{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T14:50:26Z","timestamp":1788792626643,"version":"build-2803163510"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T00:00:00Z","timestamp":1726617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T00:00:00Z","timestamp":1726617600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA008748"],"award-info":[{"award-number":["P30CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virchows Arch"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1007\/s00428-024-03837-1","type":"journal-article","created":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T14:02:19Z","timestamp":1726754539000},"page":"665-674","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Histologic spectrum and outcome of Human papillomavirus (HPV)-associated oral cavity squamous cell carcinoma: a single center experience and a survey of The Cancer Genome Atlas (TGCA) cohort"],"prefix":"10.1007","volume":"485","author":[{"given":"Ronald A.","family":"Ghossein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Snjezana","family":"Dogan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc A.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora","family":"Katabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4638-9835","authenticated-orcid":false,"given":"Bin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,18]]},"reference":[{"key":"3837_CR1","unstructured":"Amin MB, Edge SB, GF L, Brookland RK, K M, GJ E, CC C, HK R, SD C, JJ M, Brierley J, Gaspar LE, Schilsky RL, Balch CM, Winchester DP, Asare EA, Madera M, Gress DM, Meyer LR (2017) AJCC cancer staging manual. Eighth edition. Springer Nature, New York"},{"key":"3837_CR2","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/j.oraloncology.2011.05.004","volume":"47","author":"D Anantharaman","year":"2011","unstructured":"Anantharaman D, Marron M, Lagiou P, Samoli E, Ahrens W, Pohlabeln H, Slamova A, Schejbalova M, Merletti F, Richiardi L, Kjaerheim K, Castellsague X, Agudo A, Talamini R, Barzan L, Macfarlane TV, Tickle M, Simonato L, Canova C, Conway DI, McKinney PA, Thomson P, Znaor A, Healy CM, McCartan BE, Hashibe M, Brennan P, Macfarlane GJ (2011) Population attributable risk of tobacco and alcohol for upper aerodigestive tract cancer. Oral Oncol 47:725\u2013731. https:\/\/doi.org\/10.1016\/j.oraloncology.2011.05.004","journal-title":"Oral Oncol"},{"key":"3837_CR3","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1093\/ntr\/nty074","volume":"21","author":"S Asthana","year":"2019","unstructured":"Asthana S, Labani S, Kailash U, Sinha DN, Mehrotra R (2019) Association of smokeless tobacco use and oral cancer: a systematic global review and meta-analysis. Nicotine Tob Res 21:1162\u20131171. https:\/\/doi.org\/10.1093\/ntr\/nty074","journal-title":"Nicotine Tob Res"},{"key":"3837_CR4","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1038\/nature14129","volume":"517","author":"Cancer Genome Atlas N","year":"2015","unstructured":"Cancer Genome Atlas N (2015) Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature 517:576\u2013582. https:\/\/doi.org\/10.1038\/nature14129","journal-title":"Nature"},{"key":"3837_CR5","doi-asserted-by":"publisher","first-page":"djv403","DOI":"10.1093\/jnci\/djv403","volume":"108","author":"X Castellsague","year":"2016","unstructured":"Castellsague X, Alemany L, Quer M, Halec G, Quiros B, Tous S, Clavero O, Alos L, Biegner T, Szafarowski T, Alejo M, Holzinger D, Cadena E, Claros E, Hall G, Laco J, Poljak M, Benevolo M, Kasamatsu E, Mehanna H, Ndiaye C, Guimera N, Lloveras B, Leon X, Ruiz-Cabezas JC, Alvarado-Cabrero I, Kang CS, Oh JK, Garcia-Rojo M, Iljazovic E, Ajayi OF, Duarte F, Nessa A, Tinoco L, Duran-Padilla MA, Pirog EC, Viarheichyk H, Morales H, Costes V, Felix A, Germar MJ, Mena M, Ruacan A, Jain A, Mehrotra R, Goodman MT, Lombardi LE, Ferrera A, Malami S, Albanesi EI, Dabed P, Molina C, Lopez-Revilla R, Mandys V, Gonzalez ME, Velasco J, Bravo IG, Quint W, Pawlita M, Munoz N, de Sanjose S, Xavier Bosch F, Head ICOIHi, Neck cancer study G (2016) HPV involvement in head and neck cancers: comprehensive assessment of biomarkers in 3680 patients. J Natl Cancer Inst 108:djv403. https:\/\/doi.org\/10.1093\/jnci\/djv403","journal-title":"J Natl Cancer Inst"},{"key":"3837_CR6","doi-asserted-by":"publisher","first-page":"1760","DOI":"10.1002\/lary.29996","volume":"132","author":"S Christianto","year":"2022","unstructured":"Christianto S, Li KY, Huang TH, Su YX (2022) The prognostic value of human papilloma virus infection in oral cavity squamous cell carcinoma: a meta-analysis. Laryngoscope 132:1760\u20131770. https:\/\/doi.org\/10.1002\/lary.29996","journal-title":"Laryngoscope"},{"key":"3837_CR7","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1186\/s12885-018-4247-3","volume":"18","author":"PM de Abreu","year":"2018","unstructured":"de Abreu PM, Co ACG, Azevedo PL, do Valle IB, de Oliveira KG, Gouvea SA, Cordeiro-Silva MF, Louro ID, de Podesta JRV, Lenzi J, Sena A, Mendonca EF, von Zeidler SLV (2018) Frequency of HPV in oral cavity squamous cell carcinoma. BMC Cancer 18:324. https:\/\/doi.org\/10.1186\/s12885-018-4247-3","journal-title":"BMC Cancer"},{"key":"3837_CR8","doi-asserted-by":"publisher","first-page":"3152","DOI":"10.1200\/JCO.18.00684","volume":"36","author":"C Fakhry","year":"2018","unstructured":"Fakhry C, Lacchetti C, Rooper LM, Jordan RC, Rischin D, Sturgis EM, Bell D, Lingen MW, Harichand-Herdt S, Thibo J, Zevallos J, Perez-Ordonez B (2018) Human papillomavirus testing in head and neck carcinomas: ASCO clinical practice guideline endorsement of the college of american pathologists guideline Journal of clinical oncology\u202f: official journal of the American Society of. Clin Oncol 36:3152\u20133161. https:\/\/doi.org\/10.1200\/JCO.18.00684","journal-title":"Clin Oncol"},{"key":"3837_CR9","doi-asserted-by":"publisher","first-page":"pl1","DOI":"10.1126\/scisignal.2004088","volume":"6","author":"J Gao","year":"2013","unstructured":"Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, Sun Y, Jacobsen A, Sinha R, Larsson E, Cerami E, Sander C, Schultz N (2013) Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal 6:pl1. https:\/\/doi.org\/10.1126\/scisignal.2004088","journal-title":"Sci Signal"},{"key":"3837_CR10","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1097\/PAS.0b013e3181b6d8e6","volume":"33","author":"VY Jo","year":"2009","unstructured":"Jo VY, Mills SE, Stoler MH, Stelow EB (2009) Papillary squamous cell carcinoma of the head and neck: frequent association with human papillomavirus infection and invasive carcinoma. Am J Surg Pathol 33:1720\u20131724. https:\/\/doi.org\/10.1097\/PAS.0b013e3181b6d8e6","journal-title":"Am J Surg Pathol"},{"key":"3837_CR11","doi-asserted-by":"publisher","unstructured":"Katirachi SK, Gronlund MP, Jakobsen KK, Gronhoj C, von Buchwald C (2023) The prevalence of HPV in oral cavity squamous cell carcinoma. Viruses 15. https:\/\/doi.org\/10.3390\/v15020451","DOI":"10.3390\/v15020451"},{"issue":"Suppl 1","key":"3837_CR12","doi-asserted-by":"publisher","first-page":"E1794","DOI":"10.1002\/hed.24319","volume":"38","author":"B Kumar","year":"2016","unstructured":"Kumar B, Cipolla MJ, Old MO, Brown NV, Kang SY, Dziegielewski PT, Durmus K, Ozer E, Agrawal A, Carrau RL, Schuller DE, Leon ME, Pan Q, Kumar P, Wood V, Burgers J, Wakely PE Jr, Teknos TN (2016) Surgical management of oropharyngeal squamous cell carcinoma: survival and functional outcomes. Head Neck 38(Suppl 1):E1794-1802. https:\/\/doi.org\/10.1002\/hed.24319","journal-title":"Head Neck"},{"key":"3837_CR13","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1038\/nrc.2018.11","volume":"18","author":"CR Leemans","year":"2018","unstructured":"Leemans CR, Snijders PJF, Brakenhoff RH (2018) The molecular landscape of head and neck cancer. Nat Rev Cancer 18:269\u2013282. https:\/\/doi.org\/10.1038\/nrc.2018.11","journal-title":"Nat Rev Cancer"},{"key":"3837_CR14","doi-asserted-by":"publisher","first-page":"S44","DOI":"10.1038\/modpathol.2016.152","volume":"30","author":"JS Lewis Jr","year":"2017","unstructured":"Lewis JS Jr (2017) Morphologic diversity in human papillomavirus-related oropharyngeal squamous cell carcinoma: catch me if you can! Mod Pathol: Off J U S Can Acad Pathol Inc 30:S44\u2013S53. https:\/\/doi.org\/10.1038\/modpathol.2016.152","journal-title":"Mod Pathol: Off J U S Can Acad Pathol Inc"},{"key":"3837_CR15","doi-asserted-by":"publisher","first-page":"559","DOI":"10.5858\/arpa.2017-0286-CP","volume":"142","author":"JS Lewis Jr","year":"2018","unstructured":"Lewis JS Jr, Beadle B, Bishop JA, Chernock RD, Colasacco C, Lacchetti C, Moncur JT, Rocco JW, Schwartz MR, Seethala RR, Thomas NE, Westra WH, Faquin WC (2018) Human papillomavirus testing in head and neck carcinomas: guideline from the College of American Pathologists. Arch Pathol Lab Med 142:559\u2013597. https:\/\/doi.org\/10.5858\/arpa.2017-0286-CP","journal-title":"Arch Pathol Lab Med"},{"key":"3837_CR16","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1007\/s12105-022-01467-0","volume":"16","author":"JS Lewis Jr","year":"2022","unstructured":"Lewis JS Jr, Smith MH, Wang X, Tong F, Mehrad M, Lang-Kuhs KA (2022) Human papillomavirus-associated oral cavity squamous cell carcinoma: an entity with distinct morphologic and clinical features. Head Neck Pathol 16:1073\u20131081. https:\/\/doi.org\/10.1007\/s12105-022-01467-0","journal-title":"Head Neck Pathol"},{"key":"3837_CR17","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1001\/jamaoto.2018.0395","volume":"144","author":"H Li","year":"2018","unstructured":"Li H, Torabi SJ, Yarbrough WG, Mehra S, Osborn HA, Judson B (2018) Association of human papillomavirus status at head and neck carcinoma subsites with overall survival. JAMA Otolaryngol-- Head Neck Surg 144:519\u2013525. https:\/\/doi.org\/10.1001\/jamaoto.2018.0395","journal-title":"JAMA Otolaryngol-- Head Neck Surg"},{"key":"3837_CR18","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1016\/s1470-2045(10)70017-6","volume":"11","author":"S Marur","year":"2010","unstructured":"Marur S, D\u2019Souza G, Westra WH, Forastiere AA (2010) HPV-associated head and neck cancer: a virus-related cancer epidemic. Lancet Oncol 11:781\u2013789. https:\/\/doi.org\/10.1016\/s1470-2045(10)70017-6","journal-title":"Lancet Oncol"},{"key":"3837_CR19","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1007\/s12105-011-0245-3","volume":"5","author":"RP Masand","year":"2011","unstructured":"Masand RP, El-Mofty SK, Ma XJ, Luo Y, Flanagan JJ, Lewis JS Jr (2011) Adenosquamous carcinoma of the head and neck: relationship to human papillomavirus and review of the literature. Head Neck Pathol 5:108\u2013116. https:\/\/doi.org\/10.1007\/s12105-011-0245-3","journal-title":"Head Neck Pathol"},{"key":"3837_CR20","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.oooo.2013.01.020","volume":"115","author":"C McCord","year":"2013","unstructured":"McCord C, Xu J, Xu W, Qiu X, McComb RJ, Perez-Ordonez B, Bradley G (2013) Association of high-risk human papillomavirus infection with oral epithelial dysplasia. Oral Surg Oral Med Oral Pathol Oral Radiol 115:541\u2013549. https:\/\/doi.org\/10.1016\/j.oooo.2013.01.020","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"3837_CR21","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1097\/PAS.0b013e318290427d","volume":"37","author":"M Mehrad","year":"2013","unstructured":"Mehrad M, Carpenter DH, Chernock RD, Wang H, Ma XJ, Luo Y, Luo J, Lewis JS Jr, El-Mofty SK (2013) Papillary squamous cell carcinoma of the head and neck: clinicopathologic and molecular features with special reference to human papillomavirus. Am J Surg Pathol 37:1349\u20131356. https:\/\/doi.org\/10.1097\/PAS.0b013e318290427d","journal-title":"Am J Surg Pathol"},{"key":"3837_CR22","doi-asserted-by":"publisher","first-page":"2849","DOI":"10.1007\/s00784-019-02958-1","volume":"23","author":"FW Mello","year":"2019","unstructured":"Mello FW, Melo G, Pasetto JJ, Silva CAB, Warnakulasuriya S, Rivero ERC (2019) The synergistic effect of tobacco and alcohol consumption on oral squamous cell carcinoma: a systematic review and meta-analysis. Clin Oral Invest 23:2849\u20132859. https:\/\/doi.org\/10.1007\/s00784-019-02958-1","journal-title":"Clin Oral Invest"},{"key":"3837_CR23","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1007\/s12105-021-01402-9","volume":"16","author":"S Muller","year":"2022","unstructured":"Muller S, Tilakaratne WM (2022) Update from the 5th Edition of the World Health Organization classification of head and neck tumors: tumours of the oral cavity and mobile tongue. Head Neck Pathol 16:54\u201362. https:\/\/doi.org\/10.1007\/s12105-021-01402-9","journal-title":"Head Neck Pathol"},{"key":"3837_CR24","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1002\/ijc.33514","volume":"149","author":"IH Nauta","year":"2021","unstructured":"Nauta IH, Heideman DAM, Brink A, van der Steen B, Bloemena E, Koljenovic S, Baatenburg de Jong RJ, Leemans CR, Brakenhoff RH (2021) The unveiled reality of human papillomavirus as risk factor for oral cavity squamous cell carcinoma. Int J Cancer 149:420\u2013430. https:\/\/doi.org\/10.1002\/ijc.33514","journal-title":"Int J Cancer"},{"key":"3837_CR25","doi-asserted-by":"publisher","first-page":"529","DOI":"10.31557\/APJCP.2022.23.2.529","volume":"23","author":"F Naz","year":"2022","unstructured":"Naz F, Verma H, Tanveer N, Sudheer AK, Kakkar A, Tanwar P (2022) Demographic profile of p16 immunopositive and HPV DNA PCR positive oral squamous cell carcinoma in a large cohort of Indian patients. Asian Pac J Cancer Prev 23:529\u2013536. https:\/\/doi.org\/10.31557\/APJCP.2022.23.2.529","journal-title":"Asian Pac J Cancer Prev"},{"key":"3837_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1200\/JGO.18.00058","volume":"4","author":"V Palve","year":"2018","unstructured":"Palve V, Bagwan J, Krishnan NM, Pareek M, Chandola U, Suresh A, Siddappa G, James BL, Kekatpure V, Kuriakose MA, Panda B (2018) Detection of high-risk human papillomavirus in oral cavity squamous cell carcinoma using multiple analytes and their role in patient survival. J Glob Oncol 4:1\u201333. https:\/\/doi.org\/10.1200\/JGO.18.00058","journal-title":"J Glob Oncol"},{"key":"3837_CR27","doi-asserted-by":"publisher","first-page":"e150","DOI":"10.4317\/medoral.25092","volume":"27","author":"E Perez-Islas","year":"2022","unstructured":"Perez-Islas E, Garcia-Carranca A, Acosta-Gio E, Reynoso-Noveron N, Maldonado-Martinez HA, Guido-Jimenez M, Sobrevilla-Moreno N, Granados-Garcia M, Perez-Baez WB, Vilar-Compte D (2022) Prognostic importance of DNA from human papillomavirus in patients with oral squamous cell carcinoma. Med Oral Patol Oral Cir Bucal 27:e150\u2013e158. https:\/\/doi.org\/10.4317\/medoral.25092","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"3837_CR28","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1097\/PAS.0000000000001433","volume":"44","author":"LM Rooper","year":"2020","unstructured":"Rooper LM, Windon MJ, Hernandez T, Miles B, Ha PK, Ryan WR, Van Zante A, Eisele DW, D\u2019Souza G, Fakhry C, Westra WH (2020) HPV-positive squamous cell carcinoma of the larynx, oral cavity, and hypopharynx: clinicopathologic characterization with recognition of a novel warty variant. Am J Surg Pathol 44:691\u2013702. https:\/\/doi.org\/10.1097\/PAS.0000000000001433","journal-title":"Am J Surg Pathol"},{"key":"3837_CR29","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1001\/jamaoto.2020.3382","volume":"146","author":"A Sahovaler","year":"2020","unstructured":"Sahovaler A, Kim MH, Mendez A, Palma D, Fung K, Yoo J, Nichols AC, MacNeil SD (2020) Survival outcomes in human papillomavirus-associated nonoropharyngeal squamous cell carcinomas: a systematic review and meta-analysis. JAMA Otolaryngol-- Head Neck Surg 146:1158\u20131166. https:\/\/doi.org\/10.1001\/jamaoto.2020.3382","journal-title":"JAMA Otolaryngol-- Head Neck Surg"},{"key":"3837_CR30","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1111\/odi.13920","volume":"29","author":"W Saleh","year":"2023","unstructured":"Saleh W, Cha S, Banasser A, Fitzpatrick SG, Bhattacharyya I, Youssef JM, Anees MM, Elzahaby IA, Katz J (2023) Localization and characterization of human papillomavirus-16 in oral squamous cell carcinoma. Oral Dis 29:436\u2013444. https:\/\/doi.org\/10.1111\/odi.13920","journal-title":"Oral Dis"},{"key":"3837_CR31","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1007\/s10147-023-02327-9","volume":"28","author":"H Shigeishi","year":"2023","unstructured":"Shigeishi H (2023) Association between human papillomavirus and oral cancer: a literature review. Int J Clin Oncol 28:982\u2013989. https:\/\/doi.org\/10.1007\/s10147-023-02327-9","journal-title":"Int J Clin Oncol"},{"key":"3837_CR32","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1002\/cre2.342","volume":"7","author":"TM Soland","year":"2021","unstructured":"Soland TM, Bjerkli IH, Georgsen JB, Schreurs O, Jebsen P, Laurvik H, Sapkota D (2021) High-risk human papilloma virus was not detected in a Norwegian cohort of oral squamous cell carcinoma of the mobile tongue. Clin Exp Dent Res 7:70\u201377. https:\/\/doi.org\/10.1002\/cre2.342","journal-title":"Clin Exp Dent Res"},{"key":"3837_CR33","doi-asserted-by":"publisher","unstructured":"Tang KD, Menezes L, Baeten K, Walsh LJ, Whitfield BCS, Batstone MD, Kenny L, Frazer IH, Scheper GC, Punyadeera C (2020) Oral HPV16 prevalence in oral potentially malignant disorders and oral cavity cancers. Biomolecules 10. https:\/\/doi.org\/10.3390\/biom10020223","DOI":"10.3390\/biom10020223"},{"key":"3837_CR34","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1111\/odi.13084","volume":"25","author":"AC Vidal Loustau","year":"2019","unstructured":"Vidal Loustau AC, Dulguerov N, Curvoisier D, McKee T, Lombardi T (2019) Low prevalence of HPV-induced oral squamous cell carcinoma in Geneva Switzerland. Oral Dis 25:1283\u20131290. https:\/\/doi.org\/10.1111\/odi.13084","journal-title":"Oral Dis"},{"key":"3837_CR35","doi-asserted-by":"publisher","first-page":"105175","DOI":"10.1016\/j.oraloncology.2020.105175","volume":"116","author":"E Yilmaz","year":"2021","unstructured":"Yilmaz E, Ozbun MA, Gan GN (2021) Molecular and immune signature of HPV-positive oral cavity squamous cell carcinoma. Oral Oncol 116:105175. https:\/\/doi.org\/10.1016\/j.oraloncology.2020.105175","journal-title":"Oral Oncol"},{"key":"3837_CR36","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.oraloncology.2016.03.003","volume":"56","author":"ME Zafereo","year":"2016","unstructured":"Zafereo ME, Xu L, Dahlstrom KR, Viamonte CA, El-Naggar AK, Wei Q, Li G, Sturgis EM (2016) Squamous cell carcinoma of the oral cavity often overexpresses p16 but is rarely driven by human papillomavirus. Oral Oncol 56:47\u201353. https:\/\/doi.org\/10.1016\/j.oraloncology.2016.03.003","journal-title":"Oral Oncol"},{"key":"3837_CR37","doi-asserted-by":"publisher","first-page":"e0205406","DOI":"10.1371\/journal.pone.0205406","volume":"13","author":"AP Zammit","year":"2018","unstructured":"Zammit AP, Sinha R, Cooper CL, Perry CFL, Frazer IH, Tuong ZK (2018) Examining the contribution of smoking and HPV towards the etiology of oral cavity squamous cell carcinoma using high-throughput sequencing: a prospective observational study. PLoS ONE 13:e0205406. https:\/\/doi.org\/10.1371\/journal.pone.0205406","journal-title":"PLoS ONE"}],"container-title":["Virchows Archiv"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-024-03837-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00428-024-03837-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-024-03837-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T12:11:38Z","timestamp":1730203898000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00428-024-03837-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,18]]},"references-count":37,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["3837"],"URL":"https:\/\/doi.org\/10.1007\/s00428-024-03837-1","relation":{},"ISSN":["0945-6317","1432-2307"],"issn-type":[{"value":"0945-6317","type":"print"},{"value":"1432-2307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,18]]},"assertion":[{"value":"4 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 May 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 May 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 September 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The research is approved by the Institutional Review Board (IRB 17\u2013103) of Memorial Sloan Kettering Cancer Center.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The content is solely the responsibility of the authors and does not necessarily reflect the official views of the National Institutes of Health.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}