{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:22:41Z","timestamp":1772119361484,"version":"3.50.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2020,6,27]],"date-time":"2020-06-27T00:00:00Z","timestamp":1593216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,6,27]],"date-time":"2020-06-27T00:00:00Z","timestamp":1593216000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100011780","name":"Hong Kong Arts Development Council","doi-asserted-by":"crossref","award":["27104616"],"award-info":[{"award-number":["27104616"]}],"id":[{"id":"10.13039\/501100011780","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001675","name":"International Brain Research Organization","doi-asserted-by":"publisher","award":["Exchange Fellowship"],"award-info":[{"award-number":["Exchange Fellowship"]}],"id":[{"id":"10.13039\/501100001675","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Brain Struct Funct"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1007\/s00429-020-02102-w","type":"journal-article","created":{"date-parts":[[2020,6,27]],"date-time":"2020-06-27T16:04:16Z","timestamp":1593273856000},"page":"1957-1966","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Serotonergic treatment normalizes midbrain dopaminergic neuron increase after periaqueductal gray stimulation"],"prefix":"10.1007","volume":"225","author":[{"given":"Shawn Zheng Kai","family":"Tan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasin","family":"Temel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariel Yovela","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea Tsz Ching","family":"Mok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Angelo Udal","family":"Perucho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arjan","family":"Blokland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Aquili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei Ling","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6692-6285","authenticated-orcid":false,"given":"Lee Wei","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,6,27]]},"reference":[{"key":"2102_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2013.11.007.Dopamine","author":"AD Abraham","year":"2014","unstructured":"Abraham AD, Neve KA, Lattal KM (2014) Dopamine and extinction: A convergence of theory with fear and reward circuitry. Neurobiol Learn Mem. https:\/\/doi.org\/10.1016\/j.nlm.2013.11.007.Dopamine","journal-title":"Neurobiol Learn Mem"},{"key":"2102_CR2","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1016\/j.neuropharm.2013.11.024","volume":"79","author":"G Azkona","year":"2014","unstructured":"Azkona G, Sagarduy A, Aristieta A et al (2014) Buspirone anti-dyskinetic effect is correlated with temporal normalization of dysregulated striatal DRD1 signalling in l-DOPA-treated rats. Neuropharmacology 79:726\u2013737. https:\/\/doi.org\/10.1016\/j.neuropharm.2013.11.024","journal-title":"Neuropharmacology"},{"key":"2102_CR3","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1037\/h0026779","volume":"67","author":"RJ Blanchard","year":"1969","unstructured":"Blanchard RJ, Blanchard DC (1969) Crouching as an index of fear. J Comp Physiol Psychol 67:370. https:\/\/doi.org\/10.1037\/h0026779","journal-title":"J Comp Physiol Psychol"},{"key":"2102_CR4","doi-asserted-by":"publisher","first-page":"3309","DOI":"10.1007\/s00213-017-4715-5","volume":"234","author":"CP Di","year":"2017","unstructured":"Di CP, Cormick PM, Stefan C, Wong E (2017) The effects of buspirone on occupancy of dopamine receptors and the rat gambling task. Psychopharmacology 234:3309\u20133320. https:\/\/doi.org\/10.1007\/s00213-017-4715-5","journal-title":"Psychopharmacology"},{"key":"2102_CR5","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1016\/S0893-6080(02)00052-7","volume":"15","author":"ND Daw","year":"2002","unstructured":"Daw ND, Kakade S, Dayan P (2002) Opponent interactions between serotonin and dopamine. Neural Networks 15:603\u2013616","journal-title":"Neural Networks"},{"key":"2102_CR30","doi-asserted-by":"publisher","first-page":"3426","DOI":"10.1523\/JNEUROSCI.18-09-03426.1998","volume":"18","author":"OBM De","year":"1998","unstructured":"De OBM, Decola JP, Maren S, Fanselow MS (1998) Distinct regions of the periaqueductal gray are involved in the acquisition and expression of defensive responses. J Neurosci 18:3426\u20133432","journal-title":"J Neurosci"},{"key":"2102_CR6","first-page":"223","volume":"34","author":"E Dremencov","year":"2009","unstructured":"Dremencov E, El MM, Blier P (2009) Effects of sustained serotonin reuptake inhibition on the firing of dopamine neurons in the rat ventral tegmental area. J Psychiatry Neurosci 34:223\u2013229","journal-title":"J Psychiatry Neurosci"},{"key":"2102_CR7","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1016\/j.neubiorev.2005.03.027","volume":"29","author":"D Eilam","year":"2005","unstructured":"Eilam D (2005) Die hard: A blend of freezing and fleeing as a dynamic defense - Implications for the control of defensive behavior. Neurosci Biobehav Rev 29:1181\u20131191. https:\/\/doi.org\/10.1016\/j.neubiorev.2005.03.027","journal-title":"Neurosci Biobehav Rev"},{"key":"2102_CR8","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/S0079-6123(08)00901-1","volume":"172","author":"E Esposito","year":"2008","unstructured":"Esposito E, Di MV, Di GG et al (2008) Serotonin \u2013 dopamine interaction : an overview. Prog Brain Res 172:3\u20136. https:\/\/doi.org\/10.1016\/S0079-6123(08)00901-1","journal-title":"Prog Brain Res"},{"key":"2102_CR9","doi-asserted-by":"publisher","first-page":"11089","DOI":"10.1523\/JNEUROSCI.1616-09.2009","volume":"29","author":"JP Fadok","year":"2009","unstructured":"Fadok JP, Dickerson TMK, Palmiter RD (2009) Dopamine is necessary for cue-dependent fear conditioning. J Neurosci 29:11089\u201311097. https:\/\/doi.org\/10.1523\/JNEUROSCI.1616-09.2009","journal-title":"J Neurosci"},{"key":"2102_CR10","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1016\/S0079-6123(08)00928-X","volume":"172","author":"A Feria-velasco","year":"2008","unstructured":"Feria-velasco A, Gonza I (2008) Serotonin \/ dopamine interaction in memory formation. Prog Brain Res 172:603\u2013623. https:\/\/doi.org\/10.1016\/S0079-6123(08)00928-X","journal-title":"Prog Brain Res"},{"key":"2102_CR11","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1111\/j.1460-9568.2010.07101.x","volume":"31","author":"C Herry","year":"2010","unstructured":"Herry C, Ferraguti F, Singewald N et al (2010) Neuronal circuits of fear extinction. Eur J Neurosci 31:599\u2013612. https:\/\/doi.org\/10.1111\/j.1460-9568.2010.07101.x","journal-title":"Eur J Neurosci"},{"key":"2102_CR12","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.neuropharm.2006.03.009","volume":"51","author":"S Hogg","year":"2006","unstructured":"Hogg S, Michan L, Jessa M (2006) Prediction of anti-panic properties of escitalopram in the dorsal periaqueductal grey model of panic anxiety. Neuropharmacology 51:141\u2013145. https:\/\/doi.org\/10.1016\/j.neuropharm.2006.03.009","journal-title":"Neuropharmacology"},{"key":"2102_CR13","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1002\/syn.20853","volume":"65","author":"AV Ivanov","year":"2011","unstructured":"Ivanov AV, Konradsson-geuken A (2011) Effects of S-Citalopram, citalopram, and R-citalopram on the firing patterns of dopamine neurons in the ventral tegmental area, N -methyl- D -aspartate receptor-mediated transmission in the medial prefrontal cortex and cognitive function in the rat. Synapse 65:357\u2013367. https:\/\/doi.org\/10.1002\/syn.20853","journal-title":"Synapse"},{"key":"2102_CR14","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.neulet.2010.02.038","volume":"473","author":"A Jahanshahi","year":"2010","unstructured":"Jahanshahi A, Wei L, Steinbusch HWM et al (2010) Neuroscience Letters Buspirone-induced changes in the serotonergic and non-serotonergic cells in the dorsal raphe nucleus of rats. Neurosci Lett 473:136\u2013140. https:\/\/doi.org\/10.1016\/j.neulet.2010.02.038","journal-title":"Neurosci Lett"},{"key":"2102_CR15","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/0014-2999(90)90271-7","volume":"177","author":"F Jenck","year":"1990","unstructured":"Jenck F, Broekkamp CLE, Van DAML (1990) The effect of antidepressants on aversive periaqueductal gray stimulation in rats. Eur J Pharmacol 177:201\u2013204","journal-title":"Eur J Pharmacol"},{"key":"2102_CR16","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/S0924-977X(97)00055-2","volume":"8","author":"F Jenck","year":"1998","unstructured":"Jenck F, Moreau J, Berendsen HHG et al (1998) Antiaversive effects of 5HT 2C receptor agonists and fluoxetine in a model of panic-like anxiety in rats. Eur Neuropsychopharmacol 8:161\u2013168","journal-title":"Eur Neuropsychopharmacol"},{"key":"2102_CR17","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/0165-1781(95)02673-K","volume":"57","author":"F Jenck","year":"1995","unstructured":"Jenck F, Moreau J, Martin JR (1995) Dorsal periaqueductal gray-induced aversion as a simulation of panic anxiety : Elements of face and predictive validity. Psychiatry Res 57:181\u2013191","journal-title":"Psychiatry Res"},{"key":"2102_CR18","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.pbb.2008.12.022","volume":"92","author":"N Kakui","year":"2009","unstructured":"Kakui N, Yokoyama F, Yamauchi M et al (2009) Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and \u03b11-adrenergic receptor. Pharmacol Biochem Behav 92:393\u2013398. https:\/\/doi.org\/10.1016\/j.pbb.2008.12.022","journal-title":"Pharmacol Biochem Behav"},{"key":"2102_CR19","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1007\/s007020050079","volume":"105","author":"F Lechin","year":"1998","unstructured":"Lechin F, Van Der DB, Jara H et al (1998) Effects of buspirone on plasma neurotransmitters in healthy subjects. J Neural Transm 105:561\u2013573","journal-title":"J Neural Transm"},{"key":"2102_CR20","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.bbr.2010.12.026","volume":"218","author":"LW Lim","year":"2011","unstructured":"Lim LW, Blokland A, Van DM et al (2011) Increased plasma corticosterone levels after periaqueductal gray stimulation-induced escape reaction or panic attacks in rats. Behav Brain Res 218:301\u2013307. https:\/\/doi.org\/10.1016\/j.bbr.2010.12.026","journal-title":"Behav Brain Res"},{"key":"2102_CR21","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.expneurol.2010.08.035","volume":"226","author":"LW Lim","year":"2010","unstructured":"Lim LW, Blokland A, Tan S et al (2010) Attenuation of fear-like response by escitalopram treatment after electrical stimulation of the midbrain dorsolateral periaqueductal gray. Exp Neurol 226:293\u2013300. https:\/\/doi.org\/10.1016\/j.expneurol.2010.08.035","journal-title":"Exp Neurol"},{"key":"2102_CR22","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.bbr.2008.05.020","volume":"193","author":"LW Lim","year":"2008","unstructured":"Lim LW, Blokland A, Visser-Vandewalle V et al (2008) High-frequency stimulation of the dorsolateral periaqueductal gray and ventromedial hypothalamus fails to inhibit panic-like behaviour. Behav Brain Res 193:197\u2013203. https:\/\/doi.org\/10.1016\/j.bbr.2008.05.020","journal-title":"Behav Brain Res"},{"key":"2102_CR23","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.jchemneu.2009.06.011","volume":"38","author":"LW Lim","year":"2009","unstructured":"Lim LW, Temel Y, Visser-Vandewalle V et al (2009) Fos immunoreactivity in the rat forebrain induced by electrical stimulation of the dorsolateral periaqueductal gray matter. J Chem Neuroanat 38:83\u201396. https:\/\/doi.org\/10.1016\/j.jchemneu.2009.06.011","journal-title":"J Chem Neuroanat"},{"key":"2102_CR24","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.04803","author":"A Liu","year":"2015","unstructured":"Liu A, Jain N, Vyas A, Lim LW (2015) Ventromedial prefrontal cortex stimulation enhances memory and hippocampal neurogenesis in the middle-aged rats. Elife. https:\/\/doi.org\/10.7554\/eLife.04803","journal-title":"Elife"},{"key":"2102_CR25","doi-asserted-by":"publisher","first-page":"329","DOI":"10.3109\/15622970903131597","volume":"11","author":"P Lugenbiel","year":"2010","unstructured":"Lugenbiel P, Sartorius A, Vollmayr B, Schloss P (2010) Creatine transporter expression after antidepressant therapy in rats bred for learned helplessness. World J Biol Psychiatry 11:329\u2013333. https:\/\/doi.org\/10.3109\/15622970903131597","journal-title":"World J Biol Psychiatry"},{"key":"2102_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41467-018-04784-7","volume":"9","author":"R Luo","year":"2018","unstructured":"Luo R, Uematsu A, Weitemier A et al (2018) A dopaminergic switch for fear to safety transitions. Nat Commun 9:1\u201311. https:\/\/doi.org\/10.1038\/s41467-018-04784-7","journal-title":"Nat Commun"},{"key":"2102_CR27","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1002\/syn.20954","volume":"65","author":"L MacGillivray","year":"2011","unstructured":"MacGillivray L, Reynolds KB, Sickand M et al (2011) Inhibition of the serotonin transporter induces microglial activation and downregulation of dopaminergic neurons in the substantia nigra. Synapse 65:1166\u20131172. https:\/\/doi.org\/10.1002\/syn.20954","journal-title":"Synapse"},{"key":"2102_CR28","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1111\/jnc.13649","volume":"139","author":"CC McIntyre","year":"2016","unstructured":"McIntyre CC, Anderson RW (2016) Deep brain stimulation mechanisms: the control of network activity via neurochemistry modulation. J Neurochem 139:338\u2013345. https:\/\/doi.org\/10.1111\/jnc.13649","journal-title":"J Neurochem"},{"key":"2102_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2105-7-123","volume":"7","author":"HJ Motulsky","year":"2006","unstructured":"Motulsky HJ, Brown RE (2006) Detecting outliers when fitting data with nonlinear regression - A new method based on robust nonlinear regression and the false discovery rate. BMC Bioinformatics 7:1\u201320. https:\/\/doi.org\/10.1186\/1471-2105-7-123","journal-title":"BMC Bioinformatics"},{"key":"2102_CR31","unstructured":"Paxinos G, Watson C (2006) The rat brain in stereotaxic coordinates sixth edition by. Acad Press 170:547612. 10.1016\/0143\u20134179(83)90049\u20135"},{"key":"2102_CR32","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.pneurobio.2004.09.004","volume":"74","author":"MA Pezze","year":"2004","unstructured":"Pezze MA, Feldon J (2004) Mesolimbic dopaminergic pathways in fear conditioning. Prog Neurobiol 74:301\u2013320. https:\/\/doi.org\/10.1016\/j.pneurobio.2004.09.004","journal-title":"Prog Neurobiol"},{"key":"2102_CR33","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1016\/j.neuron.2015.04.015","volume":"86","author":"M Pignatelli","year":"2015","unstructured":"Pignatelli M, Bonci A (2015) Review role of dopamine neurons in reward and aversion : a synaptic plasticity perspective. Neuron 86:1145\u20131157. https:\/\/doi.org\/10.1016\/j.neuron.2015.04.015","journal-title":"Neuron"},{"key":"2102_CR34","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.expneurol.2015.12.005","volume":"277","author":"A Sagarduy","year":"2016","unstructured":"Sagarduy A, Llorente J, Miguelez C et al (2016) Buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors. Exp Neurol 277:35\u201345. https:\/\/doi.org\/10.1016\/j.expneurol.2015.12.005","journal-title":"Exp Neurol"},{"key":"2102_CR35","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s00213-002-1364-z","volume":"167","author":"C S\u00e1nchez","year":"2003","unstructured":"S\u00e1nchez C, Bergqvist PBF, Brennum LT et al (2003) Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities. Psychopharmacology 167:353\u2013362. https:\/\/doi.org\/10.1007\/s00213-002-1364-z","journal-title":"Psychopharmacology"},{"key":"2102_CR36","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1007\/s002130100883","volume":"159","author":"LC Schenberg","year":"2002","unstructured":"Schenberg LC, Capucho LB, Vatanabe RO, Vargas LC (2002) Acute effects of clomipramine and fluoxetine on dorsal periaqueductal grey-evoked unconditioned defensive behaviours of the rat. Psychopharmacology 159:138\u2013144. https:\/\/doi.org\/10.1007\/s002130100883","journal-title":"Psychopharmacology"},{"key":"2102_CR37","doi-asserted-by":"publisher","first-page":"127","DOI":"10.5681\/apb.2012.019","volume":"2","author":"H Sharifi","year":"2012","unstructured":"Sharifi H, Nayebi AM, Farajnia S (2012) The effect of chronic administration of buspirone on 6-hydroxydopamine-induced catalepsy in rats. Adv Pharm Bull 2:127\u2013131. https:\/\/doi.org\/10.5681\/apb.2012.019","journal-title":"Adv Pharm Bull"},{"key":"2102_CR38","doi-asserted-by":"crossref","unstructured":"Tan SZK, Poon CH, Chan Y-S, Lim LW (2019a) Deep brain stimulation of the ventromedial prefrontal cortex disrupts consolidation of fear memories. bioRxiv 537514. 10.1101\/537514","DOI":"10.1101\/537514"},{"key":"2102_CR39","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.expneurol.2019.01.004","volume":"314","author":"SZK Tan","year":"2019","unstructured":"Tan SZK, Sheng V, Chan Y-S, Lim LW (2019) Eternal sunshine of the neuromodulated mind: altering fear memories through neuromodulation. Exp Neurol 314:9\u201319","journal-title":"Exp Neurol"},{"key":"2102_CR40","doi-asserted-by":"publisher","first-page":"17087","DOI":"10.1073\/pnas.0704144104","volume":"104","author":"Y Temel","year":"2007","unstructured":"Temel Y, Boothman LJ, Blokland A et al (2007) Inhibition of 5-HT neuron activity and induction of depressive-like behavior by high-frequency stimulation of the subthalamic nucleus. Proc Natl Acad Sci U S A 104:17087\u201317092. https:\/\/doi.org\/10.1073\/pnas.0704144104","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2102_CR41","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1016\/0028-3908(92)90099-B","volume":"31","author":"G Tunnicliff","year":"1992","unstructured":"Tunnicliff G, Brokaw JJ, Hausz JA et al (1992) Influence of repeated treatment with buspirone on central 5-hydroxytryptamine and dopamine synthesis. Neuropharmacology 31:991\u2013995. https:\/\/doi.org\/10.1016\/0028-3908(92)90099-B","journal-title":"Neuropharmacology"},{"key":"2102_CR42","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1037\/0735-7044.111.4.692","volume":"111","author":"DL Walker","year":"1997","unstructured":"Walker DL, Davis M (1997) Involvement of the dorsal periaqueductal gray in the loss of fear-potentiated startle accompanying high footshock training. Behav Neurosci 111:692\u2013702","journal-title":"Behav Neurosci"},{"key":"2102_CR43","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-24277-4","volume-title":"ggplot2: Elegant Graphics for Data Analysis","author":"H Wickham","year":"2016","unstructured":"Wickham H (2016) ggplot2: Elegant Graphics for Data Analysis. Springer-Verlag, New York"},{"key":"2102_CR44","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1097\/01.fbp.0000179280.05654.5a","volume":"16","author":"JM Zanoveli","year":"2005","unstructured":"Zanoveli JM, Nogueira RL, Zangrossi H (2005) Chronic imipramine treatment sensitizes 5-HT1A and 5-HT 2A receptors in the dorsal periaqueductal gray matter: Evidence from the elevated T-maze test of anxiety. Behav Pharmacol 16:543\u2013552. https:\/\/doi.org\/10.1097\/01.fbp.0000179280.05654.5a","journal-title":"Behav Pharmacol"}],"container-title":["Brain Structure and Function"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00429-020-02102-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00429-020-02102-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00429-020-02102-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T19:32:43Z","timestamp":1624735963000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00429-020-02102-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,27]]},"references-count":44,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["2102"],"URL":"https:\/\/doi.org\/10.1007\/s00429-020-02102-w","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/714592","asserted-by":"object"}]},"ISSN":["1863-2653","1863-2661"],"issn-type":[{"value":"1863-2653","type":"print"},{"value":"1863-2661","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,27]]},"assertion":[{"value":"27 September 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 June 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 June 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors declared no biomedical financial interests or potential conflicts of interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All animal works was approved by the Animal Experiments and Ethics Committee of Maastricht University, as well as the Committee on the Use of Live Animals in Teaching and Research (CULATR) of The University of Hong Kong.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical statement"}}]}}