{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T06:38:28Z","timestamp":1792737508084,"version":"4.5.0"},"reference-count":188,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:00:00Z","timestamp":1657843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:00:00Z","timestamp":1657843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100000034","name":"Institute of Neurosciences, Mental Health and Addiction","doi-asserted-by":"publisher","award":["PJT-168855"],"award-info":[{"award-number":["PJT-168855"]}],"id":[{"id":"10.13039\/501100000034","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Brain Struct Funct"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The paraventricular nucleus of the thalamus (PVT) projects to areas of the forebrain involved in regulating behavior. Homeostatic challenges and salient cues activate the PVT and evidence shows that the PVT regulates appetitive and aversive responses. The brainstem is a source of afferents to the PVT and the present study was done to determine if the lateral parabrachial nucleus (LPB) is a relay for inputs to the PVT. Retrograde tracing experiments with cholera toxin B (CTB) demonstrate that the LPB contains more PVT projecting neurons than other regions of the brainstem including the catecholamine cell groups. The hypothesis that the LPB is a relay for signals to the PVT was assessed using an intersectional monosynaptic rabies tracing approach. Sources of inputs to LPB included the reticular formation; periaqueductal gray (PAG); nucleus cuneiformis; and superior and inferior colliculi. Distinctive clusters of input cells to LPB-PVT projecting neurons were also found in the dorsolateral bed nucleus of the stria terminalis (BSTDL) and the lateral central nucleus of the amygdala (CeL). Anterograde viral tracing demonstrates that LPB-PVT neurons densely innervate all regions of the PVT in addition to providing collateral innervation to the preoptic area, lateral hypothalamus, zona incerta and PAG but not the BSTDL and CeL. The paper discusses the anatomical evidence that suggests that the PVT is part of a network of interconnected neurons involved in arousal, homeostasis, and the regulation of behavioral states with forebrain regions potentially providing descending modulation or gating of signals relayed from the LPB to the PVT.<\/jats:p>","DOI":"10.1007\/s00429-022-02534-6","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T04:02:51Z","timestamp":1657857771000},"page":"2409-2437","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Convergence of monosynaptic inputs from neurons in the brainstem and forebrain on parabrachial neurons that project to the paraventricular nucleus of the thalamus"],"prefix":"10.1007","volume":"227","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3632-2189","authenticated-orcid":false,"given":"Gilbert J.","family":"Kirouac","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sa","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuanghong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,7,15]]},"reference":[{"key":"2534_CR1","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S0079-6123(08)62678-3","volume":"85","author":"GE Alexander","year":"1990","unstructured":"Alexander GE, Crutcher MD, DeLong MR (1990) Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, \u201cprefrontal\u201d and \u201climbic\u201d functions. Prog Brain Res 85:119\u2013146","journal-title":"Prog Brain Res"},{"issue":"5","key":"2534_CR2","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1016\/j.conb.2013.04.008","volume":"23","author":"C Alexandre","year":"2013","unstructured":"Alexandre C, Andermann ML, Scammell TE (2013) Control of arousal by the orexin neurons. Curr Opin Neurobiol 23(5):752\u2013759. https:\/\/doi.org\/10.1016\/j.conb.2013.04.008","journal-title":"Curr Opin Neurobiol"},{"key":"2534_CR3","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1111\/j.1749-6632.2003.tb07082.x","volume":"985","author":"GF Alheid","year":"2003","unstructured":"Alheid GF (2003) Extended amygdala and basal forebrain. Ann N Y Acad Sci 985:185\u2013205","journal-title":"Ann N Y Acad Sci"},{"key":"2534_CR4","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1111\/j.1749-6632.1999.tb09294.x","volume":"877","author":"GF Alheid","year":"1999","unstructured":"Alheid GF, Shammah-Lagnado SJ, Beltramino CA (1999) The interstitial nucleus of the posterior limb of the anterior commissure: a novel layer of the central division of extended amygdala. Ann N Y Acad Sci 877:645\u2013654","journal-title":"Ann N Y Acad Sci"},{"key":"2534_CR5","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.neuropharm.2018.11.017","volume":"154","author":"E Arrigoni","year":"2019","unstructured":"Arrigoni E, Chee MJS, Fuller PM (2019) To eat or to sleep: that is a lateral hypothalamic question. Neuropharmacology 154:34\u201349. https:\/\/doi.org\/10.1016\/j.neuropharm.2018.11.017","journal-title":"Neuropharmacology"},{"key":"2534_CR6","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1146\/annurev.neuro.28.061604.135709","volume":"28","author":"G Aston-Jones","year":"2005","unstructured":"Aston-Jones G, Cohen JD (2005) An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance. Annu Rev Neurosci 28:403\u2013450. https:\/\/doi.org\/10.1146\/annurev.neuro.28.061604.135709","journal-title":"Annu Rev Neurosci"},{"issue":"6","key":"2534_CR7","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1016\/j.neuron.2018.10.037","volume":"100","author":"A Barik","year":"2018","unstructured":"Barik A, Thompson JH, Seltzer M, Ghitani N, Chesler AT (2018) A brainstem-spinal circuit controlling nocifensive behavior. Neuron 100(6):1491-1503 e1493. https:\/\/doi.org\/10.1016\/j.neuron.2018.10.037","journal-title":"Neuron"},{"key":"2534_CR8","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2020.598469","volume":"14","author":"JR Barson","year":"2020","unstructured":"Barson JR, Mack NR, Gao WJ (2020) The paraventricular nucleus of the thalamus is an important node in the emotional processing network. Front Behav Neurosci 14:598469. https:\/\/doi.org\/10.3389\/fnbeh.2020.598469","journal-title":"Front Behav Neurosci"},{"issue":"8","key":"2534_CR9","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1093\/chemse\/bjaa059","volume":"45","author":"JJ Bartonjo","year":"2020","unstructured":"Bartonjo JJ, Lundy RF (2020) Distinct populations of amygdala somatostatin-expressing neurons project to the nucleus of the solitary tract and parabrachial nucleus. Chem Senses 45(8):687\u2013698. https:\/\/doi.org\/10.1093\/chemse\/bjaa059","journal-title":"Chem Senses"},{"key":"2534_CR10","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1146\/annurev-vision-102016-061234","volume":"3","author":"MA Basso","year":"2017","unstructured":"Basso MA, May PJ (2017) Circuits for action and cognition: a view from the superior colliculus. Annu Rev Vis Sci 3:197\u2013226. https:\/\/doi.org\/10.1146\/annurev-vision-102016-061234","journal-title":"Annu Rev Vis Sci"},{"issue":"7","key":"2534_CR11","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1038\/s41593-018-0167-4","volume":"21","author":"BS Beas","year":"2018","unstructured":"Beas BS, Wright BJ, Skirzewski M, Leng Y, Hyun JH, Koita O, Ringelberg N, Kwon HB, Buonanno A, Penzo MA (2018) The locus coeruleus drives disinhibition in the midline thalamus via a dopaminergic mechanism. Nat Neurosci 21(7):963\u2013973. https:\/\/doi.org\/10.1038\/s41593-018-0167-4","journal-title":"Nat Neurosci"},{"issue":"6","key":"2534_CR12","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/0301-0082(95)00009-K","volume":"46","author":"MM Behbehani","year":"1995","unstructured":"Behbehani MM (1995) Functional characteristics of the midbrain periaqueductal gray. Prog Neurobiol 46(6):575\u2013605","journal-title":"Prog Neurobiol"},{"key":"2534_CR13","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.jchemneu.2019.05.001","volume":"99","author":"KT Beier","year":"2019","unstructured":"Beier KT (2019) Hitchhiking on the neuronal highway: mechanisms of transsynaptic specificity. J Chem Neuroanat 99:9\u201317. https:\/\/doi.org\/10.1016\/j.jchemneu.2019.05.001","journal-title":"J Chem Neuroanat"},{"issue":"1","key":"2534_CR14","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/0006-8993(89)90449-6","volume":"490","author":"JF Bernard","year":"1989","unstructured":"Bernard JF, Peschanski M, Besson JM (1989) Afferents and efferents of the rat cuneiformis nucleus: an anatomical study with reference to pain transmission. Brain Res 490(1):181\u2013185. https:\/\/doi.org\/10.1016\/0006-8993(89)90449-6","journal-title":"Brain Res"},{"issue":"4","key":"2534_CR15","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/s0149-7634(02)00014-3","volume":"26","author":"HR Berthoud","year":"2002","unstructured":"Berthoud HR (2002) Multiple neural systems controlling food intake and body weight. Neurosci Biobehav Rev 26(4):393\u2013428. https:\/\/doi.org\/10.1016\/s0149-7634(02)00014-3","journal-title":"Neurosci Biobehav Rev"},{"issue":"4","key":"2534_CR16","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1016\/S0306-4522(97)00577-0","volume":"84","author":"S Bhatnagar","year":"1998","unstructured":"Bhatnagar S, Dallman M (1998) Neuroanatomical basis for facilitation of hypothalamic-pituitary-adrenal responses to a novel stressor after chronic stress. Neuroscience 84(4):1025\u20131039","journal-title":"Neuroscience"},{"issue":"1\u20132","key":"2534_CR17","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/S0006-8993(99)02108-3","volume":"851","author":"S Bhatnagar","year":"1999","unstructured":"Bhatnagar S, Dallman MF (1999) The paraventricular nucleus of the thalamus alters rhythms in core temperature and energy balance in a state-dependent manner. Brain Res 851(1\u20132):66\u201375","journal-title":"Brain Res"},{"issue":"14","key":"2534_CR18","doi-asserted-by":"publisher","first-page":"5564","DOI":"10.1523\/JNEUROSCI.20-14-05564.2000","volume":"20","author":"S Bhatnagar","year":"2000","unstructured":"Bhatnagar S, Viau V, Chu A, Soriano L, Meijer OC, Dallman MF (2000) A cholecystokinin-mediated pathway to the paraventricular thalamus is recruited in chronically stressed rats and regulates hypothalamic-pituitary-adrenal function. J Neurosci 20(14):5564\u20135573","journal-title":"J Neurosci"},{"issue":"5","key":"2534_CR19","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1046\/j.0007-1331.2002.00792.x","volume":"14","author":"S Bhatnagar","year":"2002","unstructured":"Bhatnagar S, Huber R, Nowak N, Trotter P (2002) Lesions of the posterior paraventricular thalamus block habituation of hypothalamic-pituitary-adrenal responses to repeated restraint. J Neuroendocrinol 14(5):403\u2013410","journal-title":"J Neuroendocrinol"},{"issue":"2","key":"2534_CR20","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.pbb.2003.08.005","volume":"76","author":"S Bhatnagar","year":"2003","unstructured":"Bhatnagar S, Huber R, Lazar E, Pych L, Vining C (2003) Chronic stress alters behavior in the conditioned defensive burying test: role of the posterior paraventricular thalamus. Pharmacol Biochem Behav 76(2):343\u2013349","journal-title":"Pharmacol Biochem Behav"},{"key":"2534_CR21","volume-title":"The lower brainstem and bodily homeostasis","author":"WW Blessing","year":"1997","unstructured":"Blessing WW (1997) The lower brainstem and bodily homeostasis. Oxford Press, New York"},{"issue":"22","key":"2534_CR22","doi-asserted-by":"publisher","first-page":"6443","DOI":"10.1113\/JP271946","volume":"594","author":"P Bonnavion","year":"2016","unstructured":"Bonnavion P, Mickelsen LE, Fujita A, de Lecea L, Jackson AC (2016) Hubs and spokes of the lateral hypothalamus: cell types, circuits and behaviour. J Physiol 594(22):6443\u20136462. https:\/\/doi.org\/10.1113\/JP271946","journal-title":"J Physiol"},{"key":"2534_CR23","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.59799","author":"AJ Bowen","year":"2020","unstructured":"Bowen AJ, Chen JY, Huang YW, Baertsch NA, Park S, Palmiter RD (2020) Dissociable control of unconditioned responses and associative fear learning by parabrachial CGRP neurons. Elife. https:\/\/doi.org\/10.7554\/eLife.59799","journal-title":"Elife"},{"issue":"3","key":"2534_CR24","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/0149-7634(94)90047-7","volume":"18","author":"ML Brandao","year":"1994","unstructured":"Brandao ML, Cardoso SH, Melo LL, Motta V, Coimbra NC (1994) Neural substrate of defensive behavior in the midbrain tectum. Neurosci Biobehav Rev 18(3):339\u2013346. https:\/\/doi.org\/10.1016\/0149-7634(94)90047-7","journal-title":"Neurosci Biobehav Rev"},{"issue":"1\u20133","key":"2534_CR25","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/s0014-2999(03)01284-6","volume":"463","author":"ML Brandao","year":"2003","unstructured":"Brandao ML, Troncoso AC, de Souza Silva MA, Huston JP (2003) The relevance of neuronal substrates of defense in the midbrain tectum to anxiety and stress: empirical and conceptual considerations. Eur J Pharmacol 463(1\u20133):225\u2013233. https:\/\/doi.org\/10.1016\/s0014-2999(03)01284-6","journal-title":"Eur J Pharmacol"},{"key":"2534_CR26","doi-asserted-by":"publisher","first-page":"98","DOI":"10.3389\/fnana.2017.00098","volume":"11","author":"D Bucci","year":"2017","unstructured":"Bucci D, Busceti CL, Calierno MT, Di Pietro P, Madonna M, Biagioni F, Ryskalin L, Limanaqi F, Nicoletti F, Fornai F (2017) Systematic morphometry of catecholamine nuclei in the brainstem. Front Neuroanat 11:98. https:\/\/doi.org\/10.3389\/fnana.2017.00098","journal-title":"Front Neuroanat"},{"key":"2534_CR27","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.bbr.2013.07.049","volume":"256","author":"G Cabrera","year":"2013","unstructured":"Cabrera G, Cavelli M, Lopez C, Rodriguez-Servetti Z, Vanini G, Chase MH, Falconi A, Torterolo P (2013) Wakefulness-promoting role of the inferior colliculus. Behav Brain Res 256:82\u201394. https:\/\/doi.org\/10.1016\/j.bbr.2013.07.049","journal-title":"Behav Brain Res"},{"issue":"28","key":"2534_CR28","doi-asserted-by":"publisher","first-page":"6340","DOI":"10.1523\/JNEUROSCI.2780-17.2018","volume":"38","author":"YQ Cai","year":"2018","unstructured":"Cai YQ, Wang W, Paulucci-Holthauzen A, Pan ZZ (2018) Brain circuits mediating opposing effects on emotion and pain. J Neurosci 38(28):6340\u20136349. https:\/\/doi.org\/10.1523\/JNEUROSCI.2780-17.2018","journal-title":"J Neurosci"},{"issue":"5","key":"2534_CR29","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1002\/cne.21140","volume":"499","author":"JP Card","year":"2006","unstructured":"Card JP, Sved JC, Craig B, Raizada M, Vazquez J, Sved AF (2006) Efferent projections of rat rostroventrolateral medulla C1 catecholamine neurons: Implications for the central control of cardiovascular regulation. J Comp Neurol 499(5):840\u2013859. https:\/\/doi.org\/10.1002\/cne.21140","journal-title":"J Comp Neurol"},{"issue":"7474","key":"2534_CR30","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1038\/nature12596","volume":"503","author":"ME Carter","year":"2013","unstructured":"Carter ME, Soden ME, Zweifel LS, Palmiter RD (2013) Genetic identification of a neural circuit that suppresses appetite. Nature 503(7474):111\u2013114. https:\/\/doi.org\/10.1038\/nature12596","journal-title":"Nature"},{"key":"2534_CR31","doi-asserted-by":"publisher","first-page":"90","DOI":"10.3389\/fnsys.2015.00090","volume":"9","author":"DC Castro","year":"2015","unstructured":"Castro DC, Cole SL, Berridge KC (2015) Lateral hypothalamus, nucleus accumbens, and ventral pallidum roles in eating and hunger: interactions between homeostatic and reward circuitry. Front Syst Neurosci 9:90. https:\/\/doi.org\/10.3389\/fnsys.2015.00090","journal-title":"Front Syst Neurosci"},{"issue":"1","key":"2534_CR32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0006-8993(90)91570-7","volume":"522","author":"S Chen","year":"1990","unstructured":"Chen S, Su HS (1990) Afferent connections of the thalamic paraventricular and parataenial nuclei in the rat\u2014a retrograde tracing study with iontophoretic application of Fluoro-Gold. Brain Res 522(1):1\u20136","journal-title":"Brain Res"},{"key":"2534_CR33","doi-asserted-by":"publisher","first-page":"202","DOI":"10.3389\/fnmol.2018.00202","volume":"11","author":"J Cheng","year":"2018","unstructured":"Cheng J, Wang J, Ma X, Ullah R, Shen Y, Zhou YD (2018) Anterior paraventricular thalamus to nucleus accumbens projection is involved in feeding behavior in a novel environment. Front Mol Neurosci 11:202. https:\/\/doi.org\/10.3389\/fnmol.2018.00202","journal-title":"Front Mol Neurosci"},{"issue":"42","key":"2534_CR34","doi-asserted-by":"publisher","first-page":"8225","DOI":"10.1523\/JNEUROSCI.1162-19.2019","volume":"39","author":"MC Chiang","year":"2019","unstructured":"Chiang MC, Bowen A, Schier LA, Tupone D, Uddin O, Heinricher MM (2019) Parabrachial complex: a hub for pain and aversion. J Neurosci 39(42):8225\u20138230. https:\/\/doi.org\/10.1523\/JNEUROSCI.1162-19.2019","journal-title":"J Neurosci"},{"issue":"6","key":"2534_CR35","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/j.neuron.2020.03.014","volume":"106","author":"MC Chiang","year":"2020","unstructured":"Chiang MC, Nguyen EK, Canto-Bustos M, Papale AE, Oswald AM, Ross SE (2020) Divergent neural pathways emanating from the lateral parabrachial nucleus mediate distinct components of the pain response. Neuron 106(6):927-939 e925. https:\/\/doi.org\/10.1016\/j.neuron.2020.03.014","journal-title":"Neuron"},{"issue":"11","key":"2534_CR36","doi-asserted-by":"publisher","first-page":"3018","DOI":"10.1523\/JNEUROSCI.3320-16.2017","volume":"37","author":"EA Choi","year":"2017","unstructured":"Choi EA, McNally GP (2017) Paraventricular thalamus balances danger and reward. J Neurosci 37(11):3018\u20133029. https:\/\/doi.org\/10.1523\/JNEUROSCI.3320-16.2017","journal-title":"J Neurosci"},{"issue":"25","key":"2534_CR37","doi-asserted-by":"publisher","first-page":"4945","DOI":"10.1523\/JNEUROSCI.2480-18.2019","volume":"39","author":"EA Choi","year":"2019","unstructured":"Choi EA, Jean-Richard-Dit-Bressel P, Clifford CWG, McNally GP (2019) Paraventricular thalamus controls behavior during motivational conflict. J Neurosci 39(25):4945\u20134958. https:\/\/doi.org\/10.1523\/JNEUROSCI.2480-18.2019","journal-title":"J Neurosci"},{"issue":"7833","key":"2534_CR38","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1038\/s41586-020-2860-1","volume":"587","author":"S Choi","year":"2020","unstructured":"Choi S, Hachisuka J, Brett MA, Magee AR, Omori Y, Iqbal NU, Zhang D, DeLisle MM, Wolfson RL, Bai L, Santiago C, Gong S, Goulding M, Heintz N, Koerber HR, Ross SE, Ginty DD (2020) Parallel ascending spinal pathways for affective touch and pain. Nature 587(7833):258\u2013263. https:\/\/doi.org\/10.1038\/s41586-020-2860-1","journal-title":"Nature"},{"key":"2534_CR39","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.neubiorev.2014.11.021","volume":"54","author":"V Colavito","year":"2015","unstructured":"Colavito V, Tesoriero C, Wirtu AT, Grassi-Zucconi G, Bentivoglio M (2015) Limbic thalamus and state-dependent behavior: the paraventricular nucleus of the thalamic midline as a node in circadian timing and sleep\/wake-regulatory networks. Neurosci Biobehav Rev 54:3\u201317. https:\/\/doi.org\/10.1016\/j.neubiorev.2014.11.021","journal-title":"Neurosci Biobehav Rev"},{"issue":"1","key":"2534_CR40","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/0306-4522(89)90239-x","volume":"28","author":"SK Coles","year":"1989","unstructured":"Coles SK, Iles JF, Nicolopoulos-Stournaras S (1989) The mesencephalic centre controlling locomotion in the rat. Neuroscience 28(1):149\u2013157. https:\/\/doi.org\/10.1016\/0306-4522(89)90239-x","journal-title":"Neuroscience"},{"issue":"3","key":"2534_CR41","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1016\/0306-4522(88)90085-1","volume":"24","author":"J Cornwall","year":"1988","unstructured":"Cornwall J, Phillipson OT (1988) Afferent projections to the dorsal thalamus of the rat as shown by retrograde lectin transport\u2014I. The mediodorsal nucleus. Neuroscience 24(3):1035\u20131049","journal-title":"Neuroscience"},{"issue":"2","key":"2534_CR42","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1152\/physrev.1994.74.2.323","volume":"74","author":"RA Dampney","year":"1994","unstructured":"Dampney RA (1994) Functional organization of central pathways regulating the cardiovascular system. Physiol Rev 74(2):323\u2013364. https:\/\/doi.org\/10.1152\/physrev.1994.74.2.323","journal-title":"Physiol Rev"},{"key":"2534_CR43","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1111\/j.1749-6632.1999.tb09273.x","volume":"877","author":"M Davis","year":"1999","unstructured":"Davis M, Shi C (1999) The extended amygdala: are the central nucleus of the amygdala and the bed nucleus of the stria terminalis differentially involved in fear versus anxiety? Ann N Y Acad Sci 877:281\u2013291","journal-title":"Ann N Y Acad Sci"},{"key":"2534_CR44","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/B978-012547638-6\/50020-1","volume-title":"The rat nervous system","author":"JS de Olmos","year":"2004","unstructured":"de Olmos JS, Beltramino CA, Alheid GF (2004) Amygdala and extended amygdala of the rat: a cytoarchitectonical, fibroarchitectonical, and chemoarchitectonical survey. In: Paxinos G (ed) The rat nervous system, 3rd edn. Academic Press, New York, pp 509\u2013603","edition":"3"},{"issue":"5","key":"2534_CR45","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1016\/j.neuron.2020.06.017","volume":"107","author":"J Deng","year":"2020","unstructured":"Deng J, Zhou H, Lin JK, Shen ZX, Chen WZ, Wang LH, Li Q, Mu D, Wei YC, Xu XH, Sun YG (2020) The parabrachial nucleus directly channels spinal nociceptive signals to the intralaminar thalamic nuclei, but not the amygdala. Neuron 107(5):909-923 e906. https:\/\/doi.org\/10.1016\/j.neuron.2020.06.017","journal-title":"Neuron"},{"key":"2534_CR46","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/S0079-6123(06)60009-5","volume":"160","author":"JM Deniau","year":"2007","unstructured":"Deniau JM, Mailly P, Maurice N, Charpier S (2007) The pars reticulata of the substantia nigra: a window to basal ganglia output. Prog Brain Res 160:151\u2013172. https:\/\/doi.org\/10.1016\/S0079-6123(06)60009-5","journal-title":"Prog Brain Res"},{"issue":"4","key":"2534_CR47","doi-asserted-by":"publisher","first-page":"1486","DOI":"10.1523\/JNEUROSCI.4269-12.2013","volume":"33","author":"SD DePuy","year":"2013","unstructured":"DePuy SD, Stornetta RL, Bochorishvili G, Deisseroth K, Witten I, Coates M, Guyenet PG (2013) Glutamatergic neurotransmission between the C1 neurons and the parasympathetic preganglionic neurons of the dorsal motor nucleus of the vagus. J Neurosci 33(4):1486\u20131497. https:\/\/doi.org\/10.1523\/JNEUROSCI.4269-12.2013","journal-title":"J Neurosci"},{"issue":"3","key":"2534_CR48","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/s0091-3057(01)00689-x","volume":"71","author":"JA DiMicco","year":"2002","unstructured":"DiMicco JA, Samuels BC, Zaretskaia MV, Zaretsky DV (2002) The dorsomedial hypothalamus and the response to stress: part renaissance, part revolution. Pharmacol Biochem Behav 71(3):469\u2013480. https:\/\/doi.org\/10.1016\/s0091-3057(01)00689-x","journal-title":"Pharmacol Biochem Behav"},{"issue":"7544","key":"2534_CR49","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1038\/nature14030","volume":"519","author":"FH Do-Monte","year":"2015","unstructured":"Do-Monte FH, Quinones-Laracuente K, Quirk GJ (2015) A temporal shift in the circuits mediating retrieval of fear memory. Nature 519(7544):460\u2013463. https:\/\/doi.org\/10.1038\/nature14030","journal-title":"Nature"},{"issue":"2","key":"2534_CR50","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/j.neuron.2017.03.036","volume":"94","author":"FH Do-Monte","year":"2017","unstructured":"Do-Monte FH, Minier-Toribio A, Quinones-Laracuente K, Medina-Colon EM, Quirk GJ (2017) Thalamic regulation of sucrose seeking during unexpected reward omission. Neuron 94(2):388-400 e384. https:\/\/doi.org\/10.1016\/j.neuron.2017.03.036","journal-title":"Neuron"},{"issue":"9","key":"2534_CR51","doi-asserted-by":"publisher","first-page":"3927","DOI":"10.1007\/s00429-017-1445-8","volume":"222","author":"X Dong","year":"2017","unstructured":"Dong X, Li S, Kirouac GJ (2017) Collateralization of projections from the paraventricular nucleus of the thalamus to the nucleus accumbens, bed nucleus of the stria terminalis, and central nucleus of the amygdala. Brain Struct Funct 222(9):3927\u20133943. https:\/\/doi.org\/10.1007\/s00429-017-1445-8","journal-title":"Brain Struct Funct"},{"key":"2534_CR52","doi-asserted-by":"publisher","DOI":"10.1016\/j.ynstr.2020.100266","volume":"13","author":"X Dong","year":"2020","unstructured":"Dong X, Li S, Kirouac GJ (2020) A projection from the paraventricular nucleus of the thalamus to the shell of the nucleus accumbens contributes to footshock stress-induced social avoidance. Neurobiol Stress 13:100266. https:\/\/doi.org\/10.1016\/j.ynstr.2020.100266","journal-title":"Neurobiol Stress"},{"issue":"5","key":"2534_CR53","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1016\/j.neuron.2014.04.042","volume":"82","author":"S Duvarci","year":"2014","unstructured":"Duvarci S, Pare D (2014) Amygdala microcircuits controlling learned fear. Neuron 82(5):966\u2013980. https:\/\/doi.org\/10.1016\/j.neuron.2014.04.042","journal-title":"Neuron"},{"key":"2534_CR54","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.brainres.2011.08.028","volume":"1420","author":"M Ebrahimzadeh","year":"2011","unstructured":"Ebrahimzadeh M, Haghparast A (2011) Analgesic effects of cannabinoid receptor agonist WIN55,212\u20132 in the nucleus cuneiformis in animal models of acute and inflammatory pain in rats. Brain Res 1420:19\u201328. https:\/\/doi.org\/10.1016\/j.brainres.2011.08.028","journal-title":"Brain Res"},{"issue":"10","key":"2534_CR55","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1242\/dmm.026120","volume":"9","author":"B Ellenbroek","year":"2016","unstructured":"Ellenbroek B, Youn J (2016) Rodent models in neuroscience research: is it a rat race? Dis Model Mech 9(10):1079\u20131087. https:\/\/doi.org\/10.1242\/dmm.026120","journal-title":"Dis Model Mech"},{"issue":"1","key":"2534_CR56","doi-asserted-by":"publisher","first-page":"2517","DOI":"10.1038\/s41467-021-22730-y","volume":"12","author":"DS Engelke","year":"2021","unstructured":"Engelke DS, Zhang XO, O\u2019Malley JJ, Fernandez-Leon JA, Li S, Kirouac GJ, Beierlein M, Do-Monte FH (2021) A hypothalamic-thalamostriatal circuit that controls approach-avoidance conflict in rats. Nat Commun 12(1):2517. https:\/\/doi.org\/10.1038\/s41467-021-22730-y","journal-title":"Nat Commun"},{"key":"2534_CR57","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.conb.2018.02.009","volume":"49","author":"JP Fadok","year":"2018","unstructured":"Fadok JP, Markovic M, Tovote P, Luthi A (2018) New perspectives on central amygdala function. Curr Opin Neurobiol 49:141\u2013147. https:\/\/doi.org\/10.1016\/j.conb.2018.02.009","journal-title":"Curr Opin Neurobiol"},{"key":"2534_CR58","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.neuroscience.2011.03.018","volume":"184","author":"MA Fontes","year":"2011","unstructured":"Fontes MA, Xavier CH, de Menezes RC, Dimicco JA (2011) The dorsomedial hypothalamus and the central pathways involved in the cardiovascular response to emotional stress. Neuroscience 184:64\u201374. https:\/\/doi.org\/10.1016\/j.neuroscience.2011.03.018","journal-title":"Neuroscience"},{"issue":"5","key":"2534_CR59","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.tins.2015.03.002","volume":"38","author":"AS Fox","year":"2015","unstructured":"Fox AS, Oler JA, do Tromp PM, Fudge JL, Kalin NH (2015) Extending the amygdala in theories of threat processing. Trends Neurosci 38(5):319\u2013329. https:\/\/doi.org\/10.1016\/j.tins.2015.03.002","journal-title":"Trends Neurosci"},{"issue":"5","key":"2534_CR60","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1002\/cne.22559","volume":"519","author":"PM Fuller","year":"2011","unstructured":"Fuller PM, Sherman D, Pedersen NP, Saper CB, Lu J (2011) Reassessment of the structural basis of the ascending arousal system. J Comp Neurol 519(5):933\u2013956. https:\/\/doi.org\/10.1002\/cne.22559","journal-title":"J Comp Neurol"},{"issue":"2","key":"2534_CR61","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.pneurobio.2009.10.012","volume":"90","author":"K Fuxe","year":"2010","unstructured":"Fuxe K, Dahlstrom AB, Jonsson G, Marcellino D, Guescini M, Dam M, Manger P, Agnati L (2010) The discovery of central monoamine neurons gave volume transmission to the wired brain. Prog Neurobiol 90(2):82\u2013100. https:\/\/doi.org\/10.1016\/j.pneurobio.2009.10.012","journal-title":"Prog Neurobiol"},{"issue":"6","key":"2534_CR62","doi-asserted-by":"publisher","first-page":"1030","DOI":"10.1016\/j.cmet.2014.11.006","volume":"20","author":"AS Garfield","year":"2014","unstructured":"Garfield AS, Shah BP, Madara JC, Burke LK, Patterson CM, Flak J, Neve RL, Evans ML, Lowell BB, Myers MG Jr, Heisler LK (2014) A parabrachial-hypothalamic cholecystokinin neurocircuit controls counterregulatory responses to hypoglycemia. Cell Metab 20(6):1030\u20131037. https:\/\/doi.org\/10.1016\/j.cmet.2014.11.006","journal-title":"Cell Metab"},{"issue":"2","key":"2534_CR63","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1113\/eph8702357","volume":"87","author":"C Gauriau","year":"2002","unstructured":"Gauriau C, Bernard JF (2002) Pain pathways and parabrachial circuits in the rat. Exp Physiol 87(2):251\u2013258","journal-title":"Exp Physiol"},{"issue":"1","key":"2534_CR64","doi-asserted-by":"publisher","first-page":"R41","DOI":"10.1152\/ajpregu.00094.2015","volume":"310","author":"JC Geerling","year":"2016","unstructured":"Geerling JC, Kim M, Mahoney CE, Abbott SB, Agostinelli LJ, Garfield AS, Krashes MJ, Lowell BB, Scammell TE (2016) Genetic identity of thermosensory relay neurons in the lateral parabrachial nucleus. Am J Physiol Regul Integr Comp Physiol 310(1):R41-54. https:\/\/doi.org\/10.1152\/ajpregu.00094.2015","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"8","key":"2534_CR65","doi-asserted-by":"publisher","first-page":"1844","DOI":"10.1002\/cne.24164","volume":"525","author":"JC Geerling","year":"2017","unstructured":"Geerling JC, Yokota S, Rukhadze I, Roe D, Chamberlin NL (2017) Kolliker-Fuse GABAergic and glutamatergic neurons project to distinct targets. J Comp Neurol 525(8):1844\u20131860. https:\/\/doi.org\/10.1002\/cne.24164","journal-title":"J Comp Neurol"},{"key":"2534_CR66","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.55585","author":"DA Gehrlach","year":"2020","unstructured":"Gehrlach DA, Weiand C, Gaitanos TN, Cho E, Klein AS, Hennrich AA, Conzelmann KK, Gogolla N (2020) A whole-brain connectivity map of mouse insular cortex. Elife. https:\/\/doi.org\/10.7554\/eLife.55585","journal-title":"Elife"},{"issue":"5","key":"2534_CR67","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.tins.2019.03.004","volume":"42","author":"DT George","year":"2019","unstructured":"George DT, Ameli R, Koob GF (2019) Periaqueductal gray sheds light on dark areas of psychopathology. Trends Neurosci 42(5):349\u2013360. https:\/\/doi.org\/10.1016\/j.tins.2019.03.004","journal-title":"Trends Neurosci"},{"issue":"Pt 3","key":"2534_CR68","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1113\/jphysiol.2003.056622","volume":"556","author":"H Gong","year":"2004","unstructured":"Gong H, McGinty D, Guzman-Marin R, Chew KT, Stewart D, Szymusiak R (2004) Activation of c-fos in GABAergic neurones in the preoptic area during sleep and in response to sleep deprivation. J Physiol 556(Pt 3):935\u2013946. https:\/\/doi.org\/10.1113\/jphysiol.2003.056622","journal-title":"J Physiol"},{"issue":"2","key":"2534_CR69","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1002\/cne.902970203","volume":"297","author":"C Gonzales","year":"1990","unstructured":"Gonzales C, Chesselet MF (1990) Amygdalonigral pathway: an anterograde study in the rat with Phaseolus vulgaris leucoagglutinin (PHA-L). J Comp Neurol 297(2):182\u2013200. https:\/\/doi.org\/10.1002\/cne.902970203","journal-title":"J Comp Neurol"},{"issue":"4","key":"2534_CR70","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1002\/cne.11036","volume":"469","author":"M Goto","year":"2004","unstructured":"Goto M, Swanson LW (2004) Axonal projections from the parasubthalamic nucleus. J Comp Neurol 469(4):581\u2013607. https:\/\/doi.org\/10.1002\/cne.11036","journal-title":"J Comp Neurol"},{"issue":"31","key":"2534_CR71","doi-asserted-by":"publisher","first-page":"8038","DOI":"10.1523\/JNEUROSCI.0856-16.2016","volume":"36","author":"NZ Gungor","year":"2016","unstructured":"Gungor NZ, Pare D (2016) Functional heterogeneity in the bed nucleus of the stria terminalis. J Neurosci 36(31):8038\u20138049. https:\/\/doi.org\/10.1523\/JNEUROSCI.0856-16.2016","journal-title":"J Neurosci"},{"issue":"5","key":"2534_CR72","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1038\/nrn1902","volume":"7","author":"PG Guyenet","year":"2006","unstructured":"Guyenet PG (2006) The sympathetic control of blood pressure. Nat Rev Neurosci 7(5):335\u2013346. https:\/\/doi.org\/10.1038\/nrn1902","journal-title":"Nat Rev Neurosci"},{"issue":"3","key":"2534_CR73","doi-asserted-by":"publisher","first-page":"R187","DOI":"10.1152\/ajpregu.00054.2013","volume":"305","author":"PG Guyenet","year":"2013","unstructured":"Guyenet PG, Stornetta RL, Bochorishvili G, Depuy SD, Burke PG, Abbott SB (2013) C1 neurons: the body\u2019s EMTs. Am J Physiol Regul Integr Comp Physiol 305(3):R187-204. https:\/\/doi.org\/10.1152\/ajpregu.00054.2013","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"1","key":"2534_CR74","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.jpain.2009.05.005","volume":"11","author":"A Haghparast","year":"2010","unstructured":"Haghparast A, Naderi N, Khani A, Lashgari R, Motamedi F (2010) Formalin-induced differential activation of nucleus cuneiformis neurons in the rat: an electrophysiological study. J Pain 11(1):32\u201343. https:\/\/doi.org\/10.1016\/j.jpain.2009.05.005","journal-title":"J Pain"},{"issue":"2","key":"2534_CR75","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/j.cell.2015.05.057","volume":"162","author":"S Han","year":"2015","unstructured":"Han S, Soleiman MT, Soden ME, Zweifel LS, Palmiter RD (2015) Elucidating an affective pain circuit that creates a threat memory. Cell 162(2):363\u2013374. https:\/\/doi.org\/10.1016\/j.cell.2015.05.057","journal-title":"Cell"},{"issue":"51","key":"2534_CR76","doi-asserted-by":"publisher","first-page":"21906","DOI":"10.1073\/pnas.0912022106","volume":"106","author":"J Hao","year":"2009","unstructured":"Hao J, Wang XD, Dan Y, Poo MM, Zhang XH (2009) An arithmetic rule for spatial summation of excitatory and inhibitory inputs in pyramidal neurons. Proc Natl Acad Sci USA 106(51):21906\u201321911. https:\/\/doi.org\/10.1073\/pnas.0912022106","journal-title":"Proc Natl Acad Sci USA"},{"issue":"4","key":"2534_CR77","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1002\/cne.902930404","volume":"293","author":"H Herbert","year":"1990","unstructured":"Herbert H, Moga MM, Saper CB (1990) Connections of the parabrachial nucleus with the nucleus of the solitary tract and the medullary reticular formation in the rat. J Comp Neurol 293(4):540\u2013580. https:\/\/doi.org\/10.1002\/cne.902930404","journal-title":"J Comp Neurol"},{"issue":"12","key":"2534_CR78","doi-asserted-by":"publisher","first-page":"4738","DOI":"10.1210\/en.2011-1652","volume":"152","author":"W Heydendael","year":"2011","unstructured":"Heydendael W, Sharma K, Iyer V, Luz S, Piel D, Beck S, Bhatnagar S (2011) Orexins\/hypocretins act in the posterior paraventricular thalamic nucleus during repeated stress to regulate facilitation to novel stress. Endocrinology 152(12):4738\u20134752. https:\/\/doi.org\/10.1210\/en.2011-1652","journal-title":"Endocrinology"},{"key":"2534_CR80","doi-asserted-by":"publisher","first-page":"73","DOI":"10.3389\/fnbeh.2014.00073","volume":"8","author":"DT Hsu","year":"2014","unstructured":"Hsu DT, Kirouac GJ, Zubieta JK, Bhatnagar S (2014) Contributions of the paraventricular thalamic nucleus in the regulation of stress, motivation, and mood. Front Behav Neurosci 8:73. https:\/\/doi.org\/10.3389\/fnbeh.2014.00073","journal-title":"Front Behav Neurosci"},{"issue":"24","key":"2534_CR81","doi-asserted-by":"publisher","first-page":"3948","DOI":"10.1016\/j.cub.2018.11.020","volume":"28","author":"R Hua","year":"2018","unstructured":"Hua R, Wang X, Chen X, Wang X, Huang P, Li P, Mei W, Li H (2018) Calretinin neurons in the midline thalamus modulate starvation-induced arousal. Curr Biol 28(24):3948-3959 e3944. https:\/\/doi.org\/10.1016\/j.cub.2018.11.020","journal-title":"Curr Biol"},{"issue":"4","key":"2534_CR82","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1002\/cne.24975","volume":"529","author":"D Huang","year":"2021","unstructured":"Huang D, Grady FS, Peltekian L, Geerling JC (2021a) Efferent projections of Vglut2, Foxp2, and Pdyn parabrachial neurons in mice. J Comp Neurol 529(4):657\u2013693. https:\/\/doi.org\/10.1002\/cne.24975","journal-title":"J Comp Neurol"},{"issue":"11","key":"2534_CR83","doi-asserted-by":"publisher","first-page":"2911","DOI":"10.1002\/cne.25136","volume":"529","author":"D Huang","year":"2021","unstructured":"Huang D, Grady FS, Peltekian L, Laing JJ, Geerling JC (2021b) Efferent projections of CGRP\/Calca-expressing parabrachial neurons in mice. J Comp Neurol 529(11):2911\u20132957. https:\/\/doi.org\/10.1002\/cne.25136","journal-title":"J Comp Neurol"},{"issue":"11","key":"2534_CR84","doi-asserted-by":"publisher","first-page":"R741","DOI":"10.1016\/j.cub.2021.04.001","volume":"31","author":"T Isa","year":"2021","unstructured":"Isa T, Marquez-Legorreta E, Grillner S, Scott EK (2021) The tectum\/superior colliculus as the vertebrate solution for spatial sensory integration and action. Curr Biol 31(11):R741\u2013R762. https:\/\/doi.org\/10.1016\/j.cub.2021.04.001","journal-title":"Curr Biol"},{"issue":"1","key":"2534_CR85","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1186\/s13041-021-00807-5","volume":"14","author":"M Ito","year":"2021","unstructured":"Ito M, Nagase M, Tohyama S, Mikami K, Kato F, Watabe AM (2021) The parabrachial-to-amygdala pathway provides aversive information to induce avoidance behavior in mice. Mol Brain 14(1):94. https:\/\/doi.org\/10.1186\/s13041-021-00807-5","journal-title":"Mol Brain"},{"issue":"10","key":"2534_CR86","doi-asserted-by":"publisher","first-page":"4917","DOI":"10.1210\/en.2005-1393","volume":"147","author":"A Jaferi","year":"2006","unstructured":"Jaferi A, Bhatnagar S (2006) Corticosterone can act at the posterior paraventricular thalamus to inhibit hypothalamic-pituitary-adrenal activity in animals that habituate to repeated stress. Endocrinology 147(10):4917\u20134930","journal-title":"Endocrinology"},{"issue":"3","key":"2534_CR87","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/S0031-9384(03)00014-3","volume":"78","author":"A Jaferi","year":"2003","unstructured":"Jaferi A, Nowak N, Bhatnagar S (2003) Negative feedback functions in chronically stressed rats: role of the posterior paraventricular thalamus. Physiol Behav 78(3):365\u2013373","journal-title":"Physiol Behav"},{"key":"2534_CR88","doi-asserted-by":"publisher","DOI":"10.1016\/j.ynstr.2020.100247","volume":"13","author":"AA Jaramillo","year":"2020","unstructured":"Jaramillo AA, Williford KM, Marshall C, Winder DG, Centanni SW (2020) BNST transient activity associates with approach behavior in a stressful environment and is modulated by the parabrachial nucleus. Neurobiol Stress 13:100247. https:\/\/doi.org\/10.1016\/j.ynstr.2020.100247","journal-title":"Neurobiol Stress"},{"key":"2534_CR89","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2021.108757","volume":"198","author":"AA Jaramillo","year":"2021","unstructured":"Jaramillo AA, Brown JA, Winder DG (2021) Danger and distress: parabrachial-extended amygdala circuits. Neuropharmacology 198:108757. https:\/\/doi.org\/10.1016\/j.neuropharm.2021.108757","journal-title":"Neuropharmacology"},{"issue":"10","key":"2534_CR90","doi-asserted-by":"publisher","first-page":"3751","DOI":"10.1523\/JNEUROSCI.17-10-03751.1997","volume":"17","author":"L Jasmin","year":"1997","unstructured":"Jasmin L, Burkey AR, Card JP, Basbaum AI (1997) Transneuronal labeling of a nociceptive pathway, the spino-(trigemino-)parabrachio-amygdaloid, in the rat. J Neurosci 17(10):3751\u20133765","journal-title":"J Neurosci"},{"key":"2534_CR91","first-page":"155","volume-title":"The rat nervous system","author":"BE Jones","year":"1995","unstructured":"Jones BE (1995) Reticular formation: cytoarchitecture, transmitters, and projections. In: Paxinos G (ed) The rat nervous system. Academic Press, San Diego, pp 155\u2013171"},{"issue":"1","key":"2534_CR92","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1038\/s41386-019-0444-2","volume":"45","author":"BE Jones","year":"2020","unstructured":"Jones BE (2020) Arousal and sleep circuits. Neuropsychopharmacology 45(1):6\u201320. https:\/\/doi.org\/10.1038\/s41386-019-0444-2","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"2534_CR93","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.brainresrev.2007.07.019","volume":"57","author":"LM Jordan","year":"2008","unstructured":"Jordan LM, Liu J, Hedlund PB, Akay T, Pearson KG (2008) Descending command systems for the initiation of locomotion in mammals. Brain Res Rev 57(1):183\u2013191. https:\/\/doi.org\/10.1016\/j.brainresrev.2007.07.019","journal-title":"Brain Res Rev"},{"key":"2534_CR94","first-page":"207","volume-title":"Principles of neuroscience","author":"ER Kandel","year":"2000","unstructured":"Kandel ER, Siegelbaum SA (2000) Synaptic integration. In: Kandel ER, Schwartz JH, Jessell TM (eds) Principles of neuroscience. McGraw-Hill, New York, pp 207\u2013228"},{"issue":"18","key":"2534_CR95","doi-asserted-by":"publisher","first-page":"7627","DOI":"10.1523\/JNEUROSCI.0173-13.2013","volume":"33","author":"S Kaur","year":"2013","unstructured":"Kaur S, Pedersen NP, Yokota S, Hur EE, Fuller PM, Lazarus M, Chamberlin NL, Saper CB (2013) Glutamatergic signaling from the parabrachial nucleus plays a critical role in hypercapnic arousal. J Neurosci 33(18):7627\u20137640. https:\/\/doi.org\/10.1523\/JNEUROSCI.0173-13.2013","journal-title":"J Neurosci"},{"issue":"5","key":"2534_CR96","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1016\/j.neuron.2017.10.009","volume":"96","author":"S Kaur","year":"2017","unstructured":"Kaur S, Wang JL, Ferrari L, Thankachan S, Kroeger D, Venner A, Lazarus M, Wellman A, Arrigoni E, Fuller PM, Saper CB (2017) A genetically defined circuit for arousal from sleep during hypercapnia. Neuron 96(5):1153-1167 e1155. https:\/\/doi.org\/10.1016\/j.neuron.2017.10.009","journal-title":"Neuron"},{"issue":"7803","key":"2534_CR97","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1038\/s41586-020-2167-2","volume":"580","author":"DY Kim","year":"2020","unstructured":"Kim DY, Heo G, Kim M, Kim H, Jin JA, Kim HK, Jung S, An M, Ahn BH, Park JH, Park HE, Lee M, Lee JW, Schwartz GJ, Kim SY (2020) A neural circuit mechanism for mechanosensory feedback control of ingestion. Nature 580(7803):376\u2013380. https:\/\/doi.org\/10.1038\/s41586-020-2167-2","journal-title":"Nature"},{"key":"2534_CR98","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/j.neubiorev.2015.08.005","volume":"56","author":"GJ Kirouac","year":"2015","unstructured":"Kirouac GJ (2015) Placing the paraventricular nucleus of the thalamus within the brain circuits that control behavior. Neurosci Biobehav Rev 56:315\u2013329. https:\/\/doi.org\/10.1016\/j.neubiorev.2015.08.005","journal-title":"Neurosci Biobehav Rev"},{"key":"2534_CR99","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2021.627633","volume":"15","author":"GJ Kirouac","year":"2021","unstructured":"Kirouac GJ (2021) The paraventricular nucleus of the thalamus as an integrating and relay node in the brain anxiety network. Front Behav Neurosci 15:627633. https:\/\/doi.org\/10.3389\/fnbeh.2021.627633","journal-title":"Front Behav Neurosci"},{"issue":"2","key":"2534_CR100","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.brainres.2005.08.035","volume":"1059","author":"GJ Kirouac","year":"2005","unstructured":"Kirouac GJ, Parsons MP, Li S (2005) Orexin (hypocretin) innervation of the paraventricular nucleus of the thalamus. Brain Res 1059(2):179\u2013188","journal-title":"Brain Res"},{"issue":"2","key":"2534_CR101","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1002\/cne.20971","volume":"497","author":"GJ Kirouac","year":"2006","unstructured":"Kirouac GJ, Parsons MP, Li S (2006) Innervation of the paraventricular nucleus of the thalamus from cocaine- and amphetamine-regulated transcript (CART) containing neurons of the hypothalamus. J Comp Neurol 497(2):155\u2013165","journal-title":"J Comp Neurol"},{"issue":"4","key":"2534_CR102","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1002\/(sici)1096-9861(19980713)396:4<544::aid-cne10>3.0.co;2-g","volume":"396","author":"CI Kolmac","year":"1998","unstructured":"Kolmac CI, Power BD, Mitrofanis J (1998) Patterns of connections between zona incerta and brainstem in rats. J Comp Neurol 396(4):544\u2013555. https:\/\/doi.org\/10.1002\/(sici)1096-9861(19980713)396:4%3c544::aid-cne10%3e3.0.co;2-g","journal-title":"J Comp Neurol"},{"issue":"3","key":"2534_CR103","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1002\/1096-9861(20001218)428:3<475::AID-CNE6>3.0.CO;2-9","volume":"428","author":"KE Krout","year":"2000","unstructured":"Krout KE, Loewy AD (2000a) Parabrachial nucleus projections to midline and intralaminar thalamic nuclei of the rat. J Comp Neurol 428(3):475\u2013494","journal-title":"J Comp Neurol"},{"issue":"1","key":"2534_CR104","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1002\/1096-9861(20000814)424:1<111::AID-CNE9>3.0.CO;2-3","volume":"424","author":"KE Krout","year":"2000","unstructured":"Krout KE, Loewy AD (2000b) Periaqueductal gray matter projections to midline and intralaminar thalamic nuclei of the rat. J Comp Neurol 424(1):111\u2013141","journal-title":"J Comp Neurol"},{"issue":"1","key":"2534_CR105","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1002\/cne.10236","volume":"448","author":"KE Krout","year":"2002","unstructured":"Krout KE, Belzer RE, Loewy AD (2002) Brainstem projections to midline and intralaminar thalamic nuclei of the rat. J Comp Neurol 448(1):53\u2013101","journal-title":"J Comp Neurol"},{"issue":"3","key":"2534_CR106","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1016\/S0306-4522(02)00997-1","volume":"118","author":"KE Krout","year":"2003","unstructured":"Krout KE, Mettenleiter TC, Loewy AD (2003) Single CNS neurons link both central motor and cardiosympathetic systems: a double-virus tracing study. Neuroscience 118(3):853\u2013866","journal-title":"Neuroscience"},{"issue":"8","key":"2534_CR107","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1038\/nn.4331","volume":"19","author":"G Labouebe","year":"2016","unstructured":"Labouebe G, Boutrel B, Tarussio D, Thorens B (2016) Glucose-responsive neurons of the paraventricular thalamus control sucrose-seeking behavior. Nat Neurosci 19(8):999\u20131002. https:\/\/doi.org\/10.1038\/nn.4331","journal-title":"Nat Neurosci"},{"issue":"11","key":"2534_CR108","doi-asserted-by":"publisher","first-page":"3729","DOI":"10.1016\/j.celrep.2020.02.095","volume":"30","author":"CK Lafferty","year":"2020","unstructured":"Lafferty CK, Yang AK, Mendoza JA, Britt JP (2020) Nucleus accumbens cell type- and input-specific suppression of unproductive reward seeking. Cell Rep 30(11):3729-3742 e3723. https:\/\/doi.org\/10.1016\/j.celrep.2020.02.095","journal-title":"Cell Rep"},{"key":"2534_CR109","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchemneu.2019.101661","volume":"102","author":"TK Lavin","year":"2019","unstructured":"Lavin TK, Jin L, Wickersham IR (2019) Monosynaptic tracing: a step-by-step protocol. J Chem Neuroanat 102:101661. https:\/\/doi.org\/10.1016\/j.jchemneu.2019.101661","journal-title":"J Chem Neuroanat"},{"issue":"4","key":"2534_CR110","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1038\/mp.2016.1","volume":"21","author":"MA Lebow","year":"2016","unstructured":"Lebow MA, Chen A (2016) Overshadowed by the amygdala: the bed nucleus of the stria terminalis emerges as key to psychiatric disorders. Mol Psychiatry 21(4):450\u2013463. https:\/\/doi.org\/10.1038\/mp.2016.1","journal-title":"Mol Psychiatry"},{"issue":"6","key":"2534_CR111","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1016\/j.neuron.2017.11.041","volume":"96","author":"DE Leib","year":"2017","unstructured":"Leib DE, Zimmerman CA, Poormoghaddam A, Huey EL, Ahn JS, Lin YC, Tan CL, Chen Y, Knight ZA (2017) The forebrain thirst circuit drives drinking through negative reinforcement. Neuron 96(6):1272-1281 e1274. https:\/\/doi.org\/10.1016\/j.neuron.2017.11.041","journal-title":"Neuron"},{"key":"2534_CR112","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.cobeha.2018.09.012","volume":"26","author":"B Li","year":"2019","unstructured":"Li B (2019) Central amygdala cells for learning and expressing aversive emotional memories. Curr Opin Behav Sci 26:40\u201345. https:\/\/doi.org\/10.1016\/j.cobeha.2018.09.012","journal-title":"Curr Opin Behav Sci"},{"issue":"2","key":"2534_CR113","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1002\/cne.21502","volume":"506","author":"S Li","year":"2008","unstructured":"Li S, Kirouac GJ (2008) Projections from the paraventricular nucleus of the thalamus to the forebrain, with special emphasis on the extended amygdala. J Comp Neurol 506(2):263\u2013287","journal-title":"J Comp Neurol"},{"issue":"2","key":"2534_CR114","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1007\/s00429-011-0360-7","volume":"217","author":"S Li","year":"2012","unstructured":"Li S, Kirouac GJ (2012) Sources of inputs to the anterior and posterior aspects of the paraventricular nucleus of the thalamus. Brain Struct Funct 217(2):257\u2013273. https:\/\/doi.org\/10.1007\/s00429-011-0360-7","journal-title":"Brain Struct Funct"},{"issue":"2","key":"2534_CR115","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1007\/s00213-010-1948-y","volume":"212","author":"Y Li","year":"2010","unstructured":"Li Y, Li S, Wei C, Wang H, Sui N, Kirouac GJ (2010) Orexins in the paraventricular nucleus of the thalamus mediate anxiety-like responses in rats. Psychopharmacology 212(2):251\u2013265. https:\/\/doi.org\/10.1007\/s00213-010-1948-y","journal-title":"Psychopharmacology"},{"key":"2534_CR116","doi-asserted-by":"publisher","first-page":"136","DOI":"10.3389\/fnana.2014.00136","volume":"8","author":"S Li","year":"2014","unstructured":"Li S, Shi Y, Kirouac GJ (2014) The hypothalamus and periaqueductal gray are the sources of dopamine fibers in the paraventricular nucleus of the thalamus in the rat. Front Neuroanat 8:136. https:\/\/doi.org\/10.3389\/fnana.2014.00136","journal-title":"Front Neuroanat"},{"issue":"6","key":"2534_CR117","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1007\/s00429-021-02289-6","volume":"226","author":"S Li","year":"2021","unstructured":"Li S, Dong X, Kirouac GJ (2021) Extensive divergence of projections to the forebrain from neurons in the paraventricular nucleus of the thalamus. Brain Struct Funct 226(6):1779\u20131802. https:\/\/doi.org\/10.1007\/s00429-021-02289-6","journal-title":"Brain Struct Funct"},{"key":"2534_CR118","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1146\/annurev-neuro-080317-061813","volume":"42","author":"D Liu","year":"2019","unstructured":"Liu D, Dan Y (2019) A motor theory of sleep-wake control: arousal-action circuit. Annu Rev Neurosci 42:27\u201346. https:\/\/doi.org\/10.1146\/annurev-neuro-080317-061813","journal-title":"Annu Rev Neurosci"},{"issue":"1","key":"2534_CR119","doi-asserted-by":"publisher","first-page":"5153","DOI":"10.1038\/s41467-021-25434-5","volume":"12","author":"C Liu","year":"2021","unstructured":"Liu C, Lee CY, Asher G, Cao L, Terakoshi Y, Cao P, Kobayakawa R, Kobayakawa K, Sakurai K, Liu Q (2021a) Author correction: posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice. Nat Commun 12(1):5153. https:\/\/doi.org\/10.1038\/s41467-021-25434-5","journal-title":"Nat Commun"},{"key":"2534_CR120","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2020.135621","volume":"745","author":"J Liu","year":"2021","unstructured":"Liu J, Hu T, Zhang MQ, Xu CY, Yuan MY, Li RX (2021b) Differential efferent projections of GABAergic neurons in the basolateral and central nucleus of amygdala in mice. Neurosci Lett 745:135621. https:\/\/doi.org\/10.1016\/j.neulet.2020.135621","journal-title":"Neurosci Lett"},{"issue":"7660","key":"2534_CR121","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1038\/nature22375","volume":"546","author":"Y Livneh","year":"2017","unstructured":"Livneh Y, Ramesh RN, Burgess CR, Levandowski KM, Madara JC, Fenselau H, Goldey GJ, Diaz VE, Jikomes N, Resch JM, Lowell BB, Andermann ML (2017) Homeostatic circuits selectively gate food cue responses in insular cortex. Nature 546(7660):611\u2013616. https:\/\/doi.org\/10.1038\/nature22375","journal-title":"Nature"},{"key":"2534_CR122","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1016\/B978-0-12-374245-2.00026-7","volume-title":"The rat nervous system","author":"RF Lundry","year":"2015","unstructured":"Lundry RF, Norgren R (2015) Gustatory system. In: Paxinos G (ed) The rat nervous system. Academic Press, San Diego, pp 733\u2013760"},{"key":"2534_CR123","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abd3666","author":"AT Luskin","year":"2021","unstructured":"Luskin AT, Bhatti DL, Mulvey B, Pedersen CE, Girven KS, Oden-Brunson H, Kimbell K, Blackburn T, Sawyer A, Gereau RWt, Dougherty JD, Bruchas MR, (2021) Extended amygdala-parabrachial circuits alter threat assessment and regulate feeding. Sci Adv. https:\/\/doi.org\/10.1126\/sciadv.abd3666","journal-title":"Sci Adv"},{"issue":"11","key":"2534_CR124","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1038\/s41593-018-0251-9","volume":"21","author":"F Matyas","year":"2018","unstructured":"Matyas F, Komlosi G, Babiczky A, Kocsis K, Bartho P, Barsy B, David C, Kanti V, Porrero C, Magyar A, Szucs I, Clasca F, Acsady L (2018) A highly collateralized thalamic cell type with arousal-predicting activity serves as a key hub for graded state transitions in the forebrain. Nat Neurosci 21(11):1551\u20131562. https:\/\/doi.org\/10.1038\/s41593-018-0251-9","journal-title":"Nat Neurosci"},{"key":"2534_CR125","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2020.590528","volume":"14","author":"JF McGinty","year":"2020","unstructured":"McGinty JF, Otis JM (2020) Heterogeneity in the paraventricular thalamus: the traffic light of motivated behaviors. Front Behav Neurosci 14:590528. https:\/\/doi.org\/10.3389\/fnbeh.2020.590528","journal-title":"Front Behav Neurosci"},{"issue":"1","key":"2534_CR126","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/apha.12487","volume":"214","author":"MJ McKinley","year":"2015","unstructured":"McKinley MJ, Yao ST, Uschakov A, McAllen RM, Rundgren M, Martelli D (2015) The median preoptic nucleus: front and centre for the regulation of body fluid, sodium, temperature, sleep and cardiovascular homeostasis. Acta Physiol 214(1):8\u201332. https:\/\/doi.org\/10.1111\/apha.12487","journal-title":"Acta Physiol"},{"issue":"19","key":"2534_CR127","doi-asserted-by":"publisher","first-page":"3298","DOI":"10.1016\/j.cub.2019.07.069","volume":"29","author":"J Meffre","year":"2019","unstructured":"Meffre J, Sicre M, Diarra M, Marchessaux F, Paleressompoulle D, Ambroggi F (2019) Orexin in the posterior paraventricular thalamus mediates hunger-related signals in the nucleus accumbens core. Curr Biol 29(19):3298-3306 e3294. https:\/\/doi.org\/10.1016\/j.cub.2019.07.069","journal-title":"Curr Biol"},{"key":"2534_CR128","volume-title":"Neurobiology of body fluid homeostasis: transduction and integration","author":"JV Menani","year":"2014","unstructured":"Menani JV, Vieira AA, Colombari DSA, De Paula PM, Colombari E, De Luca Jr LA (2014) Preoptic-periventricular integrative mechanisms involved in behavior, fluid-electrolyte balance, and pressor responses. In: Menani JV, Johnson AK, De Luca LA (eds) Neurobiology of body fluid homeostasis: transduction and integration. Taylor & Francis, Milton Park"},{"key":"2534_CR129","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/bs.pbr.2017.07.006","volume":"235","author":"EZ Millan","year":"2017","unstructured":"Millan EZ, Ong Z, McNally GP (2017) Paraventricular thalamus: gateway to feeding, appetitive motivation, and drug addiction. Prog Brain Res 235:113\u2013137. https:\/\/doi.org\/10.1016\/bs.pbr.2017.07.006","journal-title":"Prog Brain Res"},{"issue":"1","key":"2534_CR130","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.neuroscience.2004.08.017","volume":"130","author":"J Mitrofanis","year":"2005","unstructured":"Mitrofanis J (2005) Some certainty for the \u201czone of uncertainty\u201d? Exploring the function of the zona incerta. Neuroscience 130(1):1\u201315. https:\/\/doi.org\/10.1016\/j.neuroscience.2004.08.017","journal-title":"Neuroscience"},{"issue":"5","key":"2534_CR131","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1016\/j.neuron.2013.08.027","volume":"80","author":"K Miyamichi","year":"2013","unstructured":"Miyamichi K, Shlomai-Fuchs Y, Shu M, Weissbourd BC, Luo L, Mizrahi A (2013) Dissecting local circuits: parvalbumin interneurons underlie broad feedback control of olfactory bulb output. Neuron 80(5):1232\u20131245. https:\/\/doi.org\/10.1016\/j.neuron.2013.08.027","journal-title":"Neuron"},{"issue":"3","key":"2534_CR132","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1002\/cne.902410304","volume":"241","author":"MM Moga","year":"1985","unstructured":"Moga MM, Gray TS (1985) Evidence for corticotropin-releasing factor, neurotensin, and somatostatin in the neural pathway from the central nucleus of the amygdala to the parabrachial nucleus. J Comp Neurol 241(3):275\u2013284. https:\/\/doi.org\/10.1002\/cne.902410304","journal-title":"J Comp Neurol"},{"issue":"4","key":"2534_CR133","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1002\/cne.902950408","volume":"295","author":"MM Moga","year":"1990","unstructured":"Moga MM, Herbert H, Hurley KM, Yasui Y, Gray TS, Saper CB (1990) Organization of cortical, basal forebrain, and hypothalamic afferents to the parabrachial nucleus in the rat. J Comp Neurol 295(4):624\u2013661. https:\/\/doi.org\/10.1002\/cne.902950408","journal-title":"J Comp Neurol"},{"issue":"2","key":"2534_CR134","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1002\/cne.903590204","volume":"359","author":"MM Moga","year":"1995","unstructured":"Moga MM, Weis RP, Moore RY (1995) Efferent projections of the paraventricular thalamic nucleus in the rat. J Comp Neurol 359(2):221\u2013238","journal-title":"J Comp Neurol"},{"issue":"1","key":"2534_CR135","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/0300-9629(87)90268-4","volume":"86","author":"Y Moriyama","year":"1987","unstructured":"Moriyama Y (1987) Rhythmical jaw movements and lateral ponto-medullary reticular neurons in rats. Comp Biochem Physiol A Comp Physiol 86(1):7\u201314. https:\/\/doi.org\/10.1016\/0300-9629(87)90268-4","journal-title":"Comp Biochem Physiol A Comp Physiol"},{"issue":"4","key":"2534_CR136","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/0013-4694(49)90219-9","volume":"1","author":"G Moruzzi","year":"1949","unstructured":"Moruzzi G, Magoun HW (1949) Brain stem reticular formation and activation of the EEG. Electroencephalogr Clin Neurophysiol 1(4):455\u2013473","journal-title":"Electroencephalogr Clin Neurophysiol"},{"issue":"3","key":"2534_CR137","doi-asserted-by":"publisher","first-page":"411","DOI":"10.3758\/s13415-018-0590-8","volume":"18","author":"M Mulckhuyse","year":"2018","unstructured":"Mulckhuyse M (2018) The influence of emotional stimuli on the oculomotor system: a review of the literature. Cogn Affect Behav Neurosci 18(3):411\u2013425. https:\/\/doi.org\/10.3758\/s13415-018-0590-8","journal-title":"Cogn Affect Behav Neurosci"},{"issue":"4","key":"2534_CR138","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1007\/s00429-013-0566-y","volume":"219","author":"B Myers","year":"2014","unstructured":"Myers B, Mark Dolgas C, Kasckow J, Cullinan WE, Herman JP (2014) Central stress-integrative circuits: forebrain glutamatergic and GABAergic projections to the dorsomedial hypothalamus, medial preoptic area, and bed nucleus of the stria terminalis. Brain Struct Funct 219(4):1287\u20131303. https:\/\/doi.org\/10.1007\/s00429-013-0566-y","journal-title":"Brain Struct Funct"},{"key":"2534_CR139","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.brainres.2010.08.056","volume":"1358","author":"JG Niu","year":"2010","unstructured":"Niu JG, Yokota S, Tsumori T, Qin Y, Yasui Y (2010) Glutamatergic lateral parabrachial neurons innervate orexin-containing hypothalamic neurons in the rat. Brain Res 1358:110\u2013122. https:\/\/doi.org\/10.1016\/j.brainres.2010.08.056","journal-title":"Brain Res"},{"issue":"4","key":"2534_CR140","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.neures.2004.12.009","volume":"51","author":"K Otake","year":"2005","unstructured":"Otake K (2005) Cholecystokinin and substance P immunoreactive projections to the paraventricular thalamic nucleus in the rat. Neurosci Res 51(4):383\u2013394","journal-title":"Neurosci Res"},{"issue":"1","key":"2534_CR141","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/0304-3940(95)12148-W","volume":"201","author":"K Otake","year":"1995","unstructured":"Otake K, Nakamura Y (1995) Sites of origin of corticotropin-releasing factor-like immunoreactive projection fibers to the paraventricular thalamic nucleus in the rat. Neurosci Lett 201(1):84\u201386","journal-title":"Neurosci Lett"},{"issue":"3 Pt 1","key":"2534_CR142","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.1523\/JNEUROSCI.15-03-01891.1995","volume":"15","author":"K Otake","year":"1995","unstructured":"Otake K, Ruggiero DA (1995) Monoamines and nitric oxide are employed by afferents engaged in midline thalamic regulation. J Neurosci 15(3 Pt 1):1891\u20131911","journal-title":"J Neurosci"},{"issue":"9","key":"2534_CR143","doi-asserted-by":"publisher","first-page":"5694","DOI":"10.1523\/JNEUROSCI.14-09-05694.1994","volume":"14","author":"K Otake","year":"1994","unstructured":"Otake K, Reis DJ, Ruggiero DA (1994) Afferents to the midline thalamus issue collaterals to the nucleus tractus solitarii: an anatomical basis for thalamic and visceral reflex integration. J Neurosci 14(9):5694\u20135707","journal-title":"J Neurosci"},{"issue":"7643","key":"2534_CR144","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1038\/nature21376","volume":"543","author":"JM Otis","year":"2017","unstructured":"Otis JM, Namboodiri VM, Matan AM, Voets ES, Mohorn EP, Kosyk O, McHenry JA, Robinson JE, Resendez SL, Rossi MA, Stuber GD (2017) Prefrontal cortex output circuits guide reward seeking through divergent cue encoding. Nature 543(7643):103\u2013107. https:\/\/doi.org\/10.1038\/nature21376","journal-title":"Nature"},{"issue":"3","key":"2534_CR145","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1016\/j.neuron.2019.05.018","volume":"103","author":"JM Otis","year":"2019","unstructured":"Otis JM, Zhu M, Namboodiri VMK, Cook CA, Kosyk O, Matan AM, Ying R, Hashikawa Y, Hashikawa K, Trujillo-Pisanty I, Guo J, Ung RL, Rodriguez-Romaguera J, Anton ES, Stuber GD (2019) Paraventricular thalamus projection neurons integrate cortical and hypothalamic signals for cue-reward processing. Neuron 103(3):423-431 e424. https:\/\/doi.org\/10.1016\/j.neuron.2019.05.018","journal-title":"Neuron"},{"issue":"1","key":"2534_CR146","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.neuropharm.2011.08.037","volume":"62","author":"N Padilla-Coreano","year":"2012","unstructured":"Padilla-Coreano N, Do-Monte FH, Quirk GJ (2012) A time-dependent role of midline thalamic nuclei in the retrieval of fear memory. Neuropharmacology 62(1):457\u2013463. https:\/\/doi.org\/10.1016\/j.neuropharm.2011.08.037","journal-title":"Neuropharmacology"},{"issue":"5","key":"2534_CR148","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.tins.2018.03.007","volume":"41","author":"RD Palmiter","year":"2018","unstructured":"Palmiter RD (2018) The parabrachial nucleus: CGRP neurons function as a general alarm. Trends Neurosci 41(5):280\u2013293. https:\/\/doi.org\/10.1016\/j.tins.2018.03.007","journal-title":"Trends Neurosci"},{"issue":"6","key":"2534_CR149","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1002\/cne.21224","volume":"500","author":"MP Parsons","year":"2007","unstructured":"Parsons MP, Li S, Kirouac GJ (2007) Functional and anatomical connection between the paraventricular nucleus of the thalamus and dopamine fibers of the nucleus accumbens. J Comp Neurol 500(6):1050\u20131063","journal-title":"J Comp Neurol"},{"key":"2534_CR150","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10081555","author":"A Patthy","year":"2021","unstructured":"Patthy A, Murai J, Hanics J, Pinter A, Zahola P, Hokfelt TGM, Harkany T, Alpar A (2021) Neuropathology of the brainstem to mechanistically understand and to treat Alzheimer\u2019s disease. J Clin Med. https:\/\/doi.org\/10.3390\/jcm10081555","journal-title":"J Clin Med"},{"key":"2534_CR151","volume-title":"The rat brain in stereotaxic coordinates","author":"G Paxinos","year":"2009","unstructured":"Paxinos G, Watson C (2009) The rat brain in stereotaxic coordinates, 6th edn. Elsevier Academic Press, San Diego","edition":"6"},{"key":"2534_CR152","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2021.03.001","author":"MA Penzo","year":"2021","unstructured":"Penzo MA, Gao C (2021) The paraventricular nucleus of the thalamus: an integrative node underlying homeostatic behavior. Trends Neurosci. https:\/\/doi.org\/10.1016\/j.tins.2021.03.001","journal-title":"Trends Neurosci"},{"issue":"7544","key":"2534_CR153","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1038\/nature13978","volume":"519","author":"MA Penzo","year":"2015","unstructured":"Penzo MA, Robert V, Tucciarone J, De Bundel D, Wang M, Van Aelst L, Darvas M, Parada LF, Palmiter RD, He M, Huang ZJ, Li B (2015) The paraventricular thalamus controls a central amygdala fear circuit. Nature 519(7544):455\u2013459. https:\/\/doi.org\/10.1038\/nature13978","journal-title":"Nature"},{"key":"2534_CR154","doi-asserted-by":"publisher","DOI":"10.4159\/9780674042100","volume-title":"Brain arousal and information theory","author":"D Pfaff","year":"2006","unstructured":"Pfaff D (2006) Brain arousal and information theory. Harvard University Press, Cambridge"},{"key":"2534_CR155","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1196\/annals.1417.019","volume":"1129","author":"D Pfaff","year":"2008","unstructured":"Pfaff D, Ribeiro A, Matthews J, Kow LM (2008) Concepts and mechanisms of generalized central nervous system arousal. Ann N Y Acad Sci 1129:11\u201325","journal-title":"Ann N Y Acad Sci"},{"issue":"1","key":"2534_CR156","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/0304-3940(94)90873-7","volume":"176","author":"OT Phillipson","year":"1994","unstructured":"Phillipson OT, Bohn MC (1994) C1\u20133 adrenergic medullary neurones project to the paraventricular thalamic nucleus in the rat. Neurosci Lett 176(1):67\u201370","journal-title":"Neurosci Lett"},{"key":"2534_CR157","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abe4323","author":"SC Phua","year":"2021","unstructured":"Phua SC, Tan YL, Kok AMY, Senol E, Chiam CJH, Lee CY, Peng Y, Lim ATJ, Mohammad H, Lim JX, Fu Y (2021) A distinct parabrachial-to-lateral hypothalamus circuit for motivational suppression of feeding by nociception. Sci Adv. https:\/\/doi.org\/10.1126\/sciadv.abe4323","journal-title":"Sci Adv"},{"key":"2534_CR158","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-018-0089-2","author":"P Pliota","year":"2018","unstructured":"Pliota P, Bohm V, Grossl F, Griessner J, Valenti O, Kraitsy K, Kaczanowska J, Pasieka M, Lendl T, Deussing JM, Haubensak W (2018) Stress peptides sensitize fear circuitry to promote passive coping. Mol Psychiatry. https:\/\/doi.org\/10.1038\/s41380-018-0089-2","journal-title":"Mol Psychiatry"},{"issue":"17","key":"2534_CR159","doi-asserted-by":"publisher","first-page":"2301","DOI":"10.1016\/j.cub.2016.07.054","volume":"26","author":"MH Qiu","year":"2016","unstructured":"Qiu MH, Chen MC, Fuller PM, Lu J (2016) Stimulation of the pontine parabrachial nucleus promotes wakefulness via extra-thalamic forebrain circuit nodes. Curr Biol 26(17):2301\u20132312. https:\/\/doi.org\/10.1016\/j.cub.2016.07.054","journal-title":"Curr Biol"},{"issue":"6413","key":"2534_CR160","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1126\/science.aat2512","volume":"362","author":"S Ren","year":"2018","unstructured":"Ren S, Wang Y, Yue F, Cheng X, Dang R, Qiao Q, Sun X, Li X, Jiang Q, Yao J, Qin H, Wang G, Liao X, Gao D, Xia J, Zhang J, Hu B, Yan J, Wang Y, Xu M, Han Y, Tang X, Chen X, He C, Hu Z (2018) The paraventricular thalamus is a critical thalamic area for wakefulness. Science 362(6413):429\u2013434. https:\/\/doi.org\/10.1126\/science.aat2512","journal-title":"Science"},{"issue":"2","key":"2534_CR161","doi-asserted-by":"publisher","first-page":"R222","DOI":"10.1152\/ajpregu.00556.2010","volume":"300","author":"L Rinaman","year":"2011","unstructured":"Rinaman L (2011) Hindbrain noradrenergic A2 neurons: diverse roles in autonomic, endocrine, cognitive, and behavioral functions. Am J Physiol Regul Integr Comp Physiol 300(2):R222-235. https:\/\/doi.org\/10.1152\/ajpregu.00556.2010","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"4","key":"2534_CR162","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/j.physbeh.2006.05.036","volume":"89","author":"S Ritter","year":"2006","unstructured":"Ritter S, Dinh TT, Li AJ (2006) Hindbrain catecholamine neurons control multiple glucoregulatory responses. Physiol Behav 89(4):490\u2013500. https:\/\/doi.org\/10.1016\/j.physbeh.2006.05.036","journal-title":"Physiol Behav"},{"issue":"1\u20132","key":"2534_CR163","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/0166-4328(93)90086-6","volume":"58","author":"G Sandner","year":"1993","unstructured":"Sandner G, Oberling P, Silveira MC, Di Scala G, Rocha B, Bagri A, Depoortere R (1993) What brain structures are active during emotions? Effects of brain stimulation elicited aversion on c-fos immunoreactivity and behavior. Behav Brain Res 58(1\u20132):9\u201318. https:\/\/doi.org\/10.1016\/0166-4328(93)90086-6","journal-title":"Behav Brain Res"},{"issue":"2","key":"2534_CR164","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/0006-8993(80)91117-8","volume":"197","author":"CB Saper","year":"1980","unstructured":"Saper CB, Loewy AD (1980) Efferent connections of the parabrachial nucleus in the rat. Brain Res 197(2):291\u2013317","journal-title":"Brain Res"},{"issue":"3","key":"2534_CR165","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.tins.2004.12.009","volume":"28","author":"CB Saper","year":"2005","unstructured":"Saper CB, Lu J, Chou TC, Gooley J (2005) The hypothalamic integrator for circadian rhythms. Trends Neurosci 28(3):152\u2013157. https:\/\/doi.org\/10.1016\/j.tins.2004.12.009","journal-title":"Trends Neurosci"},{"issue":"4","key":"2534_CR167","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1002\/cne.20697","volume":"491","author":"M Sarhan","year":"2005","unstructured":"Sarhan M, Freund-Mercier MJ, Veinante P (2005) Branching patterns of parabrachial neurons projecting to the central extended amgydala: single axonal reconstructions. J Comp Neurol 491(4):418\u2013442. https:\/\/doi.org\/10.1002\/cne.20697","journal-title":"J Comp Neurol"},{"issue":"4","key":"2534_CR168","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1016\/j.neuron.2017.01.014","volume":"93","author":"TE Scammell","year":"2017","unstructured":"Scammell TE, Arrigoni E, Lipton JO (2017) Neural circuitry of wakefulness and sleep. Neuron 93(4):747\u2013765. https:\/\/doi.org\/10.1016\/j.neuron.2017.01.014","journal-title":"Neuron"},{"issue":"8","key":"2534_CR169","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1016\/j.neubiorev.2005.05.006","volume":"29","author":"LC Schenberg","year":"2005","unstructured":"Schenberg LC, Povoa RM, Costa AL, Caldellas AV, Tufik S, Bittencourt AS (2005) Functional specializations within the tectum defense systems of the rat. Neurosci Biobehav Rev 29(8):1279\u20131298. https:\/\/doi.org\/10.1016\/j.neubiorev.2005.05.006","journal-title":"Neurosci Biobehav Rev"},{"issue":"7563","key":"2534_CR170","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1038\/nature14600","volume":"524","author":"LA Schwarz","year":"2015","unstructured":"Schwarz LA, Miyamichi K, Gao XJ, Beier KT, Weissbourd B, DeLoach KE, Ren J, Ibanes S, Malenka RC, Kremer EJ, Luo L (2015) Viral-genetic tracing of the input-output organization of a central noradrenaline circuit. Nature 524(7563):88\u201392. https:\/\/doi.org\/10.1038\/nature14600","journal-title":"Nature"},{"key":"2534_CR171","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2021.108906","volume":"204","author":"T Shah","year":"2021","unstructured":"Shah T, Dunning JL, Contet C (2021) At the heart of the interoception network: influence of the parasubthalamic nucleus on autonomic functions and motivated behaviors. Neuropharmacology 204:108906. https:\/\/doi.org\/10.1016\/j.neuropharm.2021.108906","journal-title":"Neuropharmacology"},{"issue":"2","key":"2534_CR172","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/0306-4522(92)90433-3","volume":"50","author":"SJ Shammah-Lagnado","year":"1992","unstructured":"Shammah-Lagnado SJ, Costa MS, Ricardo JA (1992) Afferent connections of the parvocellular reticular formation: a horseradish peroxidase study in the rat. Neuroscience 50(2):403\u2013425. https:\/\/doi.org\/10.1016\/0306-4522(92)90433-3","journal-title":"Neuroscience"},{"issue":"2","key":"2534_CR173","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1007\/s00429-016-1250-9","volume":"222","author":"S Shipp","year":"2017","unstructured":"Shipp S (2017) The functional logic of corticostriatal connections. Brain Struct Funct 222(2):669\u2013706. https:\/\/doi.org\/10.1007\/s00429-016-1250-9","journal-title":"Brain Struct Funct"},{"issue":"1","key":"2534_CR174","doi-asserted-by":"publisher","first-page":"6218","DOI":"10.1038\/s41467-020-19980-7","volume":"11","author":"B Sofia Beas","year":"2020","unstructured":"Sofia Beas B, Gu X, Leng Y, Koita O, Rodriguez-Gonzalez S, Kindel M, Matikainen-Ankney BA, Larsen RS, Kravitz AV, Hoon MA, Penzo MA (2020) A ventrolateral medulla-midline thalamic circuit for hypoglycemic feeding. Nat Commun 11(1):6218. https:\/\/doi.org\/10.1038\/s41467-020-19980-7","journal-title":"Nat Commun"},{"issue":"6","key":"2534_CR175","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1016\/j.neuron.2020.03.016","volume":"106","author":"EE Steinberg","year":"2020","unstructured":"Steinberg EE, Gore F, Heifets BD, Taylor MD, Norville ZC, Beier KT, Foldy C, Lerner TN, Luo L, Deisseroth K, Malenka RC (2020) Amygdala-midbrain connections modulate appetitive and aversive learning. Neuron 106(6):1026-1043 e1029. https:\/\/doi.org\/10.1016\/j.neuron.2020.03.016","journal-title":"Neuron"},{"issue":"4","key":"2534_CR176","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.sleep.2007.03.013","volume":"8","author":"R Szymusiak","year":"2007","unstructured":"Szymusiak R, Gvilia I, McGinty D (2007) Hypothalamic control of sleep. Sleep Med 8(4):291\u2013301. https:\/\/doi.org\/10.1016\/j.sleep.2007.03.013","journal-title":"Sleep Med"},{"issue":"1","key":"2534_CR177","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/0304-3940(90)90513-9","volume":"115","author":"M Takada","year":"1990","unstructured":"Takada M, Campbell KJ, Moriizumi T, Hattori T (1990) On the origin of the dopaminergic innervation of the paraventricular thalamic nucleus. Neurosci Lett 115(1):33\u201336","journal-title":"Neurosci Lett"},{"issue":"1","key":"2534_CR178","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/0014-4886(81)90132-1","volume":"72","author":"M Takatori","year":"1981","unstructured":"Takatori M, Nozaki S, Nakamura Y (1981) Control of trigeminal motoneurons exerted from bulbar reticular formation in the cat. Exp Neurol 72(1):122\u2013140. https:\/\/doi.org\/10.1016\/0014-4886(81)90132-1","journal-title":"Exp Neurol"},{"issue":"1","key":"2534_CR179","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1002\/(SICI)1096-9861(19961202)376:1<143::AID-CNE9>3.0.CO;2-3","volume":"376","author":"RH Thompson","year":"1996","unstructured":"Thompson RH, Canteras NS, Swanson LW (1996) Organization of projections from the dorsomedial nucleus of the hypothalamus: a PHA-L study in the rat. J Comp Neurol 376(1):143\u2013173","journal-title":"J Comp Neurol"},{"issue":"2","key":"2534_CR180","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/j.neuroscience.2009.03.046","volume":"161","author":"K Tokita","year":"2009","unstructured":"Tokita K, Inoue T, Boughter JD Jr (2009) Afferent connections of the parabrachial nucleus in C57BL\/6J mice. Neuroscience 161(2):475\u2013488. https:\/\/doi.org\/10.1016\/j.neuroscience.2009.03.046","journal-title":"Neuroscience"},{"issue":"1","key":"2534_CR181","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1007\/s002219900223","volume":"130","author":"JB Travers","year":"2000","unstructured":"Travers JB, DiNardo LA, Karimnamazi H (2000) Medullary reticular formation activity during ingestion and rejection in the awake rat. Exp Brain Res 130(1):78\u201392. https:\/\/doi.org\/10.1007\/s002219900223","journal-title":"Exp Brain Res"},{"issue":"1","key":"2534_CR182","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/0891-0618(92)90032-l","volume":"5","author":"M Vankova","year":"1992","unstructured":"Vankova M, Arluison M, Leviel V, Tramu G (1992) Afferent connections of the rat substantia nigra pars lateralis with special reference to peptide-containing neurons of the amygdalo-nigral pathway. J Chem Neuroanat 5(1):39\u201350. https:\/\/doi.org\/10.1016\/0891-0618(92)90032-l","journal-title":"J Chem Neuroanat"},{"key":"2534_CR183","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsz023","author":"A Venner","year":"2019","unstructured":"Venner A, Todd WD, Fraigne J, Bowrey H, Eban-Rothschild A, Kaur S, Anaclet C (2019) Newly identified sleep-wake and circadian circuits as potential therapeutic targets. Sleep. https:\/\/doi.org\/10.1093\/sleep\/zsz023","journal-title":"Sleep"},{"issue":"2","key":"2534_CR184","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1002\/cne.21679","volume":"508","author":"RP Vertes","year":"2008","unstructured":"Vertes RP, Hoover WB (2008) Projections of the paraventricular and paratenial nuclei of the dorsal midline thalamus in the rat. J Comp Neurol 508(2):212\u2013237","journal-title":"J Comp Neurol"},{"issue":"5","key":"2534_CR185","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.neuron.2007.01.033","volume":"53","author":"IR Wickersham","year":"2007","unstructured":"Wickersham IR, Lyon DC, Barnard RJ, Mori T, Finke S, Conzelmann KK, Young JA, Callaway EM (2007) Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons. Neuron 53(5):639\u2013647. https:\/\/doi.org\/10.1016\/j.neuron.2007.01.033","journal-title":"Neuron"},{"key":"2534_CR186","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.645877","volume":"15","author":"Q Xu","year":"2021","unstructured":"Xu Q, Wang DR, Dong H, Chen L, Lu J, Lazarus M, Cherasse Y, Chen GH, Qu WM, Huang ZL (2021) Medial parabrachial nucleus is essential in controlling wakefulness in rats. Front Neurosci 15:645877. https:\/\/doi.org\/10.3389\/fnins.2021.645877","journal-title":"Front Neurosci"},{"issue":"3","key":"2534_CR187","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1007\/s00429-018-01825-1","volume":"224","author":"J Ye","year":"2019","unstructured":"Ye J, Veinante P (2019) Cell-type specific parallel circuits in the bed nucleus of the stria terminalis and the central nucleus of the amygdala of the mouse. Brain Struct Funct 224(3):1067\u20131095. https:\/\/doi.org\/10.1007\/s00429-018-01825-1","journal-title":"Brain Struct Funct"},{"issue":"1","key":"2534_CR188","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1002\/1096-9861(20000101)429:1<80::aid-cne7>3.0.co;2-l","volume":"429","author":"F Zerari-Mailly","year":"2001","unstructured":"Zerari-Mailly F, Pinganaud G, Dauvergne C, Buisseret P, Buisseret-Delmas C (2001) Trigemino-reticulo-facial and trigemino-reticulo-hypoglossal pathways in the rat. J Comp Neurol 429(1):80\u201393. https:\/\/doi.org\/10.1002\/1096-9861(20000101)429:1%3c80::aid-cne7%3e3.0.co;2-l","journal-title":"J Comp Neurol"},{"issue":"6340","key":"2534_CR189","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1126\/science.aam7100","volume":"356","author":"X Zhang","year":"2017","unstructured":"Zhang X, van den Pol AN (2017) Rapid binge-like eating and body weight gain driven by zona incerta GABA neuron activation. Science 356(6340):853\u2013859. https:\/\/doi.org\/10.1126\/science.aam7100","journal-title":"Science"},{"issue":"6413","key":"2534_CR190","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1126\/science.aat0481","volume":"362","author":"Y Zhu","year":"2018","unstructured":"Zhu Y, Nachtrab G, Keyes PC, Allen WE, Luo L, Chen X (2018) Dynamic salience processing in paraventricular thalamus gates associative learning. Science 362(6413):423\u2013429. https:\/\/doi.org\/10.1126\/science.aat0481","journal-title":"Science"},{"key":"2534_CR191","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.68372","author":"YB Zhu","year":"2022","unstructured":"Zhu YB, Wang Y, Hua XX, Xu L, Liu MZ, Zhang R, Liu PF, Li JB, Zhang L, Mu D (2022) PBN-PVT projections modulate negative affective states in mice. Elife. https:\/\/doi.org\/10.7554\/eLife.68372","journal-title":"Elife"}],"container-title":["Brain Structure and Function"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00429-022-02534-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00429-022-02534-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00429-022-02534-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T06:09:42Z","timestamp":1661494182000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00429-022-02534-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,15]]},"references-count":188,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["2534"],"URL":"https:\/\/doi.org\/10.1007\/s00429-022-02534-6","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.02.23.481069","asserted-by":"object"}]},"ISSN":["1863-2653","1863-2661"],"issn-type":[{"value":"1863-2653","type":"print"},{"value":"1863-2661","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,15]]},"assertion":[{"value":"23 February 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 June 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 July 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No conflict to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Approved by the University of Manitoba using the Canadian Council on Animal Care guidelines.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"All authors consent to the publication of the manuscript.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}