{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T03:14:44Z","timestamp":1783307684079,"version":"3.54.6"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2015,11,27]],"date-time":"2015-11-27T00:00:00Z","timestamp":1448582400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"CONACYT","award":["201448, 152793"],"award-info":[{"award-number":["201448, 152793"]}]},{"DOI":"10.13039\/501100006087","name":"Direcci\u00f3n General Asuntos del Personal Acad\u00e9mico, Universidad Nacional Aut\u00f3noma de M\u00e9xico (MX)","doi-asserted-by":"publisher","award":["IG-200414"],"award-info":[{"award-number":["IG-200414"]}],"id":[{"id":"10.13039\/501100006087","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Planta"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1007\/s00425-015-2431-0","type":"journal-article","created":{"date-parts":[[2015,11,27]],"date-time":"2015-11-27T04:21:47Z","timestamp":1448598107000},"page":"675-685","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Towards the development of an oral vaccine against porcine cysticercosis: expression of the protective HP6\/TSOL18 antigen in transgenic carrots cells"],"prefix":"10.1007","volume":"243","author":[{"given":"Elizabeth","family":"Monreal-Escalante","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dania O.","family":"Govea-Alonso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisela","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacquelynne","family":"Cervantes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge A.","family":"Salazar-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Romero-Maldonado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Rosas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Garate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gladis","family":"Fragoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edda","family":"Sciutto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Rosales-Mendoza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,11,27]]},"reference":[{"key":"2431_CR1","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.ijpara.2010.01.006","volume":"40","author":"E Assana","year":"2010","unstructured":"Assana E, Kyngdon CT, Gauci CG, Geerts S, Dorny P, De Deken R (2010) Elimination of Taenia solium transmission to pigs in a field trial of the HP6\/TSOL18 vaccine in Cameroon. Int J Parasitol 40:515\u2013519","journal-title":"Int J Parasitol"},{"key":"2431_CR2","doi-asserted-by":"crossref","first-page":"e4792","DOI":"10.1371\/journal.pone.0004792","volume":"4","author":"D Aviezer","year":"2009","unstructured":"Aviezer D, Brill-Almon E, Shaaltiel Y, Hashmueli S, Bartfeld D, Mizrachi S, Liberman Y, Freeman A, Zimran A, Galun E (2009) A plant-derived recombinant human glucocerebrosidase enzyme\u2014a preclinical and phase I investigation. PLoS One 4:e4792","journal-title":"PLoS One"},{"issue":"5 Suppl","key":"2431_CR3","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/nm0598supp-487","volume":"4","author":"A Batson","year":"1998","unstructured":"Batson A (1998) Win\u2013win interactions between the public and private sectors. Nat Med 4(5 Suppl):487\u2013491","journal-title":"Nat Med"},{"key":"2431_CR4","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0166-6851(96)02610-2","volume":"78","author":"L Benitez","year":"1996","unstructured":"Benitez L, Garate T, Harrison LJ, Kirkham P, Brookes SM, Parkhouse RM (1996) Cloning and sequencing of the gene encoding the principal 18-kDa a secreted antigen of activated oncospheres of Taenia saginata. Mol Biochem Parasitol 78:265\u2013268","journal-title":"Mol Biochem Parasitol"},{"key":"2431_CR5","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1586\/14760584.3.5.557","volume":"3","author":"S Berman","year":"2004","unstructured":"Berman S, Giffin RB (2004) Global perspectives on vaccine financing. Expert Rev Vaccines 3:557\u2013562","journal-title":"Expert Rev Vaccines"},{"key":"2431_CR6","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.1016\/j.vaccine.2012.02.022","volume":"30","author":"MA Betancourt","year":"2012","unstructured":"Betancourt MA, de Aluja AS, Sciutto E, Hern\u00e1ndez M, Bobes RJ, Rosas G, Hern\u00e1ndez B, Fragoso G, Hallal-Calleros C, Aguilar L, Flores-Per\u00e9z I (2012) Effective protection induced by three different versions of the porcine S3Pvac anticysticercosis vaccine against rabbit experimental Taenia pisiformis cysticercosis. Vaccine 30:2760\u20132767","journal-title":"Vaccine"},{"key":"2431_CR7","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1128\/IAI.00444-07","volume":"76","author":"X Cai","year":"2008","unstructured":"Cai X, Yuan G, Zheng Y, Luo X, Zhang S, Ding J, Jing Z, Lu C (2008) Effective production and purification of the glycosylated TSOL18 antigen, which is protective against pig cysticercosis. Infect Immun 76:767\u2013770","journal-title":"Infect Immun"},{"issue":"9","key":"2431_CR8","doi-asserted-by":"crossref","first-page":"e107180","DOI":"10.1371\/journal.pone.0107180","volume":"9","author":"N Dabral","year":"2014","unstructured":"Dabral N, Moreno-Lafont M, Sriranganathan N, Vemulapalli R (2014) Oral immunization of mice with gamma-irradiated Brucella neotomae induces protection against intraperitoneal and intranasal challenge with virulent B. abortus 2308. PLoS One 9(9):e107180","journal-title":"PLoS One"},{"key":"2431_CR9","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1002\/biot.200600145","volume":"1","author":"H Daniell","year":"2006","unstructured":"Daniell H (2006) Production of biopharmaceuticals and vaccines in plants via the chloroplast genome. Biotechnol J 1:1071\u20131079","journal-title":"Biotechnol J"},{"key":"2431_CR10","doi-asserted-by":"crossref","first-page":"368","DOI":"10.2174\/156802608783790794","volume":"8","author":"AS Aluja De","year":"2008","unstructured":"De Aluja AS (2008) Cysticercosis in the pig. Curr Trop Med Chem 8:368\u2013374","journal-title":"Curr Trop Med Chem"},{"key":"2431_CR11","doi-asserted-by":"crossref","first-page":"259","DOI":"10.21149\/spm.v56i3.7343","volume":"56","author":"AS Aluja De","year":"2014","unstructured":"De Aluja AS, Su\u00e1rez-Mar\u00edn R, Sciutto-Conde E, Morales-Soto J, Mart\u00ednez-Maya JJ, Villalobos N (2014) Evaluation of the impact of a control program against taeniasis-cysticercosis (Taenia solium). Salud Publica Mex 56:259\u2013265","journal-title":"Salud Publica Mex"},{"key":"2431_CR12","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/BF02712670","volume":"1","author":"SL Dellaporta","year":"1983","unstructured":"Dellaporta SL, Wood J, Hicks JB (1983) A plant DNA minipreparation: version II. Plant Mol Biol Rep 1:19\u201321","journal-title":"Plant Mol Biol Rep"},{"key":"2431_CR13","doi-asserted-by":"crossref","first-page":"5292","DOI":"10.1128\/IAI.72.9.5292-5297.2004","volume":"72","author":"A Flisser","year":"2004","unstructured":"Flisser A, Gauci CG, Zoli A, Martinez-Ocana J, Garza-Rodriguez A, Dominguez-Alpizar JL, Maravilla P, Rodriguez-Canul R, \u00c1vila G, Aguilar-Vega L, Kyngdon C, Geerts S, Lightowlers MW (2004) Induction of protection against porcine cysticercosis by vaccination with recombinant oncosphere antigens. Infect Immun 72:5292\u20135297","journal-title":"Infect Immun"},{"key":"2431_CR14","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1128\/CVI.05030-11","volume":"18","author":"G Fragoso","year":"2011","unstructured":"Fragoso G, Esquivel-Guadarrama F, Santana MA, Bobes RJ, Hern\u00e1ndez B, Cervantes J, Segura R, Goldbaum FA, Sciutto E, Rosas G (2011) Heterologous prime-boost oral immunization with GK1 peptide from Taenia crassiceps cysticerci induces protective immunity. Clin Vaccine Immunol 18:1067\u20131076","journal-title":"Clin Vaccine Immunol"},{"key":"2431_CR15","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.vaccine.2013.01.036","volume":"31","author":"G Gandhi","year":"2013","unstructured":"Gandhi G, Lydonb P, Cornejoc S, Brenzel L, Wrobel S, Chang H (2013) Projections of costs, financing, and additional resource requirements for low- and lower middle-income country immunization programs over the decade, 2011\u20132020. Vaccine 31:137\u2013148","journal-title":"Vaccine"},{"key":"2431_CR16","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S1474-4422(05)70194-0","volume":"4","author":"HH Garcia","year":"2005","unstructured":"Garcia HH, Del Brutto OH, Cysticercosis Working Group in Peru (2005) Neurocysticercosis: updated concepts about an old disease. Lancet Neurol 4:653\u2013661","journal-title":"Lancet Neurol"},{"key":"2431_CR17","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S0020-7519(98)00034-4","volume":"28","author":"CG Gauci","year":"1998","unstructured":"Gauci CG, Flisser A, Lightowlers MW (1998) Taenia solium oncosphere protein homologous to host-protective Taenia ovis and Taenia saginata 18\u00a0kDa antigens. Int J Parasitol 28:757\u2013760","journal-title":"Int J Parasitol"},{"key":"2431_CR18","first-page":"e52459","volume":"97","author":"E Gecchele","year":"2015","unstructured":"Gecchele E, Merlin M, Brozzetti A, Falorni A, Pezzotti M, Avesani L (2015) A comparative analysis of recombinant protein expression in different biofactories: bacteria, insect cells and plant systems. J Vis Exp 97:e52459. doi: 10.3791\/52459","journal-title":"J Vis Exp"},{"key":"2431_CR19","doi-asserted-by":"crossref","first-page":"837","DOI":"10.4269\/ajtmh.2005.72.837","volume":"72","author":"AE Gonzalez","year":"2005","unstructured":"Gonzalez AE, Gauci CG, Barber D, Gilman RH, Tsang VC, Garcia HH, Verastegui M, Lightowlers MW (2005) Vaccination of pigs to control human neurocysticercosis. Am J Trop Med Hyg 72:837\u2013839","journal-title":"Am J Trop Med Hyg"},{"key":"2431_CR20","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0020-7519(95)00097-6","volume":"26","author":"GB Harrison","year":"1996","unstructured":"Harrison GB, Heath DD, Dempster RP, Gauci C, Newton SE, Cameron WG, Robinson CM, Lawrence SB, Lightowlers MW, Rickard MD (1996) Identification and cDNA cloning of two novel low molecular weight host-protective antigens from Taenia ovis oncospheres. Int J Parasitol 26:195\u2013204","journal-title":"Int J Parasitol"},{"key":"2431_CR21","doi-asserted-by":"crossref","first-page":"4252","DOI":"10.1016\/j.vaccine.2007.02.080","volume":"25","author":"M Hern\u00e1ndez","year":"2007","unstructured":"Hern\u00e1ndez M, Cabrera-Ponce JL, Fragoso G, L\u00f3pez-Casillas F, Guevara-Garc\u00eda A, Rosas G, Le\u00f3n-Ram\u00edrez C, Ju\u00e1rez P, S\u00e1nchez-Garc\u00eda G, Cervantes J, Acero G, Toledo A, Cruz C, Bojalil R, Herrera-Estrella L, Sciutto E (2007) A new highly effective anticysticercosis vaccine expressed in transgenic papaya. Vaccine 25:4252\u20134260","journal-title":"Vaccine"},{"key":"2431_CR22","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1586\/14760584.2014.953064","volume":"13","author":"M Hern\u00e1ndez","year":"2014","unstructured":"Hern\u00e1ndez M, Rosas G, Cervantes J, Fragoso G, Rosales-Mendoza S, Sciutto E (2014) Transgenic plants: a 5-year update on oral antipathogen vaccine development. Expert Rev Vaccines 13:1523\u20131536","journal-title":"Expert Rev Vaccines"},{"key":"2431_CR23","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S0264-410X(01)00249-3","volume":"20","author":"M Huerta","year":"2001","unstructured":"Huerta M, De Aluja AS, Fragoso G, Toledo A, Villalobos N, Hern\u00e1ndez M, Gevorkian G, Acero G, Diaz A, Alvarez I, Avila R, Beltran C, Garcia G, Martinez JJ, Larralde C, Sciutto E (2001) Synthetic peptide vaccine against Taenia solium pig cysticercosis: successful vaccination in a controlled field trial in rural Mexico. Vaccine 20:262\u2013266","journal-title":"Vaccine"},{"key":"2431_CR24","doi-asserted-by":"crossref","first-page":"7475","DOI":"10.1016\/j.vaccine.2012.10.057","volume":"30","author":"CM Jayashi","year":"2012","unstructured":"Jayashi CM, Gonzalez AE, Castillo Neyra R, Kyngdon CT, Gauci CG, Lightowlers MW (2012) Characterisation of antibody responses in pigs induced by recombinant oncosphere antigens from Taenia solium. Vaccine 30:7475\u20137480","journal-title":"Vaccine"},{"key":"2431_CR25","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1111\/j.1365-313X.2007.03183.x","volume":"51","author":"SI Kim","year":"2007","unstructured":"Kim SI, Veena JH, Gelvin SB (2007) Genome-wide analysis of Agrobacterium T-DNA integration sites in the Arabidopsis genome generated under non-selective conditions. Plant J 51:779\u2013791","journal-title":"Plant J"},{"key":"2431_CR26","unstructured":"Larralde C, Sciutto E (2006) El control de la Taenia solium en M\u00e9xico quinientos a\u00f1os despu\u00e9s de su llegada al Nuevo Mundo. Cisticercosis, gu\u00eda para profesionales de la salud. Secretar\u00eda de Salud, Fundaci\u00f3n Mexicana para la Salud, Instituto Nacional de Salud P\u00fablica, Fondo de Cultura Econ\u00f3mica 7:182\u2013237. ISBN 968-16- 8138-X"},{"key":"2431_CR27","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1017\/S003118200600179X","volume":"133","author":"MW Lightowlers","year":"2006","unstructured":"Lightowlers MW (2006) Cestode vaccines: origins, current status and future prospects. Parasitology 133:27\u201342","journal-title":"Parasitology"},{"key":"2431_CR28","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1023\/A:1022354322226","volume":"51","author":"E Marquet-Blouin","year":"2003","unstructured":"Marquet-Blouin E, Bouche FB, Steinmetz A, Muller CP (2003) Neutralizing immunogenicity of transgenic carrot (Daucus carota L.) derived measles virus hemagglutinin. Plant Mol Biol 51:459\u2013469","journal-title":"Plant Mol Biol"},{"key":"2431_CR29","first-page":"219","volume":"29","author":"MP Mojica-Henshaw","year":"2003","unstructured":"Mojica-Henshaw MP, Francisco AD, De Guzman F, Tigno XT (2003) Possible immunomodulatory actions of Carica papaya seed extract. Clin Hemorheol Microcirc 29:219\u2013229","journal-title":"Clin Hemorheol Microcirc"},{"key":"2431_CR30","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.virol.2005.08.009","volume":"342","author":"A Molina","year":"2005","unstructured":"Molina A, Veramendi J, Herv\u00e1s-Stubbs S (2005) Induction of neutralizing antibodies by a tobacco chloroplast-derived vaccine based on a B cell epitope from canine parvovirus. Virology 342:266\u2013275","journal-title":"Virology"},{"key":"2431_CR31","doi-asserted-by":"crossref","first-page":"502","DOI":"10.4269\/ajtmh.1993.49.502","volume":"49","author":"JL Molinari","year":"1993","unstructured":"Molinari JL, Soto R, Tato P, Rodriguez D, Retana A, Sepulveda J, Palet A (1993) Immunization against porcine cysticercosis in an endemic area in Mexico: a field and laboratory study. Am J Trop Med Hyg 49:502\u2013512","journal-title":"Am J Trop Med Hyg"},{"key":"2431_CR32","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0304-4017(96)01102-8","volume":"69","author":"JL Molinari","year":"1997","unstructured":"Molinari JL, Rodriguez D, Tato P, Soto R, Arechavaleta F, Solano S (1997) Field trial for reducing porcine Taenia solium cysticercosis in Mexico by systematic vaccination of pigs. Vet Parasitol 69:55\u201363","journal-title":"Vet Parasitol"},{"key":"2431_CR33","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1016\/j.vaccine.2008.03.042","volume":"26","author":"J Morales","year":"2008","unstructured":"Morales J, Mart\u00ednez JJ, Manoutcharian K, Hern\u00e1ndez M, Fleury A, Gevorkian G, Acero G, Blancas A, Toledo A, Cervantes J, Maza V, Quet F, Bonnabau H, De Aluja AS, Fragoso G, Larralde C, Sciutto E (2008) Inexpensive anti-cysticercosis vaccine: S3Pvac expressed in heat inactivated M13 filamentous phage proves effective against naturally acquired Taenia solium porcine cysticercosis. Vaccine 26:2899\u20132905","journal-title":"Vaccine"},{"key":"2431_CR34","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1399-3054.1962.tb08052.x","volume":"15","author":"T Murashige","year":"1962","unstructured":"Murashige T, Skoog F (1962) A revised medium for rapid growth and bioassays with tobacco tissue culture. Physiol Plant 15:473\u2013479","journal-title":"Physiol Plant"},{"key":"2431_CR35","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1007\/s00436-007-0853-8","volume":"102","author":"RM Parkhouse","year":"2008","unstructured":"Parkhouse RM, Bonay P, Gonz\u00e1lez LM, Ferrer E, G\u00e1rate T, Aguilar CM, Cortez AMM, Harrison LJ (2008) TSOL18\/HP6-Tsol, an immunogenic Taenia solium oncospheral adhesion protein and potential protective antigen. Parasitol Res 102:921\u2013926","journal-title":"Parasitol Res"},{"key":"2431_CR36","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1586\/14760584.2014.913483","volume":"13","author":"S Rosales-Mendoza","year":"2014","unstructured":"Rosales-Mendoza S, Salazar-Gonz\u00e1lez JA (2014) Immunological aspects of using plant cells as delivery vehicles for oral vaccines. Expert Rev Vaccines 13:737\u2013749","journal-title":"Expert Rev Vaccines"},{"key":"2431_CR37","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s12033-014-9837-y","volume":"57","author":"S Rosales-Mendoza","year":"2015","unstructured":"Rosales-Mendoza S, Tello-Olea MA (2015) Carrot cells: a pioneering platform for biopharmaceuticals production. Mol Biotechnol 57:219\u2013232","journal-title":"Mol Biotechnol"},{"key":"2431_CR38","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1007\/s00299-007-0310-2","volume":"26","author":"S Rosales-Mendoza","year":"2007","unstructured":"Rosales-Mendoza S, Soria-Guerra RE, de Jes\u00fas Olivera-Flores MT, L\u00f3pez-Revilla R, Arg\u00fcello-Astorga GR, Jim\u00e9nez-Bremont JF, Garc\u00eda-de la Cruz RF, Loyola-Rodr\u00edguez JP, Alpuche-Sol\u00eds AG (2007) Expression of Escherichia coli heat-labile enterotoxin b subunit (LTB) in carrot (Daucus carota L.). Plant Cell Rep 26:969\u2013976","journal-title":"Plant Cell Rep"},{"key":"2431_CR39","first-page":"79","volume":"1","author":"S Rosales-Mendoza","year":"2008","unstructured":"Rosales-Mendoza S, Soria-Guerra RE, L\u00f3pez-Revilla R, Moreno-Fierros L, Alpuche-Sol\u00eds AG (2008) Ingestion of transgenic carrots expressing the Escherichia coli heat-labile enterotoxin B subunit protects mice against cholera toxin challenge. Plant Cell Rep 1:79\u201384","journal-title":"Plant Cell Rep"},{"key":"2431_CR40","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.jplph.2010.06.012","volume":"168","author":"S Rosales-Mendoza","year":"2011","unstructured":"Rosales-Mendoza S, Soria-Guerra RE, Moreno-Fierros L, Han Y, Alpuche-Sol\u00eds AG, Korban SS (2011) Transgenic carrot tap roots expressing an immunogenic F1-V fusion protein from Yersinia pestis are immunogenic in mice. J Plant Physiol 168:174\u2013180","journal-title":"J Plant Physiol"},{"key":"2431_CR41","doi-asserted-by":"crossref","first-page":"516","DOI":"10.2307\/3284715","volume":"84","author":"G Rosas","year":"1998","unstructured":"Rosas G, Cruz-Revilla C, Fragoso G, L\u00f3pez-Casillas F, P\u00e9rez A, Bonilla MA, Rosales R, Sciutto E (1998) Taenia crassiceps cysticercosis: humoral immune response and protection elicited by DNA immunization. J Parasitol 84:516\u2013523","journal-title":"J Parasitol"},{"key":"2431_CR42","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1017\/S0031182006001132","volume":"134","author":"E Sciutto","year":"2007","unstructured":"Sciutto E, Morales J, Martinez JJ, Toledo A, Villalobos MN, Cruz-Revilla C, Meneses G, Hern\u00e1ndez M, Diaz A, Rodarte LF, Acero G, Gevorkian G, Manoutcharian K, Paniagua J, Fragoso G, Fleury A, Larralde R, De Aluja AS, Larralde C (2007) Further evaluation of the synthetic peptide vaccine S3Pvac against Taenia solium cysticercosis in pigs in an endemic town of Mexico. Parasitology 134:129\u2013133","journal-title":"Parasitology"},{"key":"2431_CR43","doi-asserted-by":"crossref","first-page":"415","DOI":"10.2174\/156802608783790839","volume":"8","author":"E Sciutto","year":"2008","unstructured":"Sciutto E, Fragoso G, de Aluja AS, Hern\u00e1ndez M, Rosas G, Larralde C (2008) Vaccines against cysticercosis. Curr Top Med Chem 8:415\u2013423","journal-title":"Curr Top Med Chem"},{"key":"2431_CR44","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1645\/GE-3101.1","volume":"99","author":"E Sciutto","year":"2013","unstructured":"Sciutto E, Fragoso G, Hern\u00e1ndez M, Rosas G, Martinez JJ, Fleury A, Cervantes J, Aluja A, Larralde C (2013) Development of the S3pvac vaccine against murine Taenia crassiceps cysticercosis: a historical review. J Parasitol 99:693\u2013702","journal-title":"J Parasitol"},{"key":"2431_CR45","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1586\/14760584.2.6.763","volume":"2","author":"SJ Streatfield","year":"2003","unstructured":"Streatfield SJ, Howard JA (2003) Plant production systems for vaccines. Expert Rev Vaccines 2:763\u2013775","journal-title":"Expert Rev Vaccines"},{"key":"2431_CR46","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.1128\/IAI.67.5.2522-2530.1999","volume":"67","author":"A Toledo","year":"1999","unstructured":"Toledo A, Larralde C, Fragoso G, Gevorkian G, Manoutcharian K, Hern\u00e1ndez M, Acero G, Rosas G, L\u00f3pez-Casillas F, Garfias CK, V\u00e1zquez R, Terrazas I, Sciutto E (1999) Towards a Taenia solium cysticercosis vaccine: an epitope shared by Taenia crassiceps and Taenia solium protects mice against experimental cysticercosis. Infect Immun 67:2522\u20132530","journal-title":"Infect Immun"},{"key":"2431_CR47","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1128\/IAI.69.3.1766-1773.2001","volume":"69","author":"A Toledo","year":"2001","unstructured":"Toledo A, Fragoso G, Rosas G, Hern\u00e1ndez M, Gevorkian G, L\u00f3pez-Casillas F, Hern\u00e1ndez B, Acero G, Huerta M, Larralde C, Sciutto E (2001) Two epitopes shared by Taenia crassiceps and Taenia solium confer protection against murine T. crassiceps cysticercosis along with a prominent T1 response. Infect Immun 69:1766\u20131773","journal-title":"Infect Immun"},{"key":"2431_CR48","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1016\/S0264-410X(02)00661-8","volume":"21","author":"QM Wang","year":"2003","unstructured":"Wang QM, Sun SH, Hu ZL, Wu D, Wang ZC (2003) Immune response and protection elicited by DNA immunization against Taenia cysticercosis. Vaccine 21:1672\u20131680","journal-title":"Vaccine"},{"key":"2431_CR49","doi-asserted-by":"crossref","first-page":"3538","DOI":"10.1016\/j.vaccine.2006.02.002","volume":"24","author":"DE Webster","year":"2006","unstructured":"Webster DE, Smith SD, Pickering RJ, Strugnell RA, Dry IB, Wesselingh SL (2006) Measles virus hemagglutinin protein expressed in transgenic lettuce induces neutralising antibodies in mice following mucosal vaccination. Vaccine 24:3538\u20133544","journal-title":"Vaccine"},{"key":"2431_CR50","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/BF02773139","volume":"22","author":"H Weng","year":"2004","unstructured":"Weng H, Pan A, Yang L, Zhang C, Liu Z, Zhang D (2004) Estimating number of transgene copies in transgenic rapeseed by real-time PCR assay with HMG I\/Y as an endogenous reference gene. Plant Mol Biol Rep 22:289\u2013300","journal-title":"Plant Mol Biol Rep"},{"key":"2431_CR51","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1166\/jnn.2005.221","volume":"5","author":"L Wu","year":"2005","unstructured":"Wu L, Diao Z, Dengm X, Gao J, Zhou Z, Liu Y, Wang Y (2005) DNA vaccine against Taenia solium cysticercosis expressed as a modified hepatitis B virus core particle containing three epitopes shared by Taenia crassiceps and Taenia solium. J Nanosci Nanotechnol 5:1204\u20131210","journal-title":"J Nanosci Nanotechnol"},{"key":"2431_CR52","doi-asserted-by":"crossref","first-page":"313","DOI":"10.4161\/hv.7.3.14207","volume":"7","author":"V Yusibov","year":"2011","unstructured":"Yusibov V, Streatfield SJ, Kushnir N (2011) Clinical development of plant-produced recombinant pharmaceuticals: vaccines, antibodies, and beyond. Hum Vaccin 7:313\u2013321","journal-title":"Hum Vaccin"}],"container-title":["Planta"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00425-015-2431-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00425-015-2431-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00425-015-2431-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T23:48:58Z","timestamp":1599868138000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00425-015-2431-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,27]]},"references-count":52,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["2431"],"URL":"https:\/\/doi.org\/10.1007\/s00425-015-2431-0","relation":{},"ISSN":["0032-0935","1432-2048"],"issn-type":[{"value":"0032-0935","type":"print"},{"value":"1432-2048","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,27]]}}}