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The main aim of this review is the description of the most frequent oddities one can encounter as foreign bodies, in gastrointestinal pathology, on the basis of the current literature and personal experience. The types of encountered substances are divided into four principal categories: parasites (helminths such as\n                    <jats:italic>Enterobius vermicularis<\/jats:italic>\n                    ,\n                    <jats:italic>Strongyloides<\/jats:italic>\n                    ,\n                    <jats:italic>Schistosoma<\/jats:italic>\n                    , and\n                    <jats:italic>Anisakis<\/jats:italic>\n                    , and protozoa such as\n                    <jats:italic>Entamoeba<\/jats:italic>\n                    ,\n                    <jats:italic>Giardia<\/jats:italic>\n                    and some intestinal coccidia); drugs and pharmaceutical fillers (found as deposits and as bystanders, innocent or not); seeds (possibly confused with worms) and plant remnants; pollutants (secondary to post-resection or post-biopsy contamination of the sample). An ample library of images is provided in order to consent easy referencing for diagnostic routine.\n                  <\/jats:p>","DOI":"10.1007\/s00428-021-03188-1","type":"journal-article","created":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T16:29:18Z","timestamp":1633105758000},"page":"231-245","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["\u201cStranger things\u201d in the gut: uncommon items in gastrointestinal specimens"],"prefix":"10.1007","volume":"480","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6477-3182","authenticated-orcid":false,"given":"Federica","family":"Grillo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8638-0080","authenticated-orcid":false,"given":"Michela","family":"Campora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6332-5756","authenticated-orcid":false,"given":"Luca","family":"Carlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Cornara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Parente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Vanoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Remo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Migliora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiocca","family":"Roberto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Fassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0193-5281","authenticated-orcid":false,"given":"Luca","family":"Mastracci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,10,1]]},"reference":[{"key":"3188_CR1","first-page":"629","volume":"21","author":"AE Mohamed","year":"2000","unstructured":"Mohamed AE, Ghandour ZM, Al-Karawi MA et al (2000) Gastrointestinal parasites presentations and histological diagnosis from endoscopic biopsies and surgical specimens. 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