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Of note, it is often unquestioningly assumed to be muscle pain. To date, there has not been a study analyzing lumbar DOMS in terms of its pain origin, which was the aim of this study. Sixteen healthy individuals (L-DOMS) were enrolled for the present study and matched to participants from a previous study (<jats:italic>n<\/jats:italic>\u2009=\u200916, L-PAIN) who had undergone selective electrical stimulation of the thoracolumbar fascia and the multifidus muscle. DOMS was induced in the lower back of the L-DOMS group using eccentric trunk extensions performed until exhaustion. On subsequent days, pain on palpation (100-mm analogue scale), pressure pain threshold (PPT), and the Pain Sensation Scale (SES) were used to examine the sensory characteristics of DOMS. Pain on palpation showed a significant increase 24 and 48\u00a0h after eccentric training, whereas PPT was not affected (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). Factor analysis of L-DOMS and L-PAIN sensory descriptors (SES) yielded a stable three-factor solution distinguishing superficial thermal (\u201cheat pain \u201c) from superficial mechanical pain (\u201csharp pain\u201d) and \u201cdeep pain.\u201d \u201cHeat pain \u201c and \u201cdeep pain\u201d in L-DOMS were almost identical to sensory descriptors from electrical stimulation of fascial tissue (L-PAIN, all <jats:italic>p<\/jats:italic>\u2009&gt;\u20090.679) but significantly different from muscle pain (all <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.029). The differences in sensory description patterns as well as in PPT and self-reported DOMS for palpation pain scores suggest that DOMS has a fascial rather than a muscular origin.<\/jats:p>","DOI":"10.1007\/s00424-023-02896-8","type":"journal-article","created":{"date-parts":[[2023,12,16]],"date-time":"2023-12-16T03:01:42Z","timestamp":1702695702000},"page":"395-405","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Pain quality patterns in delayed onset muscle soreness of the lower back suggest sensitization of fascia rather than muscle afferents: a secondary analysis study"],"prefix":"10.1007","volume":"476","author":[{"given":"Andreas","family":"Brandl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Wilke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Egner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Schilder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Schleip","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,12,16]]},"reference":[{"key":"2896_CR1","doi-asserted-by":"publisher","first-page":"1080","DOI":"10.1016\/j.jpain.2011.05.006","volume":"12","author":"N Attal","year":"2011","unstructured":"Attal N, Perrot S, Fermanian J, Bouhassira D (2011) The neuropathic components of chronic low back pain: a prospective multicenter study using the DN4 questionnaire. 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