{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T17:18:56Z","timestamp":1783444736056,"version":"3.54.6"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2012,12,4]],"date-time":"2012-12-04T00:00:00Z","timestamp":1354579200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pflugers Arch - Eur J Physiol"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1007\/s00424-012-1181-0","type":"journal-article","created":{"date-parts":[[2012,12,3]],"date-time":"2012-12-03T16:03:00Z","timestamp":1354550580000},"page":"481-495","source":"Crossref","is-referenced-by-count":52,"title":["Role of bestrophin-1 in store-operated calcium entry in retinal pigment epithelium"],"prefix":"10.1007","volume":"465","author":[{"given":"N\u00e9stor M\u00e1s","family":"G\u00f3mez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernst R.","family":"Tamm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaf","family":"Strau\u03b2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,12,4]]},"reference":[{"issue":"2","key":"1181_CR1","first-page":"36\u00df42","volume":"11","author":"MD Abramoff","year":"2004","unstructured":"Abramoff MD, Magelhaes PJ, Ram SJ, Zhang S, Campochiaro PA, Zack DJ, Hughes BA (2004) Image processing with image. J Biophotonics Int 11(2):36\u00df42","journal-title":"J Biophotonics Int"},{"issue":"8","key":"1181_CR2","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1136\/bjo.46.8.449","volume":"46","author":"GB Arden","year":"1962","unstructured":"Arden GB, Barrada A, Kelsey JH (1962) New clinical test of retinal function based upon the standing potential of the eye. Br J Ophthalmol 46(8):449\u2013467","journal-title":"Br J Ophthalmol"},{"issue":"8","key":"1181_CR3","doi-asserted-by":"crossref","first-page":"3622","DOI":"10.1167\/iovs.03-0030","volume":"44","author":"B Bakall","year":"2003","unstructured":"Bakall B, Marmorstein LY, Hoppe G, Peachey NS, Wadelius C, Marmorstein AD (2003) Expression and localization of bestrophin during normal mouse development. Invest Ophthalmol Vis Sci 44(8):3622\u20133628","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"43","key":"1181_CR4","doi-asserted-by":"crossref","first-page":"29405","DOI":"10.1074\/jbc.M605716200","volume":"284","author":"R Barro Soria","year":"2009","unstructured":"Barro Soria R, Spitzner M, Schreiber R, Kunzelmann K (2009) Bestrophin-1 enables Ca2+-activated Cl\u2212 conductance in epithelia. J Biol Chem 284(43):29405\u201329412. doi: 10.1074\/jbc.M605716200","journal-title":"J Biol Chem"},{"issue":"3","key":"1181_CR5","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00424-009-0745-0","volume":"459","author":"R Barro-Soria","year":"2010","unstructured":"Barro-Soria R, Aldehni F, Almaca J, Witzgall R, Schreiber R, Kunzelmann K (2010) ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel. Pflugers Arch 459(3):485\u2013497. doi: 10.1007\/s00424-009-0745-0","journal-title":"Pflugers Arch"},{"issue":"6410","key":"1181_CR6","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/361315a0","volume":"361","author":"MJ Berridge","year":"1993","unstructured":"Berridge MJ (1993) Inositol trisphosphate and calcium signalling. Nature 361(6410):315\u2013325. doi: 10.1038\/361315a0","journal-title":"Nature"},{"key":"1181_CR7","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1242\/jcs.1993.Supplement_17.27","volume":"17","author":"D Bok","year":"1993","unstructured":"Bok D (1993) The retinal pigment epithelium: a versatile partner in vision. J Cell Sci Suppl 17:189\u2013195","journal-title":"J Cell Sci Suppl"},{"issue":"7","key":"1181_CR8","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/j.cell.2007.11.039","volume":"131","author":"O Brandman","year":"2007","unstructured":"Brandman O, Liou J, Park WS, Meyer T (2007) STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels. Cell 131(7):1327\u20131339. doi: 10.1016\/j.cell.2007.11.039","journal-title":"Cell"},{"issue":"2","key":"1181_CR9","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.ceca.2007.03.002","volume":"42","author":"MD Cahalan","year":"2007","unstructured":"Cahalan MD, Zhang SL, Yeromin AV, Ohlsen K, Roos J, Stauderman KA (2007) Molecular basis of the CRAC channel. Cell Calcium 42(2):133\u2013144. doi: 10.1016\/j.ceca.2007.03.002","journal-title":"Cell Calcium"},{"issue":"5","key":"1181_CR10","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/s00417-010-1604-6","volume":"249","author":"PA Constable","year":"2011","unstructured":"Constable PA (2011) Nifedipine alters the light-rise of the electro-oculogram in man. Graefes Arch Clin Exp Ophthalmol 249(5):677\u2013684. doi: 10.1007\/s00417-010-1604-6","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"1","key":"1181_CR11","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s00417-010-1445-3","volume":"249","author":"S Cordeiro","year":"2010","unstructured":"Cordeiro S, Strauss O (2010) Expression of Orai genes and I(CRAC) activation in the human retinal pigment epithelium. Graefes Arch Clin Exp Ophthalmol 249(1):47\u201354. doi: 10.1007\/s00417-010-1445-3","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"1","key":"1181_CR12","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s00417-010-1445-3","volume":"249","author":"S Cordeiro","year":"2011","unstructured":"Cordeiro S, Strauss O (2011) Expression of Orai genes and I(CRAC) activation in the human retinal pigment epithelium. Graefes Arch Clin Exp Ophthalmol 249(1):47\u201354. doi: 10.1007\/s00417-010-1445-3","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"7090","key":"1181_CR13","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nature04702","volume":"441","author":"S Feske","year":"2006","unstructured":"Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, Tanasa B, Hogan PG, Lewis RS, Daly M, Rao A (2006) A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441(7090):179\u2013185. doi: 10.1038\/nature04702","journal-title":"Nature"},{"issue":"3","key":"1181_CR14","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/81555","volume":"26","author":"A Gal","year":"2000","unstructured":"Gal A, Li Y, Thompson DA, Weir J, Orth U, Jacobson SG, Apfelstedt-Sylla E, Vollrath D (2000) Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. Nat Genet 26(3):270\u2013271. doi: 10.1038\/81555","journal-title":"Nat Genet"},{"issue":"6","key":"1181_CR15","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1016\/S0021-9258(19)83641-4","volume":"260","author":"G Grynkiewicz","year":"1985","unstructured":"Grynkiewicz G, Poenie M, Tsien RY (1985) A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 260(6):3440\u20133450","journal-title":"J Biol Chem"},{"issue":"2","key":"1181_CR16","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/ng1097-194","volume":"17","author":"SM Gu","year":"1997","unstructured":"Gu SM, Thompson DA, Srikumari CR, Lorenz B, Finckh U, Nicoletti A, Murthy KR, Rathmann M, Kumaramanickavel G, Denton MJ, Gal A (1997) Mutations in RPE65 cause autosomal recessive childhood-onset severe retinal dystrophy. Nat Genet 17(2):194\u2013197. doi: 10.1038\/ng1097-194","journal-title":"Nat Genet"},{"issue":"2","key":"1181_CR17","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1152\/physrev.00022.2007","volume":"88","author":"HC Hartzell","year":"2008","unstructured":"Hartzell HC, Qu Z, Yu K, Xiao Q, Chien LT (2008) Molecular physiology of bestrophins: multifunctional membrane proteins linked to best disease and other retinopathies. Physiol Rev 88(2):639\u2013672. doi: 10.1152\/physrev.00022.2007","journal-title":"Physiol Rev"},{"key":"1181_CR18","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1146\/annurev.immunol.021908.132550","volume":"28","author":"PG Hogan","year":"2010","unstructured":"Hogan PG, Lewis RS, Rao A (2010) Molecular basis of calcium signaling in lymphocytes: STIM and ORAI. Annu Rev Immunol 28:491\u2013533. doi: 10.1146\/annurev.immunol.021908.132550","journal-title":"Annu Rev Immunol"},{"issue":"6358","key":"1181_CR19","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/355353a0","volume":"355","author":"M Hoth","year":"1992","unstructured":"Hoth M, Penner R (1992) Depletion of intracellular calcium stores activates a calcium current in mast cells. Nature 355(6358):353\u2013356. doi: 10.1038\/355353a0","journal-title":"Nature"},{"issue":"8","key":"1181_CR20","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1172\/JCI25470","volume":"115","author":"TJ Jentsch","year":"2005","unstructured":"Jentsch TJ, Maritzen T, Zdebik AA (2005) Chloride channel diseases resulting from impaired transepithelial transport or vesicular function. J Clin Invest 115(8):2039\u20132046. doi: 10.1172\/JCI25470","journal-title":"J Clin Invest"},{"issue":"13","key":"1181_CR21","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/j.cub.2005.05.055","volume":"15","author":"J Liou","year":"2005","unstructured":"Liou J, Kim ML, Heo WD, Jones JT, Myers JW, Ferrell JE Jr, Meyer T (2005) STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx. Curr Biol 15(13):1235\u20131241. doi: 10.1016\/j.cub.2005.05.055","journal-title":"Curr Biol"},{"issue":"23","key":"1181_CR22","doi-asserted-by":"crossref","first-page":"12758","DOI":"10.1073\/pnas.220402097","volume":"97","author":"AD Marmorstein","year":"2000","unstructured":"Marmorstein AD, Marmorstein LY, Rayborn M, Wang X, Hollyfield JG, Petrukhin K (2000) Bestrophin, the product of the Best vitelliform macular dystrophy gene (VMD2), localizes to the basolateral plasma membrane of the retinal pigment epithelium. Proc Natl Acad Sci U S A 97(23):12758\u201312763. doi: 10.1073\/pnas.220402097","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"1181_CR23","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1085\/jgp.200509473","volume":"127","author":"LY Marmorstein","year":"2006","unstructured":"Marmorstein LY, Wu J, McLaughlin P, Yocom J, Karl MO, Neussert R, Wimmers S, Stanton JB, Gregg RG, Strauss O, Peachey NS, Marmorstein AD (2006) The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1). J Gen Physiol 127(5):577\u2013589. doi: 10.1085\/jgp.200509473","journal-title":"J Gen Physiol"},{"issue":"9","key":"1181_CR24","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1093\/hmg\/7.9.1517","volume":"7","author":"A Marquardt","year":"1998","unstructured":"Marquardt A, Stohr H, Passmore LA, Kramer F, Rivera A, Weber BH (1998) Mutations in a novel gene, VMD2, encoding a protein of unknown properties cause juvenile-onset vitelliform macular dystrophy (Best\u2019s disease). Hum Mol Genet 7(9):1517\u20131525","journal-title":"Hum Mol Genet"},{"key":"1181_CR25","first-page":"1385","volume":"11","author":"JR Martins","year":"1812","unstructured":"Martins JR, Kongsuphol P, Sammels E, Dahimene S, Aldehni F, Clarke LA, Schreiber R, de Smedt H, Amaral MD (1812) Kunzelmann K F508del-CFTR increases intracellular Ca(2+) signaling that causes enhanced calcium-dependent Cl(\u2212) conductance in cystic fibrosis. Biochim Biophys Acta 11:1385\u20131392. doi: 10.1016\/j.bbadis.2011.08.008","journal-title":"Biochim Biophys Acta"},{"issue":"2","key":"1181_CR26","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1038\/ng1097-198","volume":"17","author":"MA Maw","year":"1997","unstructured":"Maw MA, Kennedy B, Knight A, Bridges R, Roth KE, Mani EJ, Mukkadan JK, Nancarrow D, Crabb JW, Denton MJ (1997) Mutation of the gene encoding cellular retinaldehyde-binding protein in autosomal recessive retinitis pigmentosa. Nat Genet 17(2):198\u2013200. doi: 10.1038\/ng1097-198","journal-title":"Nat Genet"},{"issue":"1","key":"1181_CR27","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/exer.2001.1128","volume":"74","author":"S Mergler","year":"2002","unstructured":"Mergler S, Strauss O (2002) Stimulation of L-type Ca(2+) channels by increase of intracellular InsP3 in rat retinal pigment epithelial cells. Exp Eye Res 74(1):29\u201340. doi: 10.1006\/exer.2001.1128S0014483501911285","journal-title":"Exp Eye Res"},{"issue":"4","key":"1181_CR28","doi-asserted-by":"crossref","first-page":"e19364","DOI":"10.1371\/journal.pone.0019364","volume":"6","author":"VM Milenkovic","year":"2011","unstructured":"Milenkovic VM, Krejcova S, Reichhart N, Wagner A, Strauss O (2011) Interaction of bestrophin-1 and Ca2+ channel beta-subunits: identification of new binding domains on the bestrophin-1 C-terminus. PLoS One 6(4):e19364. doi: 10.1371\/journal.pone.0019364PONE-D-10-05789","journal-title":"PLoS One"},{"issue":"Pt 17","key":"1181_CR29","doi-asserted-by":"crossref","first-page":"2988","DOI":"10.1242\/jcs.085878","volume":"124","author":"VM Milenkovic","year":"2011","unstructured":"Milenkovic VM, Rohrl E, Weber BH, Strauss O (2011) Disease-associated missense mutations in bestrophin-1 affect cellular trafficking and anion conductance. J Cell Sci 124(Pt 17):2988\u20132996. doi: 10.1242\/jcs.085878","journal-title":"J Cell Sci"},{"issue":"11","key":"1181_CR30","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1001\/archopht.123.11.1588","volume":"123","author":"RF Mullins","year":"2005","unstructured":"Mullins RF, Oh KT, Heffron E, Hageman GS, Stone EM (2005) Late development of vitelliform lesions and flecks in a patient with best disease: clinicopathologic correlation. Arch Ophthalmol 123(11):1588\u20131594. doi: 10.1001\/archopht.123.11.1588","journal-title":"Arch Ophthalmol"},{"issue":"1","key":"1181_CR31","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00424-010-0840-2","volume":"460","author":"R Neussert","year":"2010","unstructured":"Neussert R, Muller C, Milenkovic VM, Strauss O (2010) The presence of bestrophin-1 modulates the Ca2+ recruitment from Ca2+ stores in the ER. Pflugers Arch 460(1):163\u2013175. doi: 10.1007\/s00424-010-0840-2","journal-title":"Pflugers Arch"},{"issue":"5","key":"1181_CR32","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/nrd3136","volume":"9","author":"AB Parekh","year":"2010","unstructured":"Parekh AB (2010) Store-operated CRAC channels: function in health and disease. Nat Rev Drug Discov 9(5):399\u2013410. doi: 10.1038\/nrd3136","journal-title":"Nat Rev Drug Discov"},{"issue":"3","key":"1181_CR33","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/915","volume":"19","author":"K Petrukhin","year":"1998","unstructured":"Petrukhin K, Koisti MJ, Bakall B, Li W, Xie G, Marknell T, Sandgren O, Forsman K, Holmgren G, Andreasson S, Vujic M, Bergen AA, McGarty-Dugan V, Figueroa D, Austin CP, Metzker ML, Caskey CT, Wadelius C (1998) Identification of the gene responsible for Best macular dystrophy. Nat Genet 19(3):241\u2013247. doi: 10.1038\/915","journal-title":"Nat Genet"},{"issue":"5","key":"1181_CR34","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.exer.2010.08.001","volume":"91","author":"N Reichhart","year":"2010","unstructured":"Reichhart N, Milenkovic VM, Halsband CA, Cordeiro S, Strauss O (2010) Effect of bestrophin-1 on L-type Ca2+ channel activity depends on the Ca2+ channel beta-subunit. Exp Eye Res 91(5):630\u2013639. doi: 10.1016\/j.exer.2010.08.001","journal-title":"Exp Eye Res"},{"issue":"3","key":"1181_CR35","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1083\/jcb.200502019","volume":"169","author":"J Roos","year":"2005","unstructured":"Roos J, DiGregorio PJ, Yeromin AV, Ohlsen K, Lioudyno M, Zhang S, Safrina O, Kozak JA, Wagner SL, Cahalan MD, Velicelebi G, Stauderman KA (2005) STIM1, an essential and conserved component of store-operated Ca2+ channel function. J Cell Biol 169(3):435\u2013445. doi: 10.1083\/jcb.200502019","journal-title":"J Cell Biol"},{"issue":"1","key":"1181_CR36","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1096\/fj.05-4495fje","volume":"20","author":"R Rosenthal","year":"2006","unstructured":"Rosenthal R, Bakall B, Kinnick T, Peachey N, Wimmers S, Wadelius C, Marmorstein A, Strauss O (2006) Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca2+ channels in retinal pigment epithelial cells. FASEB J 20(1):178\u2013180. doi: 10.1096\/fj.05-4495fje","journal-title":"FASEB J"},{"issue":"29","key":"1181_CR37","doi-asserted-by":"crossref","first-page":"20261","DOI":"10.1074\/jbc.M803101200","volume":"283","author":"R Schindl","year":"2008","unstructured":"Schindl R, Bergsmann J, Frischauf I, Derler I, Fahrner M, Muik M, Fritsch R, Groschner K, Romanin C (2008) 2-Aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size. J Biol Chem 283(29):20261\u201320267. doi: 10.1074\/jbc.M803101200","journal-title":"J Biol Chem"},{"issue":"6","key":"1181_CR38","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1111\/j.1476-5381.2010.00786.x","volume":"160","author":"A Singh","year":"2010","unstructured":"Singh A, Hildebrand ME, Garcia E, Snutch TP (2010) The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channels. Br J Pharmacol 160(6):1464\u20131475. doi: 10.1111\/j.1476-5381.2010.00786.x","journal-title":"Br J Pharmacol"},{"issue":"2","key":"1181_CR39","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.bbamem.2006.01.024","volume":"1758","author":"JB Stanton","year":"2006","unstructured":"Stanton JB, Goldberg AF, Hoppe G, Marmorstein LY, Marmorstein AD (2006) Hydrodynamic properties of porcine bestrophin-1 in Triton X-100. Biochim Biophys Acta 1758(2):241\u2013247. doi: 10.1016\/j.bbamem.2006.01.024","journal-title":"Biochim Biophys Acta"},{"issue":"4","key":"1181_CR40","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/BF00158922","volume":"60","author":"RH Steinberg","year":"1985","unstructured":"Steinberg RH (1985) Interactions between the retinal pigment epithelium and the neural retina. Doc Ophthalmol 60(4):327\u2013346","journal-title":"Doc Ophthalmol"},{"issue":"3","key":"1181_CR41","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1152\/physrev.00021.2004","volume":"85","author":"O Strauss","year":"2005","unstructured":"Strauss O (2005) The retinal pigment epithelium in visual function. Physiol Rev 85(3):845\u2013881. doi: 10.1152\/physrev.00021.2004","journal-title":"Physiol Rev"},{"issue":"6","key":"1181_CR42","doi-asserted-by":"crossref","first-page":"4008","DOI":"10.1073\/pnas.052692999","volume":"99","author":"H Sun","year":"2002","unstructured":"Sun H, Tsunenari T, Yau KW, Nathans J (2002) The vitelliform macular dystrophy protein defines a new family of chloride channels. Proc Natl Acad Sci U S A 99(6):4008\u20134013. doi: 10.1073\/pnas.05269299999\/6\/4008","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"42","key":"1181_CR43","doi-asserted-by":"crossref","first-page":"41114","DOI":"10.1074\/jbc.M306150200","volume":"278","author":"T Tsunenari","year":"2003","unstructured":"Tsunenari T, Sun H, Williams J, Cahill H, Smallwood P, Yau KW, Nathans J (2003) Structure-function analysis of the bestrophin family of anion channels. J Biol Chem 278(42):41114\u201341125. doi: 10.1074\/jbc.M306150200M306150200","journal-title":"J Biol Chem"},{"issue":"7","key":"1181_CR44","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1001\/archopht.1982.01030040086016","volume":"100","author":"TA Weingeist","year":"1982","unstructured":"Weingeist TA, Kobrin JL, Watzke RC (1982) Histopathology of Best\u2019s macular dystrophy. Arch Ophthalmol 100(7):1108\u20131114","journal-title":"Arch Ophthalmol"},{"issue":"3","key":"1181_CR45","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.preteyeres.2006.12.002","volume":"26","author":"S Wimmers","year":"2007","unstructured":"Wimmers S, Karl MO, Strauss O (2007) Ion channels in the RPE. Prog Retin Eye Res 26(3):263\u2013301. doi: 10.1016\/j.preteyeres.2006.12.002","journal-title":"Prog Retin Eye Res"},{"issue":"5","key":"1181_CR46","doi-asserted-by":"crossref","first-page":"3731","DOI":"10.1152\/jn.00146.2007","volume":"97","author":"J Wu","year":"2007","unstructured":"Wu J, Marmorstein AD, Striessnig J, Peachey NS (2007) Voltage-dependent calcium channel CaV1.3 subunits regulate the light peak of the electroretinogram. J Neurophysiol 97(5):3731\u20133735. doi: 10.1152\/jn.00146.2007","journal-title":"J Neurophysiol"},{"issue":"7108","key":"1181_CR47","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/nature05108","volume":"443","author":"AV Yeromin","year":"2006","unstructured":"Yeromin AV, Zhang SL, Jiang W, Yu Y, Safrina O, Cahalan MD (2006) Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai. Nature 443(7108):226\u2013229. doi: 10.1038\/nature05108","journal-title":"Nature"},{"issue":"10","key":"1181_CR48","doi-asserted-by":"crossref","first-page":"4694","DOI":"10.1167\/iovs.07-0301","volume":"48","author":"K Yu","year":"2007","unstructured":"Yu K, Qu Z, Cui Y, Hartzell HC (2007) Chloride channel activity of bestrophin mutants associated with mild or late-onset macular degeneration. Invest Ophthalmol Vis Sci 48(10):4694\u20134705. doi: 10.1167\/iovs.07-0301","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"22","key":"1181_CR49","doi-asserted-by":"crossref","first-page":"5660","DOI":"10.1523\/JNEUROSCI.0065-08.2008","volume":"28","author":"K Yu","year":"2008","unstructured":"Yu K, Xiao Q, Cui G, Lee A, Hartzell HC (2008) The best disease-linked Cl\u2212 channel hBest1 regulates Ca V 1 (L-type) Ca2+ channels via src-homology-binding domains. J Neurosci 28(22):5660\u20135670. doi: 10.1523\/JNEUROSCI.0065-08.2008","journal-title":"J Neurosci"},{"key":"1181_CR50","doi-asserted-by":"crossref","unstructured":"Zhang Y, Stanton JB, Wu J, Yu K, Hartzell HC, Peachey NS, Marmorstein LY, Marmorstein AD Suppression of Ca2+ signaling in a mouse model of Best disease. Hum Mol Genet 19 (6):1108\u20131118. doi:10.1093\/hmg\/ddp583","DOI":"10.1093\/hmg\/ddp583"},{"issue":"6","key":"1181_CR51","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1093\/hmg\/ddp583","volume":"19","author":"Y Zhang","year":"2010","unstructured":"Zhang Y, Stanton JB, Wu J, Yu K, Hartzell HC, Peachey NS, Marmorstein LY, Marmorstein AD (2010) Suppression of Ca2+ signaling in a mouse model of Best disease. Hum Mol Genet 19(6):1108\u20131118. doi: 10.1093\/hmg\/ddp583","journal-title":"Hum Mol Genet"},{"issue":"24","key":"1181_CR52","doi-asserted-by":"crossref","first-page":"9357","DOI":"10.1073\/pnas.0603161103","volume":"103","author":"SL Zhang","year":"2006","unstructured":"Zhang SL, Yeromin AV, Zhang XH, Yu Y, Safrina O, Penna A, Roos J, Stauderman KA, Cahalan MD (2006) Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity. Proc Natl Acad Sci U S A 103(24):9357\u20139362. doi: 10.1073\/pnas.0603161103","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["Pfl\u00fcgers Archiv - European Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-012-1181-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00424-012-1181-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-012-1181-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T01:59:06Z","timestamp":1643767146000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00424-012-1181-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,4]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["1181"],"URL":"https:\/\/doi.org\/10.1007\/s00424-012-1181-0","relation":{},"ISSN":["0031-6768","1432-2013"],"issn-type":[{"value":"0031-6768","type":"print"},{"value":"1432-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,4]]}}}