{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:50:10Z","timestamp":1782604210909,"version":"3.54.5"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2007,3,13]],"date-time":"2007-03-13T00:00:00Z","timestamp":1173744000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"},{"start":{"date-parts":[[2007,3,13]],"date-time":"2007-03-13T00:00:00Z","timestamp":1173744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virchows Arch"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1007\/s00428-007-0384-9","type":"journal-article","created":{"date-parts":[[2007,3,12]],"date-time":"2007-03-12T11:03:47Z","timestamp":1173697427000},"page":"493-502","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Frequency and diagnostic patterns of lymphomas in liver biopsies with respect to the WHO classification"],"prefix":"10.1007","volume":"450","author":[{"given":"Christoph","family":"Loddenkemper","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Longerich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Hummel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Ernestus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Anagnostopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Peter","family":"Dienes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Schirmacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Stein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,3,13]]},"reference":[{"key":"384_CR1","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1038\/35000501","volume":"403","author":"AA Alizadeh","year":"2000","unstructured":"Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A, Boldrick JC, Sabet H, Tran T, Yu X, Powell JI, Yang L, Marti GE, Moore T, Hudson J Jr, Lu L, Lewis DB, Tibshirani R, Sherlock G, Chan WC, Greiner TC, Weisenburger DD, Armitage JO, Warnke R, Levy R, Wilson W, Grever MR, Byrd JC, Botstein D, Brown PO, Staudt LM (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403:503\u2013511","journal-title":"Nature"},{"key":"384_CR2","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1093\/ajcp\/109.5.600","volume":"109","author":"V Ascoli","year":"1998","unstructured":"Ascoli V, Lo Coco F, Artini M, Levrero M, Martelli M, Negro F (1998) Extranodal lymphomas associated with hepatitis C virus infection. Am J Clin Pathol 109:600\u2013609","journal-title":"Am J Clin Pathol"},{"key":"384_CR3","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1053\/jhep.2003.50121","volume":"37","author":"JP Bronowicki","year":"2003","unstructured":"Bronowicki JP, Bineau C, Feugier P, Hermine O, Brousse N, Oberti F, Rousselet MC, Dharancy S, Gaulard P, Flejou JF, Cazals-Hatem D, Labouyrie E (2003) Primary lymphoma of the liver: clinical-pathological features and relationship with HCV infection in French patients. Hepatology 37:781\u2013787","journal-title":"Hepatology"},{"key":"384_CR4","first-page":"165","volume":"113","author":"BF Burns","year":"1983","unstructured":"Burns BF, Warnke RA, Doggett RS, Rouse RV (1983) Expression of a T-cell antigen (Leu-1) by B-cell lymphomas. Am J Pathol 113:165\u2013171","journal-title":"Am J Pathol"},{"key":"384_CR5","first-page":"553","volume":"110","author":"D Caccamo","year":"1986","unstructured":"Caccamo D, Pervez NK, Marchevsky A (1986) Primary lymphoma of the liver in the acquired immunodeficiency syndrome. Arch Pathol Lab Med 110:553\u2013555","journal-title":"Arch Pathol Lab Med"},{"key":"384_CR6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1177\/32.2.6198355","volume":"32","author":"JL Cordell","year":"1984","unstructured":"Cordell JL, Falini B, Erber WN, Ghosh AK, Abdulaziz Z, MacDonald S, Pulford KA, Stein H, Mason DY (1984) Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 32:219\u2013229","journal-title":"J Histochem Cytochem"},{"key":"384_CR7","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3109\/10428199809057606","volume":"31","author":"F Dammacco","year":"1998","unstructured":"Dammacco F, Gatti P, Sansonno D (1998) Hepatitis C virus infection, mixed cryoglobulinemia, and non-Hodgkin\u2019s lymphoma: an emerging picture. Leuk Lymphoma 31:463\u2013476","journal-title":"Leuk Lymphoma"},{"key":"384_CR8","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/S1092-9134(98)80039-7","volume":"2","author":"JL Dargent","year":"1998","unstructured":"Dargent JL, De Wolf-Peeters C (1998) Liver involvement by lymphoma: identification of a distinctive pattern of infiltration related to T-cell\/histiocyte-rich B-cell lymphoma. Ann Diagn Pathol 2:363\u2013369","journal-title":"Ann Diagn Pathol"},{"key":"384_CR9","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1002\/(SICI)1096-9896(199906)188:2<146::AID-PATH334>3.0.CO;2-7","volume":"188","author":"E Dippel","year":"1999","unstructured":"Dippel E, Assaf C, Hummel M, Schrag HJ, Stein H, Goerdt S, Orfanos CE (1999) Clonal T-cell receptor gamma-chain gene rearrangement by PCR-based GeneScan analysis in advanced cutaneous T-cell lymphoma: a critical evaluation. J Pathol 188:146\u2013154","journal-title":"J Pathol"},{"key":"384_CR10","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1097\/00000478-200307000-00005","volume":"27","author":"A Dogan","year":"2003","unstructured":"Dogan A, Burke JS, Goteri G, Stitson RN, Wotherspoon AC, Isaacson PG (2003) Micronodular T-cell\/histiocyte-rich large B-cell lymphoma of the spleen: histology, immunophenotype, and differential diagnosis. Am J Surg Pathol 27:903\u2013911","journal-title":"Am J Surg Pathol"},{"key":"384_CR11","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1182\/blood-2003-05-1545","volume":"103","author":"CP Hans","year":"2004","unstructured":"Hans CP, Weisenburger DD, Greiner TC, Gascoyne RD, Delabie J, Ott G, Muller-Hermelink HK, Campo E, Braziel RM, Jaffe ES, Pan Z, Farinha P, Smith LM, Falini B, Banham AH, Rosenwald A, Staudt LM, Connors JM, Armitage JO, Chan WC (2004) Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray. Blood 103:275\u2013282","journal-title":"Blood"},{"key":"384_CR12","doi-asserted-by":"publisher","first-page":"2011","DOI":"10.1002\/(SICI)1097-0142(19961101)78:9<2011::AID-CNCR24>3.0.CO;2-Z","volume":"78","author":"AC Harris","year":"1996","unstructured":"Harris AC, Ben-Ezra JM, Contos MJ, Kornstein MJ (1996) Malignant lymphoma can present as hepatobiliary disease. Cancer 78:2011\u20132019","journal-title":"Cancer"},{"key":"384_CR13","doi-asserted-by":"publisher","first-page":"2639","DOI":"10.1002\/1097-0142(19930415)71:8<2639::AID-CNCR2820710832>3.0.CO;2-Q","volume":"71","author":"AC Harris","year":"1993","unstructured":"Harris AC, Kornstein MJ (1993) Malignant lymphoma imitating hepatitis. Cancer 71:2639\u20132646","journal-title":"Cancer"},{"key":"384_CR14","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1093\/ajcp\/75.6.816","volume":"75","author":"SM Hsu","year":"1981","unstructured":"Hsu SM, Raine L, Fanger H (1981) The use of antiavidin antibody and avidin\u2013biotin\u2013peroxidase complex in immunoperoxidase technics. Am J Clin Pathol 75:816\u2013821","journal-title":"Am J Clin Pathol"},{"key":"384_CR15","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1055\/s-2008-1040581","volume":"7","author":"ES Jaffe","year":"1987","unstructured":"Jaffe ES (1987) Malignant lymphomas: pathology of hepatic involvement. Semin Liver Dis 7:257\u2013268","journal-title":"Semin Liver Dis"},{"key":"384_CR16","volume-title":"World Health Organisation of Tumours. Pathology World Health Organisation of Tumours. Pathology and genetics of tumours of haematopoietic and lymphoid tissues","year":"2001","unstructured":"Jaffe ES, Harris NL, Stein H, Vardiman JW (eds) (2001) World Health Organisation of Tumours. Pathology World Health Organisation of Tumours. Pathology and genetics of tumours of haematopoietic and lymphoid tissues. IARC, Lyon"},{"key":"384_CR17","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1111\/j.1365-2559.1993.tb01193.x","volume":"23","author":"SM Khan","year":"1993","unstructured":"Khan SM, Cottrell BJ, Millward-Sadler GH, Wright DH (1993) T-cell-rich B-cell lymphoma presenting as liver disease. Histopathology 23:217\u2013224","journal-title":"Histopathology"},{"key":"384_CR18","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1002\/1097-0142(197403)33:3<657::AID-CNCR2820330311>3.0.CO;2-D","volume":"33","author":"H Kim","year":"1974","unstructured":"Kim H, Dorfman RF (1974) Morphological studies of 84 untreated patients subjected to laparotomy for the staging of non-Hodgkin\u2019s lymphomas. Cancer 33:657\u2013674","journal-title":"Cancer"},{"key":"384_CR19","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1309\/RM1Q-1T0B-WKQB-AF5A","volume":"114","author":"SH Kroft","year":"2000","unstructured":"Kroft SH, Howard MS, Picker LJ, Ansari MQ, Aquino DB, McKenna RW (2000) De novo CD5+diffuse large B-cell lymphomas. A heterogeneous group containing an unusual form of splenic lymphoma. Am J Clin Pathol 114:523\u2013533","journal-title":"Am J Clin Pathol"},{"key":"384_CR20","doi-asserted-by":"publisher","first-page":"2301","DOI":"10.1111\/j.1572-0241.1998.00648.x","volume":"93","author":"S Matano","year":"1998","unstructured":"Matano S, Nakamura S, Annen Y, Hattori N, Kiyohara K, Kakuta K, Kyoda K, Sugimoto T (1998) Primary hepatic lymphoma in a patient with chronic hepatitis B. Am J Gastroenterol 93:2301\u20132302","journal-title":"Am J Gastroenterol"},{"key":"384_CR21","doi-asserted-by":"publisher","first-page":"2241","DOI":"10.1023\/A:1018858415936","volume":"42","author":"M Mohler","year":"1997","unstructured":"Mohler M, Gutzler F, Kallinowski B, Goeser T, Stremmel W (1997) Primary hepatic high-grade non-Hodgkin\u2019s lymphoma and chronic hepatitis C infection. Dig Dis Sci 42:2241\u20132245","journal-title":"Dig Dis Sci"},{"key":"384_CR22","first-page":"215","volume":"44","author":"S Ozaki","year":"1998","unstructured":"Ozaki S, Ogasahara K, Kosaka M, Inoshita T, Wakatsuki S, Uehara H, Matsumoto T (1998) Hepatosplenic gamma delta T-cell lymphoma associated with hepatitis B virus infection. J Med Investig 44:215\u2013217","journal-title":"J Med Investig"},{"key":"384_CR23","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1111\/j.1600-0609.2005.00429.x","volume":"74","author":"CB Poulsen","year":"2005","unstructured":"Poulsen CB, Borup R, Nielsen FC, Borregaard N, Hansen M, Gronbaek K, Moller MB, Ralfkiaer E (2005) Microarray-based classification of diffuse large B-cell lymphoma. Eur J Haematol 74:453\u2013465","journal-title":"Eur J Haematol"},{"key":"384_CR24","first-page":"404","volume":"11","author":"RM Prabhu","year":"1998","unstructured":"Prabhu RM, Medeiros LJ, Kumar D, Drachenberg CI, Papadimitriou JC, Appelman HD, Johnson LB, Laurin J, Heyman M, Abruzzo LV (1998) Primary hepatic low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) associated with primary biliary cirrhosis. Mod Pathol 11:404\u2013410","journal-title":"Mod Pathol"},{"key":"384_CR25","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1097\/00000478-199909000-00017","volume":"23","author":"L Rubbia-Brandt","year":"1999","unstructured":"Rubbia-Brandt L, Brundler MA, Kerl K, Negro F, Nador RG, Scherrer A, Kurt AM, Mentha G, Borisch B (1999) Primary hepatic diffuse large B-cell lymphoma in a patient with chronic hepatitis C. Am J Surg Pathol 23:1124\u20131130","journal-title":"Am J Surg Pathol"},{"key":"384_CR26","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1111\/j.1365-2559.1995.tb00192.x","volume":"26","author":"IB Scheimberg","year":"1995","unstructured":"Scheimberg IB, Pollock DJ, Collins PW, Doran HM, Newland AC, van der Walt JD (1995) Pathology of the liver in leukaemia and lymphoma. A study of 110 autopsies. Histopathology 26:311\u2013321","journal-title":"Histopathology"},{"key":"384_CR27","doi-asserted-by":"publisher","first-page":"2257","DOI":"10.1038\/sj.leu.2403202","volume":"17","author":"JJ van Dongen","year":"2003","unstructured":"van Dongen JJ, Langerak AW, Bruggemann M, Evans PA, Hummel M, Lavender FL, Delabesse E, Davi F, Schuuring E, Garcia-Sanz R, van Krieken JH, Droese J, Gonzalez D, Bastard C, White HE, Spaargaren M, Gonzalez M, Parreira A, Smith JL, Morgan GJ, Kneba M, Macintyre EA (2003) Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 17:2257\u20132317","journal-title":"Leukemia"},{"key":"384_CR28","first-page":"343","volume":"13","author":"JJ Voigt","year":"1989","unstructured":"Voigt JJ, Vinel JP, Caveriviere P, Pradere B, Chittal S, al Saati T, Cales P, Delsol G. (1989) [Immunochemical diagnosis of hepatic localizations in malignant lymphoid hematologic diseases. Study of 80 cases]. Gastroenterol Clin Biol 13:343\u2013352","journal-title":"Gastroenterol Clin Biol"},{"key":"384_CR29","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S0344-0338(98)80068-X","volume":"194","author":"R Walz-Mattmuller","year":"1998","unstructured":"Walz-Mattmuller R, Horny HP, Ruck P, Kaiserling E (1998) Incidence and pattern of liver involvement in haematological malignancies. Pathol Res Pract 194:781\u2013789","journal-title":"Pathol Res Pract"},{"key":"384_CR30","first-page":"47","volume":"22","author":"MJ Wick","year":"2002","unstructured":"Wick MJ, Leithauser F, Reimann J (2002) The hepatic immune system. Crit Rev Immunol 22:47\u2013103","journal-title":"Crit Rev Immunol"},{"key":"384_CR31","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1182\/blood.V99.3.815","volume":"99","author":"M Yamaguchi","year":"2002","unstructured":"Yamaguchi M, Seto M, Okamoto M, Ichinohasama R, Nakamura N, Yoshino T, Suzumiya J, Murase T, Miura I, Akasaka T, Tamaru J, Suzuki R, Kagami Y, Hirano M, Morishima Y, Ueda R, Shiku H, Nakamura S (2002) De novo CD5+ diffuse large B-cell lymphoma: a clinicopathologic study of 109 patients. Blood 99:815\u2013821","journal-title":"Blood"}],"container-title":["Virchows Archiv"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-007-0384-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00428-007-0384-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-007-0384-9.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-007-0384-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T17:29:56Z","timestamp":1630430996000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00428-007-0384-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3,13]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["384"],"URL":"https:\/\/doi.org\/10.1007\/s00428-007-0384-9","relation":{},"ISSN":["0945-6317","1432-2307"],"issn-type":[{"value":"0945-6317","type":"print"},{"value":"1432-2307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,3,13]]},"assertion":[{"value":"3 November 2006","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2006","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 December 2006","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 March 2007","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}