{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T07:07:14Z","timestamp":1791443234988,"version":"4.3.3"},"reference-count":110,"publisher":"Springer Science and Business Media LLC","issue":"5-6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Struct Funct"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1007\/s00429-010-0254-0","type":"journal-article","created":{"date-parts":[[2010,5,28]],"date-time":"2010-05-28T03:04:45Z","timestamp":1275015885000},"page":"495-517","source":"Crossref","is-referenced-by-count":353,"title":["The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans"],"prefix":"10.1007","volume":"214","author":[{"given":"John M.","family":"Allman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole A.","family":"Tetreault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atiya Y.","family":"Hakeem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kebreten F.","family":"Manaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katerina","family":"Semendeferi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph M.","family":"Erwin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soyoung","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Goubert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick R.","family":"Hof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,5,29]]},"reference":[{"key":"254_CR1","volume-title":"Evolving brains","author":"JM Allman","year":"2000","unstructured":"Allman JM (2000) Evolving brains. Scientific American Library-W.H.Freeman, New York"},{"key":"254_CR2","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1073\/pnas.90.1.118","volume":"90","author":"J Allman","year":"1993","unstructured":"Allman J, McLaughlin T, Hakeem A (1993) Brain weight and life-span in primate species. Proc Natl Acad Sci USA 90:118\u2013122","journal-title":"Proc Natl Acad Sci USA"},{"key":"254_CR3","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1749-6632.2001.tb03476.x","volume":"935","author":"JM Allman","year":"2001","unstructured":"Allman JM, Hakeem A, Erwin JM, Nimchinsky E, Hof P (2001) Anterior cingulate cortex: the evolution of an interface between emotion and cognition. Ann NY Acad Sci 935:107\u2013117","journal-title":"Ann NY Acad Sci"},{"key":"254_CR4","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1177\/107385840200800409","volume":"8","author":"J Allman","year":"2002","unstructured":"Allman J, Hakeem A, Watson K (2002) Two phylogenetic specializations in the human brain. Neuroscientist 8:335\u2013346","journal-title":"Neuroscientist"},{"key":"254_CR5","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.tics.2005.06.008","volume":"9","author":"J Allman","year":"2005","unstructured":"Allman J, Watson K, Tetreault N, Hakeem A (2005) Intuition and autism: a possible role for von Economo neurons. Trends Cogn Sci 9:367\u2013373","journal-title":"Trends Cogn Sci"},{"key":"254_CR6","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1002\/hbm.20554","volume":"30","author":"L Aziz-Zadeh","year":"2009","unstructured":"Aziz-Zadeh L, Kaplan J, Iocoboni M (2009) \u201cAha\u201d: the neural correlates of verbal insight solutions. Hum Brain Mapp 30:908\u2013916","journal-title":"Hum Brain Mapp"},{"key":"254_CR7","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1002\/ajpa.20684","volume":"134","author":"N Barger","year":"2007","unstructured":"Barger N, Stefanacci L, Semendeferi K (2007) A comparative volumetric analysis of the amygdaloid complex and basolateral division in the human and ape brain. Am J Phys Anthropol 134:392\u2013403","journal-title":"Am J Phys Anthropol"},{"key":"254_CR8","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1046\/j.1460-9568.1999.00621.x","volume":"11","author":"S Baron-Cohen","year":"1999","unstructured":"Baron-Cohen S, Ring HA, Wheelwright S, Bullmore ET, Brammer MJ, Simmons A, Williams SC (1999) Social intelligence in the normal and autistic brain: an fMRI study. Eur J Neurosci 11:1891\u20131898","journal-title":"Eur J Neurosci"},{"key":"254_CR9","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.neuroimage.2003.11.003","volume":"21","author":"A Bartels","year":"2004","unstructured":"Bartels A, Zeki S (2004) The neural correlates of maternal and romantic love. Neuroimage 21:1155\u20131166","journal-title":"Neuroimage"},{"key":"254_CR10","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1126\/science.1157632","volume":"321","author":"AH Bass","year":"2008","unstructured":"Bass AH, Gilland EH, Baker R (2008) Evolutionary origins for social vocalization in a vertebrate hindbrain-spinal compartment. Science 321:417\u2013421","journal-title":"Science"},{"key":"254_CR11","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1093\/brain\/awf190","volume":"125","author":"S Berthoz","year":"2002","unstructured":"Berthoz S, Armony JL, Blair RJR, Dolan RJ (2002) An fMRI study of intentional and unintentional (embarrassing) violations of social norms. Brain 125:1696\u20131708","journal-title":"Brain"},{"key":"254_CR12","unstructured":"Betz W (1881) Ueber die feinere Structur der Gehirnrinde des Menschen. Zentralbl Med Wiss 19:193\u2013195, 209\u2013213, 231\u2013234"},{"key":"254_CR13","volume-title":"Catalogue of mammalian brains","author":"K Brauer","year":"1970","unstructured":"Brauer K, Schober W (1970) Catalogue of mammalian brains. VEB Gustav Fischer Verlag, Jena"},{"key":"254_CR14","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/cne.22055","volume":"515","author":"C Butti","year":"2009","unstructured":"Butti C, Sherwood CC, Hakeem AY, Allman JM, Hof PR (2009) Total number and volume of Von Economo neurons in the cerebral cortex of cetaceans. J Comp Neurol 515:243\u2013259","journal-title":"J Comp Neurol"},{"key":"254_CR15","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/sj.mp.4002106","volume":"13","author":"JE Chubb","year":"2008","unstructured":"Chubb JE, Bradshaw NJ, Soares DC, Porteous DJ, Millar JK (2008) The DISC locus in psychiatric illness. Mol Psychiatry 13:36\u201364","journal-title":"Mol Psychiatry"},{"key":"254_CR16","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0166-2236(03)00123-1","volume":"26","author":"AD Craig","year":"2003","unstructured":"Craig AD (2003) A new view of pain as a homeostasis emotion. Trends Neurosci 26:303\u2013307","journal-title":"Trends Neurosci"},{"key":"254_CR17","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.tics.2005.10.005","volume":"912","author":"AD Craig","year":"2005","unstructured":"Craig AD (2005) Forebrain emotional asymmetry: a neuroanatomical basis? Trends Cogn Sci 912:566\u2013571","journal-title":"Trends Cogn Sci"},{"key":"254_CR18","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nrn2555","volume":"10","author":"AD Craig","year":"2009","unstructured":"Craig AD (2009) How do you feel\u2014now? The anterior insula and human awareness. Nat Rev Neurosci 10:59\u201370","journal-title":"Nat Rev Neurosci"},{"key":"254_CR19","doi-asserted-by":"crossref","unstructured":"Craig AD (2010) The sentient self. Brain Struct Funct. doi: 10.1007\/s00429-010-0248-y","DOI":"10.1007\/s00429-010-0248-y"},{"key":"254_CR20","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.1098\/rspb.2007.0876","volume":"274","author":"B Crespi","year":"2007","unstructured":"Crespi B, Summers K, Dorus S (2007) Adaptive evolution of genes underlying schizophrenia. Proc Roy Soc B 274:2801\u20132810","journal-title":"Proc Roy Soc B"},{"key":"254_CR21","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1523\/JNEUROSCI.20-08-03033.2000","volume":"20","author":"HD Critchley","year":"2000","unstructured":"Critchley HD, Elliott R, Mathias CJ, Dolan RJ (2000) Neural activity relating to generation and representation of galvanic skin conductance responses. J Neurosci 20:3033\u20133040","journal-title":"J Neurosci"},{"key":"254_CR22","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0896-6273(01)00225-2","volume":"29","author":"HD Critchley","year":"2001","unstructured":"Critchley HD, Mathias C, Dolan R (2001a) Neural activity in the human brain relating to uncertainty and arousal during anticipation. Neuron 29:537\u2013545","journal-title":"Neuron"},{"key":"254_CR23","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1093\/brain\/124.5.1003","volume":"124","author":"HD Critchley","year":"2001","unstructured":"Critchley HD, Melmed RN, Featherstone E, Mathias CJ, Dolan RJ (2001b) Brain activity during biofeedback relaxation: a functional neuroimaging investigation. Brain 124:1003\u20131012","journal-title":"Brain"},{"key":"254_CR24","doi-asserted-by":"crossref","first-page":"8854","DOI":"10.1523\/JNEUROSCI.1311-05.2005","volume":"28","author":"PL Croxson","year":"2005","unstructured":"Croxson PL, Johansen-Berg H, Behrens TE, Robson MD, Pinsk MA, Gross CG, Richter W, Richter MC, Kastner S, Rushworth MF (2005) Quantitative investigation of connections of the prefrontal cortex in the human and macaque using probabilistic diffusion tractography. J Neurosci 28:8854\u20138866","journal-title":"J Neurosci"},{"key":"254_CR110","unstructured":"Damasio A (1994) Descartes error. Putnam, New York"},{"key":"254_CR25","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1467-9280.1994.tb00630.x","volume":"5","author":"S Dehaene","year":"1994","unstructured":"Dehaene S, Posner MI, Tucker DM (1994) Localization of a neural system for error detection and compensation. Psychol Sci 5:303\u2013305","journal-title":"Psychol Sci"},{"key":"254_CR26","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.biopsych.2008.09.022","volume":"65","author":"A Di Martino","year":"2009","unstructured":"Di Martino A, Ross K, Uddin L, Sklar A, Castellanos F, Milham M (2009) Processes in autism spectrum disorders: an activation likelihood estimation meta-analysis. Biol Psychiatry 65:63\u201374","journal-title":"Biol Psychiatry"},{"key":"254_CR28","doi-asserted-by":"crossref","first-page":"11073","DOI":"10.1073\/pnas.0704320104","volume":"104","author":"NU Dosenbach","year":"2007","unstructured":"Dosenbach NU, Fair DA, Miezin FM, Cohen AL, Wenger KK, Dosenbach RA, Fox MD, Snyder AZ, Vincent JL, Raichle ME, Schlaggar BL, Petersen SE (2007) Distinct brain networks for adaptive and stable task control in humans. Proc Natl Acad Sci USA 104:11073\u201311078","journal-title":"Proc Natl Acad Sci USA"},{"key":"254_CR29","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/j.cell.2007.07.010","volume":"130","author":"X Duan","year":"2007","unstructured":"Duan X, Chang JH, Ge S, Faulkner RL, Kim JY, Kitabatake Y, Liu XB, Yang CH, Jordan JD, Ma DK, Liu CY, Ganesan S, Cheng HJ, Ming GL, Lu B, Song H (2007) Disrupted-in-schizophrenia 1 regulates integration of newly generated neurons in the adult brain. Cell 130:1146\u20131158","journal-title":"Cell"},{"key":"254_CR30","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/ajp.1350090204","volume":"9","author":"BMF Galdikas","year":"1985","unstructured":"Galdikas BMF (1985) Orangutan sociality at Tanjung Puting. Am J Primatol 9:101\u2013119","journal-title":"Am J Primatol"},{"key":"254_CR31","first-page":"57","volume":"19","author":"F Gallyas","year":"1971","unstructured":"Gallyas F (1971) A principle for silver staining of tissue elements by physical development. Acta Morphol Acad Sci 19:57\u201371","journal-title":"Acta Morphol Acad Sci"},{"key":"254_CR32","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1467-9280.1993.tb00586.x","volume":"4","author":"WJ Gehring","year":"1993","unstructured":"Gehring WJ, Goss B, Coles MGH, Meyer DE, Donchin E (1993) A neural system of error detection and compensation. Psychol Sci 4:385\u2013390","journal-title":"Psychol Sci"},{"key":"254_CR33","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1162\/jocn.2006.18.6.932","volume":"18","author":"S Gilbert","year":"2006","unstructured":"Gilbert S, Spengler S, Simons J, Steele J, Lawrie S, Frith C, Burgess P (2006) Functional specialization within rostral prefrontal cortex (Area 10): a meta-analysis. J Cogn Neurosci 18:932\u2013948","journal-title":"J Cogn Neurosci"},{"key":"254_CR34","volume-title":"Developing human brain, growth and epidemiologic neuropathology","author":"FH Gilles","year":"1983","unstructured":"Gilles FH, Leviton A, Dooling EC (1983) Developing human brain, growth and epidemiologic neuropathology. John Wright - PSG Inc, Boston"},{"key":"254_CR35","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1097\/01.PSY.0000097348.45087.96","volume":"66","author":"H G\u00fcndel","year":"2004","unstructured":"G\u00fcndel H, L\u00f3pez-Sala A, Ceballos-Baumann AO, Deus J, Cardoner N, Marten-Mittag B, Soriano-Mas C, Pujol J (2004) Alexithymia correlates with the size of right anterior cingulate. Psychosom Med 66:132\u2013140","journal-title":"Psychosom Med"},{"key":"254_CR36","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1002\/ar.20829","volume":"292","author":"AY Hakeem","year":"2009","unstructured":"Hakeem AY, Sherwood CC, Bonar CJ, Butti C, Hof PR, Allman JM (2009) Von Economo neurons in the elephant brain. Anat Rec (Hoboken) 292:242\u2013248","journal-title":"Anat Rec (Hoboken)"},{"key":"254_CR37","volume-title":"Studien \u00fcber Klinik und Pathologie der Idiotie nebst Untersuchungen \u00fcber die normale Anatomie des Hirnrinde","author":"C Hammarberg","year":"1895","unstructured":"Hammarberg C (1895) Studien \u00fcber Klinik und Pathologie der Idiotie nebst Untersuchungen \u00fcber die normale Anatomie des Hirnrinde. Berling, Uppsala"},{"key":"254_CR38","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1080\/17470910802553508","volume":"4","author":"NA Harrison","year":"2009","unstructured":"Harrison NA, Gray MA, Critchley HD (2009) Dynamic pupillary exchange engages brain regions encoding social salience. Soc Neurosci 4:233\u2013243","journal-title":"Soc Neurosci"},{"key":"254_CR39","doi-asserted-by":"crossref","first-page":"3024","DOI":"10.1093\/hmg\/ddl244","volume":"15","author":"R Hashimoto","year":"2006","unstructured":"Hashimoto R, Numakawa T, Ohnishi T, Kumamaru E, Yagasaki Y, Ishimoto T, Mori T, Nemoto K, Adachi N, Izumi A, Chiba S, Noguchi H, Suzuki T, Iwata N, Ozaki N, Taguchi T, Kamiya A, Kosuga A, Tatsumi M, Kamijima K, Weinberger DR, Sawa A, Kunugi H (2006) Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling. Hum Mol Genet 15:3024\u20133033","journal-title":"Hum Mol Genet"},{"key":"254_CR40","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0304-3940(01)02039-0","volume":"309","author":"M Hayashi","year":"2001","unstructured":"Hayashi M, Ito M, Shimizu K (2001) The spindle neurons are present in the cingulate cortex of chimpanzee fetus. Neurosci Lett 309:97\u2013100","journal-title":"Neurosci Lett"},{"key":"254_CR41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ar.20407","volume":"290","author":"PR Hof","year":"2007","unstructured":"Hof PR, Van der Gucht E (2007) Structure of the cerebral cortex of the humpback whale, Megaptera novaeangliae (Cetacea, Mysticeti, Balaenopteridae). Anat Rec 290:1\u201331","journal-title":"Anat Rec"},{"key":"254_CR42","first-page":"1","volume":"1","author":"O Houd\u00e9","year":"2010","unstructured":"Houd\u00e9 O, Rossi S, Lubin A, Joliot M (2010) Mapping numerical processing, reading, and executive functions in the developing brain: an fMRI meta-analysis of 52 studies including 842 children. Dev Sci 1:1\u201310","journal-title":"Dev Sci"},{"key":"254_CR43","doi-asserted-by":"crossref","first-page":"e2939","DOI":"10.1371\/journal.pone.0002939","volume":"8","author":"M Jabbi","year":"2008","unstructured":"Jabbi M, Bastiaansen J, Keysers C (2008) A common anterior insula representation of disgust observation, experience and imagination shows divergent functional connectivity pathways. PLos One 8:e2939","journal-title":"PLos One"},{"key":"254_CR44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1124\/pr.107.07108","volume":"60","author":"RT Jensen","year":"2008","unstructured":"Jensen RT, Battey JF, Spindel ER, BEnya RV (2008) International Union of Pharmacology, LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and disease states. Pharmacol Rev 60:1\u201342","journal-title":"Pharmacol Rev"},{"key":"254_CR45","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s00401-008-0434-7","volume":"116","author":"JA Kaufman","year":"2008","unstructured":"Kaufman JA, Paul LK, Manaye KF, Granstedt AE, Hof PR, Hakeem AY, Allman JM (2008) Selective reduction of Von Economo neuron number in agenesis of the corpus callosum. Acta Neuropathol 116:479\u2013489","journal-title":"Acta Neuropathol"},{"key":"254_CR46","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.bandc.2007.01.007","volume":"64","author":"DP Kennedy","year":"2007","unstructured":"Kennedy DP, Semendeferi K, Courchesne E (2007) No reduction of spindle neuron number in frontoinsular cortex in autism. Brain Cogn 64:124\u2013129","journal-title":"Brain Cogn"},{"key":"254_CR47","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0896-6273(02)00939-X","volume":"36","author":"H Kikyo","year":"2002","unstructured":"Kikyo H, Ohki K (2002) Neural correlates for feeling-of-knowing: an fMRI parametric analysis. Neuron 36:177\u2013186","journal-title":"Neuron"},{"key":"254_CR48","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1016\/j.neuroimage.2006.11.014","volume":"34","author":"TA Klein","year":"2007","unstructured":"Klein TA, Endrass T, Kathmann N, Neumann J, von Cramon DY, Ullsperger M (2007) Neural correlates of error awareness. NeuroImage 34:1774\u20131781","journal-title":"NeuroImage"},{"key":"254_CR49","doi-asserted-by":"crossref","first-page":"20084","DOI":"10.1073\/pnas.0710103104","volume":"104","author":"F Krueger","year":"2007","unstructured":"Krueger F, McCabe K, Moll J, Kriegeskorte N, Zahn R, Strenziok M, Heinecke A, Grafman J (2007) Neural correlates of trust. Proc Natl Acad Sci USA 104:20084\u201320089","journal-title":"Proc Natl Acad Sci USA"},{"key":"254_CR50","doi-asserted-by":"crossref","first-page":"19220","DOI":"10.1073\/pnas.0706190104","volume":"104","author":"Y Kunimatsu","year":"2007","unstructured":"Kunimatsu Y, Nakatsukasa M, Sawada Y, Sakai T, Hyodo M, Hyodo H, Itaya T, Nakaya H, Saegusa H, Mazurier A, Saneyoshi M, Tsujikawa H, Yamamoto A, Mbua E (2007) A new Late Miocene great ape from Kenya and its implications for the origins of African great apes and humans. Proc Natl Acad Sci USA 104:19220\u201319225","journal-title":"Proc Natl Acad Sci USA"},{"key":"254_CR51","doi-asserted-by":"crossref","unstructured":"Lamm C, Singer T (2010) Role of anterior insular cortex in social emotions. Brain Struct Funct. doi: 10.1007\/s00429-010-0251-3","DOI":"10.1007\/s00429-010-0251-3"},{"key":"254_CR52","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.yhbeh.2006.06.028","volume":"50","author":"M Lim","year":"2006","unstructured":"Lim M, Young L (2006) Neuropeptidergic regulation of affiliative behavior and social bonding in animals. Horm Behav 50:506\u2013517","journal-title":"Horm Behav"},{"key":"254_CR53","doi-asserted-by":"crossref","first-page":"e883","DOI":"10.1371\/journal.pone.0000883","volume":"2","author":"MV Lombardo","year":"2007","unstructured":"Lombardo MV, Barnes JL, Wheelwright SJ, Baron-Cohen S (2007) Self-referential cognition and empathy in autism. PLoS One 2:e883","journal-title":"PLoS One"},{"key":"254_CR54","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0006-3223(01)01284-7","volume":"51","author":"JP Lorberbaum","year":"2002","unstructured":"Lorberbaum JP, Newman JD, Horwitz AR, Dubno JR, Lydiard RB, Hamner MB, Bohning DE, George MS (2002) A potential role for thalamocingulate circuitry in human maternal behavior. Biol Psychiatry 51:431\u2013445","journal-title":"Biol Psychiatry"},{"key":"254_CR55","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/scientificamerican0709-60","volume":"301","author":"PF MacNeilage","year":"2009","unstructured":"MacNeilage PF, Rogers LJ, Vallortigara G (2009) Origins of the left & right brain. Sci Am 301:60\u201367","journal-title":"Sci Am"},{"key":"254_CR56","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0165-0270(83)90086-9","volume":"9","author":"B Merker","year":"1983","unstructured":"Merker B (1983) Silver staining of cell bodies by means of physical development. J Neurosci Methods 9:235\u2013241","journal-title":"J Neurosci Methods"},{"key":"254_CR57","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0003-3472(05)80603-7","volume":"42","author":"JC Mitani","year":"1991","unstructured":"Mitani JC, Grether GF, Rodman PS, Priatna D (1991) Associations among wild orangutans: sociality, passive aggregations or chance? Anim Behav 42:33\u201346","journal-title":"Anim Behav"},{"key":"254_CR58","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.neulet.2009.03.101","volume":"457","author":"I Mutschler","year":"2009","unstructured":"Mutschler I, Wieckhorst B, Kowalevski S, Derix J, Wentlandt J, Schulze-Bonhage A, Ball T (2009) Functional organization of the human interior insular cortex. Neurosci Lett 457:66\u201370","journal-title":"Neurosci Lett"},{"key":"254_CR59","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.tins.2008.09.009","volume":"32","author":"NH Naqvi","year":"2009","unstructured":"Naqvi NH, Bechara A (2009) The hidden island of addiction: the insula. Trends Neurosci 32:56\u201367","journal-title":"Trends Neurosci"},{"key":"254_CR27","doi-asserted-by":"crossref","unstructured":"Nelson S, Dosenbach, N, Cohen, A, Schlaggar B, Petersen S (2010) Role of the anterior insula in task-level control and focal attention. Brain Struct Funct. doi: 10.1007\/s00429-010-0260-2","DOI":"10.1007\/s00429-010-0260-2"},{"key":"254_CR60","first-page":"671","volume":"44","author":"G Ngowyang","year":"1932","unstructured":"Ngowyang G (1932) Beschreibung einer Art von Spezialzellen in der Inselrinde - zugleich Bemerkungen \u00fcber die v. Economoschen Spezialzellen. J Psychol Neurol 44:671\u2013674","journal-title":"J Psychol Neurol"},{"key":"254_CR61","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/cne.903550106","volume":"355","author":"EA Nimchinsky","year":"1995","unstructured":"Nimchinsky EA, Vogt BA, Morrison JH, Hof PR (1995) Spindle neurons of the human anterior cingulate cortex. J Comp Neurol 355:27\u201337","journal-title":"J Comp Neurol"},{"key":"254_CR62","doi-asserted-by":"crossref","first-page":"5268","DOI":"10.1073\/pnas.96.9.5268","volume":"96","author":"E Nimchinsky","year":"1999","unstructured":"Nimchinsky E, Gilissen E, Allman J, Perl D, Erwin J, Hof P (1999) A neuronal morphologic type unique to humans and great apes. Proc Nat Acad Sci USA 96:5268\u20135273","journal-title":"Proc Nat Acad Sci USA"},{"key":"254_CR63","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4612-1302-4","volume-title":"The behavioral neuroscience of the septal region","author":"R Numan","year":"2000","unstructured":"Numan R (2000) The behavioral neuroscience of the septal region. Springer, New York"},{"key":"254_CR64","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1212\/WNL.42.9.1727","volume":"42","author":"SM Oppenheimer","year":"1992","unstructured":"Oppenheimer SM, Gelb A, Girvin JP, Hachinski VC (1992) Cardiovascular effects of human insular cortex stimulation. Neurology 42:1727\u20131732","journal-title":"Neurology"},{"key":"254_CR65","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/0-306-47461-1_15","volume-title":"All apes great and small","author":"F Patterson","year":"2002","unstructured":"Patterson F, Gordon W (2002) Twenty-seven years of Project Koko and Michael. In: Galdikas B, Briggs N, Sheeran L, Shapiro G, Goodall J (eds) All apes great and small, vol I. Kluwer Press, New York, pp 165\u2013176"},{"key":"254_CR66","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/nrn2107","volume":"8","author":"LK Paul","year":"2007","unstructured":"Paul LK, Brown WS, Adolphs R, Tyszka JM, Richards LJ, Mukherjee P, Sherr EH (2007) Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity. Nat Rev Neurosci 8:287\u2013299","journal-title":"Nat Rev Neurosci"},{"key":"254_CR67","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/39051","volume":"389","author":"ML Phillips","year":"1997","unstructured":"Phillips ML, Young AW, Senior C, Brammer M, Andrew C, Calder AJ, Bullmore ET, Perrett DI, Rowland D, Williams SC, Gray JA, David AS (1997) A specific neural substrate for perceiving facial expressions of disgust. Nature 389:495\u2013498","journal-title":"Nature"},{"key":"254_CR68","doi-asserted-by":"crossref","first-page":"11012","DOI":"10.1523\/JNEUROSCI.3522-07.2007","volume":"27","author":"E Ploran","year":"2007","unstructured":"Ploran E, Nelson S, Velanova K, Petersem S, Wheeler M (2007) Evidence accumulation and moment of recognition: dissociating perceptual recognition processes using fMRI. J Neurosci 27:11012\u201311924","journal-title":"J Neurosci"},{"key":"254_CR69","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1523\/JNEUROSCI.4286-07.2008","volume":"28","author":"K Preuschhoff","year":"2008","unstructured":"Preuschhoff K, Quartz S, Bossaerts P (2008) Human insula activation reflects risk prediction errors as well as risk. J Neurosci 28:2745\u20132752","journal-title":"J Neurosci"},{"key":"254_CR70","volume-title":"Textura del Sistema Nervioso del Hombre y de los Vertebrados, Tomo II","author":"S Ram\u00f3n y Cajal","year":"1899","unstructured":"Ram\u00f3n y Cajal S (1899) Textura del Sistema Nervioso del Hombre y de los Vertebrados, Tomo II. Nicol\u00e1s Moya, Madrid"},{"key":"254_CR71","doi-asserted-by":"crossref","first-page":"2945","DOI":"10.1093\/brain\/awl254","volume":"129","author":"KP Rankin","year":"2006","unstructured":"Rankin KP, Gorno-Tempini ML, Allison SC, Stanley CM, Glenn S, Weiner MW, Miller BL (2006) Structural anatomy of empathy in neurodegenerative disease. Brain 129:2945\u20132956","journal-title":"Brain"},{"key":"254_CR72","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/j.neuropsychologia.2007.11.033","volume":"46","author":"J Rilling","year":"2008","unstructured":"Rilling J, Goldsmith D, Glenn A, Jairam M, Elfenbein H, Dagenais J, Murdock C, Pagnoni (2008) Neural correlates of the affective response to unreciprocated cooperation. Neuropsychologia 46:1265\u20131266","journal-title":"Neuropsychologia"},{"key":"254_CR73","doi-asserted-by":"crossref","DOI":"10.1017\/CBO9780511546372","volume-title":"Comparative vertebrate lateralization","author":"L Rogers","year":"2002","unstructured":"Rogers L, Andrew R (2002) Comparative vertebrate lateralization. Cambridge University Press, Cambridge"},{"key":"254_CR74","first-page":"5","volume":"35","author":"M Rose","year":"1927","unstructured":"Rose M (1927) Gyrus limbicus anterior und Regio retrosplenialis (Cortex holoprotoptychos quinquestratificatus) - Vergleichende Architektonik bei Tier und Menschen. J Psychol Neurol 35:5\u2013217","journal-title":"J Psychol Neurol"},{"key":"254_CR75","first-page":"467","volume":"37","author":"M Rose","year":"1928","unstructured":"Rose M (1928) Die Inselrinde des Menschen und der Tiere. J Psychol Neurol 37:467\u2013624","journal-title":"J Psychol Neurol"},{"key":"254_CR76","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1126\/science.1082976","volume":"300","author":"AG Sanfey","year":"2003","unstructured":"Sanfey AG, Rilling RJ, Aronson JA, Nystrom LE, Cohen JD (2003) The neural basis of economic decision-making in the ultimatum game. Science 300:1755\u20131758","journal-title":"Science"},{"key":"254_CR77","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.jhevol.2005.06.004","volume":"49","author":"NM Schenker","year":"2005","unstructured":"Schenker NM, Desgouttes A, Semendeferi K (2005) Neural connectivity and cortical substrates of cognition in hominoids. J Hum Evol 49:547\u2013569","journal-title":"J Hum Evol"},{"key":"254_CR78","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1097\/WCO.0b013e3283168e2d","volume":"21","author":"WW Seeley","year":"2008","unstructured":"Seeley WW (2008) Selective functional, regional, and neuronal vulnerability in frontotemporal dementia. Curr Opin Neurol 21:701\u2013707","journal-title":"Curr Opin Neurol"},{"key":"254_CR79","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1002\/ana.21055","volume":"60","author":"WW Seeley","year":"2006","unstructured":"Seeley WW, Carlin DA, Allman JM, Macedo MN, Bush C, Miller BL, Dearmond SJ (2006) Early frontotemporal dementia targets neurons unique to apes and humans. Ann Neurol 60:660\u2013667","journal-title":"Ann Neurol"},{"key":"254_CR80","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1097\/WAD.0b013e31815c0f14","volume":"21","author":"WW Seeley","year":"2007","unstructured":"Seeley WW, Allman JM, Carlin DA, Crawford RK, Macedo MN, Greicius MD, Dearmond SJ, Miller BL (2007) Divergent social functioning in behavioral variant frontotemporal dementia and Alzheimer disease: reciprocal networks and neuronal evolution. Alzheimer Dis Assoc Disord 21:S50\u2013S57","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"254_CR81","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/(SICI)1096-8644(199806)106:2<129::AID-AJPA3>3.0.CO;2-L","volume":"106","author":"K Semendeferi","year":"1998","unstructured":"Semendeferi K, Armstrong E, Schleicher A, Zilles K, Van Hoesen GW (1998) Limbic frontal cortex in hominoids: a comparative study of area 13. Am J Phys Anthropol 106:129\u2013155","journal-title":"Am J Phys Anthropol"},{"key":"254_CR82","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1001\/archgenpsychiatry.2009.103","volume":"66","author":"P Shaw","year":"2009","unstructured":"Shaw P, Lalonde F, Lepage C, Rabin C, Eckstrand K, Sharp W, Greenstein D, Evans A, Giedd JM, Rapoport J (2009) Development of cortical asymmetry in typically developing children and its disruption in attention-deficit\/hyperactivity disorder. Arch Gen Psychiatry 66:888\u2013896","journal-title":"Arch Gen Psychiatry"},{"key":"254_CR83","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1159\/000075673","volume":"63","author":"CC Sherwood","year":"2004","unstructured":"Sherwood CC, Holloway RL, Erwin JM, Hof PR (2004) Cortical orofacial motor representation in Old World monkeys, great apes, and humans. II: stereologic analysis of chemoarchitecture. Brain Behav Evol 63:82\u2013106","journal-title":"Brain Behav Evol"},{"key":"254_CR84","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1002\/cne.21399","volume":"503","author":"CC Sherwood","year":"2007","unstructured":"Sherwood CC, Wahl E, Erwin JM, Hof PR, Hopkins WD (2007) Histological asymmetries of primary motor cortex predict handedness in chimpanzees. J Comp Neurol 503:525\u2013537","journal-title":"J Comp Neurol"},{"key":"254_CR85","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0006-3223(00)00251-1","volume":"48","author":"LM Shin","year":"2000","unstructured":"Shin LM, Dougherty DD, Orr SP, Pitman RK, Lasko M, Macklin ML, Alpert NM, Fischman AJ, Rauch SL (2000) Activation of anterior paralimbic structures during guilt-related script-driven imagery. Biol Psychiatry 48:43\u201350","journal-title":"Biol Psychiatry"},{"key":"254_CR86","doi-asserted-by":"crossref","DOI":"10.1002\/9780470753286","volume-title":"Handbook of epilepsy treatment","author":"S Shorvon","year":"2005","unstructured":"Shorvon S (2005) Handbook of epilepsy treatment. Wiley, New York"},{"key":"254_CR87","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s00401-009-0568-2","volume":"118","author":"ML Simms","year":"2009","unstructured":"Simms ML, Kemper TL, Timbie CM, Bauman ML, Blatt GJ (2009) The anterior cingulate cortex in autism: heterogeneity of qualitative and quantitative cytoarchitectonic features suggests possible subgroups. Acta Neuropathol 118:673\u2013684","journal-title":"Acta Neuropathol"},{"key":"254_CR88","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1126\/science.1093535","volume":"303","author":"T Singer","year":"2004","unstructured":"Singer T, Seymour B, O\u2019Doherty J, Kaube H, Dolan RJ, Frith CD (2004a) Empathy for pain involves the affective but not sensory components of pain. Science 303:1157\u20131162","journal-title":"Science"},{"key":"254_CR89","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S0896-6273(04)00014-5","volume":"41","author":"T Singer","year":"2004","unstructured":"Singer T, Kiebel SJ, Winston JS, Dolan RJ, Frith CD (2004b) Brain responses to the acquired moral status of faces. Neuron 41:653\u2013662","journal-title":"Neuron"},{"key":"254_CR90","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000060415","volume":"73","author":"I Singleton","year":"2002","unstructured":"Singleton I, van Schaik CP (2002) The social organisation of a population of Sumatran orangutans. Folia Primatol 73:1\u201320","journal-title":"Folia Primatol"},{"key":"254_CR91","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.1097\/00001756-200109170-00019","volume":"12","author":"SA Spence","year":"2001","unstructured":"Spence SA, Farrow TF, Herford AE, Wilkinson ID, Zheng Y, Woodruff PW (2001) Behavioural and functional anatomical correlates of deception in humans. NeuroReport 12:2849\u20132853","journal-title":"NeuroReport"},{"key":"254_CR92","doi-asserted-by":"crossref","first-page":"12569","DOI":"10.1073\/pnas.0800005105","volume":"105","author":"D Sridharan","year":"2008","unstructured":"Sridharan D, Levitin DJ, Menon V (2008) A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks. Proc Natl Acad Sci USA 105:12569\u201312574","journal-title":"Proc Natl Acad Sci USA"},{"key":"254_CR93","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000155963","volume":"35","author":"H Stephan","year":"1981","unstructured":"Stephan H, Frahm HD, Baron G (1981) New and revised data on volumes of brain structures in insectivores and primates. Folia Primatol 35:1\u201329","journal-title":"Folia Primatol"},{"key":"254_CR94","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1016\/j.cub.2005.08.069","volume":"15","author":"G Szebenyi","year":"2005","unstructured":"Szebenyi G, Bollati F, Bisbal M, Sheridan S, Faas L, Wray R, Haferkamp S, Nguyen S, Caceres A, Brady S (2005) Activity-driven dendritic remodeling requires microtubule-associated Protein 1a. Curr Biol 15:1820\u20131826","journal-title":"Curr Biol"},{"key":"254_CR95","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0010-9452(08)70155-2","volume":"40","author":"M Ullsperger","year":"2004","unstructured":"Ullsperger M, von Cramon DY (2004) Neuroimaging of performance monitoring: error detection and beyond. Cortex 40:593\u2013604","journal-title":"Cortex"},{"key":"254_CR96","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/S0010-9452(08)70401-5","volume":"42","author":"H Uylings","year":"2006","unstructured":"Uylings H, Jacosen A, Zilles K, Amunts K (2006) Left-right asymmetry in volume and number of neurons in adult Broca\u2019s area. Cortex 42:652\u2013658","journal-title":"Cortex"},{"key":"254_CR97","unstructured":"van Kooten (2008) Autism counts. Dissertation, Maastricht University"},{"key":"254_CR98","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1007\/BF02970950","volume":"100","author":"C Economo von","year":"1926","unstructured":"von Economo C (1926) Eine neue Art Spezialzellen des Lobus cinguli und Lobus insulae. Zschr ges Neurol Psychiat 100:706\u2013712","journal-title":"Zschr ges Neurol Psychiat"},{"key":"254_CR99","volume-title":"Cellular structure of the human cerebral cortex","author":"C Economo Von","year":"2009","unstructured":"Von Economo C (2009) Cellular structure of the human cerebral cortex. Translated by L.C. Triarhou, Karger, Basel"},{"key":"254_CR100","volume-title":"Die Cytoarchitectonik der Hirnrinde des erwachsenen Menschen","author":"C Economo Von","year":"1925","unstructured":"Von Economo C, Koskinas G (1925) Die Cytoarchitectonik der Hirnrinde des erwachsenen Menschen. Springer, Berlin"},{"key":"254_CR101","doi-asserted-by":"crossref","first-page":"4047","DOI":"10.1523\/JNEUROSCI.5559-05.2008","volume":"28","author":"SS Wang","year":"2008","unstructured":"Wang SS, Shultz JR, Burish MJ, Harrison KH, Hof PR, Towns LC, Wagers MW, Wyatt KD (2008) Functional trade-offs in white matter axonal scaling. J Neurosci 28:4047\u20134056","journal-title":"J Neurosci"},{"key":"254_CR102","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1093\/cercor\/11.9.868","volume":"11","author":"KE Watkins","year":"2001","unstructured":"Watkins KE, Paus T, Lerch JP, Zijdenbos A, Collins DL, Neelin P, Taylor J, Worsley KJ, Evans AC (2001) Structural asymmetries in human brain: a voxel-based statistical analysis of 142 brains. Cereb Cortex 11:868\u2013877","journal-title":"Cereb Cortex"},{"key":"254_CR103","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.neuroscience.2006.04.084","volume":"141","author":"KK Watson","year":"2006","unstructured":"Watson KK, Jones TK, Allman JM (2006) Dendritic architecture of the von Economo neurons. Neuroscience 141:1107\u20131112","journal-title":"Neuroscience"},{"key":"254_CR104","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1093\/cercor\/bhj149","volume":"17","author":"KK Watson","year":"2007","unstructured":"Watson KK, Matthews BJ, Allman JM (2007) Brain activation during sight gags and language-dependent humor. Cereb Cortex 17:314\u2013324","journal-title":"Cereb Cortex"},{"key":"254_CR105","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1002\/cne.901110306","volume":"111","author":"WI Welker","year":"1959","unstructured":"Welker WI, Seidenstein S (1959) Somatic sensory representation in the cerebral cortex of the raccoon (Procyon lotor). J Comp Neurol 111:469\u2013501","journal-title":"J Comp Neurol"},{"key":"254_CR106","unstructured":"Williamson P, Allman JM (2010) The human illnesses: neuropsychiatric disorders and the nature of the human brain. Oxford University Press (in press)"},{"key":"254_CR107","first-page":"305","volume-title":"Brain asymmetry","author":"W Wittling","year":"1995","unstructured":"Wittling W (1995) Brain Asymmetry in the control of autonomic-physiological activity. In: Davidson RJ, Hugdahl K (eds) Brain asymmetry. MIT Press, Cambridge, pp 305\u2013356"},{"issue":"4\u20136","key":"254_CR108","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jphysparis.2007.12.003","volume":"101","author":"J Woodward","year":"2007","unstructured":"Woodward J, Allman J (2007) Moral intuition: its neural substrates and normative significance. J Physiol Paris 101(4\u20136):179\u2013202","journal-title":"J Physiol Paris"},{"key":"254_CR109","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1212\/01.wnl.0000277461.06713.23","volume":"69","author":"JD Woolley","year":"2007","unstructured":"Woolley JD, Gorno-Tempini ML, Seeley WW, Rankin K, Lee SS, Matthews BR, Miller BL (2007) Binge eating is associated with right orbitofrontal-insular-striatal atrophy in frontotemporal dementia. Neurology 69:1424\u20131433","journal-title":"Neurology"}],"container-title":["Brain Structure and Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.springerlink.com\/index\/pdf\/10.1007\/s00429-010-0254-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T19:11:01Z","timestamp":1551381061000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00429-010-0254-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,29]]},"references-count":110,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["254"],"URL":"https:\/\/doi.org\/10.1007\/s00429-010-0254-0","relation":{},"ISSN":["1863-2653","1863-2661"],"issn-type":[{"value":"1863-2653","type":"print"},{"value":"1863-2661","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,29]]}}}