{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T18:12:41Z","timestamp":1784052761278,"version":"3.55.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:00:00Z","timestamp":1777680000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:00:00Z","timestamp":1777680000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["Indian Council of Medical Research"],"award-info":[{"award-number":["Indian Council of Medical Research"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Virchows Arch"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1007\/s00428-026-04545-8","type":"journal-article","created":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T02:58:53Z","timestamp":1777690733000},"page":"159-170","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Thoracic inflammatory myofibroblastic tumors: A decade-long retrospective study integrating clinicopathological and molecular features from a tertiary care centre"],"prefix":"10.1007","volume":"489","author":[{"given":"Sherrin","family":"Jacob","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aruna","family":"Nambirajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hrishikesh Nagbhushan","family":"Gangule","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SH","family":"Chandrashekhara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameer","family":"Rastogi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adarsh","family":"Barwad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asit Ranjan","family":"Mridha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karan","family":"Madan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabhat Singh","family":"Malik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7589-537X","authenticated-orcid":false,"given":"Deepali","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,2]]},"reference":[{"issue":"2","key":"4545_CR1","doi-asserted-by":"publisher","first-page":"70","DOI":"10.32074\/1591-951X-213","volume":"113","author":"M Sbaraglia","year":"2021","unstructured":"Sbaraglia M, Bellan E, Dei Tos AP (2021) The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives. Pathologica 113(2):70\u201384. https:\/\/doi.org\/10.32074\/1591-951X-213","journal-title":"Pathologica"},{"issue":"4","key":"4545_CR2","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1136\/jcp.2007.049387","volume":"61","author":"JL GleasonBC, Hornick","year":"2008","unstructured":"GleasonBC,Hornick JL (2008) Inflammatory myofibroblastic tumours: where are we now? J Clin Pathol 61(4):428\u2013437. https:\/\/doi.org\/10.1136\/jcp.2007.049387","journal-title":"J Clin Pathol"},{"issue":"12","key":"4545_CR3","first-page":"2776","volume":"59","author":"CA Griffin","year":"1999","unstructured":"Griffin CA, Hawkins AL, Dvorak C, Henkle C, Ellingham T, Perlman EJ (1999) Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors. Cancer Res 59(12):2776\u20132780","journal-title":"Cancer Res"},{"issue":"6","key":"4545_CR4","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1038\/modpathol.3880352","volume":"14","author":"CM Coffin","year":"2001","unstructured":"Coffin CM, Patel A, Perkins S, Elenitoba-Johnson KS, Perlman E, Griffin CA (2001) ALK1 and p80 expression and chromosomal rearrangements involving 2p23 in inflammatory myofibroblastic tumor. Mod Pathol 14(6):569\u2013576. https:\/\/doi.org\/10.1038\/modpathol.3880352","journal-title":"Mod Pathol"},{"issue":"15","key":"4545_CR5","doi-asserted-by":"publisher","first-page":"3662","DOI":"10.3390\/cancers14153662","volume":"14","author":"L Gros","year":"2022","unstructured":"Gros L, Dei Tos AP, Jones RL, Digklia A (2022) Inflammatory Myofibroblastic Tumour: State of the Art. Cancers (Basel) 14(15):3662. https:\/\/doi.org\/10.3390\/cancers14153662","journal-title":"Cancers (Basel)"},{"issue":"8","key":"4545_CR6","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.3390\/cancers17081327","volume":"17","author":"JH Choi","year":"2025","unstructured":"Choi JH (2025) Inflammatory myofibroblastic tumor: an updated review. Cancers (Basel) 17(8):1327. https:\/\/doi.org\/10.3390\/cancers17081327","journal-title":"Cancers (Basel)"},{"key":"4545_CR7","doi-asserted-by":"publisher","unstructured":"Sakurai H, Hasegawa T, Watanabe Si, Suzuki K, Asamura H, Tsuchiya R (2004) Inflammatory myofibroblastic tumor of the lung. Eur J Cardiothorac Surg 25(2):155-9. https:\/\/doi.org\/10.1016\/s1010-7940(03)00678-x","DOI":"10.1016\/s1010-7940(03)00678-x"},{"issue":"3","key":"4545_CR8","doi-asserted-by":"publisher","first-page":"266","DOI":"10.4103\/ijri.IJRI_93_20","volume":"30","author":"A Irodi","year":"2020","unstructured":"Irodi A, Chacko BR, Prajapati A, Prabhu AJ, Vimala LR, Christopher DJ, Gnanamuthu BR (2020) Inflammatory myofibroblastic tumours of the thorax: Radiologic and clinicopathological correlation. Indian J Radiol Imaging 30(3):266\u2013272. https:\/\/doi.org\/10.4103\/ijri.IJRI_93_20","journal-title":"Indian J Radiol Imaging"},{"key":"4545_CR9","doi-asserted-by":"publisher","unstructured":"Huang YL, Hsu CC, Huang DD, Yang JC, Wu SG 2025 Identification of the molecular characterization and tumor microenvironment of thoracic inflammatory myofibroblastic tumors. J Formos Med Assoc. 28:S0929-6646(25)00040\u2009\u2013\u20093. https:\/\/doi.org\/10.1016\/j.jfma.2025.01.024","DOI":"10.1016\/j.jfma.2025.01.024"},{"issue":"5","key":"4545_CR10","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1016\/j.jtho.2018.12.003","volume":"14","author":"JC Chang","year":"2019","unstructured":"Chang JC, Zhang L, Drilon AE, Chi P, Alaggio R, Borsu L, Benayed R, Travis WD, Ladanyi M, Antonescu CR (2019) Expanding the Molecular Characterization of Thoracic Inflammatory Myofibroblastic Tumors beyond ALK Gene Rearrangements. J Thorac Oncol 14(5):825\u2013834","journal-title":"J Thorac Oncol"},{"issue":"12","key":"4545_CR11","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1097\/PAS.0000000000001735","volume":"45","author":"DA Kerr","year":"2021","unstructured":"KerrDA, Thompson LDR, Tafe LJ, Jo VY, Neyaz A, Divakar P, Paydarfar JA, Pastel DA, Shirai K, John I, Seethala RR, Salgado CM, Deshpande V, Bridge JA, Kashofer K, Br\u010di\u0107 I, Linos K (2021) Clinicopathologic and genomic characterization of inflammatory myofibroblastic tumors of the head and neck: highlighting a novel fusion and potential diagnostic pitfall. Am J Surg Pathol 45(12):1707\u20131719. https:\/\/doi.org\/10.1097\/PAS.0000000000001735","journal-title":"Am J Surg Pathol"},{"issue":"4","key":"4545_CR12","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1097\/JTO.0000000000000465","volume":"10","author":"TM Rogers","year":"2015","unstructured":"Rogers TM, Russell PA, Wright G, Wainer Z, Pang JM, Henricksen LA, Singh S, Stanislaw S, Grille J, Roberts E, Solomon B, Fox SB (2015) Comparison of methods in the detection of ALK and ROS1 rearrangements in lung cancer. J Thorac Oncol 10(4):611\u2013618. https:\/\/doi.org\/10.1097\/JTO.0000000000000465","journal-title":"J Thorac Oncol"},{"issue":"8","key":"4545_CR13","doi-asserted-by":"publisher","first-page":"928","DOI":"10.5858\/arpa.2023-0229-OA","volume":"148","author":"R NambirajanA, Sood","year":"2024","unstructured":"NambirajanA,Sood R, Khatoon W, Malik PS, Mohan A, Jain D (2024) Concordance of immunohistochemistry and fluorescence in situ hybridization in the detection of anaplastic lymphoma kinase (ALK) and Ros proto-oncogene 1 (ROS1) gene rearrangements in non-small cell lung carcinoma: a 4.5-year experience highlighting challenges and pitfalls. Arch Pathol Lab Med 148(8):928\u2013937. https:\/\/doi.org\/10.5858\/arpa.2023-0229-OA","journal-title":"Arch Pathol Lab Med"},{"key":"4545_CR14","doi-asserted-by":"publisher","unstructured":"Mittal A, Gupta A, Dhamija E, Barwad A, Rastogi S (2021) Sustained complete response on crizotinib in primary lung inflammatory myofibroblastic tumor - Case report and literature review. Monaldi Arch Chest Dis. 91(3). https:\/\/doi.org\/10.4081\/monaldi.2021.1586","DOI":"10.4081\/monaldi.2021.1586"},{"key":"4545_CR15","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.xjon.2023.12.006","volume":"17","author":"M Vounckx","year":"2023","unstructured":"Vounckx M, Jansen YJL, Fadaei S, Geers C, De Pauw V, Smets D (2023) Unraveling the spectrum of inflammatory myofibroblastic tumors in the lung: A comprehensive case series highlighting endobronchial, pleural, and lung parenchymal tumors. JTCVS Open 17:297\u2013305","journal-title":"JTCVS Open"},{"issue":"1","key":"4545_CR16","first-page":"32","volume":"22","author":"V Leivaditis","year":"2025","unstructured":"Leivaditis V, Baltagianni M, Liolis E, Baltayiannis N, Stanc G, Souka E, Batika P, Grapatsas K, Tchabashvili L, Tasios K, Antzoulas A, Litsas D, Beltsios E, Dahm M, Papatriantafyllou A, Koletsis E, Mulita F (2025) Inflammatory myofibroblastic tumor of the lung: a comprehensive narrative review of clinical and therapeutic insights. Kardiochir Torakochirurgia Pol 22(1):32\u201343","journal-title":"Kardiochir Torakochirurgia Pol"},{"issue":"3","key":"4545_CR17","doi-asserted-by":"publisher","first-page":"598","DOI":"10.21037\/jtd.2017.02.89","volume":"9","author":"L Zhu","year":"2017","unstructured":"Zhu L, Li J, Liu C, Ding W, Lin F, Guo C, Liu L (2017) Pulmonary inflammatory myofibroblastic tumor versus IgG4-related inflammatory pseudotumor: differential diagnosis based on a case series. J Thorac Dis 9(3):598\u2013609","journal-title":"J Thorac Dis"},{"issue":"4","key":"4545_CR18","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1097\/01.pas.0000213393.57322.c7","volume":"31","author":"CM Coffin","year":"2007","unstructured":"Coffin CM, Hornick JL, Fletcher CD (2007) Inflammatory myofibroblastic tumor: comparison of clinicopathologic, histologic, and immunohistochemical features including ALK expression in atypical and aggressive cases. Am J Surg Pathol 31(4):509\u2013520. https:\/\/doi.org\/10.1097\/01.pas.0000213393.57322.c7","journal-title":"Am J Surg Pathol"},{"key":"4545_CR19","doi-asserted-by":"publisher","first-page":"826705","DOI":"10.3389\/fmed.2022.826705","volume":"9","author":"Q Han","year":"2022","unstructured":"Han Q, He X, Cui L, Qiu Y, Li Y, Chen H, Zhang H (2022) Case report: early distant metastatic inflammatory myofibroblastic tumor harboring EML4-ALK fusion gene: study of two typical cases and review of literature. Front Med (Lausanne) 9:826705","journal-title":"Front Med (Lausanne)"},{"issue":"4","key":"4545_CR20","first-page":"158","volume":"23","author":"AK Petridis","year":"2004","unstructured":"Petridis AK, Hempelmann RG, Hugo HH, Eichmann T, Mehdorn HM (2004) Metastatic low-grade inflammatory myofibroblastic tumor (IMT) in the central nervous system of a 29-year-old male patient. Clin Neuropathol 23(4):158\u2013166","journal-title":"Clin Neuropathol"},{"issue":"5","key":"4545_CR21","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1111\/1759-7714.15203","volume":"15","author":"S Sakoda","year":"2024","unstructured":"Sakoda S, Tanaka K, Koga Y, Mikumo H, Tsuchiya-Kawano Y, Harada E, Tamiya S, Okamoto I (2024) A case of inflammatory myofibroblastic tumor harboring EML4-ALK fusion with a brain metastasis responding to alectinib. Thorac Cancer 15(5):415\u2013418. https:\/\/doi.org\/10.1111\/1759-7714.15203","journal-title":"Thorac Cancer"},{"issue":"8","key":"4545_CR22","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1158\/2159-8290.CD-14-0377","volume":"4","author":"CM Lovly","year":"2014","unstructured":"Lovly CM, Gupta A, Lipson D, Otto G, Brennan T, Chung CT, Borinstein SC, Ross JS, Stephens PJ, Miller VA, Coffin CM (2014) Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions. Cancer Discov 4(8):889\u2013895. https:\/\/doi.org\/10.1158\/2159-8290.CD-14-0377","journal-title":"Cancer Discov"},{"issue":"1","key":"4545_CR23","doi-asserted-by":"publisher","first-page":"e15496","DOI":"10.1111\/1759-7714.15496","volume":"16","author":"X Si","year":"2025","unstructured":"Si X, Wu S, Feng R, Wang M, Wang H, Zhang X, Zhang L, Xu K (2025) Clinicopathological Characteristics of Inflammatory Myofibroblastic Tumor: A Single Center Retrospective Cohort Study. Thorac Cancer 16(1):e15496. https:\/\/doi.org\/10.1111\/1759-7714.15496","journal-title":"Thorac Cancer"},{"issue":"10","key":"4545_CR24","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.5858\/arpa.2021-0230-OA","volume":"146","author":"Q Yao","year":"2022","unstructured":"Yao Q, Bai Q, Zhang X, Ji G, Chang H, Cai X, Yu L, Wang J, Zhu X, Zhou X (2022) Assessment of ALK Fusions in Uncommon Inflammatory Myofibroblastic Tumors With ALK IHC Positivity but FISH-Equivocal Findings by Targeted RNA Sequencing. Arch Pathol Lab Med 146(10):1234\u20131242","journal-title":"Arch Pathol Lab Med"},{"issue":"7","key":"4545_CR25","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1097\/PAS.0000000000000404","volume":"39","author":"CR Antonescu","year":"2015","unstructured":"Antonescu CR, Suurmeijer AJ, Zhang L, Sung YS, Jungbluth AA, Travis WD, Al-Ahmadie H, Fletcher CD, Alaggio R (2015) Molecular characterization of inflammatory myofibroblastic tumors with frequent ALK and ROS1 gene fusions and rare novel RET rearrangement. Am J Surg Pathol 39(7):957\u2013967. https:\/\/doi.org\/10.1097\/PAS.0000000000000404","journal-title":"Am J Surg Pathol"},{"issue":"5","key":"4545_CR26","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1038\/modpathol.2014.165","volume":"28","author":"JL Hornick","year":"2015","unstructured":"Hornick JL, Sholl LM, Dal Cin P, Childress MA, Lovly CM (2015) Expression of ROS1 predicts ROS1 gene rearrangement in inflammatory myofibroblastic tumors. Mod Pathol 28(5):732\u2013739. https:\/\/doi.org\/10.1038\/modpathol.2014.165","journal-title":"Mod Pathol"},{"issue":"12","key":"4545_CR27","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1016\/j.jtho.2019.07.005","volume":"14","author":"E Conde","year":"2019","unstructured":"Conde E, Hernandez S, Martinez R, Angulo B, De Castro J, Collazo-Lorduy A, Jimenez B, Muriel A, Mate JL, Moran T, Aranda I, Massuti B, Rojo F, Domine M, Sansano I, Garcia F, Felip E, Manche\u00f1o N, Juan O, Sanz J, Gonzalez-Larriba JL, Atienza-Cuevas L, Arriola-Arellano E, Abdulkader I, Garcia-Gonzalez J, Camacho C, Rodriguez-Abreu D, Teixido C, Reguart N, Gonzalez-Pi\u00f1eiro A, Lazaro-Quintela M, Lozano MD, Gurpide A, Gomez-Roman J, Lopez-Brea M, Pijuan L, Salido M, Arriola E, Company A, Insa A, Esteban-Rodriguez I, Saiz M, Azkona E, Alvarez R, Artal A, Plaza ML, Aguiar D, Enguita AB, Benito A, Paz-Ares L, Garrido P, Lopez-Rios F (2019) Assessment of a New ROS1 Immunohistochemistry Clone (SP384) for the Identification of ROS1 Rearrangements in Patients with Non-Small Cell Lung Carcinoma: the ROSING Study. J Thorac Oncol 14(12):2120\u20132132. https:\/\/doi.org\/10.1016\/j.jtho.2019.07.005","journal-title":"J Thorac Oncol"},{"issue":"1","key":"4545_CR28","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1111\/his.12910","volume":"69","author":"H Yamamoto","year":"2016","unstructured":"Yamamoto H, Yoshida A, Taguchi K, Kohashi K, Hatanaka Y, Yamashita A, Mori D, Oda Y (2016) ALK, ROS1 and NTRK3 gene rearrangements in inflammatory myofibroblastic tumours. Histopathology 69(1):72\u201383. https:\/\/doi.org\/10.1111\/his.12910","journal-title":"Histopathology"},{"issue":"7","key":"4545_CR29","doi-asserted-by":"publisher","first-page":"108388","DOI":"10.1016\/j.ejso.2024.108388","volume":"50","author":"A Raitio","year":"2024","unstructured":"Raitio A, Losty PD (2024) Treatment and outcomes in pediatric inflammatory myofibroblastic tumors - A systematic review of published studies Eur J Surg Oncol 50(7):108388. https:\/\/doi.org\/10.1016\/j.ejso.2024.108388","journal-title":"Eur J Surg Oncol"},{"key":"4545_CR30","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.ejca.2021.07.016","volume":"156","author":"P Sch\u00f6ffski","year":"2021","unstructured":"Sch\u00f6ffski P, Kubickova M, Wozniak A, Blay JY, Strauss SJ, Stacchiotti S, Switaj T, B\u00fccklein V, Leahy MG, Italiano A, Isambert N, Debiec-Rychter M, Sciot R, Lee CJ, Speetjens FM, Nzokirantevye A, Neven A, Kasper B (2021) Long-term efficacy update of crizotinib in patients with advanced, inoperable inflammatory myofibroblastic tumour from EORTC trial 90101 CREATE. Eur J Cancer 156:12\u201323","journal-title":"Eur J Cancer"},{"key":"4545_CR31","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.lungcan.2018.12.016","volume":"128","author":"S Mai","year":"2019","unstructured":"Mai S, Xiong G, Diao D, Wang W, Zhou Y, Cai R (2019) Case report: Crizotinib is effective in a patient with ROS1-rearranged pulmonary inflammatory myofibroblastic tumor. Lung Cancer 128:101\u2013104","journal-title":"Lung Cancer"}],"container-title":["Virchows Archiv"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-026-04545-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00428-026-04545-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00428-026-04545-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T18:02:36Z","timestamp":1784052156000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00428-026-04545-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,2]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["4545"],"URL":"https:\/\/doi.org\/10.1007\/s00428-026-04545-8","relation":{},"ISSN":["0945-6317","1432-2307"],"issn-type":[{"value":"0945-6317","type":"print"},{"value":"1432-2307","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,2]]},"assertion":[{"value":"20 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 May 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This retrospective audit was conducted in accordance with the ethical standards of the institutional research committee and the Declaration of Helsinki (2013 revision). Approval was obtained from the Institutional Ethics Committee (Approval No.: IEC-404\/02.09.2016). As this was a retrospective audit of anonymized patient data with no direct patient contact or intervention, the requirement for informed consent was waived by the Institutional Ethics Committee.","order":1,"name":"Ethics","label":"Compliance with Ethical standards","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This work was presented as a poster in European Respiratory Society (ERS) Congress 2025 and has been published as an abstract.","order":2,"name":"Ethics","label":"Disclosure","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":3,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}