{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:46:19Z","timestamp":1787168779408,"version":"build-2736575974"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virchows Arch"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1007\/s00428-024-04000-6","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T19:37:02Z","timestamp":1734550622000},"page":"1339-1343","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Interstitial lipoid pneumonia\u2014A complication of intravenous administration of lipid emulsions in critically ill patients"],"prefix":"10.1007","volume":"486","author":[{"given":"E. M. V.","family":"de Cuba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Vreuls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. G.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. B.","family":"Flieder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0243-4657","authenticated-orcid":false,"given":"E.","family":"Thunnissen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,19]]},"reference":[{"key":"4000_CR1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1007\/s13181-011-0187-x","volume":"8","author":"A-J Geib","year":"2012","unstructured":"Geib A-J, Liebelt E, Manini AF, Toxicology Investigators\u2019 Consortium (ToxIC) (2012) Clinical experience with intravenous lipid emulsion for drug-induced cardiovascular collapse. J Med Toxicol 8:10\u201314. https:\/\/doi.org\/10.1007\/s13181-011-0187-x","journal-title":"J Med Toxicol"},{"key":"4000_CR2","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1177\/0748233713518601","volume":"32","author":"M Moshiri","year":"2016","unstructured":"Moshiri M, Vahabzadeh M, Mohammadpour AH, Hosseinzadeh H (2016) Evaluation of intravenous lipid emulsion on haloperidol-induced hypotension in rabbits. Toxicol Ind Health 32:945\u2013952. https:\/\/doi.org\/10.1177\/0748233713518601","journal-title":"Toxicol Ind Health"},{"key":"4000_CR3","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1136\/adc.66.1_Spec_No.26","volume":"66","author":"JW Puntis","year":"1991","unstructured":"Puntis JW, Rushton DI (1991) Pulmonary intravascular lipid in neonatal necropsy specimens. Arch Dis Child 66:26\u201328","journal-title":"Arch Dis Child"},{"key":"4000_CR4","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1136\/jcp.49.5.391","volume":"49","author":"S Variend","year":"1996","unstructured":"Variend S, Drummond A, Coombs R (1996) Splenic macrophages in preterm infants: a necropsy study. J Clin Pathol 49:391\u2013394","journal-title":"J Clin Pathol"},{"key":"4000_CR5","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1164\/rccm.200305-620OC","volume":"169","author":"ME Lekka","year":"2004","unstructured":"Lekka ME, Liokatis S, Nathanail C et al (2004) The impact of intravenous fat emulsion administration in acute lung injury. Am J Respir Crit Care Med 169:638\u2013644. https:\/\/doi.org\/10.1164\/rccm.200305-620OC","journal-title":"Am J Respir Crit Care Med"},{"key":"4000_CR6","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/1476-511X-7-39","volume":"7","author":"J Sabater","year":"2008","unstructured":"Sabater J, Masclans JR, Sacanell J et al (2008) Effects on hemodynamics and gas exchange of omega-3 fatty acid-enriched lipid emulsion in acute respiratory distress syndrome (ARDS): a prospective, randomized, double-blind, parallel group study. Lipids Health Dis 7:39. https:\/\/doi.org\/10.1186\/1476-511X-7-39","journal-title":"Lipids Health Dis"},{"key":"4000_CR7","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1097\/00003246-200108000-00012","volume":"29","author":"U Suchner","year":"2001","unstructured":"Suchner U, Katz DP, F\u00fcrst P et al (2001) Effects of intravenous fat emulsions on lung function in patients with acute respiratory distress syndrome or sepsis. Crit Care Med 29:1569\u20131574","journal-title":"Crit Care Med"},{"key":"4000_CR8","doi-asserted-by":"publisher","first-page":"R85","DOI":"10.1186\/cc13850","volume":"18","author":"M Hecker","year":"2014","unstructured":"Hecker M, Ott J, Sondermann C et al (2014) Immunomodulation by fish-oil containing lipid emulsions in murine acute respiratory distress syndrome. Crit Care 18:R85. https:\/\/doi.org\/10.1186\/cc13850","journal-title":"Crit Care"},{"key":"4000_CR9","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1172\/JCI109046","volume":"61","author":"CR McKeen","year":"1978","unstructured":"McKeen CR, Brigham KL, Bowers RE, Harris TR (1978) Pulmonary vascular effects of fat emulsion infusion in unanesthetized sheep Prevention by indomethacin. J Clin Invest 61:1291\u20131297. https:\/\/doi.org\/10.1172\/JCI109046","journal-title":"J Clin Invest"},{"key":"4000_CR10","doi-asserted-by":"publisher","first-page":"743842","DOI":"10.1155\/2013\/743842","volume":"2013","author":"AC Essenmacher","year":"2013","unstructured":"Essenmacher AC, Astani SA (2013) Respiratory Disease following Illicit Injection of Silicone: A Case Report. Case Rep Med 2013:743842. https:\/\/doi.org\/10.1155\/2013\/743842","journal-title":"Case Rep Med"},{"key":"4000_CR11","doi-asserted-by":"publisher","first-page":"60","DOI":"10.12659\/PJR.883631","volume":"77","author":"M Pielaszkiewicz-Wydra","year":"2012","unstructured":"Pielaszkiewicz-Wydra M, Homola-Piekarska B, Szcze\u015bniak E et al (2012) Exogenous lipoid pneumonia - a case report of a fire-eater. Pol J Radiol 77:60\u201364","journal-title":"Pol J Radiol"},{"key":"4000_CR12","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1136\/adc.53.3.218","volume":"53","author":"AJ Barson","year":"1978","unstructured":"Barson AJ, Chistwick ML, Doig CM (1978) Fat embolism in infancy after intravenous fat infusions. Arch Dis Child 53:218\u2013223","journal-title":"Arch Dis Child"},{"key":"4000_CR13","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1097\/TA.0b013e3182208280","volume":"71","author":"EA Eriksson","year":"2011","unstructured":"Eriksson EA, Pellegrini DC, Vanderkolk WE et al (2011) Incidence of pulmonary fat embolism at autopsy: an undiagnosed epidemic. J Trauma 71:312\u2013315. https:\/\/doi.org\/10.1097\/TA.0b013e3182208280","journal-title":"J Trauma"},{"key":"4000_CR14","first-page":"173","volume":"53","author":"M Deacu","year":"2012","unstructured":"Deacu M, Tofolean DE, Bo\u015foteanu M et al (2012) Pulmonary alveolar lipoproteinosis associated with emphysematous areas. Rom J Morphol Embryol 53:173\u2013177","journal-title":"Rom J Morphol Embryol"},{"key":"4000_CR15","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1097\/00000478-199101000-00005","volume":"15","author":"P Randhawa","year":"1991","unstructured":"Randhawa P, Hoagland MH, Yousem SA (1991) Diffuse panbronchiolitis in North America. Report of three cases and review of the literature. Am J Surg Pathol 15:43\u201347","journal-title":"Am J Surg Pathol"},{"key":"4000_CR16","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1111\/j.1365-2559.2006.02355.x","volume":"48","author":"AG Nicholson","year":"2006","unstructured":"Nicholson AG, Florio R, Hansell DM et al (2006) Pulmonary involvement by Niemann-Pick disease. A report of six cases. Histopathology 48:596\u2013603. https:\/\/doi.org\/10.1111\/j.1365-2559.2006.02355.x","journal-title":"Histopathology"},{"key":"4000_CR17","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1016\/S0046-8177(99)90092-8","volume":"30","author":"G Amir","year":"1999","unstructured":"Amir G, Ron N (1999) Pulmonary pathology in Gaucher\u2019s disease. Hum Pathol 30:666\u2013670","journal-title":"Hum Pathol"},{"key":"4000_CR18","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1159\/000091609","volume":"73","author":"DM Pierson","year":"2006","unstructured":"Pierson DM, Ionescu D, Qing G et al (2006) Pulmonary fibrosis in hermansky-pudlak syndrome. a case report and review. Respiration 73:382\u2013395. https:\/\/doi.org\/10.1159\/000091609","journal-title":"Respiration"},{"key":"4000_CR19","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9781139018760","volume-title":"Spencer's Pathology of the Lung","author":"P Hasleton","year":"2013","unstructured":"Hasleton P, Flieder DB (2013) Spencer\u2019s Pathology of the Lung. Cambridge University Press"},{"key":"4000_CR20","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1097\/00000478-199901000-00002","volume":"23","author":"AJ Egan","year":"1999","unstructured":"Egan AJ, Boardman LA, Tazelaar HD et al (1999) Erdheim-Chester disease: clinical, radiologic, and histopathologic findings in five patients with interstitial lung disease. Am J Surg Pathol 23:17\u201326","journal-title":"Am J Surg Pathol"},{"key":"4000_CR21","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1183\/09059180.00005714","volume":"23","author":"A Baloira","year":"2014","unstructured":"Baloira A, N\u00fa\u00f1ez M, Tumbeiro M et al (2014) Pulmonary hypertension associated with Whipple disease. Eur Respir Rev 23:533\u2013536. https:\/\/doi.org\/10.1183\/09059180.00005714","journal-title":"Eur Respir Rev"},{"key":"4000_CR22","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1136\/jcp.2004.018176","volume":"58","author":"P Dunn","year":"2005","unstructured":"Dunn P, Kuo M-C, Sun C-F (2005) Pseudo-Gaucher cells in mycobacterial infection: a report of two cases. J Clin Pathol 58:1113\u20131114. https:\/\/doi.org\/10.1136\/jcp.2004.018176","journal-title":"J Clin Pathol"},{"key":"4000_CR23","doi-asserted-by":"publisher","first-page":"667","DOI":"10.3978\/j.issn.2072-1439.2012.06.08","volume":"4","author":"N Nacca","year":"2012","unstructured":"Nacca N, Bhamidipati CM, Yuhico LS et al (2012) Severe amiodarone induced pulmonary toxicity. J Thorac Dis 4:667\u2013670. https:\/\/doi.org\/10.3978\/j.issn.2072-1439.2012.06.08","journal-title":"J Thorac Dis"},{"key":"4000_CR24","doi-asserted-by":"publisher","first-page":"bcr2006068296","DOI":"10.1136\/bcr.2006.068296","volume":"2009","author":"BD Fox","year":"2009","unstructured":"Fox BD, Shechtman I, Shitrit D et al (2009) A \u201cfat chance\u201d it\u2019s malignant: lipoid pneumonia simulating lung cancer on PET scan. BMJ Case Rep 2009:bcr2006068296. https:\/\/doi.org\/10.1136\/bcr.2006.068296","journal-title":"BMJ Case Rep"},{"key":"4000_CR25","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1111\/1556-4029.12677","volume":"60","author":"E Moreau","year":"2015","unstructured":"Moreau E, R\u00e9rolle C, Deveaux M et al (2015) Exogenous lipoid pneumonia as a contributory factor in a drug-related death. J Forensic Sci 60:514\u2013517. https:\/\/doi.org\/10.1111\/1556-4029.12677","journal-title":"J Forensic Sci"},{"key":"4000_CR26","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1053\/rmed.2000.0942","volume":"94","author":"OA Minai","year":"2000","unstructured":"Minai OA, Sullivan EJ, Stoller JK (2000) Pulmonary involvement in Niemann-Pick disease: case report and literature review. Respir Med 94:1241\u20131251. https:\/\/doi.org\/10.1053\/rmed.2000.0942","journal-title":"Respir Med"}],"container-title":["Virchows Archiv"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-024-04000-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00428-024-04000-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-024-04000-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T01:57:58Z","timestamp":1751335078000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00428-024-04000-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,19]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["4000"],"URL":"https:\/\/doi.org\/10.1007\/s00428-024-04000-6","relation":{},"ISSN":["0945-6317","1432-2307"],"issn-type":[{"value":"0945-6317","type":"print"},{"value":"1432-2307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,19]]},"assertion":[{"value":"1 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 December 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 December 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None of the authors have financial or non-financial interests that are directly or indirectly related to the work submitted for publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}