{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T11:43:56Z","timestamp":1769427836263,"version":"3.49.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virchows Arch"],"DOI":"10.1007\/s00428-026-04412-6","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:35:45Z","timestamp":1769387745000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["B-cell marker expression in acute myeloid leukemia with plasmacytoid dendritic cell differentiation (pDC-AML) without RUNX1 lesions: An underrecognized diagnostic pitfall"],"prefix":"10.1007","author":[{"given":"Giby V.","family":"George","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neel V.","family":"Hegde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima Zahra","family":"Jelloul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Jeffrey","family":"Medeiros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1338-7107","authenticated-orcid":false,"given":"Siba","family":"El Hussein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,26]]},"reference":[{"issue":"5","key":"4412_CR1","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1182\/blood-2013-02-482497","volume":"122","author":"D Ray","year":"2013","unstructured":"Ray D, Kwon SY, Tagoh H, Heidenreich O, Ptasinska A, Bonifer C (2013) Lineage-inappropriate PAX5 expression in t(8;21) acute myeloid leukemia requires signaling-mediated abrogation of polycomb repression. Blood 122(5):759\u2013769. https:\/\/doi.org\/10.1182\/blood-2013-02-482497","journal-title":"Blood"},{"key":"4412_CR2","first-page":"S18","volume":"26","author":"GVJA George","year":"2024","unstructured":"George GVJA, Burack WR, Evans AG, Bennett JM, El Hussein S (2024) Association between B-cell marker expression and RUNX1 lesions in acute myeloid leukemia, beyond RUNX1::RUNX1T1 fusion: diagnostic pitfalls with mixed-phenotype acute leukemia\u2014B\/Myeloid. J Mol Diagn 26:S18","journal-title":"J Mol Diagn"},{"key":"4412_CR3","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17081354","author":"GV George","year":"2025","unstructured":"George GV, Kajstura M, Jajosky AN et al (2025) Association between B-cell marker expression and RUNX1 lesions in acute myeloid leukemia, beyond RUNX1::RUNX1T1 fusion: diagnostic pitfalls with mixed-phenotype acute leukemia-B\/myeloid. Cancers (Basel). https:\/\/doi.org\/10.3390\/cancers17081354","journal-title":"Cancers (Basel)"},{"key":"4412_CR4","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14143375","author":"W Wang","year":"2022","unstructured":"Wang W, Xu J, Khoury JD et al (2022) Immunophenotypic and molecular features of acute myeloid leukemia with plasmacytoid dendritic cell differentiation are distinct from blastic plasmacytoid dendritic cell neoplasm. Cancers (Basel). https:\/\/doi.org\/10.3390\/cancers14143375","journal-title":"Cancers (Basel)"},{"issue":"11","key":"4412_CR5","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1182\/blood.2022015850","volume":"140","author":"DA Arber","year":"2022","unstructured":"Arber DA, Orazi A, Hasserjian RP et al (2022) International consensus classification of myeloid neoplasms and acute leukemias: integrating morphologic, clinical, and genomic data. Blood 140(11):1200\u20131228. https:\/\/doi.org\/10.1182\/blood.2022015850","journal-title":"Blood"},{"issue":"7","key":"4412_CR6","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1038\/s41375-022-01620-2","volume":"36","author":"R Alaggio","year":"2022","unstructured":"Alaggio R, Amador C, Anagnostopoulos I et al (2022) The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms. Leukemia 36(7):1720\u20131748. https:\/\/doi.org\/10.1038\/s41375-022-01620-2","journal-title":"Leukemia"},{"key":"4412_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2019.112684","volume":"475","author":"A Orfao","year":"2019","unstructured":"Orfao A, Matarraz S, Perez-Andres M et al (2019) Immunophenotypic dissection of normal hematopoiesis. J Immunol Methods 475:112684. https:\/\/doi.org\/10.1016\/j.jim.2019.112684","journal-title":"J Immunol Methods"},{"key":"4412_CR8","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.96394","author":"AM Araujo","year":"2024","unstructured":"Araujo AM, Dekker JD, Garrison K et al (2024) Lymphoid origin of intrinsically activated plasmacytoid dendritic cells in mice. Elife. https:\/\/doi.org\/10.7554\/eLife.96394","journal-title":"Elife"},{"issue":"9","key":"4412_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2022.111260","volume":"40","author":"K Nagaharu","year":"2022","unstructured":"Nagaharu K, Kojima Y, Hirose H et al (2022) A bifurcation concept for B-lymphoid\/plasmacytoid dendritic cells with largely fluctuating transcriptome dynamics. Cell Rep 40(9):111260. https:\/\/doi.org\/10.1016\/j.celrep.2022.111260","journal-title":"Cell Rep"},{"issue":"10","key":"4412_CR10","doi-asserted-by":"publisher","first-page":"1839","DOI":"10.1182\/blood-2012-06-437863","volume":"121","author":"D Kurotaki","year":"2013","unstructured":"Kurotaki D, Osato N, Nishiyama A et al (2013) Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation. Blood 121(10):1839\u20131849. https:\/\/doi.org\/10.1182\/blood-2012-06-437863","journal-title":"Blood"},{"key":"4412_CR11","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13040764","author":"F Liss","year":"2021","unstructured":"Liss F, Frech M, Wang Y et al (2021) IRF8 is an AML-specific susceptibility factor that regulates signaling pathways and proliferation of AML cells. Cancers (Basel). https:\/\/doi.org\/10.3390\/cancers13040764","journal-title":"Cancers (Basel)"}],"container-title":["Virchows Archiv"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-026-04412-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00428-026-04412-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-026-04412-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:35:47Z","timestamp":1769387747000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00428-026-04412-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,26]]},"references-count":11,"alternative-id":["4412"],"URL":"https:\/\/doi.org\/10.1007\/s00428-026-04412-6","relation":{},"ISSN":["0945-6317","1432-2307"],"issn-type":[{"value":"0945-6317","type":"print"},{"value":"1432-2307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,26]]},"assertion":[{"value":"2 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 December 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}