{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:33:12Z","timestamp":1790836392690,"version":"4.1.0"},"reference-count":73,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2018,5,2]],"date-time":"2018-05-02T00:00:00Z","timestamp":1525219200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100007136","name":"Secretar\u00eda de Estado de Investigaci\u00f3n, Desarrollo e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["SAF2013-44108-P"],"award-info":[{"award-number":["SAF2013-44108-P"]}],"id":[{"id":"10.13039\/501100007136","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007136","name":"Secretar\u00eda de Estado de Investigaci\u00f3n, Desarrollo e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["SAF2016-78892-R"],"award-info":[{"award-number":["SAF2016-78892-R"]}],"id":[{"id":"10.13039\/501100007136","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pflugers Arch - Eur J Physiol"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1007\/s00424-018-2147-7","type":"journal-article","created":{"date-parts":[[2018,5,2]],"date-time":"2018-05-02T10:08:55Z","timestamp":1525255735000},"page":"1255-1270","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Hydrogen sulphide facilitates exocytosis by regulating the handling of intracellular calcium by chromaffin cells"],"prefix":"10.1007","volume":"470","author":[{"given":"Ricardo","family":"de Pascual","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s M.","family":"Baraibar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iago","family":"M\u00e9ndez-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mart\u00edn","family":"P\u00e9rez-Ciria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Polo-Vaquero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9597-8519","authenticated-orcid":false,"given":"Luis","family":"Gand\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunny E.","family":"Ohia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio G.","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio M. G.","family":"de Diego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,5,2]]},"reference":[{"key":"2147_CR1","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1523\/JNEUROSCI.16-03-01066.1996","volume":"16","author":"K Abe","year":"1996","unstructured":"Abe K, Kimura H (1996) The possible role of hydrogen sulfide as an endogenous neuromodulator. J Neurosci 16:1066\u20131071","journal-title":"J Neurosci"},{"key":"2147_CR2","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1083\/jcb.144.2.241","volume":"144","author":"MT Alonso","year":"1999","unstructured":"Alonso MT, Barrero MJ, Michelena P, Carnicero E, Cuchillo I, Garcia AG, Garcia-Sancho J, Montero M, Alvarez J (1999) Ca2+-induced Ca2+ release in chromaffin cells seen from inside the ER with targeted aequorin. J Cell Biol 144:241\u2013254","journal-title":"J Cell Biol"},{"key":"2147_CR3","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1016\/j.bbrc.2007.10.151","volume":"365","author":"JJ Arnaiz-Cot","year":"2008","unstructured":"Arnaiz-Cot JJ, de Diego AM, Hern\u00e1ndez-Guijo JM, Gand\u00eda L, Garc\u00eda AG (2008) A two-step model for acetylcholine control of exocytosis via nicotinic receptors. Biochem Biophys Res Commun 365:413\u2013419","journal-title":"Biochem Biophys Res Commun"},{"key":"2147_CR4","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1113\/jphysiol.1992.sp019126","volume":"450","author":"GJ Augustine","year":"1992","unstructured":"Augustine GJ, Neher E (1992) Calcium requirements for secretion in bovine chromaffin cells. J Physiol 450:247\u2013271","journal-title":"J Physiol"},{"key":"2147_CR5","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1159\/000358690","volume":"33","author":"D Avanzato","year":"2014","unstructured":"Avanzato D, Merlino A, Porrera S, Wang R, Munaron L, Mancardi D (2014) Role of calcium channels in the protective effect of hydrogen sulfide in rat cardiomyoblasts. Cell Physiol Biochem 33:1205\u20131214","journal-title":"Cell Physiol Biochem"},{"key":"2147_CR6","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1124\/jpet.105.092023","volume":"316","author":"JS Bian","year":"2006","unstructured":"Bian JS, Yong QC, Pan TT, Feng ZN, Ali MY, Zhou S, Moore PK (2006) Role of hydrogen sulfide in the cardioprotection caused by ischemic preconditioning in the rat heart and cardiac myocytes. J Pharmacol Exp Ther 316:670\u2013678","journal-title":"J Pharmacol Exp Ther"},{"key":"2147_CR7","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/0165-0270(86)90054-3","volume":"16","author":"R Borges","year":"1986","unstructured":"Borges R, Sala F, Garcia AG (1986) Continuous monitoring of catecholamine release from perfused cat adrenals. J Neurosci Methods 16:289\u2013300","journal-title":"J Neurosci Methods"},{"key":"2147_CR8","doi-asserted-by":"publisher","first-page":"3205","DOI":"10.1378\/chest.128.5.3205","volume":"128","author":"YH Chen","year":"2005","unstructured":"Chen YH, Yao WZ, Geng B, Ding YL, Lu M, Zhao MW, Tang CS (2005) Endogenous hydrogen sulfide in patients with COPD. Chest 128:3205\u20133211","journal-title":"Chest"},{"key":"2147_CR9","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1113\/jphysiol.2004.064063","volume":"560","author":"I Cuchillo-Ib\u00e1\u00f1ez","year":"2004","unstructured":"Cuchillo-Ib\u00e1\u00f1ez I, Lejen T, Albillos A, Rose SD, Olivares R, Villarroya M, Garc\u00eda AG, Trifar\u00f3 JM (2004) Mitochondrial calcium sequestration and protein kinase C cooperate in the regulation of cortical F-actin disassembly and secretion in bovine chromaffin cells. J Physiol 560:63\u201376","journal-title":"J Physiol"},{"key":"2147_CR10","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/s00424-002-0810-4","volume":"444","author":"I Cuchillo-Ib\u00e1\u00f1ez","year":"2002","unstructured":"Cuchillo-Ib\u00e1\u00f1ez I, Olivares R, Aldea M, Villarroya M, Arroyo G, Fuentealba J, Garc\u00eda AG, Albillos A (2002) Acetylcholine and potassium elicit different patterns of exocytosis in chromaffin cells when the intracellular calcium handling is disturbed. Pflugers Arch 444:133\u2013142","journal-title":"Pflugers Arch"},{"key":"2147_CR11","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1111\/j.1748-1716.2007.01807.x","volume":"192","author":"AM Diego de","year":"2008","unstructured":"de Diego AM, Gandia L, Garcia AGA (2008) Physiological view of the central and peripheral mechanisms that regulate the release of catecholamines at the adrenal medulla. Acta Physiol (Oxf) 192:287\u2013301","journal-title":"Acta Physiol (Oxf)"},{"key":"2147_CR12","doi-asserted-by":"crossref","unstructured":"de Diego AM, Tapia L, Alvarez RM, Mosquera M, Cortes L, Lopez I, Gutierrez LM, Gandia L, Garcia AG (2008) A low nicotine concentration augments vesicle motion and exocytosis triggered by K+ depolarisation of chromaffin cells. Eur J Pharmacol 598:81\u201386","DOI":"10.1016\/j.ejphar.2008.09.003"},{"key":"2147_CR13","doi-asserted-by":"crossref","unstructured":"De Pascual R, Colmena I, Ruiz-Pascual L, Baraibar AM, Egea J, Gandia L, Garcia AG (2016) Regulation by L channels of Ca2+-evoked secretory responses in ouabain-treated chromaffin cells. Pflugers Arch 468:1779\u20131792","DOI":"10.1007\/s00424-016-1866-x"},{"key":"2147_CR14","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1113\/jphysiol.1963.sp007150","volume":"167","author":"WW Douglas","year":"1963","unstructured":"Douglas WW, Rubin RP (1963) The mechanism of catecholamine release from the adrenal medulla and the role of calcium in stimulus-secretion coupling. J Physiol 167:288\u2013310","journal-title":"J Physiol"},{"key":"2147_CR15","doi-asserted-by":"publisher","first-page":"4119","DOI":"10.1113\/JP270963","volume":"594","author":"J Elies","year":"2016","unstructured":"Elies J, Scragg JL, Boyle JP, Gamper N, Peers C (2016) Regulation of the T-type Ca2+ channel Cav3.2 by hydrogen sulfide: emerging controversies concerning the role of H2S in nociception. J Physiol 594:4119\u20134129","journal-title":"J Physiol"},{"key":"2147_CR16","doi-asserted-by":"publisher","first-page":"5376","DOI":"10.1096\/fj.14-257113","volume":"28","author":"J Elies","year":"2014","unstructured":"Elies J, Scragg JL, Huang S, Dallas ML, Huang D, MacDougall D, Boyle JP, Gamper N, Peers C (2014) Hydrogen sulfide inhibits Cav3.2 T-type Ca2+ channels. FASEB J 28:5376\u20135387","journal-title":"FASEB J"},{"key":"2147_CR17","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1016\/S0006-291X(02)00422-9","volume":"293","author":"K Eto","year":"2002","unstructured":"Eto K, Asada T, Arima K, Makifuchi T, Kimura H (2002) Brain hydrogen sulfide is severely decreased in Alzheimer\u2019s disease. Biochem Biophys Res Commun 293:1485\u20131488","journal-title":"Biochem Biophys Res Commun"},{"key":"2147_CR18","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1113\/jphysiol.1982.sp014394","volume":"331","author":"EM Fenwick","year":"1982","unstructured":"Fenwick EM, Marty A, Neher E (1982) Sodium and calcium channels in bovine chromaffin cells. J Physiol 331:599\u2013635","journal-title":"J Physiol"},{"key":"2147_CR19","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1152\/physrev.00039.2005","volume":"86","author":"AG Garcia","year":"2006","unstructured":"Garcia AG, Garcia-De-Diego AM, Gandia L, Borges R, Garcia-Sancho J (2006) Calcium signaling and exocytosis in adrenal chromaffin cells. Physiol Rev 86:1093\u20131131","journal-title":"Physiol Rev"},{"key":"2147_CR20","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.ceca.2011.12.004","volume":"51","author":"AG Garc\u00eda","year":"2012","unstructured":"Garc\u00eda AG, Pad\u00edn F, Fern\u00e1ndez-Morales JC, Maroto M, Garc\u00eda-Sancho J (2012) Cytosolic organelles shape calcium signals and exo-endocytotic responses of chromaffin cells. Cell Calcium 51:309\u2013320","journal-title":"Cell Calcium"},{"key":"2147_CR21","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1038\/309069a0","volume":"309","author":"AG Garcia","year":"1984","unstructured":"Garcia AG, Sala F, Reig JA, Viniegra S, Frias J, Fonteriz R, Gandia L (1984) Dihydropyridine BAY-K-8644 activates chromaffin cell calcium channels. Nature 309:69\u201371","journal-title":"Nature"},{"key":"2147_CR22","doi-asserted-by":"crossref","unstructured":"Garcia-Bereguiain MA, Samhan-Arias AK, Martin-Romero FJ, Gutierrez-Merino C (2008) Hydrogen sulfide raises cytosolic calcium in neurons through activation of L-type Ca2+ channels. Antioxid Redox Signal 10:31\u201342","DOI":"10.1089\/ars.2007.1656"},{"key":"2147_CR23","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s00424-012-1074-2","volume":"464","author":"J Garc\u00eda-Sancho","year":"2012","unstructured":"Garc\u00eda-Sancho J, de Diego AM, Garc\u00eda AG (2012) Mitochondria and chromaffin cell function. Pflugers Arch 464:33\u201341","journal-title":"Pflugers Arch"},{"key":"2147_CR24","doi-asserted-by":"crossref","unstructured":"Giovannucci DR, Hlubek MD, Stuenkel EL (1999) Mitochondria regulate the Ca2+-exocytosis relationship of bovine adrenal chromaffin cells. J Neurosci 19:9261\u20139270","DOI":"10.1523\/JNEUROSCI.19-21-09261.1999"},{"key":"2147_CR25","doi-asserted-by":"crossref","unstructured":"Goeger DE, Riley RT, Dorner JW, Cole RJ (1988) Cyclopiazonic acid inhibition of the Ca2+-transport ATPase in rat skeletal muscle sarcoplasmic reticulum vesicles. Biochem Pharmacol 37:978\u2013981","DOI":"10.1016\/0006-2952(88)90195-5"},{"key":"2147_CR26","doi-asserted-by":"crossref","unstructured":"Grynkiewicz G, Poenie M, Tsien RYA (1985) New generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440\u20133450","DOI":"10.1016\/S0021-9258(19)83641-4"},{"key":"2147_CR27","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1007\/BF00656997","volume":"391","author":"OP Hamill","year":"1981","unstructured":"Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391:85\u2013100","journal-title":"Pflugers Arch"},{"key":"2147_CR28","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1111\/j.1476-5381.2009.00385.x","volume":"158","author":"B Hennig","year":"2009","unstructured":"Hennig B, Diener M (2009) Actions of hydrogen sulphide on ion transport across rat distal colon. Br J Pharmacol 158:1263\u20131275","journal-title":"Br J Pharmacol"},{"key":"2147_CR29","doi-asserted-by":"publisher","first-page":"3352","DOI":"10.1111\/j.1742-4658.2008.06482.x","volume":"275","author":"TM Hildebrandt","year":"2008","unstructured":"Hildebrandt TM, Grieshaber MK (2008) Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria. FEBS J 275:3352\u20133361","journal-title":"FEBS J"},{"key":"2147_CR30","doi-asserted-by":"crossref","unstructured":"Inesi G, Sagara Y (1994) Specific inhibitors of intracellular Ca2+ transport ATPases. J Membr Biol 141:1\u20136","DOI":"10.1007\/BF00232868"},{"key":"2147_CR31","doi-asserted-by":"crossref","unstructured":"Jackson-Weaver O, Osmond JM, Riddle MA, Naik JS, Gonzalez Bosc LV, Walker BR, Kanagy NL (2013) Hydrogen sulfide dilates rat mesenteric arteries by activating endothelial large-conductance Ca2+-activated K+\u00a0channels and smooth muscle Ca2+ sparks. Am J Physiol Heart Circ Physiol 304:H1446\u2013H1454","DOI":"10.1152\/ajpheart.00506.2012"},{"key":"2147_CR32","doi-asserted-by":"crossref","unstructured":"Kimura H (2016) Hydrogen polysulfide (H2Sn) signaling along with hydrogen sulfide (H2S) and nitric oxide (NO). J Neural Transm (Vienna) 123:1235\u20131245","DOI":"10.1007\/s00702-016-1600-z"},{"key":"2147_CR33","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1152\/jn.1993.70.1.81","volume":"70","author":"SB Kombian","year":"1993","unstructured":"Kombian SB, Reiffenstein RJ, Colmers WF (1993) The actions of hydrogen sulfide on dorsal raphe serotonergic neurons in vitro. J Neurophysiol 70:81\u201396","journal-title":"J Neurophysiol"},{"key":"2147_CR34","doi-asserted-by":"publisher","first-page":"1641","DOI":"10.1152\/jn.00252.2015","volume":"114","author":"M Kuksis","year":"2015","unstructured":"Kuksis M, Ferguson AV (2015) Actions of a hydrogen sulfide donor (NaHS) on transient sodium, persistent sodium, and voltage-gated calcium currents in neurons of the subfornical organ. J Neurophysiol 114:1641\u20131651","journal-title":"J Neurophysiol"},{"key":"2147_CR35","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1007\/s11064-008-9793-7","volume":"34","author":"KH Kulkarni","year":"2009","unstructured":"Kulkarni KH, Monjok EM, Zeyssig R, Kouamou G, Bongmba ON, Opere CA, Njie YF, Ohia SE (2009) Effect of hydrogen sulfide on sympathetic neurotransmission and catecholamine levels in isolated porcine iris-ciliary body. Neurochem Res 34:400\u2013406","journal-title":"Neurochem Res"},{"key":"2147_CR36","doi-asserted-by":"crossref","unstructured":"Lee SR, Nilius B, Han J (2018) Gaseous signaling molecules in cardiovascular function: from mechanisms to clinical translation. Rev Physiol Biochem Pharmacol","DOI":"10.1007\/112_2017_7"},{"key":"2147_CR37","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1002\/glia.20362","volume":"54","author":"SW Lee","year":"2006","unstructured":"Lee SW, Hu YS, Hu LF, Lu Q, Dawe GS, Moore PK, Wong PT, Bian JS (2006) Hydrogen sulphide regulates calcium homeostasis in microglial cells. Glia 54:116\u2013124","journal-title":"Glia"},{"key":"2147_CR38","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1152\/japplphysiol.00793.2005","volume":"100","author":"CW Leffler","year":"2006","unstructured":"Leffler CW, Parfenova H, Jaggar JH, Wang R (2006) Carbon monoxide and hydrogen sulfide: gaseous messengers in cerebrovascular circulation. J Appl Physiol (1985) 100:1065\u20131076","journal-title":"J Appl Physiol (1985)"},{"key":"2147_CR39","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.tips.2007.11.003","volume":"29","author":"L Li","year":"2008","unstructured":"Li L, Moore PK (2008) Putative biological roles of hydrogen sulfide in health and disease: a breath of not so fresh air? Trends Pharmacol Sci 29:84\u201390","journal-title":"Trends Pharmacol Sci"},{"key":"2147_CR40","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1146\/annurev-pharmtox-010510-100505","volume":"51","author":"L Li","year":"2011","unstructured":"Li L, Rose P, Moore PK (2011) Hydrogen sulfide and cell signaling. Annu Rev Pharmacol Toxicol 51:169\u2013187","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"2147_CR41","doi-asserted-by":"publisher","first-page":"20274","DOI":"10.1074\/jbc.M000930200","volume":"275","author":"JD Machado","year":"2000","unstructured":"Machado JD, Segura F, Brioso MA, Borges R (2000) Nitric oxide modulates a late step of exocytosis. J Biol Chem 275:20274\u201320279","journal-title":"J Biol Chem"},{"key":"2147_CR42","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1113\/jphysiol.1985.sp015817","volume":"367","author":"A Marty","year":"1985","unstructured":"Marty A, Neher E (1985) Potassium channels in cultured bovine adrenal chromaffin cells. J Physiol 367:117\u2013141","journal-title":"J Physiol"},{"key":"2147_CR43","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1038\/35000001","volume":"2","author":"M Montero","year":"2000","unstructured":"Montero M, Alonso MT, Carnicero E, Cuchillo-Ib\u00e1\u00f1ez I, Albillos A, Garc\u00eda AG, Garc\u00eda-Sancho J, Alvarez J (2000) Chromaffin-cell stimulation triggers fast millimolar mitochondrial Ca2+ transients that modulate secretion. Nat Cell Biol 2:57\u201361","journal-title":"Nat Cell Biol"},{"key":"2147_CR44","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/j.tips.2003.10.007","volume":"24","author":"PK Moore","year":"2003","unstructured":"Moore PK, Bhatia M, Moochhala S (2003) Hydrogen sulfide: from the smell of the past to the mediator of the future? Trends Pharmacol Sci 24:609\u2013611","journal-title":"Trends Pharmacol Sci"},{"key":"2147_CR45","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/0922-4106(93)90033-6","volume":"246","author":"MA Moro","year":"1993","unstructured":"Moro MA, Michelena P, Sanchez-Garcia P, Palmer R, Moncada S, Garcia AG (1993) Activation of adrenal medullary L-arginine: nitric oxide pathway by stimuli which induce the release of catecholamines. Eur J Pharmacol 246:213\u2013218","journal-title":"Eur J Pharmacol"},{"key":"2147_CR46","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1161\/CIRCRESAHA.111.240242","volume":"109","author":"AK Mustafa","year":"2011","unstructured":"Mustafa AK, Sikka G, Gazi SK, Steppan J, Jung SM, Bhunia AK, Barodka VM, Gazi FK, Barrow RK, Wang R, Amzel LM, Berkowitz DE, Snyder SH (2011) Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels. Circ Res 109:1259\u20131268","journal-title":"Circ Res"},{"key":"2147_CR47","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1096\/fj.03-1052fje","volume":"18","author":"Y Nagai","year":"2004","unstructured":"Nagai Y, Tsugane M, Oka J, Kimura H (2004) Hydrogen sulfide induces calcium waves in astrocytes. FASEB J 18:557\u2013559","journal-title":"FASEB J"},{"key":"2147_CR48","doi-asserted-by":"publisher","first-page":"1962","DOI":"10.1007\/s11064-009-9984-x","volume":"34","author":"CA Opere","year":"2009","unstructured":"Opere CA, Monjok EM, Kulkarni KH, Njie YF, Ohia SE (2009) Regulation of [3H] D-aspartate release from mammalian isolated retinae by hydrogen sulfide. Neurochem Res 34:1962\u20131968","journal-title":"Neurochem Res"},{"key":"2147_CR49","doi-asserted-by":"publisher","first-page":"81","DOI":"10.2174\/1874467208666150507094537","volume":"8","author":"JF Padin","year":"2015","unstructured":"Padin JF, Fernandez-Morales JC, de Diego AM, Garcia AG (2015) Calcium Channel subtypes and exocytosis in chromaffin cells at early life. Curr Mol Pharmacol 8:81\u201386","journal-title":"Curr Mol Pharmacol"},{"key":"2147_CR50","doi-asserted-by":"publisher","first-page":"21972","DOI":"10.1073\/pnas.0908047106","volume":"106","author":"A Papapetropoulos","year":"2009","unstructured":"Papapetropoulos A, Pyriochou A, Altaany Z, Yang G, Marazioti A, Zhou Z, Jeschke MG, Branski LK, Herndon DN, Wang R, Szabo C (2009) Hydrogen sulfide is an endogenous stimulator of angiogenesis. Proc Natl Acad Sci U S A 106:21972\u201321977","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2147_CR51","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1038\/nrm3391","volume":"13","author":"BD Paul","year":"2012","unstructured":"Paul BD, Snyder SH (2012) H2S signalling through protein sulfhydration and beyond. Nat Rev Mol Cell Biol 13:499\u2013507","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2147_CR52","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1089\/ars.2011.4359","volume":"17","author":"C Peers","year":"2012","unstructured":"Peers C, Bauer CC, Boyle JP, Scragg JL, Dallas ML (2012) Modulation of ion channels by hydrogen sulfide. Antioxid Redox Signal 17:95\u2013105","journal-title":"Antioxid Redox Signal"},{"key":"2147_CR53","doi-asserted-by":"crossref","unstructured":"Rizzuto R, Marchi S, Bonora M, Aguiari P, Bononi A, De Stefani D, Giorgi C, Leo S, Rimessi A, Siviero R, Zecchini E, Pinton P (2009) Ca2+ transfer from the ER to mitochondria: when, how and why. Biochim Biophys Acta 1787:1342\u20131351","DOI":"10.1016\/j.bbabio.2009.03.015"},{"key":"2147_CR54","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/bs.mie.2014.11.014","volume":"554","author":"P Rose","year":"2015","unstructured":"Rose P, Dymock BW, Moore PK (2015) GYY4137, a novel water-soluble, H2S-releasing molecule. Methods Enzymol 554:143\u2013167","journal-title":"Methods Enzymol"},{"key":"2147_CR55","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.1007\/s11064-015-1784-x","volume":"41","author":"A Salvi","year":"2016","unstructured":"Salvi A, Bankhele P, Jamil JM, Kulkarni-Chitnis M, Njie-Mbye YF, Ohia SE, Opere CA (2016) Pharmacological actions of hydrogen sulfide donors on sympathetic neurotransmission in the bovine anterior uvea, in vitro. Neurochem Res 41:1020\u20131028","journal-title":"Neurochem Res"},{"key":"2147_CR56","doi-asserted-by":"crossref","unstructured":"Seidler NW, Jona I, Vegh M, Martonosi A (1989) Cyclopiazonic acid is a specific inhibitor of the Ca2+-ATPase of sarcoplasmic reticulum. J Biol Chem 264:17816\u201317823","DOI":"10.1016\/S0021-9258(19)84646-X"},{"key":"2147_CR57","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1007\/s00424-009-0737-0","volume":"459","author":"GF Sitdikova","year":"2010","unstructured":"Sitdikova GF, Weiger TM, Hermann A (2010) Hydrogen sulfide increases calcium-activated potassium (BK) channel activity of rat pituitary tumor cells. Pflugers Arch 459:389\u2013397","journal-title":"Pflugers Arch"},{"key":"2147_CR58","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1038\/nrd2425","volume":"6","author":"C Szabo","year":"2007","unstructured":"Szabo C (2007) Hydrogen sulphide and its therapeutic potential. Nat Rev Drug Discov 6:917\u2013935","journal-title":"Nat Rev Drug Discov"},{"key":"2147_CR59","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1111\/j.1440-1681.2010.05351.x","volume":"37","author":"G Tang","year":"2010","unstructured":"Tang G, Wu L, Wang R (2010) Interaction of hydrogen sulfide with ion channels. Clin Exp Pharmacol Physiol 37:753\u2013763","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"2147_CR60","doi-asserted-by":"publisher","first-page":"C792","DOI":"10.1152\/ajpcell.00600.2008","volume":"296","author":"L Tapia","year":"2009","unstructured":"Tapia L, Garcia-Eguiagaray J, Garcia AG, Gandia L (2009) Preconditioning stimuli that augment chromaffin cell secretion. Am J Physiol Cell Physiol 296:C792\u2013C800","journal-title":"Am J Physiol Cell Physiol"},{"key":"2147_CR61","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.resp.2010.05.016","volume":"172","author":"V Telezhkin","year":"2010","unstructured":"Telezhkin V, Brazier SP, Cayzac SH, Wilkinson WJ, Riccardi D, Kemp PJ (2010) Mechanism of inhibition by hydrogen sulfide of native and recombinant BKCa channels. Respir Physiol Neurobiol 172:169\u2013178","journal-title":"Respir Physiol Neurobiol"},{"key":"2147_CR62","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1016\/j.phrs.2016.09.006","volume":"113","author":"L Testai","year":"2016","unstructured":"Testai L, Marino A, Piano I, Brancaleone V, Tomita K, Di Cesare Mannelli L, Martelli A, Citi V, Breschi MC, Levi R, Gargini C, Bucci M, Cirino G, Ghelardini C, Calderone V (2016) The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia\/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress. Pharmacol Res 113:290\u2013299","journal-title":"Pharmacol Res"},{"key":"2147_CR63","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1096\/fj.01-0630com","volume":"16","author":"C Villalobos","year":"2002","unstructured":"Villalobos C, Nunez L, Montero M, Garcia AG, Alonso MT, Chamero P, Alvarez J, Garcia-Sancho J (2002) Redistribution of Ca2+ among cytosol and organella during stimulation of bovine chromaffin cells. FASEB J 16:343\u2013353","journal-title":"FASEB J"},{"issue":"Pt 2","key":"2147_CR64","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1111\/j.1469-7793.1999.0421v.x","volume":"516","author":"M Villarroya","year":"1999","unstructured":"Villarroya M, Olivares R, Ruiz A, Cano-Abad MF, de Pascual R, Lomax RB, Lopez MG, Mayorgas I, Gandia L, Garcia AG (1999) Voltage inactivation of Ca2+ entry and secretion associated with N- and P\/Q-type but not L-type Ca2+ channels of bovine chromaffin cells. J Physiol 516(Pt 2):421\u2013432","journal-title":"J Physiol"},{"key":"2147_CR65","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1089\/ars.2011.4310","volume":"17","author":"V Vitvitsky","year":"2012","unstructured":"Vitvitsky V, Kabil O, Banerjee R (2012) High turnover rates for hydrogen sulfide allow for rapid regulation of its tissue concentrations. Antioxid Redox Signal 17:22\u201331","journal-title":"Antioxid Redox Signal"},{"key":"2147_CR66","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1126\/science.8235626","volume":"262","author":"L Ruden von","year":"1993","unstructured":"von Ruden L, Neher E (1993) A Ca-dependent early step in the release of catecholamines from adrenal chromaffin cells. Science 262:1061\u20131065","journal-title":"Science"},{"key":"2147_CR67","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1089\/ars.2009.2938","volume":"12","author":"R Wang","year":"2010","unstructured":"Wang R (2010) Hydrogen sulfide: the third gasotransmitter in biology and medicine. Antioxid Redox Signal 12:1061\u20131064","journal-title":"Antioxid Redox Signal"},{"key":"2147_CR68","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1152\/physrev.00017.2011","volume":"92","author":"R Wang","year":"2012","unstructured":"Wang R (2012) Physiological implications of hydrogen sulfide: a whiff exploration that blossomed. Physiol Rev 92:791\u2013896","journal-title":"Physiol Rev"},{"key":"2147_CR69","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1124\/jpet.107.133538","volume":"324","author":"GD Webb","year":"2008","unstructured":"Webb GD, Lim LH, Oh VM, Yeo SB, Cheong YP, Ali MY, El Oakley R, Lee CN, Wong PS, Caleb MG, Salto-Tellez M, Bhatia M, Chan ES, Taylor EA, Moore PK (2008) Contractile and vasorelaxant effects of hydrogen sulfide and its biosynthesis in the human internal mammary artery. J Pharmacol Exp Ther 324:876\u2013882","journal-title":"J Pharmacol Exp Ther"},{"key":"2147_CR70","doi-asserted-by":"publisher","first-page":"3055","DOI":"10.1113\/jphysiol.2011.206706","volume":"589","author":"WJ Wilkinson","year":"2011","unstructured":"Wilkinson WJ, Kemp PJ (2011) Carbon monoxide: an emerging regulator of ion channels. J Physiol 589:3055\u20133062","journal-title":"J Physiol"},{"key":"2147_CR71","first-page":"714756","volume":"2015","author":"YX Zhang","year":"2015","unstructured":"Zhang YX, Hu KD, Lv K, Li YH, Hu LY, Zhang XQ, Ruan L, Liu YS, Zhang H (2015) The hydrogen sulfide donor NaHS delays programmed cell death in barley aleurone layers by acting as an antioxidant. Oxidative Med Cell Longev 2015:714756","journal-title":"Oxidative Med Cell Longev"},{"key":"2147_CR72","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1113\/jphysiol.1993.sp019813","volume":"469","author":"Z Zhou","year":"1993","unstructured":"Zhou Z, Neher E (1993) Mobile and immobile calcium buffers in bovine adrenal chromaffin cells. J Physiol 469:245\u2013273","journal-title":"J Physiol"},{"key":"2147_CR73","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.tox.2012.07.008","volume":"302","author":"D Zhu","year":"2012","unstructured":"Zhu D, Yu X, Sun J, Li J, Ma X, Yao W (2012) H2S induces catecholamine secretion in rat adrenal chromaffin cells. Toxicology 302:40\u201343","journal-title":"Toxicology"}],"container-title":["Pfl\u00fcgers Archiv - European Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00424-018-2147-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-018-2147-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-018-2147-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,21]],"date-time":"2022-08-21T15:01:04Z","timestamp":1661094064000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00424-018-2147-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,2]]},"references-count":73,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["2147"],"URL":"https:\/\/doi.org\/10.1007\/s00424-018-2147-7","relation":{},"ISSN":["0031-6768","1432-2013"],"issn-type":[{"value":"0031-6768","type":"print"},{"value":"1432-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,2]]},"assertion":[{"value":"30 October 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 May 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}