{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T06:45:00Z","timestamp":1782456300810,"version":"3.54.5"},"reference-count":74,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:00:00Z","timestamp":1760140800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:00:00Z","timestamp":1760140800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virchows Arch"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1007\/s00428-025-04282-4","type":"journal-article","created":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:47:01Z","timestamp":1760219221000},"page":"1025-1034","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["STR genotyping diagnosis of hydatidiform moles: an assessment of 2871 consecutive products of conceptions"],"prefix":"10.1007","volume":"487","author":[{"given":"Razie","family":"Amraei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchel","family":"Clark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Ratner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Buza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6285-7817","authenticated-orcid":false,"given":"Pei","family":"Hui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,11]]},"reference":[{"key":"4282_CR1","doi-asserted-by":"crossref","unstructured":"Hui P (2012) Gestational trophoblastic disease: diagnostic and molecular genetic pathology: 161\u201378","DOI":"10.1007\/978-1-61779-394-3_11"},{"key":"4282_CR2","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1016\/j.ygyno.2008.09.005","volume":"112","author":"RS Berkowitz","year":"2009","unstructured":"Berkowitz RS, Goldstein DP (2009) Current management of gestational trophoblastic diseases. Gynecol Oncol 112:654\u2013662","journal-title":"Gynecol Oncol"},{"key":"4282_CR3","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1016\/j.fertnstert.2019.06.015","volume":"112","author":"MK Maisenbacher","year":"2019","unstructured":"Maisenbacher MK, Merrion K, Kutteh WH (2019) Single-nucleotide polymorphism microarray detects molar pregnancies in 3% of miscarriages. Fertil Steril 112:700\u2013706","journal-title":"Fertil Steril"},{"key":"4282_CR4","first-page":"902","volume":"51","author":"CM Feltmate","year":"2006","unstructured":"Feltmate CM, Growdon WB, Wolfberg AJ, Goldstein DP, Genest DR et al (2006) J Reprod Med 51:902\u2013906","journal-title":"J Reprod Med"},{"key":"4282_CR5","first-page":"764","volume":"51","author":"BW Hancock","year":"2006","unstructured":"Hancock BW, Nazir K, Everard JE (2006) J Reprod Med 51:764\u2013766","journal-title":"J Reprod Med"},{"key":"4282_CR6","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1111\/j.1479-828X.2006.00539.x","volume":"46","author":"S Wiesma","year":"2006","unstructured":"Wiesma S, Kerkmeijer L, Bekkers R, Pyman J, Tan J, Quinn M (2006) Persistent trophoblast disease following partial molar pregnancy. Aust N Z J Obstet Gynaecol 46:119\u2013123","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"4282_CR7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0142545","volume":"10","author":"NB Scholz","year":"2015","unstructured":"Scholz NB, Bolund L, Nyegaard M, Faaborg L, J\u00f8rgensen MW et al (2015) Triploidy\u2014observations in 154 diandric cases. PLoS ONE 10:e0142545","journal-title":"PLoS ONE"},{"key":"4282_CR8","unstructured":"Bartosch C, Nadal A, Braga AC, Salerno A, Rougemont AL, et al (2023)\u00a0Virchows Arch"},{"key":"4282_CR9","doi-asserted-by":"publisher","DOI":"10.1136\/bmjmed-2022-000321","author":"CM Joyce","year":"2022","unstructured":"Joyce CM, Fitzgerald B, McCarthy TV, Coulter J, O\u2019Donoghue K (2022) Advances in the diagnosis and early management of gestational trophoblastic disease. BMJ Med. https:\/\/doi.org\/10.1136\/bmjmed-2022-000321","journal-title":"BMJ Med"},{"key":"4282_CR10","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1097\/PGP.0b013e3182626011","volume":"32","author":"N Buza","year":"2013","unstructured":"Buza N, Hui P (2013) Partial hydatidiform mole. Int J Gynecol Pathol 32:307\u2013315","journal-title":"Int J Gynecol Pathol"},{"key":"4282_CR11","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1146\/annurev-pathol-052016-100237","volume":"12","author":"P Hui","year":"2017","unstructured":"Hui P, Buza N, Murphy KM, Ronnett BM (2017) Hydatidiform Moles: Genetic Basis and Precision Diagnosis. Annu Rev Pathol 12:449\u2013485","journal-title":"Annu Rev Pathol"},{"key":"4282_CR12","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1097\/01.pas.0000157996.23059.c1","volume":"29","author":"M Fukunaga","year":"2005","unstructured":"Fukunaga M, Katabuchi H, Nagasaka T, Mikami Y, Minamiguchi S, Lage JM (2005) Interobserver and Intraobserver Variability in the Diagnosis of Hydatidiform Mole. Am J Surg Pathol 29:942\u2013947","journal-title":"Am J Surg Pathol"},{"key":"4282_CR13","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1097\/PAS.0b013e31825ea736","volume":"36","author":"M Gupta","year":"2012","unstructured":"Gupta M, Vang R, Yemelyanova AV, Kurman RJ, Li FR (2012) Diagnostic Reproducibility of Hydatidiform Moles. Am J Surg Pathol 36:1747\u20131760","journal-title":"Am J Surg Pathol"},{"key":"4282_CR14","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1038\/s41379-020-00691-9","volume":"34","author":"D Xing","year":"2021","unstructured":"Xing D, Adams E, Huang J, Ronnett BM (2021) Refined diagnosis of hydatidiform moles with p57 immunohistochemistry and molecular genotyping: updated analysis of a prospective series of 2217 cases. Mod Pathol 34:961\u2013982","journal-title":"Mod Pathol"},{"key":"4282_CR15","unstructured":"Schoenen S, Delbecque K, Van Rompuy AS, Marbaix E, Noel JC, et al\u00a0 (2022) Int J Gynecol Cancer"},{"key":"4282_CR16","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.jmoldx.2019.09.006","volume":"22","author":"J Bynum","year":"2020","unstructured":"Bynum J, Batista D, Xian R, Xing D, Eshleman JR (2020) Tetraploid Partial Hydatidiform Moles. J Mol Diagn 22:90\u2013100","journal-title":"J Mol Diagn"},{"key":"4282_CR17","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.bpobgyn.2021.01.004","volume":"74","author":"RA Fisher","year":"2021","unstructured":"Fisher RA, Maher GJ (2021) Genetics of gestational trophoblastic disease. Best Pract Res Clin Obstet Gynaecol 74:29\u201341","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"4282_CR18","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1038\/modpathol.2013.143","volume":"27","author":"N Banet","year":"2014","unstructured":"Banet N, DeScipio C, Murphy KM, Beierl K, Adams E (2014) Characteristics of hydatidiform moles: analysis of a prospective series with p57 immunohistochemistry and molecular genotyping. Mod Pathol 27:238\u2013254","journal-title":"Mod Pathol"},{"key":"4282_CR19","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.5858\/arpa.2018-0226-RA","volume":"142","author":"BM Ronnett","year":"2018","unstructured":"Ronnett BM (2018) Hydatidiform Moles: Ancillary Techniques to Refine Diagnosis. Arch Pathol Lab Med 142:1485\u20131502","journal-title":"Arch Pathol Lab Med"},{"key":"4282_CR20","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1097\/00000478-200110000-00001","volume":"25","author":"DH Castrillon","year":"2001","unstructured":"Castrillon DH, Sun D, Weremowicz S, Fisher RA, Crum CP, Genest DR (2001) Discrimination of Complete Hydatidiform Mole From Its Mimics by Immunohistochemistry of the Paternally Imprinted Gene Product p57 KIP2. Am J Surg Pathol 25:1225\u20131230","journal-title":"Am J Surg Pathol"},{"issue":"5","key":"4282_CR21","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1093\/oxfordjournals.molbev.a026354","volume":"17","author":"LA Zhivotovsky","year":"2000","unstructured":"Zhivotovsky LA, Bennett L, Bowcock AM, Feldman MW (2000) Human Population Expansion and Microsatellite Variation. Mol Biol Evol 17(5):757\u2013767","journal-title":"Mol Biol Evol"},{"key":"4282_CR22","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1038\/modpathol.3800010","volume":"17","author":"CY Lai","year":"2004","unstructured":"Lai CY, Chan KY, Khoo U-S, Ngan HY, Xue W-C et al (2004) Analysis of gestational trophoblastic disease by genotyping and chromosome in situ hybridization. Mod Pathol 17:40\u201348","journal-title":"Mod Pathol"},{"key":"4282_CR23","doi-asserted-by":"publisher","first-page":"1658","DOI":"10.1038\/s41379-021-00831-9","volume":"34","author":"N Buza","year":"2021","unstructured":"Buza N, Hui P (2021) Genotyping diagnosis of gestational trophoblastic disease: frontiers in precision medicine. Mod Pathol 34:1658\u20131672","journal-title":"Mod Pathol"},{"key":"4282_CR24","unstructured":"WHO (2020)\u00a0Lyon, France: International Agnecy for Researcho on Cancer - World Health Organization Vol. 5th: p. 317\u20138"},{"key":"4282_CR25","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1111\/cge.13941","volume":"99","author":"M Rezaei","year":"2021","unstructured":"Rezaei M, Suresh B, Bereke E, Hadipour Z, Aguinaga M et al (2021) Novel pathogenic variants in <scp>NLRP7<\/scp>, <scp>NLRP5,<\/scp> and <scp>PADI6<\/scp> in patients with recurrent hydatidiform moles and reproductive failure. Clin Genet 99:823\u2013828","journal-title":"Clin Genet"},{"key":"4282_CR26","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.ygyno.2006.08.025","volume":"104","author":"I Niemann","year":"2007","unstructured":"Niemann I, Hansen ES, Sunde L (2007) The risk of persistent trophoblastic disease after hydatidiform mole classified by morphology and ploidy. Gynecol Oncol 104:411\u2013415","journal-title":"Gynecol Oncol"},{"key":"4282_CR27","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1093\/humrep\/deq052","volume":"25","author":"B Baasanjav","year":"2010","unstructured":"Baasanjav B, Usui H, Kihara M, Kaku H, Nakada E et al (2010) The risk of post-molar gestational trophoblastic neoplasia is higher in heterozygous than in homozygous complete hydatidiform moles. Hum Reprod 25:1183\u20131191","journal-title":"Hum Reprod"},{"key":"4282_CR28","doi-asserted-by":"publisher","first-page":"1979","DOI":"10.1038\/s41379-020-0566-4","volume":"33","author":"X-Z Zheng","year":"2020","unstructured":"Zheng X-Z, Qin X-Y, Chen S-W, Wang P, Zhan Y et al (2020) Heterozygous\/dispermic complete mole confers a significantly higher risk for post-molar gestational trophoblastic disease. Mod Pathol 33:1979\u20131988","journal-title":"Mod Pathol"},{"key":"4282_CR29","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1038\/s41379-019-0432-4","volume":"33","author":"Y Khawajkie","year":"2020","unstructured":"Khawajkie Y, Mechtouf N, Nguyen NMP, Rahimi K, Breguet M et al (2020) Comprehensive analysis of 204 sporadic hydatidiform moles: revisiting risk factors and their correlations with the molar genotypes. Mod Pathol 33:880\u2013892","journal-title":"Mod Pathol"},{"key":"4282_CR30","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1097\/PDM.0b013e318263f092","volume":"22","author":"H Zhong","year":"2013","unstructured":"Zhong H, Liu Y, Talmor M, Wu B, Hui P (2013) Deparaffinization and lysis by hydrothermal pressure (pressure cooking) coupled with chaotropic salt column purification. Diagn Mol Pathol 22:52\u201358","journal-title":"Diagn Mol Pathol"},{"key":"4282_CR31","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1097\/PAS.0b013e3181520034","volume":"32","author":"C Bifulco","year":"2008","unstructured":"Bifulco C, Johnson C, Hao L, Kermalli H, Bell S, Hui P (2008) Genotypic analysis of hydatidiform mole: an accurate and practical method of diagnosis. Am J Surg Pathol 32:445\u2013451","journal-title":"Am J Surg Pathol"},{"key":"4282_CR32","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1097\/AOG.0b013e3181d489ec","volume":"115","author":"F Lipata","year":"2010","unstructured":"Lipata F, Parkash V, Talmor M, Bell S, Chen S et al (2010) Precise DNA genotyping diagnosis of hydatidiform mole. Obstet Gynecol 115:784\u2013794","journal-title":"Obstet Gynecol"},{"key":"4282_CR33","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1038\/s41379-019-0266-0","volume":"32","author":"N Buza","year":"2019","unstructured":"Buza N, McGregor SM, Barroilhet L, Zheng X, Hui P (2019) Paternal uniparental isodisomy of tyrosine hydroxylase locus at chromosome 11p15.4: spectrum of phenotypical presentations simulating hydatidiform moles. Mod Pathol 32:1180\u20131188","journal-title":"Mod Pathol"},{"key":"4282_CR34","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1097\/PGP.0b013e3182a1028b","volume":"33","author":"N Buza","year":"2014","unstructured":"Buza N, Hui P (2014) Egg donor pregnancy. Int J Gynecol Pathol 33:507\u2013510","journal-title":"Int J Gynecol Pathol"},{"key":"4282_CR35","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1111\/his.15247","volume":"85","author":"A Nagy","year":"2024","unstructured":"Nagy A, Niu N, Sun T, Buza N, Hui P (2024) Histopathology 85:879\u2013888","journal-title":"Histopathology"},{"key":"4282_CR36","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1038\/286714a0","volume":"286","author":"PA Jacobs","year":"1980","unstructured":"Jacobs PA, Wilson CM, Sprenkle JA, Rosenshein NB, Migeon BR (1980) Nature 286:714\u2013716","journal-title":"Nature"},{"key":"4282_CR37","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/0165-4608(82)90096-6","volume":"5","author":"SD Lawler","year":"1982","unstructured":"Lawler SD, Fisher RA, Pickthall VJ, Povey S, Evans MW (1982) Genetic studies on hydatidiform moles. I. The origin of partial moles. Cancer Genet Cytogenet 5:309\u2013320","journal-title":"Cancer Genet Cytogenet"},{"key":"4282_CR38","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1111\/j.1469-1809.1982.tb00714.x","volume":"46","author":"PA Jacobs","year":"1982","unstructured":"Jacobs PA, Szulman AE, Funkhouser J, Matsuura JS, Wilson CC (1982) Human triploidy: relationship between parental origin of the additional haploid complement and development of partial hydatidiform mole. Ann Hum Genet 46:223\u2013231","journal-title":"Ann Hum Genet"},{"key":"4282_CR39","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/BF00304561","volume":"62","author":"DM Sheppard","year":"1982","unstructured":"Sheppard DM, Fisher RA, Lawler SD, Povey S (1982) Hum Genet 62:371\u2013374","journal-title":"Hum Genet"},{"key":"4282_CR40","first-page":"788","volume":"29","author":"AE Szulman","year":"1984","unstructured":"Szulman AE (1984) J Reprod Med 29:788\u2013791","journal-title":"J Reprod Med"},{"key":"4282_CR41","first-page":"1664","volume":"33","author":"K Ohama","year":"1981","unstructured":"Ohama K, Okamoto E, Nomura K, Fujiwara A, Fukuda Y (1981) Nippon Sanka Fujinka Gakkai Zasshi 33:1664\u20131668","journal-title":"Nippon Sanka Fujinka Gakkai Zasshi"},{"key":"4282_CR42","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/BF00278810","volume":"72","author":"U Surti","year":"1986","unstructured":"Surti U, Szulman AE, Wagner K, Leppert M, O\u2019Brien SJ (1986) Hum Genet 72:15\u201321","journal-title":"Hum Genet"},{"key":"4282_CR43","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/BF01871400","volume":"31","author":"T Kajii","year":"1986","unstructured":"Kajii T (1986) The road to diploid androgenesis. Jinrui Idengaku Zasshi 31:61\u201371","journal-title":"Jinrui Idengaku Zasshi"},{"key":"4282_CR44","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1097\/00004347-199310000-00006","volume":"12","author":"M Jeffers","year":"1993","unstructured":"Jeffers M, O\u2019Dwyer P, Curran B, Leader M, Gillan J (1993) Int J Gynecol Pathol 12:315\u2013323","journal-title":"Int J Gynecol Pathol"},{"key":"4282_CR45","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1111\/j.1471-0528.1982.tb04693.x","volume":"89","author":"PA Jacobs","year":"1982","unstructured":"Jacobs PA, Hunt PA, Matsuura JS, Wilson CC, Szulman A (1982) Complete and partial hydatidiform mole in Hawaii: cytogenetics, morphology and epidemiology. BJOG: An International Journal of Obstetrics & Gynaecology 89:258\u2013266","journal-title":"BJOG: An International Journal of Obstetrics & Gynaecology"},{"key":"4282_CR46","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1080\/0284186X.2018.1438653","volume":"57","author":"U Joneborg","year":"2018","unstructured":"Joneborg U, Folkvaljon Y, Papadogiannakis N, Lambe M, Marions L (2018) Temporal trends in incidence and outcome of hydatidiform mole: a retrospective cohort study. Acta Oncol 57:1094\u20131099","journal-title":"Acta Oncol"},{"key":"4282_CR47","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.1097\/IGC.0000000000000754","volume":"26","author":"TJ Colgan","year":"2016","unstructured":"Colgan TJ, Chang MC, Nanji S, Kolomietz E (2016) A Reappraisal of the Incidence of Placental Hydatidiform Mole Using Selective Molecular Genotyping. Int J Gynecol Cancer 26:1345\u20131350","journal-title":"Int J Gynecol Cancer"},{"key":"4282_CR48","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/j.ygyno.2016.01.005","volume":"140","author":"AA Gockley","year":"2016","unstructured":"Gockley AA, Melamed A, Joseph NT, Clapp M, Sun SY et al (2016) The effect of adolescence and advanced maternal age on the incidence of complete and partial molar pregnancy. Gynecol Oncol 140:470\u2013473","journal-title":"Gynecol Oncol"},{"key":"4282_CR49","doi-asserted-by":"publisher","first-page":"367","DOI":"10.3109\/0284186X.2010.512922","volume":"50","author":"S Salehi","year":"2011","unstructured":"Salehi S, Eloranta S, Johansson AL, Bergstr\u00f6m M, Lambe M (2011) Reporting and incidence trends of hydatidiform mole in Sweden 1973\u20132004. Acta Oncol 50:367\u2013372","journal-title":"Acta Oncol"},{"key":"4282_CR50","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1111\/j.1471-0528.2002.t01-1-01037.x","volume":"109","author":"N Sebire","year":"2002","unstructured":"Sebire N, Foskett M, Fisher R, Rees H, Seckl M, Newlands E (2002) Risk of partial and complete hydatidiform molar pregnancy in relation to maternal age. BJOG: An International Journal of Obstetrics & Gynaecology 109:99\u2013102","journal-title":"BJOG: An International Journal of Obstetrics & Gynaecology"},{"key":"4282_CR51","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/0090-8258(86)90311-2","volume":"24","author":"P Mazzanti","year":"1986","unstructured":"Mazzanti P, La Vecchia C, Parazzini F, Bolis G (1986) Frequency of hydatidiform mole in Lombardy, Northern Italy. Gynecol Oncol 24:337\u2013342","journal-title":"Gynecol Oncol"},{"key":"4282_CR52","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/S0046-8177(98)90067-3","volume":"29","author":"RW Redline","year":"1998","unstructured":"Redline RW, Hassold T, Zaragoza MV (1998) Prevalence of the partial molar phenotype in triploidy of maternal and paternal origin. Hum Pathol 29:505\u2013511","journal-title":"Hum Pathol"},{"key":"4282_CR53","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1097\/00004347-200110000-00001","volume":"20","author":"DR Genest","year":"2001","unstructured":"Genest DR (2001) Partial Hydatidiform Mole: Clinicopathological Features, Differential Diagnosis, Ploidy and Molecular Studies, and Gold Standards for Diagnosis. Int J Gynecol Pathol 20:315\u2013322","journal-title":"Int J Gynecol Pathol"},{"key":"4282_CR54","doi-asserted-by":"publisher","first-page":"1807","DOI":"10.1086\/302951","volume":"66","author":"MV Zaragoza","year":"2000","unstructured":"Zaragoza MV, Surti U, Redline RW, Millie E, Chakravarti A, Hassold TJ (2000) Parental Origin and Phenotype of Triploidy in Spontaneous Abortions: Predominance of Diandry and Association with the Partial Hydatidiform Mole. Am J Hum Genet 66:1807\u20131820","journal-title":"Am J Hum Genet"},{"key":"4282_CR55","first-page":"201","volume":"11","author":"T Borah","year":"2010","unstructured":"Borah T, Raphael V, Panda S, Saharia P (2010) Journal of Reproduction & Infertility 11:201","journal-title":"Journal of Reproduction & Infertility"},{"key":"4282_CR56","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1080\/00016340600604302","volume":"85","author":"MB Chauhan","year":"2006","unstructured":"Chauhan MB, Chaudhary P, Dahiya P, Sangwan K, Sen J (2006) Acta Obstet Gynecol Scand 85:625\u2013626","journal-title":"Acta Obstet Gynecol Scand"},{"key":"4282_CR57","first-page":"891","volume":"99","author":"NB Zite","year":"2002","unstructured":"Zite NB, Lipscomb GH, Merrill K (2002) Obstet Gynecol 99:891\u2013892","journal-title":"Obstet Gynecol"},{"key":"4282_CR58","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1080\/01443610802421734","volume":"28","author":"E Church","year":"2008","unstructured":"Church E, Hanna L, New F, Uku A, Awad H, Watson A (2008) Ovarian molar pregnancy. J Obstet Gynaecol 28:660\u2013661","journal-title":"J Obstet Gynaecol"},{"key":"4282_CR59","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1046\/j.1365-2559.2001.01151.x","volume":"38","author":"J Burton","year":"2001","unstructured":"Burton J, Lidbury E, Gillespie A, Tidy J, Smith O et al (2001) Over\u2010diagnosis of hydatidiform mole in early tubal ectopic pregnancy. Histopathology 38:409\u2013417","journal-title":"Histopathology"},{"key":"4282_CR60","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1097\/01.pgp.0000164597.19346.b5","volume":"24","author":"N Sebire","year":"2005","unstructured":"Sebire N, Lindsay I, Fisher R, Savage P, Seckl M (2005) Overdiagnosis of Complete and Partial Hydatidiform Mole in Tubal Ectopic Pregnancies. Int J Gynecol Pathol 24:260\u2013264","journal-title":"Int J Gynecol Pathol"},{"key":"4282_CR61","first-page":"351","volume":"58","author":"MC McCullough","year":"2013","unstructured":"McCullough MC, Hart S, Gilbert-Barnes E, Spellacy WN (2013) J Reprod Med 58:351\u2013353","journal-title":"J Reprod Med"},{"key":"4282_CR62","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/BF00304561","volume":"62","author":"D Sheppard","year":"1982","unstructured":"Sheppard D, Fisher RA, Lawler SD, Povey S (1982) Tetraploid conceptus with three paternal contributions. Hum Genet 62:371\u2013374","journal-title":"Hum Genet"},{"key":"4282_CR63","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1007\/BF00283043","volume":"76","author":"LO Vejerslev","year":"1987","unstructured":"Vejerslev LO, Dissing J, Hansen HE, Poulsen H (1987) Hydatidiform mole: genetic origin in polyploid conceptuses. Hum Genet 76:11\u201319","journal-title":"Hum Genet"},{"key":"4282_CR64","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1097\/PGP.0b013e31822555b3","volume":"31","author":"KM Murphy","year":"2012","unstructured":"Murphy KM, Descipio C, Wagenfuehr J, Tandy S, Mabray J et al (2012) Tetraploid Partial Hydatidiform Mole. Int J Gynecol Pathol 31:73\u201379","journal-title":"Int J Gynecol Pathol"},{"key":"4282_CR65","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/BF00278810","volume":"72","author":"U Surti","year":"1986","unstructured":"Surti U, Szulman A, Wagner K, Leppert M, O\u2019Brien SJ (1986) Hum Genet 72:15\u201321","journal-title":"Hum Genet"},{"key":"4282_CR66","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1111\/j.0001-6349.2005.00882.x","volume":"84","author":"E Ljunger","year":"2005","unstructured":"Ljunger E, Cnattingius S, Lundin C, Anner\u00e9n G (2005) Acta Obstet Gynecol Scand 84:1103\u20131107","journal-title":"Acta Obstet Gynecol Scand"},{"key":"4282_CR67","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000018041","volume":"98","author":"R Dai","year":"2019","unstructured":"Dai R, Xi Q, Wang R, Zhang H, Jiang Y et al (2019) Chromosomal copy number variations in products of conception from spontaneous abortion by next-generation sequencing technology. Medicine 98:e18041","journal-title":"Medicine"},{"key":"4282_CR68","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1097\/01.GIM.0000160075.96707.04","volume":"7","author":"J Menasha","year":"2005","unstructured":"Menasha J, Levy B, Hirschhorn K, Kardon NB (2005) Incidence and spectrum of chromosome abnormalities in spontaneous abortions: New insights from a 12-year study. Genet Med 7:251\u2013263","journal-title":"Genet Med"},{"key":"4282_CR69","doi-asserted-by":"publisher","first-page":"3233","DOI":"10.1038\/s41591-023-02645-5","volume":"29","author":"R Essers","year":"2023","unstructured":"Essers R, Lebedev IN, Kurg A, Fonova EA, Stevens SJ et al (2023) Prevalence of chromosomal alterations in first-trimester spontaneous pregnancy loss. Nat Med 29:3233\u20133242","journal-title":"Nat Med"},{"key":"4282_CR70","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1136\/jmg.2005.033571","volume":"43","author":"KA Kaiser-Rogers","year":"2006","unstructured":"Kaiser-Rogers KA, Mcfadden DE, Livasy CA, Dansereau J, Jiang R et al (2006) Androgenetic\/biparental mosaicism causes placental mesenchymal dysplasia. J Med Genet 43:187\u2013192","journal-title":"J Med Genet"},{"key":"4282_CR71","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1111\/cge.13431","volume":"94","author":"E Repnikova","year":"2018","unstructured":"Repnikova E, Roberts J, Kats A, Habeebu S, Schwager C et al (2018) Biparental\/androgenetic mosaicism in a male with features of overgrowth and placental mesenchymal dysplasia. Clin Genet 94:564\u2013568","journal-title":"Clin Genet"},{"key":"4282_CR72","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1097\/PAT.0b013e3283559c94","volume":"44","author":"JE Armes","year":"2012","unstructured":"Armes JE, McGown I, Williams M, Broomfield A, Gough K et al (2012) The placenta in Beckwith-Wiedemann syndrome: genotype-phenotype associations, excessive extravillous trophoblast and placental mesenchymal dysplasia. Pathology 44:519\u2013527","journal-title":"Pathology"},{"key":"4282_CR73","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1097\/PGP.0000000000000395","volume":"37","author":"NM Joseph","year":"2018","unstructured":"Joseph NM, Pineda C, Rabban JT (2018) DNA Genotyping of Nonmolar Donor Egg Pregnancies With Abnormal Villous Morphology: Allele Zygosity Patterns Prevent Misinterpretation as Complete Hydatidiform Mole. Int J Gynecol Pathol 37:191\u2013197","journal-title":"Int J Gynecol Pathol"},{"key":"4282_CR74","unstructured":"Zheng XZ, Qin XY, Chen SW, Wang P, Zhan Y, et al (2020)\u00a0Mod Pathol"}],"container-title":["Virchows Archiv"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-025-04282-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00428-025-04282-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-025-04282-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T08:04:38Z","timestamp":1764057878000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00428-025-04282-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,11]]},"references-count":74,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["4282"],"URL":"https:\/\/doi.org\/10.1007\/s00428-025-04282-4","relation":{},"ISSN":["0945-6317","1432-2307"],"issn-type":[{"value":"0945-6317","type":"print"},{"value":"1432-2307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,11]]},"assertion":[{"value":"6 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 September 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 September 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 October 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This work adheres to the ethical standards of the authors\u2019 institution.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}