{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T15:40:07Z","timestamp":1746286807614,"version":"3.40.4"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T00:00:00Z","timestamp":1746230400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T00:00:00Z","timestamp":1746230400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100006447","name":"University of Zurich","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006447","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Langenbecks Arch Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Purpose<\/jats:title>\n            <jats:p>Epidemiological studies of traumatic brain injury (TBI) in Switzerland have, to date, poorly investigated sex-related differences in causality and predisposing factors. This study examines differences in sex and age related TBI epidemiology in a high-volume trauma centre intensive care unit (ICU) cohort, aiming to identify potential targets for prevention.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>This retrospective, single centre study includes all consecutive TBI patients admitted to the ICU in a 4-year study period. Patient demographics, comorbidities, co-medication, trauma setting and associated risk behaviour were compared between sexes and age groups (over\/under 65\u00a0years).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>592 patients (73.3% male, 26.7% female) were included. The leading cause of TBI was falls (52.4%), followed by road traffic accidents (RTA) (35.8%). Overall, men were more likely to suffer from a road traffic accident, while women were more likely to suffer a low energy fall. No differences in injury severity and comorbidities between sexes were observed. Young patients most likely suffered from a RTA while older patients from a low energy fall irrespective of sex. Both sexes portrayed risk associated behaviors with higher rates of alcohol intoxication in males, while females were less likely to wear a helmet in two-wheeled RTAs.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>We conclude that sex- and age-related epidemiologic differences in TBI exist. Our results suggest that sex and age-specific prevention measures might be advisable for optimal mitigation of TBI and its sequelae.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00423-025-03720-w","type":"journal-article","created":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T02:46:44Z","timestamp":1746240404000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sex and age-related implications for preventive measures of intensive care admitted traumatic brain injury patients in Switzerland: an observational study"],"prefix":"10.1007","volume":"410","author":[{"given":"Juliane","family":"Fleischer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna","family":"Brandi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Teuber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Fl\u00fcckiger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan Y.","family":"B\u00f6gli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Unseld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,3]]},"reference":[{"issue":"7","key":"3720_CR1","doi-asserted-by":"publisher","first-page":"e1002331","DOI":"10.1371\/journal.pmed.1002331","volume":"14","author":"M Majdan","year":"2017","unstructured":"Majdan M, Plancikova D, Maas A, Polinder S, Feigin V, Theadom A et al (2017) Years of life lost due to traumatic brain injury in Europe: a cross-sectional analysis of 16 countries. PLoS Med 14(7):e1002331","journal-title":"PLoS Med"},{"issue":"10","key":"3720_CR2","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1089\/neu.2015.4126","volume":"38","author":"A Brazinova","year":"2021","unstructured":"Brazinova A, Rehorcikova V, Taylor MS, Buckova V, Majdan M, Psota M et al (2021) Epidemiology of traumatic brain injury in Europe: a living systematic review. J Neurotrauma 38(10):1411\u20131440","journal-title":"J Neurotrauma"},{"issue":"8","key":"3720_CR3","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1001\/jamaneurol.2021.2043","volume":"78","author":"MA McCrea","year":"2021","unstructured":"McCrea MA, Giacino JT, Barber J, Temkin NR, Nelson LD, Levin HS et al (2021) Functional outcomes over the first year after moderate to severe traumatic brain injury in the prospective Longitudinal TRACK-TBI Study. JAMA Neurology 78(8):982\u2013992","journal-title":"JAMA Neurology"},{"issue":"6","key":"3720_CR4","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1017\/cjn.2016.290","volume":"43","author":"R Nguyen","year":"2016","unstructured":"Nguyen R, Fiest KM, McChesney J, Kwon CS, Jette N, Frolkis AD et al (2016) The international incidence of traumatic brain injury: a systematic review and meta-analysis. Can J Neurol Sci 43(6):774\u2013785","journal-title":"Can J Neurol Sci"},{"key":"3720_CR5","unstructured":"Alexis B, Peterson KET, Zhou H (2020) Surveilance Report of Traumatic Brain Injury-related Deaths by Age Group, Sex, and Mechanism of Injury-United States, 2018 and 2019. Centers for Disease control and Prevention, U.S. Department of Health and Human Services."},{"issue":"11","key":"3720_CR6","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1016\/S1474-4422(22)00309-X","volume":"21","author":"AIR Maas","year":"2022","unstructured":"Maas AIR, Menon DK, Manley GT, Abrams M, \u00c5kerlund C, Andelic N et al (2022) Traumatic brain injury: progress and challenges in prevention, clinical care, and research. Lancet Neurol 21(11):1004\u20131060","journal-title":"Lancet Neurol"},{"issue":"12","key":"3720_CR7","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1038\/s41582-018-0091-y","volume":"14","author":"T Mollayeva","year":"2018","unstructured":"Mollayeva T, Mollayeva S, Colantonio A (2018) Traumatic brain injury: sex, gender and intersecting vulnerabilities. Nat Rev Neurol 14(12):711\u2013722","journal-title":"Nat Rev Neurol"},{"issue":"2 Suppl","key":"3720_CR8","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1016\/j.apmr.2015.12.002","volume":"97","author":"A Colantonio","year":"2016","unstructured":"Colantonio A (2016) Sex, gender, and traumatic brain injury: a commentary. Arch Phys Med Rehabil 97(2 Suppl):S1-4","journal-title":"Arch Phys Med Rehabil"},{"issue":"10","key":"3720_CR9","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1136\/oemed-2014-102097","volume":"71","author":"VC Chang","year":"2014","unstructured":"Chang VC, Ruseckaite R, Collie A, Colantonio A (2014) Examining the epidemiology of work-related traumatic brain injury through a sex\/gender lens: analysis of workers\u2019 compensation claims in Victoria. Australia Occup Environ Med 71(10):695\u2013703","journal-title":"Australia Occup Environ Med"},{"key":"3720_CR10","doi-asserted-by":"crossref","unstructured":"Peeters W, van den Brande R, Polinder S, Brazinova A, Steyerberg EW, Lingsma HF, et al. (2015). Epidemiology of traumatic brain injury in Europe. Acta Neurochir (Wien).157(10):1683\u201396.","DOI":"10.1007\/s00701-015-2512-7"},{"issue":"5","key":"3720_CR11","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1089\/neu.2010.1488","volume":"28","author":"KA Hartholt","year":"2011","unstructured":"Hartholt KA, Van Lieshout EM, Polinder S, Panneman MJ, Van der Cammen TJ, Patka P (2011) Rapid increase in hospitalizations resulting from fall-related traumatic head injury in older adults in The Netherlands 1986\u20132008. J Neurotrauma 28(5):739\u2013744","journal-title":"J Neurotrauma"},{"key":"3720_CR12","unstructured":"UNDP (2022) Human development index ranking. Available from: https:\/\/hdr.undp.org\/data-center\/country-insights#\/ranks. Accessed 30 Mar 2023"},{"key":"3720_CR13","unstructured":"Forum WE (2022) Global Gender Gap Report 2022. Geneva, Switzerland: World Economic Forum. July 2022."},{"issue":"23\u201324","key":"3720_CR14","first-page":"327","volume":"138","author":"E von Elm","year":"2008","unstructured":"von Elm E, Osterwalder JJ, Graber C, Schoettker P, Stocker R, Zangger P et al (2008) Severe traumatic brain injury in Switzerland - feasibility and first results of a cohort study. Swiss Med Wkly 138(23\u201324):327\u2013334","journal-title":"Swiss Med Wkly"},{"issue":"23","key":"3720_CR15","doi-asserted-by":"publisher","first-page":"1934","DOI":"10.1089\/neu.2013.2955","volume":"30","author":"B Walder","year":"2013","unstructured":"Walder B, Haller G, Rebetez MM, Delhumeau C, Bottequin E, Schoettker P et al (2013) Severe traumatic brain injury in a high-income country: an epidemiological study. J Neurotrauma 30(23):1934\u20131942","journal-title":"J Neurotrauma"},{"issue":"1","key":"3720_CR16","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3109\/09638289209166422","volume":"14","author":"JM Annoni","year":"1992","unstructured":"Annoni JM, Beer S, Kesselring J (1992) Severe traumatic brain injury\u2013epidemiology and outcome after 3 years. Disabil Rehabil 14(1):23\u201326","journal-title":"Disabil Rehabil"},{"key":"3720_CR17","first-page":"w14177","volume":"145","author":"CS Haller","year":"2015","unstructured":"Haller CS, Walder B (2015) Severe neurotrauma in Switzerland: have short-term outcomes improved? Swiss Med Wkly 145:w14177","journal-title":"Swiss Med Wkly"},{"key":"3720_CR18","doi-asserted-by":"publisher","first-page":"1095009","DOI":"10.3389\/fneur.2023.1095009","volume":"14","author":"G Brandi","year":"2023","unstructured":"Brandi G, Gambon-Mair A, Berther LS, B\u00f6gli SY, Unseld S (2023) Sex-related differences in extracranial complications in patients with traumatic brain injury. Front Neurol 14:1095009","journal-title":"Front Neurol"},{"key":"3720_CR19","doi-asserted-by":"crossref","unstructured":"Taksler GB, Hu B, DeGrandis F, Jr, Montori VM, Fagerlin A, Nagykaldi Z, et al (2021) Effect of Individualized Preventive Care Recommendations vs Usual Care on Patient Interest and Use of Recommendations: A Pilot Randomized Clinical Trial. JAMA Network Open 4(11):e2131455-e","DOI":"10.1001\/jamanetworkopen.2021.31455"},{"key":"3720_CR20","doi-asserted-by":"crossref","unstructured":"Menon DK, Schwab K, Wright DW, Maas AI, Demographics, Clinical Assessment Working Group of the I, et al (2010). Position statement: definition of traumatic brain injury. Arch Phys Med Rehabil 91(11):1637\u201340","DOI":"10.1016\/j.apmr.2010.05.017"},{"issue":"1","key":"3720_CR21","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1227\/NEU.0000000000001432","volume":"80","author":"N Carney","year":"2017","unstructured":"Carney N, Totten AM, O\u2019Reilly C, Ullman JS, Hawryluk GW, Bell MJ et al (2017) Guidelines for the management of severe traumatic brain injury fourth edition. Neurosurgery 80(1):6\u201315","journal-title":"Neurosurgery"},{"key":"3720_CR22","doi-asserted-by":"publisher","first-page":"103208","DOI":"10.1016\/j.jbi.2019.103208","volume":"95","author":"PA Harris","year":"2019","unstructured":"Harris PA, Taylor R, Minor BL, Elliott V, Fernandez M, O\u2019Neal L et al (2019) The REDCap consortium: building an international community of software platform partners. J Biomed Inform 95:103208","journal-title":"J Biomed Inform"},{"issue":"2","key":"3720_CR23","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","volume":"42","author":"PA Harris","year":"2009","unstructured":"Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG (2009) Research electronic data capture (REDCap)\u2013a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 42(2):377\u2013381","journal-title":"J Biomed Inform"},{"issue":"11","key":"3720_CR24","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1016\/0895-4356(94)90129-5","volume":"47","author":"M Charlson","year":"1994","unstructured":"Charlson M, Szatrowski TP, Peterson J, Gold J (1994) Validation of a combined comorbidity index. J Clin Epidemiol 47(11):1245\u20131251","journal-title":"J Clin Epidemiol"},{"issue":"5","key":"3720_CR25","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1503\/cmaj.050051","volume":"173","author":"K Rockwood","year":"2005","unstructured":"Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I et al (2005) A global clinical measure of fitness and frailty in elderly people. CMAJ 173(5):489\u2013495","journal-title":"CMAJ"},{"issue":"6","key":"3720_CR26","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1016\/1047-2797(95)00059-3","volume":"5","author":"S Linn","year":"1995","unstructured":"Linn S (1995) The injury severity score\u2013importance and uses. Ann Epidemiol 5(6):440\u2013446","journal-title":"Ann Epidemiol"},{"issue":"1","key":"3720_CR27","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.injury.2015.07.003","volume":"47","author":"CS Palmer","year":"2016","unstructured":"Palmer CS, Gabbe BJ, Cameron PA (2016) Defining major trauma using the 2008 Abbreviated Injury Scale. Injury 47(1):109\u2013115","journal-title":"Injury"},{"issue":"53","key":"3720_CR28","first-page":"2117","volume":"121","author":"CJ Avezaat","year":"1977","unstructured":"Avezaat CJ, Braakman R, Maas AI (1977) A scoring device for the level of consciousness: the Glasgow \u201ccoma\u201d scale. Ned Tijdschr Geneeskd 121(53):2117\u20132121","journal-title":"Ned Tijdschr Geneeskd"},{"issue":"7872","key":"3720_CR29","first-page":"81","volume":"2","author":"G Teasdale","year":"1974","unstructured":"Teasdale G, Jennett B (1974) Assessment of coma and impaired consciousness. A Practical Scale Lancet 2(7872):81\u201384","journal-title":"A Practical Scale Lancet"},{"issue":"8","key":"3720_CR30","first-page":"822","volume":"82","author":"BM Cesana","year":"2016","unstructured":"Cesana BM, Cavaliere F (2016) Basics to perform and present statistical analyses in scientific biomedical reports Part 1. Minerva Anestesiol 82(8):822\u2013826","journal-title":"Minerva Anestesiol"},{"key":"3720_CR31","unstructured":"Cesana BM, Cavaliere F (2016) Basics to perform and present statistical analyses in scientific biomedical reports. Part 2. Minerva Anestesiol 82(9):935\u20139"},{"issue":"10","key":"3720_CR32","first-page":"1032","volume":"82","author":"BM Cesana","year":"2016","unstructured":"Cesana BM, Cavaliere F (2016) Basics to perform and present statistical analyses in scientific biomedical reports Part 3. Minerva Anestesiol 82(10):1032\u20131035","journal-title":"Minerva Anestesiol"},{"issue":"1\u20132","key":"3720_CR33","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/s00508-006-0761-4","volume":"119","author":"A Rosso","year":"2007","unstructured":"Rosso A, Brazinova A, Janciak I, Wilbacher I, Rusnak M, Mauritz W (2007) Severe traumatic brain injury in Austria II: epidemiology of hospital admissions. Wien Klin Wochenschr 119(1\u20132):29\u201334","journal-title":"Wien Klin Wochenschr"},{"key":"3720_CR34","doi-asserted-by":"crossref","unstructured":"G\u00f3mez PA, Casta\u00f1o-Leon AM, de-la-Cruz J, Lora D, Lagares A (2014) Trends in epidemiological and clinical characteristics in severe traumatic brain injury: analysis of the past 25 years of a single centre data base. Neurocirugia (Astur) 25(5):199\u2013210","DOI":"10.1016\/j.neucir.2014.05.001"},{"issue":"6","key":"3720_CR35","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1007\/s10900-021-01005-z","volume":"46","author":"N Kureshi","year":"2021","unstructured":"Kureshi N, Erdogan M, Thibault-Halman G, Fenerty L, Green RS, Clarke DB (2021) Long-term trends in the epidemiology of major traumatic brain injury. J Community Health 46(6):1197\u20131203","journal-title":"J Community Health"},{"issue":"11","key":"3720_CR36","doi-asserted-by":"publisher","first-page":"1821","DOI":"10.1016\/j.injury.2012.07.188","volume":"43","author":"LA Harvey","year":"2012","unstructured":"Harvey LA, Close JC (2012) Traumatic brain injury in older adults: characteristics, causes and consequences. Injury 43(11):1821\u20131826","journal-title":"Injury"},{"issue":"23","key":"3720_CR37","doi-asserted-by":"publisher","first-page":"3315","DOI":"10.1089\/neu.2021.0116","volume":"38","author":"A Mikolic","year":"2021","unstructured":"Mikolic A, Groeniger JO, Zeldovich M, Wilson L, van Lennep JR, van Klaveren D et al (2021) Explaining Outcome Differences between Men and Women following mild traumatic brain injury. J Neurotrauma 38(23):3315\u20133331","journal-title":"J Neurotrauma"},{"key":"3720_CR38","first-page":"219","volume":"7","author":"R van den Bos","year":"2013","unstructured":"van den Bos R, Taris R, Scheppink B, de Haan L, Verster JC (2013) Salivary cortisol and alpha-amylase levels during an assessment procedure correlate differently with risk-taking measures in male and female police recruits. Front Behav Neurosci 7:219","journal-title":"Front Behav Neurosci"},{"issue":"3","key":"3720_CR39","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1177\/0706743716632512","volume":"61","author":"SK Blaine","year":"2016","unstructured":"Blaine SK, Milivojevic V, Fox H, Sinha R (2016) Alcohol effects on stress pathways: impact on craving and relapse risk. The Canadian Journal of Psychiatry 61(3):145\u2013153","journal-title":"The Canadian Journal of Psychiatry"},{"key":"3720_CR40","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.psyneuen.2017.07.240","volume":"84","author":"LM Kluen","year":"2017","unstructured":"Kluen LM, Agorastos A, Wiedemann K, Schwabe L (2017) Cortisol boosts risky decision-making behavior in men but not in women. Psychoneuroendocrinology 84:181\u2013189","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"3720_CR41","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1111\/j.1532-5415.1999.tb01898.x","volume":"47","author":"RM Leipzig","year":"1999","unstructured":"Leipzig RM, Cumming RG, Tinetti ME (1999) Drugs and falls in older people: a systematic review and meta-analysis: I. Psychotropic drugs J Am Geriatr Soc 47(1):30\u201339","journal-title":"Psychotropic drugs J Am Geriatr Soc"},{"issue":"1","key":"3720_CR42","doi-asserted-by":"publisher","first-page":"e187381","DOI":"10.1001\/jamanetworkopen.2018.7381","volume":"2","author":"TK Trivedi","year":"2019","unstructured":"Trivedi TK, Liu C, Antonio ALM, Wheaton N, Kreger V, Yap A et al (2019) Injuries associated with standing electric scooter use. JAMA Netw Open 2(1):e187381","journal-title":"JAMA Netw Open"},{"issue":"5","key":"3720_CR43","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1136\/injuryprev-2020-044085","volume":"27","author":"M Toofany","year":"2021","unstructured":"Toofany M, Mohsenian S, Shum LK, Chan H, Brubacher JR (2021) Injury patterns and circumstances associated with electric scooter collisions: a scoping review. Inj Prev 27(5):490\u2013499","journal-title":"Inj Prev"},{"issue":"15","key":"3720_CR44","doi-asserted-by":"publisher","first-page":"3359","DOI":"10.3390\/jcm10153359","volume":"10","author":"E Sporri","year":"2021","unstructured":"Sporri E, Halvachizadeh S, Gamble JG, Berk T, Allemann F, Pape HC et al (2021) Comparison of injury patterns between electric bicycle, bicycle and motorcycle accidents. J Clin Med 10(15):3359","journal-title":"J Clin Med"},{"key":"3720_CR45","doi-asserted-by":"publisher","first-page":"106430","DOI":"10.1016\/j.aap.2021.106430","volume":"163","author":"GF Serra","year":"2021","unstructured":"Serra GF, Fernandes FAO, Noronha E, de Sousa RJA (2021) Head protection in electric micromobility: a critical review, recommendations, and future trends. Accid Anal Prev 163:106430","journal-title":"Accid Anal Prev"},{"issue":"2","key":"3720_CR46","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1136\/ip-2022-044722","volume":"29","author":"RA Clough","year":"2023","unstructured":"Clough RA, Platt E, Cole E, Wilson M, Aylwin C (2023) Major trauma among E-Scooter and bicycle users: a nationwide cohort study. Inj Prev 29(2):121\u2013125","journal-title":"Inj Prev"},{"issue":"2","key":"3720_CR47","first-page":"135","volume":"66","author":"K Bascones","year":"2022","unstructured":"Bascones K, Maio M\u00e9ndez TE, Ya\u00f1ezSiller FA (2022) E-scooter accidents: a new epidemic. Rev Esp Cir Ortop Traumatol 66(2):135\u2013142","journal-title":"Rev Esp Cir Ortop Traumatol"},{"issue":"1","key":"3720_CR48","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s13049-022-01042-0","volume":"30","author":"H Vasara","year":"2022","unstructured":"Vasara H, Toppari L, Harjola VP, Virtanen K, Castr\u00e9n M, Kobylin A (2022) Characteristics and costs of electric scooter injuries in Helsinki: a retrospective cohort study. Scand J Trauma Resusc Emerg Med 30(1):57","journal-title":"Scand J Trauma Resusc Emerg Med"},{"key":"3720_CR49","doi-asserted-by":"publisher","first-page":"106427","DOI":"10.1016\/j.aap.2021.106427","volume":"163","author":"C Gioldasis","year":"2021","unstructured":"Gioldasis C, Christoforou Z, Seidowsky R (2021) Risk-taking behaviors of e-scooter users: a survey in Paris. Accid Anal Prev 163:106427","journal-title":"Accid Anal Prev"},{"key":"3720_CR50","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1186\/s12877-015-0155-4","volume":"15","author":"C de Labra","year":"2015","unstructured":"de Labra C, Guimaraes-Pinheiro C, Maseda A, Lorenzo T, Mill\u00e1n-Calenti JC (2015) Effects of physical exercise interventions in frail older adults: a systematic review of randomized controlled trials. BMC Geriatr 15:154","journal-title":"BMC Geriatr"},{"issue":"1","key":"3720_CR51","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1111\/j.1532-5415.1999.tb01899.x","volume":"47","author":"RM Leipzig","year":"1999","unstructured":"Leipzig RM, Cumming RG, Tinetti ME (1999) Drugs and falls in older people: a systematic review and meta-analysis: II. Cardiac and analgesic drugs. J Am Geriatr Soc. 47(1):40\u201350","journal-title":"J Am Geriatr Soc."},{"issue":"11","key":"3720_CR52","doi-asserted-by":"publisher","first-page":"842","DOI":"10.3390\/brainsci10110842","volume":"10","author":"N Eibinger","year":"2020","unstructured":"Eibinger N, Halvachizadeh S, Hallmann B, Seibert FJ, Puchwein P, Berk T et al (2020) Is the Regular Intake of Anticoagulative Agents an Independent Risk Factor for the Severity of Traumatic Brain Injuries in Geriatric Patients? A Retrospective Analysis of 10,559 Patients from the TraumaRegister DGU(\u00ae). Brain Sci. 10(11):842","journal-title":"Brain Sci."}],"container-title":["Langenbeck's Archives of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-025-03720-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00423-025-03720-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00423-025-03720-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T15:02:41Z","timestamp":1746284561000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00423-025-03720-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,3]]},"references-count":52,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3720"],"URL":"https:\/\/doi.org\/10.1007\/s00423-025-03720-w","relation":{},"ISSN":["1435-2451"],"issn-type":[{"type":"electronic","value":"1435-2451"}],"subject":[],"published":{"date-parts":[[2025,5,3]]},"assertion":[{"value":"21 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The cantonal ethics committee of Zurich headed by Prof. Dr. med. Konrad E. Bloch retrospectively approved the study (study number: 2023\u201301165) on the 15 th September 2023. The study has been conducted in accordance with the ethical principles of the Declaration of Helsinki in 1964. Documented consent was provided by all patients or their proxy who were included in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"150"}}