{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T21:35:15Z","timestamp":1698788115820},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2008,1,5]],"date-time":"2008-01-05T00:00:00Z","timestamp":1199491200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pflugers Arch - Eur J Physiol"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1007\/s00424-007-0437-6","type":"journal-article","created":{"date-parts":[[2008,1,4]],"date-time":"2008-01-04T09:59:36Z","timestamp":1199440776000},"page":"467-477","source":"Crossref","is-referenced-by-count":4,"title":["Increased sinusoidal resistance is responsible for the basal state and endothelin-induced venoconstriction in perfused cirrhotic rat liver"],"prefix":"10.1007","volume":"456","author":[{"given":"Toshishige","family":"Shibamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiaki","family":"Kamikado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shozo","family":"Koyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,1,5]]},"reference":[{"key":"437_CR1","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/1056-8719(95)00095-X","volume":"34","author":"B Alexander","year":"1995","unstructured":"Alexander B, Aslam M, Benjamin IS (1995) Hepatic function during prolonged isolated rat liver perfusion using a new miniaturized perfusion circuit. J Pharmacol Toxicol Methods 34:203\u2013210","journal-title":"J Pharmacol Toxicol Methods"},{"key":"437_CR2","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/0016-5085(93)90360-O","volume":"104","author":"M Asbert","year":"1993","unstructured":"Asbert M, Gines A, Gines P, Jimenez W, Claria J et al (1993) Circulating levels of endothelin in cirrhosis. Gastroenterology 104:1485\u20131491","journal-title":"Gastroenterology"},{"key":"437_CR3","first-page":"283","volume":"244","author":"F Ballet","year":"1988","unstructured":"Ballet F, Chretien Y, Rey C, Poupon R (1988) Differential response of normal and cirrhotic liver to vasoactive agents. A study in the isolated perfused rat liver. J Pharmacol Exp Ther 244:283\u2013289","journal-title":"A study in the isolated perfused rat liver. J Pharmacol Exp Ther"},{"key":"437_CR4","first-page":"G143","volume":"267","author":"M Bauer","year":"1994","unstructured":"Bauer M, Zhang JX, Bauer I, Clemens MG (1994) ET-1 induced alterations of hepatic microcirculation: sinusoidal and extrasinusoidal sites of action. Am J Physiol 267:G143\u2013G149","journal-title":"Am J Physiol"},{"key":"437_CR5","first-page":"1565","volume":"22","author":"M Bauer","year":"1995","unstructured":"Bauer M, Paquette NC, Zhang JX, Bauer I, Pannen BH et al (1995) Chronic ethanol consumption increases hepatic sinusoidal contractile response to endothelin-1 in the rat. Hepatology 22:1565\u20131576","journal-title":"Hepatology"},{"key":"437_CR6","first-page":"1047","volume":"13","author":"S Beker","year":"1968","unstructured":"Beker S, Valencia-Parparcen J (1968) Portal hypertension syndrome. A comparative analysis of bilhazial fibrosis and hepatic cirrhosis. Am J Dig Dis 13:1047\u20131054","journal-title":"A comparative analysis of bilhazial fibrosis and hepatic cirrhosis. Am J Dig Dis"},{"key":"437_CR7","first-page":"887","volume":"40","author":"PS Bhathal","year":"1985","unstructured":"Bhathal PS, Grossman HJ (1985) Reduction of the increased portal vascular resistance of the isolated perfused cirrhotic rat liver by vasodilators. J Hepatol 40:887\u2013890","journal-title":"J Hepatol"},{"key":"437_CR8","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/hep.1840020505","volume":"2","author":"LM Blendis","year":"1982","unstructured":"Blendis LM, Orrego H, Crossley IR, Blake JE, Medline A (1982) The role of hepatocyte enlargement in hepatic pressure in cirrhotic and noncirrhotic alchololic liver disease. Hepatology 2:539\u2013546","journal-title":"Hepatology"},{"key":"437_CR9","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1002\/hep.510290615","volume":"29","author":"LD DeLeve","year":"1999","unstructured":"DeLeve LD, McCuskey RS, Wang X, Hu L, McCuskey MK et al (1999) Characterization of a reproducible rat model of hepatic veno-occlusive disease. Hepatology 29:1779\u20131791","journal-title":"Hepatology"},{"key":"437_CR10","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/j.1440-1746.1997.tb00427.x","volume":"12","author":"AJ Elliot","year":"1997","unstructured":"Elliot AJ, Vo LT, Grossman VL, Bhathal PS, Grossman HJ (1997) Endothelin-induced vasoconstriction in isolated perfused liver preparations from normal and cirrhotic rats. J Gastroenterol Hepatol 12:314\u2013318","journal-title":"J Gastroenterol Hepatol"},{"key":"437_CR11","first-page":"1828","volume":"328","author":"SL Friedman","year":"1993","unstructured":"Friedman SL (1993) Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. N Engl J Med 328:1828\u20131835","journal-title":"The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. N Engl J Med"},{"key":"437_CR12","unstructured":"Greenway CV, Lautt WW (1989) Hepatic circulation. In: Handbook of Physiology. The Gastrointestinal System. Motility & Circulation. Bethesda, MD: Am Physiol Soc, sect. 6, vol. I, pt. 2, chapt. 41, p. 1519\u201364"},{"key":"437_CR13","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/0016-5085(94)90233-X","volume":"107","author":"M Hartleb","year":"1994","unstructured":"Hartleb M, Moreau R, Cailmail S, Gaudin C, Lebrec D (1994) Vascular hyporesponsiveness to endothelin 1 in rats with cirrhosis. Gastroenterology 107:1085\u20131093","journal-title":"Gastroenterology"},{"key":"437_CR14","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S0016-5085(99)70136-8","volume":"116","author":"J Heller","year":"1999","unstructured":"Heller J, Schepke M, Gehnen N, Molderings GJ, Muller A et al (1999) Altered adrenergic responsiveness of endothelium-denuded hepatic arteries and portal veins in patients with cirrhosis. Gastroenterology 116:387\u2013393","journal-title":"Gastroenterology"},{"key":"437_CR15","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1159\/000179181","volume":"16","author":"Y Ito","year":"1996","unstructured":"Ito Y, Katori M, Majima M, Kakita A (1996) Constriction of mouse hepatic venules and sinusoids by endothelins through ETB receptor subtype. Int J Microcirc Clin Exp 16:250\u2013258","journal-title":"Int J Microcirc Clin Exp"},{"key":"437_CR16","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/sj.mn.7800208","volume":"10","author":"Y Ito","year":"2003","unstructured":"Ito Y, Bethea NW, Baker GL, McCuskey MK, Urbaschek R et al (2003) Hepatic microcirculatory dysfunction during cholestatic liver injury in rats. Microcirculation 10:421\u2013432","journal-title":"Microcirculation"},{"key":"437_CR17","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1002\/hep.1840140645","volume":"14","author":"G Jacob","year":"1991","unstructured":"Jacob G, Bishara B, Lee SS, Hilzenart N, Bomzon A (1991) Cardiovascular responses to serotonin in experimental liver disease. Hepatology 14:1235\u20131242","journal-title":"Hepatology"},{"key":"437_CR18","doi-asserted-by":"crossref","first-page":"H121","DOI":"10.1152\/ajpheart.01136.2002","volume":"286","author":"C Kamikado","year":"2004","unstructured":"Kamikado C, Shibamoto T, Hongo M, Koyama S (2004) Effects of Hct and norepinephrine on segmental vascular resistance distribution in isolated perfused rat livers. Am J Physiol Heart Circ Physiol 286:H121\u2013H130","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"437_CR19","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1002\/hep.510270315","volume":"27","author":"K Kaneda","year":"1998","unstructured":"Kaneda K, Ekataksin W, Sogawa M, Matsumura A, Cho A et al (1998) Endothelin-1-induced vasoconstriction causes a significant increase in portal pressure of rat liver: localized constrictive effect on the distal segment of preterminal portal venules as revealed by light and electron microscopy and reconstruction. Hepatology 27:735\u2013747","journal-title":"Hepatology"},{"key":"437_CR20","first-page":"815","volume":"213","author":"N Kawada","year":"1993","unstructured":"Kawada N, Tran-Thi T, Klein H, Decker K (1993) The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus. Eur J Biochem 213:815\u2013823","journal-title":"Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus. Eur J Biochem"},{"key":"437_CR21","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0168-8278(00)80188-9","volume":"32","author":"H Kojima","year":"2000","unstructured":"Kojima H, Yamao J, Tsujimoto T, Uemura M, Takaya A et al (2000) Mixed endothelin receptor antagonist, SB209670, decreases portal pressure in biliary cirrhotic rats in vivo by reducing portal venous system resistance. J Hepatol 32:43\u201350","journal-title":"J Hepatol"},{"key":"437_CR22","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S0168-8278(01)00045-9","volume":"34","author":"H Kojima","year":"2001","unstructured":"Kojima H, Sakurai S, Kuriyama S, Yoshiji H, Imazu H et al (2001) Endothelin-1 plays a major role in portal hypertension of biliary cirrhotic rats through endothelin receptor subtype B together with subtype A in vivo. J Hepatol 34:805\u2013811","journal-title":"J Hepatol"},{"key":"437_CR23","first-page":"305","volume":"65","author":"J Kountouras","year":"1984","unstructured":"Kountouras J, Billing BH, Scheuer PJ (1984) Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat. Br J Exp Pathol 65:305\u2013311","journal-title":"Br J Exp Pathol"},{"key":"437_CR24","first-page":"1666","volume":"22","author":"G Laffi","year":"1995","unstructured":"Laffi G, Foschi M, Masini E, Simoni A, Mugnai L et al (1995) Increased production of nitric oxide by neutrophils and monocytes from cirrhotic patients with ascites and hyperdynamic circulation. Hepatology 22:1666\u20131673","journal-title":"Hepatology"},{"key":"437_CR25","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/BF00581523","volume":"391","author":"D Lebrec","year":"1981","unstructured":"Lebrec D, Blanchet L, Lacroix S (1981) Measurement of hepatic blood flow in the rat using fractional clearance of indocyanine green and colloidal radiogold. Pfl\u00fcgers Arch 391:353\u2013354","journal-title":"Pfl\u00fcgers Arch"},{"key":"437_CR26","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1136\/gut.2005.082446","volume":"55","author":"Y Li","year":"2006","unstructured":"Li Y, Liu H, Gaskari SA, McCafferty DM, Lee SS (2006) Hepatic venous dysregulation contributes to blood volume pooling in cirrhotic rats. Gut 55:1030\u20131035","journal-title":"Gut"},{"key":"437_CR27","doi-asserted-by":"crossref","first-page":"G567","DOI":"10.1152\/ajpgi.00452.2002","volume":"284","author":"MR Loureiro-Silva","year":"2003","unstructured":"Loureiro-Silva MR, Cadelina GW, Groszmann RJ (2003) Deficit in nitric oxide production in cirrhotic rat livers is located in the sinusoidal and postsinusoidal areas. Am J Physiol Gastrointest Liver Physiol 284:G567\u2013G574","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"437_CR28","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0168-8278(98)80152-9","volume":"29","author":"B Luo","year":"1998","unstructured":"Luo B, Abrams GA, Fallon MB (1998) Endothelin-1 in the rat bile duct ligation model of hepatopulmonary syndrome: correlation with pulmonary dysfunction. J Hepatol 29:571\u2013578","journal-title":"J Hepatol"},{"key":"437_CR29","first-page":"G416","volume":"267","author":"MK Mittal","year":"1994","unstructured":"Mittal MK, Gupta TK, Lee FY, Sieber CC, Groszmann RJ (1994) Nitric oxide modulates vascular tone in normal rat liver. Am J Physiol 267:G416\u2013G422","journal-title":"Am J Physiol"},{"key":"437_CR30","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1056\/NEJM199212173272502","volume":"327","author":"K Moore","year":"1992","unstructured":"Moore K, Wendon J, Frazer M, Krani J, Williams R et al (1992) Plasma endothelin immunoreactivity in liver disease and the hepatorenal syndrome. N Engl J Med 327:1774\u20131777","journal-title":"N Engl J Med"},{"key":"437_CR31","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1002\/hep.1840140650","volume":"14","author":"DJ Morgan","year":"1991","unstructured":"Morgan DJ, McLean AJ (1991) Therapeutic implications of impaired hepatic oxygen diffusion in chronic liver disease. Hepatology 14:1280\u20131282","journal-title":"Hepatology"},{"key":"437_CR32","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/0016-5085(81)90018-4","volume":"80","author":"H Orrego","year":"1981","unstructured":"Orrego H, Blendis LM, Crossley IR, Medline A, Macdonald A et al (1981) Correlation of intrahepatic pressure with collagen in the Disse space and hepatomegaly in humans and in the rat. Gastroenterology 80:546\u2013556","journal-title":"Gastroenterology"},{"key":"437_CR33","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1172\/JCI116334","volume":"91","author":"M Oshita","year":"1993","unstructured":"Oshita M, Takei Y, Kawanao S, Yoshihara H, Hijioka T et al (1993) Roles of endothelin-1 and nitric oxide in the mechanism of ethanol-induced vasoconstriction in rat liver. J Clin Invest 91:1337\u20131342","journal-title":"J Clin Invest"},{"key":"437_CR34","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1053\/gast.1996.v110.pm8566602","volume":"110","author":"M Pinzani","year":"1996","unstructured":"Pinzani M, Milani S, De Franco R, Grappone C, Caligiuri A et al (1996) Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells. Gastroenterology 110:534\u2013548","journal-title":"Gastroenterology"},{"key":"437_CR35","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1002\/hep.1840050312","volume":"5","author":"G Pomier-Layrargues","year":"1985","unstructured":"Pomier-Layrargues G, Kusielewicz D, Willems B, Villeneuve JP, Marleau D et al (1985) Presinusoidal portal hypertension in non-alchoholic cirrhosis. Hepatology 5:415\u2013418","journal-title":"Hepatology"},{"key":"437_CR36","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0016-5085(99)70240-4","volume":"116","author":"JL Poo","year":"1999","unstructured":"Poo JL, Jim\u00e9nez W, Mar\u00eda Mu\u00f1oz R, Bosch-Marc\u00e9 M, Bordas N et al (1999) Chronic blockade of endothelin receptors in cirrhotic rats: hepatic and hemodynamic effects. Gastroenterology 116:161\u2013167","journal-title":"Gastroenterology"},{"key":"437_CR37","first-page":"228","volume":"87","author":"H Popper","year":"1977","unstructured":"Popper H (1977) Pathologic aspects of cirrhosis. Am J Pathol 87:228\u2013258","journal-title":"Am J Pathol"},{"key":"437_CR38","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/S0168-8278(98)80352-8","volume":"28","author":"J Reichen","year":"1998","unstructured":"Reichen J, Gerbes AL, Steiner MJ, Sagesser H, Clozel M (1998) The effect of endothelin and its antagonist Bosentan on hemodynamics and microvascular exchange in cirrhotic rat liver. J Hepatol 28:1020\u20131030","journal-title":"J Hepatol"},{"key":"437_CR39","first-page":"G769","volume":"245","author":"GL Riedel","year":"1983","unstructured":"Riedel GL, Scholle JL, Shepherd AP, Ward WF (1983) Effects of hematocrit on oxygenation of the isolated perfused rat liver. Am J Physiol 245:G769\u2013G774","journal-title":"Am J Physiol"},{"key":"437_CR40","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/hep.510240137","volume":"24","author":"DC Rockey","year":"1996","unstructured":"Rockey DC, Weisiger RA (1996) Endothelin induced contractility of stellate cells from normal and cirrhotic rat liver: implications for regulation of portal pressure and resistance. Hepatology 24:233\u2013240","journal-title":"Hepatology"},{"key":"437_CR41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/hep.510250102","volume":"25","author":"DC Rockey","year":"1997","unstructured":"Rockey DC (1997) The cellular pathogenesis of portal hypertension: Stellate cells contractility, endothelin, and nitric oxide. Hepatology 25:1\u20135","journal-title":"Hepatology"},{"key":"437_CR42","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1002\/hep.510270222","volume":"27","author":"DC Rockey","year":"1998","unstructured":"Rockey DC, Fouassier L, Chung JJ, Carayon A, Vallee P et al (1998) Cellular localization of endothelin-1 and increased production in liver injury in the rat: potential for autocrine and paracrine effects on stellate cells. Hepatology 27:472\u2013480","journal-title":"Hepatology"},{"key":"437_CR43","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1055\/s-2001-17551","volume":"21","author":"DC Rockey","year":"2001","unstructured":"Rockey DC (2001) Hepatic blood flow regulation by stellate cells in normal and injured liver. Seminar Liver Dis 21:337\u2013349","journal-title":"Seminar Liver Dis"},{"key":"437_CR44","first-page":"554","volume":"21","author":"J Ros","year":"1995","unstructured":"Ros J, Jimenez W, Lamas S, Claria J, Arroyo V et al (1995) Nitric oxide production in arterial vessels of cirrhotic rats. Hepatology 21:554\u2013560","journal-title":"Hepatology"},{"key":"437_CR45","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1002\/hep.1840130329","volume":"13","author":"SK Sarin","year":"1991","unstructured":"Sarin SK, Mosca P, Sabba C, Groszmann RJ (1991) Hyperdynamic circulation in a chronic murine schistosomiasis model of portal hypertension. Hepatology 13:581\u2013584","journal-title":"Hepatology"},{"key":"437_CR46","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/hep.510270141","volume":"27","author":"V Shah","year":"1998","unstructured":"Shah V, Garcia-Cardena G, Sessa WC, Groszmann RJ (1998) The hepatic circulation in health and disease: report of a single-topic symposium. Hepatology 27:279\u2013288","journal-title":"Hepatology"},{"key":"437_CR47","doi-asserted-by":"crossref","first-page":"H1436","DOI":"10.1152\/ajpheart.00368.2005","volume":"289","author":"T Shibamoto","year":"2005","unstructured":"Shibamoto T, Cui S, Ruan Z, Liu W, Takano H et al (2005) Hepatic venoconstriction is involved in anaphylactic hypotension in rats. Am J Physiol Heart Circ Physiol 289:H1436\u2013H1441","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"437_CR48","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1600-0676.1988.tb00974.x","volume":"8","author":"Y Shibayama","year":"1988","unstructured":"Shibayama Y (1988) On the pathogenesis of portal hypertension in cirrhosis of the liver. Liver 8:95\u201399","journal-title":"Liver"},{"key":"437_CR49","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1002\/hep.1840050421","volume":"5","author":"Y Shibayama","year":"1985","unstructured":"Shibayama Y, Nakata K (1985) Localization of increased hepatic vascular resistance in liver cirrhosis. Hepatology 5:643\u2013648","journal-title":"Hepatology"},{"key":"437_CR50","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1161\/01.HYP.33.1.581","volume":"33","author":"FE Strachan","year":"1999","unstructured":"Strachan FE, Spratt JC, Wilkinson IB, Johnston NR, Gray GA et al (1999) Systemic blockade of the endothelin-B receptor increases peripheral vascular resistance in healthy men. Hypertension 33:581\u2013585","journal-title":"Hypertension"},{"key":"437_CR51","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1111\/j.1476-5381.1992.tb14537.x","volume":"107","author":"MJ Sumner","year":"1992","unstructured":"Sumner MJ, Cannon TR, Mundin JW, White DG, Watts IS (1992) Endothelin ETA and ETB receptors mediate vascular smooth muscle contraction. Br J Pharmacol 107:858\u2013860","journal-title":"Br J Pharmacol"},{"key":"437_CR52","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1055\/s-2008-1040457","volume":"10","author":"H Tsukamoto","year":"1990","unstructured":"Tsukamoto H, Matsuoka M, French SW (1990) Experimental models of hepatic fibrosis: a review. Semin Liver Dis 10:56\u201365","journal-title":"Semin Liver Dis"},{"key":"437_CR53","doi-asserted-by":"crossref","first-page":"G1036","DOI":"10.1152\/ajpgi.1997.273.5.G1036","volume":"273","author":"H-G Wang","year":"1997","unstructured":"Wang H-G, Shibamoto T, Miyahara T (1997) Endothelin-1 selectively contracts portal vein through both ETA and ETB receptors in isolated perfused rabbit liver. Am J Physiol Gastrointest Liver Physiol 273:G1036\u2013G1043","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"437_CR54","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1055\/s-2007-1007129","volume":"19","author":"R Wiest","year":"1999","unstructured":"Wiest R, Groszmann RJ (1999) Nitric oxide and portal hypertension: Its role in the regulation of intrahepatic and splanchnic vascular resistance. Seminar Liver Dis 19:411\u2013426","journal-title":"Seminar Liver Dis"},{"key":"437_CR55","first-page":"167","volume":"83","author":"PC Yu","year":"1992","unstructured":"Yu PC, Kuo JS, Lin HC, Yang MCM (1992) Effects of endothelin in portal hypertensive rats. Clin Sci 83:167\u2013170","journal-title":"Clin Sci"},{"key":"437_CR56","doi-asserted-by":"crossref","first-page":"G624","DOI":"10.1152\/ajpgi.1994.266.4.G624","volume":"266","author":"JX Zhang","year":"1994","unstructured":"Zhang JX, Pegoli W Jr, Clemens MG (1994) Endothelin-1 induces direct constriction of hepatic sinusoids. Am J Physiol Gastrointest Liver Physiol 266:G624\u2013G632","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"437_CR57","doi-asserted-by":"crossref","first-page":"G269","DOI":"10.1152\/ajpgi.1995.269.2.G269","volume":"269","author":"JX Zhang","year":"1995","unstructured":"Zhang JX, Bauer M, Clemens MG (1995) Vessel- and target cell-specific actions of endothelin-1 and endothelin-3 in rat liver. Am J Physiol Gastrointest Liver Physiol 269:G269\u2013G277","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"437_CR58","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1053\/jhep.2003.50065","volume":"37","author":"A Zipprich","year":"2003","unstructured":"Zipprich A, Steudel N, Behrmann C, Meiss F, Sziegoleit U et al (2003) Functional significance of hepatic arterial flow reserve in patients with cirrhosis. Hepatology 37:385\u2013392","journal-title":"Hepatology"}],"container-title":["Pfl\u00fcgers Archiv - European Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-007-0437-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00424-007-0437-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-007-0437-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T20:52:28Z","timestamp":1559076748000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00424-007-0437-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1,5]]},"references-count":58,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["437"],"URL":"https:\/\/doi.org\/10.1007\/s00424-007-0437-6","relation":{},"ISSN":["0031-6768","1432-2013"],"issn-type":[{"value":"0031-6768","type":"print"},{"value":"1432-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1,5]]}}}