{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T10:55:12Z","timestamp":1762340112112},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2006,11,8]],"date-time":"2006-11-08T00:00:00Z","timestamp":1162944000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Virchows Arch"],"published-print":{"date-parts":[[2006,11,23]]},"DOI":"10.1007\/s00428-006-0288-0","type":"journal-article","created":{"date-parts":[[2006,11,7]],"date-time":"2006-11-07T10:03:14Z","timestamp":1162893794000},"page":"667-672","source":"Crossref","is-referenced-by-count":18,"title":["Expression of p16 in sinonasal malignant melanoma"],"prefix":"10.1007","volume":"449","author":[{"given":"Alessandro","family":"Franchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Llucia","family":"Alos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Gale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Massi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milena","family":"Paglierani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Santucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Zidar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Cardesa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2006,11,8]]},"reference":[{"key":"288_CR1","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1002\/hed.2890040509","volume":"4","author":"JG Batsakis","year":"1982","unstructured":"Batsakis JG, Regezi JA, Solomon AR, Rice DH (1982) The pathology of head and neck tumors: mucosal melanomas. Head Neck Surg 4:404\u2013418","journal-title":"Head Neck Surg"},{"key":"288_CR2","first-page":"1424","volume":"44","author":"JG Batsakis","year":"1994","unstructured":"Batsakis JG, Cove H (1994) Melanosis, melanocytic hyperplasia, and primary malignant melanoma of the nasal cavity. Cancer 44:1424\u20131433","journal-title":"Cancer"},{"key":"288_CR3","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1002\/1097-0142(19840901)54:5<907::AID-CNCR2820540526>3.0.CO;2-Z","volume":"54","author":"A Berthelsen","year":"1984","unstructured":"Berthelsen A, Andersen AP, Jensen S, Hansen HA (1984) Melanomas of the mucosa in the oral cavity and the upper respiratory passages. Cancer 54:907\u2013912","journal-title":"Cancer"},{"key":"288_CR4","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1002\/(SICI)1097-0142(19981015)83:8<1664::AID-CNCR23>3.0.CO;2-G","volume":"83","author":"AE Chang","year":"1998","unstructured":"Chang AE, Karnell LH, Menck HR (1998) The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer 83:1664\u20131678","journal-title":"Cancer"},{"key":"288_CR5","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1056\/NEJMoa050092","volume":"353","author":"JA Curtin","year":"2005","unstructured":"Curtin JA, Fridlyand J, Kageshita T, Patel HN, Busam KJ, Kutzner H, Cho KH, Aiba S, Brocker EB, LeBoit PE, Pinkel D, Bastian BC (2005) Distinct sets of genetic alterations in melanoma. N Engl J Med 353:2135\u20132147","journal-title":"N Engl J Med"},{"key":"288_CR6","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1093\/ajcp\/96.6.689","volume":"96","author":"DW Franquemont","year":"1991","unstructured":"Franquemont DW, Mills SE (1991) Sinonasal malignant melanoma. A clinicopathologic and immunohistochemical study of 14 cases. Am J Clin Pathol 96:689\u2013697","journal-title":"Am J Clin Pathol"},{"key":"288_CR7","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1001\/archotol.1973.00780010332008","volume":"97","author":"HM Freedman","year":"1973","unstructured":"Freedman HM, DeSanto LW, Devine KD, Weiland LH (1973) Malignant melanoma of the nasal cavity and paranasal sinuses. Arch Otolaryngol 97:322\u2013325","journal-title":"Arch Otolaryngol"},{"key":"288_CR8","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/00008390-200202000-00011","volume":"12","author":"GF Hofbauer","year":"2002","unstructured":"Hofbauer GF, Boni R, Simmen D, Mihic D, Nestle FO, Burg G, Dummer R (2002) Histological, immunological and molecular features of a nasal mucosa primary melanoma associated with nasal melanosis. Melanoma Res 12:77\u201382","journal-title":"Melanoma Res"},{"key":"288_CR9","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1126\/science.8153634","volume":"264","author":"A Kamb","year":"1994","unstructured":"Kamb A, Gruis NA, Weaver-Feldhaus J, Liu Q, Harshman K, Tavtigian SV, Stockert E, Day RS III, Johnson BE, Skolnick MH (1994) A cell cycle regulator potentially involved in genesis of many tumor types. Science 264:436\u2013440","journal-title":"Science"},{"key":"288_CR10","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1017\/S0022215100092586","volume":"96","author":"V Lund","year":"1982","unstructured":"Lund V (1982) Malignant melanoma of the nasal cavity and paranasal sinuses. J Laryngol Otol 96:347\u2013355","journal-title":"J Laryngol Otol"},{"key":"288_CR11","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1002\/ijc.21608","volume":"118","author":"D Mihic-Probst","year":"2006","unstructured":"Mihic-Probst D, Mnich CD, Oberholzer PA, Seifert B, Sasse B, Moch H, Dummer R (2006). p16 expression in primary malignant melanoma is associated with prognosis and lymph node status. Int J Cancer 118:2262\u20132268","journal-title":"Int J Cancer"},{"key":"288_CR12","first-page":"303","volume":"28","author":"M Padilla Parrado","year":"2001","unstructured":"Padilla Parrado M, Saez Castillo AI, Galan Morales JT, Orradre Romeo JL, Delgado Quero AL, Sanchez Carrion S (2001) Melanoma maligno de fosas nasales. Estudio retrospectivo. Analisis de la expresion de p53 y p16INK4. An Otorrinolaringol Ibero Am 28:303\u2013316","journal-title":"An Otorrinolaringol Ibero Am"},{"key":"288_CR13","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/(SICI)1097-0215(19970220)74:1<26::AID-IJC5>3.0.CO;2-2","volume":"74","author":"S Piccinin","year":"1997","unstructured":"Piccinin S, Doglioni C, Maestro R, Vukosavljevic T, Gasparotto D, D\u2019Orazi C, Boiocchi M (1997) p16\/CDKN2 and CDK4 gene mutations in sporadic melanoma development and progression. Int J Cancer 74:26\u201330","journal-title":"Int J Cancer"},{"key":"288_CR14","first-page":"2713","volume":"55","author":"JA Reed","year":"1995","unstructured":"Reed JA, Loganzo F Jr, Shea CR, Walker GJ, Flores JF, Glendening JM, Bogdany JK, Shiel MJ, Haluska FG, Fountain JW et al (1995) Loss of expression of the p16\/cyclin-dependent kinase inhibitor 2 tumor suppressor gene in melanocytic lesions correlates with invasive stage of tumor progression. Cancer Res 55:2713\u20132718","journal-title":"Cancer Res"},{"key":"288_CR15","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/366704a0","volume":"366","author":"M Serrano","year":"1993","unstructured":"Serrano M, Hannon GJ, Beach D (1993) A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D\/CDK4. Nature 366:704\u2013707","journal-title":"Nature"},{"key":"288_CR16","doi-asserted-by":"crossref","first-page":"3092","DOI":"10.1038\/sj.onc.1206461","volume":"22","author":"NE Sharpless","year":"2003","unstructured":"Sharpless NE, Chin L (2003) The INK4a\/ARF locus and melanoma. Oncogene 22:3092\u20133098","journal-title":"Oncogene"},{"key":"288_CR17","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/00000372-199806000-00006","volume":"20","author":"LE Sparrow","year":"1998","unstructured":"Sparrow LE, Eldon MJ, English DR, Heenan PJ (1998) p16 and p21WAF1 protein expression in melanocytic tumors by immunohistochemistry. Am J Dermatopathol 20:255\u2013261","journal-title":"Am J Dermatopathol"},{"key":"288_CR18","first-page":"1845","volume":"6","author":"O Straume","year":"2000","unstructured":"Straume O, Sviland L, Akslen LA (2000). Loss of nuclear p16 protein expression correlates with increased tumor cell proliferation (Ki-67) and poor prognosis in patients with vertical growth phase melanoma. Clin Cancer Res 6:1845\u20131853","journal-title":"Clin Cancer Res"},{"key":"288_CR19","first-page":"1086","volume":"113","author":"TK Trapp","year":"1987","unstructured":"Trapp TK, Fu YS, Calcaterra TC (1987) Melanoma of the nasal and paranasal sinus mucosa. Head Neck Surg 113:1086\u20131089","journal-title":"Head Neck Surg"},{"key":"288_CR20","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1097\/00000478-200305000-00004","volume":"27","author":"LD Thompson","year":"2003","unstructured":"Thompson LD, Wieneke JA, Miettinen M (2003) Sinonasal tract and nasopharyngeal melanomas: a clinicopathologic study of 115 cases with a proposed staging system. Am J Surg Pathol 27:594\u2013611","journal-title":"Am J Surg Pathol"},{"key":"288_CR21","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/gcc.10156","volume":"36","author":"M Dijk van","year":"2003","unstructured":"van Dijk M, Sprenger S, Rombout P, Marres H, Kaanders J, Jeuken J, Ruiter D (2003) Distinct chromosomal aberrations in sinonasal mucosal melanoma as detected by comparative genomic hybridization. Genes Chromosomes Cancer 36:151\u2013158","journal-title":"Genes Chromosomes Cancer"},{"key":"288_CR22","first-page":"65","volume-title":"World Health Organization classification of tumours. Pathology and genetics of head and neck tumours","author":"BM Wenig","year":"2005","unstructured":"Wenig BM, Dulguerov P, Kapadia SB, Prasad ML, Fanburg Smith JC, Thompson LDR (2005) Neuroectodermal tumours. In: Barnes L, Eveson JW, Reichart P, Sidranski D (eds) World Health Organization classification of tumours. Pathology and genetics of head and neck tumours. IARC Press, Lyon, pp 65\u201375"}],"container-title":["Virchows Archiv"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-006-0288-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00428-006-0288-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-006-0288-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T21:33:58Z","timestamp":1559079238000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00428-006-0288-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11,8]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,11,23]]}},"alternative-id":["288"],"URL":"https:\/\/doi.org\/10.1007\/s00428-006-0288-0","relation":{},"ISSN":["0945-6317","1432-2307"],"issn-type":[{"value":"0945-6317","type":"print"},{"value":"1432-2307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,11,8]]}}}