{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:01:58Z","timestamp":1740106918900,"version":"3.37.3"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["19K08426","23K08767"],"award-info":[{"award-number":["19K08426","23K08767"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008883","name":"Nagoya City University","doi-asserted-by":"publisher","award":["2213009"],"award-info":[{"award-number":["2213009"]}],"id":[{"id":"10.13039\/501100008883","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pflugers Arch - Eur J Physiol"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1007\/s00424-024-02990-5","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T11:01:37Z","timestamp":1721300497000},"page":"1555-1570","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Stress-induced impairment of parasympathetic NO-mediated inhibition of sympathetic vasoconstriction in submucosal arteriole of rat rectum"],"prefix":"10.1007","volume":"476","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2932-4693","authenticated-orcid":false,"given":"Retsu","family":"Mitsui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mizuki","family":"Yamori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0310-4927","authenticated-orcid":false,"given":"Hiroyuki","family":"Nakamori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3877-4349","authenticated-orcid":false,"given":"Hikaru","family":"Hashitani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,18]]},"reference":[{"key":"2990_CR1","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1113\/jphysiol.1983.sp014923","volume":"344","author":"PO Andersson","year":"1983","unstructured":"Andersson PO, Bloom SR, Edwards AV, J\u00e4rhult J, Mellander S (1983) Neural vasodilator control in the rectum of the cat and its possible mediation by vasoactive intestinal polypeptide. J Physiol 344:49\u201367","journal-title":"J Physiol"},{"key":"2990_CR2","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1111\/j.1476-5381.2010.01030.x","volume":"162","author":"J Blanco-Rivero","year":"2011","unstructured":"Blanco-Rivero J, de las Heras N, Mart\u00edn-Fern\u00e1ndez B, Cachofeiro V, Lahera V, Balfag\u00f3n G (2011) Rosuvastatin restored adrenergic and nitrergic function in mesenteric arteries from obese rats. Br J Pharmacol 162:271\u2013285","journal-title":"Br J Pharmacol"},{"key":"2990_CR3","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/0002-9610(69)90308-0","volume":"117","author":"SJ Boley","year":"1969","unstructured":"Boley SJ, Agrawal GP, Warren AR, Veith FJ, Levowitz BS, Treiber W, Dougherty J, Schwartz SS, Gliedman ML (1969) Pathophysiologic effects of bowel distention on intestinal blood flow. Am J Surg 117:228\u2013234","journal-title":"Am J Surg"},{"key":"2990_CR4","doi-asserted-by":"publisher","first-page":"G42","DOI":"10.1152\/ajpgi.00500.2004","volume":"289","author":"S Bradesi","year":"2005","unstructured":"Bradesi S, Schwetz I, Ennes HS, Lamy CM, Ohning G, Fanselow M, Pothoulakis C, McRoberts JA, Mayer EA (2005) Repeated exposure to water avoidance stress in rats: a new model for sustained visceral hyperalgesia. Am J Physiol Gastrointest Liver Physiol 289:G42\u2013G53","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"2990_CR5","doi-asserted-by":"publisher","first-page":"H1123","DOI":"10.1152\/ajpheart.01016.2011","volume":"302","author":"HH Chang","year":"2012","unstructured":"Chang HH, Lee YC, Chen MF, Kuo JS (2012) Lee TJ (2012) Sympathetic activation increases basilar arterial blood flow in normotensive but not hypertensive rats. Am J Physiol Heart Circ Physiol 302:H1123\u2013H1130","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2990_CR6","first-page":"H1350","volume":"262","author":"RY Chen","year":"1992","unstructured":"Chen RY, Li DS, Guth PH (1992) Role of calcitonin gene-related peptide in capsaicin-induced gastric submucosal arteriolar dilation. Am J Physiol 262:H1350\u2013H1355","journal-title":"Am J Physiol"},{"key":"2990_CR7","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S0002-9610(70)80139-8","volume":"20","author":"RF Edlich","year":"1970","unstructured":"Edlich RF, Borner JW, Kuphal J, Wangensteen OH (1970) Gastric blood flow. I. Its distribution during gastric distention. Am J Surg 20:35\u201337","journal-title":"Am J Surg"},{"key":"2990_CR8","first-page":"1","volume":"14","author":"MAP Fontes","year":"2023","unstructured":"Fontes MAP, Marins FR, Patel TA, de Paula CA, Dos Santos Machado LR, de Sousa Lima \u00c9B, Ventris-Godoy AC, Viana ACR, Linhares ICS, Xavier CH, Filosa JA, Patel KP (2023) Neurogenic background for emotional stress-associated hypertension. Curr Hypertens Rep 14:1\u201310","journal-title":"Curr Hypertens Rep"},{"key":"2990_CR9","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1679\/aohc.72.117","volume":"72","author":"T Fukutani","year":"2009","unstructured":"Fukutani T, Iino S, Nojyo Y (2009) The expression of soluble guanylate cyclase in the vasculature of rat skeletal muscle. Arch Histol Cytol 72:117\u2013126","journal-title":"Arch Histol Cytol"},{"key":"2990_CR10","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1038\/288373a0","volume":"288","author":"RF Furchgott","year":"1980","unstructured":"Furchgott RF, Zawadzki JV (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:373\u2013376","journal-title":"Nature"},{"key":"2990_CR11","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/S0165-1838(00)00127-2","volume":"81","author":"JB Furness","year":"2000","unstructured":"Furness JB (2000) Types of neurons in the enteric nervous system. J Auton Nerv Syst 81:87\u201396","journal-title":"J Auton Nerv Syst"},{"key":"2990_CR12","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1111\/nmo.12742","volume":"28","author":"DW Gil","year":"2016","unstructured":"Gil DW, Wang J, Gu C, Donello JE, Cabrera S, Al-Chaer ED (2016) Role of sympathetic nervous system in rat model of chronic visceral pain. Neurogastroenterol Motil 28:423\u2013431","journal-title":"Neurogastroenterol Motil"},{"key":"2990_CR13","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1161\/CIRCRESAHA.116.305697","volume":"116","author":"JE Hall","year":"2015","unstructured":"Hall JE, do Carmo JM, da Silva AA, Wang Z, Hall ME (2015) Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms. Circ Res 116:991\u20131006","journal-title":"Circ Res"},{"key":"2990_CR14","doi-asserted-by":"publisher","first-page":"2199","DOI":"10.1113\/JP285583","volume":"602","author":"H Hashitani","year":"2024","unstructured":"Hashitani H, Mitsui R, Hirai Y, Tanaka H, Miwa-Nishimura K (2024) Nitrergic inhibition of sympathetic arteriolar constrictions in the female rodent urethra. J Physiol 602:2199\u20132226","journal-title":"J Physiol"},{"key":"2990_CR15","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/BF00584711","volume":"398","author":"P Haupt","year":"1983","unstructured":"Haupt P, J\u00e4nig W, Kohler W (1983) Response pattern of visceral afferent fibres, supplying the colon, upon chemical and mechanical stimuli. Pflugers Arch 398:41\u201347","journal-title":"Pflugers Arch"},{"key":"2990_CR16","doi-asserted-by":"publisher","first-page":"3867","DOI":"10.1113\/jphysiol.2011.209478","volume":"589","author":"W Jiang","year":"2011","unstructured":"Jiang W, Kirkup AJ, Grundy D (2011) Mast cells drive mesenteric afferent signalling during acute intestinal ischaemia. J Physiol 589:3867\u20138382","journal-title":"J Physiol"},{"key":"2990_CR17","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1038\/s41581-018-0068-5","volume":"14","author":"AK Johnson","year":"2018","unstructured":"Johnson AK, Xue B (2018) Central nervous system neuroplasticity and the sensitization of hypertension. Nat Rev Nephrol 14:750\u2013766","journal-title":"Nat Rev Nephrol"},{"key":"2990_CR18","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1038\/hr.2010.48","volume":"33","author":"T Koyama","year":"2010","unstructured":"Koyama T, Hatanaka Y, Jin X, Yokomizo A, Fujiwara H, Goda M, Hobara N, Zamami Y, Kitamura Y, Kawasaki H (2010) Altered function of nitrergic nerves inhibiting sympathetic neurotransmission in mesenteric vascular beds of renovascular hypertensive rats. Hypertens Res 33:485\u2013491","journal-title":"Hypertens Res"},{"key":"2990_CR19","doi-asserted-by":"publisher","first-page":"104","DOI":"10.3109\/00365529309096054","volume":"28","author":"K Krohg-S\u00f8rensen","year":"1993","unstructured":"Krohg-S\u00f8rensen K, Lunde OC (1993) Perfusion of the human distal colon and rectum evaluated with endoscopic laser Doppler flowmetry. Methodologic aspects Scand J Gastroenterol 28:104\u2013108","journal-title":"Methodologic aspects Scand J Gastroenterol"},{"key":"2990_CR20","doi-asserted-by":"publisher","first-page":"108541","DOI":"10.1016\/j.exer.2021.108541","volume":"206","author":"C Li","year":"2021","unstructured":"Li C, Fitzgerald MEC, Del Mar N, Wang H, Haughey C, Honig MG, Reiner A (2021) Role of the superior salivatory nucleus in parasympathetic control of choroidal blood flow and in maintenance of retinal health. Exp Eye Res 206:108541","journal-title":"Exp Eye Res"},{"key":"2990_CR21","doi-asserted-by":"publisher","first-page":"729201","DOI":"10.3389\/fphys.2021.729201","volume":"12","author":"CF Louren\u00e7o","year":"2021","unstructured":"Louren\u00e7o CF, Laranjinha J (2021) Nitric oxide pathways in neurovascular coupling under normal and stress conditions in the brain: strategies to rescue aberrant coupling and improve cerebral blood flow. Front Physiol 12:729201","journal-title":"Front Physiol"},{"key":"2990_CR22","doi-asserted-by":"publisher","first-page":"888","DOI":"10.1152\/jappl.2002.92.2.888","volume":"92","author":"C Meyer","year":"2002","unstructured":"Meyer C, de Vries G, Davidge ST, Mayes DC (2002) Reassessing the mathematical modeling of the contribution of vasomotion to vascular resistance. J Appl Physiol 92:888\u2013889","journal-title":"J Appl Physiol"},{"key":"2990_CR23","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1007\/s00418-012-1074-5","volume":"140","author":"R Mitsui","year":"2013","unstructured":"Mitsui R, Hashitani H (2013) Immunohistochemical characteristics of suburothelial microvasculature in the mouse bladder. Histochem Cell Biol 140:189\u2013200","journal-title":"Histochem Cell Biol"},{"key":"2990_CR24","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1007\/s00424-014-1576-1","volume":"467","author":"R Mitsui","year":"2015","unstructured":"Mitsui R, Hashitani H (2015) Functional properties of submucosal venules in the rat stomach. Pflugers Arch 467:1327\u20131342","journal-title":"Pflugers Arch"},{"key":"2990_CR25","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1007\/s00441-021-03521-9","volume":"386","author":"R Mitsui","year":"2021","unstructured":"Mitsui R, Chikada Y, Arai K, Hashitani H (2021) Functional nitrergic innervation of smooth muscle structures in the mucosa of pig lower urinary tract. Cell Tissue Res 386:513\u2013531","journal-title":"Cell Tissue Res"},{"key":"2990_CR26","doi-asserted-by":"publisher","first-page":"5213","DOI":"10.1113\/JP284284","volume":"601","author":"R Mitsui","year":"2023","unstructured":"Mitsui R, Miwa-Nishimura K, Hashitani H (2023) Roles of endothelial prostaglandin I2 in maintaining synchronous spontaneous Ca2+ transients in rectal capillary pericytes. J Physiol 601:5213\u20135240","journal-title":"J Physiol"},{"key":"2990_CR27","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1053\/j.gastro.2004.08.057","volume":"127","author":"CD Murray","year":"2004","unstructured":"Murray CD, Flynn J, Ratcliffe L, Jacyna MR, Kamm MA, Emmanuel AV (2004) Effect of acute physical and psychological stress on gut autonomic innervation in irritable bowel syndrome. Gastroenterology 127:1695\u20131703","journal-title":"Gastroenterology"},{"key":"2990_CR28","first-page":"48","volume":"26","author":"TO Neild","year":"1989","unstructured":"Neild TO (1989) Measurement of arteriole diameter changes by analysis of television images. Blood Vessels 26:48\u201352","journal-title":"Blood Vessels"},{"key":"2990_CR29","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1113\/jphysiol.1990.sp017910","volume":"420","author":"TO Neild","year":"1990","unstructured":"Neild TO, Shen KZ, Surprenant A (1990) Vasodilatation of arterioles by acetylcholine released from single neurones in the guinea-pig submucosal plexus. J Physiol 420:247\u2013265","journal-title":"J Physiol"},{"key":"2990_CR30","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1002\/cne.20965","volume":"496","author":"C Olsson","year":"2006","unstructured":"Olsson C, Chen BN, Jones S, Chataway TK, Costa M, Brookes SJ (2006) Comparison of extrinsic efferent innervation of guinea pig distal colon and rectum. J Comp Neurol 496:787\u2013801","journal-title":"J Comp Neurol"},{"key":"2990_CR31","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1113\/jphysiol.1996.sp021350","volume":"492","author":"HL Pan","year":"1996","unstructured":"Pan HL, Longhurst JC (1996) Ischaemia-sensitive sympathetic afferents innervating the gastrointestinal tract function as nociceptors in cats. J Physiol 492:841\u2013850","journal-title":"J Physiol"},{"key":"2990_CR32","doi-asserted-by":"publisher","first-page":"4893","DOI":"10.1113\/JP274269","volume":"595","author":"J Park","year":"2017","unstructured":"Park J, Marvar PJ, Liao P, Kankam ML, Norrholm SD, Downey RM, McCullough SA, Le NA, Rothbaum BO (2017) Baroreflex dysfunction and augmented sympathetic nerve responses during mental stress in veterans with post-traumatic stress disorder. J Physiol 595:4893\u20134908","journal-title":"J Physiol"},{"key":"2990_CR33","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1161\/01.RES.77.4.841","volume":"77","author":"P Schwarz","year":"1995","unstructured":"Schwarz P, Diem R, Dun NJ, F\u00f6rstermann U (1995) Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves. Circ Res 77:841\u2013848","journal-title":"Circ Res"},{"key":"2990_CR34","first-page":"1073","volume":"178","author":"H Tanaka","year":"2021","unstructured":"Tanaka H, Mitsui R, Oishi M, Passlick S, Jabs R, Steinh\u00e4user C, Tanaka KF, Hashitani H (2021) NO-mediated signal transmission in bladder vasculature as a therapeutic target of PDE5 inhibitors. Rodent model studies Br J Pharmacol 178:1073\u20131094","journal-title":"Rodent model studies Br J Pharmacol"},{"key":"2990_CR35","first-page":"H1511","volume":"259","author":"N Toda","year":"1990","unstructured":"Toda N, Okamura T (1990) Mechanism underlying the response to vasodilator nerve stimulation in isolated dog and monkey cerebral arteries. Am J Physiol 259:H1511\u2013H1517","journal-title":"Am J Physiol"},{"key":"2990_CR36","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1097\/00004647-200004000-00007","volume":"20","author":"N Toda","year":"2000","unstructured":"Toda N, Ayajiki K, Tanaka T, Okamura T (2000) Preganglionic and postganglionic neurons responsible for cerebral vasodilation mediated by nitric oxide in anesthetized dogs. J Cereb Blood Flow Metab 20:700\u2013708","journal-title":"J Cereb Blood Flow Metab"},{"key":"2990_CR37","doi-asserted-by":"crossref","first-page":"G650","DOI":"10.1152\/ajpcell.1994.267.2.C650","volume":"267","author":"S Vanner","year":"1994","unstructured":"Vanner S (1994) Corelease of neuropeptides from capsaicin-sensitive afferents dilates submucosal arterioles in guinea pig ileum. Am J Physiol 267:G650\u2013G655","journal-title":"Am J Physiol"},{"issue":"Suppl 1","key":"2990_CR38","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1111\/j.1743-3150.2004.00473.x","volume":"16","author":"S Vanner","year":"2004","unstructured":"Vanner S, MacKnoughton WK (2004) Submucosal secretomotor and vasodilator reflexes. Neurogastroenterol Motil 16(Suppl 1):39\u201343","journal-title":"Neurogastroenterol Motil"},{"key":"2990_CR39","first-page":"G136","volume":"261","author":"S Vanner","year":"1991","unstructured":"Vanner S, Surprenant A (1991) Cholinergic and noncholinergic submucosal neurons dilate arterioles in guinea pig colon. Am J Physiol 261:G136\u2013G144","journal-title":"Am J Physiol"},{"key":"2990_CR40","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1016\/0031-9384(91)90567-8","volume":"50","author":"RJ Viken","year":"1991","unstructured":"Viken RJ, Johnson AK, Knutson JF (1991) Blood pressure, heart rate, and regional resistance in behavioral defense. Physiol Behav 50:1097\u20131101","journal-title":"Physiol Behav"},{"key":"2990_CR41","doi-asserted-by":"publisher","first-page":"3547","DOI":"10.1073\/pnas.93.8.3547","volume":"93","author":"E Weihe","year":"1996","unstructured":"Weihe E, Tao-Cheng JH, Sch\u00e4fer MK, Erickson JD, Eiden LE (1996) Visualization of the vesicular acetylcholine transporter in cholinergic nerve terminals and its targeting to a specific population of small synaptic vesicles. Proc Natl Acad Sci U S A 93:3547\u20133552","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2990_CR42","doi-asserted-by":"publisher","first-page":"e14317","DOI":"10.1111\/nmo.14317","volume":"34","author":"F Yuan","year":"2022","unstructured":"Yuan F, Ren H, Tan W, Wang Y, Luo H (2022) Effect of phosphodiesterase-4 inhibitor rolipram on colonic hypermotility in water avoidance stress rat model. Neurogastroenterol Motil 34:e14317","journal-title":"Neurogastroenterol Motil"}],"container-title":["Pfl\u00fcgers Archiv - European Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-024-02990-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00424-024-02990-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00424-024-02990-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T15:07:21Z","timestamp":1725894441000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00424-024-02990-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,18]]},"references-count":42,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["2990"],"URL":"https:\/\/doi.org\/10.1007\/s00424-024-02990-5","relation":{},"ISSN":["0031-6768","1432-2013"],"issn-type":[{"type":"print","value":"0031-6768"},{"type":"electronic","value":"1432-2013"}],"subject":[],"published":{"date-parts":[[2024,7,18]]},"assertion":[{"value":"31 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 June 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 July 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The experimental protocols in the present study were approved by the animal experimentation ethics committee of Nagoya City University Graduate School of Medical Sciences (approval no.; 21\u2013002).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"There is no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}