"Binuya MAE, Engelhardt EG, Schats W, Schmidt MK, Steyerberg EW (2022) Methodological guidance for the evaluation and updating of clinical prediction models: a systematic review. BMC Med Res Methodol 22(1):316","journal-title":"BMC Med Res Methodol"},{"issue":"10","key":"3486_CR40","doi-asserted-by":"publisher","first-page":"2459","DOI":"10.1007\/s00268-019-05074-z","volume":"43","author":"W Vorselaars","year":"2019","unstructured":"Vorselaars W et al (2019) Validation of the aldosteronoma resolution score within current clinical practice. World J Surg 43(10):2459\u20132468","journal-title":"World J Surg"},{"issue":"Supplement 1","key":"3486_CR41","doi-asserted-by":"publisher","first-page":"e204","DOI":"10.1097\/01.hjh.0000837520.80434.8b","volume":"40","author":"L Marzano","year":"2022","unstructured":"Marzano L, Husain-Syed F, Reis T, Poletto F, Ronco C, Zanella M (2022) Discrimination, calibration, and stratum-specific likelihood ratios for the aldosteronoma resolution score: a meta-analysis. J Hypertens 40(Supplement 1):e204 (in English)","journal-title":"J Hypertens"},{"key":"3486_CR42","doi-asserted-by":"publisher","first-page":"663096","DOI":"10.3389\/fendo.2021.663096","volume":"12","author":"H Wang","year":"2021","unstructured":"Wang H et al (2021) Surgical outcomes of aldosterone-producing adenoma on the basis of the histopathological findings. Front Endocrinol (Lausanne) 12:663096","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"2","key":"3486_CR43","doi-asserted-by":"publisher","first-page":"369","DOI":"10.3803\/EnM.2022.1391","volume":"37","author":"JH Kim","year":"2022","unstructured":"Kim JH et al (2022) Outcome-based decision-making algorithm for treating patients with primary aldosteronism. Endocrinol Metab (Seoul, Korea) 37(2):369\u2013382","journal-title":"Endocrinol Metab (Seoul, Korea)"},{"issue":"1","key":"3486_CR44","doi-asserted-by":"publisher","first-page":"5781","DOI":"10.1038\/s41598-022-09706-8","volume":"12","author":"H Kaneko","year":"2022","unstructured":"Kaneko H et al (2022) Machine learning-based models for predicting clinical outcomes after surgery in unilateral primary aldosteronism. Sci Rep 12(1):5781","journal-title":"Sci Rep"},{"issue":"12","key":"3486_CR45","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1016\/S2213-8587(21)00210-2","volume":"9","author":"M Reincke","year":"2021","unstructured":"Reincke M, Bancos I, Mulatero P, Scholl UI, Stowasser M, Williams TA (2021) Diagnosis and treatment of primary aldosteronism. Lancet Diabetes Endocrinol 9(12):876\u2013892","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"1","key":"3486_CR46","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1186\/s12902-017-0209-z","volume":"17","author":"Y Zhou","year":"2017","unstructured":"Zhou Y, Zhang M, Ke S, Liu L (2017) Hypertension outcomes of adrenalectomy in patients with primary aldosteronism: a systematic review and meta-analysis. BMC Endocr Disord 17(1):61","journal-title":"BMC Endocr Disord"},{"key":"3486_CR47","doi-asserted-by":"publisher","first-page":"i2416","DOI":"10.1136\/bmj.i2416","volume":"353","author":"JA Damen","year":"2016","unstructured":"Damen JA et al (2016) Prediction models for cardiovascular disease risk in the general population: systematic review. BMJ 353:i2416","journal-title":"BMJ"},{"issue":"2","key":"3486_CR48","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1002\/wjs.12030","volume":"48","author":"L Marzano","year":"2024","unstructured":"Marzano L (2024) Letter to the Editor: Validation of the aldosteronoma resolution score as a predictive resolution score of hypertension after unilateral adrenalectomy for primary aldosteronism in a North-African population. World J Surg 48(2):497\u2013498","journal-title":"World J Surg"},{"issue":"8","key":"3486_CR49","doi-asserted-by":"publisher","first-page":"e2200302","DOI":"10.1002\/bimj.202200302","volume":"65","author":"RD Riley","year":"2023","unstructured":"Riley RD, Collins GS (2023) Stability of clinical prediction models developed using statistical or machine learning methods. Biom J 65(8):e2200302","journal-title":"Biom J"},{"issue":"29","key":"3486_CR50","doi-asserted-by":"publisher","first-page":"1925","DOI":"10.1093\/eurheartj\/ehu207","volume":"35","author":"EW Steyerberg","year":"2014","unstructured":"Steyerberg EW, Vergouwe Y (2014) Towards better clinical prediction models: seven steps for development and an ABCD for validation. Eur Heart J 35(29):1925\u20131931","journal-title":"Eur Heart J"},{"issue":"9","key":"3486_CR51","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1109\/TKDE.2008.239","volume":"21","author":"HHEA Garcia","year":"2009","unstructured":"Garcia HHEA (2009) Learning from imbalanced data. IEEE Trans Knowl Data Eng 21(9):1263\u20131284","journal-title":"IEEE Trans Knowl Data Eng"},{"issue":"12","key":"3486_CR52","doi-asserted-by":"publisher","first-page":"e323","DOI":"10.2196\/jmir.5870","volume":"18","author":"W Luo","year":"2016","unstructured":"Luo W et al (2016) Guidelines for developing and reporting machine learning predictive models in biomedical research: a multidisciplinary view. J Med Internet Res 18(12):e323","journal-title":"J Med Internet Res"},{"issue":"8","key":"3486_CR53","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1093\/jamia\/ocac065","volume":"29","author":"HE Wang","year":"2022","unstructured":"Wang HE et al (2022) A bias evaluation checklist for predictive models and its pilot application for 30-day hospital readmission models. J Am Med Inform Assoc 29(8):1323\u20131333","journal-title":"J Am Med Inform Assoc"},{"issue":"6","key":"3486_CR54","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1016\/j.drudis.2021.02.007","volume":"26","author":"K Chakravarty","year":"2021","unstructured":"Chakravarty K, Antontsev V, Bundey Y, Varshney J (2021) Driving success in personalized medicine through AI-enabled computational modeling. Drug Discov Today 26(6):1459\u20131465","journal-title":"Drug Discov Today"},{"issue":"Suppl 2","key":"3486_CR55","doi-asserted-by":"publisher","first-page":"S135","DOI":"10.1016\/j.jfma.2023.11.005","volume":"123","author":"YY Chen","year":"2024","unstructured":"Chen YY et al (2024) The predictors of long-term outcomes after targeted therapy for primary Aldosteronism. J Formos Med Assoc 123(Suppl 2):S135\u2013S140","journal-title":"J Formos Med Assoc"},{"issue":"8","key":"3486_CR56","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1007\/s12149-023-01851-y","volume":"37","author":"X Ren","year":"2023","unstructured":"Ren X, Cheng G, Wang Z (2023) Advances in the molecular imaging of primary aldosteronism. Ann Nucl Med 37(8):433\u2013441","journal-title":"Ann Nucl Med"},{"issue":"2","key":"3486_CR57","doi-asserted-by":"publisher","first-page":"e1001381","DOI":"10.1371\/journal.pmed.1001381","volume":"10","author":"EW Steyerberg","year":"2013","unstructured":"Steyerberg EW et al (2013) Prognosis research strategy (PROGRESS) 3: prognostic model research. PLoS Med 10(2):e1001381","journal-title":"PLoS Med"},{"key":"3486_CR58","doi-asserted-by":"publisher","first-page":"g7594","DOI":"10.1136\/bmj.g7594","volume":"350","author":"GS Collins","year":"2015","unstructured":"Collins GS, Reitsma JB, Altman DG, Moons KG (2015) Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD statement. BMJ 350:g7594","journal-title":"BMJ"}],"container-title":["Langenbeck's Archives of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-024-03486-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00423-024-03486-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-024-03486-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T23:04:41Z","timestamp":1727823881000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00423-024-03486-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,1]]},"references-count":58,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["3486"],"URL":"https:\/\/doi.org\/10.1007\/s00423-024-03486-7","relation":{},"ISSN":["1435-2451"],"issn-type":[{"value":"1435-2451","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,1]]},"assertion":[{"value":"27 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study is a systematic review of current literature; thus, ethical approval was not needed.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"295"}}