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The histology always needs to be evaluated considering also the clinical and radiological context which remains an important cornerstone in the classification of these lesions. Nevertheless, the diagnosis of maxillofacial bone tumours is often challenging for radiologists as well as pathologists, while an accurate diagnosis is essential for adequate clinical decision-making. The integration of new molecular markers in a multidisciplinary diagnostic approach may not only increase the diagnostic accuracy but potentially also identify new druggable targets for precision medicine. The current review provides an overview of the clinicopathological and molecular findings in maxillofacial bone tumours and discusses the diagnostic value of these genetic aberrations.<\/jats:p>","DOI":"10.1007\/s00428-019-02726-2","type":"journal-article","created":{"date-parts":[[2019,12,14]],"date-time":"2019-12-14T17:02:25Z","timestamp":1576342945000},"page":"159-174","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Molecular findings in maxillofacial bone tumours and its diagnostic value"],"prefix":"10.1007","volume":"476","author":[{"given":"Arjen H.G.","family":"Cleven","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willem H.","family":"Schreuder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eline","family":"Groen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herman M.","family":"Kroon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Baumhoer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,12,14]]},"reference":[{"issue":"1","key":"2726_CR1","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1038\/s41467-018-04530-z","volume":"9","author":"MW Fittall","year":"2018","unstructured":"Fittall MW et al (2018) Recurrent rearrangements of FOS and FOSB define osteoblastoma. 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