{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T02:21:15Z","timestamp":1789611675099,"version":"build-2803163510"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2016,11,20]],"date-time":"2016-11-20T00:00:00Z","timestamp":1479600000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2016,11,20]],"date-time":"2016-11-20T00:00:00Z","timestamp":1479600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["15H01408"],"award-info":[{"award-number":["15H01408"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["26293021"],"award-info":[{"award-number":["26293021"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["16K15127"],"award-info":[{"award-number":["16K15127"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["16K08278"],"award-info":[{"award-number":["16K08278"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pflugers Arch - Eur J Physiol"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1007\/s00424-016-1900-z","type":"journal-article","created":{"date-parts":[[2016,11,19]],"date-time":"2016-11-19T23:35:27Z","timestamp":1479598527000},"page":"313-326","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Ryanodine receptor type 3 does not contribute to contractions in the mouse myometrium regardless of pregnancy"],"prefix":"10.1007","volume":"469","author":[{"given":"Katsuhito","family":"Matsuki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Takemoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiaki","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisao","family":"Yamamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susumu","family":"Ohya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Takeshima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Imaizumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,11,20]]},"reference":[{"key":"1900_CR1","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1038\/sj.bjp.0706644","volume":"147","author":"PI Aaronson","year":"2006","unstructured":"Aaronson PI, Sarwar U, Gin S, Rockenbauch U, Connolly M, Tillet A, Watson S, Liu B, Tribe RM (2006) A role for voltage-gated, but not Ca2+-activated, K+ channels in regulating spontaneous contractile activity in myometrium from virgin and pregnant rats. Br J Pharmacol 147:815\u2013824","journal-title":"Br J Pharmacol"},{"key":"1900_CR2","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1093\/humupd\/dmq016","volume":"16","author":"HN Aguilar","year":"2010","unstructured":"Aguilar HN, Mitchell BF (2010) Physiological pathways and molecular mechanisms regulating uterine contractility. Hum Reprod Update 16:725\u2013744","journal-title":"Hum Reprod Update"},{"key":"1900_CR3","doi-asserted-by":"crossref","first-page":"C976","DOI":"10.1152\/ajpcell.1993.265.4.C976","volume":"265","author":"K Anwer","year":"1993","unstructured":"Anwer K, Oberti C, Perez GJ, Perez-Reyes N, McDougall JK, Monga M, Sanborn BM, Stefani E, Toro L (1993) Calcium-activated K+ channels as modulators of human myometrial contractile activity. Am J Physiol Cell Physiol 265:C976\u2013C985","journal-title":"Am J Physiol Cell Physiol"},{"key":"1900_CR4","doi-asserted-by":"publisher","first-page":"5264","DOI":"10.1093\/emboj\/18.19.5264","volume":"18","author":"D Balschun","year":"1999","unstructured":"Balschun D, Wolfer DP, Bertocchini F, Barone V, Conti A, Zuschratter W, Missiaen L, Lipp HP, Frey JU, Sorrentino V (1999) Deletion of the ryanodine receptor type 3 (RyR3) impairs forms of synaptic plasticity and spatial learning. EMBO J 18:5264\u20135273","journal-title":"EMBO J"},{"key":"1900_CR5","doi-asserted-by":"crossref","first-page":"27712","DOI":"10.1074\/jbc.M000974200","volume":"275","author":"NA Benkusky","year":"2000","unstructured":"Benkusky NA, Fergus DJ, Zucchero TM, England SK (2000) Regulation of the Ca2+-sensitive domains of the maxi-K channel in the mouse myometrium during gestation. J Biol Chem 275:27712\u201327719","journal-title":"J Biol Chem"},{"key":"1900_CR6","doi-asserted-by":"publisher","first-page":"C779","DOI":"10.1152\/ajpcell.00173.2008","volume":"295","author":"R Berra-Romani","year":"2008","unstructured":"Berra-Romani R, Mazzocco-Spezzia A, Pulina MV, Golovina VA (2008) Ca2+ handling is altered when arterial myocytes progress from a contractile to a proliferative phenotype in culture. Am J Physiol Cell Physiol 295:C779\u2013C790","journal-title":"Am J Physiol Cell Physiol"},{"key":"1900_CR7","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1196\/annals.1389.002","volume":"1101","author":"T Burdyga","year":"2007","unstructured":"Burdyga T, Wray S, Noble K (2007) In situ calcium signaling: no calcium sparks detected in rat myometrium. Ann N Y Acad Sci 1101:85\u201396","journal-title":"Ann N Y Acad Sci"},{"key":"1900_CR8","doi-asserted-by":"publisher","first-page":"C848","DOI":"10.1152\/ajpcell.00069.2007","volume":"293","author":"F Dabertrand","year":"2007","unstructured":"Dabertrand F, Fritz N, Mironneau J, Macrez N, Morel JL (2007) Role of RYR3 splice variants in calcium signaling in mouse nonpregnant and pregnant myometrium. Am J Physiol Cell Physiol 293:C848\u2013C854","journal-title":"Am J Physiol Cell Physiol"},{"key":"1900_CR9","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.ceca.2007.11.009","volume":"44","author":"F Dabertrand","year":"2008","unstructured":"Dabertrand F, Mironneau J, Macrez N, Morel JL (2008) Full length ryanodine receptor subtype 3 encodes spontaneous calcium oscillations in native duodenal smooth muscle cells. Cell Calcium 44:180\u2013189","journal-title":"Cell Calcium"},{"key":"1900_CR10","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.ceca.2006.03.008","volume":"40","author":"F Dabertrand","year":"2006","unstructured":"Dabertrand F, Morel JL, Sorrentino V, Mironneau J, Mironneau C, Macrez N (2006) Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells. Cell Calcium 40:11\u201321","journal-title":"Cell Calcium"},{"key":"1900_CR11","doi-asserted-by":"publisher","first-page":"4310","DOI":"10.1210\/jc.2003-030221","volume":"88","author":"HC Doheny","year":"2003","unstructured":"Doheny HC, Houlihan DD, Ravikumar N, Smith TJ, Morrison JJ (2003) Human chorionic gonadotrophin relaxation of human pregnant myometrium and activation of the BKCa channel. J Clin Endocrinol Metab 88:4310\u20134315","journal-title":"J Clin Endocrinol Metab"},{"key":"1900_CR12","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1085\/jgp.85.2.291","volume":"85","author":"A Fabiato","year":"1985","unstructured":"Fabiato A (1985) Simulated calcium current can both cause calcium loading in and trigger calcium release from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell. J Gen Physiol 85:291\u2013320","journal-title":"J Gen Physiol"},{"key":"1900_CR13","first-page":"3966","volume":"118","author":"KM Fetalvero","year":"2008","unstructured":"Fetalvero KM, Zhang P, Shyu M, Young BT, Hwa J, Young RC, Martin KA (2008) Prostacyclin primes pregnant human myometrium for an enhanced contractile response in parturition. J Clin Invest 118:3966\u20133979","journal-title":"J Clin Invest"},{"key":"1900_CR14","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1016\/S0896-6273(00)81123-X","volume":"24","author":"A Futatsugi","year":"1999","unstructured":"Futatsugi A, Kato K, Ogura H, Li ST, Nagata E, Kuwajima G, Tanaka K, Itohara S, Mikoshiba K (1999) Facilitation of NMDAR-independent LTP and spatial learning in mutant mice lacking ryanodine receptor type 3. Neuron 24:701\u2013713","journal-title":"Neuron"},{"key":"1900_CR15","doi-asserted-by":"publisher","first-page":"2313","DOI":"10.1113\/jphysiol.2009.171272","volume":"587","author":"IA Greenwood","year":"2009","unstructured":"Greenwood IA, Yeung SY, Tribe RM, Ohya S (2009) Loss of functional K+ channels encoded by ether-a-go-go-related genes in mouse myometrium prior to labour onset. J Physiol 587:2313\u20132326","journal-title":"J Physiol"},{"key":"1900_CR16","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/0014-5793(92)80941-9","volume":"312","author":"Y Hakamata","year":"1992","unstructured":"Hakamata Y, Nakai J, Takeshima H, Imoto K (1992) Primary structure and distribution of a novel ryanodine receptor\/calcium release channel from rabbit brain. FEBS Lett 312:229\u2013235","journal-title":"FEBS Lett"},{"key":"1900_CR17","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1113\/jphysiol.2007.130302","volume":"582","author":"S Hotta","year":"2007","unstructured":"Hotta S, Morimura K, Ohya S, Muraki K, Takeshima H, Imaizumi Y (2007) Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladder smooth muscle. J Physiol 582:489\u2013506","journal-title":"J Physiol"},{"key":"1900_CR18","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1085\/jgp.94.2.363","volume":"94","author":"M Iino","year":"1989","unstructured":"Iino M (1989) Calcium-induced calcium release mechanism in guinea pig taenia caeci. J Gen Physiol 94:363\u2013383","journal-title":"J Gen Physiol"},{"key":"1900_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1254\/jjp.80.1","volume":"80","author":"Y Imaizumi","year":"1999","unstructured":"Imaizumi Y, Ohi Y, Yamamura H, Ohya S, Muraki K, Watanabe M (1999) Ca2+ spark as a regulator of ion channel activity. Jpn J Pharmacol 80:1\u20138","journal-title":"Jpn J Pharmacol"},{"key":"1900_CR20","doi-asserted-by":"crossref","first-page":"C235","DOI":"10.1152\/ajpcell.2000.278.2.C235","volume":"278","author":"JH Jaggar","year":"2000","unstructured":"Jaggar JH, Porter VA, Lederer WJ, Nelson MT (2000) Calcium sparks in smooth muscle. Am J Physiol Cell Physiol 278:C235\u2013C256","journal-title":"Am J Physiol Cell Physiol"},{"key":"1900_CR21","doi-asserted-by":"publisher","first-page":"4763","DOI":"10.1074\/jbc.M210410200","volume":"278","author":"D Jiang","year":"2003","unstructured":"Jiang D, Xiao B, Li X, Chen SR (2003) Smooth muscle tissues express a major dominant negative splice variant of the type 3 Ca2+ release channel (ryanodine receptor). J Biol Chem 278:4763\u20134769","journal-title":"J Biol Chem"},{"key":"1900_CR22","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1093\/humrep\/13.1.208","volume":"13","author":"RN Khan","year":"1998","unstructured":"Khan RN, Smith SK, Ashford ML (1998) Contribution of calcium-sensitive potassium channels to NS1619-induced relaxation in human pregnant myometrium. Hum Reprod 13:208\u2013213","journal-title":"Hum Reprod"},{"key":"1900_CR23","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1210\/endo.137.2.8593830","volume":"137","author":"T Kimura","year":"1996","unstructured":"Kimura T, Takemura M, Nomura S, Nobunaga T, Kubota Y, Inoue T, Hashimoto K, Kumazawa I, Ito Y, Ohashi K, Koyama M, Azuma C, Kitamura Y, Saji F (1996) Expression of oxytocin receptor in human pregnant myometrium. Endocrinology 137:780\u2013785","journal-title":"Endocrinology"},{"key":"1900_CR24","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/S0169-328X(99)00344-7","volume":"76","author":"Y Kouzu","year":"2000","unstructured":"Kouzu Y, Moriya T, Takeshima H, Yoshioka T, Shibata S (2000) Mutant mice lacking ryanodine receptor type 3 exhibit deficits of contextual fear conditioning and activation of calcium\/calmodulin-dependent protein kinase II in the hippocampus. Brain Res Mol Brain Res 76:142\u2013150","journal-title":"Brain Res Mol Brain Res"},{"key":"1900_CR25","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.1242\/jcs.01063","volume":"117","author":"S Kunerth","year":"2004","unstructured":"Kunerth S, Langhorst MF, Schwarzmann N, Gu X, Huang L, Yang Z, Zhang L, Mills SJ, Zhang LH, Potter BV, Guse AH (2004) Amplification and propagation of pacemaker Ca2+ signals by cyclic ADP-ribose and the type 3 ryanodine receptor in T cells. J Cell Sci 117:2141\u20132149","journal-title":"J Cell Sci"},{"key":"1900_CR26","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1124\/pr.56.4.1","volume":"56","author":"R Laporte","year":"2004","unstructured":"Laporte R, Hui A, Laher I (2004) Pharmacological modulation of sarcoplasmic reticulum function in smooth muscle. Pharmacol Rev 56:439\u2013513","journal-title":"Pharmacol Rev"},{"key":"1900_CR27","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1152\/physiol.00040.2005","volume":"21","author":"J Ledoux","year":"2006","unstructured":"Ledoux J, Werner ME, Brayden JE, Nelson MT (2006) Calcium-activated potassium channels and the regulation of vascular tone. Physiology (Bethesda) 21:69\u201378","journal-title":"Physiology (Bethesda)"},{"key":"1900_CR28","doi-asserted-by":"crossref","first-page":"C243","DOI":"10.1152\/ajpcell.1999.277.2.C243","volume":"277","author":"C Martin","year":"1999","unstructured":"Martin C, Hyvelin JM, Chapman KE, Marthan R, Ashley RH, Savineau JP (1999) Pregnant rat myometrial cells show heterogeneous ryanodine- and caffeine-sensitive calcium stores. Am J Physiol Cell Physiol 277:C243\u2013C252","journal-title":"Am J Physiol Cell Physiol"},{"key":"1900_CR29","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.jsgi.2003.10.009","volume":"11","author":"A Matthew","year":"2004","unstructured":"Matthew A, Kupittayanant S, Burdyga T, Wray S (2004) Characterization of contractile activity and intracellular Ca2+ signalling in mouse myometrium. J Soc Gynecol Investig 11:207\u2013212","journal-title":"J Soc Gynecol Investig"},{"key":"1900_CR30","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1113\/jphysiol.2001.013046","volume":"538","author":"J Mironneau","year":"2002","unstructured":"Mironneau J, Macrez N, Morel JL, Sorrentino V, Mironneau C (2002) Identification and function of ryanodine receptor subtype 3 in non-pregnant mouse myometrial cells. J Physiol 538:707\u2013716","journal-title":"J Physiol"},{"key":"1900_CR31","doi-asserted-by":"publisher","first-page":"C388","DOI":"10.1152\/ajpcell.00409.2005","volume":"290","author":"K Morimura","year":"2006","unstructured":"Morimura K, Ohi Y, Yamamura H, Ohya S, Muraki K, Imaizumi Y (2006) Two-step Ca2+ intracellular release underlies excitation-contraction coupling in mouse urinary bladder myocytes. Am J Physiol Cell Physiol 290:C388\u2013C403","journal-title":"Am J Physiol Cell Physiol"},{"key":"1900_CR32","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/0014-5793(90)80399-4","volume":"271","author":"J Nakai","year":"1990","unstructured":"Nakai J, Imagawa T, Hakamat Y, Shigekawa M, Takeshima H, Numa S (1990) Primary structure and functional expression from cDNA of the cardiac ryanodine receptor\/calcium release channel. FEBS Lett 271:169\u2013177","journal-title":"FEBS Lett"},{"key":"1900_CR33","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1126\/science.270.5236.633","volume":"270","author":"MT Nelson","year":"1995","unstructured":"Nelson MT, Cheng H, Rubart M, Santana LF, Bonev AD, Knot HJ, Lederer WJ (1995) Relaxation of arterial smooth muscle by calcium sparks. Science 270:633\u2013637","journal-title":"Science"},{"key":"1900_CR34","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.ceca.2009.11.004","volume":"47","author":"K Noble","year":"2010","unstructured":"Noble K, Floyd R, Shmygol A, Mobasheri A, Wray S (2010) Distribution, expression and functional effects of small conductance Ca-activated potassium (SK) channels in rat myometrium. Cell Calcium 47:47\u201354","journal-title":"Cell Calcium"},{"issue":"Suppl 1","key":"1900_CR35","doi-asserted-by":"publisher","first-page":"S11","DOI":"10.1016\/j.ejogrb.2009.02.010","volume":"144","author":"K Noble","year":"2009","unstructured":"Noble K, Matthew A, Burdyga T, Wray S (2009) A review of recent insights into the role of the sarcoplasmic reticulum and Ca entry in uterine smooth muscle. Eur J Obstet Gynecol Reprod Biol 144(Suppl 1):S11\u2013S19","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"1900_CR36","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1111\/j.1469-7793.2001.t01-3-00313.x","volume":"534","author":"Y Ohi","year":"2001","unstructured":"Ohi Y, Yamamura H, Nagano N, Ohya S, Muraki K, Watanabe M, Imaizumi Y (2001) Local Ca2+ transients and distribution of BK channels and ryanodine receptors in smooth muscle cells of guinea-pig vas deferens and urinary bladder. J Physiol 534:313\u2013326","journal-title":"J Physiol"},{"key":"1900_CR37","doi-asserted-by":"publisher","first-page":"16940","DOI":"10.1074\/jbc.M110.184192","volume":"286","author":"S Ohya","year":"2011","unstructured":"Ohya S, Niwa S, Yanagi A, Fukuyo Y, Yamamura H, Imaizumi Y (2011) Involvement of dominant-negative spliced variants of the intermediate conductance Ca2+-activated K+ channel, KCa3.1, in immune function of lymphoid cells. J Biol Chem 286:16940\u201316952","journal-title":"J Biol Chem"},{"key":"1900_CR38","doi-asserted-by":"crossref","first-page":"13472","DOI":"10.1016\/S0021-9258(18)77371-7","volume":"265","author":"K Otsu","year":"1990","unstructured":"Otsu K, Willard HF, Khanna VK, Zorzato F, Green NM, MacLennan DH (1990) Molecular cloning of cDNA encoding the Ca2+ release channel (ryanodine receptor) of rabbit cardiac muscle sarcoplasmic reticulum. J Biol Chem 265:13472\u201313483","journal-title":"J Biol Chem"},{"key":"1900_CR39","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1038\/sj.bjp.0705552","volume":"140","author":"H Ozaki","year":"2003","unstructured":"Ozaki H, Yasuda K, Kim YS, Egawa M, Kanzaki H, Nakazawa H, Hori M, Seto M, Karaki H (2003) Possible role of the protein kinase C\/CPI-17 pathway in the augmented contraction of human myometrium after gestation. Br J Pharmacol 140:1303\u20131312","journal-title":"Br J Pharmacol"},{"key":"1900_CR40","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1111\/j.1476-5381.1990.tb14691.x","volume":"99","author":"JP Savineau","year":"1990","unstructured":"Savineau JP, Mironneau J (1990) Caffeine acting on pregnant rat myometrium: analysis of its relaxant action and its failure to release Ca2+ from intracellular stores. Br J Pharmacol 99:261\u2013266","journal-title":"Br J Pharmacol"},{"key":"1900_CR41","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1111\/j.1469-7793.1998.803bg.x","volume":"511","author":"AV Shmigol","year":"1998","unstructured":"Shmigol AV, Eisner DA, Wray S (1998) Properties of voltage-activated [Ca2+]i transients in single smooth muscle cells isolated from pregnant rat uterus. J Physiol 511:803\u2013811","journal-title":"J Physiol"},{"key":"1900_CR42","doi-asserted-by":"crossref","unstructured":"Suzuki Y, Yamamura H, Ohya S, Imaizumi Y (2013) Caveolin-1 facilitates the direct coupling between large conductance Ca2+-activated K+ (BKCa) and Cav1.2 Ca2+ channels and their clustering to regulate membrane excitability in vascular myocytes. J Biol Chem 288:36750\u201336761","DOI":"10.1074\/jbc.M113.511485"},{"key":"1900_CR43","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1111\/j.1469-7793.1998.133bi.x","volume":"511","author":"MJ Taggart","year":"1998","unstructured":"Taggart MJ, Wray S (1998) Contribution of sarcoplasmic reticular calcium to smooth muscle contractile activation: gestational dependence in isolated rat uterus. J Physiol 511:133\u2013144","journal-title":"J Physiol"},{"key":"1900_CR44","doi-asserted-by":"publisher","first-page":"19649","DOI":"10.1074\/jbc.271.33.19649","volume":"271","author":"H Takeshima","year":"1996","unstructured":"Takeshima H, Ikemoto T, Nishi M, Nishiyama N, Shimuta M, Sugitani Y, Kuno J, Saito I, Saito H, Endo M, Iino M, Noda T (1996) Generation and characterization of mutant mice lacking ryanodine receptor type 3. J Biol Chem 271:19649\u201319652","journal-title":"J Biol Chem"},{"key":"1900_CR45","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1038\/339439a0","volume":"339","author":"H Takeshima","year":"1989","unstructured":"Takeshima H, Nishimura S, Matsumoto T, Ishida H, Kangawa K, Minamino N, Matsuo H, Ueda M, Hanaoka M, Hirose T et al (1989) Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor. Nature 339:439\u2013445","journal-title":"Nature"},{"key":"1900_CR46","doi-asserted-by":"publisher","first-page":"C999","DOI":"10.1152\/ajpcell.00158.2002","volume":"284","author":"GD Thorne","year":"2003","unstructured":"Thorne GD, Paul RJ (2003) Effects of organ culture on arterial gene expression and hypoxic relaxation: role of the ryanodine receptor. Am J Physiol Cell Physiol 284:C999\u2013C1005","journal-title":"Am J Physiol Cell Physiol"},{"key":"1900_CR47","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1172\/JCI116564","volume":"92","author":"RA Word","year":"1993","unstructured":"Word RA, Stull JT, Casey ML, Kamm KE (1993) Contractile elements and myosin light chain phosphorylation in myometrial tissue from nonpregnant and pregnant women. J Clin Invest 92:29\u201337","journal-title":"J Clin Invest"},{"key":"1900_CR48","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1152\/physrev.00018.2008","volume":"90","author":"S Wray","year":"2010","unstructured":"Wray S, Burdyga T (2010) Sarcoplasmic reticulum function in smooth muscle. Physiol Rev 90:113\u2013178","journal-title":"Physiol Rev"}],"container-title":["Pfl\u00fcgers Archiv - European Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-016-1900-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00424-016-1900-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-016-1900-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T06:15:00Z","timestamp":1657779300000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00424-016-1900-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,20]]},"references-count":48,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["1900"],"URL":"https:\/\/doi.org\/10.1007\/s00424-016-1900-z","relation":{},"ISSN":["0031-6768","1432-2013"],"issn-type":[{"value":"0031-6768","type":"print"},{"value":"1432-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,20]]},"assertion":[{"value":"29 August 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 October 2016","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 November 2016","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2016","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}