{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:02:06Z","timestamp":1740106926691,"version":"3.37.3"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T00:00:00Z","timestamp":1646956800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T00:00:00Z","timestamp":1646956800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pflugers Arch - Eur J Physiol"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s00424-022-02677-9","type":"journal-article","created":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T06:02:37Z","timestamp":1646978557000},"page":"603-612","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Determinants of hypokalemia following hypertonic sodium bicarbonate infusion"],"prefix":"10.1007","volume":"474","author":[{"given":"Horacio J.","family":"Adrogu\u00e9","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed A.","family":"Awan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5436-1512","authenticated-orcid":false,"given":"Nicolaos E.","family":"Madias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,3,11]]},"reference":[{"key":"2677_CR1","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1016\/0002-9343(81)90182-0","volume":"71","author":"HJ Adrogu\u00e9","year":"1981","unstructured":"Adrogu\u00e9 HJ, Madias NE (1981) Changes in plasma potassium concentration during acute acid-base disturbances. Am J Med 71:456\u2013467","journal-title":"Am J Med"},{"key":"2677_CR2","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1172\/JCI110841","volume":"71","author":"HJ Adrogu\u00e9","year":"1983","unstructured":"Adrogu\u00e9 HJ, Brensilver J, Cohen JJ, Madias NE (1983) Influence of steady-state alterations in acid-base equilibrium on the fate of administered bicarbonate in the dog. J Clin Invest 71:867\u2013883","journal-title":"J Clin Invest"},{"key":"2677_CR3","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1159\/000501190","volume":"50","author":"HJ Adrogu\u00e9","year":"2019","unstructured":"Adrogu\u00e9 HJ, Mandayam S, Tighiouart H, Madias NE (2019) Osmotic and nonosmotic sodium storage during acute hypertonic sodium loading. Am J Nephrol 50:11\u201318","journal-title":"Am J Nephrol"},{"key":"2677_CR4","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1159\/000506274","volume":"51","author":"HJ Adrogu\u00e9","year":"2020","unstructured":"Adrogu\u00e9 HJ, Awan AA, Madias NE (2020) Sodium fate after sodium bicarbonate infusion: influence of altered acid-base status. Am J Nephrol 51:182\u2013191","journal-title":"Am J Nephrol"},{"key":"2677_CR5","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1007\/BF00583376","volume":"406","author":"HJ Adrogu\u00e9","year":"1986","unstructured":"Adrogu\u00e9 HJ, Madias NE (1986) Renal acidification during chronic hypercapnia in the conscious dog. Pflugers Arch 406:520\u2013528","journal-title":"Pflugers Arch"},{"key":"2677_CR6","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/B978-0-323-47794-9.00010-X","volume-title":"National Kidney Foundation\u2019s Primer on Kidney Diseases","author":"M Allon","year":"2018","unstructured":"Allon M (2018) Disorders of potassium balance. In: Gilbert SJ, Weiner DE (eds) National Kidney Foundation\u2019s Primer on Kidney Diseases, 7th edn. Elsevier, Philadelphia, pp 97\u2013106","edition":"7"},{"key":"2677_CR7","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1016\/S0272-6386(96)90460-6","volume":"28","author":"M Allon","year":"1996","unstructured":"Allon M, Shanklin N (1996) Effect of bicarbonate administration on plasma potassium in dialysis patients: interactions with insulin and albuterol. Am J Kidney Dis 28:508\u2013514","journal-title":"Am J Kidney Dis"},{"key":"2677_CR8","doi-asserted-by":"publisher","first-page":"1981","DOI":"10.1681\/ASN.2011040414","volume":"22","author":"PS Aronson","year":"2011","unstructured":"Aronson PS, Giebisch G (2011) Effects of pH on potassium: new explanations for old observations. J Am Soc Nephrol 22:1981\u20131989","journal-title":"J Am Soc Nephrol"},{"key":"2677_CR9","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1038\/ki.1992.51","volume":"41","author":"A Blumberg","year":"1992","unstructured":"Blumberg A, Weidmann P, Ferrari P (1992) Effect of prolonged bicarbonate administration on plasma potassium in terminal renal failure. Kidney Int 41:369\u2013374","journal-title":"Kidney Int"},{"key":"2677_CR10","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1152\/ajplegacy.1963.204.5.765","volume":"204","author":"EB Brown Jr","year":"1963","unstructured":"Brown EB Jr, Goott B (1963) Intracellular hydrogen ion changes and potassium movement. Am J Physiol 204:765\u2013770","journal-title":"Am J Physiol"},{"key":"2677_CR11","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1172\/JCI107580","volume":"53","author":"RC De Sousa","year":"1974","unstructured":"De Sousa RC, Harrington JT, Ricanati ES, Shelkrot JW, Schwartz WB (1974) Renal regulation of acid-base equilibrium during chronic administration of mineral acid. J Clin Invest 53:465\u2013476","journal-title":"J Clin Invest"},{"key":"2677_CR12","unstructured":"Elkinton JR, Danowsky TS (1955) The body fluids. The Williams & Wilkins Company, Baltimore, p 85"},{"key":"2677_CR13","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1085\/jgp.17.5.629","volume":"17","author":"WO Fenn","year":"1934","unstructured":"Fenn WO, Cobb DM (1934) The potassium equilibrium in muscle. J Gen Physiol 17:629\u2013656","journal-title":"J Gen Physiol"},{"key":"2677_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/ki.1975.69","volume":"8","author":"FJ Gennari","year":"1975","unstructured":"Gennari FJ, Cohen JJ (1975) Role of the kidney in potassium homeostasis: lessons from acid-base disturbances. Kidney Int 8:1\u20135","journal-title":"Kidney Int"},{"key":"2677_CR15","doi-asserted-by":"publisher","first-page":"1722","DOI":"10.1172\/JCI106973","volume":"51","author":"FJ Gennari","year":"1972","unstructured":"Gennari FJ, Goldstein MB, Schwartz WB (1972) The nature of the renal adaptation to chronic hypocapnia. J Clin Invest 51:1722\u20131730","journal-title":"J Clin Invest"},{"key":"2677_CR16","first-page":"297","volume":"17","author":"R Gutierrez","year":"1991","unstructured":"Gutierrez R, Schlessinger F, Oster JR et al (1991) Effect of hypertonic versus isotonic sodium bicarbonate on plasma potassium concentration in patients with end-stage renal disease. Miner Electrolyte Metab 17:297\u2013302","journal-title":"Miner Electrolyte Metab"},{"key":"2677_CR17","first-page":"1581","volume-title":"Strauss and Welt\u2019s Diseases of the Kidney","author":"RT Kunau Jr","year":"1979","unstructured":"Kunau RT Jr, Stein JH (1979) Disorders of potassium metabolism. In: Earley LE, Gottschalk CW (eds) Strauss and Welt\u2019s Diseases of the Kidney. Little, Brown and Company, Boston, pp 1581\u20131638"},{"key":"2677_CR18","first-page":"F283","volume":"238","author":"NE Madias","year":"1980","unstructured":"Madias NE, Adrogu\u00e9 HJ, Cohen JJ (1980) Maladaptive renal response to secondary hypercapnia in chronic metabolic alkalosis. Am J Physiol 238:F283\u2013F289","journal-title":"Am J Physiol"},{"key":"2677_CR19","doi-asserted-by":"publisher","first-page":"F30","DOI":"10.1152\/ajpcell.1979.236.1.C30","volume":"236","author":"NE Madias","year":"1979","unstructured":"Madias NE, Adrogu\u00e9 HJ, Cohen JJ, Schwartz WB (1979) Effect of natural variations in PaCO2 on plasma [HCO3-] in dogs: a redefinition of normal. Am J Physiol 236:F30\u2013F35","journal-title":"Am J Physiol"},{"key":"2677_CR20","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1152\/ajplegacy.1970.218.4.1201","volume":"218","author":"DL Makoff","year":"1970","unstructured":"Makoff DL, Da Silva JA, Rosenbaum BJ, Levy SE, Maxwell MH (1970) Hypertonic expansion: acid-base and electrolyte changes. Am J Physiol 218:1201\u20131207","journal-title":"Am J Physiol"},{"key":"2677_CR21","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.2215\/CJN.08580813","volume":"10","author":"BF Palmer","year":"2015","unstructured":"Palmer BF (2015) Regulation of potassium homeostasis. Clin J Am Soc Nephrol 10:1050\u20131060","journal-title":"Clin J Am Soc Nephrol"},{"key":"2677_CR22","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/S0021-9258(18)64885-9","volume":"225","author":"ME Rubini","year":"1957","unstructured":"Rubini ME, Wolf AV (1957) Refractometric determination of total solids and water of serum and urine. J Biol Chem 225:869\u2013876","journal-title":"J Biol Chem"},{"key":"2677_CR23","first-page":"1629","volume-title":"Seldin and Giebisch\u2019s The Kidney Physiology and Pathophysiology","author":"V Sahni","year":"2013","unstructured":"Sahni V, Zmurczyk A, Rosa RM (2013) Extrarenal potassium metabolism. In: Alpern RJ, Moe OW, Caplan M (eds) Seldin and Giebisch\u2019s The Kidney Physiology and Pathophysiology, 5th edn. Elsevier, Amsterdam, pp 1629\u20131657","edition":"5"},{"key":"2677_CR24","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1152\/jappl.1965.20.4.767","volume":"20","author":"WB Schwartz","year":"1965","unstructured":"Schwartz WB, Silverman L (1965) A large environmental chamber for the study of hypercapnia and hypoxia. J Appl Physiol 20:767\u2013774","journal-title":"J Appl Physiol"},{"key":"2677_CR25","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1172\/JCI105143","volume":"44","author":"WB Schwartz","year":"1965","unstructured":"Schwartz WB, Brackett NC Jr, Cohen JJ (1965) The response of extracellular hydrogen ion concentration to graded degrees of chronic hypercapnia: the physiologic limits of the defense of pH. J Clin Invest 44:291\u2013301","journal-title":"J Clin Invest"},{"key":"2677_CR26","doi-asserted-by":"publisher","first-page":"1795","DOI":"10.1172\/JCI103234","volume":"34","author":"RC Swan","year":"1955","unstructured":"Swan RC, Axelrod DR, Seip M, Pitts RF (1955) Distribution of sodium bicarbonate infused into nephrectomized dogs. J Clin Invest 34:1795\u20131801","journal-title":"J Clin Invest"},{"key":"2677_CR27","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1172\/JCI102739","volume":"32","author":"M Walser","year":"1953","unstructured":"Walser M, Seldin DW, Grollman A (1953) An evaluation of radiosulfate for the determination of the volume of extracellular fluid in man and dogs. J Clin Invest 32:299\u2013311","journal-title":"J Clin Invest"}],"container-title":["Pfl\u00fcgers Archiv - European Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-022-02677-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00424-022-02677-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-022-02677-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T18:17:29Z","timestamp":1700331449000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00424-022-02677-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,11]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["2677"],"URL":"https:\/\/doi.org\/10.1007\/s00424-022-02677-9","relation":{},"ISSN":["0031-6768","1432-2013"],"issn-type":[{"type":"print","value":"0031-6768"},{"type":"electronic","value":"1432-2013"}],"subject":[],"published":{"date-parts":[[2022,3,11]]},"assertion":[{"value":"21 October 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 February 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Animal experiments conformed to internationally accepted standards and had been approved by the institutional review body for animal research of Tufts-New England Medical Center.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}