{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:56:21Z","timestamp":1760061381612},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1996,7,1]],"date-time":"1996-07-01T00:00:00Z","timestamp":836179200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pflugers Arch - Eur J Physiol"],"published-print":{"date-parts":[[1996,7]]},"DOI":"10.1007\/s004240050167","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T08:36:27Z","timestamp":1030264587000},"page":"538-545","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Changes in element concentrations induced by agonist in pig pancreatic acinar cells"],"prefix":"10.1007","volume":"432","author":[{"given":"Sadao","family":"Sasaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikuko","family":"Nakagaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiki","family":"Hori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisao","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"64320538424_CR1","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/361315a0","volume":"361","author":"MJ Berridge","year":"1993","unstructured":"Berridge MJ (1993) Inositol trisphosphate and calcium signalling. Nature 361:315\u2013325","journal-title":"Nature"},{"key":"64320538424_CR2","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1113\/jphysiol.1956.sp005500","volume":"132","author":"AS Burgen","year":"1956","unstructured":"Burgen AS (1956) The secretion of potassium in saliva. J Physiol (Lond) 132:20\u201339","journal-title":"J Physiol (Lond)"},{"key":"64320538424_CR3","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/BF01869469","volume":"110","author":"DI Cook","year":"1989","unstructured":"Cook DI, Young JA (1989) Effect of K+ channels in the apical plasma membrane on epithelial secretion based on secondary active Cl transport. J Membr Biol 110:139\u2013146","journal-title":"J Membr Biol"},{"key":"64320538424_CR4","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF00581153","volume":"373","author":"A D\u00f6rge","year":"1978","unstructured":"D\u00f6rge A, Rick R, Gehring K, Thurau K (1978) Preparation of freeze-dried cryosections for quantitative X-ray microanalysis of electrolytes in biological soft tissues. Pfl\u00fcgers Arch 373:85\u201397","journal-title":"Pfl\u00fcgers Arch"},{"key":"64320538424_CR5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0092-8674(00)81292-1","volume":"84","author":"OV Gerasimenko","year":"1996","unstructured":"Gerasimenko OV, Gerasimenko JV, Belan PV, Petersen OH (1996) Inositol trisphosphate and cyclic ADP-ribose-mediated release of Ca2+ from single isolated pancreatic zymogen granules. Cell 84:473\u2013480","journal-title":"Cell"},{"key":"64320538424_CR6","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1152\/physrev.1985.65.3.760","volume":"65","author":"R Greger","year":"1985","unstructured":"Greger R (1985) Ion transport mechanisms in thick ascending limb of Henle\u2019s loop of mammalian nephron. Physiol Rev 65:760\u2013797","journal-title":"Physiol Rev"},{"key":"64320538424_CR7","first-page":"379","volume":"5","author":"BL Gupta","year":"1991","unstructured":"Gupta BL (1991) Ted Hall and science of biological micro-probe X-ray analysis: a historical perspective of methodology and biological dividends. Scan Microsc 5:379\u2013426","journal-title":"Scan Microsc"},{"key":"64320538424_CR8","first-page":"R176","volume":"244","author":"BL Gupta","year":"1983","unstructured":"Gupta BL, Hall A (1983) Ionic distribution in dopamine-stimulated NaCl fluid-secreting cockroach salivary glands. Am J Physiol 244:R176-R186","journal-title":"Am J Physiol"},{"key":"64320538424_CR9","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1242\/jeb.72.1.261","volume":"72","author":"BL Gupta","year":"1978","unstructured":"Gupta BL, Berridge MJ, Hall TA, Moreton RB (1978) Electron microprobe and ion-selective microelectrode studies of fluid secretion in the salivary glands of Calliphora. J Exp Biol 72:261\u2013284","journal-title":"J Exp Biol"},{"key":"64320538424_CR10","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1113\/jphysiol.1986.sp016328","volume":"381","author":"KT Izutsu","year":"1986","unstructured":"Izutsu KT, Johnson DE (1986) Changes in elemental concentrations of rat parotid acinar cells following pilocarpine stimulation. J Physiol (Lond) 381:297\u2013309","journal-title":"J Physiol (Lond)"},{"key":"64320538424_CR11","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1748-1716.1981.tb06730.x","volume":"111","author":"SL Jensen","year":"1981","unstructured":"Jensen SL, Rehfeld JF, Holst JJ, Nielsen OV, Fahrenkrug GT, Schaffalitzky OB (1981) Secretory effects of cholecystokinin on the isolated perfused porcine pancreas. Acta Physiol Scand 111:225\u2013231","journal-title":"Acta Physiol Scand"},{"key":"64320538424_CR12","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1038\/348735a0","volume":"348","author":"H Kasai","year":"1990","unstructured":"Kasai H, Augustine GJ (1990) Cytosolic Ca2+ gradients triggering unidirectional fluid secretion from exocrine pancreas. Nature 348:735\u2013738","journal-title":"Nature"},{"key":"64320538424_CR13","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/0092-8674(93)90514-Q","volume":"74","author":"H Kasai","year":"1993","unstructured":"Kasai H, Li YX, Miyashita Y (1993) Subcellular distribution of Ca2+ release channels underlying Ca2+ waves and oscillations in exocrine pancreas. Cell 74:669\u2013677","journal-title":"Cell"},{"key":"64320538424_CR14","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1152\/ajplegacy.1971.221.2.496","volume":"221","author":"JA Mangos","year":"1971","unstructured":"Mangos JA, Mcsherry NR (1971) Micropuncture study of excretion of water and electrolytes by the pancreas. Am J Physiol 221:496\u2013503","journal-title":"Am J Physiol"},{"key":"64320538424_CR15","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1113\/jphysiol.1984.sp015501","volume":"357","author":"A Marty","year":"1984","unstructured":"Marty A, Tan YP, Trautmann A (1984) Three types of calcium-dependent channel in rat lacrimal glands. J Physiol (Lond) 357:293\u2013325","journal-title":"J Physiol (Lond)"},{"key":"64320538424_CR16","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/299159a0","volume":"299","author":"Y Maruyama","year":"1982","unstructured":"Maruyama Y, Petersen OH (1982) Single-channel currents in isolated patches of plasma membrane from basal surface of pancreatic acini. Nature 299:159\u2013161","journal-title":"Nature"},{"key":"64320538424_CR17","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/305228a0","volume":"305","author":"Y Maruyama","year":"1983","unstructured":"Maruyama Y, Petersen OH, Flanagan P, Person GT (1983) Quantification of Ca2+-activated K+ channels under hormonal control in pig pancreas acinar cells. Nature 305:228\u2013232","journal-title":"Nature"},{"key":"64320538424_CR18","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1007\/BF00584333","volume":"401","author":"I Nakagaki","year":"1984","unstructured":"Nakagaki I, Sasaki S, Shiguma M, Imai Y (1984) Distribution of elements in the pancreatic exocrine cells determined by electron probe X-ray microanalysis. Pfl\u00fcgers Arch 401:340\u2013345","journal-title":"Pfl\u00fcgers Arch"},{"key":"64320538424_CR19","doi-asserted-by":"crossref","first-page":"C177","DOI":"10.1152\/ajpcell.1987.253.2.C177","volume":"253","author":"SM O\u2019Grady","year":"1987","unstructured":"O\u2019Grady SM, Palfrey HC, Field M (1987) Characteristics and functions of Na-K-Cl cotransport in epithelial tissues. Am J Physiol 253:C177-C192","journal-title":"Am J Physiol"},{"key":"64320538424_CR20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1113\/jphysiol.1992.sp019028","volume":"448","author":"OH Petersen","year":"1992","unstructured":"Petersen OH (1992) Stimulus-secretion coupling: cytoplasmic calcium signals and the control of ion channels in exocrine acinar cells. J Physiol (Lond) 448:1\u201351","journal-title":"J Physiol (Lond)"},{"key":"64320538424_CR21","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1152\/ajplegacy.1968.215.1.34","volume":"215","author":"HA Reber","year":"1968","unstructured":"Reber HA, Wolf LJ (1968) Micropuncture study of pancreatic electrolyte secretion. Am J Physiol 215:34\u201340","journal-title":"Am J Physiol"},{"key":"64320538424_CR22","doi-asserted-by":"crossref","first-page":"69","DOI":"10.2170\/jjphysiol.33.69","volume":"33","author":"S Sasaki","year":"1983","unstructured":"Sasaki S, Nakagaki I, Mori H, Imai Y (1983) Intracellular calcium store and transport of elements in acinar cells of the salivary gland determined by electron probe X-ray microanalysis. Jpn J Physiol 33:69\u201383","journal-title":"Jpn J Physiol"},{"issue":"2","key":"64320538424_CR23","first-page":"199","volume":"7","author":"S Sasaki","year":"1986","unstructured":"Sasaki S, Nakagaki I, Tanaka H, Michigami M, Imai Y (1986) Ion and exocytosis of pig pancreatic acinar cells studied by electron probe X-ray microanalysis and high voltage electron microscopy. Biomed Res 7 [Suppl 2]:199\u2013202","journal-title":"Biomed Res"},{"key":"64320538424_CR24","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1006\/jmcc.1994.1124","volume":"26","author":"S Sasaki","year":"1994","unstructured":"Sasaki S, Sawada Y, Morita M, Hikita Y, Nakagaki I, Hori S, Sasaki S, Takeuchi A (1994) Effects of a benzothiazepine calcium blocker on electrolyte alteration in human ischemic and reperfused myocardium. J Mol Cell Cardiol 26:1037\u20131044","journal-title":"J Mol Cell Cardiol"},{"key":"64320538424_CR25","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/BF00586559","volume":"308","author":"I Schulz","year":"1969","unstructured":"Schulz I, Yamagata A, Weske M (1969) Micropuncture studies on the pancreas of the rabbit. Pfl\u00fcgers Arch 308:277\u2013290","journal-title":"Pfl\u00fcgers Arch"},{"key":"64320538424_CR26","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0005-2736(84)90237-2","volume":"775","author":"J Singh","year":"1984","unstructured":"Singh J (1984) Effects of acetylcholine and caerulein on 86Rb+ efflux in the mouse pancreas. Evidence for sodium-potassiumchloride cotransport system. Biochim Biophys Acta 775:77\u201385","journal-title":"Biochim Biophys Acta"},{"key":"64320538424_CR27","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/306067a0","volume":"306","author":"H Streb","year":"1983","unstructured":"Streb H, Irvine RF, Berridge MJ, Schultz I (1983) Release of Ca2+ from a non-mitochondrial intracellular store of pancreatic acinar cells by inositol 1,4,5-trisphosphate. Nature 306:67\u201369","journal-title":"Nature"},{"key":"64320538424_CR28","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1085\/jgp.62.4.407","volume":"62","author":"CH Swanson","year":"1973","unstructured":"Swanson CH, Solomon AK (1973) A micropuncture investigation of the whole tissue mechanism of electrolyte secretion by the in vitro rabbit pancreas. J Gen Physiol 62:407\u2013429","journal-title":"J Gen Physiol"},{"key":"64320538424_CR29","doi-asserted-by":"crossref","first-page":"11229","DOI":"10.1073\/pnas.89.23.11229","volume":"89","author":"YP Tan","year":"1992","unstructured":"Tan YP, Marty A, Trautmann A (1992) High density of Ca2+ dependent K+ and Cl\u2212 channels on the luminal membrane of lacrimal acinar cells. Proc Natl Acad Sci USA 89:11229\u201311233","journal-title":"Proc Natl Acad Sci USA"},{"key":"64320538424_CR30","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/0092-8674(93)90513-P","volume":"74","author":"P Thorn","year":"1993","unstructured":"Thorn P, Lawrie AM, Smith PM, Gallacher DV, Petersen OH (1993) Local and global cytosolic Ca2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate. Cell 74:661\u2013668","journal-title":"Cell"},{"key":"64320538424_CR31","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1073\/pnas.81.2.611","volume":"81","author":"A Trautmann","year":"1984","unstructured":"Trautmann A, Marty A (1984) Activation of Ca2+-dependent K+ channels by carbamylcholine in rat lacrimal glands. Proc Natl Acad Sci USA 81:611\u2013615","journal-title":"Proc Natl Acad Sci USA"},{"key":"64320538424_CR32","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/0014-4800(85)90064-4","volume":"63","author":"AM Euler Von","year":"1985","unstructured":"Von Euler AM, Ceder O, Kollberg H, Roomans GM (1985) Effect of chronic treatment with cystic fibrosis fibroblast medium on rat submandibular gland cells. Exp Mol Pathol 63:142\u2013149","journal-title":"Exp Mol Pathol"},{"key":"64320538424_CR33","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/0092-8674(90)90505-9","volume":"63","author":"M Wakui","year":"1990","unstructured":"Wakui M, Osipchuk YV, Petersen OH (1990) Receptor-activated cytoplasmic Ca2+ spiking mediated by inositol trisphosphate is due to Ca2+-induced Ca2+ release. Cell 63:1025\u20131035","journal-title":"Cell"},{"key":"64320538424_CR34","first-page":"H917","volume":"255","author":"LG Walsh","year":"1988","unstructured":"Walsh LG, Tormey JM (1988) Subcellular electrolyte shifts during in vitro myocardial ischemia and reperfusion. Am J Physiol 255:H917-H928","journal-title":"Am J Physiol"},{"key":"64320538424_CR35","doi-asserted-by":"crossref","first-page":"13446","DOI":"10.1016\/S0021-9258(18)77367-5","volume":"265","author":"SH Yoo","year":"1990","unstructured":"Yoo SH, Albanesi JP (1990) Inositol 1,4,5-trisphosphate-triggered Ca2+ release from bovine adrenal medullary secretory vesicles. J Biol Chem 265:13446\u201313448.","journal-title":"J Biol Chem"},{"key":"64320538424_CR36","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF00362654","volume":"291","author":"JA Young","year":"1966","unstructured":"Young JA, Sch\u00f6gel E (1966) Micropuncture investigation of sodium and potassium excretion in rat submaxillary saliva. Pfl\u00fcgers Arch 291:85\u201398","journal-title":"Pfl\u00fcgers Arch"},{"key":"64320538424_CR37","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/jemt.1060090107","volume":"9","author":"K Zierold","year":"1988","unstructured":"Zierold K (1988) X-ray microanalysis of freeze-dried and frozen-hydrated cryosections. J Electron Microsc Tech 9:65\u201382","journal-title":"J Electron Microsc Tech"}],"container-title":["Pfl\u00fcgers Archiv - European Journal of Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s004240050167.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s004240050167\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s004240050167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T11:54:32Z","timestamp":1620042872000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s004240050167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,7]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1996,7]]}},"alternative-id":["64320538424"],"URL":"https:\/\/doi.org\/10.1007\/s004240050167","relation":{},"ISSN":["0031-6768","1432-2013"],"issn-type":[{"value":"0031-6768","type":"print"},{"value":"1432-2013","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,7]]}}}