{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:43:01Z","timestamp":1788406981444,"version":"build-2803163510"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2008,8,8]],"date-time":"2008-08-08T00:00:00Z","timestamp":1218153600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Virchows Arch"],"published-print":{"date-parts":[[2008,10]]},"DOI":"10.1007\/s00428-008-0647-0","type":"journal-article","created":{"date-parts":[[2008,8,7]],"date-time":"2008-08-07T05:57:45Z","timestamp":1218088665000},"page":"321-328","source":"Crossref","is-referenced-by-count":11,"title":["What is the significance of CD34 immunostaining in the extraglomerular and intraglomerular mesangium?"],"prefix":"10.1007","volume":"453","author":[{"given":"Cristina","family":"Gluhovschi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gheorghe","family":"Gluhovschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Potencz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Herman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ligia","family":"Petrica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Velciov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gheorghe","family":"Bozdog","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flaviu","family":"Bob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corina","family":"Vernic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Cioca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,8,8]]},"reference":[{"issue":"7","key":"647_CR1","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/j.1440-1681.1997.tb01240.x","volume":"24","author":"MS Goligorsky","year":"1997","unstructured":"Goligorsky MS, Iijima K, Krivenko Y et al (1997) Role of mesangial cells in macula densa to afferent arteriole information transfer. Clin Exp Pharmacol Physiol 24(7):527\u2013531","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"647_CR2","first-page":"974","volume-title":"Leucocyte typing VI. White cell differentiation antigens. Proceedings of the 6th International Workshop and Conference; 1996 Nov 10\u201314; Kobe, Japan","author":"H Nishio","year":"1997","unstructured":"Nishio H, Tada J, Hashiyama M et al (1997) MC7. CD34 workshop panel report. In: Kishimoto T, Kitukani H, von dem Borne AEG et al (eds) Leucocyte typing VI. White cell differentiation antigens. Proceedings of the 6th International Workshop and Conference; 1996 Nov 10\u201314; Kobe, Japan. Garland Publishing Inc, New York, pp 974\u2013976"},{"key":"647_CR3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1182\/blood.V87.1.1.1","volume":"87","author":"DS Krause","year":"1996","unstructured":"Krause DS, Fackler MJ, Civin CI et al (1996) CD34: structure, biology and clinical utility (Review). Blood; 87:1\u201313","journal-title":"Blood;"},{"issue":"1","key":"647_CR4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/(SICI)1096-9896(199909)189:1<105::AID-PATH388>3.0.CO;2-0","volume":"189","author":"K Naruse","year":"1999","unstructured":"Naruse K, Fujieda M, Hayashi Y et al (1999) CD34 expression as a novel marker of transformed mesangial cells in biopsied glomerular diseases. J Pathology 189(1):105\u2013111","journal-title":"J Pathology"},{"issue":"6","key":"647_CR5","first-page":"27","volume":"74","author":"NV Chebotareva","year":"2002","unstructured":"Chebotareva NV, Proppe D, Rudolf P et al (2002) Clinical significance of expression of the smooth muscle-actin alpha and CD34 antigen in mesangial cells in glomerulonephritis (Article in Russian). Ter Arkh 74(6):27\u201331","journal-title":"Ter Arkh"},{"key":"647_CR6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0002-9440(10)64701-3","volume":"156","author":"Y Natkunam","year":"2000","unstructured":"Natkunam Y, Rouse R, Zhu S et al (2000) Immunoblot analysis of CD34 expression in histologically diverse neoplasms. Am J Pathol 156:21\u201327","journal-title":"Am J Pathol"},{"issue":"7","key":"647_CR7","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1681\/ASN.V1271401","volume":"12","author":"T Imasawa","year":"2001","unstructured":"Imasawa T, Utsunomiya Y, Kawamura T et al (2001) The potential of bone marrow-derived cells to differentiate into glomerular mesangial cells. J Am Soc Nephrol 12(7):1401\u20131409","journal-title":"J Am Soc Nephrol"},{"issue":"3","key":"647_CR8","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1084\/jem.179.3.1053","volume":"179","author":"M Nishimura","year":"1994","unstructured":"Nishimura M, Toki J, Sugiura K et al (1994) Focal segmental glomerular sclerosis, a type of intractable chronic glomerulonephritis, is a stem cell disorder? J Exp Med 179(3):1053\u20131058","journal-title":"J Exp Med"},{"issue":"11","key":"647_CR9","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1172\/JCI200112916","volume":"108","author":"F Cornacchia","year":"2001","unstructured":"Cornacchia F, Fornoni A, Plati AR et al (2001) Glomerulosclerosis is transmitted by bone marrow-derived mesangial cell progenitors. J Clin Invest 108(11):1649\u20131656","journal-title":"J Clin Invest"},{"key":"647_CR10","unstructured":"Striker GE (2002) BM-derived progenitors deliver both their genotype and phenotype. Syllabus. ASN Renal Week; PGE Course: Advances in Cell and Molecular Biology: Integration with Renal Medicine. October 30\u201331, Philadelphia, Pennsylvania"},{"issue":"1","key":"647_CR11","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1093\/ndt\/gfh563","volume":"20","author":"I Neumann","year":"2005","unstructured":"Neumann I, Kain R, Regele H et al (2005) Histological and clinical predictors of early and late renal outcome in ANCA-associated vasculitis. Nephrol Dial Transpl 20(1):96\u2013104","journal-title":"Nephrol Dial Transpl"},{"key":"647_CR12","first-page":"169","volume-title":"Oxford textbook of clinical nephrology","year":"2005","unstructured":"Davison A, Cameron JS, Grunfeld JP et al (eds) (2005) Oxford textbook of clinical nephrology. 3rd edn. Oxford University Press, Oxford, pp 169\u2013182","edition":"3"},{"key":"647_CR13","first-page":"48","volume-title":"Basic and clinical biostatistics","author":"B Dawson","year":"2004","unstructured":"Dawson B, Trapp RG (2004) Basic and clinical biostatistics. Lange, New York, p 48"},{"issue":"4","key":"647_CR14","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1172\/JCI119592","volume":"100","author":"C Hugo","year":"1997","unstructured":"Hugo C, Shankland SJ, Bowen-Pope DF et al (1997) Extraglomerular origin of the mesangial cell after injury. J Clin Invest 100(4):786\u2013794","journal-title":"J Clin Invest"},{"key":"647_CR15","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1046\/j.1523-1755.1999.00641.x","volume":"56","author":"LA Haseley","year":"1999","unstructured":"Haseley LA, Hugo C, Reidy MA et al (1999) Dissociation of mesangial cell migration and proliferation in experimental glomerulonephritis. Kidney Int 56:964\u2013972","journal-title":"Kidney Int"},{"issue":"Suppl 1","key":"647_CR16","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1097\/01.ASN.0000068162.02174.29","volume":"14","author":"R Poulsom","year":"2003","unstructured":"Poulsom R, Alison MR, Cook T et al (2003) Bone marrow stem cells contribute to healing of the kidney. J Am Soc Nephrol 14(Suppl 1):S48\u2013S54","journal-title":"J Am Soc Nephrol"},{"key":"647_CR17","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1097\/01.ASN.0000061595.28546.A0","volume":"14","author":"F Lin","year":"2003","unstructured":"Lin F, Cordes K, Li L et al (2003) Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice. J Am Soc Nephrol 14:1188\u20131199","journal-title":"J Am Soc Nephrol"},{"key":"647_CR18","doi-asserted-by":"crossref","first-page":"3290","DOI":"10.1097\/01.ASN.0000098682.51956.06","volume":"14","author":"F Lin","year":"2003","unstructured":"Lin F, Igarashi P (2003) Searching for stem\/progenitor cells in the adult mouse kidney. J Am Soc Nephrol 14:3290\u20133292","journal-title":"J Am Soc Nephrol"},{"issue":"Suppl 7","key":"647_CR19","first-page":"S1","volume":"16","author":"FP Schena","year":"2003","unstructured":"Schena FP, Abbattista MR (2003) Stem cells: reparative medicine and nephrology (review). J Nephrol 16(Suppl 7):S1\u2013S5","journal-title":"J Nephrol"},{"issue":"3","key":"647_CR20","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1440-1797.2005.00373.x","volume":"10","author":"SD Ricardo","year":"2005","unstructured":"Ricardo SD, Deane JA (2005) Adult stem cells in renal injury and repair (review). Nephrology 10(3):276\u2013282","journal-title":"Nephrology"},{"issue":"4","key":"647_CR21","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1093\/ndt\/gfg028","volume":"18","author":"T Ito","year":"2003","unstructured":"Ito T (2003) Stem cells of the adult kidney:where are you from? Nephrol Dial Transplant 18(4):641\u2013644","journal-title":"Nephrol Dial Transplant"},{"key":"647_CR22","unstructured":"Julian B (2005) IgA Nephropathy. An update on pathogenesis. In: Clinical Nephrology Conferences. ASN Renal Week Philadelphia. Syllabus, pp 477\u2013490"},{"issue":"Suppl 1","key":"647_CR23","first-page":"9","volume":"17","author":"N Baddour","year":"2002","unstructured":"Baddour N, Adam AG, El Koraie AH et al (2002) The reparative role of stem cells in human glomerulonephritis. XXXIX Congress of the European Renal Association European Dialysis and Transplant Association July 14\u201317, 2002 Copenhagen Denmark. Nephrol Dial Transplant 17(Suppl 1):9\u201310 Abstracts","journal-title":"Nephrol Dial Transplant"},{"key":"647_CR24","unstructured":"Guo J, Schedl A, Krause DS (2004) Bone marrow transplantation attenuates progression of mesangial sclerosis in mouse. In ASN Congress, October 27\u2013November 1, 2004, St. Louis, MO SA FC 098 J Am Soc Nephrol Abstracts Issue"},{"issue":"1","key":"647_CR25","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1046\/j.1523-1755.2003.00046.x","volume":"64","author":"T Yokoo","year":"2003","unstructured":"Yokoo T, Ohoshi Y, Utsunomiya Y et al (2003) Gene delivery using human cord blood-derived CD34+ cells into inflamed glomeruli in NOD\/SCID mice. Kydney Int 64(1):102\u2013109","journal-title":"Kydney Int"},{"issue":"2","key":"647_CR26","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/sj.ki.5001559","volume":"70","author":"MS Goligorsky","year":"2006","unstructured":"Goligorsky MS, Rabelink T (2006) Meeting report: ISN forefronts in nephrology on endothelial biology and renal disease: from bench to prevention (review). Kidney Int 70(2):258\u2013264","journal-title":"Kidney Int"},{"key":"647_CR27","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1681\/ASN.V133806","volume":"13","author":"DH Kang","year":"2002","unstructured":"Kang DH, Kanellis J, Hugo C et al (2002) Role of the microvascular endothelium in progressive renal disease. J Am Soc Nephrol 13:806\u2013816","journal-title":"J Am Soc Nephrol"},{"key":"647_CR28","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1159\/000020540","volume":"6","author":"H Kitamura","year":"1998","unstructured":"Kitamura H, Shimizu A, Masuda Y et al (1998) Apoptosis in glomerular endothelial cells during the development of glomerulosclerosis in a remnant kidney model. Exp Nephrol 6:328\u2013336","journal-title":"Exp Nephrol"},{"key":"647_CR29","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1681\/ASN.V11147","volume":"11","author":"R Ohashi","year":"2000","unstructured":"Ohashi R, Kitamura H, Yamanaka N (2000) Peritubular capillary injury during the progression of experimental glomerulonephritis in rats. J Am Soc Nephrol 11:47\u201356","journal-title":"J Am Soc Nephrol"},{"key":"647_CR30","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1097\/01.ASN.0000033611.79556.AE","volume":"13","author":"EP Bottinger","year":"2002","unstructured":"Bottinger EP, Bitzer M (2002) TGF-beta signaling in renal disease. J Am Soc Nephrol 13:2600\u20132610","journal-title":"J Am Soc Nephrol"},{"key":"647_CR31","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1046\/j.1523-1755.2002.00137.x","volume":"61","author":"Y Wada","year":"2002","unstructured":"Wada Y, Morioka T, Oyanagi-Tanaka Y et al (2002) Impairment of vascular regeneration precedes progressive glomerulosclerosis in anti-Thy 1.1. glomerulonephritis. Kidney Int 61:432\u2013443","journal-title":"Kidney Int"},{"issue":"3\u20134","key":"647_CR32","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1159\/000174072","volume":"19","author":"A Bohle","year":"1996","unstructured":"Bohle A, Mackensen-Haen S, Wehrmann M (1996) Significance of postglomerular capillaries in the pathogenesis of chronic renal failure. Kidney Blood Press Res, 19(3\u20134):191\u2013195","journal-title":"Kidney Blood Press Res,"},{"issue":"7","key":"647_CR33","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1038\/sj.ki.5000060","volume":"69","author":"A Remuzzi","year":"2006","unstructured":"Remuzzi A, Gagliardini E, Sangalli F et al (2006) ACE inhibition reduces glomerulosclerosis and regenerates glomerular tissue in a model of progressive renal disease. Kidney Int 69(7):1124\u20131130 April (1)","journal-title":"Kidney Int"},{"key":"647_CR34","doi-asserted-by":"crossref","first-page":"3063","DOI":"10.1097\/01.ASN.0000146121.72699.86","volume":"15","author":"M Adamczak","year":"2004","unstructured":"Adamczak M, Gross ML, Amann K et al (2004) Reversal of glomerular lesions involves coordinated restructuring of glomerular microvasculature. J Am Soc Nephrol 15:3063\u20133072","journal-title":"J Am Soc Nephrol"},{"issue":"6","key":"647_CR35","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1159\/000074298","volume":"23","author":"K Okon","year":"2003","unstructured":"Okon K, Szumera A, Kuzniewski M (2003) Are CD34+ cells found in renal interstitial fibrosis? Am J Nephrol 23(6):409\u2013414","journal-title":"Am J Nephrol"},{"issue":"4","key":"647_CR36","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0272-6386(03)00026-X","volume":"41","author":"MM Kossi El","year":"2003","unstructured":"El Kossi MM, El Nahas AM (2003) Stem cell factor and crescentic glomerulonephritis. Am J Kidney Dis 41(4):785\u2013795","journal-title":"Am J Kidney Dis"},{"issue":"5","key":"647_CR37","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1046\/j.1523-1755.2003.00255.x","volume":"64","author":"AM Nahas El","year":"2003","unstructured":"El Nahas AM (2003) Plasticity of kidney cells: role in kidney remodeling and scarring. Kidney Int 64(5):1553\u20131465","journal-title":"Kidney Int"},{"key":"647_CR38","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1172\/JCI0215518","volume":"110","author":"M Iwano","year":"2002","unstructured":"Iwano M, Plieth D, Danoff TM et al (2002) Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 110:341\u2013350","journal-title":"J Clin Invest"},{"issue":"1","key":"647_CR39","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/ncpneph0021","volume":"1","author":"LG Cantley","year":"2005","unstructured":"Cantley LG (2005) Adult stem cells in the repair of the injured renal tubule (review). Nat Clin Prac Nephrol 1(1):22\u201332","journal-title":"Nat Clin Prac Nephrol"}],"container-title":["Virchows Archiv"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-008-0647-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00428-008-0647-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-008-0647-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T12:34:07Z","timestamp":1631622847000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00428-008-0647-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8,8]]},"references-count":39,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["647"],"URL":"https:\/\/doi.org\/10.1007\/s00428-008-0647-0","relation":{},"ISSN":["0945-6317","1432-2307"],"issn-type":[{"value":"0945-6317","type":"print"},{"value":"1432-2307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8,8]]}}}