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Approximately 100 cases have been reported in the English-language literature. A variety of lymphoma classifications have been described, including diffuse large B-cell lymphoma, NK\/T-cell lymphoma, Burkitt lymphoma, lymphoplasmacytic lymphoma, mucosa-associated lymphoid tissue (MALT) lymphoma, mantle cell lymphoma, marginal zone lymphoma, and peripheral T-cell lymphoma. To our knowledge, follicular lymphoma involving the larynx has been rarely reported. We report a case of a 74-year-old woman who presented with a 1-year history of hoarseness refractory to semi-occluded vocal tract (SOVT) therapy and was diagnosed with follicular lymphoma involving the false vocal fold. At presentation, the patient felt well and did not have any B symptoms. Initial computed tomography (CT) scan of the neck did not show any lesions, but a subsequent videolaryngostroboscopy revealed a small lesion in the false vocal folds. The lesion was surgically excised, and histological evaluation revealed features consistent with a diagnosis of follicular lymphoma. Herein, we present a rare case of primary follicular lymphoma of the larynx and describe its histological and immunophenotypic characteristics. Furthermore, we conducted an extensive review of the English-language literature and discuss comparable published cases.<\/jats:p>","DOI":"10.1007\/s00428-026-04443-z","type":"journal-article","created":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T08:25:11Z","timestamp":1771835111000},"page":"1019-1025","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unusual case of follicular lymphoma of vocal cord"],"prefix":"10.1007","volume":"489","author":[{"given":"Griffin H.","family":"Willman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zohre","family":"Sadeghian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyotsna","family":"Kochiyil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chieh Lin","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Trosman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulrukh","family":"Botiralieva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalya","family":"Pak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaroslav N.","family":"Chernov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shukhrat A.","family":"Abdukhalikov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Behdad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9983-9735","authenticated-orcid":false,"given":"Kirill A.","family":"Lyapichev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,23]]},"reference":[{"key":"4443_CR1","doi-asserted-by":"crossref","unstructured":"Teras LR, et al., 2016 US lymphoid malignancy statistics by World Health Organization subtypes. 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