{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T03:41:03Z","timestamp":1788234063509,"version":"build-2803163510"},"reference-count":175,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pflugers Arch - Eur J Physiol"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1007\/s00424-023-02891-z","type":"journal-article","created":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T03:02:01Z","timestamp":1701399721000},"page":"163-177","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The T-type calcium channelosome"],"prefix":"10.1007","volume":"476","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0040-1109","authenticated-orcid":false,"given":"Norbert","family":"Weiss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0644-9066","authenticated-orcid":false,"given":"Gerald W.","family":"Zamponi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,12,1]]},"reference":[{"key":"2891_CR1","doi-asserted-by":"publisher","first-page":"H58","DOI":"10.1152\/ajpheart.00476.2012","volume":"304","author":"RR Abd El-Rahman","year":"2013","unstructured":"Abd El-Rahman RR, Harraz OF, Brett SE, Anfinogenova Y, Mufti RE, Goldman D, Welsh DG (2013) Identification of L- and T-type Ca2+ channels in rat cerebral arteries: role in myogenic tone development. Am J Physiol Heart Circ Physiol 304:H58\u2013H71. https:\/\/doi.org\/10.1152\/ajpheart.00476.2012","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2891_CR2","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/1478-811X-9-22","volume":"9","author":"DR Adams","year":"2011","unstructured":"Adams DR, Ron D, Kiely PA (2011) RACK1, A multifaceted scaffolding protein: structure and function. Cell Commun Signal 9:22. https:\/\/doi.org\/10.1186\/1478-811X-9-22","journal-title":"Cell Commun Signal"},{"key":"2891_CR3","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1007\/s00424-023-02808-w","volume":"475","author":"AM Alaklabi","year":"2023","unstructured":"Alaklabi AM, Gambeta E, Zamponi GW (2023) Electrophysiological characterization of a CaV3.1 calcium channel mutation linked to trigeminal neuralgia. Pflugers Arch 475:711\u2013718. https:\/\/doi.org\/10.1007\/s00424-023-02808-w","journal-title":"Pflugers Arch"},{"key":"2891_CR4","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1038\/nn.2493","volume":"13","author":"D Anderson","year":"2010","unstructured":"Anderson D, Mehaffey WH, Iftinca M, Rehak R, Engbers JD, Hameed S, Zamponi GW, Turner RW (2010) Regulation of neuronal activity by Cav3-Kv4 channel signaling complexes. Nat Neurosci 13:333\u2013337. https:\/\/doi.org\/10.1038\/nn.2493","journal-title":"Nat Neurosci"},{"key":"2891_CR5","doi-asserted-by":"publisher","first-page":"163","DOI":"10.4161\/chan.4.3.11955","volume":"4","author":"D Anderson","year":"2010","unstructured":"Anderson D, Rehak R, Hameed S, Mehaffey WH, Zamponi GW, Turner RW (2010) Regulation of the KV4.2 complex by CaV3.1 calcium channels. Channels (Austin) 4:163\u2013167. https:\/\/doi.org\/10.4161\/chan.4.3.11955","journal-title":"Channels (Austin)"},{"key":"2891_CR6","doi-asserted-by":"publisher","first-page":"34233","DOI":"10.1038\/srep34233","volume":"6","author":"A Andrade","year":"2016","unstructured":"Andrade A, Hope J, Allen A, Yorgan V, Lipscombe D, Pan JQ (2016) A rare schizophrenia risk variant of CACNA1I disrupts CaV3.3 channel activity. Sci Rep 6:34233. https:\/\/doi.org\/10.1038\/srep34233","journal-title":"Sci Rep"},{"key":"2891_CR7","doi-asserted-by":"publisher","first-page":"402","DOI":"10.4161\/chan.3.6.9858","volume":"3","author":"KA Aromolaran","year":"2009","unstructured":"Aromolaran KA, Benzow KA, Cribbs LL, Koob MD, Piedras-Renter\u00eda ES (2009) Kelch-like 1 protein upregulates T-type currents by an actin-F dependent increase in \u03b1(1H) channels via the recycling endosome. Channels (Austin) 3:402\u2013412. https:\/\/doi.org\/10.4161\/chan.3.6.9858","journal-title":"Channels (Austin)"},{"key":"2891_CR8","doi-asserted-by":"publisher","first-page":"C1353","DOI":"10.1152\/ajpcell.00235.2009","volume":"298","author":"KA Aromolaran","year":"2010","unstructured":"Aromolaran KA, Benzow KA, Cribbs LL, Koob MD, Piedras-Renter\u00eda ES (2010) T-type current modulation by the actin-binding protein Kelch-like 1. Am J Physiol Cell Physiol 298:C1353\u2013C1362. https:\/\/doi.org\/10.1152\/ajpcell.00235.2009","journal-title":"Am J Physiol Cell Physiol"},{"key":"2891_CR9","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1016\/j.neuroscience.2006.12.046","volume":"145","author":"KA Aromolaran","year":"2007","unstructured":"Aromolaran KA, Benzow KA, Koob MD, Piedras-Renter\u00eda ES (2007) The Kelch-like protein 1 modulates P\/Q-type calcium current density. Neuroscience 145:841\u2013850. https:\/\/doi.org\/10.1016\/j.neuroscience.2006.12.046","journal-title":"Neuroscience"},{"key":"2891_CR10","doi-asserted-by":"publisher","unstructured":"Arteaga-Tlecuitl R, Sanchez-Sandoval AL, Ramirez-Cordero BE, Rosendo-Pineda MJ, Vaca L, Gomora JC (2018) Increase of CaV3 channel activity induced by HVA \u03b21b-subunit is not mediated by a physical interaction. BMC Res Notes 11. https:\/\/doi.org\/10.1186\/s13104-018-3917-1","DOI":"10.1186\/s13104-018-3917-1"},{"key":"2891_CR11","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s13041-017-0317-8","volume":"10","author":"H Asmara","year":"2017","unstructured":"Asmara H, Micu I, Rizwan AP, Sahu G, Simms BA, Zhang FX, Engbers JDT, Stys PK, Zamponi GW, Turner RW (2017) A T-type channel-calmodulin complex triggers \u03b1CaMKII activation. Mol Brain 10:37. https:\/\/doi.org\/10.1186\/s13041-017-0317-8","journal-title":"Mol Brain"},{"key":"2891_CR12","doi-asserted-by":"publisher","first-page":"13823","DOI":"10.1073\/pnas.1105115108","volume":"108","author":"S Astori","year":"2011","unstructured":"Astori S, Wimmer RD, Prosser HM, Corti C, Corsi M, Liaudet N, Volterra A, Franken P, Adelman JP, L\u00fcthi A (2011) The Ca(V)3.3 calcium channel is the major sleep spindle pacemaker in thalamus. Proc Natl Acad Sci USA 108:13823\u201313828. https:\/\/doi.org\/10.1073\/pnas.1105115108","journal-title":"Proc Natl Acad Sci USA"},{"key":"2891_CR13","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1007\/s10059-010-0106-z","volume":"30","author":"J Bae","year":"2010","unstructured":"Bae J, Suh EJ, Lee C (2010) Interaction of T-type calcium channel Ca(V)3.3 with the \u03b2-subunit. Mol Cells 30:185\u2013191. https:\/\/doi.org\/10.1007\/s10059-010-0106-z","journal-title":"Mol Cells"},{"key":"2891_CR14","doi-asserted-by":"publisher","first-page":"1839","DOI":"10.1093\/brain\/awab443","volume":"145","author":"D Baez-Nieto","year":"2022","unstructured":"Baez-Nieto D, Allen A, Akers-Campbell S, Yang L, Budnik N, Pupo A, Shin Y-C, Genovese G, Liao M, P\u00e9rez-Palma E, Heyne H, Lal D, Lipscombe D, Pan JQ (2022) Analysing an allelic series of rare missense variants of CACNA1I in a Swedish schizophrenia cohort. Brain 145:1839\u20131853. https:\/\/doi.org\/10.1093\/brain\/awab443","journal-title":"Brain"},{"key":"2891_CR15","doi-asserted-by":"publisher","first-page":"102669","DOI":"10.1016\/j.ceca.2022.102669","volume":"108","author":"M Barghouth","year":"2022","unstructured":"Barghouth M, Ye Y, Karagiannopoulos A, Ma Y, Cowan E, Wu R, Eliasson L, Renstr\u00f6m E, Luan C, Zhang E (2022) The T-type calcium channel CaV3.2 regulates insulin secretion in the pancreatic \u03b2-cell. Cell Calcium 108:102669. https:\/\/doi.org\/10.1016\/j.ceca.2022.102669","journal-title":"Cell Calcium"},{"key":"2891_CR16","doi-asserted-by":"publisher","first-page":"C1694","DOI":"10.1152\/ajpcell.2000.279.6.C1694","volume":"279","author":"PQ Barrett","year":"2000","unstructured":"Barrett PQ, Lu HK, Colbran R, Czernik A, Pancrazio JJ (2000) Stimulation of unitary T-type Ca(2+) channel currents by calmodulin-dependent protein kinase II. Am J Physiol Cell Physiol 279:C1694\u2013C1703. https:\/\/doi.org\/10.1152\/ajpcell.2000.279.6.C1694","journal-title":"Am J Physiol Cell Physiol"},{"key":"2891_CR17","doi-asserted-by":"publisher","first-page":"188","DOI":"10.2174\/1874467208666150507110359","volume":"8","author":"M Ben-Johny","year":"2015","unstructured":"Ben-Johny M, Dick IE, Sang L, Limpitikul WB, Kang PW, Niu J, Banerjee R, Yang W, Babich JS, Issa JB, Lee SR, Namkung H, Li J, Zhang M, Yang PS, Bazzazi H, Adams PJ, Joshi-Mukherjee R, Yue DN, Yue DT (2015) Towards a unified theory of calmodulin regulation (calmodulation) of voltage-gated calcium and sodium channels. Curr Mol Pharmacol 8:188\u2013205. https:\/\/doi.org\/10.2174\/1874467208666150507110359","journal-title":"Curr Mol Pharmacol"},{"key":"2891_CR18","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1085\/jgp.201311153","volume":"143","author":"M Ben-Johny","year":"2014","unstructured":"Ben-Johny M, Yue DT (2014) Calmodulin regulation (calmodulation) of voltage-gated calcium channels. J Gen Physiol 143:679\u2013692. https:\/\/doi.org\/10.1085\/jgp.201311153","journal-title":"J Gen Physiol"},{"key":"2891_CR19","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/978-3-031-08881-0_9","volume-title":"In Voltage-gated calcium channels Eds","author":"M Ben-Johny","year":"2022","unstructured":"Ben-Johny M, Dick IE (2022) In Voltage-gated calcium channels Eds. Springer, pp 217\u2013236"},{"key":"2891_CR20","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.neuron.2008.12.004","volume":"61","author":"KJ Bender","year":"2009","unstructured":"Bender KJ, Trussell LO (2009) Axon initial segment Ca2+ channels influence action potential generation and timing. Neuron 61:259\u2013271. https:\/\/doi.org\/10.1016\/j.neuron.2008.12.004","journal-title":"Neuron"},{"key":"2891_CR21","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1113\/jphysiol.2001.013246","volume":"539","author":"C Berthier","year":"2002","unstructured":"Berthier C, Monteil A, Lory P, Strube C (2002) Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice. J Physiol 539:681\u2013691. https:\/\/doi.org\/10.1113\/jphysiol.2001.013246","journal-title":"J Physiol"},{"key":"2891_CR22","doi-asserted-by":"publisher","first-page":"7627","DOI":"10.1073\/pnas.97.13.7627","volume":"97","author":"P Bijlenga","year":"2000","unstructured":"Bijlenga P, Liu JH, Espinos E, Haenggeli CA, Fischer-Lougheed J, Bader CR, Bernheim L (2000) T-type alpha 1H Ca2+ channels are involved in Ca2+ signaling during terminal differentiation (fusion) of human myoblasts. Proc Natl Acad Sci USA 97:7627\u20137632. https:\/\/doi.org\/10.1073\/pnas.97.13.7627","journal-title":"Proc Natl Acad Sci USA"},{"key":"2891_CR23","doi-asserted-by":"publisher","first-page":"13705","DOI":"10.1073\/pnas.1511740112","volume":"112","author":"I Blesneac","year":"2015","unstructured":"Blesneac I, Chemin J, Bidaud I, Huc-Brandt S, Vandermoere F, Lory P (2015) Phosphorylation of the Cav3.2 T-type calcium channel directly regulates its gating properties. Proc Natl Acad Sci USA 112:13705\u201313710. https:\/\/doi.org\/10.1073\/pnas.1511740112","journal-title":"Proc Natl Acad Sci USA"},{"key":"2891_CR24","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.yjmcc.2013.12.026","volume":"68","author":"S Bryant","year":"2014","unstructured":"Bryant S, Kimura TE, Kong CH, Watson JJ, Chase A, Suleiman MS, James AF, Orchard CH (2014) Stimulation of ICa by basal PKA activity is facilitated by caveolin-3 in cardiac ventricular myocytes. J Mol Cell Cardiol 68:47\u201355. https:\/\/doi.org\/10.1016\/j.yjmcc.2013.12.026","journal-title":"J Mol Cell Cardiol"},{"key":"2891_CR25","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.trsl.2021.01.002","volume":"234","author":"S Cai","year":"2021","unstructured":"Cai S, Gomez K, Moutal A, Khanna R (2021) Targeting T-type\/CaV3.2 channels for chronic pain. Transl Res 234:20\u201330. https:\/\/doi.org\/10.1016\/j.trsl.2021.01.002","journal-title":"Transl Res"},{"key":"2891_CR26","doi-asserted-by":"publisher","first-page":"1376","DOI":"10.1073\/pnas.1715997115","volume":"115","author":"M Campiglio","year":"2018","unstructured":"Campiglio M, Cost\u00e9 de Bagneaux P, Ortner NJ, Tuluc P, Van Petegem F, Flucher BE (2018) STAC proteins associate to the IQ domain of CaV1.2 and inhibit calcium-dependent inactivation. Proc Natl Acad Sci USA 115:1376\u20131381. https:\/\/doi.org\/10.1073\/pnas.1715997115","journal-title":"Proc Natl Acad Sci USA"},{"key":"2891_CR27","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1007\/s00249-007-0138-2","volume":"36","author":"V Carabelli","year":"2007","unstructured":"Carabelli V, Marcantoni A, Comunanza V, Carbone E (2007) Fast exocytosis mediated by T- and L-type channels in chromaffin cells: distinct voltage-dependence but similar Ca2+ -dependence. Eur Biophys J 36:753\u2013762. https:\/\/doi.org\/10.1007\/s00249-007-0138-2","journal-title":"Eur Biophys J"},{"key":"2891_CR28","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1113\/jphysiol.2007.132274","volume":"584","author":"V Carabelli","year":"2007","unstructured":"Carabelli V, Marcantoni A, Comunanza V, de Luca A, D\u00edaz J, Borges R, Carbone E (2007) Chronic hypoxia up-regulates alpha1H T-type channels and low-threshold catecholamine secretion in rat chromaffin cells. J Physiol 584:149\u2013165. https:\/\/doi.org\/10.1113\/jphysiol.2007.132274","journal-title":"J Physiol"},{"key":"2891_CR29","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1007\/s00424-014-1489-z","volume":"466","author":"E Carbone","year":"2014","unstructured":"Carbone E, Calorio C, Vandael DH (2014) T-type channel-mediated neurotransmitter release. Pflugers Arch 466:677\u2013687. https:\/\/doi.org\/10.1007\/s00424-014-1489-z","journal-title":"Pflugers Arch"},{"key":"2891_CR30","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1080\/19336950.2019.1614415","volume":"13","author":"MT Carter","year":"2019","unstructured":"Carter MT, McMillan HJ, Tomin A, Weiss N (2019) Compound heterozygous CACNA1H mutations associated with severe congenital amyotrophy. Channels (Austin) 13:153\u2013161. https:\/\/doi.org\/10.1080\/19336950.2019.1614415","journal-title":"Channels (Austin)"},{"key":"2891_CR31","doi-asserted-by":"publisher","first-page":"1759","DOI":"10.1007\/s00424-013-1411-0","volume":"466","author":"M Cazade","year":"2014","unstructured":"Cazade M, Bidaud I, Hansen PB, Lory P, Chemin J (2014) 5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone. Pfl\u00fcgers Archiv - Eur J Physiol 466:1759\u20131768. https:\/\/doi.org\/10.1007\/s00424-013-1411-0","journal-title":"Pfl\u00fcgers Archiv - Eur J Physiol"},{"key":"2891_CR32","doi-asserted-by":"publisher","first-page":"1998","DOI":"10.1093\/brain\/awy145","volume":"141","author":"J Chemin","year":"2018","unstructured":"Chemin J, Siquier-Pernet K, Nicouleau M, Barcia G, Ahmad A, Medina-Cano D, Hanein S, Altin N, Hubert L, Bole-Feysot C, Fourage C, Nitschk\u00e9 P, Thevenon J, Rio M, Blanc P, Vidal C, Bahi-Buisson N, Desguerre I, Munnich A et al (2018) De novo mutation screening in childhood-onset cerebellar atrophy identifies gain-of-function mutations in the CACNA1G calcium channel gene. Brain 141:1998\u20132013. https:\/\/doi.org\/10.1093\/brain\/awy145","journal-title":"Brain"},{"key":"2891_CR33","doi-asserted-by":"publisher","first-page":"20010","DOI":"10.1074\/jbc.M117.807925","volume":"292","author":"J Chemin","year":"2017","unstructured":"Chemin J, Taiakina V, Monteil A, Piazza M, Guan W, Stephens RF, Kitmitto A, Pang ZP, Dolphin AC, Perez-Reyes E, Dieckmann T, Guillemette JG, Spafford JD (2017) Calmodulin regulates Cav3 T-type channels at their gating brake. J Biol Chem 292:20010\u201320031. https:\/\/doi.org\/10.1074\/jbc.M117.807925","journal-title":"J Biol Chem"},{"key":"2891_CR34","doi-asserted-by":"publisher","first-page":"1416","DOI":"10.1126\/science.1089268","volume":"302","author":"CC Chen","year":"2003","unstructured":"Chen CC, Lamping KG, Nuno DW, Barresi R, Prouty SJ, Lavoie JL, Cribbs LL, England SK, Sigmund CD, Weiss RM, Williamson RA, Hill JA, Campbell KP (2003) Abnormal coronary function in mice deficient in alpha1H T-type Ca2+ channels. Science 302:1416\u20131418. https:\/\/doi.org\/10.1126\/science.1089268","journal-title":"Science"},{"key":"2891_CR35","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1186\/s13041-019-0494-8","volume":"12","author":"CSW Choi","year":"2019","unstructured":"Choi CSW, Souza IA, Sanchez-Arias JC, Zamponi GW, Arbour LT, Swayne LA (2019) Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels. Mol. Brain 12:75. https:\/\/doi.org\/10.1186\/s13041-019-0494-8","journal-title":"Brain"},{"key":"2891_CR36","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1111\/j.1601-183X.2006.00268.x","volume":"6","author":"S Choi","year":"2007","unstructured":"Choi S, Na HS, Kim J, Lee J, Lee S, Kim D, Park J, Chen CC, Campbell KP, Shin HS (2007) Attenuated pain responses in mice lacking Ca(V)3.2 T-type channels. Genes Brain Behav 6:425\u2013431. https:\/\/doi.org\/10.1111\/j.1601-183X.2006.00268.x","journal-title":"Genes Brain Behav"},{"key":"2891_CR37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13041-021-00891-7","volume":"15","author":"L Cmarko","year":"2022","unstructured":"Cmarko L, Stringer RN, Jurkovicova-Tarabova B, Vacik T, Lacinova L, Weiss N (2022) Secretory carrier-associated membrane protein 2 (SCAMP2) regulates cell surface expression of T-type calcium channels. Mol Brain 15:1. https:\/\/doi.org\/10.1186\/s13041-021-00891-7","journal-title":"Mol Brain"},{"key":"2891_CR38","doi-asserted-by":"publisher","first-page":"9186","DOI":"10.1523\/JNEUROSCI.3572-15.2018","volume":"38","author":"GS Cottrell","year":"2018","unstructured":"Cottrell GS, Soubrane CH, Hounshell JA, Lin H, Owenson V, Rigby M, Cox PJ, Barker BS, Ottolini M, Ince S, Bauer CC, Perez-Reyes E, Patel MK, Stevens EB, Stephens GJ (2018) CACHD1 is an \u03b12\u03b4-like protein that modulates CaV3 voltage-gated calcium channel activity. J Neurosci 38:9186\u20139201. https:\/\/doi.org\/10.1523\/JNEUROSCI.3572-15.2018","journal-title":"J Neurosci"},{"key":"2891_CR39","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1016\/j.ajhg.2015.09.007","volume":"97","author":"M Coutelier","year":"2015","unstructured":"Coutelier M, Blesneac I, Monteil A, Monin ML, Ando K, Mundwiller E, Brusco A, Le Ber I, Anheim M, Castrioto A, Duyckaerts C, Brice A, Durr A, Lory P, Stevanin G (2015) A recurrent mutation in CACNA1G alters Cav3.1 T-type calcium-channel conduction and causes autosomal-dominant cerebellar ataxia. Am J Hum Genet 97:726\u2013737. https:\/\/doi.org\/10.1016\/j.ajhg.2015.09.007","journal-title":"Am J Hum Genet"},{"key":"2891_CR40","doi-asserted-by":"publisher","first-page":"15419","DOI":"10.1523\/JNEUROSCI.3636-10.2010","volume":"30","author":"SR Crandall","year":"2010","unstructured":"Crandall SR, Govindaiah G, Cox CL (2010) Low-threshold Ca2+ current amplifies distal dendritic signaling in thalamic reticular neurons. J Neurosci 30:15419\u201315429. https:\/\/doi.org\/10.1523\/JNEUROSCI.3636-10.2010","journal-title":"J Neurosci"},{"key":"2891_CR41","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1161\/01.res.83.1.103","volume":"83","author":"LL Cribbs","year":"1998","unstructured":"Cribbs LL, Lee JH, Yang J, Satin J, Zhang Y, Daud A, Barclay J, Williamson MP, Fox M, Rees M, Perez-Reyes E (1998) Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2+ channel gene family. Circ Res 83:103\u2013109. https:\/\/doi.org\/10.1161\/01.res.83.1.103","journal-title":"Circ Res"},{"key":"2891_CR42","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1038\/nn.2124","volume":"11","author":"L Cueni","year":"2008","unstructured":"Cueni L, Canepari M, Luj\u00e1n R, Emmenegger Y, Watanabe M, Bond CT, Franken P, Adelman JP, L\u00fcthi A (2008) T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites. Nat Neurosci 11:683\u2013692. https:\/\/doi.org\/10.1038\/nn.2124","journal-title":"Nat Neurosci"},{"key":"2891_CR43","doi-asserted-by":"publisher","first-page":"1212","DOI":"10.1161\/CIRCULATIONAHA.111.023986","volume":"124","author":"SR Cunha","year":"2011","unstructured":"Cunha SR, Hund TJ, Hashemi S, Voigt N, Li N, Wright P, Koval O, Li J, Gudmundsson H, Gumina RJ, Karck M, Schott JJ, Probst V, Le Marec H, Anderson ME, Dobrev D, Wehrens XH, Mohler PJ (2011) Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation. Circulation 124:1212\u20131222. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.111.023986","journal-title":"Circulation"},{"key":"2891_CR44","doi-asserted-by":"publisher","first-page":"1610","DOI":"10.1016\/j.celrep.2018.10.033","volume":"25","author":"S Dahimene","year":"2018","unstructured":"Dahimene S, Page KM, Kadurin I, Ferron L, Ho DY, Powell GT, Pratt WS, Wilson SW, Dolphin AC (2018) The \u03b12\u03b4-like protein Cachd1 increases N-type calcium currents and cell surface expression and competes with \u03b12\u03b4-1. Cell Rep 25:1610\u20131621.e5. https:\/\/doi.org\/10.1016\/j.celrep.2018.10.033","journal-title":"Cell Rep"},{"key":"2891_CR45","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.ebiom.2016.10.002","volume":"13","author":"G Daniil","year":"2016","unstructured":"Daniil G, Fernandes-Rosa FL, Chemin J, Blesneac I, Beltrand J, Polak M, Jeunemaitre X, Boulkroun S, Amar L, Strom TM, Lory P, Zennaro MC (2016) CACNA1H mutations are associated with different forms of primary aldosteronism. EBioMedicine 13:225\u2013236. https:\/\/doi.org\/10.1016\/j.ebiom.2016.10.002","journal-title":"EBioMedicine"},{"key":"2891_CR46","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1038\/385446a0","volume":"385","author":"M De Waard","year":"1997","unstructured":"De Waard M, Liu H, Walker D, Scott VE, Gurnett CA, Campbell KP (1997) Direct binding of G-protein betagamma complex to voltage-dependent calcium channels. Nature 385:446\u2013450. https:\/\/doi.org\/10.1038\/385446a0","journal-title":"Nature"},{"key":"2891_CR47","doi-asserted-by":"publisher","first-page":"14590","DOI":"10.1073\/pnas.0603945103","volume":"103","author":"SD DePuy","year":"2006","unstructured":"DePuy SD, Yao J, Hu C, McIntire W, Bidaud I, Lory P, Rastinejad F, Gonzalez C, Garrison JC, Barrett PQ (2006) The molecular basis for T-type Ca2+ channel inhibition by G protein beta2gamma2 subunits. Proc Natl Acad Sci USA 103:14590\u201314595. https:\/\/doi.org\/10.1073\/pnas.0603945103","journal-title":"Proc Natl Acad Sci USA"},{"key":"2891_CR48","doi-asserted-by":"publisher","first-page":"13892","DOI":"10.1074\/jbc.M807055200","volume":"284","author":"GH Diering","year":"2009","unstructured":"Diering GH, Church J, Numata M (2009) Secretory carrier membrane protein 2 regulates cell-surface targeting of brain-enriched Na+\/H+ exchanger NHE5. J Biol Chem 284:13892\u201313903. https:\/\/doi.org\/10.1074\/jbc.M807055200","journal-title":"J Biol Chem"},{"key":"2891_CR49","doi-asserted-by":"publisher","first-page":"29263","DOI":"10.1074\/jbc.M313450200","volume":"279","author":"SJ Dubel","year":"2004","unstructured":"Dubel SJ, Altier C, Chaumont S, Lory P, Bourinet E, Nargeot J (2004) Plasma membrane expression of T-type calcium channel alpha(1) subunits is modulated by high voltage-activated auxiliary subunits. J Biol Chem 279:29263\u201329269. https:\/\/doi.org\/10.1074\/jbc.M313450200","journal-title":"J Biol Chem"},{"key":"2891_CR50","doi-asserted-by":"publisher","first-page":"2601","DOI":"10.1073\/pnas.1115024109","volume":"109","author":"JD Engbers","year":"2012","unstructured":"Engbers JD, Anderson D, Asmara H, Rehak R, Mehaffey WH, Hameed S, McKay BE, Kruskic M, Zamponi GW, Turner RW (2012) Intermediate conductance calcium-activated potassium channels modulate summation of parallel fiber input in cerebellar Purkinje cells. Proc Natl Acad Sci USA 109:2601\u20132606. https:\/\/doi.org\/10.1073\/pnas.1115024109","journal-title":"Proc Natl Acad Sci USA"},{"key":"2891_CR51","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1002\/jcp.21075","volume":"212","author":"J Escoffier","year":"2007","unstructured":"Escoffier J, Boisseau S, Serres C, Chen CC, Kim D, Stamboulian S, Shin HS, Campbell KP, De Waard M, Arnoult C (2007) Expression, localization and functions in acrosome reaction and sperm motility of Ca(V)3.1 and Ca(V)3.2 channels in sperm cells: an evaluation from Ca(V)3.1 and Ca(V)3.2 deficient mice. J Cell Physiol 212:753\u2013763. https:\/\/doi.org\/10.1002\/jcp.21075","journal-title":"J Cell Physiol"},{"key":"2891_CR52","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4149\/gpb_2016037","volume":"36","author":"R Felix","year":"2017","unstructured":"Felix R, Weiss N (2017) Ubiquitination and proteasome-mediated degradation of voltage-gated Ca2+ channels and potential pathophysiological implications. Gen Physiol Biophys 36:1\u20135. https:\/\/doi.org\/10.4149\/gpb_2016037","journal-title":"Gen Physiol Biophys"},{"key":"2891_CR53","doi-asserted-by":"publisher","first-page":"21510","DOI":"10.1038\/s41598-020-78488-8","volume":"10","author":"S Feseha","year":"2020","unstructured":"Feseha S, Timic Stamenic T, Wallace D, Tamag C, Yang L, Pan JQ, Todorovic SM (2020) Global genetic deletion of CaV3.3 channels facilitates anaesthetic induction and enhances isoflurane-sparing effects of T-type calcium channel blockers. Sci Rep 10:21510. https:\/\/doi.org\/10.1038\/s41598-020-78488-8","journal-title":"Sci Rep"},{"key":"2891_CR54","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1186\/s13041-020-00697-z","volume":"13","author":"V Ficelova","year":"2020","unstructured":"Ficelova V, Souza IA, Cmarko L, Gandini MA, Stringer RN, Zamponi GW, Weiss N (2020) Functional identification of potential non-canonical N-glycosylation sites within Cav3.2 T-type calcium channels. Mol Brain 13:149. https:\/\/doi.org\/10.1186\/s13041-020-00697-z","journal-title":"Mol Brain"},{"key":"2891_CR55","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.bbrc.2011.01.069","volume":"406","author":"AW Fjorback","year":"2011","unstructured":"Fjorback AW, M\u00fcller HK, Haase J, Raarup MK, Wiborg O (2011) Modulation of the dopamine transporter by interaction with secretory carrier membrane protein 2. Biochem Biophys Res Commun 406:165\u2013170. https:\/\/doi.org\/10.1016\/j.bbrc.2011.01.069","journal-title":"Biochem Biophys Res Commun"},{"key":"2891_CR56","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1016\/j.bbamcr.2018.12.004","volume":"1866","author":"BE Flucher","year":"2019","unstructured":"Flucher BE, Campiglio M (2019) STAC proteins: The missing link in skeletal muscle EC coupling and new regulators of calcium channel function. Biochim Biophys Acta Mol Cell Res 1866:1101\u20131110. https:\/\/doi.org\/10.1016\/j.bbamcr.2018.12.004","journal-title":"Biochim Biophys Acta Mol Cell Res"},{"key":"2891_CR57","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1242\/bio.20135215","volume":"2","author":"F Gacki\u00e8re","year":"2013","unstructured":"Gacki\u00e8re F, Warnier M, Katsogiannou M, Derouiche S, Delcourt P, Dewailly E, Slomianny C, Humez S, Prevarskaya N, Roudbaraki M, Mariot P (2013) Functional coupling between large-conductance potassium channels and Cav3.2 voltage-dependent calcium channels participates in prostate cancer cell growth. Biology Open 2:941\u2013951. https:\/\/doi.org\/10.1242\/bio.20135215","journal-title":"Biology Open"},{"key":"2891_CR58","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s12990-015-0011-8","volume":"11","author":"VM Gadotti","year":"2015","unstructured":"Gadotti VM, Caballero AG, Berger ND, Gladding CM, Chen L, Pfeifer TA, Zamponi GW (2015) Small organic molecule disruptors of Cav3.2 - USP5 interactions reverse inflammatory and neuropathic pain. Mol Pain 11:12. https:\/\/doi.org\/10.1186\/s12990-015-0011-8","journal-title":"Mol Pain"},{"key":"2891_CR59","doi-asserted-by":"publisher","first-page":"2798","DOI":"10.1097\/j.pain.0000000000001669","volume":"160","author":"AS Gaifullina","year":"2019","unstructured":"Gaifullina AS, Lazniewska J, Gerasimova EV, Burkhanova GF, Rzhepetskyy Y, Tomin A, Rivas-Ramirez P, Huang J, Cmarko L, Zamponi GW, Sitdikova GF, Weiss N (2019) A potential role for T-type calcium channels in homocysteinemia-induced peripheral neuropathy. Pain 160:2798\u20132810. https:\/\/doi.org\/10.1097\/j.pain.0000000000001669","journal-title":"Pain"},{"key":"2891_CR60","doi-asserted-by":"publisher","unstructured":"Gambeta E, Gandini MA, Souza IA, Zamponi GW (2022) CaV3.2 calcium channels contribute to trigeminal neuralgia. Pain. https:\/\/doi.org\/10.1097\/j.pain.0000000000002651","DOI":"10.1097\/j.pain.0000000000002651"},{"key":"2891_CR61","doi-asserted-by":"publisher","unstructured":"Gandini MA, Souza IA, Khullar A, Gambeta E, Zamponi GW (2021) Regulation of CaV3.2 channels by the receptor for activated C kinase 1 (Rack-1). Pflugers Arch. https:\/\/doi.org\/10.1007\/s00424-021-02631-1","DOI":"10.1007\/s00424-021-02631-1"},{"key":"2891_CR62","doi-asserted-by":"publisher","first-page":"92","DOI":"10.3389\/fnbeh.2014.00092","volume":"8","author":"G Gangarossa","year":"2014","unstructured":"Gangarossa G, Laffray S, Bourinet E, Valjent E (2014) T-type calcium channel Cav3.2 deficient mice show elevated anxiety, impaired memory and reduced sensitivity to psychostimulants. Front Behav Neurosci 8:92. https:\/\/doi.org\/10.3389\/fnbeh.2014.00092","journal-title":"Front Behav Neurosci"},{"key":"2891_CR63","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1021\/acschemneuro.1c00765","volume":"13","author":"A Garcia-Caballero","year":"2022","unstructured":"Garcia-Caballero A, Gadotti VM, Ali MY, Bladen C, Gambeta E, Van Humbeck JF, MacCallum JL, Zamponi GW (2022) A synthetically accessible small-molecule inhibitor of USP5-Cav3.2 calcium channel interactions with analgesic properties. ACS Chem Neurosci 13:524\u2013536. https:\/\/doi.org\/10.1021\/acschemneuro.1c00765","journal-title":"ACS Chem Neurosci"},{"key":"2891_CR64","doi-asserted-by":"publisher","first-page":"174480691664244","DOI":"10.1177\/1744806916642444","volume":"12","author":"A Garcia-Caballero","year":"2016","unstructured":"Garcia-Caballero A, Gadotti VM, Chen L, Zamponi GW (2016) A cell-permeant peptide corresponding to the cUBP domain of USP5 reverses inflammatory and neuropathic pain. Mol Pain 12:1744806916642444. https:\/\/doi.org\/10.1177\/1744806916642444","journal-title":"Mol Pain"},{"key":"2891_CR65","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1016\/j.neuron.2014.07.036","volume":"83","author":"A Garc\u00eda-Caballero","year":"2014","unstructured":"Garc\u00eda-Caballero A, Gadotti VM, Stemkowski P, Weiss N, Souza IA, Hodgkinson V, Bladen C, Chen L, Hamid J, Pizzoccaro A, Deage M, Fran\u00e7ois A, Bourinet E, Zamponi GW (2014) The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity. Neuron 83:1144\u20131158. https:\/\/doi.org\/10.1016\/j.neuron.2014.07.036","journal-title":"Neuron"},{"key":"2891_CR66","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s13041-019-0433-8","volume":"12","author":"A Garcia-Caballero","year":"2019","unstructured":"Garcia-Caballero A, Gandini MA, Huang S, Chen L, Souza IA, Dang YL, Stutts MJ, Zamponi GW (2019) Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC. Mol Brain 12:12. https:\/\/doi.org\/10.1186\/s13041-019-0433-8","journal-title":"Mol Brain"},{"key":"2891_CR67","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1186\/s13041-019-0493-9","volume":"12","author":"A Garcia-Caballero","year":"2019","unstructured":"Garcia-Caballero A, Zhang FX, Chen L, M\u2019Dahoma S, Huang J, Zamponi GW (2019) SUMOylation regulates USP5-Cav3.2 calcium channel interactions. Mol Brain 12:73. https:\/\/doi.org\/10.1186\/s13041-019-0493-9","journal-title":"Mol Brain"},{"key":"2891_CR68","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s13041-018-0368-5","volume":"11","author":"A Garcia-Caballero","year":"2018","unstructured":"Garcia-Caballero A, Zhang FX, Hodgkinson V, Huang J, Chen L, Souza IA, Cain S, Kass J, Alles S, Snutch TP, Zamponi GW (2018) T-type calcium channels functionally interact with spectrin (\u03b1\/\u03b2) and ankyrin B. Mol Brain 11:24. https:\/\/doi.org\/10.1186\/s13041-018-0368-5","journal-title":"Mol Brain"},{"key":"2891_CR69","doi-asserted-by":"publisher","first-page":"44","DOI":"10.2174\/1874467211306010006","volume":"6","author":"T Giraldez","year":"2013","unstructured":"Giraldez T, Dom\u00ednguez J, Alvarez de la Rosa D (2013) ENaC in the brain--future perspectives and pharmacological implications. Curr Mol Pharmacol 6:44\u201349. https:\/\/doi.org\/10.2174\/1874467211306010006","journal-title":"Curr Mol Pharmacol"},{"key":"2891_CR70","doi-asserted-by":"publisher","unstructured":"He L, Yu Z, Geng Z, Huang Z, Zhang C, Dong Y, Gao Y, Wang Y, Chen Q, Sun L, Ma X, Huang B, Wang X, Zhao Y (2022) Structure, gating, and pharmacology of human CaV3.3 channel. Nat Commun 13. https:\/\/doi.org\/10.1038\/s41467-022-29728-0","DOI":"10.1038\/s41467-022-29728-0"},{"key":"2891_CR71","doi-asserted-by":"publisher","first-page":"9975","DOI":"10.1523\/JNEUROSCI.2595-06.2006","volume":"26","author":"Y He","year":"2006","unstructured":"He Y, Zu T, Benzow KA, Orr HT, Clark HB, Koob MD (2006) Targeted deletion of a single Sca8 ataxia locus allele in mice causes abnormal gait, progressive loss of motor coordination, and Purkinje cell dendritic deficits. J Neurosci 26:9975\u20139982. https:\/\/doi.org\/10.1523\/JNEUROSCI.2595-06.2006","journal-title":"J Neurosci"},{"key":"2891_CR72","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1002\/ana.21169","volume":"62","author":"SE Heron","year":"2007","unstructured":"Heron SE, Khosravani H, Varela D, Bladen C, Williams TC, Newman MR, Scheffer IE, Berkovic SF, Mulley JC, Zamponi GW (2007) Extended spectrum of idiopathic generalized epilepsies associated with CACNA1H functional variants. Ann Neurol 62:560\u2013568. https:\/\/doi.org\/10.1002\/ana.21169","journal-title":"Ann Neurol"},{"key":"2891_CR73","doi-asserted-by":"publisher","first-page":"1664","DOI":"10.1038\/nn.3859","volume":"17","author":"TS Ho","year":"2014","unstructured":"Ho TS, Zollinger DR, Chang KJ, Xu M, Cooper EC, Stankewich MC, Bennett V, Rasband MN (2014) A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier. Nat Neurosci 17:1664\u20131672. https:\/\/doi.org\/10.1038\/nn.3859","journal-title":"Nat Neurosci"},{"key":"2891_CR74","doi-asserted-by":"publisher","first-page":"7465","DOI":"10.1074\/jbc.M808049200","volume":"284","author":"C Hu","year":"2009","unstructured":"Hu C, Depuy SD, Yao J, McIntire WE, Barrett PQ (2009) Protein kinase A activity controls the regulation of T-type CaV3.2 channels by Gbetagamma dimers. J Biol Chem 284:7465\u20137473. https:\/\/doi.org\/10.1074\/jbc.M808049200","journal-title":"J Biol Chem"},{"key":"2891_CR75","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.coph.2016.10.001","volume":"32","author":"J Huang","year":"2017","unstructured":"Huang J, Zamponi GW (2017) Regulation of voltage gated calcium channels by GPCRs and post-translational modification. Curr Opin Pharmacol 32:1\u20138. https:\/\/doi.org\/10.1016\/j.coph.2016.10.001","journal-title":"Curr Opin Pharmacol"},{"key":"2891_CR76","doi-asserted-by":"publisher","first-page":"2933","DOI":"10.1091\/mbc.11.9.2933","volume":"11","author":"C Hubbard","year":"2000","unstructured":"Hubbard C, Singleton D, Rauch M, Jayasinghe S, Cafiso D, Castle D (2000) The secretory carrier membrane protein family: structure and membrane topology. Mol Biol Cell 11:2933\u20132947. https:\/\/doi.org\/10.1091\/mbc.11.9.2933","journal-title":"Mol Biol Cell"},{"key":"2891_CR77","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1016\/s0896-6273(02)00623-2","volume":"33","author":"SW Hughes","year":"2002","unstructured":"Hughes SW, Cope DW, Blethyn KL, Crunelli V (2002) Cellular mechanisms of the slow (<1 Hz) oscillation in thalamocortical neurons in vitro. Neuron 33:947\u2013958. https:\/\/doi.org\/10.1016\/s0896-6273(02)00623-2","journal-title":"Neuron"},{"key":"2891_CR78","doi-asserted-by":"publisher","first-page":"C1459","DOI":"10.1152\/ajpcell.00322.2006","volume":"292","author":"CK Isacson","year":"2007","unstructured":"Isacson CK, Lu Q, Karas RH, Cox DH (2007) RACK1 is a BKCa channel binding protein. Am J Physiol Cell Physiol 292:C1459\u2013C1466. https:\/\/doi.org\/10.1152\/ajpcell.00322.2006","journal-title":"Am J Physiol Cell Physiol"},{"key":"2891_CR79","doi-asserted-by":"publisher","first-page":"4930","DOI":"10.1523\/JNEUROSCI.20-13-04930.2000","volume":"20","author":"AI Ivanov","year":"2000","unstructured":"Ivanov AI, Calabrese RL (2000) Intracellular Ca2+ dynamics during spontaneous and evoked activity of leech heart interneurons: low-threshold Ca currents and graded synaptic transmission. J Neurosci 20:4930\u20134943. https:\/\/doi.org\/10.1523\/JNEUROSCI.20-13-04930.2000","journal-title":"J Neurosci"},{"key":"2891_CR80","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1002\/jcp.30920","volume":"238","author":"S Jeong","year":"2023","unstructured":"Jeong S, Shim JS, Sin SK, Park K, Lee J (2023) Phosphorylation states greatly regulate the activity and gating properties of Cav3.1 T-type Ca2+ channels. J Cell Physiol 238:210\u2013226. https:\/\/doi.org\/10.1002\/jcp.30920","journal-title":"J Cell Physiol"},{"key":"2891_CR81","doi-asserted-by":"publisher","first-page":"12319","DOI":"10.1074\/jbc.M701019200","volume":"282","author":"S Jiang","year":"2007","unstructured":"Jiang S, Seng S, Avraham HK, Fu Y, Avraham S (2007) Process elongation of oligodendrocytes is promoted by the Kelch-related protein MRP2\/KLHL1. J Biol Chem 282:12319\u201312329. https:\/\/doi.org\/10.1074\/jbc.M701019200","journal-title":"J Biol Chem"},{"key":"2891_CR82","doi-asserted-by":"publisher","first-page":"9681","DOI":"10.1074\/jbc.C400006200","volume":"279","author":"H Khosravani","year":"2004","unstructured":"Khosravani H, Altier C, Simms B, Hamming KS, Snutch TP, Mezeyova J, McRory JE, Zamponi GW (2004) Gating effects of mutations in the Cav3.2 T-type calcium channel associated with childhood absence epilepsy. J Biol Chem 279:9681\u20139684. https:\/\/doi.org\/10.1074\/jbc.C400006200","journal-title":"J Biol Chem"},{"key":"2891_CR83","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1002\/ana.20458","volume":"57","author":"H Khosravani","year":"2005","unstructured":"Khosravani H, Bladen C, Parker DB, Snutch TP, McRory JE, Zamponi GW (2005) Effects of Cav3.2 channel mutations linked to idiopathic generalized epilepsy. Ann Neurol 57:745\u2013749. https:\/\/doi.org\/10.1002\/ana.20458","journal-title":"Ann Neurol"},{"key":"2891_CR84","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1126\/science.1088886","volume":"302","author":"D Kim","year":"2003","unstructured":"Kim D, Park D, Choi S, Lee S, Sun M, Kim C, Shin HS (2003) Thalamic control of visceral nociception mediated by T-type Ca2+ channels. Science 302:117\u2013119. https:\/\/doi.org\/10.1126\/science.1088886","journal-title":"Science"},{"key":"2891_CR85","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/s0896-6273(01)00343-9","volume":"31","author":"D Kim","year":"2001","unstructured":"Kim D, Song I, Keum S, Lee T, Jeong MJ, Kim SS, McEnery MW, Shin HS (2001) Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G) T-type Ca(2+) channels. Neuron 31:35\u201345. https:\/\/doi.org\/10.1016\/s0896-6273(01)00343-9","journal-title":"Neuron"},{"key":"2891_CR86","doi-asserted-by":"publisher","first-page":"5285","DOI":"10.1074\/jbc.M113.523639","volume":"289","author":"CF Kline","year":"2014","unstructured":"Kline CF, Scott J, Curran J, Hund TJ, Mohler PJ (2014) Ankyrin-B regulates Cav2.1 and Cav2.2 channel expression and targeting. J Biol Chem 289:5285\u20135295. https:\/\/doi.org\/10.1074\/jbc.M113.523639","journal-title":"J Biol Chem"},{"key":"2891_CR87","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1083\/jcb.200110003","volume":"156","author":"M Komada","year":"2002","unstructured":"Komada M, Soriano P (2002) [Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier. J Cell Biol 156:337\u2013348. https:\/\/doi.org\/10.1083\/jcb.200110003","journal-title":"J Cell Biol"},{"key":"2891_CR88","doi-asserted-by":"publisher","first-page":"4322","DOI":"10.1111\/febs.15330","volume":"287","author":"G Kozlov","year":"2020","unstructured":"Kozlov G, Gehring K (2020) Calnexin cycle - structural features of the ER chaperone system. FEBS J 287:4322\u20134340. https:\/\/doi.org\/10.1111\/febs.15330","journal-title":"FEBS J"},{"key":"2891_CR89","doi-asserted-by":"publisher","first-page":"393","DOI":"10.4149\/gpb_2016034","volume":"35","author":"L Lacinova","year":"2016","unstructured":"Lacinova L, Weiss N (2016) It takes two T to shape immunity: emerging role for T-type calcium channels in immune cells. Gen Physiol Biophys 35:393\u2013396. https:\/\/doi.org\/10.4149\/gpb_2016034","journal-title":"Gen Physiol Biophys"},{"key":"2891_CR90","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/112_2014_20","volume":"167","author":"J Lazniewska","year":"2014","unstructured":"Lazniewska J, Weiss N (2014) The \u201csweet\u201d side of ion channels. Rev Physiol Biochem Pharmacol 167:67\u2013114. https:\/\/doi.org\/10.1007\/112_2014_20","journal-title":"Rev Physiol Biochem Pharmacol"},{"key":"2891_CR91","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1016\/j.bbamem.2017.01.018","volume":"1859","author":"J Lazniewska","year":"2017","unstructured":"Lazniewska J, Weiss N (2017) Glycosylation of voltage-gated calcium channels in health and disease. Biochim Biophys Acta Biomembr 1859:662\u2013668. https:\/\/doi.org\/10.1016\/j.bbamem.2017.01.018","journal-title":"Biochim Biophys Acta Biomembr"},{"key":"2891_CR92","doi-asserted-by":"publisher","first-page":"1912","DOI":"10.1523\/JNEUROSCI.19-06-01912.1999","volume":"19","author":"JH Lee","year":"1999","unstructured":"Lee JH, Daud AN, Cribbs LL, Lacerda AE, Pereverzev A, Kl\u00f6ckner U, Schneider T, Perez-Reyes E (1999) Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family. J Neurosci 19:1912\u20131921","journal-title":"J Neurosci"},{"key":"2891_CR93","doi-asserted-by":"publisher","first-page":"e2011371118","DOI":"10.1073\/pnas.2011371118","volume":"118","author":"U Lee","year":"2021","unstructured":"Lee U, Choi C, Ryu SH, Park D, Lee SE, Kim K, Kim Y, Chang S (2021) SCAMP5 plays a critical role in axonal trafficking and synaptic localization of NHE6 to adjust quantal size at glutamatergic synapses. Proc Natl Acad Sci USA 118:e2011371118. https:\/\/doi.org\/10.1073\/pnas.2011371118","journal-title":"Proc Natl Acad Sci USA"},{"key":"2891_CR94","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/j.gep.2010.08.003","volume":"10","author":"W Legha","year":"2010","unstructured":"Legha W, Gaillard S, Gascon E, Malapert P, Hocine M, Alonso S, Moqrich A (2010) stac1 and stac2 genes define discrete and distinct subsets of dorsal root ganglia neurons. Gene Expr Patterns 10:368\u2013375. https:\/\/doi.org\/10.1016\/j.gep.2010.08.003","journal-title":"Gene Expr Patterns"},{"key":"2891_CR95","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1016\/s0028-3908(98)00060-4","volume":"37","author":"V Leuranguer","year":"1998","unstructured":"Leuranguer V, Bourinet E, Lory P, Nargeot J (1998) Antisense depletion of beta-subunits fails to affect T-type calcium channels properties in a neuroblastoma cell line. Neuropharmacology 37:701\u2013708. https:\/\/doi.org\/10.1016\/s0028-3908(98)00060-4","journal-title":"Neuropharmacology"},{"key":"2891_CR96","doi-asserted-by":"publisher","first-page":"E1990","DOI":"10.1073\/pnas.1323112111","volume":"111","author":"SS Lin","year":"2014","unstructured":"Lin SS, Tzeng BH, Lee KR, Smith RJ, Campbell KP, Chen CC (2014) Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage. Proc Natl Acad Sci USA 111:E1990\u2013E1998. https:\/\/doi.org\/10.1073\/pnas.1323112111","journal-title":"Proc Natl Acad Sci USA"},{"key":"2891_CR97","doi-asserted-by":"publisher","first-page":"e56629","DOI":"10.7554\/eLife.56629","volume":"9","author":"CH Liu","year":"2020","unstructured":"Liu CH, Seo R, Ho TS, Stankewich M, Mohler PJ, Hund TJ, Noebels JL, Rasband MN (2020) \u03b2 spectrin-dependent and domain specific mechanisms for Na+ channel clustering. Elife 9:e56629. https:\/\/doi.org\/10.7554\/eLife.56629","journal-title":"Elife"},{"key":"2891_CR98","doi-asserted-by":"publisher","first-page":"e52378","DOI":"10.7554\/eLife.52378","volume":"9","author":"CH Liu","year":"2020","unstructured":"Liu CH, Stevens SR, Teliska LH, Stankewich M, Mohler PJ, Hund TJ, Rasband MN (2020) Nodal \u03b2 spectrins are required to maintain Na+ channel clustering and axon integrity. Elife 9:e52378. https:\/\/doi.org\/10.7554\/eLife.52378","journal-title":"Elife"},{"key":"2891_CR99","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/0896-6273(92)90273-g","volume":"8","author":"PM Lledo","year":"1992","unstructured":"Lledo PM, Homburger V, Bockaert J, Vincent JD (1992) Differential G protein-mediated coupling of D2 dopamine receptors to K+ and Ca2+ currents in rat anterior pituitary cells. Neuron 8:455\u2013463. https:\/\/doi.org\/10.1016\/0896-6273(92)90273-g","journal-title":"Neuron"},{"key":"2891_CR100","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1210\/endo-127-3-990","volume":"127","author":"PM Lledo","year":"1990","unstructured":"Lledo PM, Legendre P, Israel JM, Vincent JD (1990) Dopamine inhibits two characterized voltage-dependent calcium currents in identified rat lactotroph cells. Endocrinology 127:990\u20131001. https:\/\/doi.org\/10.1210\/endo-127-3-990","journal-title":"Endocrinology"},{"key":"2891_CR101","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1007\/s00424-020-02429-7","volume":"472","author":"P Lory","year":"2020","unstructured":"Lory P, Nicole S, Monteil A (2020) Neuronal Cav3 channelopathies: recent progress and perspectives. Pflugers Arch 472:831\u2013844. https:\/\/doi.org\/10.1007\/s00424-020-02429-7","journal-title":"Pflugers Arch"},{"key":"2891_CR102","doi-asserted-by":"publisher","first-page":"F183","DOI":"10.1152\/ajprenal.1994.267.1.F183","volume":"267","author":"HK Lu","year":"1994","unstructured":"Lu HK, Fern RJ, Nee JJ, Barrett PQ (1994) Ca(2+)-dependent activation of T-type Ca2+ channels by calmodulin-dependent protein kinase II. Am J Physiol 267:F183\u2013F189. https:\/\/doi.org\/10.1152\/ajprenal.1994.267.1.F183","journal-title":"Am J Physiol"},{"key":"2891_CR103","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.neuroscience.2019.04.024","volume":"409","author":"A Lundt","year":"2019","unstructured":"Lundt A, Seidel R, So\u00f3s J, Henseler C, M\u00fcller R, Bakki M, Arshaad MI, Ehninger D, Hescheler J, Sachinidis A, Broich K, Wormuth C, Papazoglou A, Weiergr\u00e4ber M (2019) Cav3.2 T-type calcium channels are physiologically mandatory for the auditory system. Neuroscience 409:81\u2013100. https:\/\/doi.org\/10.1016\/j.neuroscience.2019.04.024","journal-title":"Neuroscience"},{"key":"2891_CR104","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.bbamem.2013.05.002","volume":"1838","author":"B Machnicka","year":"2014","unstructured":"Machnicka B, Czogalla A, Hryniewicz-Jankowska A, Bogus\u0142awska DM, Grochowalska R, Heger E, Sikorski AF (2014) Spectrins: a structural platform for stabilization and activation of membrane channels, receptors and transporters. Biochim Biophys Acta 1838:620\u2013634. https:\/\/doi.org\/10.1016\/j.bbamem.2013.05.002","journal-title":"Biochim Biophys Acta"},{"key":"2891_CR105","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.ceca.2012.01.005","volume":"51","author":"S Mahapatra","year":"2012","unstructured":"Mahapatra S, Calorio C, Vandael DH, Marcantoni A, Carabelli V, Carbone E (2012) Calcium channel types contributing to chromaffin cell excitability, exocytosis and endocytosis. Cell Calcium 51:321\u2013330. https:\/\/doi.org\/10.1016\/j.ceca.2012.01.005","journal-title":"Cell Calcium"},{"key":"2891_CR106","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.1161\/01.RES.0000225862.14314.49","volume":"98","author":"ME Mangoni","year":"2006","unstructured":"Mangoni ME, Traboulsie A, Leoni AL, Couette B, Marger L, Le Quang K, Kupfer E, Cohen-Solal A, Vilar J, Shin HS, Escande D, Charpentier F, Nargeot J, Lory P (2006) Bradycardia and slowing of the atrioventricular conduction in mice lacking CaV3.1\/alpha1G T-type calcium channels. Circ Res 98:1422\u20131430. https:\/\/doi.org\/10.1161\/01.RES.0000225862.14314.49","journal-title":"Circ Res"},{"key":"2891_CR107","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1007\/BF00586670","volume":"406","author":"C Marchetti","year":"1986","unstructured":"Marchetti C, Carbone E, Lux HD (1986) Effects of dopamine and noradrenaline on Ca channels of cultured sensory and sympathetic neurons of chick. Pflugers Arch 406:104\u2013111. https:\/\/doi.org\/10.1007\/BF00586670","journal-title":"Pflugers Arch"},{"key":"2891_CR108","doi-asserted-by":"publisher","first-page":"2433","DOI":"10.1074\/jbc.M110.182550","volume":"286","author":"YS Markandeya","year":"2011","unstructured":"Markandeya YS, Fahey JM, Pluteanu F, Cribbs LL, Balijepalli RC (2011) Caveolin-3 regulates protein kinase A modulation of the Ca(V)3.2 (alpha1H) T-type Ca2+ channels. J Biol Chem 286:2433\u20132444. https:\/\/doi.org\/10.1074\/jbc.M110.182550","journal-title":"J Biol Chem"},{"key":"2891_CR109","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1007\/s00424-014-1482-6","volume":"466","author":"P Mesirca","year":"2014","unstructured":"Mesirca P, Torrente AG, Mangoni ME (2014) T-type channels in the sino-atrial and atrioventricular pacemaker mechanism. Pflugers Arch 466:791\u2013799. https:\/\/doi.org\/10.1007\/s00424-014-1482-6","journal-title":"Pflugers Arch"},{"key":"2891_CR110","doi-asserted-by":"publisher","first-page":"4501","DOI":"10.1523\/jneurosci.2844-07.2008","volume":"28","author":"A Mezghrani","year":"2008","unstructured":"Mezghrani A, Monteil A, Watschinger K, Sinnegger-Brauns MJ, Barr\u00e8re C, Bourinet E, Nargeot J, Striessnig J, Lory P (2008) A destructive interaction mechanism accounts for dominant-negative effects of misfolded mutants of voltage-gated calcium channels. J Neurosci 28:4501\u20134511. https:\/\/doi.org\/10.1523\/jneurosci.2844-07.2008","journal-title":"J Neurosci"},{"key":"2891_CR111","doi-asserted-by":"publisher","first-page":"16168","DOI":"10.1074\/jbc.m114.634261","volume":"290","author":"A Monteil","year":"2015","unstructured":"Monteil A, Chausson P, Boutourlinsky K, Mezghrani A, Huc-Brandt S, Blesneac I, Bidaud I, Lemmers C, Leresche N, Lambert RC, Lory P (2015) Inhibition of Cav3.2 T-type calcium channels by its intracellular I-II loop. J Biol Chem 290:16168\u201316176. https:\/\/doi.org\/10.1074\/jbc.m114.634261","journal-title":"J Biol Chem"},{"key":"2891_CR112","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1186\/s13041-015-0180-4","volume":"8","author":"H Morino","year":"2015","unstructured":"Morino H, Matsuda Y, Muguruma K, Miyamoto R, Ohsawa R, Ohtake T, Otobe R, Watanabe M, Maruyama H, Hashimoto K, Kawakami H (2015) A mutation in the low voltage-gated calcium channel CACNA1G alters the physiological properties of the channel, causing spinocerebellar ataxia. Mol Brain 8:89. https:\/\/doi.org\/10.1186\/s13041-015-0180-4","journal-title":"Mol Brain"},{"key":"2891_CR113","doi-asserted-by":"publisher","first-page":"14950","DOI":"10.1073\/pnas.1005940107","volume":"107","author":"CS M\u00fcller","year":"2010","unstructured":"M\u00fcller CS, Haupt A, Bildl W, Schindler J, Knaus H-G, Meissner M, Rammner B, Striessnig J, Flockerzi V, Fakler B, Schulte U (2010) Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain. Proc Natl Acad Sci 107:14950\u201314957. https:\/\/doi.org\/10.1073\/pnas.1005940107","journal-title":"Proc Natl Acad Sci"},{"key":"2891_CR114","doi-asserted-by":"publisher","first-page":"28901","DOI":"10.1074\/jbc.M602848200","volume":"281","author":"HK M\u00fcller","year":"2006","unstructured":"M\u00fcller HK, Wiborg O, Haase J (2006) Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2. J Biol Chem 281:28901\u201328909. https:\/\/doi.org\/10.1074\/jbc.M602848200","journal-title":"J Biol Chem"},{"key":"2891_CR115","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/s13041-022-00978-9","volume":"15","author":"ER Mustaf\u00e1","year":"2022","unstructured":"Mustaf\u00e1 ER, Gambeta E, Stringer RN, Souza IA, Zamponi GW, Weiss N (2022) Electrophysiological and computational analysis of Cav3.2 channel variants associated with familial trigeminal neuralgia. Mol. Brain 15:91. https:\/\/doi.org\/10.1186\/s13041-022-00978-9","journal-title":"Brain"},{"key":"2891_CR116","doi-asserted-by":"publisher","first-page":"2230776","DOI":"10.1080\/19336950.2023.2230776","volume":"17","author":"ER Mustaf\u00e1","year":"2023","unstructured":"Mustaf\u00e1 ER, Wei\u00df K, Weiss N (2023) Secretory carrier-associated membrane protein 5 regulates cell-surface targeting of T-type calcium channels. Channels (Austin) 17:2230776. https:\/\/doi.org\/10.1080\/19336950.2023.2230776","journal-title":"Channels (Austin)"},{"key":"2891_CR117","doi-asserted-by":"publisher","first-page":"11881","DOI":"10.1073\/pnas.1310571110","volume":"110","author":"BR Nelson","year":"2013","unstructured":"Nelson BR, Wu F, Liu Y, Anderson DM, McAnally J, Lin W, Cannon SC, Bassel-Duby R, Olson EN (2013) Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility. Proc Natl Acad Sci USA 110:11881\u201311886. https:\/\/doi.org\/10.1073\/pnas.1310571110","journal-title":"Proc Natl Acad Sci USA"},{"key":"2891_CR118","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1093\/hmg\/9.10.1543","volume":"9","author":"JP Nemes","year":"2000","unstructured":"Nemes JP, Benzow KA, Moseley ML, Ranum LP, Koob MD (2000) The SCA8 transcript is an antisense RNA to a brain-specific transcript encoding a novel actin-binding protein (KLHL1). Hum Mol Genet 9:1543\u20131551. https:\/\/doi.org\/10.1093\/hmg\/9.10.1543","journal-title":"Hum Mol Genet"},{"key":"2891_CR119","doi-asserted-by":"publisher","first-page":"3828","DOI":"10.2337\/db13-0813","volume":"62","author":"P Orestes","year":"2013","unstructured":"Orestes P, Osuru HP, McIntire WE, Jacus MO, Salajegheh R, Jagodic MM, Choe W, Lee J, Lee SS, Rose KE, Poiro N, Digruccio MR, Krishnan K, Covey DF, Lee JH, Barrett PQ, Jevtovic-Todorovic V, Todorovic SM (2013) Reversal of neuropathic pain in diabetes by targeting glycosylation of Ca(V)3.2 T-type calcium channels. Diabetes 62:3828\u20133838. https:\/\/doi.org\/10.2337\/db13-0813","journal-title":"Diabetes"},{"key":"2891_CR120","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/s0896-6273(01)00454-8","volume":"32","author":"ZH Pan","year":"2001","unstructured":"Pan ZH, Hu HJ, Perring P, Andrade R (2001) T-type Ca(2+) channels mediate neurotransmitter release in retinal bipolar cells. Neuron 32:89\u201398. https:\/\/doi.org\/10.1016\/s0896-6273(01)00454-8","journal-title":"Neuron"},{"key":"2891_CR121","doi-asserted-by":"publisher","first-page":"2328","DOI":"10.1073\/pnas.0308567100","volume":"101","author":"RL Patterson","year":"2004","unstructured":"Patterson RL, van Rossum DB, Barrow RK, Snyder SH (2004) RACK1 binds to inositol 1,4,5-trisphosphate receptors and mediates Ca2+ release. Proc Natl Acad Sci USA 101:2328\u20132332. https:\/\/doi.org\/10.1073\/pnas.0308567100","journal-title":"Proc Natl Acad Sci USA"},{"key":"2891_CR122","doi-asserted-by":"publisher","first-page":"875","DOI":"10.5665\/sleep.5646","volume":"39","author":"C Pellegrini","year":"2016","unstructured":"Pellegrini C, Lecci S, L\u00fcthi A, Astori S (2016) Suppression of sleep spindle rhythmogenesis in mice with deletion of CaV3.2 and CaV3.3 T-type Ca(2+) channels. Sleep 39:875\u2013885. https:\/\/doi.org\/10.5665\/sleep.5646","journal-title":"Sleep"},{"key":"2891_CR123","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1111\/j.1528-1167.2006.00482.x","volume":"47","author":"JB Peloquin","year":"2006","unstructured":"Peloquin JB, Khosravani H, Barr W, Bladen C, Evans R, Mezeyova J, Parker D, Snutch TP, McRory JE, Zamponi GW (2006) Functional analysis of Ca3.2 T-type calcium channel mutations linked to childhood absence epilepsy. Epilepsia 47:655\u2013658. https:\/\/doi.org\/10.1111\/j.1528-1167.2006.00482.x","journal-title":"Epilepsia"},{"key":"2891_CR124","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1038\/36110","volume":"391","author":"E Perez-Reyes","year":"1998","unstructured":"Perez-Reyes E, Cribbs LL, Daud A, Lacerda AE, Barclay J, Williamson MP, Fox M, Rees M, Lee JH (1998) Molecular characterization of a neuronal low-voltage-activated T-type calcium channel. Nature 391:896\u2013900. https:\/\/doi.org\/10.1038\/36110","journal-title":"Nature"},{"key":"2891_CR125","doi-asserted-by":"publisher","first-page":"444","DOI":"10.3389\/fncel.2014.00444","volume":"8","author":"PP Perissinotti","year":"2014","unstructured":"Perissinotti PP, Ethington EA, Almazan E, Mart\u00ednez-Hern\u00e1ndez E, Kalil J, Koob MD, Piedras-Renter\u00eda ES (2014) Calcium current homeostasis and synaptic deficits in hippocampal neurons from Kelch-like 1 knockout mice. Front Cell Neurosci 8:444. https:\/\/doi.org\/10.3389\/fncel.2014.00444","journal-title":"Front Cell Neurosci"},{"key":"2891_CR126","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.ceca.2014.03.002","volume":"55","author":"PP Perissinotti","year":"2014","unstructured":"Perissinotti PP, Ethington EG, Cribbs L, Koob MD, Martin J, Piedras-Renter\u00eda ES (2014) Down-regulation of endogenous KLHL1 decreases voltage-gated calcium current density. Cell Calcium 55:269\u2013280. https:\/\/doi.org\/10.1016\/j.ceca.2014.03.002","journal-title":"Cell Calcium"},{"key":"2891_CR127","doi-asserted-by":"publisher","first-page":"9215","DOI":"10.1523\/JNEUROSCI.0695-18.2018","volume":"38","author":"A Polster","year":"2018","unstructured":"Polster A, Dittmer PJ, Perni S, Bichraoui H, Sather WA, Beam KG (2018) Stac proteins suppress Ca2+-dependent inactivation of neuronal l-type Ca2+ channels. J Neurosci 38:9215\u20139227. https:\/\/doi.org\/10.1523\/JNEUROSCI.0695-18.2018","journal-title":"J Neurosci"},{"key":"2891_CR128","doi-asserted-by":"publisher","first-page":"11513","DOI":"10.1038\/s41598-017-11591-5","volume":"7","author":"J Proft","year":"2017","unstructured":"Proft J, Rzhepetskyy Y, Lazniewska J, Zhang FX, Cain SM, Snutch TP, Zamponi GW, Weiss N (2017) The Cacna1h mutation in the GAERS model of absence epilepsy enhances T-type Ca2+ currents by altering calnexin-dependent trafficking of Cav3.2 channels. Sci Rep 7:11513. https:\/\/doi.org\/10.1038\/s41598-017-11591-5","journal-title":"Sci Rep"},{"key":"2891_CR129","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1124\/mol.114.096008","volume":"87","author":"J Proft","year":"2015","unstructured":"Proft J, Weiss N (2015) G protein regulation of neuronal calcium channels: back to the future. Mol Pharmacol 87:890\u2013906. https:\/\/doi.org\/10.1124\/mol.114.096008","journal-title":"Mol Pharmacol"},{"key":"2891_CR130","doi-asserted-by":"publisher","first-page":"e61844","DOI":"10.1371\/journal.pone.0061844","volume":"8","author":"R Rehak","year":"2013","unstructured":"Rehak R, Bartoletti TM, Engbers JD, Berecki G, Turner RW, Zamponi GW (2013) Low voltage activation of KCa1.1 current by Cav3-KCa1.1 complexes. PLoS One 8:e61844. https:\/\/doi.org\/10.1371\/journal.pone.0061844","journal-title":"PLoS One"},{"key":"2891_CR131","doi-asserted-by":"publisher","first-page":"100874","DOI":"10.1016\/j.jbc.2021.100874","volume":"297","author":"B Rufenach","year":"2021","unstructured":"Rufenach B, Van Petegem F (2021) Structure and function of STAC proteins: calcium channel modulators and critical components of muscle excitation-contraction coupling. J Biol Chem 297:100874. https:\/\/doi.org\/10.1016\/j.jbc.2021.100874","journal-title":"J Biol Chem"},{"key":"2891_CR132","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1080\/19336950.2016.1204497","volume":"10","author":"Y Rzhepetskyy","year":"2016","unstructured":"Rzhepetskyy Y, Lazniewska J, Blesneac I, Pamphlett R, Weiss N (2016) CACNA1H missense mutations associated with amyotrophic lateral sclerosis alter Cav3.2 T-type calcium channel activity and reticular thalamic neuron firing. Channels (Austin) 10:466\u2013477. https:\/\/doi.org\/10.1080\/19336950.2016.1204497","journal-title":"Channels (Austin)"},{"key":"2891_CR133","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1080\/19336950.2016.1186318","volume":"10","author":"Y Rzhepetskyy","year":"2016","unstructured":"Rzhepetskyy Y, Lazniewska J, Proft J, Campiglio M, Flucher BE, Weiss N (2016) A Cav3.2\/Stac1 molecular complex controls T-type channel expression at the plasma membrane. Channels (Austin) 10:346\u2013354. https:\/\/doi.org\/10.1080\/19336950.2016.1186318","journal-title":"Channels (Austin)"},{"key":"2891_CR134","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.neuropharm.2015.09.032","volume":"101","author":"S Sakkaki","year":"2016","unstructured":"Sakkaki S, Gangarossa G, Lerat B, Fran\u00e7on D, Forichon L, Chemin J, Valjent E, Lerner-Natoli M, Lory P (2016) Blockade of T-type calcium channels prevents tonic-clonic seizures in a maximal electroshock seizure model. Neuropharmacology 101:320\u2013329. https:\/\/doi.org\/10.1016\/j.neuropharm.2015.09.032","journal-title":"Neuropharmacology"},{"key":"2891_CR135","doi-asserted-by":"publisher","first-page":"e06315","DOI":"10.7554\/eLife.06315","volume":"4","author":"UI Scholl","year":"2015","unstructured":"Scholl UI, St\u00f6lting G, Nelson-Williams C, Vichot AA, Choi M, Loring E, Prasad ML, Goh G, Carling T, Juhlin CC, Quack I, Rump LC, Thiel A, Lande M, Frazier BG, Rasoulpour M, Bowlin DL, Sethna CB, Trachtman H et al (2015) Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism. Elife 4:e06315. https:\/\/doi.org\/10.7554\/eLife.06315","journal-title":"Elife"},{"key":"2891_CR136","doi-asserted-by":"publisher","first-page":"104404","DOI":"10.1016\/j.phrs.2019.104404","volume":"148","author":"X Shi","year":"2019","unstructured":"Shi X, Xiang S, Cao J, Zhu H, Yang B, He Q, Ying M (2019) Kelch-like proteins: Physiological functions and relationships with diseases. Pharmacol Res 148:104404. https:\/\/doi.org\/10.1016\/j.phrs.2019.104404","journal-title":"Pharmacol Res"},{"key":"2891_CR137","doi-asserted-by":"publisher","first-page":"2031","DOI":"10.1152\/jn.00821.2001","volume":"87","author":"MR Smith","year":"2002","unstructured":"Smith MR, Nelson AB, Du Lac S (2002) Regulation of firing response gain by calcium-dependent mechanisms in vestibular nucleus neurons. J Neurophysiol 87:2031\u20132042. https:\/\/doi.org\/10.1152\/jn.00821.2001","journal-title":"J Neurophysiol"},{"key":"2891_CR138","doi-asserted-by":"publisher","first-page":"22085","DOI":"10.1074\/jbc.M603316200","volume":"281","author":"I Splawski","year":"2006","unstructured":"Splawski I, Yoo DS, Stotz SC, Cherry A, Clapham DE, Keating MT (2006) CACNA1H mutations in autism spectrum disorders. J Biol Chem 281:22085\u201322091. https:\/\/doi.org\/10.1074\/jbc.M603316200","journal-title":"J Biol Chem"},{"key":"2891_CR139","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1080\/19336950.2019.1600968","volume":"13","author":"GJ Stephens","year":"2019","unstructured":"Stephens GJ, Cottrell GS (2019) CACHD1: A new activity-modifying protein for voltage-gated calcium channels. Channels (Austin) 13:120\u2013123. https:\/\/doi.org\/10.1080\/19336950.2019.1600968","journal-title":"Channels (Austin)"},{"key":"2891_CR140","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1186\/s12864-019-5512-9","volume":"20","author":"KE Stephens","year":"2019","unstructured":"Stephens KE, Zhou W, Ji Z, Chen Z, He S, Ji H, Guan Y, Taverna SD (2019) Sex differences in gene regulation in the dorsal root ganglion after nerve injury. BMC Genomics 20:147. https:\/\/doi.org\/10.1186\/s12864-019-5512-9","journal-title":"BMC Genomics"},{"key":"2891_CR141","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1080\/19336950.2022.2120467","volume":"16","author":"SR Stevens","year":"2022","unstructured":"Stevens SR, Rasband MN (2022) Pleiotropic ankyrins: scaffolds for ion channels and transporters. Channels (Austin) 16:216\u2013229. https:\/\/doi.org\/10.1080\/19336950.2022.2120467","journal-title":"Channels (Austin)"},{"key":"2891_CR142","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/s13041-023-01058-2","volume":"16","author":"RN Stringer","year":"2023","unstructured":"Stringer RN, Cmarko L, Zamponi GW, De Waard M, Weiss N (2023) Electrophysiological characterization of a Cav3.2 calcium channel missense variant associated with epilepsy and hearing loss. Mol. Brain 16:68. https:\/\/doi.org\/10.1186\/s13041-023-01058-2","journal-title":"Brain"},{"key":"2891_CR143","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/s13041-020-00577-6","volume":"13","author":"RN Stringer","year":"2020","unstructured":"Stringer RN, Jurkovicova-Tarabova B, Huang S, Haji-Ghassemi O, Idoux R, Liashenko A, Souza IA, Rzhepetskyy Y, Lacinova L, Van Petegem F, Zamponi GW, Pamphlett R, Weiss N (2020) A rare CACNA1H variant associated with amyotrophic lateral sclerosis causes complete loss of Cav3.2\u2009T-type channel activity. Mol. Brain 13:33. https:\/\/doi.org\/10.1186\/s13041-020-00577-6","journal-title":"Brain"},{"key":"2891_CR144","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1186\/s13041-021-00838-y","volume":"14","author":"RN Stringer","year":"2021","unstructured":"Stringer RN, Jurkovicova-Tarabova B, Souza IA, Ibrahim J, Vacik T, Fathalla WM, Hertecant J, Zamponi GW, Lacinova L, Weiss N (2021) De novo SCN8A and inherited rare CACNA1H variants associated with severe developmental and epileptic encephalopathy. Mol Brain 14:126. https:\/\/doi.org\/10.1186\/s13041-021-00838-y","journal-title":"Mol Brain"},{"key":"2891_CR145","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1080\/19336950.2020.1745406","volume":"14","author":"RN Stringer","year":"2020","unstructured":"Stringer RN, Lazniewska J, Weiss N (2020) Transcriptomic analysis of glycan-processing genes in the dorsal root ganglia of diabetic mice and functional characterization on Cav3.2 channels. Channels (Austin) 14:132\u2013140. https:\/\/doi.org\/10.1080\/19336950.2020.1745406","journal-title":"Channels (Austin)"},{"key":"2891_CR146","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1006\/bbrc.1996.1900","volume":"229","author":"H Suzuki","year":"1996","unstructured":"Suzuki H, Kawai J, Taga C, Yaoi T, Hara A, Hirose K, Hayashizaki Y, Watanabe S (1996) Stac, a novel neuron-specific protein with cysteine-rich and SH3 domains. Biochem Biophys Res Commun 229:902\u2013909. https:\/\/doi.org\/10.1006\/bbrc.1996.1900","journal-title":"Biochem Biophys Res Commun"},{"key":"2891_CR147","doi-asserted-by":"publisher","first-page":"1895","DOI":"10.1523\/JNEUROSCI.19-06-01895.1999","volume":"19","author":"EM Talley","year":"1999","unstructured":"Talley EM, Cribbs LL, Lee JH, Daud A, Perez-Reyes E, Bayliss DA (1999) Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels. J Neurosci 19:1895\u20131911","journal-title":"J Neurosci"},{"key":"2891_CR148","doi-asserted-by":"publisher","unstructured":"Tamang HK, Yang RB, Song ZH, Hsu SC, Peng CC, Tung YC, Tzeng BH, Chen CC (2022) Cav 3.2 T-type calcium channel regulates mouse platelet activation and arterial thrombosis. J Thromb Haemost. https:\/\/doi.org\/10.1111\/jth.15745","DOI":"10.1111\/jth.15745"},{"key":"2891_CR149","doi-asserted-by":"publisher","first-page":"2125","DOI":"10.1002\/jbmr.437","volume":"26","author":"WR Thompson","year":"2011","unstructured":"Thompson WR, Majid AS, Czymmek KJ, Ruff AL, Garc\u00eda J, Duncan RL, Farach-Carson MC (2011) Association of the \u03b12\u03b41 subunit with Cav3.2 enhances membrane expression and regulates mechanically induced ATP release in MLO-Y4 osteocytes. J Bone Min Res 26:2125\u20132139. https:\/\/doi.org\/10.1002\/jbmr.437","journal-title":"J Bone Min Res"},{"key":"2891_CR150","doi-asserted-by":"publisher","first-page":"3110","DOI":"10.1523\/JNEUROSCI.15-04-03110.1995","volume":"15","author":"E Tsakiridou","year":"1995","unstructured":"Tsakiridou E, Bertollini L, de Curtis M, Avanzini G, Pape HC (1995) Selective increase in T-type calcium conductance of reticular thalamic neurons in a rat model of absence epilepsy. J Neurosci 15:3110\u20133117","journal-title":"J Neurosci"},{"key":"2891_CR151","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1007\/s00424-013-1434-6","volume":"466","author":"RW Turner","year":"2014","unstructured":"Turner RW, Zamponi GW (2014) T-type channels buddy up. Pflugers Arch 466:661\u2013675. https:\/\/doi.org\/10.1007\/s00424-013-1434-6","journal-title":"Pflugers Arch"},{"key":"2891_CR152","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.1172\/JCI36954","volume":"119","author":"VN Uebele","year":"2009","unstructured":"Uebele VN, Gotter AL, Nuss CE, Kraus RL, Doran SM, Garson SL, Reiss DR, Li Y, Barrow JC, Reger TS, Yang ZQ, Ballard JE, Tang C, Metzger JM, Wang SP, Koblan KS, Renger JJ (2009) Antagonism of T-type calcium channels inhibits high-fat diet-induced weight gain in mice. J Clin Invest 119:1659\u20131667. https:\/\/doi.org\/10.1172\/JCI36954","journal-title":"J Clin Invest"},{"key":"2891_CR153","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1523\/JNEUROSCI.1817-06.2007","volume":"27","author":"I Vitko","year":"2007","unstructured":"Vitko I, Bidaud I, Arias JM, Mezghrani A, Lory P, Perez-Reyes E (2007) The I-II loop controls plasma membrane expression and gating of Ca(v)3.2 T-type Ca2+ channels: a paradigm for childhood absence epilepsy mutations. J Neurosci 27:322\u2013330. https:\/\/doi.org\/10.1523\/JNEUROSCI.1817-06.2007","journal-title":"J Neurosci"},{"key":"2891_CR154","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1016\/j.immuni.2016.01.015","volume":"44","author":"H Wang","year":"2016","unstructured":"Wang H, Zhang X, Xue L, Xing J, Jouvin MH, Putney JW, Anderson MP, Trebak M, Kinet JP (2016) Low-Voltage-Activated CaV3.1 Calcium channels shape T helper cell cytokine profiles. Immunity 44:782\u2013794. https:\/\/doi.org\/10.1016\/j.immuni.2016.01.015","journal-title":"Immunity"},{"key":"2891_CR155","doi-asserted-by":"publisher","first-page":"1778","DOI":"10.1111\/jth.15764","volume":"20","author":"N Weiss","year":"2022","unstructured":"Weiss N (2022) T-type channels: a new route for calcium entry into platelets. J Thromb Haemost 20:1778\u20131780. https:\/\/doi.org\/10.1111\/jth.15764","journal-title":"J Thromb Haemost"},{"key":"2891_CR156","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1007\/s00424-013-1259-3","volume":"465","author":"N Weiss","year":"2013","unstructured":"Weiss N, Black SA, Bladen C, Chen L, Zamponi GW (2013) Surface expression and function of Cav3.2 T-type calcium channels are controlled by asparagine-linked glycosylation. Pflugers Arch 465:1159\u20131170. https:\/\/doi.org\/10.1007\/s00424-013-1259-3","journal-title":"Pflugers Arch"},{"key":"2891_CR157","doi-asserted-by":"publisher","first-page":"2810","DOI":"10.1074\/jbc.M111.290882","volume":"287","author":"N Weiss","year":"2012","unstructured":"Weiss N, Hameed S, Fern\u00e1ndez-Fern\u00e1ndez JM, Fablet K, Karmazinova M, Poillot C, Proft J, Chen L, Bidaud I, Monteil A, Huc-Brandt S, Lacinova L, Lory P, Zamponi GW, De Waard M (2012) A Ca(v)3.2\/syntaxin-1A signaling complex controls T-type channel activity and low-threshold exocytosis. J Biol Chem 287:2810\u20132818. https:\/\/doi.org\/10.1074\/jbc.M111.290882","journal-title":"J Biol Chem"},{"key":"2891_CR158","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1007\/978-94-007-2888-2_33","volume":"740","author":"N Weiss","year":"2012","unstructured":"Weiss N, Zamponi GW (2012) Regulation of voltage-gated calcium channels by synaptic proteins. Adv Exp Med Biol 740:759\u2013775. https:\/\/doi.org\/10.1007\/978-94-007-2888-2_33","journal-title":"Adv Exp Med Biol"},{"key":"2891_CR159","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.1016\/j.bbamem.2012.07.031","volume":"1828","author":"N Weiss","year":"2013","unstructured":"Weiss N, Zamponi GW (2013) Control of low-threshold exocytosis by T-type calcium channels. Biochim Biophys Acta 1828:1579\u20131586. https:\/\/doi.org\/10.1016\/j.bbamem.2012.07.031","journal-title":"Biochim Biophys Acta"},{"key":"2891_CR160","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1136\/jmedgenet-2019-106163","volume":"57","author":"N Weiss","year":"2020","unstructured":"Weiss N, Zamponi GW (2020) Genetic T-type calcium channelopathies. J Med Genet 57:1\u201310. https:\/\/doi.org\/10.1136\/jmedgenet-2019-106163","journal-title":"J Med Genet"},{"key":"2891_CR161","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1007\/s10571-020-00894-3","volume":"41","author":"N Weiss","year":"2021","unstructured":"Weiss N, Zamponi GW (2021) Opioid receptor regulation of neuronal voltage-gated calcium channels. Cell Mol Neurobiol 41:839\u2013847. https:\/\/doi.org\/10.1007\/s10571-020-00894-3","journal-title":"Cell Mol Neurobiol"},{"key":"2891_CR162","doi-asserted-by":"publisher","first-page":"10116","DOI":"10.1523\/JNEUROSCI.23-31-10116.2003","volume":"23","author":"PJ Welsby","year":"2003","unstructured":"Welsby PJ, Wang H, Wolfe JT, Colbran RJ, Johnson ML, Barrett PQ (2003) A mechanism for the direct regulation of T-type calcium channels by Ca2+\/calmodulin-dependent kinase II. J Neurosci 23:10116\u201310121","journal-title":"J Neurosci"},{"key":"2891_CR163","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1523\/JNEUROSCI.10-03-00757.1990","volume":"10","author":"PJ Williams","year":"1990","unstructured":"Williams PJ, MacVicar BA, Pittman QJ (1990) Synaptic modulation by dopamine of calcium currents in rat pars intermedia. J Neurosci 10:757\u2013763. https:\/\/doi.org\/10.1523\/JNEUROSCI.10-03-00757.1990","journal-title":"J Neurosci"},{"key":"2891_CR164","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1111\/j.1469-7793.1997.689ba.x","volume":"505","author":"SR Williams","year":"1997","unstructured":"Williams SR, T\u00f3th TI, Turner JP, Hughes SW, Crunelli V (1997) The \u2018window\u2019 component of the low threshold Ca2+ current produces input signal amplification and bistability in cat and rat thalamocortical neurones. J Physiol 505:689\u2013705. https:\/\/doi.org\/10.1111\/j.1469-7793.1997.689ba.x","journal-title":"J Physiol"},{"key":"2891_CR165","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1186\/gb-2004-5-3-214","volume":"5","author":"TM Williams","year":"2004","unstructured":"Williams TM, Lisanti MP (2004) The caveolin proteins. Genome Biol 5:214. https:\/\/doi.org\/10.1186\/gb-2004-5-3-214","journal-title":"Genome Biol"},{"key":"2891_CR166","doi-asserted-by":"publisher","first-page":"3404","DOI":"10.1523\/JNEUROSCI.22-09-03404.2002","volume":"22","author":"J Wolfart","year":"2002","unstructured":"Wolfart J, Roeper J (2002) Selective coupling of T-type calcium channels to SK potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons. J Neurosci 22:3404\u20133413. https:\/\/doi.org\/10.1523\/JNEUROSCI.22-09-03404.2002","journal-title":"J Neurosci"},{"key":"2891_CR167","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1038\/nature01772","volume":"424","author":"JT Wolfe","year":"2003","unstructured":"Wolfe JT, Wang H, Howard J, Garrison JC, Barrett PQ (2003) T-type calcium channel regulation by specific G-protein betagamma subunits. Nature 424:209\u2013213. https:\/\/doi.org\/10.1038\/nature01772","journal-title":"Nature"},{"key":"2891_CR168","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1113\/jphysiol.2001.012839","volume":"538","author":"JT Wolfe","year":"2002","unstructured":"Wolfe JT, Wang H, Perez-Reyes E, Barrett PQ (2002) Stimulation of recombinant Ca(v)3.2, T-type, Ca(2+) channel currents by CaMKIIgamma(C). J Physiol 538:343\u2013355. https:\/\/doi.org\/10.1113\/jphysiol.2001.012839","journal-title":"J Physiol"},{"key":"2891_CR169","doi-asserted-by":"publisher","first-page":"8045","DOI":"10.1074\/jbc.M109.033605","volume":"285","author":"GE Woodard","year":"2010","unstructured":"Woodard GE, L\u00f3pez JJ, Jard\u00edn I, Salido GM, Rosado JA (2010) TRPC3 regulates agonist-stimulated Ca2+ mobilization by mediating the interaction between type I inositol 1,4,5-trisphosphate receptor, RACK1, and Orai1. J Biol Chem 285:8045\u20138053. https:\/\/doi.org\/10.1074\/jbc.M109.033605","journal-title":"J Biol Chem"},{"key":"2891_CR170","doi-asserted-by":"publisher","first-page":"6551","DOI":"10.1074\/jbc.M111.305854","volume":"287","author":"J Yang","year":"2012","unstructured":"Yang J, Wang Q, Zheng W, Tuli J, Li Q, Wu Y, Hussein S, Dai XQ, Shafiei S, Li XG, Shen PY, Tu JC, Chen XZ (2012) Receptor for activated C kinase 1 (RACK1) inhibits function of transient receptor potential (TRP)-type channel Pkd2L1 through physical interaction. J Biol Chem 287:6551\u20136561. https:\/\/doi.org\/10.1074\/jbc.M111.305854","journal-title":"J Biol Chem"},{"key":"2891_CR171","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1530\/JOE-19-0259","volume":"244","author":"T Yang","year":"2020","unstructured":"Yang T, He M, Zhang H, Barrett PQ, Hu C (2020) L- and T-type calcium channels control aldosterone production from human adrenals. J Endocrinol 244:237\u2013247. https:\/\/doi.org\/10.1530\/JOE-19-0259","journal-title":"J Endocrinol"},{"key":"2891_CR172","doi-asserted-by":"publisher","first-page":"2403","DOI":"10.1172\/JCI27918","volume":"116","author":"J Yao","year":"2006","unstructured":"Yao J, Davies LA, Howard JD, Adney SK, Welsby PJ, Howell N, Carey RM, Colbran RJ, Barrett PQ (2006) Molecular basis for the modulation of native T-type Ca2+ channels in vivo by Ca2+\/calmodulin-dependent protein kinase II. J Clin Invest 116:2403\u20132412. https:\/\/doi.org\/10.1172\/JCI27918","journal-title":"J Clin Invest"},{"key":"2891_CR173","doi-asserted-by":"publisher","first-page":"9489","DOI":"10.1074\/jbc.M110.166546","volume":"286","author":"N Zaarour","year":"2011","unstructured":"Zaarour N, Defontaine N, Demaretz S, Azroyan A, Cheval L, Laghmani K (2011) Secretory carrier membrane protein 2 regulates exocytic insertion of NKCC2 into the cell membrane. J Biol Chem 286:9489\u20139502. https:\/\/doi.org\/10.1074\/jbc.M110.166546","journal-title":"J Biol Chem"},{"key":"2891_CR174","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1038\/385442a0","volume":"385","author":"GW Zamponi","year":"1997","unstructured":"Zamponi GW, Bourinet E, Nelson D, Nargeot J, Snutch TP (1997) Crosstalk between G proteins and protein kinase C mediated by the calcium channel alpha1 subunit. Nature 385:442\u2013446. https:\/\/doi.org\/10.1038\/385442a0","journal-title":"Nature"},{"key":"2891_CR175","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1038\/s41586-019-1801-3","volume":"576","author":"Y Zhao","year":"2019","unstructured":"Zhao Y, Huang G, Wu Q, Wu K, Li R, Lei J, Pan X, Yan N (2019) Cryo-EM structures of apo and antagonist-bound human Cav3.1. Nature 576:492\u2013497. https:\/\/doi.org\/10.1038\/s41586-019-1801-3","journal-title":"Nature"}],"container-title":["Pfl\u00fcgers Archiv - European Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-023-02891-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00424-023-02891-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-023-02891-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T04:54:35Z","timestamp":1705467275000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00424-023-02891-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,1]]},"references-count":175,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["2891"],"URL":"https:\/\/doi.org\/10.1007\/s00424-023-02891-z","relation":{},"ISSN":["0031-6768","1432-2013"],"issn-type":[{"value":"0031-6768","type":"print"},{"value":"1432-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,1]]},"assertion":[{"value":"27 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 November 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 December 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}